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Journal of Intercultural Ethnopharmacology

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https://www.readbyqxmd.com/read/28512606/antimicrobial-activity-of-nigerian-medicinal-plants
#1
REVIEW
Madubuike Umunna Anyanwu, Rosemary Chinazam Okoye
Antimicrobial resistance (AMR) is currently one of the major threats facing mankind. The emergence and rapid spread of multi- and pan-drug-resistant organisms (such as vancomycin-, methicillin-, extended-spectrum β-lactam-, carbapenem- and colistin-resistant organisms) has put the world in a dilemma. The health and economic burden associated with AMR on a global scale are dreadful. Available antimicrobials have been misused and are almost ineffective with some of these drugs associated with dangerous side effects in some individuals...
April 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28512605/toxicity-status-and-antiulcerative-potential-of-sansevieria-trifasciata-leaf-extract-in-wistar-rats
#2
Osasenaga Macdonald Ighodaro, Abiola Muhammad Adeosun, Barinemene Francis Ojiko, Abeeb Taiwo Akorede, Oyindamola Fuyi-Williams
AIMS: The lethal dose 50% (LD50) and antiulcerative potentials of Sansevieria trifasciata (ST) leaf extract were investigated. MATERIALS AND METHODS: LD50 was determined through two routes of administration (intraperitoneal [i.p] and oral [p.o]) using the method of Lorke. The antiulcerative activity was evaluated in indomethacin-induced ulcer model (40 mg/kg body weight [BW], i.p, single dose) against a reference drug, cimetidine (100 mg/kg BW, p.o). ST was assessed at two different doses (200 and 400 mg/kg BW, p...
April 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28512604/traditional-dentistry-knowledge-among-serbs-in-several-balkan-countries
#3
Dragan V Ilic, Biljana Andjelski Radicevic, Anely Nedelcheva, Ivana Djurovic, Dejan Ostojic
BACKGROUND/AIM: There are still unrevealed treasures of traditional dental medicine, that is, the reason to investigate and present various ways in treatment of oral and orofacial tissues, as well as magic and religious elements involved in representative areas among Serbs. MATERIALS AND METHODS: Information was collected from the elderly non-professional folk dentists and herbalists with the additional help of local physicians and dentists that was done through questionnaire and personal interviews...
April 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28512603/bactericidal-activity-of-herbal-volatile-oil-extracts-against-multidrug-resistant-acinetobacter-baumannii
#4
Amornrat Intorasoot, Piyaorn Chornchoem, Siriwoot Sookkhee, Sorasak Intorasoot
AIM: The aim of the study is to investigate the antibacterial activity of 10 volatile oils extracted from medicinal plants, including galangal (Alpinia galanga Linn.), ginger (Zingiber officinale), plai (Zingiber cassumunar Roxb.), lime (Citrus aurantifolia), kaffir lime (Citrus hystrix DC.), sweet basil (Ocimum basilicum Linn.), tree basil (Ocimum gratissimum), lemongrass (Cymbopogon citratus DC.), clove (Syzygium aromaticum), and cinnamon (Cinnamomum verum) against four standard strains of Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Acinetobacter baumannii, and 30 clinical isolates of multidrug-resistant A...
April 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28512602/bio-efficacy-of-medicinal-plants-used-for-the-management-of-diabetes-mellitus-in-gabon-an-ethnopharmacological-approach
#5
Olga Pauline Tjeck, Alain Souza, Patrick Mickala, Alexis Nicaise Lepengue, Bertrand M'Batchi
BACKGROUND/AIM: People suffering of diabetes increased significantly worldwide. Population, in Sub-Saharan Africa and mainly in Gabon, rely on medicinal plants to manage diabetes, as well in rural as in urban areas. This study aimed to survey a wide range of Gabonese plants for their antidiabetic activity. MATERIALS AND METHODS: This study focused on the identification of medicinal plants used in the local treatment of diabetes mellitus. Ethnobotanical investigations were carried out in rural and urban areas of three provinces of Gabon using a semi-structured interview...
April 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28512601/anti-nociceptive-and-anti-inflammatory-potentials-of-vernoniaamygdalina-leaf-extract-via-reductions-of-leucocyte-migration-and-lipid-peroxidation
#6
Samuel Adetunji Onasanwo, Oyetola Tolulope Oyebanjo, Abayomi Mayowa Ajayi, Mujeedat Adebukola Olubori
BACKGROUND: Vernonia amygdalina is well known as a medicinal plant in folk medicine as antidiabetic, anthelmintic, antimalarial, laxative/purgative, and expectorant among others. AIM: This study was conducted to investigate the antinociceptive and anti-inflammatory effects of V. amygdalina. MATERIALS AND METHODS: Methanol extract of V. amygdalina leaf (MEVA) was evaluated for antinociceptive effect and possible mechanisms of action in the presence of naloxone (1 mg/kg), atropine (2 mg/kg), and prazosin (1 mg/kg) using acetic acid writhing test in mice...
April 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28512600/a-synergistic-effect-of-artocarpanone-from-artocarpus-heterophyllus-l-moraceae-on-the-antibacterial-activity-of-selected-antibiotics-and-cell-membrane-permeability
#7
Abdi Wira Septama, Jianbo Xiao, Pharkphoom Panichayupakaranant
AIM/BACKGROUNDS: Artocarpanone isolated from Artocarpus heterophyllus L. (Moraceae) exhibits antibacterial activity. The present study investigated synergistic activity between artocarpanone and tetracycline, ampicillin, and norfloxacin, respectively, against methicillin-resistant Staphylococcus aureus (MRSA), Pseudomonas aeruginosa, and Escherichia coli. MATERIALS AND METHODS: A broth microdilution method was used for evaluating antibacterial susceptibility. Synergistic effects were identified using a checkerboard method, and a bacterial cell membrane disruption was investigated by assay of released 260 nm absorbing materials following bacteriolysis...
April 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28512599/effect-of-trichilia-monadelpha-meliaceae-extracts-on-bone-histomorphology-in-complete-freund-s-adjuvant-induced-arthritis
#8
Inemesit Okon Ben, Eric Woode, George Asumeng Koffuor, Eric Boakye-Gyasi, Nicholas Akinwale Titiloye
AIM: This study aimed to assess the effect of petroleum ether extract (PEE), ethyl acetate extract (EthE), and ethanol extract (EAE) of Trichilia monadelpha stem bark on bone histomorphology in arthritis. METHODS: Percentage inhibition of edema and arthritic scores in complete Freund's adjuvant-induced (0.1 ml of 5 mg/ml(1) of heat-killed Mycobacterium tuberculosis in paraffin oil-injected subplantar into the right hind paw) arthritic Sprague-Dawley rats treated with PEE, EthE, or EAE (10,30, and 100 mg/kg(1), respectively), dexamethasone (0...
April 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28512598/phytochemical-screening-and-study-of-antioxidant-antimicrobial-antidiabetic-anti-inflammatory-and-analgesic-activities-of-extracts-from-stem-wood-of-pterocarpus-marsupium-roxburgh
#9
Dipak Raj Pant, Narayan Dutt Pant, Dil Bahadur Saru, Uday Narayan Yadav, Dharma Prasad Khanal
AIMS: The main aims of the study were to evaluate the phytochemical constituents and to study the antioxidant, antimicrobial, antidiabetic, anti-inflammatory, and analgesic activities of extracts from stem wood of Pterocarpus marsupium. MATERIALS AND METHODS: Ethanol, acetone and isopropyl alcohol (IPA) (1:1) extracts of stem wood of P. marsupium were subjected to phytochemical screening and analysis of biological activities from August 2015 to January 2016. The antioxidant assay was carried out using 2, 2-diphenyl-1-picrylhydrazyl scavenging method, antimicrobial activity testing by cup diffusion method, antidiabetic test evaluation by oral glucose tolerance test in mice, anti-inflammatory effect was evaluated by hind paw edema method in mice and analgesic test evaluation by a chemical writhing method in mice...
April 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28512597/documentation-of-ethnomedicinal-information-and-antimicrobial-validation-of-thespesia-populnea-used-by-yanadi-tribe-of-ganugapenta-village-chittoor-district-andhra-pradesh-india
#10
Nataru Savithramma, Pulicherla Yugandhar, Pallipati Suvarnalatha Devi, Sade Ankanna, Damai Suhrulatha, Koya Siva Prasad, Ramakrishanan Ranjani, Nagoji Nagaraju, Kummara Madhava Chetty
AIM: This study aimed to document the traditional knowledge of medicinal plants and antimicrobial validation of Thespesia populnea used by Yanadi tribe of Chittoor district, Andhra Pradesh, India. MATERIALS AND METHODS: The study was mainly focused on documentation of medicinal plants used by Yanadi tribe to treat different diseases with a standard questionnaire. These plants were cross-checked in Dr. Dukes Database and available literature to know the significance of this tribe on medicinal knowledge...
April 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28512596/in-vitro-screening-for-protein-tyrosine-phosphatase-1b-and-dipeptidyl-peptidase-iv-inhibitors-from-selected-nigerian-medicinal-plants
#11
Yusuf Saidu, Suleiman Alhaji Muhammad, Abdullahi Yahaya Abbas, Andrew Onu, Ibrahim Mohammed Tsado, Luba Muhammad
BACKGROUND/AIM: Protein tyrosine phosphatase 1B (PTP 1B) and dipeptidyl peptidase IV (DPP IV) have been identified as one of the drug targets for the treatment of Type-2 diabetes. This study was designed to screen for PTP 1B and DPP-IV inhibitors from some Nigerian medicinal plants. MATERIALS AND METHODS: PTP 1B and DPP-IV drug discovery kits from Enzo Life Sciences were used to investigate in vitro inhibitory effect of crude methanolic extract of 10 plants; Mangifera indica, Moringa oleifera, Acacia nilotica, Arachis hypogaea, Senna nigricans, Azadirachta indica, Calotropis procera, Leptadenia hastata, Ziziphus mauritiana, and Solanum incanum...
April 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28512595/reassessment-of-the-polar-fraction-of-stachys-alopecuros-l-benth-subsp-divulsa-ten-grande-lamiaceae-from-the-monti-sibillini-national-park-a-potential-source-of-bioactive-compounds
#12
Alessandro Venditti, Claudio Frezza, Lorenzo M Lorenzetti, Filippo Maggi, Mauro Serafini, Armandodoriano Bianco
BACKGROUND: The phytochemical analysis of Stachys alopecuros subsp. divulsa, an endemic Italian species, has been recently reported and has showed the presence of 8-O-acetylharpagide (2), harpagide (3), allobetonicoside (4), and 4¢-O-galactopyranosyl-teuhircoside (5). In this paper, an in deep study of its glycosidic fraction with the aim to widen the knowledge on its secondary metabolites content is reported. MATERIALS AND METHODS: Chromatographic techniques were used for the isolation of constituents while spectroscopic and spectrometric techniques were applied for the structures elucidation...
April 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28507784/geraniin-attenuates-naloxone-precipitated-morphine-withdrawal-and-morphine-induced-tolerance-in-mice
#13
Ella Anle Kasanga, Eric Boakye-Gyasi, Robert Peter Biney, James Oppong Kyekyeku, Christian Agyare, Eric Woode
BACKGROUND AND AIM: Potentially life-threatening and unpleasant side effects associated with some analgesics have fueled the drive for the search for more analgesics with better side effect profiles. Geraniin, the most dominant secondary metabolite in the aqueous extract of the aerial parts of Phyllanthus muellerianus, has been shown to possess antinociceptive properties mediated partly by opioidergic mechanisms. The purpose of this study is to determine whether geraniin exhibits tolerance and if it is able to ameliorate withdrawal signs in naloxone-precipitated morphine withdrawal...
April 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28163971/solving-the-puzzle-what-is-behind-our-forefathers-anti-inflammatory-remedies
#14
REVIEW
Javier Rodriguez Villanueva, Jorge Martín Esteban, Laura Rodríguez Villanueva
Inflammation is a ubiquitous host response in charge of restoring normal tissue structure and function but is a double-edged sword, as the uncontrolled or excessive process can lead to the injury of host cells, chronic inflammation, chronic diseases, and also neoplastic transformation. Throughout history, a wide range of species has been claimed to have anti-inflammatory effects worldwide. Among them, Angelica sinensis, Tropaeolum majus, Castilleja tenuiflora, Biophytum umbraculum, to name just a few, have attracted the scientific and general public attention in the last years...
January 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28163970/garcinia-subelliptica-merr-fukugi-a-multipurpose-coastal-tree-with-promising-medicinal-properties
#15
REVIEW
Tomomi Inoue, Mami Kainuma, Karin Baba, Nozomi Oshiro, Norimi Kimura, Eric Wei Chiang Chan
In this short review, the current knowledge on the botany, ecology, uses, and medicinal properties of the multipurpose Garcinia subelliptica (Fukugi) is updated. As yet, there are no reviews on this indigenous and heritage coastal tree species of the Ryukyu Islands in Japan, which has ethnocultural, ecological, and pharmacological significance. Planted by the Okinawan people some 300 years ago, Fukugi trees serve as windbreaks and accord protection against the destructive typhoons. The species has become a popular ornamental tree, and its bark has been used for dyeing fabrics...
January 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28163969/assessment-of-in-vitro-cholinesterase-inhibitory-and-thrombolytic-potential-of-bark-and-seed-extracts-of-tamarindus-indica-l-relevant-to-the-treatment-of-alzheimer-s-disease-and-clotting-disorders
#16
Kushal Biswas, A K Azad, Taposhi Sultana, Farzana Khan, Saiyara Hossain, Sanzida Alam, Rayhan Chowdhary, Yasmin Khatun
BACKGROUND: Low level of acetylcholine (ACh) is an important hallmark of Alzheimer's disease (AD), a common type of progressive neurodegenerative disorder. Effective treatment strategies rely mostly on either enhancing the cholinergic function of the brain by improving the level of ACh from being a breakdown by cholinesterase enzymes. Again atherothrombosis is major life-threatening cerebral diseases. Traditionally Tamarindus indica (L.) has widely known for its medicinal values. Our aim is to investigate the cholinesterase inhibitory activities as well as thrombolytic activities of the bark and seeds crude methanolic extracts (CMEs) in the treatment of AD and clotting disorder...
January 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28163968/antioxidant-activity-phenolic-flavonoid-content-and-high-performance-liquid-chromatography-profiling-of-three-different-variants-of-syzygium-cumini-seeds-a-comparative-study
#17
Syama Hari Priya, Nisha Prakasan, Jayamurthy Purushothaman
BACKGROUND: The medicinally important phytochemicals present in Syzygium cumini seeds probably accounts for its wide use in traditional systems of medicines in India, like Ayurveda, Unani, and Siddha. AIM: The aim of the study was to determine the antioxidant potential of three different geographical variants of S. cumini seeds and to compare the phenolic profiling to know the effect of geographical variation in phenolic composition. MATERIALS AND METHODS: Total phenolic and flavonoid content of S...
January 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28163967/pregnancy-detecting-plants-used-in-remo-and-ijebu-areas-of-ogun-state-nigeria
#18
Adediwura Fred-Jaiyesimi, Jolaade Taiwo
AIM/BACKGROUND: Plants and plants extracts are employed in cultures for religious purposes, as beauty therapies, in the detection and management/treatment of diseases. MATERIALS AND METHODOLOGY: In this study, an ethnobotanical studies of plants used in detecting pregnancy in Ijebu and Remo areas of Ogun State were carried out using semi-structured to obtain demographic data, local names of plants, the morphological parts used. Furthermore, a phytochemical analysis of two of the identified plants was performed...
January 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28163966/an-active-principle-of-nigella-sativa-l-thymoquinone-showing-significant-antimicrobial-activity-against-anaerobic-bacteria
#19
Mohammad Akram Randhawa, Awwad Khalaf Alenazy, Majed Gorayan Alrowaili, Jamith Basha
AIM/BACKGROUND: Thymoquinone (TQ) is the major active principle of Nigella sativa seed (black seed) and is known to control many fungi, bacteria, and some viruses. However, the activity of TQ against anaerobic bacteria is not well demonstrated. Anaerobic bacteria can cause severe infections, including diarrhea, aspiration pneumonia, and brain abscess, particularly in immunodeficient individuals. The present study aimed to investigate the in vitro antimicrobial activity of TQ against some anaerobic pathogens in comparison to metronidazole...
January 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28163965/ethnobotanical-survey-and-toxicity-evaluation-of-medicinal-plants-used-for-fungal-remedy-in-the-southern-highlands-of-tanzania
#20
Mourice Victor Nyangabo Mbunde, Ester Innocent, Faith Mabiki, Pher G Andersson
BACKGROUND/AIM: Some of the antifungal drugs used in the current treatments regime are responding to antimicrobial resistance. In rural areas of Southern Tanzania, indigenous people use antifungal drugs alone or together with medicinal plants to curb the effects of antibiotic resistance. This study documented ethnobotanical information of medicinal plants used for managing fungal infections in the Southern Highlands of Tanzania and further assess their safety. MATERIALS AND METHODS: Ethnobotanical survey was conducted in Makete and Mufindi districts between July 2014 and December 2015 using semi-structured questionnaires followed by two focus group discussions to verify respondents' information...
January 2017: Journal of Intercultural Ethnopharmacology
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