Houssein H Ayoub, Hiam Chemaitelly, Monia Makhoul, Zaina Al Kanaani, Einas Al Kuwari, Adeel A Butt, Peter Coyle, Andrew Jeremijenko, Anvar Hassan Kaleeckal, Ali Nizar Latif, Riyazuddin Mohammad Shaik, Hanan F Abdul Rahim, Gheyath K Nasrallah, Hadi M Yassine, Mohamed G Al Kuwari, Hamad Eid Al Romaihi, Mohamed H Al-Thani, Roberto Bertollini, Abdullatif Al Khal, Laith J Abu-Raddad
Background: Vaccines against SARS-CoV-2 have been developed, but their availability falls far short of global needs. This study aimed to investigate the impact of prioritising available doses on the basis of recipient antibody status, that is by exposure status, using Qatar as an example. Methods: Vaccination impact (defined as the reduction in infection incidence and the number of vaccinations needed to avert one infection or one adverse disease outcome) was assessed under different scale-up scenarios using a deterministic meta-population mathematical model describing SARS-CoV-2 transmission and disease progression in the presence of vaccination...
April 2021: BMJ Innovations