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Gynecologic Oncology Reports

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https://www.readbyqxmd.com/read/28224136/challenges-to-development-of-cervical-and-breast-cancer-program-development-in-post-conflict-liberia-presentation-prepared-for-african-first-ladies-conference-10th-scca-conference-addis-ababa-ethiopia-2016
#1
Ann Marie Beddoe
•Integrating cancer care in post-conflict settings.•Building health worker and infrastructure for cancer care in low resource setting.•Foreword by Her Excellency President Sirleaf, Republic of Liberia.
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28224135/aortic-utero-ovarian-sentinel-nodes-and-left-infrarenal-aortic-lymph-node-dissection-by-icg-supported-navigation
#2
Rainer Kimmig, Peter Rusch, Paul Buderath, Bahriye Aktas
•Visualization of paraaortic sentinel compartments in endometrial cancer•Nerve sparing dissection of left paraaortic infrarenal lymph compartment•Educational video may be basis for standardization of paraaortic sentinel node dissection.
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28224134/cervical-cancer-screening-in-rural-south-africa-among-hiv-infected-migrant-farm-workers-and-sex-workers
#3
Omara Afzal, Molly Lieber, Peter Dottino, Ann Marie Beddoe
At an HIV clinic in the Limpopo province of South Africa, chart reviews revealed long delays in addressing abnormal Pap smears, difficulty in referrals, poor quality and lost results, and increasing cases of cervical cancer. To address these barriers, a "see and treat" approach to screening was proposed. The objective was to integrate this method into current HIV care offered by local providers and to obtain demographic and risk factor data for use in future educational and intervention programs in the region...
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28217736/gestational-choriocarcinoma-complicated-by-infective-endocarditis-during-chemotherapy
#4
Tadaharu Nakasone, Yutaka Nagai, Yoshihisa Arakaki, Yoshino Kinjyo, Yoichi Aoki
•Little is known about the history of cancer patients complicated with IE.•It is very important to do the chemotherapy without delay for choriocarcinoma.•We report a case of choriocarcinoma complicated by IE during EMA-CO.•An accurate diagnosis/prompt treatment decisions are important for cancer with IE.
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28203627/variations-in-gynecologic-oncology-training-in-low-lic-and-middle-income-mic-countries-lmics-common-efforts-and-challenges
#5
REVIEW
Carolyn Johnston, Joseph S Ng, Ranjit Manchanda, Audrey Tieko Tsunoda, Linus Chuang
Gynecologic cancer, cervical cancer in particular, is disproportionately represented in the developing world where mortality is also high. Screening programs, increased availability of chemotherapy, and an awareness of HIV-related cancers have in part accelerated a need for physicians who can treat these cancers, yet the infrastructure for such training is often lacking. In this paper, we address the variations in gynecology oncology training in LMICs as well as the ubiquitous challenges, in an effort to guide future agendas...
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28180148/leukocytosis-due-to-markedly-elevated-granulocyte-colony-stimulating-factor-levels-in-a-patient-with-endometrial-cancer-case-report-and-literature-review
#6
Leslie H Clark, Stephan Moll, Damon Houghton, Siohban O'Connor, John T Soper
•Granulocyte-colony stimulating factor (GCSF) secretion by gynecologic tumors is rare.•Elevations in serum GCSF can be seen in the absence of tumor GSCF secretion.•Extreme leukocytosis is associated with autocrine tumor growth and poor prognosis.
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28180147/proposed-novel-nomenclature-of-vulvar-smooth-muscle-tumors-a-case-of-smooth-muscle-tumor-of-uncertain-malignant-potential-stump-of-the-vulva
#7
Mathieu Viau, Marie Plante, Marie-Claude Renaud, Katherine Grondin, Chantale Morin
•Clinical experience with smooth muscle tumors of the vulva is limited.•Some tumors present ambiguous histological features concerning for malignancy.•These include infiltration, mitotic activity, size, atypia and tumor cell necrosis.•A case of smooth muscle tumor of the vulva with cellular atypia is presented.•"Smooth Muscle Tumor of Uncertain Malignant Potential" of the vulva is advocated.
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28154838/surgical-anatomy-of-the-ligamentous-mesometrium-and-robotically-assisted-icg-guided-resection-in-cervical-cancer
#8
Rainer Kimmig, Paul Buderath, Peter Rusch, Bahriye Aktas
The ligamentous mesometrium is a 3-dimensional structure consisting of a rectouterine/-vaginal part with attachment to the anterior lateral mesorectum and a sacrouterine part surrounding the mesorectum attached to the pelvic fascia and the mesorectum dorsolaterally. The lymphatic network draining the posterior cervix connected caudally ventrally to the deep venous lymph network of the vascular mesometrium is running at the lateral surface of the sacrouterine part and dorsomedially of the inferior hypogastric plexus; it drains to the deep internal iliac, prespinal and preischiadic nodes...
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28203626/diffuse-peritoneal-leiomyomatosis-status-post-laparoscopic-hysterectomy-with-power-morcellation-a-case-report-with-review-of-literature
#9
Don Nguyen, Rishi Maheshwary, Cassie Tran, Scott Rudkin, Luke Treaster
•Leiomyomatosis following laparoscopic hysterectomy with morcellation is reported.•Parasitic myomas grow in a benign fashion but may be fatal depending on location.•Fibroids are a contraindication for laparoscopic hysterectomy with morcellation.•Containment bags may address intraperitoneal spillage of malignant tissue.
February 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28127584/ovarian-cancer-and-the-immune-system
#10
Thaïs Baert, Ignace Vergote, An Coosemans
Short communication in response to the review of Turner et al. entitled "Ovarian cancer and the immune system - the role of targeted therapies" published in Gynecological Oncology. We believe systemic immune parameters might be a good alternative to tumor biopsy to gain insight in the immunological background of ovarian cancer.
February 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28124023/paget-s-disease-of-the-vulva-a-review-of-89-cases
#11
Cherry O Onaiwu, Mila Pontremoli Salcedo, Suzana A Pessini, Mark F Munsell, Elizabeth E Euscher, Kellie E Reed, Kathleen M Schmeler
The purpose of this study was to retrospectively review the clinical characteristics and outcomes of a series of women with Paget's disease of the vulva. A retrospective review was performed of 89 women with Paget's disease of the vulva evaluated at a single institution between 1966 and 2010. Medical records were reviewed for demographic information, clinical data, pathologic findings, treatment modalities and outcomes. We found that the primary treatment was surgery for 74 (83.1%) patients, with positive margins noted in 70...
February 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28119954/uterine-tumors-resembling-ovarian-sex-cord-tumors-treatment-recurrence-pregnancy-and-brief-review
#12
Sabrina M Schraag, Rosmarie Caduff, Konstantin J Dedes, Daniel Fink, Ana-Maria Schmidt
BACKGROUND: Uterine Tumors Resembling Ovarian Sex Cord Tumors (UTROSCT) are rare tumors of low malignancy. In the past, these tumors were mainly treated by hysterectomy. More recently, some authors have proposed conservative surgical management for women wishing to preserve fertility. This article is the first to report on organ-preserving treatment in the case of recurrence or disease persistence. CASES: We report on three patients with UTROSCT, two of them young, not having completed family planning...
February 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28116341/concurrent-chemoradiation-versus-radiotherapy-alone-for-the-treatment-of-locally-advanced-cervical-cancer-in-a-low-resource-setting
#13
Elena Pereira, Hoover Henriquez Cooper, Pedro Guillermo Zelaya, William Creasman, Fredric V Price, Vishal Gupta, Linus Chuang
Our goal was to determine the clinical treatment response following radiation administered with or without chemotherapy for locally advanced cervical cancers in Honduras. This is a retrospective study of patients treated with either concurrent chemoradiation (CCRT) or external beam radiation therapy (EBRT) alone at a hospital in Tegucigalpa, Honduras. 70 Gy of EBRT to the pelvis was given in all cases. Brachytherapy was not available. Chemotherapy was given when available. Extrafascial hysterectomy was performed 6 weeks after completion of treatment in patients with a complete clinical response (cCR)...
February 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28070553/predicted-neoantigen-load-in-non-hypermutated-endometrial-cancers-correlation-with-outcome-and-tumor-specific-genomic-alterations
#14
Sachet A Shukla, Brooke E Howitt, Catherine J Wu, Panagiotis A Konstantinopoulos
Elevated neoantigen load has been previously correlated with improved outcome and response to immune checkpoint blockade in various tumor types. In endometrial cancer, previous studies of neoantigen load prediction have shown that the hypermutated MSI and POLE-mutated tumors harbor significantly higher predicted neoantigen load compared to the hypomutated CN-low/endometrioid and CN-high/serous-like tumors. Here, we report that predicted neoantigen load may be a prognostic factor in hypomutated endometrial cancers, both in CN-low/endometrioid and CN-high/serous-like tumors...
February 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28070552/long-term-survival-after-anterior-pelvic-exenteration-and-total-vaginectomy-for-recurrent-endometrial-carcinoma-with-metastatic-inguinal-nodes-at-the-time-of-surgery
#15
Benjamin Margolis, Sun Woo Kim, Dennis S Chi
•Pelvic exenteration can be used in patients with multifocal recurrence.•Ability to achieve negative margins remains a necessity for pelvic exenteration.•Individualized treatments are essential for those with recurrent malignancy.
February 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28054022/low-grade-endometrial-stromal-sarcoma-with-extensive-sex-cord-differentiation-heterologous-elements-and-complex-atypical-hyperplasia-case-report-and-review-of-literature
#16
Abby M Richmond, Andrew J Rohrer, Susan A Davidson, Miriam D Post
•Endometrial stromal sarcoma (ESS) may have sex cord differentiation, usually focal.•Diagnosis of ESS is difficult when variant morphology predominates.•Prognosis differs between ESS and UTROSCT; therefore, distinction is critical.•Extensive tumor sampling is mandatory to identify neoplastic endometrial stroma.•Sex cord differentiation may be associated with endometrial hyperplasia.
February 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28050597/cardiophrenic-lymph-node-metastasis-in-low-grade-serous-ovarian-adenocarcinoma
#17
Tasha Serna-Gallegos, Nicolas Gallegos, Robert E Bristow
•Cardiophrenic lymph node metastasis in low-grade ovarian carcinoma is rare.•Two cases presented here identify clinical strategies needing further attention.•Low-grade disease is treated with surgery given high chemotherapeutic resistance.•Preoperative awareness of lymph node metastasis allows for optimal debulking.•Identifying radiologic evidence of distant metastasis improves patient outcomes.
February 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28050596/an-ovarian-mature-cystic-teratoma-evolving-in-squamous-cell-carcinoma-a-case-report-and-review-of-the-literature
#18
REVIEW
C Goudeli, A Varytimiadi, N Koufopoulos, J Syrios, E Terzakis
Mature cystic teratomas (MCT), also known as dermoid cysts, are the most common ovarian germ cell tumors and the most common ovarian neoplasms in patients younger than 20 years. Malignant transformation (MT) is a rare complication of MCTs which may occur in 1-2% of the cases. Squamous cell carcinoma (SCC) is the most frequent histology arising from MCTs and its appearance depends on diverse risk factors such as patient's age, the size of the tumor and levels of serum tumor markers. Diagnosis and treatment constitute a big challenge due to the rarity and the aggressive course of this entity...
February 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28050595/cervical-cancer-prevention-training-in-south-east-asian-lmics
#19
Joseph Soon-Yau Ng, Ida Ismail-Pratt
The Association of Southeast Asian Nations (ASEAN) is a confederation of 10 sovereign states occupying approximately 1.7 million square miles of Southeast Asia with an estimated population of just under 630 million. Southeast Asia continues to have one of the world's highest rates of cervical cancer-related death. Organised training in cervical cancer screening is essential but lacking in low to middle income countries (LMICs). Systematic training of local doctors is an essential part of an effective screening program and an effective strategy to reduce cervical cancer-related mortality...
February 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28018956/reproductive-counseling-contraception-and-unplanned-pregnancy-in-fertile-women-treated-by-gynecologic-oncologists
#20
Sarah M Crafton, Courtney D Lynch, David E Cohn, Eric L Eisenhauer
We sought to identify how gynecologic oncologists approach reproductive counseling for their fertile, reproductive age patients, and their experience with unplanned pregnancies. Members of the Society of Gynecologic Oncology (SGO) were surveyed electronically regarding consistency of counseling patterns of contraception and fertility concerns, most and least common contraceptive methods utilized, referral patterns, and incidence of unplanned pregnancy. Of the 1424 SGO members identified, 261 participated in the questionnaire, yielding a response rate of 18%...
February 2017: Gynecologic Oncology Reports
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