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Anatolian Journal of Cardiology

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https://www.readbyqxmd.com/read/28315571/the-relationship-of-micronucleus-frequency-and-nuclear-division-index-with-coronary-artery-disease-syntax-and-gensini-scores
#1
Emrah İpek, Emrah Ermiş, Handan Uysal, Halit Kızılet, Selami Demirelli, Erkan Yıldırım, Sedat Ünver, Bircan Demir, Nergiz Kızılet
OBJECTIVE: We aimed to evaluate the relationship of micronucleus (MN) frequency and nuclear division index (NDI) with SYNTAX and Gensini scores and thrombolysis in myocardial infarction (TIMI) frame counts of coronary arteries in patients undergoing coronary angiography. METHODS: In a single-center prospective observational study, a total of 63 individuals, 48 consecutive patients with coronary artery disease (CAD) and 15 healthy people were included. Before coronary angiography (exposure to X-ray), blood samples were collected for lymphocyte cultures, MN and NDI measurements...
March 9, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28315570/tp-e-interval-and-tp-e-qtc-ratio-as-novel-surrogate-markers-for-prediction-of-ventricular-arrhythmic-events-in-hypertrophic-cardiomyopathy
#2
Mehmet Kadri Akboğa, Kevser Gülcihan Balcı, Samet Yılmaz, Selahattin Aydın, Çağrı Yayla, Ahmet Göktuğ Ertem, Sefa Ünal, Mustafa Mücahit Balcı, Yücel Balbay, Dursun Aras, Serkan Topaloğlu
OBJECTIVE: Hypertrophic cardiomyopathy (HCM) as a common genetic heart disease characterized by ventricular hypertrophy and myocardial fibrosis is significantly associated with a higher risk of fatal ventricular arrhythmic events (VAEs). We aimed to assess the interval between the peak and the end of the electrocardiographic T wave (Tp-e) and Tp-e/corrected QT (QTc) ratio as candidate markers of ventricular arrhythmias in patients with HCM. METHODS: In this single-center, prospective study, a total of 66 patients with HCM and 88 controls were enrolled...
March 9, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28315569/algorithm-for-predicting-chd-death-risk-in-turkish-adults-conventional-factors-contribute-only-moderately-in-women
#3
Altan Onat, Günay Can, Ayşem Kaya, Muhammed Keskin, Mert I Hayıroğlu, Hüsniye Yüksel
OBJECTIVE: To assist the management strategy of individuals, we determined an algorithm for predicting the risk of coronary heart disease (CHD) death in Turkish adults with a high prevalence of metabolic syndrome (MetS). METHODS: The risk of CHD death was estimated in 3054 middle-aged adults, followed over 9.08±4.2 years. Cox proportional hazard regression was used to predict risk. Discrimination was assessed using C-statistics. RESULTS: CHD death was identified in 233 subjects...
March 9, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28315568/diurnal-blood-pressure-parameters-in-normal-tension-glaucoma-primary-open-angle-glaucoma-and-healthy-subjects
#4
Tolga Kocatürk, Çağdaş Akgüllü, Gökhan E Evliçoğlu, İmran K Ömürlü, Harun Çakmak, Ufuk Eryılmaz, Volkan Dayanır
OBJECTIVE: The pathophysiology of glaucoma is still undisclosed. Cardiovascular hemodynamic changes are hypothesized to contribute to glaucoma. This study aimed to determine the differences in the diurnal blood pressure (BP) of patients with normal tension glaucoma (NTG), primary open angle glaucoma (POAG), and controls without glaucoma. METHODS: A total of 129 patients were included in this study. The day-night average systolic and diastolic BPs, the day-night average pulse pressures (PPs), the day-night average heart rates, and the percentage of BP decline at night were obtained from the Holter devices and compared...
March 9, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28315567/a-practical-guide-for-building-a-highway-between-atria-during-transseptal-puncture-without-radiation
#5
Yuan Yuan, Deyong Long, Caihua Sang, Ling Tao, Jianzeng Dong, Changsheng Ma
OBJECTIVE: To investigate whether switching the ablation catheter between the right and left atria through transseptal puncture site can be accurately performed without fluoroscopy. METHODS: Forty patients with persistent atrial fibrillation (mean age, 60.2±7.4 years; 65% males) got "2C3L" approach were randomized in a 1:1 ratio to undergo either crossing interatrial septum guided by fluoroscopy (trackless group) or crossing septum guided by track image that was mapped by Carto3 system (track group)...
March 9, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28315565/heart-rate-variability-in-normal-weight-patients-with-polycystic-ovary-syndrome
#6
Celal Kilit, Türkan Paşalı Kilit
OBJECTIVE: Polycystic ovary syndrome (PCOS) is an endocrine disease closely related to several risk factors of cardiovascular disease. Obese women with PCOS show altered autonomic modulation. The results of studies investigating cardiac autonomic functions of normal-weight women with PCOS are conflicting. The aim of the study was to assess the reactivity of cardiac sympathovagal balance in normal-weight women with PCOS by heart rate variability analysis. METHODS: We examined the heart rate variability in 60 normal-weight women with PCOS and compared them with that in 60 age-matched healthy women having a similar metabolic profile...
March 9, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28315564/clinical-risk-scores-predict-procedural-complications-of-primary-percutaneous-coronary-intervention
#7
László Hadadi, Razvan Constantin Şerban, Alina Scridon, Ioana Şuş, Éva Katalin Lakatos, Zoltán Demjén, Dan Dobreanu
OBJECTIVE: The predictive value of five risk score models containing clinical (PAMI-PMS, GRACE-GRS, and modified ACEF-ACEFm-scores), angiographic SYNTAX score (SXS) and combined Clinical SYNTAX score (CSS) variables were evaluated for the incidence of three procedural complications of primary percutaneous coronary intervention (pPCI): iatrogenic coronary artery dissection, angiographically visible distal embolization and angiographic no-reflow phenomenon. METHODS: The mentioned scores and the incidence of procedural complications were retrospectively analyzed in 399 consecutive patients with acute ST-elevation myocardial infarction who underwent pPCI...
March 9, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28315563/impact-of-serum-erythropoietin-level-on-collateral-vessel-development-in-patients-with-coronary-artery-disease
#8
Nil Özyüncü, Sadi Güleç, Çağdaş Özdöl, Başar Candemir, Aydan Ongun, Cansın Tulunay Kaya, Çetin Erol
OBJECTIVE: Experimental data have shown that Erythropoietin (EPO) stimulates angiogenesis and neovascularization which may result in improved collateral development. The aim of this study was to investigate the association between serum EPO levels and the extent of coronary collaterals. Patient characteristics possibly related with coronary collaterals were also sought. METHODS: A total of 256 patients with high grade coronary stenosis or occlusion were evaluated for the extent of coronary collaterals using Rentrop classification...
March 9, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28315562/improvement-in-left-ventricular-intrinsic-dyssynchrony-with-cardiac-resynchronization-therapy
#9
Serdar Bozyel, Ayşen Ağaçdiken Ağır, Tayfun Şahin, Umut Çelikyurt, Müjdat Aktaş, Onur Argan, İrem Yılmaz, Kurtuluş Karaüzüm, Emir Derviş, Ahmet Vural, Dilek Ural
OBJECTIVE: Cardiac resynchronization therapy (CRT) has been shown to induce a structural and electrical remodeling; the data on whether left ventricle (LV) reverse remodeling is associated with restitution of intrinsic contraction pattern are unknown. In this study, we investigated the presence of improvement in left ventricular intrinsic dyssynchrony in patients with CRT. METHODS: A total of 45 CRT recipients were prospectively studied. Dyssynchrony indexes including interventricular mechanical delay (IVMD) and tissue Doppler velocity opposing-wall delay (OWD) as well as QRS duration on 12-lead surface electrocardiogram were recorded before CRT device implantation...
March 3, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28315561/polymorphisms-of-lipid-metabolism-enzyme-coding-genes-in-patients-with-diabetic-dyslipidemia
#10
Aslı Tetik Vardarlı, Ece Harman, Vildan Bozok Çetintaş, Meral Kayıkçıoğlu, Egemen Vardarlı, Ayhan Zengi, Ali Şahin Küçükaslan, Zuhal Eroğlu
OBJECTIVE: The polymorphisms/mutations of genes encoding proteins and enzymes involved in lipoprotein metabolism play important roles in the development of diabetic dyslipidemia. The aim of our study was to investigate the effects of LPL (rs320), LIPC (rs2070895), SCARB1 (rs5888), LCAT (rs2292318), CETP (rs708272), ADIPOQ (rs1501299), RETN (rs3745367), PON1 (rs662), and MNSOD (rs4880) gene polymorphisms on lipid metabolism and diabetic dyslipidemia. METHODS: This case-control study included 217 patients with diabetic dyslipidemia and 212 healthy age- and gender-matched individuals...
March 3, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28315566/directly-ventricular-septal-defect-closure-without-using-arteriovenous-wire-loop-our-adult-case-series-using-transarterial-retrograde-approach
#11
Nihat Pekel, Ertuğrul Ercan, Mehmet Emre Özpelit, Ferhat Özyurtlu, Akar Yılmaz, Caner Topaloğlu, Serkan Saygı, Serkan Yakan, İstemihan Tengiz
OBJECTIVE: The standard transcatheter ventricular septal defects (VSD) closure procedure is established with arteriovenous (AV) loop and is called as antegrade approach. The directly retrograde transarterial VSD closure without using AV loop might be better option as shortens the procedure time and decreases radiation exposure. METHODS: Our series consist of twelve sequential adult cases with congenital VSDs (seven with perimembranous, four with muscular, one with postoperative residuel VSD)...
February 21, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28179617/relationship-between-serum-25-hydroxyvitamin-d-levels-and-the-syntax-score-in-patients-with-acute-coronary-syndrome
#12
Ahmet Oğuz Baktır, Yasemin Doğan, Bahadır Şarlı, Ömer Şahin, Erkan Demirci, Mahmut Akpek, Eyüp Özkan, Hüseyin Arınç, Hayrettin Sağlam
OBJECTIVE: The extent of severity and complexity of coronary artery disease (CAD) in patients presenting with ST-segment elevation myocardial infarction (STEMI) and non-STEMI (NSTEMI) and possible correlations between serum 25-hydroxyvitamin D (25(OH)D) have not yet been adequately studied. We evaluated the relationship between 25(OH)D levels and the burden of CAD as assessed by the SYNTAX score (SXscore) in patients with acute coronary syndrome (ACS) including STEMI and NSTEMI. METHODS: After exclusion, a total of 113 patients who were admitted to our hospital due to ACS and who were referred for undergoing coronary angiography were prospectively included...
February 1, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28179616/role-of-simvastatin-and-ror%C3%AE-activity-in-the-macrophage-apoptotic-pathway
#13
Neslihan Çoban, Çağrı Güleç, Bilge Özsait Selçuk, Nihan Erginel-Ünaltuna
OBJECTIVE: Atherosclerosis is a chronic inflammatory condition and is one of the main causes of death worldwide. Macrophages play important roles in the formation of atherosclerotic plaques. Apoptosis is progressively observed while plaques develop, although the precise mechanisms and outcomes of apoptosis in atherosclerosis development and progression are still contradictory. This study was conducted to explore the effects of simvastatin and retinoic acid receptor-related orphan receptor alpha (RORα) ligands on apoptosis in human acute monocytic leukemia (THP-1) macrophage cells...
February 1, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28179615/baseline-serum-globulin-as-a-predictor-of-the-recurrence-of-lone-atrial-fibrillation-after-radiofrequency-catheter-ablation
#14
Qing Zhou, Hailong Cao, Zhenjun Xu, Rongfang Lan, Xin Chen, Dongjin Wang, Wei Xu
OBJECTIVE: Inflammation and autoimmune responses play an important role in recurrence of atrial fibrillation (AF). Serum globulin levels are a commonly used clinical index that represents inflammation and autoimmune response. This study aimed to determine the relationship between baseline serum globulin levels and the risk of recurrence after ablation in lone AF patients. METHODS: We enrolled 348 lone AF patients undergoing radiofrequency catheter ablation for the first time for whom complete follow-up data were available...
February 1, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28179614/genotyping-of-six-clopidogrel-metabolizing-enzyme-polymorphisms-has-a-minor-role-in-the-assessment-of-platelet-reactivity-in-patients-with-acute-coronary-syndrome
#15
María Henar García-Lagunar, Luciano Consuegra-Sánchez, Pablo Conesa-Zamora, Javier Ruiz-Cosano, Federico Soria-Arcos, Luis García de Guadiana, Pedro Cano Vivar, Juan Antonio Castillo-Moreno, Antonio Melgarejo-Moreno
OBJECTIVE: To evaluate the contribution of six polymorphisms to the platelet reactivity in patients with acute coronary syndrome (ACS) treated with clopidogrel. METHODS: Cross-sectional study of 278 consecutive patients with ACS. Detailed clinical information for each patient was collected and genotypes (CYP2C9*2, CYP2C9*3, CYP2C19*2, CYP2C19*17, CYP3A4*1B, and PON1-Q192R) were evaluated with TaqMan® and KASPar® assays. Platelet reactivity was measured with VerifyNow®...
February 1, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28100899/effectiveness-of-computed-tomography-attenuation-values-in-characterization-of-pericardial-effusion
#16
Mehmet Serkan Çetin, Elif Hande Özcan Çetin, Mustafa Özdemir, Serkan Topaloğlu, Dursun Aras, Ahmet Temizhan, Sinan Aydoğdu
OBJECTIVE: The aim of this study was to evaluate the effectiveness of computed tomography (CT) attenuation values in the characterization of pericardial effusion. METHODS: This study consisted of 96 patients with pericardial effusion who underwent pericardiocentesis. For further diagnostic evaluation of pericardial effusion, all the patients were assessed by thorax CT. CT attenuation values were measured from at least 5 different areas of pericardial fluid by specifying the largest region of interest...
January 17, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28100898/new-oral-anticoagulants-turkey-noac-turk-multicenter-cross-sectional-study
#17
Servet Altay, Özlem Yıldırımtürk, Hüseyin Altuğ Çakmak, Lütfü Aşkın, Ümit Yaşar Sinan, Feyzullah Beşli, Ömer Gedikli, Özge Özden Tok
OBJECTIVE: New oral anticoagulants (NOACs) are increasingly used both for prevention of stroke in non-valvular atrial fibrillation (NVAF) and the treatment of venous thromboembolism (VTE). In this study, we aimed to evaluate the current patterns of NOACs treatment in Turkey. Moreover, demographic and clinical parameters and bleeding and/or embolic events under NOACs treatment were analyzed. METHODS: The New Oral Anticoagulants-TURKey (NOAC-TURK) study was designed as a multicenter cross-sectional study...
January 17, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28100897/x-indening-oral-liquid-improves-cardiac-function-of-rats-with-chronic-cardiac-failure-via-tgf-%C3%A3-1-smad3-and-p38-mapk-pathway
#18
Yunliang Wei, Changsheng Guo, Jingsheng Zhao, Jun Yang, Weiguo Yi, Hong Liu, Xinwei Lin, Zhengchen Zhang
OBJECTIVE: Xindening oral liquid (Xin) is a widely used traditional Chinese medicine for the treatment of chronic heart failure (CHF). However, the exact mechanisms related to its therapeutic effects against CHF remain unclear. In the present study, we investigate the effects of Xin on cardiac function in CHF rats and the possible mechanisms involved. METHODS: Transverse aortic constriction (TAC) was conducted to induce a CHF rat model in this study. Sixty male Wistar rats were randomly assigned to six groups 28 days after TAC: sham; CHF model; Xin at concentrations of 5 ml/kg, 10 mL/kg, and 20 mL/kg; and QiLi 0...
January 17, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28100896/investigating-the-effect-of-traditional-persian-music-on-ecg-signals-in-young-women-using-wavelet-transform-and-neural-networks
#19
Behzad Abedi, Ataollah Abbasi, Atefeh Goshvarpour
OBJECTIVE: In the past few decades, several studies have reported the physiological effects of listening to music. The physiological effects of different music types on different people are different. In the present study, we aimed to examine the effects of listening to traditional Persian music on electrocardiogram (ECG) signals in young women. METHODS: Twenty-two healthy females participated in this study. ECG signals were recorded under two conditions: rest and music...
January 17, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28045012/cardiopulmonary-resuscitation-knowledge-among-nursing-students-a-questionnaire-study
#20
Mutlu Vural, Mustafa Feridun Koşar, Orhan Kerimoğlu, Fatih Kızkapan, Serdar Kahyaoğlu, Sevil Tuğrul, Hasan Burak İşleyen
OBJECTIVE: Nurses are usually first witnesses to in-hospital sudden cardiac arrests. Training of nurses has an impact on the efficiency and outcome of cardiopulmonary resuscitation (CPR), and thus, assessment of CPR knowledge among undergraduate nurses is very important to improve training program. METHODS: The questionnaire comprised of three parts about CPR knowledge: the first dealing with general questions to understand the importance of CPR in clinical practice; the second comprising the main goal and accuracy of CPR intervention; and the last consisting of questions targeting the indications, methods, and effectiveness of CPR...
December 28, 2016: Anatolian Journal of Cardiology
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