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Pulse (Basel, Switzerland)

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https://www.readbyqxmd.com/read/27752480/vitamin-k-dependent-protection-of-the-renal-microvasculature-histopathological-studies-in-normal-and-diseased-kidneys
#1
Fang-Fei Wei, Nadja E A Drummen, Lutgarde Thijs, Lotte Jacobs, Marjolein Herfs, Cynthia Van't Hoofd, Cees Vermeer, Jan A Staessen
Vitamin-K-dependent carboxylation of matrix Gla protein (MGP) protects the macrocirculation against calcification. We recently reported in a multiethnic population study that the estimated glomerular filtration rate, a microvascular trait, decreased and the risk of chronic kidney disease increased with higher circulating levels of inactive dephospho-uncarboxylated MGP, a marker of vitamin K deficiency. These findings highlighted the possibility that vitamin K might have a beneficial effect on the renal microcirculation...
September 2016: Pulse (Basel, Switzerland)
https://www.readbyqxmd.com/read/27752479/the-role-of-home-blood-pressure-telemonitoring-for-blood-pressure-control
#2
Chan Joo Lee, Sungha Park
Despite improvements in hypertension awareness and treatment, the blood pressure (BP) control rate still remains at around 50%. One of the major determinants of low BP control results from therapeutic inertia of the physician and suboptimal compliance of the patients. Home BP self-measurement and monitoring improves patients' awareness and helps the management of hypertension. Recent technological advances are allowing for accurate measurement and telemonitoring of home BP, with a number of randomized clinical trials demonstrating the efficacy of telemonitoring for BP control...
September 2016: Pulse (Basel, Switzerland)
https://www.readbyqxmd.com/read/27752478/aortic-stiffness-cerebrovascular-dysfunction-and-memory
#3
Leroy L Cooper, Gary F Mitchell
BACKGROUND: Aortic stiffness is associated with cardiovascular and cerebrovascular events and cognitive decline. This mini-review focuses on relations of aortic stiffness with microvascular dysfunction and discusses the contribution of abnormal pulsatile hemodynamics to cerebrovascular damage and cognitive decline. We also provide a rationale for considering aortic stiffness as a putative and important contributor to memory impairment in older individuals. SUMMARY: Aging is associated with stiffening of the aorta but not the muscular arteries, which reduces wave reflection and increases the transmission of pulsatility into the periphery...
September 2016: Pulse (Basel, Switzerland)
https://www.readbyqxmd.com/read/27752477/relationship-between-interleukin-6-174g-c-and-572c-g-promoter-gene-polymorphisms-and-risk-of-intracerebral-hemorrhage-a-meta-analysis
#4
Pradeep Kumar, Shubham Misra, Arun Kumar Yadav, Amit Kumar, Mukesh Sriwastva, Kameshwar Prasad
BACKGROUND: Polymorphisms of -174G/C and -572C/G in the Interleukin-6 (IL-6) promoter gene can affect both transcription and secretion of IL-6 and may be involved in the inflammatory mechanisms in early and delayed phases after intracerebral hemorrhage (ICH). The role of these polymorphisms remains unclear for the pathogenesis of ICH. METHODS: PubMed, EMBASE, MEDLINE and Google Scholar searches were conducted from January 1, 1950 to February 29, 2016 and were supplemented with relevant articles identified in the references...
September 2016: Pulse (Basel, Switzerland)
https://www.readbyqxmd.com/read/27493904/the-j-curve-phenomenon-in-hypertension
#5
REVIEW
Yuan-Yuan Kang, Ji-Guang Wang
Almost immediately after antihypertensive therapy was proven effective in preventing cardiovascular events, the J-curve issue emerged as a hot topic. The Hypertension Optimal Treatment (HOT) trial attempted to address this question (diastolic blood pressure <80, <85, and <90 mm Hg) but ended up with a post hoc analysis indicating a nadir of 138.5 mm Hg systolic and 82.6 mm Hg diastolic blood pressure. Nevertheless, this observational finding was supported by the results of observational studies in the general population and by post hoc analyses of antihypertensive treatment trials...
July 2016: Pulse (Basel, Switzerland)
https://www.readbyqxmd.com/read/27493903/molecular-mechanisms-of-arterial-stiffening
#6
REVIEW
Marina Cecelja, Phil Chowienczyk
Stiffening of large arteries is a hallmark of vascular aging and one of the most important determinants of the age-related increase in blood pressure and cardiovascular disease events. Despite a substantial genetic component, the molecular mechanisms underlying phenotypic variability in arterial stiffness remain unknown. Previous genetic studies have identified several genetic variants that are associated with measures of arterial stiffness. Here, we review the relevant advances in the identification of pathways underlying arterial stiffness from genomic studies...
July 2016: Pulse (Basel, Switzerland)
https://www.readbyqxmd.com/read/27493902/within-home-blood-pressure-variability-on-a-single-occasion-has-clinical-significance
#7
REVIEW
Seiichi Shibasaki, Satoshi Hoshide, Kazuomi Kario
There is growing evidence that diversely defined blood pressure variability (BPV) is an independent predictor of hypertensive target organ damage (TOD) and cardiovascular events. Several mechanisms have been speculated to underlie episodes of increased BPV, including the impairment of autonomic or hormonal regulation, renal dysfunction, and increased arterial stiffness. Within-home BPV, defined as differences in BP values obtained on a single occasion at home, could have prognostic significance for hypertensive TOD...
July 2016: Pulse (Basel, Switzerland)
https://www.readbyqxmd.com/read/27493901/relation-of-habitual-chocolate-consumption-to-arterial-stiffness-in-a-community-based-sample-preliminary-findings
#8
Georgina E Crichton, Merrill F Elias, Ala'a Alkerwi, Saverio Stranges, Walter P Abhayaratna
BACKGROUND: The consumption of chocolate and cocoa has established cardiovascular benefits. Less is known about the effects of chocolate on arterial stiffness, a marker of subclinical cardiovascular disease. The aim of this study was to investigate whether chocolate intakes are independently associated with pulse wave velocity (PWV), after adjustment for cardiovascular, lifestyle and dietary factors. METHODS: Prospective analyses were undertaken on 508 community-dwelling participants (mean age 61 years, 60% women) from the Maine-Syracuse Longitudinal Study (MSLS)...
July 2016: Pulse (Basel, Switzerland)
https://www.readbyqxmd.com/read/27493900/carotid-stiffness-a-novel-cerebrovascular-disease-risk-factor
#9
REVIEW
Thomas T van Sloten, Coen D A Stehouwer
Carotid stiffening is considered an important element in the pathogenesis of cerebrovascular diseases. These include stroke as well as vascular dementia and depression. However, results of individual studies evaluating the association between carotid stiffening and incident stroke have been inconsistent. Therefore, we have conducted a systematic review and meta-analysis, showing that carotid stiffening is associated with incident stroke independently of cardiovascular risk factors and aortic stiffness. In addition, carotid stiffening improved stroke risk prediction beyond the Framingham stroke risk factors and aortic stiffness...
July 2016: Pulse (Basel, Switzerland)
https://www.readbyqxmd.com/read/27493899/assessment-of-arterial-stiffness-using-the-cardio-ankle-vascular-index
#10
REVIEW
Toru Miyoshi, Hiroshi Ito
BACKGROUND: Arterial stiffness is an independent predictor of outcomes for patients with cardiovascular disease. Although measurement of pulse wave velocity is a widely accepted, noninvasive approach for the assessment of arterial stiffness, its accuracy is affected by changes in blood pressure. SUMMARY: The cardio-ankle vascular index (CAVI) is an index of the overall stiffness of the artery from the origin of the aorta to the ankle and is theoretically independent of blood pressure at the time of measurement...
July 2016: Pulse (Basel, Switzerland)
https://www.readbyqxmd.com/read/27493898/anatomical-and-functional-estimations-of-brachial-artery-diameter-and-elasticity-using-oscillometric-measurements-with-a-quantitative-approach
#11
REVIEW
Keiichiro Yoshinaga, Satoshi Fujii, Yuuki Tomiyama, Keisuke Takeuchi, Nagara Tamaki
Noninvasive vascular function measurement plays an important role in detecting early stages of atherosclerosis and in evaluating therapeutic responses. In this regard, recently, new vascular function measurements have been developed. These new measurements have been used to evaluate vascular function in coronary arteries, large aortic arteries, or peripheral arteries. Increasing vascular diameter represents vascular remodeling related to atherosclerosis. Attenuated vascular elasticity may be a reliable marker for atherosclerotic risk assessment...
July 2016: Pulse (Basel, Switzerland)
https://www.readbyqxmd.com/read/27195246/quantification-of-the-interrelationship-between-brachial-ankle-and-carotid-femoral-pulse-wave-velocity-in-a-workplace-population
#12
Yi-Bang Cheng, Yan Li, Chang-Sheng Sheng, Qi-Fang Huang, Ji-Guang Wang
BACKGROUND: Brachial-ankle pulse wave velocity (PWV) is increasingly used for the measurement of arterial stiffness. In the present study, we quantified the interrelationship between brachial-ankle and carotid-femoral PWV in a workplace population, and investigated the associations with cardiovascular risk factors and carotid intima-media thickness (IMT). METHODS: Brachial-ankle and carotid-femoral PWV were measured using the Omron-Colin VP1000 and SphygmoCor devices, respectively...
April 2016: Pulse (Basel, Switzerland)
https://www.readbyqxmd.com/read/27195245/hyperuricemia-cardiovascular-disease-and-hypertension
#13
REVIEW
Masanari Kuwabara
In recent years, there has been an increase in the prevalence of hyperuricemia, and the latter has attracted attention as an adult lifestyle-associated disease, together with hypertension, diabetes, and dyslipidemia. Although hyperuricemia is known to be an independent risk factor for hypertension, whether it is an independent risk factor for cardiovascular disease remains controversial. Recently, some small-scale interventional studies on antihyperuricemic medications showed that the latter improved angina symptoms and prevented cardiovascular disease...
April 2016: Pulse (Basel, Switzerland)
https://www.readbyqxmd.com/read/27195244/arterial-stiffness-and-chronic-kidney-disease
#14
Anne-Sophie Garnier, Marie Briet
Chronic kidney disease (CKD) is a major public health concern due to the high prevalence of associated cardiovascular (CV) disease. CV mortality is 10-30 times higher in end-stage renal disease patients than in the age-adjusted general population. The last 20 years have been marked by a huge effort in the characterization of the vascular remodeling process associated with CKD and its consequences on the renal, CV and general prognosis. By comparison with patients with normal renal function, with or without hypertension, an increase in large artery stiffness has been described in end-stage renal disease as well as in CKD stages 2-5...
April 2016: Pulse (Basel, Switzerland)
https://www.readbyqxmd.com/read/27195243/association-between-tumor-necrosis-factor-%C3%AE-238g-a-and-308g-a-gene-polymorphisms-and-risk-of-ischemic-stroke-a-meta-analysis
#15
REVIEW
Pradeep Kumar, Shubham Misra, Amit Kumar, Awadh Kishor Pandit, Kamalesh Chakravarty, Kameshwar Prasad
Tumor necrosis factor-α (TNF-α) is a proinflammatory pleiotropic cytokine which may contribute to the initiation and progression of ischemic stroke (IS). Thus far, numerous studies have been performed to examine the association between -238G/A (rs361525) and -308G/A (rs1800629) polymorphisms in the promoter regions of the TNF-α gene and susceptibility to IS, but results are still conflicting. The aim of this meta-analysis is to provide a relatively comprehensive account of the association between TNF-α -238G/A and -308G/A gene polymorphisms and susceptibility to IS...
April 2016: Pulse (Basel, Switzerland)
https://www.readbyqxmd.com/read/27195242/practical-suitability-of-a-stand-alone-oscillometric-central-blood-pressure-monitor-a-review-of-the-microlife-watchbp-office-central
#16
Willem J Verberk, Hao-Min Cheng, Li-Chih Huang, Chia-Ming Lin, Yao-Pin Teng, Chen-Huan Chen
Accumulating evidence indicates that central blood pressure (CBP) is a better cardiovascular risk predictor than brachial blood pressure (BP). Although more additional benefits of CBP-based treatment above usual hypertension treatment are to be demonstrated, the demand for implementing CBP assessment in general clinical practice is increasing. For this, the measurement procedure must be noninvasive, easy to perform, and cost- and time-efficient. Therefore, oscillometric devices with the possibility to assess CBP seem the best option...
April 2016: Pulse (Basel, Switzerland)
https://www.readbyqxmd.com/read/27195241/brachial-ankle-pulse-wave-velocity-background-method-and-clinical-evidence
#17
REVIEW
Masanori Munakata
BACKGROUND: The populations of many developed countries are becoming progressively older. In aged societies, assessment of total vascular risk is critically important, because old age is usually associated with multiple risks. In this regard, pulse wave velocity (PWV) could be a global cardiovascular marker, since it increases with advancing age, high blood pressure, hyperglycaemia, and other traditional risks, summating cardiovascular risks. Carotid-femoral PWV has been widely applied in Western countries and has been used as a gold-standard PWV measure...
April 2016: Pulse (Basel, Switzerland)
https://www.readbyqxmd.com/read/27195240/new-insight-into-effects-of-%C3%AE-blockers-on-arterial-functions
#18
REVIEW
Kazuo Eguchi
The effects of β-blockers on arterial properties are not well investigated. In our recent study, we compared the effects of the two β-blockers celiprolol and bisoprolol on blood pressure, baroreflex sensitivity (BRS), flow-mediated vasodilatation, and vascular stiffness. We found that bisoprolol achieved a greater reduction in the pulse rate and improved BRS and vascular stiffness, whereas celiprolol reduced the central blood pressure level. In this review, the mechanisms of different types of β-blockers and their effects on arteries are discussed, and the appropriate use of β-blockers in hypertensive subjects will be proposed...
April 2016: Pulse (Basel, Switzerland)
https://www.readbyqxmd.com/read/27195239/cerebral-small-vessel-disease-and-arterial-stiffness-tsunami-effect-in-the-brain
#19
REVIEW
Naoki Saji, Kenji Toba, Takashi Sakurai
BACKGROUND: Cerebral small vessel diseases, including silent lacunar infarcts, white matter hyperintensities, and microbleeds, pose a risk for cerebrovascular disease, cognitive impairment, and the geriatric syndrome via effects on arterial stiffness. However, the vascular, physiological, and metabolic roles of arterial stiffness in cerebral small vessel diseases remain unclear. SUMMARY: Arterial stiffness can be assessed using various indicators such as the ankle-brachial index, pulse wave velocity, cardio-ankle vascular index, and augmentation index...
April 2016: Pulse (Basel, Switzerland)
https://www.readbyqxmd.com/read/27195238/comment-on-the-paper-by-cauwenberghs-and-kuznetsova-entitled-determinants-and-prognostic-significance-of-the-renal-resistive-index
#20
Yuhei Kawano, Yoshio Iwashima
No abstract text is available yet for this article.
April 2016: Pulse (Basel, Switzerland)
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