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Gynecologic Oncology Reports

Stephanie H Smith, Sri Krishna C Arudra, Mary M Mullen, Marguerite Palisoul, Sonika Dahiya, P Kumar Rao, Premal H Thaker
•Choroid metastases are extremely rare in endometrial cancer.•Choroid metastases can present as many different eye complaints.•Comprehensive eye exams are important in patients with visual complaints.
February 2018: Gynecologic Oncology Reports
Michiko Kaiho-Sakuma, Masafumi Toyoshima, Mika Watanabe, Asami Toki, Satomi Kameda, Takamichi Minato, Hitoshi Niikura, Nobuo Yaegashi
•Neuroendocrine tumors (NETs) frequently occur in the lungs or the gastrointestinal tract; they are uncommon in the ovary.•The mammalian target of rapamycin (mTOR) pathway has been reported as a treatment for advanced NETs.•We describe a patient with an aggressive primary ovarian NET, successfully treated with everolimus (an mTOR inhibitor).
February 2018: Gynecologic Oncology Reports
Mary G Dandulakis, Aidas J Mattis, Andrea R Hagemann, Ian S Hagemann
•A histologically low-grade cervical clear cell lesion was observed.•Proliferating cells were seen only at the periphery of this lesion.•Due to its low proliferation index, this may represent a precursor of clear cell carcinoma.•Further definition of such lesions may allow for more minimal management.
February 2018: Gynecologic Oncology Reports
John P Micha, Dung H Nguyen, Bram H Goldstein
Introduction: Lower-extremity lymphedema is a significant complication attributed to gynecologic cancer surgery, potentially effectuating severe edema and discernible pain. Case report: We report on a patient who developed persistent, lower-extremity lymphedema following her treatment for cervix cancer. Despite repeated efforts to manage the lymphedema with conventional measures, the patient's condition had not markedly improved. Thereafter, she underwent a suction-assisted lipectomy that effectively resolved her symptoms...
February 2018: Gynecologic Oncology Reports
Amishi Bajaj, Mahesh Gopalakrishnan, Matthew M Harkenrider, John R Lurain, William Small
The purpose of this article is to present a case of successful treatment of a patient with stage IVB small cell carcinoma of the cervix (SCCC) who was treated with concurrent chemoradiotherapy (CCRT) consisting of etoposide/cisplatin (EP) chemotherapy, external beam radiation therapy (EBRT), and brachytherapy. The patient has since remained without evidence of disease for nearly six years. This report reviews and summarizes the existing case literature on SCCC.
February 2018: Gynecologic Oncology Reports
Carlie Field, Barbara A Goff
•Young women with dermatomyositis are at high risk for underlying ovarian cancer.•Dermatomyositis symptoms can be used to assess treatment and recurrence of disease.•Immunosuppression can complicate postoperative recovery in ovarian cancer patients.•Ovarian cancer patients with dermatomyositis should have genetic testing.
February 2018: Gynecologic Oncology Reports
Madhuri Martin, Rachel N Grisham, Gulisa Turashvili, Darragh F Halpenny, Carol A Aghajanian, Vicky Makker
[This corrects the article DOI: 10.1016/j.gore.2017.09.001.].
November 2017: Gynecologic Oncology Reports
Humera Mahmood, Hadia Fatima, Mohammad Faheem
[This corrects the article DOI: 10.1016/j.gore.2017.05.007.].
November 2017: Gynecologic Oncology Reports
Diane M Harper, Leslie R DeMars
No abstract text is available yet for this article.
November 2017: Gynecologic Oncology Reports
Lois Ramondetta
No abstract text is available yet for this article.
November 2017: Gynecologic Oncology Reports
David Cibula
No abstract text is available yet for this article.
November 2017: Gynecologic Oncology Reports
Michael Höckel
No abstract text is available yet for this article.
November 2017: Gynecologic Oncology Reports
William T Jaegle, Jason C Barnett, Bridget R Stralka, Nicole P Chappell
Background: Tamoxifen is a medication often used for the treatment and prevention of breast cancer. It is classically associated with several gynecological side effects to include a thickened endometrial stripe, increased uterine polyp formation, and an increased risk of uterine cancer. Rarely tamoxifen use has been associated with proliferation of endometriosis often severe enough to mimic a late-stage gynecologic malignancy. Case: A 62-year-old Gravida 0 postmenopausal female with a medical history of severe obesity, infertility, and preventative tamoxifen use presented for evaluation of gross hematuria...
November 2017: Gynecologic Oncology Reports
Abigail S Zamorano, Leping Wan, Matthew A Powell, L Stewart Massad
Our objective was to assess overall survival of cervical cancer patients following prior platinum/bevacizumab chemotherapy, comparing retreatment with platinum/bevacizumab with alternative therapies. A retrospective analysis was performed of women who received platinum/bevacizumab (PB) chemotherapy for cervical cancer at Washington University between July 1, 2005 and December 31, 2015. Wilcoxon rank-sum exact test and Fisher's exact test were used to compare the treatment groups, and Kaplan Meier curves were generated...
November 2017: Gynecologic Oncology Reports
Neil A J Ryan, James Bolton, Rhona J McVey, D Gareth Evans, Emma J Crosbie
No abstract text is available yet for this article.
November 2017: Gynecologic Oncology Reports
Reshma Muppala, Talia Donenberg, Marilyn S Huang, Matthew P Schlumbrecht
Background: SMARCA4 is gene whose protein product participates in chromatin remodeling. Somatic mutations in this gene are associated with non-small cell lung cancer and malignant rhabdoid tumors, and both germline and somatic mutations are seen with small cell carcinoma of the ovary, hypercalcemic type. To date, there are no data identifying an association with more common epithelial carcinomas of the ovary. Case: The patient is a 57-year-old female without any significant family history of cancer, diagnosed with high-grade serous carcinoma of the ovary...
November 2017: Gynecologic Oncology Reports
Patrícia Taranto, Filomena M Carvalho, Sergio Roithmann, Fernando C Maluf
Yolk sac tumor (YST) is the second most common subtype of ovarian germ cell tumors. It usually occurs in the second and third decades of life and is rare in postmenopausal women. In postmenopausal women, YST is commonly an aggressive tumor and can present as a pure germ cell component or as a mixed component with other germ cell or epithelial components. The recognition of this histological subtype is important not only for differential diagnosis but also for determining prognosis and treatment decisions. In this case report, we describe a 61-year-old woman with YST coexisting with epithelial carcinoma focusing on the efficacy of systemic therapies...
November 2017: Gynecologic Oncology Reports
Stephanie Ricci, Ana I Tergas, Kara Long Roche, Melissa Gerardi Fairbairn, Kimberly L Levinson, Sean C Dowdy, Robert E Bristow, Micael Lopez, Katrina Slaughter, Kathleen Moore, Amanda N Fader
A recent ASCO workforce study projects a significant shortage of oncologists in the U.S. by 2020, especially in rural/underserved (R/US) areas. The current study aim was to determine the patterns of distribution of U.S. gynecologic oncologists (GO) and to identify provider-based attitudes and barriers that may prevent GOs from practicing in R/US regions. U.S. GOs (n = 743) were electronically solicited to participate in an on-line survey regarding geographic distribution and participation in outreach care...
November 2017: Gynecologic Oncology Reports
Diana C Pearre, Jerome J Federspiel, Francis C Grumbine
•Solitary fibrous tumors are typically indolent tumors of the pleura.•Primary origin in the female reproductive organs is rare, as are aggressive forms.•We report a case of a vulvar solitary fibrous tumor, notable for extensive spinal metastasis.
November 2017: Gynecologic Oncology Reports
Ram Eitan, Daliah Tsoref, Gad Sabah, Lina Salman
•Extra-peritoneal metastasis is uncommon in epithelial ovarian carcinoma.•Metastasis of epithelial ovarian carcinoma to axillary lymph node is rare.•Lymphatic drainage system can explain the rout of this distant metastasis.•Tissue diagnosis is the mainstay in identifying the origin of axillary metastasis.
November 2017: Gynecologic Oncology Reports
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