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Gynecologic Oncology Reports

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https://www.readbyqxmd.com/read/28861460/incidental-fallopian-tube-mesothelioma-diagnosed-at-time-of-elective-bilateral-salpingectomy-for-sterilisation-a-case-report
#1
J Phillips-Yelland, D Payton, R Land, A Kaur
•Incidental finding of a fallopian tube lesion at the time of bilateral salpingectomy•Histopathological appearance not consistent with mucinous or serous carcinoma, appearance of mesothelioma•Very rare known primary neoplasm of tubal mesothelium, favours an indolent course•Recommendation for prophylactic hysterectomy and bilateral oophorectomy•If nil further spread, generally nil further treatment is required.
November 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28861459/development-of-a-comprehensive-and-sustainable-gynecologic-oncology-training-program-in-western-kenya-a-low-resource-setting
#2
Barry Rosen, Peter Itsura, Philip Tonui, Alan Covens, Luc van Lonkhuijzen, Elkanah Omenge Orang'o
To provide information on the development of a gynecologic oncology training program in a low-resource setting in Kenya. This is a review of a collaboration between Kenyan and North American physicians who worked together to develop a gynecologic oncology training in Kenya. We review the published data on the increase of cancer incidence in sub-Saharan Africa and outline the steps that were taken to develop this program. The incidence of cervical cancer in Kenya is very high and is the leading cause of cancer mortality in Kenya...
August 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28831418/primary-low-grade-endometrial-stromal-sarcoma-of-the-omentum
#3
Kiran Clair, Juliet Wolford, Sonia Veran-Taguibao, Grace Kim, Ramez N Eskander
•Extra-uterine endometrial stromal sarcoma may arise in endometriosis.•Abdominal exploration for extra pelvic endometriosis is warranted.•Representative endometriotic implants should be resected and/or biopsied if clinically suspicious.
August 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28831417/dual-progestin-therapy-for-fertility-sparing-treatment-of-grade-2-endometrial-adenocarcinoma
#4
A M Newtson, J B Pakish, A M Nick, S N Westin
•A case of grade 2 endometrial adenocarcinoma in a young woman desiring fertility-sparing treatment•Successful conservative management of refractory endometrial adenocarcinoma with dual progestin therapy•A brief review of conservative management in endometrial adenocarcinoma.
August 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28831416/the-use-of-quikclot-combat-gauze-in-cervical-and-vaginal-hemorrhage
#5
Nicole Vilardo, Jacqueline Feinberg, Jonathan Black, Elena Ratner
QuikClot combat gauze is a synthetic hemostatic dressing used for hemorrhage control. There is a paucity of data describing the clinical use and hemostatic results of combat gauze in the obstetric and gynecologic setting. This case series demonstrates the use of combat gauze as an effective hemostatic agent when used as vaginal packing in cervical and vaginal hemorrhage. Hemostasis was achieved rapidly in all cases and further interventions were avoided. The combat gauze remained in place for a mean time of 15 h with no adverse side effects observed...
August 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28819635/strengthening-care-and-research-for-women-s-cancers-in-sub-saharan-africa
#6
REVIEW
Thomas C Randall, Linus Chuang, ElkanahOmenge Orang'o, Barry Rosen, Francois Uwinkindi, Timothy Rebbeck, Edward L Trimble
•The burden of gynecologic cancers in low resource settings is overwhelming.•Areas with the highest needs have few human resources and limited infrastructure.•Cancer specialists can best help by leveraging ongoing work to assist local leaders.
August 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28819634/cervical-cancer-control-in-hiv-infected-women-past-present-and-future
#7
REVIEW
Rahel G Ghebre, Surbhi Grover, Melody J Xu, Linus T Chuang, Hannah Simonds
Since the initial recognition of acquired immunodeficiency syndrome (AIDS) in 1981, an increased burden of cervical cancer was identified among human immunodeficiency virus (HIV)-positive women. Introduction of antiretroviral therapy (ART) decreased risks of opportunistic infections and improved overall survival. HIV-infected women are living longer. Introduction of the human papillomavirus (HPV) vaccine, cervical cancer screening and early diagnosis provide opportunities to reduce cervical cancer associated mortality...
August 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28795132/spontaneous-regression-of-gestational-trophoblastic-neoplasia
#8
Kaoru Niimi, Eiko Yamamoto, Kimihiro Nishino, Sawako Fujiwara, Kazuhiko Ino, Fumitaka Kikkawa
•We present two cases of postmolar gestational trophoblastic neoplasia (GTN).•Both cases presented with lung metastases after hydatidiform mole.•Both cases showed spontaneous regression without treatment.•The mechanism behind this phenomenon remains unclear.•Patients with postmolar GTN and declining hCG values may not need chemotherapy.
August 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28795131/primary-pouch-of-douglas-malignancies-a-case-series-and-review-of-the-literature
#9
Ker Yi Wong, Ada Xinhui Ng, Timothy Yong Kuei Lim
•POD lesions are often diagnosed as ovarian or uterine in origin on imaging.•POD malignancies with concomitant endometriosis, appear to be of lower grade.•There is no consensus on the optimal treatment for rare primary POD neoplasms.
August 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28795130/epithelioid-angiosarcoma-of-the-vulva-a-case-report
#10
S Yost, J Bradish, L Grossheim, A Hoekstra
•Vulvar angiosarcoma in a patient with pelvic radiation and chronic lymphedema•Epithelioid histologic staining positive for vimentin, ERG, CD31•Gross appearance of violaceous hyperpigmentation of the mons pubis.
August 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28795129/placental-site-trophoblastic-tumor-with-sole-metastasis-to-breast-a-case-report
#11
Kimberly Nagamine, Sophia Iwasaki, David Shimizu, Pamela Tauchi-Nishi, Keith Terada
Placental site trophoblastic tumor (PSTT) is a rare form of gestational trophoblastic neoplasia (GTN). It most commonly occurs after a delivery but may arise after any type of pregnancy. PSTT arises after neoplastic transformation of intermediate trophoblastic cells. The most commonly reported symptoms are abnormal bleeding or amenorrhea. Due to the rarity of this disease, evidence on prognostic factors as well as optimal treatment is limited. While treatment for early-stage disease is usually limited to surgery, multimodal treatment with chemotherapy and surgery may be important for metastatic disease...
August 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28761925/recurrent-atypical-polypoid-adenomyoma-and-pregnancy-a-new-conservative-approach-with-levonorgestrel-releasing-intrauterine-system
#12
Eugenio Solima, Valeria Liprandi, Gaia M Belloni, Michele Vignali, Mauro Busacca
•Levonorgestrel IUD was effective in treatment of recurrent APA.•No side effects were reported.•No impairments on a subsequent pregnancy were reported.
August 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28761924/secondary-uterine-carcinosarcoma-after-concurrent-chemoradiotherapy-for-cervical-cancer-case-reports
#13
Akihiko Wakayama, Wataru Kudaka, Tadaharu Nakasone, Yusuke Taira, Yoichi Aoki
•Secondary uterine sarcomas occur in < 1% of patients treated with CCRT.•Secondary uterine sarcomas can occur > 5 years from CCRT.•The median survival period from the secondary tumor occurrence was only 4 months.•All our patients had heterologous carcinosarcoma of the uterine corpus.
August 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28736741/elevated-tumor-mutational-burden-and-prolonged-clinical-response-to-anti-pd-l1-antibody-in-platinum-resistant-recurrent-ovarian-cancer
#14
Christopher B Morse, Julia A Elvin, Laurie M Gay, John B Liao
•We report an ovarian cancer patient with a prolonged response to immunotherapy.•Comprehensive genomic profiling may detect patients who benefit from immunotherapy.•Mutational burden thresholds for ovarian cancer may be lower than other cancers.
August 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28725677/a-population-based-study-of-cervical-cytology-findings-and-human-papillomavirus-infection-in-a-suburban-area-of-thailand
#15
Natacha Phoolcharoen, Nuttavut Kantathavorn, Thaniya Sricharunrat, Siriporn Saeloo, Waraphorn Krongthong
Despite the high incidence of cervical cancer in Thailand, large population-based studies on cervical cytology and HPV prevalence and genotype distribution are rare. This study aimed to determine cervical cytology results and the prevalence and distribution of HPV among Thai females in Bangkhayaeng subdistrict, Pathumthani province, Thailand. Of 4681 female inhabitants, aged 20-70 years, 1523 women finally participated in the study. Cervical samples using liquid-based cytology were collected during February-August 2013 and analyzed for HPV genotype by the LINEAR ARRAY® HPV Genotyping Test (Roche, USA)...
August 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28725676/challenges-to-cervical-cancer-treatment-in-bangladesh-the-development-of-a-women-s-cancer-ward-at-dhaka-medical-college-hospital
#16
REVIEW
N Haque, A F M K Uddin, B R Dey, F Islam, A Goodman
Cervical cancer is the second most common cause of female cancer mortality worldwide. Concurrent chemoradiotherapy represents the standard of care for patients with stages IB2 to IVa cervical cancer. Unfortunately radiation therapy capacity is severely limited to non-existent in many Low and Middle-Income Countries. One solution has been to use chemotherapy to reduce tumor size to allow for radical surgery or in the case of inoperable cancers, as a placeholder until radiation is available. In Bangladesh, there has been the progressive development of resources for the treatment of women with gynecologic cancers...
August 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28706968/brca1-reversion-mutation-acquired-after-treatment-identified-by-liquid-biopsy
#17
Paul Mayor, Laurie M Gay, Shashikant Lele, Julia A Elvin
•Secondary, reversion mutations in BRCA genes can restore protein function.•Reversion mutations can underlie resistance to therapies such as PARP inhibitors.•Reversion mutations arise during the course of treatment.
August 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28702501/patterns-of-cervical-cancer-care-in-argentina-applying-asco-recommendations-adjusted-by-local-resources
#18
REVIEW
Agustín Apás Pérez De Nucci, Lucas Minig, Myriam Perrotta
There are significant differences in cervical cancer incidence and mortality between low-middle and high-income countries. The American Society of Clinical Oncology (ASCO) resource-stratified clinical practice guideline was designed to provide an appropriate cervical cancer treatment based on the best available evidence in scenarios with different diagnostic and therapeutic resources. Argentina, a Latin American high middle income country, shows however, that cervical cancer rates are similar to those of low-income countries...
August 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28702500/surgical-management-of-a-large-neurilemmoma-like-leiomyoma-of-the-uterine-cervix-mimicking-a-retroperitoneal-tumor
#19
David A Morales F, Oscar Suescún, Laura Martínez, Isabel Dulcey
•A large cervical neurilemmoma-like leiomyoma can simulate a retroperitoneal tumor.•They are extremely rare tumors that require adequate bleeding control.•Comprehensive anatomo-pathological study should be done to rule out malignancy.
August 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28702499/metastasis-of-cervical-cancer-to-breast-a-case-report-and-review-of-literature
#20
Ankit Mangla, Nikki Agarwal, Farid Saei Hamedani, Jiaxiang Liu, Shweta Gupta, Michael R Mullane
Metastasis to the breast from an extra-mammary malignancy has been documented in literature, however cervical cancer metastasis to the breast is very rare. Thirty-eight cases of metastatic deposit to the breast from cervical cancer have been reported in literature. Though most patients present with a breast lump, it is very difficult to clinically distinguish a primary breast malignancy from a metastatic deposit. Histopathology of the tissue, aided with immune-histochemical staining pattern provides a definitive diagnosis...
August 2017: Gynecologic Oncology Reports
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