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Gastroenterology Research

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https://www.readbyqxmd.com/read/28496542/multiple-duodenal-lipomas-as-a-rare-cause-of-upper-gastrointestinal-obstruction-case-report-and-literature-review
#1
Maowei Pei, Mingrong Hu, Wenbin Chen, Chao Qin
Duodenal lipomas are rare benign tumors and pose a diagnostic challenge as their symptoms are non-specific. In this article, we reported a case of duodenal lipoma presenting as upper gastrointestinal obstruction and reviewed the literature on relevant clinical manifestation, diagnosis and treatment. Our review of literature indicated that multiple duodenal lipomas as a cause of upper gastrointestinal obstruction as reported here are extremely rare. The preoperative computed tomography and magnetic resonance imaging are the key to diagnosis, and surgical resection is the most effective means for the management of such duodenal lipomas...
April 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28496541/atypical-presentation-of-gastric-volvulus
#2
Denzil Etienne, Mel A Ona, Madhavi Reddy
Gastric volvulus has been reported in all age groups; however, it is typically diagnosed in the elderly. Organo-axial volvulus is the most common type, followed by the mesentero-axial and the combined types. Depending on the etiology, gastric volvulus can also be classified as primary (idiopathic) or secondary. Treatment of acute gastric volvulus involves laparoscopic or endoscopic procedures/maneuvers, depending on the severity of symptoms and surgical eligibility of the patient. Chronic gastric volvulus is typically managed conservatively, although laparoscopic or endoscopic interventions can also be employed depending on the severity of presentation...
April 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28496540/recombinant-factor-viia-use-for-endoscopic-retrograde-cholangiopancreatography-with-sphincterotomy-in-a-patient-with-choledocholithiasis-and-unusual-coagulopathy
#3
Molham Abdulsamad, Pavithra Reddy, Suvarna Guvvala, Anil Dev
Endoscopic retrograde cholangiopancreatography (ERCP) is a procedure that combines the use of endoscopy and fluoroscopy to diagnose and treat pancreaticobiliary disorders. The risks of ERCP include pancreatitis, infection, bleeding and perforation. Bleeding during ERCP typically develops after sphincterotomy, hence patients should be screened and tested for coagulopathy before undergoing ERCP. Coagulopathy is a major risk factor for ERCP-related bleeding. Inherited factor VII (FVII) deficiency is a rare autosomal recessive hemorrhagic disorder that can lead to significant coagulopathy and severe bleeding if not appropriately recognized and treated preoperatively...
April 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28496539/efficacy-and-safety-of-direct-acting-oral-anticoagulants-use-in-acute-portal-vein-thrombosis-unrelated-to-cirrhosis
#4
Filipe Nery, Diana Valadares, Sara Morais, Manuel Teixeira Gomes, Andrea De Gottardi
In acute portal vein thrombosis (APVT) unrelated to cirrhosis, anticoagulant therapy is classically started with low molecular weight heparin or vitamin K antagonists. New direct-acting oral anticoagulants (DOACs) are used in the treatment of venous thrombosis outside the splanchnic vascular bed, but not in the latter. We report a young female with APVT occurring in a non-cirrhotic liver linked to heterozygosity of factor V-Leiden and prothrombin G20210A gene mutations. Rivaroxaban was started, with total recanalization of the left and partial recanalization of the right portal vein branches, without complications...
April 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28496538/iron-pill-gastritis-an-under-diagnosed-condition-with-potentially-serious-outcomes
#5
Tagore Sunkara, Megan E Caughey, Sofia Nigar, Raquel Olivo, Vinaya Gaduputi
Given the ubiquitous use of oral iron therapy, their side effects are often encountered and well recognized in clinical practice. However, iron pill gastritis remains an often under-reported and elusive diagnosis. An astute clinician should be aware of this condition in order to promptly discontinue oral iron and institute timely treatment. Here in, we present a case of a 46-year-old woman who presented to the gastroenterology clinic with vague epigastric pain and microcytic anemia. Esophagogastroduodenoscopy revealed multiple gastric erosions and non-bleeding gastric antral ulcer with biopsies showing excessive iron deposition suggestive of iron pill gastritis...
April 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28496537/post-colonoscopy-colonic-perforation-presenting-with-subcutaneous-emphysema-a-case-report
#6
Muhammad Khan, Muhammad Ijaz, Sumera Bukhari, Ahmed Dirweesh, Donald Christmas
Colonoscopy is performed for both diagnostic and therapeutic indications. Although rare, associated complications can be quite serious. The frequency of these complications depends mainly on the skills of the physicians doing the procedure, and the diagnostic or therapeutic indications. Major complications include adverse anesthetic related events, aspiration pneumonia, bleeding, and colonic perforation. We present a rare case of a post-colonoscopy perforation presenting with subcutaneous emphysema and free mediastinal, and intra-peritoneal air...
April 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28496536/percutaneous-endoscopic-gastrostomy-in-a-patient-with-continuous-intrathecal-baclofen-infusion-therapy
#7
Ezekiel Wong Toh Yoon, Masuki Kobayashi
Percutaneous endoscopic gastrostomy (PEG) is the method of choice in patients requiring long-term enteral tube feeding. In patients with intrathecal baclofen infusion therapy (IBT) pump implantation, infection via the skin and soft tissue may be an issue of concern. The introducer technique for gastrostomy tube insertion may be useful in reducing the risk of peristomal infection. Although the presence of a PEG tube has been reported as a risk factor for implantation site infection (for newly inserted IBT pumps), whether existing IBT pumps are at risk for infection during or after the placement of a PEG tube is not clear...
April 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28496535/spontaneous-rupture-of-a-choledochal-cyst-during-post-partum-a-rare-presentation
#8
Ashish Gupta, Karikal Chakaravarthi, Lileswar Kaman
With the advent of newer radiological investigations, choledochal cysts are being diagnosed more often in present era. These cysts are commonly diagnosed in early childhood and infancy, although some go undetected to be diagnosed in adulthood. These malformations are associated with multiple complications like cholangitis, jaundice, pancreatitis, rupture or even malignancy. Here we describe a post partum female, who was diagnosed to have choledochal cyst during sixth month of pregnancy. She presented with obstructive jaundice in cholangitis and was subjected to endoscopic retrograde cholangiopancreatography (ERCP) with stenting...
April 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28496534/collagenous-gastritis-in-a-young-female-with-iga-deficiency
#9
Muhammad S Anwar, Ali Aamar, Ali Marhaba, Jagmohan S Sidhu
Collagenous gastritis, without colonic involvement, is exceptionally rare. It is not known to be associated with IgA deficiency and scleroderma. This is the first report of this type of association. We present a 26-year-old white female with a past medical history of gastroesophageal reflux disease and scleroderma. She was evaluated for complaints of abdominal pain and diarrhea. Esophagogastroduodenoscopy showed gastritis and duodenitis. Colonoscopy was normal. The histopathological report showed collagenous gastritis and focal lymphocytic duodenitis...
April 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28496533/the-diagnostic-value-of-alarm-features-for-identifying-types-and-stages-of-upper-gastrointestinal-malignancies
#10
Shou-Wu Lee, Chi-Sen Chang, Hong-Jeh Yeh, Han-Chung Lien, Teng-Yu Lee, Yen-Chun Peng
BACKGROUND: Upper gastrointestinal (GI) malignancies are an uncommon cause of dyspepsia but of great concern. The aim of this study was to determine the association between alarm features and each type and stage of upper GI malignancies. METHODS: Patients who underwent endoscopy for symptoms of dyspepsia between January 2008 and December 2009 were retrospectively collected. Alarm features studied in this study were dysplasia, body weight loss and GI bleeding. Patients were classified according to the findings of endoscopy and histological reports...
April 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28496532/lack-of-association-between-the-clinical-outcome-of-clostridium-difficile-infection-and-current-steroids-use
#11
Ahmed Dirweesh, Chikezie Alvarez, Muhammad Khan, Bushra Ambreen, Rishitha Yelisetti, Shaikh Fawwad Hamiz, Sana Zia, Muhammad Tahir, Vincent A DeBari, Donald Christmas, Sara Wallach
BACKGROUND: The purpose of this study was to compare the outcome of Clostridium difficile infection (CDI) in patients on systemic steroids for various indications to patients not on steroids in term of disease severity, and associated morbidity and mortality. METHODS: We retrospectively reviewed records of all patients with CDI at our hospital from January 2011 to December 2016. Patients were evaluated for baseline characteristics, comorbidities, medications, disease severity, disease-related length of stay (LOS) from the diagnosis of CDI to discharge, need for surgical intervention, and disease-related mortality...
April 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28496531/differential-simultaneous-liver-and-kidney-transplant-benefit-based-on-severity-of-liver-damage-at-the-time-of-transplantation
#12
Shahid Habib, Khalid Khan, Chiu-Hsieh Hsu, Edward Meister, Abbas Rana, Thomas Boyer
BACKGROUND: We evaluated the concept of whether liver failure patients with a superimposed kidney injury receiving a simultaneous liver and kidney transplant (SLKT) have similar outcomes compared to patients with liver failure without a kidney injury receiving a liver transplantation (LT) alone. METHODS: Using data from the United Network of Organ Sharing (UNOS) database, patients were divided into five groups based on pre-transplant model for end-stage liver disease (MELD) scores and categorized as not having (serum creatinine (sCr) ≤ 1...
April 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28496530/assessment-of-the-relation-between-snp-in-mxa-gene-and-the-responsiveness-of-egyptian-hcv-genotype-4-patients-to-pegylated-interferon-and-ribavirin-treatment
#13
Mohamed Hassany, Amany Gamal, Nashwa Zaki, Basem Eysa
BACKGROUND: Pegylated interferon (PegIFN) is used in the treatment of chronic hepatitis C virus (HCV) patients especially in resource limited countries. Treatment with PegIFN stimulates the expression of a number of host genes encoding enzymes with antiviral activities, including myxovirus resistance gene-A (MxA gene). MxA gene was found to have a single nucleotide polymorphism (SNP) at position -88 in the promoter region that affects the expression of MxA gene protein and was suggested to affect the treatment outcome...
April 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28496529/discontinuation-of-scheduled-infliximab-in-crohn-s-patients-with-clinical-remission-a-retrospective-single-center-study
#14
Huiqin Hu, Cheng Xiang, Chen Qiu, Zhao Chen, Silin Huang, Li Liang, Xinying Wang
BACKGROUND: It is crucial to determine whether infliximab (IFX) therapy could be safely interrupted in Crohn's disease (CD) patients with clinical remission. The outcome and risk predictors of relapse after IFX therapy stopped are controversial. The aim was to assess the relapse and predictive factors after IFX discontinuation in CD patients with clinical remission. METHODS: A retrospective cohort of CD patients with clinical remission who discontinued scheduled IFX therapy at Nanfang Hospital were included...
April 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28496528/long-term-study-of-children-with-rome-iii-functional-gastrointestinal-disorders-managed-symptomatically-in-a-biopsychosocial-model
#15
Shailender Madani, Suchi Parikh, Rohit S Madani, Amornluck Krasaelap
BACKGROUND: Our study evaluated progression of and identified potential factors contributing to outcomes of ROME III defined-functional gastrointestinal disorders (FGIDs) in children treated symptomatically in a biopsychosocial model of care with a long-term follow-up. METHODS: We performed a retrospective review of pediatric patients who were diagnosed with ROME III defined-FGIDs including functional abdominal pain, functional dyspepsia, irritable bowel syndrome and abdominal migraine...
April 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28496527/correlation-between-symptom-severity-and-health-related-life-quality-of-a-population-with-gastroesophageal-reflux-disease
#16
Shou-Wu Lee, Teng-Yu Lee, Han-Chung Lien, Yen-Chun Peng, Hong-Jeh Yeh, Chi-Sen Chang
BACKGROUND: Gastroesophageal reflux disease (GERD) is a chronic disease with a negative impact on the quality of life. The aim of this study was to investigate the reflux symptoms and the health-related quality of life in a population with GERD. METHODS: Data from patients with GERD, according to the Montreal definition, were collected between January and December 2009. The enrolled patients were classified by different reflux symptoms according to the modified Chinese GERDQ...
April 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28496526/changing-trends-in-age-gender-racial-distribution-and-inpatient-burden-of-achalasia
#17
Vaibhav Wadhwa, Prashanthi N Thota, Malav P Parikh, Rocio Lopez, Madhusudhan R Sanaka
BACKGROUND: Achalasia is an idiopathic esophageal motility disorder characterized by dysphagia, regurgitation, chest discomfort and weight loss. The aim of this study was to evaluate the temporal trends in demographic variables, interventions, and inpatient burden in achalasia-related hospitalizations. METHODS: We evaluated the National Inpatient Sample Database (NIS) for all patients in whom achalasia (ICD-9 code: 530.0) was the principal discharge diagnosis from 1997 to 2013...
April 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28496525/il-10-and-il-10-receptor-mutations-in-very-early-onset-inflammatory-bowel-disease
#18
REVIEW
Lei Zhu, Tingting Shi, Chengdi Zhong, Yingde Wang, Michael Chang, Xiuli Liu
Very early onset inflammatory bowel disease (VEO-IBD) is a unique disease entity with a complex genetic susceptibility in affected patients. Next-generation gene sequencing techniques have revealed various monogenetic mutations contributing to the pathogenesis of VEO-IBD, including interleukin 10 (IL-10) and IL-10 receptor (IL-10R) mutations. In this article, we reviewed the features of and effective therapeutic options for VEO-IBD with IL-10 and/or IL-10R mutations. The IL-10 signal pathway inhibits the release of several key cytokines and thereby has a significant anti-inflammatory effect in the gastrointestinal tract...
April 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28270881/intestinal-injury-associated-with-uterine-perforation-due-to-surgical-abortion-in-japan
#19
Shunji Suzuki
No abstract text is available yet for this article.
February 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28270880/colonic-endometriosis-dig-deeper-for-diagnosis
#20
Kanthi Rekha Badipatla, Anisha Vupputuri, Masooma Niazi, Marie-Nirva Blaise, Suresh Kumar Nayudu
Endometriosis is a common gynecological condition wherein there is an ectopic implantation of the uterine endometrial tissue. While several diagnostic modalities are described for the condition, laparoscopy remains the gold standard. There is still an undiscovered area to diagnose colonic endometriosis at an earlier stage. We present a case report of a reproductive age woman with cyclical rectal bleeding diagnosed with colonic endometriosis with colonoscopy and biopsy using saline injection lift and sampling technique...
February 2017: Gastroenterology Research
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