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Gynecologic Oncology Reports

Franco Muggia, David Kudlowitz
No abstract text is available yet for this article.
November 2018: Gynecologic Oncology Reports
Sara M Drayer, Jessica J Shank
Infectious diseases can present similar to ovarian cancer and occur concomitantly with ovarian pathology. With increased worldwide travel and migration of populations, infections endemic to developing countries can emerge in the United States. We present 2 cases of infectious diseases mimicking ovarian carcinomatosis. Two Filipino women presented with abdominal distension and had evaluations suggestive of advanced gynecologic malignancy. The first patient underwent surgery and was found to have peritoneal tuberculosis...
November 2018: Gynecologic Oncology Reports
Lauren C Hand, Talia M Maas, Nadia Baka, Rebecca J Mercier, Patrick J Greaney, Norman G Rosenblum, Christine H Kim
Objectives: We aimed to analyze the outcomes of patients who underwent vulvectomy with subsequent V-Y fasciocutaneous flap reconstruction. Methods: All medical records of all patients who underwent vulvectomies with V-Y fasciocutaneous flap reconstruction from January 2007 to June 2016 were retrospectively reviewed. Patient clinical and surgical data, demographics, and outcomes were abstracted. Results: Of the 27 patients, 42 flaps were transferred...
November 2018: Gynecologic Oncology Reports
Michiko Nonaka, Seiya Sato, Daiken Osaku, Mayumi Sawada, Akiko Kudoh, Jun Chikumi, Shinya Sato, Tetsuro Oishi, Tasuku Harada
Bevacizumab (Bev) is an antiangiogenic drug used to treat various malignances, including ovarian cancer (OC). Bev is generally well-tolerated; however, it has a characteristic toxicity profile. In particular, gastrointestinal perforation (GIP) is a rare but serious side effect that can be lethal. A 55-year-old woman with recurrent OC had an episode of GIP during third-line chemotherapy comprising Bev and topotecan (TPT). Bev was discontinued while TPT was continued as monotherapy. Three months after discontinuation of Bev, the patient presented with left lower abdominal pain and was diagnosed with a second GIP...
November 2018: Gynecologic Oncology Reports
William T Jaegle, Erin A Keyser, Lynn Messersmith, Robert O Brady, Caela Miller
Background: Sex cord tumors with annular tubules (SCTAT) are a rare (2%) subtype of ovarian sex cord-stromal tumor. SCTATs are usually cured at time of diagnosis by surgical resection with an oophorectomy. SCTATs have a 100%(disease related) five-year survival. One third of SCTAT tumors are associated with Peutz-Jeghers syndrome. Literature review discovered only two published cases of extra-ovarian SCTAT. Due to the rarity there is no standard treatment for extraovarian SCTATs. Case: A 39-year-old para-1 female with a symptomatic fibroid uterus, heavy menstrual bleeding, and a history of a uterine myomectomy, underwent an elective total abdominal hysterectomy...
November 2018: Gynecologic Oncology Reports
Josette C Dawkins, Gregory K Lewis, Eugene P Toy
Cervical cancer is the most common gynecologic malignancy worldwide and the third most common gynecologic cancer in the USA. Improved screening methods such as liquid-based cytology accompanied by Human Papilloma Virus (HPV) co-testing have contributed to a declining incidence of cervical cancer. There are approximately 13,000 new cases per year in the United States, accounting for 4200 deaths (Siegel et al., 2011). Pelvic organ prolapse increases with age, obesity and parity. In the absence of bothersome urinary, gastrointestinal or pressure symptoms, patients may choose conservative management options...
November 2018: Gynecologic Oncology Reports
Mário Bruno Santos, Rita Félix Soares, Filipe Basto
Women undergoing pelvic lymphadenectomy and radiation therapy for gynaecological cancer are prone to acute and often recurrent cellulitis as a consequence of compromised lymphatic circulation. Vaginal intercourse can trigger the infection, a condition named streptococcal sex syndrome (SSS). We report a 63-year old female patient with a history of pelvic lymphadenectomy and radiation therapy for gynaecological cancer. She presented to the obstetrics/gynaecology department for vaginal haemorrhage during sexual intercourse the day before...
November 2018: Gynecologic Oncology Reports
Michelle D S Lightfoot, Katharine M Esselen, Miriam J Haviland, John L Dalrymple, Christopher S Awtrey, Leslie A Garrett, Michele R Hacker, Fong W Liu
•Gynecologic oncologists face multiple barriers in participating in global health.•Several barriers may be addressed at the institutional level.•Most global health experiences involved direct patient care, while only a small proportion involved research.•Gynecologic oncologists receive little structured training in global health.
November 2018: Gynecologic Oncology Reports
Mackenzie W Sullivan, Susan C Modesitt
•A woman with recurrent ovarian cancer presented with rectal bleeding and cramping abdominal pain.•CT showed ileocolic intussusception.•In ovarian cancer, intussusception requires surgery whereas other bowel obstructions are initially treated conservatively.
November 2018: Gynecologic Oncology Reports
Javier Burbano, Alejandra Salazar-González, Carolina Echeverri, Gabriel Rendón, Monica Gaviria, Rene Pareja
Skin metastases are a rare event in patients with cervical cancer. One form of such metastasis is carcinomatous lymphangitis, which is a rare presentation of skin metastases. Here we report a woman with cervical cancer diagnosed cutaneous lymphangitic carcinomatosis.
November 2018: Gynecologic Oncology Reports
Wissam Hanayneh, Jason Starr, Thomas J George, Hiral Parekh
Gastrointestinal stromal tumors (GISTs) are rare tumors of gastrointestinal (GI) tract with mesenchymal cell origin. Extragastrointestinal stromal tumors (EGISTs) are unusual tumors that exhibit the same immunohistochemical and genetic abnormalities as GISTs and most commonly affect the omentum and mesentery. EGISTs of the pelvis and the female reproductive system are exceedingly rare and a frequent diagnostic pitfall. In this report, we present two cases of EGISTs along with a review of the literature.
August 2018: Gynecologic Oncology Reports
Nguyen Vu Quoc Huy, Vo Van Khoa, Le Minh Tam, Truong Quang Vinh, Nguyen Sanh Tung, Cao Ngoc Thanh, Linus Chuang
Objectives: To evaluate the validity of serum CA-125, Human Epididymis protein 4 (HE4) and Risk of Malignancy Algorithm (ROMA) at standard and optimal cut-offs, in preoperative prediction of epithelial ovarian carcinoma (EOC) in Vietnam. Subjects and methods: Cross-sectional, descriptive study on 277 patients with ovarian masses hospitalized at the OBGYN Departments, Hue University Hospital and Hue Central Hospital, Vietnam, from 01/2016 to 11/2017. All patients had measurements of serum CA-125 by Elecsys 2010 system and HE4 by immunoassay ARCHITECT® HE4 kits; ROMA calculated, and preoperative malignancy risk estimated...
August 2018: Gynecologic Oncology Reports
Yu Yoshida, Eisuke Kaneki, Masako Kijima, Keisuke Kodama, Shinichiro Yamaguchi, Hiroshi Yagi, Masafumi Yasunaga, Tatsuhiro Ohgami, Ichiro Onoyama, Kaoru Okugawa, Hideaki Yahata, Kenzo Sonoda, Kiyoko Kato
•This report shows very rare cases of small cell carcinoma of the ovary, hypercalcemic type and pulmonary type.•Their chemo sensitivity is quite different. These two cases followed opposite clinical courses.•The first case (SCOHT) progressed rapidly, and showed resistance to chemotherapy and radiotherapy.•The second case (SCOPT) showed sensitivity to chemotherapy and radiotherapy although recurrence was repeated.
August 2018: Gynecologic Oncology Reports
Kohshiro Nakao, Harumichi Banno, Tsuyoshi Kondo, Shinya Hirabuki, Hiromasa Sasaki, Tsutomu Hoshiba
•Paraganglioma is sometimes suspected as lymph node metastasis or lymph node recurrence of various malignant tumors.•Retroperitoneoscopic surgery is a valid approach to treat the tumor, located above the renal vein.•Resection using retroperitoneoscopic surgery without catecholamine-related complications is possible.
August 2018: Gynecologic Oncology Reports
J Olpin, L Chuang, J Berek, D Gaffney
Cervix cancer is the fourth most common cancer globally but the second most cancer in women in resource-limited countries. It has remained a clinically-staged neoplasm as per the International Federation of Gynecology and Obstetrics staging classification. As the imaging machines are becoming more available worldwide, the resource-stratified guidelines recommended the inclusion of imaging whenever possible to guide treatment planning. In this report, the utility of imaging in low- and middle-income countries for diagnosis and treatment of cancer of the cervix will be reviewed...
August 2018: Gynecologic Oncology Reports
Lisa N Abaid, John S Cupp, Miles Chang, Steven R Beanes, Bram H Goldstein
Endometriosis is a condition wherein an ectopic layer of endometrial tissue arises in an extra-uterine location, often effecting significant pelvic pain and infertility. While very uncommon, there have been reported cases of endometriosis undergoing malignant transformation, frequently involving the ovaries and seldom in extra-gonadal regions. We recount a case depicting a 63 year-old woman who presented with an apparent inguinal hernia in 2017; she was ultimately diagnosed with a pelvic side wall clear cell carcinoma and attendant metastatic disease to the medial groin, which emanated from endometriosis...
August 2018: Gynecologic Oncology Reports
S Yost, A Hoekstra
Objective: Evaluate the characteristics and screening history of patients diagnosed with cervical cancer over age 65. Methods: A retrospective review of 34 patients who were diagnosed with cervical cancer after the age of 65 at a single community cancer center between 2006 and 2016 was performed. Data collected included screening history, method of detection, stage, and survival. Results: Between 2006 and 2016, 346 women were diagnosed with cervical cancer at a single community cancer center, 34 (9...
August 2018: Gynecologic Oncology Reports
Mari Minagawa, Mamoru Maeda, Masahito Shimauchi, Hirohisa Kishi, Shinichi Teshima
Serous borderline tumors (SBTs) are nonaggressive and have excellent prognosis. Furthermore, SBTs with micropapillary pattern (SBT-MP) are known to be associated with a higher recurrence rate, microinvasions and invasive implants compared to typical SBTs, and these characteristics have adverse effects on prognosis. Here, we report a case of SBT with micropapillary pattern (SBT-MP) that developed 6 recurrences over 30 years after primary surgery. The patient was a 70 year-old woman. At 41 years of the age she underwent total abdominal hysterectomy, bilateral salpingo-oophorectomy, partial omentectomy and pelvic lymphadenectomy and was found to have an SBT-MP involving the right ovary (International Federation of Gynecology and Obstetrics 2014, stage IC2)...
August 2018: Gynecologic Oncology Reports
Matthew Cowan, Tara Suntum, Andrea D Olivas, Melody Perpich, Mark A Applebaum, Ricardo R Lastra, S Diane Yamada
•Embryonal rhabdomyosarcoma of the uterine cervix and ovarian Sertoli-Leydig cell tumors are associated with DICER1 mutation• DICER1 -associated tumors should prompt genetic counseling and testing•Somatic and germline genetic mutation profiles can be used to differentiate second primary from recurrent tumors.
August 2018: Gynecologic Oncology Reports
Bryan J Ager, Dolores Gallardo-Rincón, David Cantú de León, Adriana Chávez-Blanco, Linus Chuang, Alfonso Dueñas-González, Eva Gómez-García, Roberto Jerez, Anuja Jhingran, Mary McCormack, Linda Mileshkin, Carlos Pérez-Plasencia, Marie Plante, Andrés Poveda, David K Gaffney
Cervical cancer is the fourth most common cancer in women with 85% of the mortality burden occurring in less-developed regions of the world. The Cervix Cancer Research Network (CCRN) was founded by the Gynecologic Cancer InterGroup (GCIG) with a mission to improve outcomes in cervix cancer by increasing access to high-quality clinical trials worldwide, with particular attention to less-developed, underrepresented sites. The CCRN held its second international educational symposium in Mexico City with ninety participants from fifteen Latin America countries in January 2017...
August 2018: Gynecologic Oncology Reports
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