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Journal of Intercultural Ethnopharmacology

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https://www.readbyqxmd.com/read/27757277/effects-of-a-diet-containing-brazilian-propolis-on-lipopolysaccharide-induced-increases-in-plasma-plasminogen-activator-inhibitor-1-levels-in-mice
#1
Naoki Ohkura, Katsutaka Oishi, Fumiko Kihara-Negishi, Gen-Ichi Atsumi, Tomoki Tatefuji
BACKGROUND: Brazilian propolis has many biological activities including the ability to help prevent thrombotic diseases, but this particular effect has not been proven. Plasma levels of plasminogen activator inhibitor-1 (PAI-1), an inhibitor of fibrinolysis, increase under inflammatory conditions such as infection, obesity and atherosclerosis and such elevated levels predispose individuals to a risk of developing thrombotic diseases. AIM: This study aimed to determine the effects of a diet containing Brazilian propolis on lipopolysaccharide (LPS)-induced increases in plasma PAI-1 levels...
September 2016: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/27757276/evaluation-of-wound-healing-activity-of-cow-urine-ark-in-diabetic-wistar-albino-rats
#2
Hiren N Hirapara, Vishal M Ghori, Ashish P Anovadiya, Chandrabhanu R Tripathi
AIM: To evaluate wound healing activity of cow urine ark in diabetic rats. MATERIALS AND METHODS: Streptozotocin-induced diabetic Wistar albino rats were randomly divided into six groups (n = 6). Three groups - diabetic control, active control (glibenclamide), and treatment (cow urine ark) were operated for excision wounds (EWs). Rats in these groups received distilled water 1 ml/day, glibenclamide 0.5 mg/kg body weight/day, and cow urine ark 5.5 ml/kg body weight/day orally till complete healing of the EWs...
September 2016: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/27757275/in-vitro-and-in-vivo-anthelmintic-effects-of-caesalpinia-bonducella-l-roxb-leaf-extract-on-hymenolepis-diminuta-cestoda-and-syphacia-obvelata-nematoda
#3
Shyamalima Gogoi, Arun K Yadav
BACKGROUND: Leaves of Caesalpinia bonducella (L.) Roxb. have been traditionally used as an herbal remedy to treat the intestinal helminthic infections in traditional medicine of India. AIM: This study was undertaken to evaluate the potential in vitro and in vivo anthelmintic effects of C. bonducella leaf extract against Syphacia obvelata (Nematoda) and Hymenolepis diminuta (Cestoda). MATERIALS AND METHODS: The in vitro anthelmintic activity of the extract was investigated on adult worms of S...
September 2016: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/27757274/effects-of-herbal-medicine-on-human-uterine-tumor-bearing-nude-mice
#4
Mi Hyang Ohh, Seong Jin Kim, Jong Kwon Han, Sok Cheon Pak, Kew-Mahn Chee
AIM: Uterine leiomyomas are the most common benign uterine neoplasms associated with significant morbidity. Herbal formulas capable of restoring yin-yang balance by dispersing blood stasis may be useful for managing fibroid symptoms. MATERIALS AND METHODS: In this study, the antitumor properties of three herbs viz., Trogopterus xanthipes Milen-Edwards, Paeonia lactiflora Pallas, and Ulmus davidiana Planch were evaluated in nude mice injected intravenously with human malignant myomas...
September 2016: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/27757273/evaluation-of-anti-epileptic-activity-of-leaf-extracts-of-punica-granatum-on-experimental-models-of-epilepsy-in-mice
#5
Gollapalle L Viswanatha, Marikunte V Venkataranganna, Nunna Bheema Lingeswara Prasad, Godavarthi Ashok
OBJECTIVES: This study was aimed to examine the anti-epileptic activity of leaf extracts of Punica granatum in experimental models of epilepsy in Swiss albino mice. MATERIALS AND METHODS: Petroleum ether leaf extract of P. granatum (PLPG), methanolic LPG (MLPG), and aqueous LPG (ALPG) extracts of P. granatum leaves was initially evaluated against 6-Hz-induced seizure model; the potent extract was further evaluated against maximal electroshock (MES) and pentylenetetrazole (PTZ)-induced convulsions...
September 2016: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/27757272/effect-of-orlistat-alone-or-in-combination-with-garcinia-cambogia-on-visceral-adiposity-index-in-obese-patients
#6
Hayder M Al-Kuraishy, Ali I Al-Gareeb
AIM: The objective of this study was to estimate the effect of orlistat alone and in combination with Garcinia cambogia on visceral adiposity index (VAI) in obese patients. PATIENTS AND METHODS: A total of 99 obese male patients were recruited with aged range between 37 and 46 years. They were randomized into three equal groups, first group treated with orlistat 120 mg/day, second group treated with G. cambogia 166 mg/day, and third group treated with orlistat 120 mg/day plus G...
September 2016: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/27757271/comparative-evaluation-of-anti-obesity-effect-of-aloe-vera-and-gymnema-sylvestre-supplementation-in-high-fat-diet-fed-c57bl-6j-mice
#7
Ramesh Pothuraju, Raj Kumar Sharma, Sarver Ahmed Rather, Satvinder Singh
BACKGROUND: The aim of the present study was to investigate, anti-obesity effect of Aloe vera (AV), and Gymnema sylvestre (GS) whole extract powders administration to high-fat diet (HFD) fed C57BL/6J mice for 12 weeks. MATERIALS AND METHODS: At the end of experiment, different parameters such as body weight, feed intake, organ weights, fasting blood glucose, oral glucose tolerance test, plasma lipid levels, and expression analysis of adipocytokines were evaluated...
September 2016: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/27757270/inhibitory-effect-of-leaves-extracts-of-ocimum-basilicum-and-ocimum-gratissimum-on-two-key-enzymes-involved-in-obesity-and-hypertension-in-vitro
#8
Emmanuel Anyachukwu Irondi, Samson Olalekan Agboola, Ganiyu Oboh, Aline Augusti Boligon
AIM: To evaluate the phenolics composition and inhibitory effect of the leaves extracts of Ocimum basilicum and Ocimum gratissimum on two key enzymes (pancreatic lipase [PL] and angiotensin 1-converting enzyme [ACE]) involved in obesity and hypertension in vitro. MATERIALS AND METHODS: The phenolics (flavonoids and phenolic acids) were quantified using high-performance liquid chromatography coupled with diode array detection. PL and ACE inhibitory effects; DPPH* and ABTS*(+) scavenging activities of the extracts were tested using spectrophotometric methods...
September 2016: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/27757269/anthelmintic-activity-of-a-standardized-extract-from-the-rhizomes-of-acorus-calamus-linn-acoraceae-against-experimentally-induced-cestodiasis-in-rats
#9
Purobi Nath, Arun K Yadav
BACKGROUND: The rhizomes of a herb Acorus calamus Linn. (Acoraceae) have been widely used as a traditional medicine to cure intestinal-helminthic infections in India and South Africa. AIM: This study was undertaken to investigate the in vivo anthelmintic activity of a standardized methanolic extract obtained from the rhizomes A. calamus in a rodent model. MATERIALS AND METHODS: A methanolic extract obtained from rhizomes of A. calamus was characterized for active principle using nuclear magnetic resonance (1)H NMR, (13)C NMR, mass and infrared spectroscopy...
September 2016: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/27757268/in-vitro-antileishmanial-and-antimalarial-activity-of-selected-plants-of-nepal
#10
Bishnu Joshi, Sarah Hendrickx, Lila Bahadur Magar, Niranjan Parajuli, Pierre Dorny, Louis Maes
BACKGROUND: Nepal is very rich in biodiversity, and no extensive effort has yet been carried out to screen plants that are used by traditional healers against parasitic diseases. The aim of this study was to evaluate the in vitro antileishmanial and antimalarial activity of crude methanolic or ethanolic extracts of 29 plant species that are currently used by local people of Nepal for treating different ailments. METHODS: Crude extracts of leaves, twigs, aerial parts, and/or roots of the selected plants were evaluated for in vitro inhibitory activity against intracellular amastigotes of Leishmania infantum and against erythrocytic stages of Plasmodium falciparum...
September 2016: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/27757267/evaluation-of-the-synergistic-effect-of-allium-sativum-eugenia-jambolana-momordica-charantia-ocimum-sanctum-and-psidium-guajava-on-hepatic-and-intestinal-drug-metabolizing-enzymes-in-rats
#11
Devendra Kumar, Neerja Trivedi, Rakesh K Dixit
AIMS/BACKGROUND: This study was to investigated the synergistic effect of polyherbal formulations (PHF) of Allium sativum L., Eugenia jambolana Lam., Momordica charantia L., Ocimum sanctum Linn., and Psidium guajava L. in the inhibition/induction of hepatic and intestinal cytochrome P450 (CYPs) and Phase-II conjugated drug metabolizing enzymes (DMEs). Consumption of these herbal remedy has been extensively documented for diabetes treatment in Ayurveda. METHODOLOGY: PHF of these five herbs was prepared, and different doses were orally administered to Sprague-Dawley rats of different groups except control group...
September 2016: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/27757266/antidiabetic-and-antioxidant-effects-of-croton-lobatus-l-in-alloxan-induced-diabetic-rats
#12
Taiye Remi Fasola, Blessing Ukwenya, Ademola Adetokunbo Oyagbemi, Temidayo Olutayo Omobowale, Temitayo Olabisi Ajibade
BACKGROUND: Croton lobatus contains a high amount of antioxidant phytochemicals that probably account for its wide use as food and medicine in the traditional communities of West Africa. METHODS: The study evaluated the modulatory role of methanol extract of Croton lobatus leaf on alloxan-induced diabetes and associated cardiovascular complications. Male rats were randomly selected and assigned to one of six groups (A to F) of eight animals each: A (distilled water); B (corn oil); C (Alloxan); D (Alloxan + 100 mg kg-1 Croton lobatus); E: (Alloxan + 200 mg kg-1 C...
September 2016: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/27757265/antibacterial-synergy-between-rosmarinic-acid-and-antibiotics-against-methicillin-resistant-staphylococcus-aureus
#13
Sanmuga Priya Ekambaram, Senthamil Selvan Perumal, Ajay Balakrishnan, Nathiya Marappan, Sabari Srinivasan Gajendran, Vinodhini Viswanathan
AIM/BACKGROUND: Medicinal plants have ability to resist microorganisms by synthesizing secondary metabolites such as phenols. Rosmarinic acid (RA) is a phenylpropanoid widely distributed in plants and well known as therapeutic and cosmetic agent. Methicillin-resistant Staphylococcus aureus (MRSA) which is resistant to all kinds of β-lactams, threatens even most potent antibiotics. To improve the efficiency of antibiotics against multi-drug resistant bacteria and to reduce the antibiotic dose, the antibacterial activity and the synergistic effect of RA with standard antibiotics against S...
September 2016: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/27757264/hematological-changes-and-nitric-oxide-levels-accompanying-high-dose-artemether-lumefantrine-administration-in-male-guinea-pigs-effect-of-unsweetened-natural-cocoa-powder
#14
Isaac Julius Asiedu-Gyekye, Charles Antwi-Boasiako, Seth Oppong, Stella Arthur, Joseph Edusei Sarkodie
BACKGROUND: Unsweetened natural cocoa powder (UNCP), prepared after removal of the cocoa butter, is a common beverage in Ghana. It possesses antimalarial prophylactic property and has a beneficial effect on blood components. AIM: The aim of this study was to determine whether regular dietary supplement of UNCP mitigates high-dose (HD) artemether-lumefantrine (A-L)-induced hematological disorders and to determine the effect on nitric oxide (NO) levels. MATERIALS AND METHODS: Adult male guinea pigs (300 g - 350 g) were randomly divided into 5 groups of 6 guinea pigs each...
September 2016: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/27757263/in-vitro-xanthine-oxidase-and-albumin-denaturation-inhibition-assay-of-barringtonia-racemosa-l-and-total-phenolic-content-analysis-for-potential-anti-inflammatory-use-in-gouty-arthritis
#15
Nurul Izzati Osman, Norrizah Jaafar Sidik, Asmah Awal, Nurul Athirah Mohamad Adam, Nur Inani Rezali
AIM: This study was conducted to evaluate the in vitro anti-inflammatory activities and total phenolic content (TPC) of methanolic extracts of infloresence axes, endosperms, leaves, and pericarps of Barringtonia racemosa L. METHODS: The anti-inflammatory study was conducted by assessing the potential through xanthine oxidase (XO) and albumin denaturation inhibition assays. Meanwhile, the TPC in the extracts were assessed by Folin-Ciocalteu assay. RESULTS: In the XO inhibition assay, the infloresence axes extract was found to exert the highest inhibition capacity at 0...
September 2016: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/27757262/treatment-of-hemorrhoids-with-individualized-homeopathy-an-open-observational-pilot-study
#16
Kaushik Deb Das, Shubhamoy Ghosh, Asim Kumar Das, Aloke Ghosh, Ramkumar Mondal, Tanapa Banerjee, Seikh Sajid Ali, Seikh Swaif Ali, Munmun Koley, Subhranil Saha
AIM: Controversies and disagreement exist on conventional treatment strategies of hemorrhoids due to relapse, inefficacy, and complications. We intend to evaluate the role of individualized homeopathic treatment in hemorrhoids. MATERIALS AND METHODS: In this prospective, open, observational trial, hemorrhoids patients were treated using five standardized scales measuring complaints severity and anoscopic score. It was conducted at two homeopathic hospitals in India, during from mid-July 2014 to mid-July 2015...
September 2016: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/27757261/dna-protective-effect-of-ginseng-and-the-antagonistic-effect-of-chinese-turnip-a-supplementation-study
#17
Yim Tong Szeto, Kam Shing Wong, Andrea Han, Sok Cheon Pak, Wouter Kalle
AIM: The aim of this clinical study is to provide scientific evidence for supporting traditional Chinese application and usage to the patients. For this purpose, we tested the ability if Panax ginseng extract to lower oxidative damage to nuclear DNA in human lymphocytes by comparing the effect of cooked Chinese turnip on this effect. MATERIALS AND METHODS: Seven healthy subjects (4 males and 3 females from 37 to 60 years) participated two occasions which were at least 2 weeks apart...
September 2016: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/27757260/medicinal-plants-used-by-traditional-healers-from-south-west-algeria-an-ethnobotanical-study
#18
Bachir Benarba
BACKGROUND/AIM: This study aimed to document and analyzes the local knowledge of medicinal plants' use by traditional healers in South-west Algeria. METHODS: The ethnobotanical survey was conducted in two Saharian regions of South-west of Algeria: Adrar and Bechar. In total, 22 local traditional healers were interviewed using semi-structured questionnaire and open questions. Use value (UV), fidelity level (FL), and informant consensus factor (FIC) were used to analyze the obtained data...
September 2016: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/27366359/on-the-use-of-carnosine-and-antioxidants-a-letter-from-russia
#19
Sergei V Jargin
No abstract text is available yet for this article.
June 2016: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/27366358/trends-and-challenges-toward-integration-of-traditional-medicine-in-formal-health-care-system-historical-perspectives-and-appraisal-of-education-curricula-in-sub-sahara-africa
#20
REVIEW
Ester Innocent
The population residing Sub-Sahara Africa (SSA) continues to suffer from communicable health problems such as HIV/AIDS, malaria, tuberculosis, and various neglected tropical as well as non-communicable diseases. The disease burden is aggravated by shortage of medical personnel and medical supplies such as medical devices and minimal access to essential medicine. For long time, human beings through observation and practical experiences learned to use different plant species that led to the emergence of traditional medicine (TM) systems...
June 2016: Journal of Intercultural Ethnopharmacology
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