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Gastroenterology Research

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https://www.readbyqxmd.com/read/28058081/fungal-esophagitis-presenting-with-esophagitis-dissecans-superficialis-cause-or-concurrence-a-diagnostic-conundrum
#1
Rashmee Patil, Tagore Sunkara, Mel A Ona, Vinaya Gaduputi, Madhavi Reddy
Esophagitis dissecans superficialis (EDS) is a rare desquamative disorder of the esophagus. It is characterized by sheets of sloughed squamous tissue with normal underlying mucosa. We present a case of a 68-year-old man with severe anemia and a positive fecal occult blood test who was found to have features suggestive of EDS during endoscopy. However, histological features were suggestive of both EDS and fungal esophagitis. To our knowledge, this is the first reported case in literature which discusses the clinical scenario of fungal infection being a possible etiology rather than a commonly accepted differential diagnosis of EDS...
December 2016: Gastroenterology Research
https://www.readbyqxmd.com/read/28058080/cecal-leiomyoma-can-we-attempt-endoscopic-resection
#2
Kanthi Rekha Badipatla, Chandana Kamireddy, Masooma Niazi, Suresh Kumar Nayudu
Gastrointestinal leiomyomas are smooth muscle tumors arising from the muscularis mucosae, muscularis propriae and possibly from smooth muscle of the vessel wall. Management depends on the size, location and the clinical scenario. Endoscopic snare cauterization with or without saline lift has been described in literature for tumors involving the left colon. To the best of our knowledge, endoscopic resection of right colon leiomyoma was never attempted in the past. We present a case of cecal leiomyoma which was resected endoscopically...
December 2016: Gastroenterology Research
https://www.readbyqxmd.com/read/28058079/zollinger-ellison-syndrome-a-rare-case-of-chronic-diarrhea
#3
Ali Aamar, Kamraan Madhani, Hafeezulhassan Virk, Zeeshan Butt
Zollinger-Ellison syndrome (ZES) is caused by hypersecretion of gastrin from duodenal or pancreatic gastrinomas. We report a case of a 57-year-old female who presented with chronic diarrhea. CT abdomen showed multiple liver masses. Liver biopsy suggested metastatic well-differentiated neuroendocrine tumor. Serum gastrin level was markedly elevated. MRI abdomen, somatostatin receptor scintigraphy and endoscopic ultrasound failed to reveal primary site of the tumor. Upper gastrointestinal endoscopy showed hyperplastic gastric folds and multiple duodenal ulcers consistent with ZES...
December 2016: Gastroenterology Research
https://www.readbyqxmd.com/read/28058078/extramammary-paget-s-disease-of-anal-canal-associated-with-rectal-adenoma-without-invasive-carcinoma
#4
Vaibhav Chumbalkar, Timothy A Jennings, Sanaz Ainechi, Edward C Lee, Hwajeong Lee
Extramammary Paget's disease (EMPD) is a rare disease which is found in apocrine-rich locations such as anogenital region, axilla and rarely in other sites. Perianal EMPD is often reported as the involvement of perianal skin, but involvement of anal mucosa is very rare. Based on pathogenesis and association with either synchronous or metachronous malignancy, EMPD can be divided into primary and secondary types. Treatment approach for these two types of Paget's disease and their prognosis is different, thus it is important to make the distinction...
December 2016: Gastroenterology Research
https://www.readbyqxmd.com/read/28058077/immunostaining-detection-of-cytomegalovirus-in-gastrointestinal-biopsies-clinicopathological-correlation-at-a-large-academic-health-system
#5
Xiaoyan Liao, Sharon L Reed, Grace Y Lin
BACKGROUND: Cytomegalovirus (CMV) infection can be asymptomatic in healthy individuals but may cause serious complications in immunocompromised patients. We investigated the clinicopathological correlation of CMV in gastrointestinal (GI) biopsies at our institute between January 1, 2013 and December 31, 2015. METHODS: A total of 105 non-neoplastic GI biopsies tested positive for CMV by immunohistochemistry (IHC). The IHC results were stratified as "true positive" if > 2 cells stained, or "rare positive" if only 1 - 2 cells stained...
December 2016: Gastroenterology Research
https://www.readbyqxmd.com/read/28058076/non-alcoholic-fatty-pancreatic-disease-a-review-of-literature
#6
REVIEW
Hassan Tariq, Suresh Nayudu, Sai Akella, Mariela Glandt, Sridhar Chilimuri
There is an epidemic of obesity worldwide. The prevalence of obesity has doubled over the last three decades. Obesity, especially abdominal obesity is associated with insulin resistance that can lead to pancreatic steatosis and non-alcoholic fatty pancreatic disease (NAFPD). NAFPD describes a phenotype entity ranging from deposition of fat in the pancreas to pancreatic inflammation, and resultant fibrosis, which is similar to that of non-alcoholic fatty liver disease (NAFLD). NAFPD may represent a meaningful manifestation of metabolic syndrome...
December 2016: Gastroenterology Research
https://www.readbyqxmd.com/read/27785332/epstein-barr-virus-positive-diffuse-large-b-cell-lymphoma-involving-the-colon-in-a-patient-with-ulcerative-pancolitis-and-polymyositis-on-long-term-methotrexate-therapy
#7
Michael D Chang, Merry-Jennifer Markham, Xiuli Liu
The link between immunosuppressive therapy and increased lymphoma risk is well established in patients with solid organ transplantation. Epstein-Barr virus-positive (EBV) diffuse large B-cell lymphoma (DLBCL) is known to be a complication in patients receiving methotrexate for rheumatoid arthritis, and the risk of lymphoma in inflammatory bowel disease (IBD) has raised concerns regarding the lymphoproliferative potential of immunomodulatory therapy. In this report, we describe a case of EBV-positive DLBCL arising within the colon of a patient affected by ulcerative pancolitis...
October 2016: Gastroenterology Research
https://www.readbyqxmd.com/read/27785331/congenital-esophageal-duplication-cyst-a-rare-cause-of-dysphagia-in-an-adult
#8
Nikhil Sonthalia, Samit S Jain, Ravindra G Surude, Ashok R Mohite, Pravin M Rathi
Esophageal duplication cyst is a rare congenital embryonal gastrointestinal (GI) malformation which is diagnosed most commonly in childhood. In adults, they can present with a variety of symptoms ranging from dysphagia, chest pain, epigastric discomfort, and vomiting to more serious complications including infections, hemorrhage, and ulcerations. A 30-year-old male presented with gradually progressive dysphagia to solids for 4 months without significant weight loss. Clinical examination and routine laboratory examination were unrevealing...
October 2016: Gastroenterology Research
https://www.readbyqxmd.com/read/27785330/epstein-barr-virus-associated-acute-liver-failure-present-in-a-67-year-old-immunocompetent-female
#9
Wei Zhang, Betty Chen, Yongxin Chen, Robin Chamberland, Alexa Fider-Whyte, Julia Craig, Chintalapati Varma, Alex S Befeler, Adrian M Di Bisceglie, Peter Horton, Jin-Ping Lai
Acute liver failure (ALF) is a rare illness with a high mortality rate. The only favorable management is emergent liver transplantation. About 13% of ALF cases have no clear etiology. Epstein-Barr virus (EBV)-associated ALF accounts for less than 1% of all ALF cases, and is seen mostly in adults younger than 40 years. There are only a few cases of EBV-associated ALF in elderly immunocompromised adults. We report a case of ALF in an immunocompetent 67-year-old woman caused by EBV infection that was treated by orthotopic liver transplantation (OLT)...
October 2016: Gastroenterology Research
https://www.readbyqxmd.com/read/27785329/no-need-of-fascia-closure-to-reduce-trocar-site-hernia-rate-in-laparoscopic-surgery-a-prospective-study-of-200-non-obese-patients
#10
Rikki Singal, Muzzafar Zaman, Amit Mittal, Samita Singal, Karamjot Sandhu, Anshu Mittal
BACKGROUND: Laparoscopy is widely practiced and offers realistic benefits over conventional surgery. Port closure is important after a laparoscopic procedure to prevent port site incisional hernia. Larger port size and increasing numbers of ports needed to perform more complex laparoscopic procedures are likely to increase the incidence of port site hernias (PSHs). PSHs tend to develop more frequently at umbilical and midline port sites due to the thinness of the umbilical skin and weaknesses in the linea alba...
October 2016: Gastroenterology Research
https://www.readbyqxmd.com/read/27785328/measures-of-autonomic-dysfunction-in-diabetic-and-idiopathic-gastroparesis
#11
Mohammad Khalid Mohammad, Dominique J Pepper, Archana Kedar, Feriyl Bhaijee, Babajide Familoni, Hani Rashed, Teresa Cutts, Thomas L Abell
BACKGROUND: Gastroparesis is a condition classically characterized by delayed gastric emptying and is associated with considerable morbidity. While the etiology of gastroparesis remains elusive, autonomic dysfunction may play an important role, especially as many patients with gastroparesis also have diabetes. The aim of this study was to determine whether measures of autonomic function differ between adults with diabetic gastroparesis (DG) and adults with idiopathic gastroparesis (IG)...
October 2016: Gastroenterology Research
https://www.readbyqxmd.com/read/27785327/spontaneous-perforation-of-gallbladder-case-report
#12
Satish Kumar Sheoran, Rajiv Nandan Sahai, Jagmohan Indora, Upender Chand Biswal
The main cause of perforation of the gallbladder is cholecystitis with or without cholelithiasis. In old age, spontaneous perforation of gallbladder can be due to decrease in its blood supply, which can be due to atherosclerosis, focal vasospasm or localized vasculitis. Perforation of gallbladder is associated with high morbidity and mortality, if left untreated. Here we report a case of a 60-year-old male with perforation of gallbladder.
June 2016: Gastroenterology Research
https://www.readbyqxmd.com/read/27785326/a-rare-disease-of-the-digestive-tract-esophageal-melanosis
#13
Sebahattin Destek, Vahit Onur Gul, Serkan Ahioglu, Yesim Erbil
Esophageal melanosis which is characterized by melanocytic proliferation in the squamous epithelium of the esophagus and melanin accumulatin of esophageal mucosa (EM) is a rare disease of the digestive system. Although esophageal melanosis is considered to be a benign disease, its etiology is not cleared and has been reported to be the precursor lesion of esophageal primary melanomas. In this report, we aimed to note esophageal melanosis in a 55-year-old female case who applied to our clinic with difficulty in swallowing, burning behind the breastbone in the stomach, heartburn, indigestion, and pain in the upper abdomen after endoscopic and pathologic evaluation...
June 2016: Gastroenterology Research
https://www.readbyqxmd.com/read/27785325/the-role-of-percutaneous-endoscopic-transgastric-jejunostomy-in-the-management-of-enteral-tube-feeding
#14
Ezekiel Wong Toh Yoon
Feeding-related adverse events after percutaneous endoscopic gastrostomy (PEG) such as aspiration pneumonia can impede the use of PEG. Percutaneous endoscopic transgastric jejunostomy (PEG-J) using large-bore jejunal tubes with gastric decompression function may improve outcomes by circumventing gastric passage during enteral nutrition and improving drainage of excessive gastric secretions. This report describes a case where PEG-J was successful in maintaining enteral tube feeding in a 72-year-old man when PEG feeding was not tolerated...
June 2016: Gastroenterology Research
https://www.readbyqxmd.com/read/27785324/role-of-rectal-diclofenac-suppository-for-prevention-and-its-impact-on-severity-of-post-endoscopic-retrograde-cholangiopancreatography-pancreatitis-in-high-risk-patients
#15
Sandeep Patil, Vikas Pandey, Nilesh Pandav, Meghraj Ingle, Aniruddha Phadke, Prabha Sawant
BACKGROUND: The aim was to study the role of rectal diclofenac in prevention of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis and its impact on severity of post-ERCP pancreatitis. METHODS: We conducted a single-center, prospective, open-labeled, randomized trial for evaluating the use of rectal diclofenac in prevention of post-ERCP pancreatitis in high-risk patients. We assessed 526 patients coming for ERCP for different indications. Four hundred patients were eligible for the study...
June 2016: Gastroenterology Research
https://www.readbyqxmd.com/read/27785323/increased-expression-of-pyloric-er%C3%AE-is-associated-with-diabetic-gastroparesis-in-streptozotocin-induced-male-diabetic-rats
#16
Stephen Crimmins, Rebecca Smiley, Kerry Preston, Amy Yau, Richard Mccallum, Mohammed Showkat Ali
BACKGROUND: Gastroparesis is a significant co-morbidity affecting up to 50% of patients with diabetes and is disproportionately found in women. Prior studies have suggested that loss of interstitial cells of Cajal, hyperglycemia, and nitric oxide dysfunction are potential causes of gastroparesis. Since diabetic gastroparesis affects more women than men, we performed an exploratory study with a diabetic rat model to determine if sex hormone signaling is altered in those where gastroparesis develops...
June 2016: Gastroenterology Research
https://www.readbyqxmd.com/read/27785322/common-inflammatory-disorders-and-neoplasia-of-the-ileal-pouch-a-review-of-histopathology
#17
REVIEW
David Hernandez Gonzalo, Amy L Collinsworth, Xiuli Liu
Ileal pouch-anal anastomosis (IPAA) is the standard restorative procedure after proctocolectomy in patients with ulcerative colitis (UC) who require colectomy. The ileal pouch is susceptible to a variety of insults including mechanical injury, ischemia, fecal stasis, and infectious agents. In addition, the development of recurrent and idiopathic inflammatory bowel disease and neoplasia may occur in the ileal pouch. Although clinical, endoscopic, and radiographic examination can diagnose many ileal pouch diseases, histologic examination plays an essential role in diagnosis and management, particularly in cases with antibiotic refractory chronic pouchitis and pouch neoplasia...
June 2016: Gastroenterology Research
https://www.readbyqxmd.com/read/27785321/the-genoa-method-in-alcohol-dependence-treatment
#18
Gianni Testino, Alessandro Sumberaz, Paolo Borro
No abstract text is available yet for this article.
February 2016: Gastroenterology Research
https://www.readbyqxmd.com/read/27785320/mixed-adenocarcinoid-tumor-presenting-as-acute-appendicitis
#19
Kalyani Regeti, Waqas Jehangir, Shoaib Zafar, Shuvendu Sen, Ibrahim Sidhom, Abdalla Yousif
Mixed adenocarcinoid tumors are not uncommon neoplasms of appendix. The clinical presentation of these tumors is often similar to that of acute appendicitis or may present as asymptomatic. These tumors are found incidentally during histopathological examination of the resected appendix following appendectomy or other abdominal procedures. Mixed adenocarcinoids usually behave as adenocarcinomas with rapid metastasis, so prognosis depends upon how aggressive the tumor behaves. The present study reports a case of a 53-year-old male who presented with abdominal pain and fever for 1 day and underwent successful appendectomy and recovered later...
February 2016: Gastroenterology Research
https://www.readbyqxmd.com/read/27785319/new-biochemical-parameters-in-the-differential-diagnosis-of-ascitic-fluids
#20
Anabela Angeleri, Adriana Rocher, Beatriz Caracciolo, Marcela Pandolfo, Luis Palaoro, Beatriz Perazzi
BACKGROUND: In the cases of ascitis, it is essential to determine their origin using the parameters obtained by the cytological and biochemical examinations. The aim of this study was to evaluate the usefulness of different biochemical markers and the number of cells in the differential diagnosis of ascitic fluid (AF). METHODS: One hundred ninety-one cases of AF were studied, who were admitted to the hospital from January 01, 2009 to December 31, 2014. One hundred fifty-two of them were included in the analysis, and the remaining 39 were excluded because they had more than one associated pathology, clotted or hemolyzed...
February 2016: Gastroenterology Research
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