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Journal of Audiology & Otology

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https://www.readbyqxmd.com/read/29301392/clinical-safety-and-efficacy-of-autologous-bone-marrow-derived-mesenchymal-stem-cell-transplantation-in-sensorineural-hearing-loss-patients
#1
Ho Seok Lee, Woo Jin Kim, Ji Sun Gong, Kyoung Ho Park
Stem cell transplantation represents a promising therapy for several degenerating and necrotic diseases. In several animal studies, we could find hearing restoration after inoculation of the mesenchymal stem cells' as well as mesenchymal stem cells' differentiation of hair cells and spiral ganglion. But until now, no clinical study has been reported directly for the human being. In this pilot studies, we applied mesenchymal stem cells to human beings trans-venously. Although we verified the safety of the autologous bone marrow stem cell transplantation in sensorineural hearing loss patients but we could not achieve significant improvement in hearing...
January 5, 2018: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/29301391/locacorten-vioform-ototoxicity-upon-guinea-pig-middle-ear-application
#2
Owen Woods, Issam Saliba
Background and Objectives: Locacorten Vioform (Novartis UK) is frequently prescribed for otomycosis. Its component, Clioquinol, also has anti-bacterial properties. Up to this point, its ototoxic potential has not been evaluated. Our objective aims to evaluate Locacorten Vioform's potential ototoxicity when applied directly to the middle ear cavity. Materials and Methods: We performed an experimental prospective animal study in our animal research center with 20 Hartley guinea pigs divided into 2 groups...
January 5, 2018: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/29301390/acoustic-features-and-cortical-auditory-evoked-potentials-according-to-emotional-statues-of-u-a-i-vowels
#3
Chunhyeok Kim, Seungwan Lee, Inki Jin, Jinsook Kim
Background and Objectives: Although Ling 6 sounds are often used in the rehabilitation process, its acoustic features have not been fully analyzed and represented in cortical responses. Current study was aimed to analyze acoustic features according to gender and emotional statuses of core vowels of Ling 6 sounds, /u/, /a/, and /i/. Cortical auditory evoked potentials (CAEPs) were also observed in those vowels. Subjects and Methods: Vowel sounds /u/, /a/, and /i/ out of Ling 6 sounds representing low, middle and high frequencies were recorded from normal 20 young adults...
January 5, 2018: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/29301389/the-effect-of-primary-levels-and-frequencies-on-the-contralateral-suppression-of-distortion-product-otoacoustic-emission
#4
Natalia Yakunina, Jinsook Kim, Eui-Cheol Nam
Background and Objectives: Changes in distortion product otoacoustic emission (DPOAE) caused by contralateral suppression (CS) allow the function of the auditory efferent system to be evaluated. Parameters affording maximum CS are preferred in terms of clinical application. Our objective was to evaluate the effects of primary levels and frequencies on DPOAEmediated CS. Subjects and Methods: Sixteen subjects with normal hearing participated. DPOAEs were recorded with and without contralateral acoustic stimulation; we delivered broadband noise of 65 dB SPL at f2 frequencies between 1,000 Hz and 6,727 Hz, at 8 pt/ octave...
January 5, 2018: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/29325393/role-of-emotional-distress-in-prolongation-of-dizziness-a-cross-sectional-study
#5
Kyung Jin Roh, Min Ki Kim, Ji Hyung Kim, Eun Jin Son
BACKGROUND AND OBJECTIVES: Dizziness is a common condition in outpatient clinics. Comorbid conditions such as anxiety and/or depression often complicate a patient's ability to cope with dizziness. The purpose of the present study was to explore the extent of psychiatric distress using the Hospital Anxiety and Depression Scale (HADS) and to compare the results with the subjective severity of dizziness. SUBJECTS AND METHODS: The cross-sectional study included a total of 456 consecutive patients presenting with acute (n=327) and chronic (n=127) dizziness symptoms...
December 2017: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/29325392/horizontal-localization-in-simulated-unilateral-hearing-loss
#6
Anvarsamarein Parisa, Nazeri Ahmad Reza, Sameni Seyyed Jalal, Kamali Mohammad, Zarrin Koob Homa
BACKGROUND AND OBJECTIVES: The ability to localize a sound source is one of the binaural hearing benefits in a horizontal plane based on interaural time difference and interaural intensity difference. Unilateral or bilateral asymmetric hearing loss will affect binaural hearing and lead to sound locating errors. In this cross sectional analytical descriptive study, the localization error was investigated when participants turned their heads to the sound source with closed eyes and after simulating unilateral hearing loss by placing earplugs inside the right ear canal...
December 2017: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/29325391/frequency-limiting-effects-on-speech-and-environmental-sound-identification-for-cochlear-implant-and-normal-hearing-listeners
#7
Son-A Chang, Jong Ho Won, HyangHee Kim, Seung-Ha Oh, Richard S Tyler, Chang Hyun Cho
BACKGROUND AND OBJECTIVES: It is important to understand the frequency region of cues used, and not used, by cochlear implant (CI) recipients. Speech and environmental sound recognition by individuals with CI and normal-hearing (NH) was measured. Gradients were also computed to evaluate the pattern of change in identification performance with respect to the low-pass filtering or high-pass filtering cutoff frequencies. SUBJECTS AND METHODS: Frequency-limiting effects were implemented in the acoustic waveforms by passing the signals through low-pass filters (LPFs) or high-pass filters (HPFs) with seven different cutoff frequencies...
December 2017: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/29325390/translation-adaptation-and-cross-language-validation-of-tinnitus-handicap-inventory-in-urdu
#8
Muhammad Aqeel, Ammar Ahmed
BACKGROUND AND OBJECTIVES: Tinnitus is characterized as a perception of numerous auditory sounds in absence of external stimulus. Tinnitus can have a considerable consequence on a person's quality of life, and is considered to be very complicated to quantify. The aim of this study was to investigate the reliability and validity of Urdu translation of the Tinnitus Handicap Inventory (THI) in Pakistan. It was designed to assess the presence of various auditory sounds without the external stimulus...
December 2017: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/29061035/the-effect-of-ethnicity-on-wideband-absorbance-of-neonates-with-healthy-middle-ear-functions-in-malaysia-a-preliminary-study
#9
Hamzah A Wali, Rafidah Mazlan
Background and Objectives: Ethnicity effect on wideband absorbance (WBA) findings was evident in adults. However, its effect on neonates has not been established yet. This study aimed to investigate the influence of ethnicity on WBA measured at 0 daPa from neonates with healthy middle ear functions. Subjects and Methods: Participants were 99 normal, healthy, full-term newborn babies with chronological age between 11 and 128 hours of age (mean=46.73, standard deviation=26...
October 24, 2017: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/29061034/the-light-cupula-an-emerging-new-concept-for-positional-vertigo
#10
Min-Beom Kim, Seok Min Hong, Hyerang Choi, Seongjun Choi, Ngoc Chien Pham, Jung Eun Shin, Chang-Hee Kim
Benign paroxysmal positional vertigo (BPPV) is the most common type of positional vertigo. A canalolithiasis-type of BPPV involving the lateral semicircular canal (LSCC) shows a characteristic direction-changing positional nystagmus (DCPN) which beats towards the lower ear (geotropic) on turning the head to either side in a supine position. Because geotropic DCPN in LSCC canalolithiasis is transient with a latency of a few seconds, the diagnosis can be challenging if geotropic DCPN is persistent without latency...
October 24, 2017: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/29036759/can-a-sudden-sensorineural-hearing-loss-occur-due-to-miliary-tuberculosis
#11
Sang-Ki Min, Ji-Ho Shin, Seog-Kyun Mun
Miliary tuberculosis is a severe form of tuberculosis resulting from dissemination of Mycobacterium tuberculosis bacilli. Since symptoms appearing in patients due to miliary TB are diverse and atypical, depending on the site of invasion, early diagnosis and treatment are important. A paradoxical response of tuberculosis is a rare phenomenon and it can be a clinical difficulty to treatment especially when involving the central nervous system. We present a case report with a review of related literature about the patient who developed sudden hearing loss due to tuberculosis infection in vestibulocochlear area...
October 17, 2017: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/29036758/comparison-of-single-task-versus-dual-task-for-listening-effort
#12
Chanbeom Kwak, Woojae Han
Background and Objectives: Depending on the kind of task and/or material, listeners sometimes need to pay attention to understand communication. The present study aimed to estimate a listener's amount of effort needed to understand communication by using recognition score and response time as a function of signal-to-noise ratio (SNR) and to confirm his/ her task dependency for listening effort. Subjects and Methods: Forty-eight young adults with normal hearing participated in the study...
October 17, 2017: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/29036757/a-case-of-medullary-infarction-presented-initial-symptoms-similar-to-meniere-s-disease
#13
Jang Hee Park, Dong Hyun Kim, Jae Moon Sung, Chang Woo Kim
Fluctuating hearing loss and vertigo are the typical presentations of Meniere's disease. However, it is unusual that fluctuating hearing loss and vertigo are caused by vertebral artery occlusion or cerebral infarction. Here, we described the case of a 54-year-old male patient with hypertension and diabetes mellitus who presented with fluctuating hearing loss in his left ear and severe whirling-type dizziness without associated neurological signs or symptoms. Temporal magnetic resonance imaging (MRI) was normal...
October 17, 2017: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/28942633/blind-sac-approach-using-silastic-block-for-cochlear-implantation-in-patients-with-cholesteatoma
#14
Ah-Ra Lyu, Yong-Ho Park
Cochlear implant (CI) surgery in cholesteatoma is challenging because of the risk of residual or recurrent infection. Although CI could be done with subtotal petrosectomy in single or staged surgery, this surgery needed additional surgical procedures to obliterate the mastoid cavity. This paper describes a new surgical technique for CI surgery in cholesteatoma without external auditory canal closure.
September 2017: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/28942632/neuropharmacological-targets-for-drug-action-in-vestibular-sensory-pathways
#15
REVIEW
Choongheon Lee, Timothy A Jones
The use of pharmacological agents is often the preferred approach to the management of vestibular dysfunction. In the vestibular sensory pathways, the sensory neuroepithelia are thought to be influenced by a diverse number of neuroactive substances that may act to enhance or inhibit the effect of the primary neurotransmitters [i.e., glutamate (Glu) and acetylcholine (ACh)] or alter their patterns of release. This review summarizes various efforts to identify drug targets including neurotransmitter and neuromodulator receptors in the vestibular sensory pathways...
September 2017: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/28942631/the-changing-pattern-of-published-articles-in-the-field-of-otology-1818-to-today
#16
Jang Hee Park, Janet Ren Chao, Min Jae Kim, Yoo Yeon Kim, Jun Ho Lee
To examine and identify the changing pattern of published articles in the otology literature over the past several decades. We used a variety of search engines available through PubMed.gov based on key words in the following categories: diagnosis, diagnostic tools, and therapeutic tools. The number of searchable key words increased from 1945 to the present. Overall, there has been a major shift in topics cover in the otological literature. Most recently, there has been significant increases in the following categories: age-related hearing loss, speech discrimination, and cochlear implantation...
September 2017: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/28942630/effect-of-vowel-context-on-the-recognition-of-initial-consonants-in-kannada
#17
Mohan Kumar Kalaiah, Jayashree S Bhat
BACKGROUND AND OBJECTIVES: The present study was carried out to investigate the effect of vowel context on the recognition of Kannada consonants in quiet for young adults. SUBJECTS AND METHODS: A total of 17 young adults with normal hearing in both ears participated in the study. The stimuli included consonant-vowel syllables, spoken by 12 native speakers of Kannada. Consonant recognition task was carried out as a closed-set (fourteen-alternative forced-choice)...
September 2017: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/28942629/multiple-dural-arteriovenous-fistulas-presenting-as-pulsatile-tinnitus-treated-with-external-manual-compression
#18
Se-Joon Oh, Yong-Il Chon, Soo-Keun Kong, Eui-Kyung Goh
Dural arteriovenous fistula (DAVF) have been treated by transarterial or transvenous embolization, surgery, and radiosurgery. Besides these treatment options, the external compression technique is a non-invasive, low-cost form of treatment. This article reports that a 60-year-old man with DAVF between multiple arterial branches and transverse/sigmoid sinus was treated by repeated external manual compression method.
September 2017: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/28942628/postoperative-mastoid-aeration-following-canal-wall-up-mastoidectomy-according-to-preoperative-middle-ear-disease-analysis-of-temporal-bone-computed-tomography-scans
#19
Oh Joon Kwon, Jae Moon Sung, Hwi Kyeong Jung, Chang Woo Kim
BACKGROUND AND OBJECTIVES: The aim of our study was to evaluate postoperative mastoid aeration according to the preoperative middle ear disease and investigate the factors affecting it. SUBJECTS AND METHODS: We retrospectively reviewed the high-resolution computed tomography (CT) scans of temporal bones that were taken 1 year after surgery. The postoperative mastoid aeration was evaluated according to the preoperative diagnosis, and classified into three groups: grade 1 (complete mastoid aeration), an air-filled epitympanum and mastoid cavity; grade 2 (partial mastoid aeration), an air-filled epitympanum and partially aerated mastoid cavity; and grade 3 (absence of mastoid aeration), no air space in the mastoid cavity...
September 2017: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/28942627/preferred-compression-threshold-and-release-time-in-quiet-and-noisy-conditions-for-elderly-korean-hearing-aid-users
#20
Woojae Han, Junghak Lee, Jinsook Kim, Kyeongwon Lee, Dongwook Kim
BACKGROUND AND OBJECTIVES: Listeners with sensorineural hearing loss want to compensate for their narrow dynamic range from appropriate compression functions of hearing aids. The present study aimed to determine which compression threshold and release time of nonlinear hearing aids might affect speech recognition and speech quality judgments. SUBJECTS AND METHODS: Ten elderly listeners with symmetrical moderate-to-severe sensorineural hearing loss participated in the study...
September 2017: Journal of Audiology & Otology
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