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Journal of Intercultural Ethnopharmacology

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https://www.readbyqxmd.com/read/28163971/solving-the-puzzle-what-is-behind-our-forefathers-anti-inflammatory-remedies
#1
REVIEW
Javier Rodriguez Villanueva, Jorge Martín Esteban, Laura Rodríguez Villanueva
Inflammation is a ubiquitous host response in charge of restoring normal tissue structure and function but is a double-edged sword, as the uncontrolled or excessive process can lead to the injury of host cells, chronic inflammation, chronic diseases, and also neoplastic transformation. Throughout history, a wide range of species has been claimed to have anti-inflammatory effects worldwide. Among them, Angelica sinensis, Tropaeolum majus, Castilleja tenuiflora, Biophytum umbraculum, to name just a few, have attracted the scientific and general public attention in the last years...
January 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28163970/garcinia-subelliptica-merr-fukugi-a-multipurpose-coastal-tree-with-promising-medicinal-properties
#2
REVIEW
Tomomi Inoue, Mami Kainuma, Karin Baba, Nozomi Oshiro, Norimi Kimura, Eric Wei Chiang Chan
In this short review, the current knowledge on the botany, ecology, uses, and medicinal properties of the multipurpose Garcinia subelliptica (Fukugi) is updated. As yet, there are no reviews on this indigenous and heritage coastal tree species of the Ryukyu Islands in Japan, which has ethnocultural, ecological, and pharmacological significance. Planted by the Okinawan people some 300 years ago, Fukugi trees serve as windbreaks and accord protection against the destructive typhoons. The species has become a popular ornamental tree, and its bark has been used for dyeing fabrics...
January 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28163969/assessment-of-in-vitro-cholinesterase-inhibitory-and-thrombolytic-potential-of-bark-and-seed-extracts-of-tamarindus-indica-l-relevant-to-the-treatment-of-alzheimer-s-disease-and-clotting-disorders
#3
Kushal Biswas, A K Azad, Taposhi Sultana, Farzana Khan, Saiyara Hossain, Sanzida Alam, Rayhan Chowdhary, Yasmin Khatun
BACKGROUND: Low level of acetylcholine (ACh) is an important hallmark of Alzheimer's disease (AD), a common type of progressive neurodegenerative disorder. Effective treatment strategies rely mostly on either enhancing the cholinergic function of the brain by improving the level of ACh from being a breakdown by cholinesterase enzymes. Again atherothrombosis is major life-threatening cerebral diseases. Traditionally Tamarindus indica (L.) has widely known for its medicinal values. Our aim is to investigate the cholinesterase inhibitory activities as well as thrombolytic activities of the bark and seeds crude methanolic extracts (CMEs) in the treatment of AD and clotting disorder...
January 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28163968/antioxidant-activity-phenolic-flavonoid-content-and-high-performance-liquid-chromatography-profiling-of-three-different-variants-of-syzygium-cumini-seeds-a-comparative-study
#4
Syama Hari Priya, Nisha Prakasan, Jayamurthy Purushothaman
BACKGROUND: The medicinally important phytochemicals present in Syzygium cumini seeds probably accounts for its wide use in traditional systems of medicines in India, like Ayurveda, Unani, and Siddha. AIM: The aim of the study was to determine the antioxidant potential of three different geographical variants of S. cumini seeds and to compare the phenolic profiling to know the effect of geographical variation in phenolic composition. MATERIALS AND METHODS: Total phenolic and flavonoid content of S...
January 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28163967/pregnancy-detecting-plants-used-in-remo-and-ijebu-areas-of-ogun-state-nigeria
#5
Adediwura Fred-Jaiyesimi, Jolaade Taiwo
AIM/BACKGROUND: Plants and plants extracts are employed in cultures for religious purposes, as beauty therapies, in the detection and management/treatment of diseases. MATERIALS AND METHODOLOGY: In this study, an ethnobotanical studies of plants used in detecting pregnancy in Ijebu and Remo areas of Ogun State were carried out using semi-structured to obtain demographic data, local names of plants, the morphological parts used. Furthermore, a phytochemical analysis of two of the identified plants was performed...
January 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28163966/an-active-principle-of-nigella-sativa-l-thymoquinone-showing-significant-antimicrobial-activity-against-anaerobic-bacteria
#6
Mohammad Akram Randhawa, Awwad Khalaf Alenazy, Majed Gorayan Alrowaili, Jamith Basha
AIM/BACKGROUND: Thymoquinone (TQ) is the major active principle of Nigella sativa seed (black seed) and is known to control many fungi, bacteria, and some viruses. However, the activity of TQ against anaerobic bacteria is not well demonstrated. Anaerobic bacteria can cause severe infections, including diarrhea, aspiration pneumonia, and brain abscess, particularly in immunodeficient individuals. The present study aimed to investigate the in vitro antimicrobial activity of TQ against some anaerobic pathogens in comparison to metronidazole...
January 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28163965/ethnobotanical-survey-and-toxicity-evaluation-of-medicinal-plants-used-for-fungal-remedy-in-the-southern-highlands-of-tanzania
#7
Mourice Victor Nyangabo Mbunde, Ester Innocent, Faith Mabiki, Pher G Andersson
BACKGROUND/AIM: Some of the antifungal drugs used in the current treatments regime are responding to antimicrobial resistance. In rural areas of Southern Tanzania, indigenous people use antifungal drugs alone or together with medicinal plants to curb the effects of antibiotic resistance. This study documented ethnobotanical information of medicinal plants used for managing fungal infections in the Southern Highlands of Tanzania and further assess their safety. MATERIALS AND METHODS: Ethnobotanical survey was conducted in Makete and Mufindi districts between July 2014 and December 2015 using semi-structured questionnaires followed by two focus group discussions to verify respondents' information...
January 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28163964/ethnomedical-survey-and-safety-evaluation-of-traditional-eye-medicines-used-in-misungwi-district-tanzania
#8
Sheila M Maregesi, Charles W Messo, Juma Mathias
AIM: This study aimed at documenting products used as traditional eye medicine (TEM) in Misungwi district, Tanzania, and performing preliminary analysis on safety status. METHODOLOGY: Ethnomedical study was conducted in Misungwi district. Information was sourced by face-to-face interview with traditional healers, traditional medicine vendors, and knowledgeable people guided by a well-structured questionnaire. Safety was evaluated by determining pH using pH meter and mineral analysis using the Delta, Portable X-ray fluorescence equipment, and qualitative chemical tests...
January 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28163963/evaluation-of-the-potential-effect-of-allium-sativum-momordica-charantia-eugenia-jambolana-ocimum-sanctum-and-psidium-guajava-on-intestinal-p-glycoprotein-in-rats
#9
Devendra Kumar, Neerja Trivedi, Rakesh K Dixit
AIMS/BACKGROUND: This study was evaluated synergistic effect of a polyherbal formulation (PHF) of Allium sativum L., Eugenia jambolana Lam., Momordica charantia L., Ocimum sanctum Linn., and Psidium guajava L. on p-glycoprotein (Pgp) of intestine. These five herbs were traditionally used for diabetes. These herbs are commonly present in Ayurvedic product as antidiabetics in India. MATERIALS AND METHODS: PHF was prepared by five indigenous herbs. Different doses (50, 100 and 200 mg/kg/day) of were orally administered to Sprague-Dawley rats of different groups for multiple weeks except control groups...
January 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28163962/high-dose-of-green-tea-infusion-normalized-spiral-artery-density-in-rats-treated-with-the-depot-medroxyprogesterone-acetate
#10
A S Emilda, Nora Veri, Alchalidi Alchalidi
AIM: The purpose of this study was to investigate the effects of green tea (GT) on the spiral artery density and endometrial thickness in female rats treated with the depot-medroxyprogesterone acetate (DMPA). MATERIAL AND METHODS: A total of 24 female rats were randomly divided into four groups (n = 6 each): The control group (no treatment), the DMPA-treated group, treated with DMPA and GT doses of 165 mg/kg of body weight/day, and treated with DMPA and GT doses of 330 mg/kg of body weight/day...
January 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28163961/the-adjuvant-use-of-calcium-fructoborate-and-borax-with-etanercept-in-patients-with-rheumatoid-arthritis-pilot-study
#11
Saad Abdulrahman Hussain, Sattar Jabir Abood, Faiq Isho Gorial
OBJECTIVE: This study was designed to evaluate the effects calcium fructoborate (CFB) and sodium tetraborate (NTB) as supplements in Iraqi patients with active rheumatoid arthritis (RA) maintained on etanercept. MATERIALS AND METHODS: A double-blind randomized placebo-controlled clinical trial with 60 days treatment period was carried out at Baghdad Teaching Hospital, Medical city, Baghdad, Iraq. Eighty RA patients were randomized into three groups to receive either 220 mg/day CFB, 55 mg/day NTB in capsule dosage form (equivalent to 6 mg elemental Boron), or placebo formula once daily...
January 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28163960/screening-for-antibacterial-and-antibiofilm-activities-in-astragalus-angulosus
#12
Hussein Kanaan, Majid El-Mestrah, Alaa Sweidan, Falah As-Sadi, Ali Al Bazzal, Ali Chokr
AIM: In a search for finding novel therapeutic agents, extracts from an endemic Lebanese plant, Astragalus angulosus, were evaluated for their potential in-vitro antibacterial and antibiofilm activities against three Gram-positive bacterial strains; Staphylococcus epidermidis (CIP444), Staphylococcus aureus (ATCC25923), and Enterococcus faecalis (ATCC29212); in addition to two Gram-negative strains, Escherichia coli (ATCC35218) and Pseudomonas aeruginosa (ATCC27853). MATERIALS AND METHODS: The plant was collected in April of 2013 and divided into several different portions, then its extracts were obtained by maceration using two different solvents...
January 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28163959/kolaviron-a-biflavonoid-of-garcinia-kola-seed-mitigates-ischemic-reperfusion-injury-by-modulation-of-pro-survival-and-apoptotic-signaling-pathways
#13
Ademola Adetokunbo Oyagbemi, Dirk Bester, Johan Esterhuyse, Ebenezer Olatunde Farombi
OBJECTIVE: The study was designed to investigate the ameliorative effect of Kolaviron (KV) on ischemic/reperfusion injury in experimental animal models. MATERIALS AND METHODS: Male Wistar rats were randomly divided into two groups: Group 1 received corn oil as a vehicle and rats in Group 2 were administered KV at 200 mg/kg for 4 weeks. The rats were fed with rat standard chow pellet and water administered ad libitum. After 4 weeks of KV administration, hearts were excised and mounted on the working heart perfusion system...
January 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28163958/a-prospective-comparative-field-study-to-evaluate-the-efficacy-of-a-traditional-plant-based-malaria-prophylaxis
#14
Prakash Bangalore Nagendrappa, Pradeep Annamalai, Muruli Naik, Vinay Mahajan, Ashwini Mathur, Ghosh Susanta, Frederick Gay, Padma Venkatasubramanian
BACKGROUND: An unceasing threat of resistance of malarial parasites to available antimalarial drugs makes the development of new drugs imperative. Natural plant-based products are an alternative source for discovering new antimalarial drugs. AIM: To determine the prophylactic efficacy of a traditionally used plant-based drug on prevention of malaria in endemic villages of Odisha, India. METHODS: A total of 267 healthy human volunteers of both sexes, aged 18-60 years were enrolled in Odisha, India, to receive either minimum 20 doses of aqueous extract of Traditional Plant-based Malaria Prophylactic drug 74, twice a week (experimental group), or no drug (control group) for 14 weeks...
January 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28163957/geraniol-attenuates-hydrogen-peroxide-induced-liver-fatty-acid-alterations-in-male-rats
#15
Ahmet Ozkaya, Zafer Sahin, Ahmet Orhan Gorgulu, Abdurrauf Yuce, Sait Celik
BACKGROUND: Hydrogen peroxide (H2O2) is an oxidant agent and this molecule naturally occurs in the body as a product of aerobic metabolism. Geraniol is a plant-derived natural antioxidant. The aim of this study was to determine the role of geraniol on hepatic fatty acids alterations following H2O2-induced oxidative stress in male rats. METHODS: After randomization, male Wistar rats were divided into four groups (n = 7 each group). Geraniol (50 mg/kg, dissolved in corn oil) and H2O2 (16 mg/kg, dissolved in distilled water) were administered by an intraperitoneal injection...
January 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28163956/ocimum-basilicum-extract-exhibits-antidiabetic-effects-via-inhibition-of-hepatic-glucose-mobilization-and-carbohydrate-metabolizing-enzymes
#16
Chinelo Ezeani, Ifeoma Ezenyi, Theophine Okoye, Charles Okoli
AIM: Ocimum basilicum L (Lamiaceae) is used as a traditional remedy for different ailments, including diabetes mellitus. This study investigated the antidiabetic effects of an extract of aerial parts of O. basilicum. METHODS: Antihyperglycemic effect of the extract was determined by its effects on α-amylase and α-glucosidase in vitro, while antidiabetic properties were studied in alloxan induced diabetic rats treated for 28 days with extract and compared to those treated with oral metformin (150 mg/kg)...
January 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28163955/antinociceptive-and-anti-inflammatory-effects-of-aqueous-extract-of-chenopodium-opulifolium-schrad-leaves
#17
Abayomi M Ajayi, Julius Khidzee Tanayen, Albert Magomere, Joseph O C Ezeonwumelu
AIM: Chenopodium opulifolium is a specie of the Chenopodiaceae commonly used as vegetables in local diet and for treating different ailment in Uganda. This study was conducted to evaluate the antioxidant, antinociceptive and anti-inflammatory effects of the aqueous extract of C. opulifolium leaves (AECO). MATERIALS AND METHODS: The dried leaf of the plant was extracted by maceration in water. Qualitative and quantitative phytochemical analysis, antioxidants, and membrane stabilizing effects were determined in the extract...
January 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28163954/effect-of-nigella-sativa-black-seeds-against-methotrexate-induced-nephrotoxicity-in-mice
#18
Jawad Hassan Ahmed, Isra Mohammed Abdulmajeed
AIM: To evaluate the protective effect of Nigella sativa (NS) against nephrotoxicity of methotrexate (MTX) in mice. MATERIALS AND METHODS: Four groups of Swiss albino male mice, eight in each group were used. The study was carried on between October 2014 and April 2015. Group 1 (control) were administered 0.3 ml distilled water orally daily for 21 days and injected with normal saline (0.25 ml) IP weekly. Group 2 (MTX group) were treated with MTX, 10 mg/kg IP weekly, while Group 3 were treated with 0...
January 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28163953/is-there-a-role-for-homeopathy-in-breast-cancer-surgery-a-first-randomized-clinical-trial-on-treatment-with-arnica-montana-to-reduce-post-operative-seroma-and-bleeding-in-patients-undergoing-total-mastectomy
#19
Luca Sorrentino, Salvatore Piraneo, Eliana Riggio, Silvia Basilicò, Alessandra Sartani, Daniela Bossi, Fabio Corsi
AIM: This study aimed to evaluate the benefits of Arnica montana on post-operative blood loss and seroma production in women undergoing unilateral total mastectomy by administering Arnica Montana 1000 Korsakovian dilution (1000 K). MATERIALS AND METHODS: From 2012 to 2014, 53 women were randomly assigned to A. montana or placebo and were followed up for 5 days. The main end point was the reduction in blood and serum volumes collected in drainages. Secondary end points were duration of drainage, a self-evaluation of pain, and the presence of bruising or hematomas...
January 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/27757277/effects-of-a-diet-containing-brazilian-propolis-on-lipopolysaccharide-induced-increases-in-plasma-plasminogen-activator-inhibitor-1-levels-in-mice
#20
Naoki Ohkura, Katsutaka Oishi, Fumiko Kihara-Negishi, Gen-Ichi Atsumi, Tomoki Tatefuji
BACKGROUND: Brazilian propolis has many biological activities including the ability to help prevent thrombotic diseases, but this particular effect has not been proven. Plasma levels of plasminogen activator inhibitor-1 (PAI-1), an inhibitor of fibrinolysis, increase under inflammatory conditions such as infection, obesity and atherosclerosis and such elevated levels predispose individuals to a risk of developing thrombotic diseases. AIM: This study aimed to determine the effects of a diet containing Brazilian propolis on lipopolysaccharide (LPS)-induced increases in plasma PAI-1 levels...
September 2016: Journal of Intercultural Ethnopharmacology
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