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Gastroenterology Research

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https://www.readbyqxmd.com/read/29511414/histologic-characterization-of-kratom-use-associated-liver-injury
#1
Michael Riverso, Michael Chang, Consuelo Soldevila-Pico, Jinping Lai, Xiuli Liu
Kratom is an herbal product derived from the leaves of Southeast Asian Mitragyna speciosa trees. It has traditionally been used by indigenous people to relieve fatigue and manage pain, diarrhea, or opioid withdrawal. The use of kratom has become more commonplace in the United States for similar purposes. Only rare reports of kratom liver toxicity exist in the literature but without histologic characterization. Herein, we report one case of kratom use-associated liver toxicity in a 38-year-old patient. The patient complained of dark colored urine and light colored stools after using kratom...
February 2018: Gastroenterology Research
https://www.readbyqxmd.com/read/29511413/a-rare-cause-of-abdominal-pain-and-mass-in-an-18-year-old-patient-a-diagnostic-dilemma
#2
Hassan Tariq, Muhammad Umar Kamal, Vamshidhar Vootla, Mohamed ElZaeedi, Masooma Niazi, Brian Gilchrist, Ariyo Ihimoyan, Anil Dev, Sridhar Chilimuri
We present a case of an 18-year-old male who presented with complains of abdominal pain, nausea and vomiting for 2 years. An esophagogastroduodenoscopy (EGD) revealed a 3 mm nodule on the lesser curvature of the stomach and prominent gastric folds. Biopsy of the nodule revealed a well-differentiated neuroendocrine tumor (NET) in lamina prop with focal extension into muscularis mucosa consistent with a gastric carcinoid. Tumor cells stained with neuron-specific enolase (NSE), chromogranin and synaptophysin only...
February 2018: Gastroenterology Research
https://www.readbyqxmd.com/read/29511412/gastric-outlet-and-duodenal-obstruction-as-a-complication-of-migrated-gastrostomy-tube-report-of-two-cases-and-literature-review
#3
Jamil Shah, Tagore Sunkara, Krishna Sowjanya Yarlagadda, Prashanth Rawla, Vinaya Gaduputi
Percutaneous endoscopic gastrostomy (PEG) is a well-recognized procedure for providing enteral feeding and long-term enteral nutritional support. Although it is mostly well tolerated, complications, sometimes mechanical in nature, do occur. Rare, and often initially unrecognized, late complications of PEG tube placement are gastric outlet obstruction and duodenal obstruction. Simple adjustment of the gastrostomy tube will lead to the improvement of the patient's clinical condition and prevent further complications...
February 2018: Gastroenterology Research
https://www.readbyqxmd.com/read/29511411/gastric-diverticula-a-review-and-report-of-two-cases
#4
Daryl Ramai, Andrew Ofosu, Madhavi Reddy
Gastric diverticula represent the rarest of gastrointestinal diverticula. While similar to duodenal, jejunal and colonic diverticula, gastric diverticula are found incidentally upon upper endoscopy and are mostly asymptomatic. However, larger diverticula can lead to symptoms such as upper abdominal pain, nausea, emesis, and dyspepsia. Some patients may present with dramatic presentations including ulceration, hemorrhage, or perforation. Clinicians should be aware that diagnostic imaging may not always detect the presence of gastric diverticula...
February 2018: Gastroenterology Research
https://www.readbyqxmd.com/read/29511410/a-case-of-adolescent-cronkhite-canada-syndrome
#5
Mikaell Alexandre Gouvea Faria, Bruna Basaglia, Vinicius Quintiliano Moutinho Nogueira, Tatiana Barros Gama Ferraz de Mendonca, Roberto Luiz Kaiser Junior, Idiberto Jose Zotarelli Filho, Luiz Gustavo de Quadros
The Cronkhite-Canada syndrome (CCS) was first reported in 1955, since then more than 500 cases have been reported, indicating an estimated incidence of one case per 1 million inhabitants. The syndrome occurs predominantly in male, with a ratio of three males to two females. Because of the rarity of the syndrome, there are no evidence-based therapies and the treatments described include a combination of therapies, but none is consistently effective. Surgery is usually reserved for the treatment of complications...
February 2018: Gastroenterology Research
https://www.readbyqxmd.com/read/29511409/fatal-acute-liver-failure-with-intravenous-amiodarone-a-case-report-and-literature-review
#6
Vijay Gayam, Mazin Khalid, Sumit Dahal, Pavani Garlapati, Arshpal Gill, Ragin Alex, Mohammad Mansour
Amiodarone is a drug which frequently causes elevated transaminases. However, acute liver failure has been rarely reported. Here, we present a case of fatal acute liver failure following the administration of intravenous amiodarone. It is important to be aware of this rare but potentially fatal complication of intravenous amiodarone so that it can be withdrawn immediately at the first sign of hepatic impairment.
February 2018: Gastroenterology Research
https://www.readbyqxmd.com/read/29511408/worsening-of-acute-cholangitis-caused-by-a-bile-duct-stone-after-hospitalization-a-case-series
#7
Tetsuro Akashi, Yuichi Tachibana, Susumu Matsuo, Junya Gibo
Acute cholangitis is a fatal condition if inadequately treated. It is possible to underestimate the severity of the condition because bacterial cultures are not immediately available. We evaluated the clinical features of patients with cholangitis due to bile duct stones who were diagnosed with severe bacteremia at the time of hospitalization, but not at the time of the initial visit. We conducted a retrospective analysis of cases of endoscopic retrograde cholangiopancreatography performed between January 2007 and October 2011 in patients with bile duct stones complicated by cholangitis...
February 2018: Gastroenterology Research
https://www.readbyqxmd.com/read/29511407/autologous-graft-versus-host-disease-of-the-gastrointestinal-tract-in-patients-with-multiple-myeloma-and-hematopoietic-stem-cell-transplantation
#8
Muhammad B Hammami, Rebecca Talkin, Ahmad M Al-Taee, Martin W Schoen, Sagun D Goyal, Jin-Ping Lai
Multiple myeloma (MM) is the most common indication for autologous hematopoietic stem cell transplantation (HSCT) in North America. Despite occurring in up to 50% of patients undergoing allogeneic HSCT, the incidence of graft-versus-host disease (GVHD) after autologous HSCT is reportedly only 5-20%. Gastrointestinal involvement with graft-versus-host disease (GI GVHD) is a common and serious complication of allogeneic HSCT. GI GVHD after autologous transplant, which is referred to as autologous GVHD (auto-GVHD), has also been described...
February 2018: Gastroenterology Research
https://www.readbyqxmd.com/read/29511406/analysis-of-helicobacter-pylori-genotypes-amongst-jordanians-dental-plaque-samples
#9
Mohammad Abu-Lubad, Hamed Alzoubi, Dua'a Jarajreh, Alaa Al Sawalqa, Holger Bruggemann, Eman Albataineh, Amin Aqel, Munir Al-Zeer
Background: Helicobacter pylori ( H. pylori ) infection has been associated with gastritis, gastric ulcer, mucosa-associated lymphoid tissue lymphoma and gastric cancer. The prevalence of H. pylori virulence genes have been studied in different populations and from different sources of samples but their prevalence has not been studied in dental plaque in Jordanian people; therefore, the aim of this study was to determine the genotypes of H. pylori isolated from dental plaque samples. Methods: Dental plaque samples were collected from 60 Jordanian volunteers...
February 2018: Gastroenterology Research
https://www.readbyqxmd.com/read/29511405/comparative-effectiveness-of-vedolizumab-vs-infliximab-induction-therapy-in-ulcerative-colitis-experience-of-a-real-world-cohort-at-a-tertiary-inflammatory-bowel-disease-center
#10
Chaitanya Allamneni, Krishna Venkata, Huifeng Yun, Fenglong Xie, Lindsey DeLoach, Talha A Malik
Background: Vedolizumab (VDZ), an adhesion molecule inhibitor and infliximab (IFX), a tumor necrosis factor (TNF) blocker, are both approved as first-line induction agents in moderately to severely active ulcerative colitis (UC). However, there are no head-to-head studies comparing the relative effectiveness of the two agents. Here we provide a real-world comparison of these two agents. Methods: We conducted an ambidirectional cohort study of adult UC patients seen at our tertiary inflammatory bowel disease (IBD) center from 2012 to 2017...
February 2018: Gastroenterology Research
https://www.readbyqxmd.com/read/29511404/outcomes-of-a-physician-controlled-wire-guided-cannulation-of-the-bile-duct-using-a-novel-sphincterotome-a-single-center-prospective-study
#11
Koichiro Mandai, Koji Uno, Yuki Ueda, Yusuke Okada, Kenjiro Yasuda
Background: Efficacy of a physician-controlled wire-guided cannulation of the bile duct has been reported. This study aimed to evaluate a novel sphincterotome with a short tip and a short wire, which can be bowed compactly compared to conventional sphincterotomes. Methods: This was a single-arm, single-center, prospective study. We enrolled patients with choledocholithiasis and/or obstructive jaundice and/or cholangitis for whom endoscopic sphincterotomy was planned...
February 2018: Gastroenterology Research
https://www.readbyqxmd.com/read/29511403/assessment-of-knowledge-attitudes-and-practices-regarding-chronic-hepatitis-c-treatment-and-its-challenges-a-survey-of-internal-medicine-residents-in-a-community-hospital
#12
Mazin Khalid, Sumit Dahal, Vijay Gayam, Amrendra Mandal, Muhammad R Hossain, Osama Mukhtar, Mowyad Khalid, Pavani Garlapati, Mohammed Mansour
Background: Despite recent advances in chronic hepatitis C (CHC) treatment, only a small proportion of patients are connected with care and receive treatment. Internal medicine (IM) residents spend nearly one-third of their training in primary care settings and play a crucial role in diagnosing and counseling patients as well as linking patients with care and following up. Methods: IM residents in a community hospital completed an anonymous questionnaire regarding their knowledge, attitude, and practice associated with CHC treatment and its challenges...
February 2018: Gastroenterology Research
https://www.readbyqxmd.com/read/29511402/metastatic-renal-cell-carcinoma-as-solitary-subcentimeter-polypoid-gastric-mucosal-lesions-clinicopathologic-analysis-of-five-cases
#13
Amanda Hemmerich, Mohanad Shaar, Rebecca Burbridge, Cynthia D Guy, Shannon J McCall, Diana M Cardona, Xuchen Zhang, Jinping Lai, Xuefeng Zhang
Background: The stomach is an uncommon site for metastatic carcinoma. Approximately 6% of renal cell carcinomas (RCCs) may metastasize to the stomach. The majority of the reported metastatic RCCs in the stomach presented as large masses or ulcers greater than a centimeter in size. It is very rare to encounter metastatic RCC as a solitary small polypoid gastric mucosal lesion. Methods: In this study, we collected surgical pathology cases of gastric metastasis from RCC that measured 1...
February 2018: Gastroenterology Research
https://www.readbyqxmd.com/read/29511401/aquanet-bowel-cleansing-device-versus-oral-sodium-picosulfate-for-pre-endoscopy-bowel-preparation-propensity-score-analysis-for-interventional-effectiveness-evaluation
#14
Roberto L Kaiser Junior, Luiz G de Quadros, Mikaell A G Faria, Fernanda S L Kaiser, Juan C O Campo, Idiberto J Zotarelli Filho
Background: Colonoscopy procedures are commonly performed and have high success rates. However, poor or inadequate bowel preparation is one of the most common reasons for a repeated or failed colonoscopy. We therefore performed an observational study followed by propensity score modeling to evaluate and compare the quality of bowel preparation with the use of Aquanet bowel cleansing devices (BCDs) versus the use of oral sodium picosulfate solution. Methods: We performed a prospective cross-sectional study to compare the quality of pre-endoscopic bowel preparation using a BCD with oral solution...
February 2018: Gastroenterology Research
https://www.readbyqxmd.com/read/29511400/internists-perceptions-of-proton-pump-inhibitor-adverse-effects-and-impact-on-prescribing-practices-results-of-a-nationwide-survey
#15
Jacob E Kurlander, Mark Kolbe, Joel H Rubenstein, Caroline R Richardson, Michele Heisler, Arlene Weissman, Raymond De Vries, Sameer D Saini
Background: Observational studies have linked proton pump inhibitors (PPIs) with serious adverse effects. The study aimed to evaluate internists' perceptions of PPI harms and effects on prescribing. Methods: This was an online survey of a representative sample of the American College of Physicians in 2013. We queried familiarity with and concern about PPI adverse effects (1 - 7 Likert-type scales, anchored by "not at all" and "extremely"). We also asked how frequently (often, sometimes, rarely, or never) participants used any of three "de-escalation" strategies to stop or reduce PPIs because of concern about adverse effects: reducing patients' PPI dose, switching to H2 blocker, or discontinuing PPI...
February 2018: Gastroenterology Research
https://www.readbyqxmd.com/read/29511399/clinical-implication-of-enlarged-prostate-in-patients-with-the-ileal-pouch-anal-anastomosis-for-inflammatory-bowel-disease
#16
Lei Lian, Emmanuel Obusez, Erick M Remer, Manoj Monga, Bo Shen
Background: Enlarged prostate is often noticed in patients with ileal pouch-anal anastomosis (IPAA) in our clinical practice. The aims were to identify the factors associated with enlarged prostate and to investigate its clinical implications. Methods: IPAA patients with available prostate imaging after IPAA were included. Prostate length and width were measured in the axial plane and height in coronal plane. Prostate volume was calculated with the formula (length × width × height) × π/6...
February 2018: Gastroenterology Research
https://www.readbyqxmd.com/read/29511398/a-review-of-double-common-bile-duct-and-its-sequelae
#17
REVIEW
Sindhura Kolli, Denzil Etienne, Madhavi Reddy, Ghulamullah Shahzad
A double or accessory common bile duct (ACBD) is a rare congenital anomaly. We report the case of a 60-year-old American Asian male, who was found to have a double or duplicated common bile duct after being admitted for evaluation of a pancreatic mass. A duplicated bile duct has the same mucosa histologically as a single bile duct. However, the opening of a duplicated bile duct lacks a sphincter allowing retrograde flow of gut contents which results in a higher probability of intraductal calculus formation...
February 2018: Gastroenterology Research
https://www.readbyqxmd.com/read/29317950/a-biliobronchial-fistula-in-a-patient-with-hepatocellcular-carcinoma-treated-with-chemoembolization-diagnosed-by-hepatobiliary-iminodiacetic-acid-scan-and-managed-by-endoscopic-retrograde-cholangiopancreatography
#18
Yousef Nassar, Sven Hida, Seth Richter
A biliobronchial fistula is an abnormal communication between the biliary tract and the bronchial tree. It may be a rare complication after treatment of hepatocellular carcinoma with transcatheter arterial chemoembolization (TACE). We present a case of a 71-year-old man that developed a biliobronchial fistula as a complication of hepatocellular carcinoma treated with TACE. It was successfully diagnosed by hepatobiliary iminodiacetic acid (HIDA) scan and treated with endoscopic retrograde pancreatography.
December 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/29317949/superior-mesenteric-vein-thrombosis-in-a-patient-on-oral-contraceptive-pills
#19
Prashanth Rawla, Jeffrey Pradeep Raj, Krishna Chaitanya Thandra, Sathayajit S Bandaru
Abdominal pain is a common occurrence, and it may vary from subtle pain to very severe pain due to a variety of causes, some of which may even be life-threatening. It is commonly believed that a life-threatening cause is almost always very severe with regards to the symptomatology. However, here in this case report, we report an unusual case of abdominal pain due to superior mesenteric vein (SMV) thrombosis in an otherwise healthy lady who was on an oral contraceptive agent for the last 2 years. She presented with mild abdominal pain for 3 days, and a computed tomography scan of the abdomen which was done to rule out common surgical causes of abdominal pain revealed a thrombus in the SMV...
December 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/29317948/colon-carcinoma-presenting-as-streptococcus-anginosus-bacteremia-and-liver-abscess
#20
Prashanth Rawla, Anantha R Vellipuram, Sathyajit S Bandaru, Jeffrey Pradeep Raj
A collection of dead white blood cells within the liver is called a liver abscess, and pyogenic liver abscess (PLA) is the most common type. PLA is commonly associated with biliary tract infections. However, in this case report, we present a rare cause of Streptococcus anginosus bacteremia and PLA which is associated with a carcinoma of the colon at the splenic flexure. The presentation mimicked a cholecystitis clinically, but the radio-imaging revealed a liver abscess. Blood cultures revealed an uncommon etiological agent, S...
December 2017: Gastroenterology Research
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