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Journal of Virus Eradication

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https://www.readbyqxmd.com/read/29057093/bone-mineral-density-optimisation-in-adults-with-perinatally-acquired-hiv-infection-in-routine-care
#1
EDITORIAL
Thomas J Pasvol, Fred Fyles, Caroline Foster, Sarah Fidler
No abstract text is available yet for this article.
October 1, 2017: Journal of Virus Eradication
https://www.readbyqxmd.com/read/29057092/highlights-from-the-9-th-international-workshop-on-pediatrics-21-22-july-2017-paris-france
#2
EDITORIAL
(no author information available yet)
No abstract text is available yet for this article.
October 1, 2017: Journal of Virus Eradication
https://www.readbyqxmd.com/read/29057091/highlights-from-the-bhiva-satellite-symposium-ias-conference-paris-france-july-2017-tougher-times-adapting-to-increasing-demand-with-declining-resources
#3
EDITORIAL
(no author information available yet)
No abstract text is available yet for this article.
October 1, 2017: Journal of Virus Eradication
https://www.readbyqxmd.com/read/29057090/highlights-from-the-9th-ias-conference-on-hiv-science-23-26-july-2017-paris-france
#4
EDITORIAL
Christina K Psomas, Tristan J Barber, Sofie Rutsaert, Sabine Kinloch-de Loës
No abstract text is available yet for this article.
October 1, 2017: Journal of Virus Eradication
https://www.readbyqxmd.com/read/29057089/converging-roads-the-latest-science-from-the-2017-ias-hiv-cure-and-cancer-forum
#5
EDITORIAL
Genevieve E Martin, José Alcami, Jean-Phillipe Spano, Anna Laura Ross
No abstract text is available yet for this article.
October 1, 2017: Journal of Virus Eradication
https://www.readbyqxmd.com/read/29057088/hiv-cure-research-print-and-online-media-reporting-in-australia
#6
EDITORIAL
Jennifer Power, Bianca Fileborn, Gary W Dowsett, Jayne Lucke, Graham Brown, Jeanne Ellard, Sharon R Lewin, Joseph D Tucker, Sean Slavin, Jeremy Sugarman, Sophie Hill
OBJECTIVES: While still in its early stages, recent scientific research towards a cure for HIV has generated widespread media interest. The aim of this paper was to explore the ways in which this research has been represented in Australian print and online media and discuss implications of this. METHODS: A search of databases from four selected media outlets was conducted to identify published articles that directly discussed HIV cure research. Content analysis was used to explore the discursive framing of HIV cure research and identify the presence or absence of people living with HIV in articles...
October 1, 2017: Journal of Virus Eradication
https://www.readbyqxmd.com/read/29057087/hiv-cure-research-community-engagement-in-north-carolina-a-mixed-methods-evaluation-of-a-crowdsourcing-contest
#7
EDITORIAL
Allison Mathews, Samantha Farley, Meredith Blumberg, Kimberley Knight, Lisa Hightow-Weidman, Kate Muessig, Stuart Rennie, Joseph Tucker
OBJECTIVES: The purpose of this study was to evaluate the feasibility of using a crowdsourcing contest to promote HIV cure research community engagement. METHODS: Crowdsourcing contests are open calls for community participation to achieve a task, in this case to engage local communities about HIV cure research. Our contest solicited images and videos of what HIV cure meant to people. Contestants submitted entries to IdeaScale, an encrypted online contest platform...
October 1, 2017: Journal of Virus Eradication
https://www.readbyqxmd.com/read/29057086/interprep-internet-based-pre-exposure-prophylaxis-with-generic-tenofovir-df-emtricitabine-in-london-an-analysis-of-outcomes-in-641-patients
#8
EDITORIAL
Isaac Aloysius, Anna Savage, Jey Zdravkov, Roxanna Korologou-Linden, Andrew Hill, Rachel Smith, Vicky Houghton-Price, Marta Boffito, Nneka Nwokolo
INTRODUCTION: HIV pre-exposure prophylaxis (PrEP) is not available on the National Health Service (NHS) in England. People are buying generic versions of tenofovir disoproxil fumarate (TDF)/emtricitabine (FTC) on the internet, which is legal under UK import laws. METHODS: HIV-negative individuals attending our clinic who reported purchasing generic PrEP online were provided with risk-reduction advice and were evaluated for HIV, hepatitis B and C, renal function and sexually transmitted infections (STIs)on their first visit...
October 1, 2017: Journal of Virus Eradication
https://www.readbyqxmd.com/read/29057085/the-evaluation-of-risk-benefit-ratio-for-gut-tissue-sampling-in-hiv-cure-research
#9
EDITORIAL
Vikram Mehraj, Peter Ghali, Rayoun Ramendra, Cecilia Costiniuk, Bertrand Lebouché, Rosalie Ponte, Robert Reinhard, Jose Sousa, Nicolas Chomont, Eric A Cohen, Petronela Ancuta, Jean-Pierre Routy
INTRODUCTION: Antiretroviral therapy (ART) does not cure HIV infection due to the persistence of HIV reservoirs in long-lived memory CD4 T cells present in the blood, lymph nodes, intestinal tract, and other tissues. Interest grows in obtaining gut-tissue samples for HIV persistence studies, which poses an ethical challenge to provide study volunteers with adequate information on risks and benefits. Herein we assess the risks and benefits of undergoing gut biopsy procedures for HIV pathogenesis and reservoir studies...
October 1, 2017: Journal of Virus Eradication
https://www.readbyqxmd.com/read/29057084/changes-in-the-haematological-parameters-of-hiv-1-infected-children-at-6-and-12-months-of-antiretroviral-therapy-in-a-large-clinic-cohort-north-central-nigeria
#10
EDITORIAL
Augustine O Ebonyi, Stephen Oguche, Martha O Ochoga, Oche O Agbaji, Joseph A Anejo-Okopi, Isaac O Abah, Prosper I Okonkwo, John A Idoko
BACKGROUND: Prior to commencing antiretroviral therapy (ART), haematological abnormalities are a common occurrence in individuals diagnosed with human immunodeficiency virus (HIV). In the course of receiving ART, these abnormalities usually improve. We determined the prevalence of haematological abnormalities in children diagnosed with HIV-1 and the changes in haematological parameters that occur after 6 and 12 months of being on ART. METHODS: A cross-sectional study of HIV-1 infected children aged 2 months to 15 years, between July 2005 and March 2013, at the paediatric HIV clinic of the Jos University Teaching Hospital, Jos...
October 1, 2017: Journal of Virus Eradication
https://www.readbyqxmd.com/read/29057083/low-level-genital-hiv-shedding-in-thai-hiv-infected-women-with-suppressed-plasma-viral-load-after-menopause-a-longitudinal-study
#11
EDITORIAL
Nadia Kancheva Landolt, Tanya Do, Naruporn Kasipong, Rosalin Kriengsinyot, Sasiwimol Ubolyam, Apicha Mahanontharit, Tippawan Pankam, Tanakorn Apornpong, Anchalee Avihingsanon, Jintanat Ananworanich, Nittaya Phanuphak, Surasith Chaithongwongwatthana
OBJECTIVES: First, to evaluate the longitudinal changes of HIV RNA in genital secretions in HIV-positive women with plasma HIV RNA <50 copies/mL before and after the onset of menopause. Second, to assess inflammatory markers and prevalence of comorbidities after the onset of menopause. METHODS: This was a prospective observational study with two time points. HIV RNA in genital secretions (GVL) was measured in 15 HIV-positive menopausal women (second time point)...
October 1, 2017: Journal of Virus Eradication
https://www.readbyqxmd.com/read/29057082/high-sustained-virological-response-rates-using-imported-generic-direct-acting-antiviral-treatment-for-hepatitis-c
#12
EDITORIAL
Andrew Hill, Giten Khwairakpam, James Wang, Sergey Golovin, Julia Dragunova, Rachel Smith, Vicky Houghton-Price, Roxanna Korologou-Linden, Sanjay Nath, Anna Savage, Greg Jefferys
BACKGROUND: High prices of direct acting antivirals (DAAs) for hepatitis C virus (HCV) can lead to restrictions on access to treatment in high- and middle-income countries. An increasing number of people in these countries are treating their HCV infection with generic drugs produced in India, China, Bangladesh or Egypt. This analysis assessed the efficacy of generic imported DAAs. METHODS: Patients sourced generic versions of sofosbuvir (SOF), ledipasvir (LDV) and daclatasvir (DCV) from suppliers in India, Bangladesh, China and Egypt via three buyers' clubs...
October 1, 2017: Journal of Virus Eradication
https://www.readbyqxmd.com/read/29057081/the-challenges-of-ending-aids-in-asia-outcomes-of-the-thai-national-aids-universal-coverage-programme-2000-2014
#13
EDITORIAL
Suchada Chaivooth, Sorakij Bhakeecheep, Kiat Ruxrungtham, Sirinya Teeraananchai, Stephen J Kerr, Achara Teeraratkul, Petchsri Sirinirund, Sumet Ongwandee, Anchalee Avihingsanon, Patchara Benjarattanaporn, Nittaya Phanuphak, Somnuek Sungkanuparph, Sophon Mekthon, Praphan Phanuphak
OBJECTIVES: We sought to determine Thai National AIDS Program (NAP) outcomes and gaps, and success in reaching the WHO 90:90:90 goals. METHODS: Retrospective study of treatment outcomes, mortality and loss to follow-up (LTFU), of all individuals aged >15 years who registered to the NAP from 2000 to 2014. We focused outcomes on data from 2008 when the NAP was linked to the death registry. RESULTS: A total of 429,294 patients registered to the NAP up to November 2014, and 309,313 patients aged >15 years started ART...
October 1, 2017: Journal of Virus Eradication
https://www.readbyqxmd.com/read/29057080/the-role-of-mir-29a-in-hiv-1-replication-and-latency
#14
EDITORIAL
Giacomo Frattari, Lars Aagaard, Paul W Denton
The development of an effective HIV-1 eradication strategy relies upon a clear understanding of the cellular mechanisms involved in HIV-1 latency. Among such cellular processes, microRNA activities affect HIV-1 production by regulating viral transcripts as well as host cell HIV-1 dependency factors. miR-29a stands apart from other relevant microRNAs as a potential therapeutic target in HIV-1 eradication. In vitro experiments have shown that miR-29a binds to a sequence in the 3'UTR of viral transcripts and inhibits their expression...
October 1, 2017: Journal of Virus Eradication
https://www.readbyqxmd.com/read/29057094/oral-abstracts-of-the-hiv-cure-and-reservoir-symposium-2017
#15
EDITORIAL
(no author information available yet)
No abstract text is available yet for this article.
September 11, 2017: Journal of Virus Eradication
https://www.readbyqxmd.com/read/28758027/australasian-society-for-hiv-viral-hepatitis-and-sexual-health-medicine-hiv-pre-exposure-prophylaxis-clinical-guidelines
#16
EDITORIAL
Edwina Wright, Andrew Grulich, Katy Roy, Mark Boyd, Vincent Cornelisse, Darren Russell, Darryl O'Donnell, Bill Whittaker, Levinia Crooks, Iryna Zablotska
Daily use of coformulated tenofovir and emtricitabine for HIV pre-exposure prophylaxis (PrEP) by populations at high risk of HIV infection is now recommended in guidelines from the United States, Europe and Australia and globally through the 2015 WHO guidelines. These 2017 Australasian Society for HIV, Viral Hepatitis and Sexual Health Medicine's (ASHM) PrEP Guidelines are an updated adaptation of the 2014 US Centers for Disease Control's PrEP guidelines and are designed to: •Support the prescription of PrEP using forms of coformulated tenofovir and emtricitabine that have been registered in Australia by the Therapeutic Goods Administration and other bioequivalent generic drugs that are available in Australia through self-importation, private prescription or Australian PrEP clinical trials•Assist clinicians in the evaluation of patients who are seeking PrEP•Assist clinicians in commencing and monitoring patients on PrEP including PrEP dosing schedules, management of side-effects and toxicity, use of PrEP in pregnancy and in chronic hepatitis B infection and how to cease PrEP Daily PrEP with co-formulated tenofovir and emtricitabine, used continuously or for shorter periods of time, is recommended in these guidelines as a key HIV-prevention option for men who have sex with men (MSM), transgender men and women, heterosexual men and women, and people who inject drugs (PWID) at substantial risk of HIV acquisition...
July 1, 2017: Journal of Virus Eradication
https://www.readbyqxmd.com/read/28758026/scaling-up-hiv-self-testing-in-china-and-africa
#17
EDITORIAL
Joseph D Tucker, J Ong, D Conserve, S Pan, W Tang
No abstract text is available yet for this article.
July 1, 2017: Journal of Virus Eradication
https://www.readbyqxmd.com/read/28758025/pursuing-ethical-coherence-in-the-prevention-of-vertical-transmission-of-hiv-justice-and-injustice-in-option-b
#18
EDITORIAL
Nathan Hodson, Susan Bewley
Improved prevention of vertical transmission of HIV is an essential part of the global response to HIV. The Option B+ strategy took the extraordinary step of treating many non-pregnant women living with HIV (those with CD4 cell counts >350 cells/mm(3)) in the absence of evidence that they themselves would benefit from ART. This example of so-called AIDS exceptionalism reflects an understanding that the global response to HIV demands a different set of morals. This philosophical article explores a retrospective analysis of the ethical arguments made in support of Option B+ incorporating utilitarian, feminist and equity-based frameworks...
July 1, 2017: Journal of Virus Eradication
https://www.readbyqxmd.com/read/28758024/serum-lipid-and-glucose-profiles-in-hiv-positive-nigerian-children
#19
EDITORIAL
Olukemi O Ige, Christopher S Yilgwan, Augustine O Ebonyi, Ruth Adah, Idris Adedeji, Esther S Yiltok, Stephen Oguche, Fidelia Bode-Thomas
OBJECTIVES: To describe the fasting serum lipid and glucose profiles of HIV-positive Nigerian children and determine the prevalence and risk factors for dyslipidaemia and hyperglycaemia, which are risk factors for cardiovascular diseases. METHODS: This was a comparative cross-sectional study carried out at the Paediatric Infectious Disease Clinic (PIDC) of the Jos University Teaching Hospital (JUTH) for HIV-positive children and at two primary schools in Jos for HIV-negative children as controls...
July 1, 2017: Journal of Virus Eradication
https://www.readbyqxmd.com/read/28758023/strategies-to-improve-the-uptake-of-effective-contraception-in-perinatally-hiv-infected-adolescents
#20
EDITORIAL
Nadia Kancheva Landolt, Jullapong Achalapong, Pope Kosalaraksa, Witaya Petdachai, Chaiwat Ngampiyaskul, Stephen Kerr, Pongrak Boonyanurak, Jintanat Ananworanich, Torsak Bunupuradah
OBJECTIVE: To assess strategies to improve safe-sex practices in sexually active female adolescents living with HIV, through linking reproductive health (RH) care with HIV care. METHODS: A single arm, 48-week prospective study was conducted with 77 sexually active adolescents in five sites in Thailand. Guided RH education was carried out through video, brochures and individual counselling. Participants were offered free effective contraception (EC), in addition to a barrier method (dual contraception) versus barrier method only...
July 1, 2017: Journal of Virus Eradication
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