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Anatolian Journal of Cardiology

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https://www.readbyqxmd.com/read/28639949/comet-assay-in-evaluating-deoxyribonucleic-acid-damage-after-out-of-hospital-cardiac-arrest
#1
Radka Hazuková, Martina Rezácová, Renata Köhlerová, Tomáš Tomek, Eva Cermáková, Jaromír Kocí, Miloslav Pleskot
OBJECTIVE: This study aimed to investigate whether out-of-hospital cardiac arrest (OHCA) may induce severe DNA damage measured using comet assay in successfully resuscitated humans and to evaluate a short-term prognostic role. METHODS: In this prospective, controlled, blinded study (1/2013-1/2014), 41 patients (age, 63±14 years) successfully resuscitated from non traumatic OHCA and 10 healthy controls (age, 53±17 years) were enrolled. DNA damage [double-strand breaks (DSBs) and single-strand breaks (SSBs)] was measured using comet assay in peripheral lymphocytes sampled at admission...
June 22, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28639948/protective-effects-of-il28ra-sirna-on-cardiomyocytes-in-hypoxia-reoxygenation-injury
#2
Ge Gong, Yanyan Li, Xinxing Yang, Hongyu Geng, Xinzheng Lu, Liansheng Wang, Zhijian Yang
OBJECTIVE: We demonstrate the protective effects of the siRNA-mediated inhibition of the interleukin-28 receptor alpha (IL28RA) subunit on cardiomyocytes in hypoxia/reoxygenation (H/R) injury and explore the associated mechanism. METHODS: After designing and synthesizing three pairs of siRNA that effectively reduced IL28RA gene expression in vitro (siRNA-6158, siRNA-6160, and siRNA-6162), primary neonatal rat cardiomyocytes were transfected using a liposome transfection method...
June 22, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28639947/surface-electrocardiogram-could-atrioventricular-nodal-and-his-bundle-potentials-be-recorded-beat-by-beat-on-saah-electrocardiogram
#3
Qinghua Chang, Renguang Liu, Juan Chen
OBJECTIVE: The P-QRS-T wave on surface electrocardiogram (ECG) reflects the changes in atrial and ventricular electrical properties. However, the atrioventricular conduction system potentials cannot be recorded to date. This study aimed to explore the possibility of micropotential of the atrioventricular conduction system recorded by surface "SAN-Atrial-AVN-His (Saah) ECG." METHODS: We randomized 100 healthy volunteers (50 females and 50 males; mean age 25.12±1...
June 22, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28639946/assessment-of-left-ventricular-systolic-function-in-patients-with-iron-deficiency-anemia-by-three-dimensional-speckle-tracking-echocardiography
#4
Qiao Zhou, Jiaqi Shen, Yue Liu, Runlan Luo, Bijun Tan, Guangsen Li
OBJECTIVE: The present study aimed to evaluate left ventricular (LV) systolic function in patients with iron deficiency anemia (IDA) by 3 dimensional speckle-tracking echocardiography (3DSTE). METHODS: Participants were grouped by hemoglobin (Hb) levels in order to study the effect of anemia on cardiac function. Group A included 40 healthy volunteers. Eighty-three patients who were diagnosed with IDA were divided into 2 groups according to the Hb level. Group B (Hb 9 g/dL) included 44 patients, while group C (Hb 6-9 g/dL) included 39 patients...
June 22, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28639945/pulmonary-arterial-hemodynamic-assessment-by-a-novel-index-in-systemic-lupus-erythematosus-patients-pulmonary-pulse-transit-time
#5
Tolga Han Efe, Mehmet Doğan, Cem Özişler, Tolga Çimen, Mehmet Ali Felekoğlu, Ahmet Göktuğ Ertem, Engin Algül, Sadık Açıkel
OBJECTIVE: Systemic lupus erythematosus (SLE) is a chronic, inflammatory, and autoimmune connective tissue disease. One of the leading causes of mortality among SLE patients is pulmonary hypertension. The aim of this study was to evaluate the association between echocardiographic findings, including the pulmonary pulse transit time and pulmonary hypertension parameters, in SLE patients. METHODS: Thirty SLE patients (aged 39.9±11 years, 28 females) as the study group and 34 age- and sex-matched healthy volunteers (aged 37...
June 22, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28639944/clinical-impact-and-efficacy-of-bedside-echocardiography-on-patient-management-in-pediatric-intensive-care-units-picus-a-prospective-study
#6
Sanliay Şahin, Mutlu Uysal Yazıcı, Ganime Ayar, Tülin Köksal, İbrahim İlker Çetin, Filiz Ekici, Abdullah Kocabaş
OBJECTIVE: To determine the indication and necessity of echocardiographic assessment and therapeutic interventions in critically ill children. METHODS: A total of 140 children, including 75 mechanically ventilated (MV) and 65 spontaneously breathing (SB) children, who were admitted consecutively from March to August 2013 were evaluated prospectively. Data regarding the indication for echocardiography and therapeutic approaches used were documented. For evaluating disease severity, the Pediatric Risk of Mortality Score III (PRISM) was ascertained...
June 22, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28559533/assessment-of-the-association-between-the-presence-of-fragmented-qrs-and-the-predicted-risk-score-of-sudden-cardiac-death-at-5-years-in-patients-with-hypertrophic-cardiomyopathy
#7
Sinem Özyılmaz, Özgür Akgül, Hüseyin Uyarel, Hamdi Pusuroğlu, Muammer Karayakalı, Mehmet Gül, Mustafa Çetin, Hulusi Satılmışoğlu, Aydın Yıldırım, İhsan Bakır
OBJECTIVE: It has been shown that the presence of fragmented QRS (fQRS) is associated with poor prognosis in many cardiovascular diseases and in patients with hypertrophic cardiomyopathy (HCM). However, no study has shown an association with the absolute risk score of sudden cardiac death. The aim of this study was to determine the relationship between QRS and the predicted risk score of sudden cardiac death at 5 years (HCM Risk-SCD) in HCM patients. METHODS: In total, 115 consecutive HCM patients were included in this prospective observational study...
May 30, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28559532/-desert-gene-chr9p21-variants-as-novel-markers-for-coronary-artery-disease
#8
Heba A Shendy, Sally I Hassanein, Mohamed Z Gad
OBJECTIVE: Previous reports have denoted to the possible link of Chr9p21 locus to the incidence of coronary artery disease (CAD). The entire core of chr9p21 is covered by "ANRIL" (Antisense noncoding RNA in INK4 Locus) and lies in a region that is free from any coding proteins; therefore, it is called the desert gene. The major objectives of this study were to examine the association of rs10757278 and rs2383206 SNPs on Chr9p21 with the incidence of CAD in the presence and absence of type 2 diabetes (T2D) in Egyptians and to correlate these genetic variants with several disease biomarkers (TC, CRP, and HbA1c)...
May 30, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28559531/association-between-left-atrial-function-assessed-by-speckle-tracking-echocardiography-and-the-presence-of-left-atrial-appendage-thrombus-in-patients-with-atrial-fibrillation
#9
Karolina Kupczynska, Blazej W Michalski, Dawid Miskowiec, Jaroslaw D Kasprzak, Paulina Wejner-Mik, Katarzyna Wdowiak-Okrojek, Piotr Lipiec
OBJECTIVE: The aim of the study was to investigate whether the deformation of left atrium (LA) measured by speckle-tracking analysis (STE) is associated with the presence of LA appendage thrombus (LAAT) during non-valvular atrial fibrillation (AF). METHODS: Eighty-seven patients (mean age 67 years, 59% men) were included to retrospective cross-sectional study. On top of standard echocardiography we assessed: LA longitudinal systolic strain (LS), systolic (LSSR) and early diastolic strain rate (LESR) in four-chamber and twochamber apical views...
May 30, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28554990/the-role-of-scube1-in-the-pathogenesis-of-no-reflow-phenomenon-presenting-with-st-segment-elevation-myocardial-infarction
#10
Hasan Ata Bolayır, Hakan Güneş, Tarık Kıvrak, Ömer Şahin, Dursun Akaslan, Recep Kurt, Aslı Bolayır, Oya İmadoğlu
OBJECTIVE: SCUBE1 [signal peptide-CUB (complement C1r/C1 s)-EGF (epidermal growth factor)-like domain-containing protein 1] might function as a novel platelet-endothelial adhesion molecule and play pathological roles in cardiovascular biology. Acute myocardial infarction is one of the most common causes of death in modern society. The concept of "no reflow" (NR) refers to a state of myocardial tissue hypoperfusion in the presence of a patent epicardial coronary artery. The main mechanisms of this phenomenon are thought to be high platelet activity and much thrombus burden...
May 24, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28554989/previous-cerebrovascular-disease-is-an-important-predictor-of-clinical-outcomes-in-elderly-patients-with-percutaneous-coronary-interventions-the-nobori-biolimus-eluting-stent-prospective-multicenter-1-year-observational-registry-in-south-korea
#11
Yong Hoon Kim, Ae Young Her, Byeong Keuk Kim, Dong Ho Shin, Jung Sun Kim, Young Guk Ko, Donghoon Choi, Myeong Ki Hong, Yangsoo Jang
OBJECTIVE: The appropriate selection of elderly patients for revascularization has become increasingly important because these subsets of patients are more likely to experience a major cardiac or cerebrovascular event-percutaneous coronary intervention (PCI). The objective of this study was to determine important independent risk factor for predicting clinical outcomes in the elderly patients after successful PCI, particularly in a series of South Korean population. METHODS: This study is prospective, multicenter, observational cross-sectional study...
May 24, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28554988/effects-of-garlic-on-brachial-endothelial-function-and-capacity-of-plasma-to-mediate-cholesterol-efflux-in-patients-with-coronary-artery-disease
#12
Marjan Mahdavi-Roshan, Parvin Mirmiran, Mohammad Arjmand, Javad Nasrollahzadeh
OBJECTIVE: This study investigated the effects of garlic on brachial endothelial function and THP-1 macrophage cholesterol efflux (CE) and examined whether garlic modulates ATP-binding cassette (ABC) A1 and ABCG1 mRNA expressions in peripheral blood mononuclear cells (PBMCs) isolated from patients with coronary artery disease (CAD). METHODS: In this randomized, placebo-controlled trial, patients with CAD were randomly divided into two groups: those receiving garlic powder or placebo tablets twice daily for 3 months...
May 24, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28554987/the-impact-of-cardiac-rhythm-on-the-mitral-valve-area-and-gradient-in-patients-with-mitral-stenosis
#13
Hasan Arı, Selma Arı, Alper Karakuş, Sencer Camcı, Kübra Doğanay, Ahmet Tütüncü, Mehmet Melek, Tahsin Bozat
OBJECTIVE: The aim of this study was to evaluate the effect of cardiac rhythm on the echocardiographic mitral valve area (MVA) and transmitral gradient calculation in relation to net atrioventricular compliance (Cn). METHODS: Patients (n=22) with mild or moderate pure rheumatic mitral stenosis (MS) (MVA <2 cm2 and MVA >1 cm2) and atrial fibrillation (AF) were evaluated. All patients underwent transthoracic electrical DC cardioversion under amiodarone treatment...
May 24, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28554986/connexin-43-is-involved-in-the-sympathetic-atrial-fibrillation-in-canine-and-canine-atrial-myocytes
#14
Chenglin Shu, Weiqiang Huang, Zhiyu Zeng, Yan He, Beibei Luo, Hao Liu, Jinyi Li, Jian Xu
OBJECTIVE: Atrial fibrillation (AF) is the most common rapid cardiac arrhythmia associated with high morbidity and mortality. Stimulation of the sympathetic nerve is involved in AF occurrence. The gap junction protein connexin 43 (Cx43) plays a key role in electrical conduction velocity in cardiac tissues, and under expression of Cx43 was linked with AF. The aim of this study was to investigate whether Cx43 was involved in sympathetic AF. METHODS: Fifteen dogs were randomly divided into 3 groups (5 in each group)...
May 24, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28554985/evaluation-of-the-ambulatory-arterial-stiffness-index-in-lead-exposed-workers
#15
Uğur Nadir Karakulak, Ömer Hınç Yılmaz, Engin Tutkun, İhsan Ateş, Ceylan Bal, Meside Gündüzöz
OBJECTIVE: Lead exposure has been associated with various cardiovascular disorders. It may also cause increased inflammation and fibrosis in the arterial system resulting in an increase in arterial stiffness. In this study, the ambulatory arterial stiffness index (AASI), which is a technique that measures arterial stiffness, was evaluated in occupationally lead-exposed workers. METHODS: In this cross-sectional study, 68 lead-exposed workers without known cardiovascular risk factors and 68 healthy subjects were evaluated according to the 24-hour ambulatory blood pressure monitorization (ABPM) profiles and blood and 24-hour urine lead levels...
May 24, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28529297/statins-in-paroxysmal-atrial-fibrillation-beneficial-to-prevent-recurrence-but-insufficient-to-stop-progression-to-prevent-recurrence-but-insufficient-to-stop-progression
#16
EDITORIAL
https://www.readbyqxmd.com/read/28529296/radiationless-transseptal-puncture
#17
EDITORIAL
Jakub P Holda
No abstract text is available yet for this article.
May 9, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28529295/directly-ventricular-septal-defect-closure-without-using-arteriovenous-wire-loop-our-adult-case-series-using-transarterial-retrograde-approach
#18
EDITORIAL
Sedigheh Saedi, Tahereh Saedi
No abstract text is available yet for this article.
May 9, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28529294/left-ventricular-twist-in-patients-with-left-bundle-branch-block-missing-the-obvious-in-electromechanical-coupling
#19
EDITORIAL
Alaa Mabrouk Salem Omar, Piedad Lerena Saenz
No abstract text is available yet for this article.
May 9, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28430114/urban-and-rural-differences-in-hypertension-risk-factors-in-turkey
#20
İlker Daştan, Ayşegül Erem, Volkan Çetinkaya
OBJECTIVE: Existing literature shows considerable regional differences in terms of hypertension (HT) prevalence in Turkey. The purpose of this study was to analyze some of the known HT risk factors contributing to the variations between urban and rural areas of Turkey in HT development. METHODS: We used data from the 2011 Chronic Diseases and Risk Factors Survey that was conducted by the Turkish Ministry of Health on a representative sample of the Turkish adult population aged 20 years or more (n=16...
April 19, 2017: Anatolian Journal of Cardiology
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