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Gynecologic Oncology Reports

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https://www.readbyqxmd.com/read/28331901/isolated-port-site-recurrence-of-node-negative-clinical-stage-ib1-cervical-adenocarcinoma
#1
Uma Deshmukh, Molly McAdow, Jonathan Black, Pei Hui, Masoud Azodi
INTRODUCTION: Port site metastasis after laparoscopic surgery for cervical cancer is a rare phenomenon. METHODS: We present a case report of isolated port site recurrence 4 years following laparoscopic surgery in a patient with node-negative, clinical stage IB1 cervical adenocarcinoma. RESULTS: A 44 year-old woman presented with a necrotic cervical lesion. A biopsy of the mass revealed invasive endocervical adenocarcinoma. She underwent a robotic-assisted radical hysterectomy, bilateral salpingectomy, and pelvic lymph node dissection with bilateral oophoropexy...
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28331900/a-recurrent-endometrial-stromal-sarcoma-harbors-the-novel-fusion-jazf1-bcorl1
#2
Allison J Allen, Siraj M Ali, Kyle Gowen, Julia A Elvin, Tanja Pejovic
•Genomic alterations may improve diagnostic certainty and subsequent treatment of endometrial stromal sarcoma.•Novel JAZF1-BCORL1 mutation was identified.•Targeted therapeutics to down-stream targets may improve survival benefit in these patients.
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28317007/the-role-of-neoadjuvant-chemotherapy-in-the-management-of-patients-with-advanced-stage-ovarian-cancer-survey-results-from-members-of-the-society-of-gynecologic-oncologists-a-5-year-follow-up
#3
Erica Huelsmann, Israel Zighelboim, Amina Ahmed, Summer Dewdney
•NACT use among SGO members for ovarian cancer is explored given recent trials.•Fewer SGO members feel they can't predict optimal cytoreduction pre-operatively.•Laparoscopy use has increased both for diagnosis and treatment of ovarian cancer.•Very high optimal cytoreduction rates are reported from SGO members.•Despite recent studies, SGO members don't regularly treat patients with NACT/ID.
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28275696/surgical-management-of-squamous-cell-vulvar-cancer-without-clitoris-urethra-or-anus-involvement
#4
REVIEW
Alpaslan Kaban, Işık Kaban, Selim Afşar
Vulvar cancers, which constitute 5% of all gynecologic cancers, are the fourth most common female genital cancers, preceded by uterine, ovarian and cervical cancers. The treatment methods employed for vulvar cancers have changed over the years, with previously applied radical surgical approaches, such as en bloc resection, being gradually suspended in favor of treatment approaches that require dissection of less tissue. While the removal of less tissue, which today's approaches have focused on, prevents morbidity, this method seems to result in higher risks of recurrence...
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28275695/cervical-cancer-screening-and-treatment-in-uganda
#5
REVIEW
Carolyn Nakisige, Melissa Schwartz, Anthony Okoth Ndira
Cervical cancer is the leading cause of cancer death among women in Uganda. Given the high prevalence of genital human papillomavirus infection, the current unavailability of radiotherapy, and the absence of a national cervical cancer prevention and control program, these deaths will likely increase. Efforts to organize an effective cervical cancer screening and treatment program will require adequate financial resources, the development of infrastructure, training needed manpower, and surveillance mechanisms of the targeted women...
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28275694/clear-cell-adenocarcinoma-of-the-cervix-in-second-generation-young-women-who-are-without-maternal-exposure-to-diethylstilbestrol-a-case-report
#6
Tanitra Tantitamit, Suttha Hamontri, Likit Rangsiratanakul
Clear cell adenocarcinoma of the cervix (CCAC) is a rare type of gynecological cancer. The risk factors and pathogenesis have yet to be clearly determined. This is a case report of a 19-year-old woman, who was never exposed to DES from her mother, who had gone for an examination for vaginal bleeding. A polypoid mass measured at 3 cm presenting in her cervix was discovered. Histological diagnosis following cervical biopsy proved the tumor to be a clear cell carcinoma. The patient was then referred to our hospital...
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28271093/uterine-sarcoma-with-ambiguous-histomorphology-a-case-report
#7
Eirwen M Miller, Yumei Fu, Ruben Barrera Vera, Gary L Goldberg, Rouzan G Karabakhtsian
BACKGROUND: Leiomyosarcomas (LMS) and endometrial stromal sarcomas (ESS) may display overlapping histomorphology, which may challenge diagnostic accuracy. Since LMS and ESS have vastly different clinical behavior and adjuvant therapy recommendations, accurate diagnosis is critical. CASE: We present the case of an 83-year-old female with postmenopausal bleeding who underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy for clinically atypical appearing leiomyomata...
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28243626/metastases-from-lung-adenocarcinoma-within-a-leiomyoma-a-case-report
#8
Shannon K Rush, Mirna N Toukatly, Mark R Kilgore, Renata R Urban
BACKGROUND: Pulmonary adenocarcinoma rarely spreads to the gynecologic tract, and has not been fully reported to metastasize within a leiomyoma. CASE: A 47 year-old woman with recurrent pulmonary adenocarcinoma was incidentally found to have a positron emission tomography (PET) avid pelvic mass at the time of restaging. She was also noted to be anemic, and reported significant vaginal bleeding. She was taken for an uncomplicated hysterectomy. She was unexpectedly found to have adenocarcinoma within a leiomyoma, consistent with metastasis from her primary pulmonary adenocarcinoma...
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28224136/challenges-to-development-of-cervical-and-breast-cancer-program-development-in-post-conflict-liberia-presentation-prepared-for-african-first-ladies-conference-10th-scca-conference-addis-ababa-ethiopia-2016
#9
Ann Marie Beddoe
•Integrating cancer care in post-conflict settings.•Building health worker and infrastructure for cancer care in low resource setting.•Foreword by Her Excellency President Sirleaf, Republic of Liberia.
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28224135/aortic-utero-ovarian-sentinel-nodes-and-left-infrarenal-aortic-lymph-node-dissection-by-icg-supported-navigation
#10
Rainer Kimmig, Peter Rusch, Paul Buderath, Bahriye Aktas
•Visualization of paraaortic sentinel compartments in endometrial cancer•Nerve sparing dissection of left paraaortic infrarenal lymph compartment•Educational video may be basis for standardization of paraaortic sentinel node dissection.
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28224134/cervical-cancer-screening-in-rural-south-africa-among-hiv-infected-migrant-farm-workers-and-sex-workers
#11
Omara Afzal, Molly Lieber, Peter Dottino, Ann Marie Beddoe
At an HIV clinic in the Limpopo province of South Africa, chart reviews revealed long delays in addressing abnormal Pap smears, difficulty in referrals, poor quality and lost results, and increasing cases of cervical cancer. To address these barriers, a "see and treat" approach to screening was proposed. The objective was to integrate this method into current HIV care offered by local providers and to obtain demographic and risk factor data for use in future educational and intervention programs in the region...
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28217736/gestational-choriocarcinoma-complicated-by-infective-endocarditis-during-chemotherapy
#12
Tadaharu Nakasone, Yutaka Nagai, Yoshihisa Arakaki, Yoshino Kinjyo, Yoichi Aoki
•Little is known about the history of cancer patients complicated with IE.•It is very important to do the chemotherapy without delay for choriocarcinoma.•We report a case of choriocarcinoma complicated by IE during EMA-CO.•An accurate diagnosis/prompt treatment decisions are important for cancer with IE.
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28203627/variations-in-gynecologic-oncology-training-in-low-lic-and-middle-income-mic-countries-lmics-common-efforts-and-challenges
#13
REVIEW
Carolyn Johnston, Joseph S Ng, Ranjit Manchanda, Audrey Tieko Tsunoda, Linus Chuang
Gynecologic cancer, cervical cancer in particular, is disproportionately represented in the developing world where mortality is also high. Screening programs, increased availability of chemotherapy, and an awareness of HIV-related cancers have in part accelerated a need for physicians who can treat these cancers, yet the infrastructure for such training is often lacking. In this paper, we address the variations in gynecology oncology training in LMICs as well as the ubiquitous challenges, in an effort to guide future agendas...
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28180148/leukocytosis-due-to-markedly-elevated-granulocyte-colony-stimulating-factor-levels-in-a-patient-with-endometrial-cancer-case-report-and-literature-review
#14
Leslie H Clark, Stephan Moll, Damon Houghton, Siohban O'Connor, John T Soper
•Granulocyte-colony stimulating factor (GCSF) secretion by gynecologic tumors is rare.•Elevations in serum GCSF can be seen in the absence of tumor GSCF secretion.•Extreme leukocytosis is associated with autocrine tumor growth and poor prognosis.
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28180147/proposed-novel-nomenclature-of-vulvar-smooth-muscle-tumors-a-case-of-smooth-muscle-tumor-of-uncertain-malignant-potential-stump-of-the-vulva
#15
Mathieu Viau, Marie Plante, Marie-Claude Renaud, Katherine Grondin, Chantale Morin
•Clinical experience with smooth muscle tumors of the vulva is limited.•Some tumors present ambiguous histological features concerning for malignancy.•These include infiltration, mitotic activity, size, atypia and tumor cell necrosis.•A case of smooth muscle tumor of the vulva with cellular atypia is presented.•"Smooth Muscle Tumor of Uncertain Malignant Potential" of the vulva is advocated.
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28154838/surgical-anatomy-of-the-ligamentous-mesometrium-and-robotically-assisted-icg-guided-resection-in-cervical-cancer
#16
Rainer Kimmig, Paul Buderath, Peter Rusch, Bahriye Aktas
The ligamentous mesometrium is a 3-dimensional structure consisting of a rectouterine/-vaginal part with attachment to the anterior lateral mesorectum and a sacrouterine part surrounding the mesorectum attached to the pelvic fascia and the mesorectum dorsolaterally. The lymphatic network draining the posterior cervix connected caudally ventrally to the deep venous lymph network of the vascular mesometrium is running at the lateral surface of the sacrouterine part and dorsomedially of the inferior hypogastric plexus; it drains to the deep internal iliac, prespinal and preischiadic nodes...
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28203626/diffuse-peritoneal-leiomyomatosis-status-post-laparoscopic-hysterectomy-with-power-morcellation-a-case-report-with-review-of-literature
#17
Don Nguyen, Rishi Maheshwary, Cassie Tran, Scott Rudkin, Luke Treaster
•Leiomyomatosis following laparoscopic hysterectomy with morcellation is reported.•Parasitic myomas grow in a benign fashion but may be fatal depending on location.•Fibroids are a contraindication for laparoscopic hysterectomy with morcellation.•Containment bags may address intraperitoneal spillage of malignant tissue.
February 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28127584/ovarian-cancer-and-the-immune-system
#18
Thaïs Baert, Ignace Vergote, An Coosemans
Short communication in response to the review of Turner et al. entitled "Ovarian cancer and the immune system - the role of targeted therapies" published in Gynecological Oncology. We believe systemic immune parameters might be a good alternative to tumor biopsy to gain insight in the immunological background of ovarian cancer.
February 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28124023/paget-s-disease-of-the-vulva-a-review-of-89-cases
#19
Cherry O Onaiwu, Mila Pontremoli Salcedo, Suzana A Pessini, Mark F Munsell, Elizabeth E Euscher, Kellie E Reed, Kathleen M Schmeler
The purpose of this study was to retrospectively review the clinical characteristics and outcomes of a series of women with Paget's disease of the vulva. A retrospective review was performed of 89 women with Paget's disease of the vulva evaluated at a single institution between 1966 and 2010. Medical records were reviewed for demographic information, clinical data, pathologic findings, treatment modalities and outcomes. We found that the primary treatment was surgery for 74 (83.1%) patients, with positive margins noted in 70...
February 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28119954/uterine-tumors-resembling-ovarian-sex-cord-tumors-treatment-recurrence-pregnancy-and-brief-review
#20
Sabrina M Schraag, Rosmarie Caduff, Konstantin J Dedes, Daniel Fink, Ana-Maria Schmidt
BACKGROUND: Uterine Tumors Resembling Ovarian Sex Cord Tumors (UTROSCT) are rare tumors of low malignancy. In the past, these tumors were mainly treated by hysterectomy. More recently, some authors have proposed conservative surgical management for women wishing to preserve fertility. This article is the first to report on organ-preserving treatment in the case of recurrence or disease persistence. CASES: We report on three patients with UTROSCT, two of them young, not having completed family planning...
February 2017: Gynecologic Oncology Reports
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