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Przeglad Menopauzalny, Menopause Review

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https://www.readbyqxmd.com/read/30357030/premature-ovarian-insufficiency-hormone-replacement-therapy-and-management-of-long-term-consequences
#1
REVIEW
Paulina Machura, Monika Grymowicz, Ewa Rudnicka, Wojciech Pięta, Anna Calik-Ksepka, Jolanta Skórska, Roman Smolarczyk
Premature ovarian insufficiency (POI) correlates with increased risk of cardiovascular diseases, osteoporosis, genitourinary syndrome, and other symptoms of prolonged oestrogen deprivation. Properly selected therapy improves the quality of women's lives and reduces the risk of mortality. There is a wide spectrum of available oestrogen and progestogen formulations restoring proper levels of serum sex steroid hormones. The treatment should be implemented at recognition of the POI and continued to at least the age of natural menopause...
September 2018: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/30357029/spontaneous-pregnancy-in-a-patient-with-premature-ovarian-insufficiency-case-report
#2
Anna Calik-Ksepka, Monika Grymowicz, Weronika Bronkiewicz, Aleksandra Urban, Kamil Mierzejewski, Ewa Rudnicka, Roman Smolarczyk
Diagnosis of premature ovarian insufficiency is usually sudden and distressful for the patient in terms of facing infertility. However, some patients with POI have intermittent ovarian activity with an overall 5% probability of pregnancy. We report the case of 27-year-old woman with premature ovarian insufficiency treated with hormone replacement therapy, who six months after diagnosis conceived spontaneously. Apart from bleeding episodes in the first trimester, the pregnancy course was uneventful, and a healthy neonate was delivered...
September 2018: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/30357024/signs-and-symptoms-evaluation-and-management-of-genitourinary-tract-consequences-of-premature-ovarian-insufficiency
#3
REVIEW
Anna Calik-Ksepka, Monika Grymowicz, Ewa Rudnicka, Jolanta Skórska, Paulina Machura, Wojciech Pięta, Roman Smolarczyk
Premature ovarian insufficiency (POI) occurs in 1% of women under 40 years old. Hypoestrogenism associated with this condition may result in vaginal atrophy and urine incontinence, called genitourinary syndrome. The symptoms include: vaginal dryness, irritation, dyspareunia, and dysuria. There is relative lack of studies on the occurrence and treatment of genitourinary problems in women with POI. Prevalence rates vary from 17 to 54% depending on cause, duration of oestrogen depletion, and the treatment used...
September 2018: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/30357022/consequences-of-premature-ovarian-insufficiency-on-women-s-sexual-health
#4
REVIEW
Marzena Maciejewska-Jeske, Anna Szeliga, Błażej Męczekalski
Premature ovarian insufficiency (POI) is defined by amenorrhoea and decreased serum levels of oestrogens associated with increased serum gonadotropins concentrations before the age of 40 years. Patients suffering from POI present with irregular menses, either secondary or (less common) primary amenorrhoea, and subfertility. POI affects approximately 1 in 100 women by the age 40 years and 0.1% by 30 years of age. Both spontaneous and iatrogenic causes may induce POI, although up to 90% of POI cases are idiopathic...
September 2018: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/30357009/cardiovascular-health-in-patients-with-premature-ovarian-insufficiency-management-of-long-term-consequences
#5
REVIEW
Agnieszka Podfigurna, Błażej Męczekalski
Cardiovascular diseases (CVDs) represent the world's leading cause of death among women. Women with premature ovarian insufficiency (POI) may be at higher risk of cardiovascular disease, such as myocardial infarction or stroke, than women with normal menopause. The increased burden may be mediated by a worsening of cardiovascular risk factors, such as lipid profiles, with accompanying loss of ovarian function. In contrast, the increased burden may be caused by factors that precede and potentially contribute to both CVD events and ovarian decline, such as smoking...
September 2018: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/30357004/premature-ovarian-insufficiency-aetiopathology-epidemiology-and-diagnostic-evaluation
#6
REVIEW
Ewa Rudnicka, Jagoda Kruszewska, Klaudia Klicka, Joanna Kowalczyk, Monika Grymowicz, Jolanta Skórska, Wojciech Pięta, Roman Smolarczyk
Premature ovarian insufficiency (POI) is defined as a cessation of ovarian function before the age of 40 years. It is associated with hypoestrogenism and loss of residual follicles, both of which lead to menstrual abnormalities, pregnancy failures, and decreased health-related quality of life. The prevalence of POI is estimated at 1% in the general population. Current European Society of Human Reproduction and Embryology (ESHRE) diagnostic criteria include: amenorrhoea or oligomenorrhoea for at least four months and increased follicle-stimulating hormone (FSH) levels > 25 IU/l measured twice (with a four-week interval)...
September 2018: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/30356991/neurological-health-and-premature-ovarian-insufficiency-pathogenesis-and-clinical-management
#7
REVIEW
Radosław Słopień
Premature ovarian insufficiency (POI) is related to neurological problems through neurological symptoms of oestrogen deficiency, diseases caused by oestrogen deficiency, and neurological genetic diseases. Neurological symptoms of oestrogen deficiency are usually reported as climacteric symptoms. Diseases caused by oestrogen deficiency are dementia, cognitive decline, and Parkinsonism. Among genetic neurological disorders, ovarioleukodystrophy and fragile X-associated tremor/ataxia syndrome (FXTAS) are reported...
September 2018: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/30356982/mood-disorders-in-women-with-premature-ovarian-insufficiency
#8
REVIEW
Radosław Słopień
Premature ovarian insufficiency (POI) and related oestrogen deficiency is a cause of many psychological symptoms, including: depression, psychological tension, anxiety, mood lability, loss of libido, feelings of loss of femininity and attractiveness, and decreased self- and sexual esteem. Distress related to POI diagnosis may be even more confusing when POI is diagnosed in relation to serious health complications such as cancer, due to surgery or chemotherapy. Every case of POI requires coordinated medical advice with special attendance of a gynaecological endocrinologist, psychotherapist, and sometimes even a psychiatrist...
September 2018: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/30356979/bone-health-and-evaluation-of-bone-mineral-density-in-patients-with-premature-ovarian-insufficiency
#9
REVIEW
Anna Szeliga, Marzena Maciejewska-Jeske, Błażej Męczekalski
Oestrogens exert an influence on skeletal homeostasis during growth and adulthood. Regulation of osteoclasts and osteoblasts generation and apoptosis and prolongation of the lifespan of osteocytes are some of their actions on bone metabolism. Premature ovarian insufficiency (POI) and associated loss of oestrogen action on osteoclasts leads to trabecular perforation and loss of connectivity. Lack of oestrogens acting on osteoblast progenitors also causes a decrease in critical bone mass. Postmenopausal hypoestrogenism is associated with an increase in the number of lymphocyte B-cells expressing nuclear factor κB ligand (RANKL) in the bone marrow and elevated expression of RANKL by B-cells...
September 2018: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/30356967/reproduction-in-premature-ovarian-insufficiency-patients-from-latest-studies-to-therapeutic-approach
#10
REVIEW
Błażej Męczekalski, Marzena Maciejewska-Jeske, Agnieszka Podfigurna
Normal function of the ovaries, which is responsible for the hormonal and reproductive processes, is one of the most important determinants of fertility. Premature ovarian insufficiency (POI) is defined as cessation of menstrual cycle, increased serum follicle-stimulating hormone (FSH) levels, and decrease serum oestradiol levels in women before the age of 40 years. POI concerns about 1% of women and is characterised by severely diminished fertility. For the POI patient, this is one of the most dramatic problems...
September 2018: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/30150920/uterine-rupture-at-28-weeks-of-gestation-after-laparoscopic-myomectomy-a-case-report
#11
Katarzyna M Tomczyk, Maciej Wilczak, Paweł Rzymski
There are many reasons for sterility, and uterine malformations are of the greatest concern. Among uterine disorders, myomas play a significant role and are present in 27% of infertile women. The occurrence of myomas is frequent - 20-40% in women of reproductive age. Thus, for those infertile patients surgical treatment may be needed to preserve an opportunity to conceive. This case report refers to an uterine rupture at 28 weeks of gestation after laparoscopic myomectomy (3 months before conceiving). The myomectomy was conducted correctly and two layers of sutures on the myometrium were performed...
June 2018: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/30150919/bilateral-synchronous-ovarian-tumours-an-uncommon-case-and-review-of-the-literature
#12
Emre Günakan, Yusuf A Tohma, Asuman N Haberal, Ali Ayhan
Synchronous ovarian tumours are rare. Management of these patients can differ from that of patients with uniform tumours. We present a case of synchronous epithelial ovarian cancer and malignant mixed Müllerian tumour in different ovaries, its follow-up and management until death. To our knowledge this is the second case in the English literature to date. A 61-year-old woman with bilateral adnexal masses underwent complete debulking surgery for ovarian cancer. The final pathology was reported as malignant mixed Müllerian tumour in the right ovary with intact borders and stage 2 grade 3 serous carcinoma in the left ovary...
June 2018: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/30150918/-candida-lusitaniae-a-case-report-of-an-intraperitoneal-infection
#13
Sara Wawrysiuk, Tomasz Rechberger, Konrad Futyma, Paweł Miotła
Candida lusitaniae is a rare opportunistic yeast which is known for its resistance to amphotericin B (AmB). It is responsible for about 19.3% of all infections caused by non- Candida albicans species, and for about 1.7% of all cases of genitourinary candidiasis brought about by the entire spectrum of Candida species . Most commonly it occurs in patients with hematologic malignancies, especially when a patient is receiving chemotherapy. Candida lusitaniae infection usually presents with fungemia; however, only 7...
June 2018: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/30150917/presurgical-diagnostic-difficulties-in-an-asymptomatic-patient-with-primary-transitional-cell-carcinoma-of-the-oviduct-case-report
#14
Nabil Abdalla, Anna Wnuk, Seweryn Trojanowski, Alicja Jakimiuk, Pawel Stanirowski, Krzysztof Cendrowski, Wlodzimierz Sawicki
Primary transitional cell carcinoma of the fallopian tube is a very rare condition. We present a case of a 70-year-old asymptomatic Caucasian patient with an irregular solid right adnexal mass of 67 × 35 × 59 mm which was discovered during routine ultrasound pelvic examination. There was no acoustic shadow and the patient did not feel pain during examination. No evidence of metastases or ascites was found by ultrasound. There was moderate vascularization of the mass. The mass was considered malignant according to the subjective assessment of the examiner...
June 2018: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/30150916/clinical-implications-of-systemic-lupus-erythematosus-without-and-with-antiphospholipid-syndrome-in-peri-and-postmenopausal-age
#15
REVIEW
Bogna Grygiel-Górniak, Nattakarn Limphaibool, Mariusz Puszczewicz
Antiphospholipid syndrome (APS) in patients with systemic lupus erythematosus (SLE) displays a severe disease sub-phenotype with vascular manifestations ranging from peripheral thrombosis to neurologic and ophthalmic symptoms. The prevalence of morbidities including thrombosis, renal lesions, and cognitive impairment contributes to a higher risk of organ damage and a reduced quality of life in patients. In addition to the clinical heterogeneity, the diagnostic challenge is heightened in elderly patients as APS-related SLE is primarily diagnosed in young females...
June 2018: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/30150915/assessment-of-quality-of-life-in-women-using-femelis-meno
#16
Tomasz Paszkowski, Violetta Skrzypulec-Plinta
Over 30% of women suffering from menopausal symptoms use products of plant origin. This paper presents the results of a study devoted to evaluation of the efficacy of the Femelis Meno dietary supplement containing standardized flower pollen and pistil extracts (PI 82-GC FEM).
June 2018: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/30150914/effects-of-vitamin-b-12-folate-uric-acid-and-serum-biomarkers-of-inflammation-on-bone-mineral-density-in-postmenopausal-women
#17
Fatma Beyazit, Eren Pek
Introduction: Despite the accumulating evidence suggesting a possible relationship between femur and lumbar bone mineral density (BMD) and serum uric acid (UA), it is unclear whether alterations in UA levels reflect any underlying subclinical inflammatory conditions in postmenopausal osteoporosis. In addition, the mechanistic link between osteoporosis and dietary factors including vitamin B12 and folate in postmenopausal women is still obscure. The aim of the present study is to investigate the association between serum vitamin B12 , folate, UA, and subclinical inflammatory markers and BMD measurements in postmenopausal women...
June 2018: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/30150913/malignant-transformation-in-mature-cystic-teratoma-of-the-ovary-a-retrospective-study-of-eight-cases-and-review-of-literature
#18
Ruchi Rathore, Sonal Sharma, Sarla Agarwal
Introduction: Mature cystic teratoma (MCT) is the most common type of ovarian germ cell neoplasm, but occasionally it may undergo malignant change in any one of its elements. In this study, these rarely encountered tumors, occurring over a period of 25 years, were studied. Material and methods: A retrospective, tertiary hospital-based study was carried out in all histopathologically diagnosed cases of MCT (230) of the ovary from January 1990 to December 2014. The clinicopathological features of malignant transformation (MT) in MCT of the ovary were retrieved from the archives of the Department of Pathology and were analyzed...
June 2018: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/30150912/determining-the-factors-influencing-the-intimate-relationship-between-sexual-satisfaction-and-dyadic-adjustment-in-postmenopausal-women
#19
Fatma Beyazit, Başak Sahin
Introduction: Identifying and characterizing sexual dysfunction is crucial in order to improve the quality of the marital relationship in postmenopausal women. Regarding this, the present study aimed to determine the association of menopausal characteristics with sexual satisfaction and marital adjustment. Material and methods: This cross-sectional study was conducted on 89 postmenopausal women chosen using an improbable randomized sampling method. A questionnaire that collects demographic characteristics, the Dyadic Adjustment Scale (DAS) and The Golombok Rust Inventory of Sexual Satisfaction (GRISS) index were used to collect relevant data during the survey...
June 2018: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/30150911/perimenopause-vasomotor-symptoms-coronary-atherosclerosis-and-risk-of-myocardial-infarction-during-menopause-the-cardiologist-s-perspective
#20
Stefano Savonitto, Luca A Ferri, Delia Colombo
Myocardial infarction (MI) is rare in pre-menopausal women, and in most cases has a gender-specific pathogenesis. After menopause, MI incidence increases gradually to equalize men's rate in the eighth decade of age, with similar pathogenesis. This epidemiological observation has raised a number of hypotheses on the protective effect of estrogen against atherosclerosis and its related diseases. However, MI has a multifactorial pathogenesis with variable contributions of inflammation, eroded or ruptured atherosclerotic plaques, vasoconstriction and thrombosis...
June 2018: Przeglad Menopauzalny, Menopause Review
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