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Advances in Medicine

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https://www.readbyqxmd.com/read/27872896/comparison-of-clinical-and-radiologic-outcome-of-adolescent-idiopathic-scoliosis-treated-with-hybrid-hook-screw-instrumentation-versus-universal-clamp-system
#1
Ebrahim Ghayem Hassankhani, Farzad Omidi-Kashani, Shahram Moradkhani, Golnaz Ghayem Hassankhani, Mohammad Taghi Shakeri
Background. In surgical treatment of adolescent idiopathic scoliosis (AIS), hybrid universal clamp system has been used by some authors. We aimed to compare the clinical and radiologic outcome of hybrid universal clamp with hybrid thoracic hook lumbar screw. Methods. A prospective study was performed on 56 consecutive patients with AIS, who had alternatively undergone a posterior spinal fusion and instrumentation with hybrid thoracic hook lumbar screw system (28 patients: group A) and hybrid universal clamp system (28 patients: group B) between June 2006 and January 2014 at Imam Reza University Hospital and had been followed up for more than two years...
2016: Advances in Medicine
https://www.readbyqxmd.com/read/27847860/morphology-of-anterolateral-ligament-of-the-knee-a-cadaveric-observation-with-clinical-insight
#2
Bhagath Kumar Potu, Abdel Halim Salem, Marwan F Abu-Hijleh
Background. The morphology and function of anterolateral ligament (ALL) of the knee are not clearly understood even today with all the sophisticated techniques available. There have been differing descriptions of the ALL of the knee in literature, and not all of them have been named or described clearly. Aim. The present study was undertaken to provide a clear structure/relationship description on ALL. Materials and Methods. We used 24 formalin-fixed cadaveric limbs. Knee regions of the all the limbs were neatly dissected and the ALL was exposed...
2016: Advances in Medicine
https://www.readbyqxmd.com/read/27833937/external-validation-of-the-cancer-of-the-prostate-risk-assessment-postsurgical-score-for-prediction-of-disease-recurrence-after-radical-prostatectomy
#3
Taha Numan Yıkılmaz, Erdem Öztürk, Eşref Oğuz Güven, Halil Başar
Objective. The cancer of the prostate risk assessment (CAPRA-S) postsurgical score predicts recurrence, metastasis, and cancer-specific survival after radical prostatectomy (RP). We evaluated the relation between CAPRA-S score and biochemical recurrence (BCR) in prostate cancer after RP in our clinic. Materials and Methods. This study was performed on 203 patients with prostate carcinoma who underwent open RP and regional lymph node dissection in our clinic between 2008 and 2013. We calculated the CAPRA-S scores including prostate-specific antigen (PSA) at diagnosis, pathology Gleason score, surgical margin, seminal vesicle invasion, extracapsular extension, and lymph node involvement...
2016: Advances in Medicine
https://www.readbyqxmd.com/read/27830176/lipopolysaccharide-induced-spatial-memory-and-synaptic-plasticity-impairment-is-preventable-by-captopril
#4
Azam Abareshi, Akbar Anaeigoudari, Fatemeh Norouzi, Mohammad Naser Shafei, Mohammad Hossein Boskabady, Majid Khazaei, Mahmoud Hosseini
Introduction. Renin-angiotensin system has a role in inflammation and also is involved in many brain functions such as learning, memory, and emotion. Neuroimmune factors have been proposed as the contributors to the pathogenesis of memory impairments. In the present study, the effect of captopril on spatial memory and synaptic plasticity impairments induced by lipopolysaccharide (LPS) was investigated. Methods. The rats were divided and treated into control (saline), LPS (1 mg/kg), LPS-captopril (LPS-Capto; 50 mg/kg captopril before LPS), and captopril groups (50 mg/kg) before saline...
2016: Advances in Medicine
https://www.readbyqxmd.com/read/27822492/changes-of-nitric-oxide-and-peroxynitrite-serum-levels-during-drug-therapy-in-patients-with-obsessive-compulsive-disorder
#5
Leila Kouti, Mehdi Sayyah, Parisa Mosallanezhad, Sara Kooti, Maryam Aghakoochakzadeh, Kaveh Eslami
Objectives. Some studies have shown that increased nitric oxide (NO) concentrations may be associated with obsessive-compulsive disorder (OCD). In a few animal researches, enhanced synthesis of NO had reversed the effect of selective serotonin reuptake inhibitors (SSRIs). The present study tries to find the effect of treatment with SSRIs on NO serum levels and its product peroxynitrite. Patients and Methods. Patients diagnosed with OCD who are candidates of receiving SSRIs entered this study. Two blood samples were taken from subjects, prior to drug therapy and after the patients had shown some improvements due to their regimen...
2016: Advances in Medicine
https://www.readbyqxmd.com/read/27819022/dietary-energy-density-renal-function-and-progression-of-chronic-kidney-disease
#6
Mohammad Hossein Rouhani, Mojgan Mortazavi Najafabadi, Ahmad Esmaillzadeh, Awat Feizi, Leila Azadbakht
Background. There is evidence of the association between dietary energy density and chronic diseases. However, no report exists regarding the relation between DED and chronic kidney disease (CKD). Objective. To examine the association between dietary energy density (DED), renal function, and progression of chronic kidney disease (CKD). Design. Cross-sectional. Setting. Three nephrology clinics. Subjects. Two hundred twenty-one subjects with diagnosed CKD. Main Outcome Measure. Dietary intake of patients was assessed by a validated food frequency questionnaire...
2016: Advances in Medicine
https://www.readbyqxmd.com/read/27819021/nonrecurrent-laryngeal-nerve-in-the-era-of-intraoperative-nerve-monitoring
#7
Emin Gurleyik, Gunay Gurleyik
Nonrecurrent laryngeal nerve (non-RLN) is an anatomical variation increasing the risk of vocal cord palsy. Prediction and early identification of non-RLN may minimize such a risk of injury. This study assessed the effect of intraoperative neuromonitoring (IONM) on the detection of non-RLN. A total of 462 (236 right) nerves in 272 patients were identified and totally exposed, and all intraoperative steps of IONM were sequentially applied on the vagus nerve (VN) and RLN. Right predissection VN stimulation at a distal point did not create a sound signal in three cases (3/236; 1...
2016: Advances in Medicine
https://www.readbyqxmd.com/read/27800544/prevalence-and-correlates-of-peripheral-arterial-disease-in-nigerians-with-type-2-diabetes
#8
D O Soyoye, R T Ikem, B A Kolawole, K S Oluwadiya, R A Bolarinwa, O J Adebayo
Background. Peripheral arterial disease (PAD) is a major risk factor for nonhealing foot ulcers in people with diabetes. A number of traditional risk factors have been reported to be associated with PAD; however, there may be a need to consider nontraditional risk factors especially in some vulnerable populations. This study determined the prevalence and risk factors associated with PAD in diabetics. Methods. One hundred and fifty type 2 diabetics and an equal number of age- and sex-matched apparently healthy controls were studied...
2016: Advances in Medicine
https://www.readbyqxmd.com/read/27777969/a-study-to-analyze-different-patterns-of-quid-usage-among-subjects-with-oral-submucous-fibrosis-in-mangalore-population
#9
Vidya A Holla, L K Chatra, Prashanth Shenai, Devika Shetty, Ashwini Baliga
Aim and Objectives. Oral submucous fibrosis (OSF) is a potentially malignant disorder associated with the usage of areca nut. Usage of processed forms of areca nut is popular among the youth and its carcinogenic effects are not well known. Due to large immigrant population, various patterns of areca nut usage are seen. The aim of this study is to assess the various quid chewing patterns and their association with severity of OSF. Materials and Methods. A cross-sectional study was carried out with 250 cases clinically and histologically diagnosed as having OSF lesion that were selected and subjected to a detailed habit history which was recorded through preformed questionnaire...
2016: Advances in Medicine
https://www.readbyqxmd.com/read/27774507/reactive-oxygen-species-a-key-hallmark-of-cardiovascular-disease
#10
Nisha Panth, Keshav Raj Paudel, Kalpana Parajuli
Cardiovascular diseases (CVDs) have been the prime cause of mortality worldwide for decades. However, the underlying mechanism of their pathogenesis is not fully clear yet. It has been already established that reactive oxygen species (ROS) play a vital role in the progression of CVDs. ROS are chemically unstable reactive free radicals containing oxygen, normally produced by xanthine oxidase, nicotinamide adenine dinucleotide phosphate oxidase, lipoxygenases, or mitochondria or due to the uncoupling of nitric oxide synthase in vascular cells...
2016: Advances in Medicine
https://www.readbyqxmd.com/read/27738653/the-protocol-of-choice-for-treatment-of-snake-bite
#11
Afshin Mohammad Alizadeh, Hossein Hassanian-Moghaddam, Nasim Zamani, Mitra Rahimi, Mohammad Mashayekhian, Behrooz Hashemi Domeneh, Peyman Erfantalab, Ali Ostadi
The aim of the current study is to compare three different methods of treatment of snake bite to determine the most efficient one. To unify the protocol of snake bite treatment in our center, we retrospectively reviewed files of the snake-bitten patients who had been referred to us between 2010 and 2014. They were contacted for follow-up using phone calls. Demographic and on-arrival characteristics, protocol used for treatment (WHO/Haddad/GF), and outcome/complications were evaluated. Patients were entered into one of the protocol groups and compared...
2016: Advances in Medicine
https://www.readbyqxmd.com/read/27699203/control-of-pedicle-screw-placement-with-an-electrical-conductivity-measurement-device-initial-evaluation-in-the-thoracic-and-lumbar-spine
#12
Olaf Suess, Markus Schomacher
Aim. Transpedicular screw fixation is widely used in spinal surgery. But the insertion of pedicle screws can sometimes be challenging because of the variability in pedicle size and the proximity of nerve roots. Methods. We detected intraoperatively the sensitivity for iatrogenic pedicel perforation with a hand-held electronic conductivity measurement device (ECD) that measures electrical conductivity of tissue-medium surrounding the instrument tip. ECD was used to guide the placement of 84 pedicle screws in 15 patients undergoing surgery for tumor or degenerative spinal disease at various spinal levels from T8 to L5...
2016: Advances in Medicine
https://www.readbyqxmd.com/read/27689135/topical-colchicine-gel-versus-diclofenac-sodium-gel-for-the-treatment-of-actinic-keratoses-a-randomized-double-blind-study
#13
Gita Faghihi, Azam Elahipoor, Fariba Iraji, Shadi Behfar, Bahareh Abtahi-Naeini
Introduction. Actinic keratoses (AKs), a premalignant skin lesion, are a common lesion in fair skin. Although destructive treatment remains the gold standard for AKs, medical therapies may be preferable due to the comfort and reliability .This study aims to compare the effects of topical 1% colchicine gel and 3% diclofenac sodium gel in AKs. Materials and Methods. In this randomized double-blind study, 70 lesions were selected. Patients were randomized before receiving either 1% colchicine gel or 3% diclofenac sodium cream twice a day for 6 weeks...
2016: Advances in Medicine
https://www.readbyqxmd.com/read/27689134/the-relationship-between-body-mass-index-and-depression-among-high-school-girls-in-ahvaz
#14
Ashraf Tashakori, Forough Riahi, Amin Mohammadpour
Objective. Today, obesity and depression are two major illnesses that are on the rise all over the world and threaten human health. This research was done to determine the relationship between Body Mass Index (BMI) and depression among Ahvaz high school female students. Method. In a descriptive-analytical study using stratified random sampling, 400 female high school students in academic year of 2013-2014 were picked and their height and weight were measured. BMI was classified based on World Health Organization classification...
2016: Advances in Medicine
https://www.readbyqxmd.com/read/27652291/cyp4f2-rs2108622-gene-polymorphism-association-with-age-related-macular-degeneration
#15
Ruta Sakiene, Alvita Vilkeviciute, Loresa Kriauciuniene, Vilma Jurate Balciuniene, Dovile Buteikiene, Goda Miniauskiene, Rasa Liutkeviciene
Background. Age-related macular degeneration is the leading cause of blindness in elderly individuals where aetiology and pathophysiology of age-related macular degeneration are not absolutely clear. Purpose. To determine the frequency of the genotype of rs2108622 in patients with early and exudative age-related macular degeneration. Methods. The study enrolled 190 patients with early age-related macular degeneration, 181 patients with exudative age-related macular degeneration (eAMD), and a random sample of 210 subjects from the general population (control group)...
2016: Advances in Medicine
https://www.readbyqxmd.com/read/27648468/blatchford-score-is-superior-to-aims65-score-in-predicting-the-need-for-clinical-interventions-in-elderly-patients-with-nonvariceal-upper-gastrointestinal-bleed
#16
Khalid Abusaada, Fnu Asad-Ur-Rahman, Vladimir Pech, Umair Majeed, Shengchuan Dai, Xiang Zhu, Sally A Litherland
Background. Blatchford and AIMS65 scores were developed to risk stratify patients with upper gastrointestinal bleed (UGIB). We sought to assess the performance of Blatchford and AIMS65 scores in predicting outcomes in elderly patients with nonvariceal UGIB. Methods. A retrospective cohort study of elderly patients (over 65 years of age) with nonvariceal UGIB admitted to a tertiary care center. Primary outcome was a combined outcome of in-hospital mortality, need for any therapeutic endoscopic, radiologic, or surgical intervention, rebleeding within 30 days, or blood transfusion...
2016: Advances in Medicine
https://www.readbyqxmd.com/read/27642628/antifungal-susceptibility-patterns-of-candida-species-recovered-from-endotracheal-tube-in-an-intensive-care-unit
#17
Elham Baghdadi, Sadegh Khodavaisy, Sassan Rezaie, Sara Abolghasem, Neda Kiasat, Zahra Salehi, Somayeh Sharifynia, Farzad Aala
Aims. Biofilms formed by Candida species which associated with drastically enhanced resistance against most antimicrobial agents. The aim of this study was to identify and determine the antifungal susceptibility pattern of Candida species isolated from endotracheal tubes from ICU patients. Methods. One hundred forty ICU patients with tracheal tubes who were intubated and mechanically ventilated were surveyed for endotracheal tube biofilms. Samples were processed for quantitative microbial culture. Yeast isolates were identified to the species level based on morphological characteristics and their identity was confirmed by PCR-RFLP...
2016: Advances in Medicine
https://www.readbyqxmd.com/read/27610404/evaluation-of-hla-g-14%C3%A2-bp-ins-del-and-3142g-c-polymorphism-with-susceptibility-and-early-disease-activity-in-rheumatoid-arthritis
#18
Mohammad Hashemi, Mahnaz Sandoughi, Seyed Amirhossein Fazeli, Gholamreza Bahari, Maryam Rezaei, Zahra Zakeri
Purpose/Background. Mounting evidence designates that HLA-G plays a role in the regulation of inflammatory processes and autoimmune diseases. There are controversial reports concerning the impact of HLA-G gene polymorphism on rheumatoid arthritis (RA). This study was aimed at examining the impact of 14 bp ins/del and +3142G>C polymorphism with susceptibility and early disease activity in RA patients in a sample of the Iranian population. Methods. This case-control study was done on 194 patients with RA and 158 healthy subjects...
2016: Advances in Medicine
https://www.readbyqxmd.com/read/27597986/the-protective-effects-of-alpha-lipoic-acid-and-coenzyme-q10-combination-on-ovarian-ischemia-reperfusion-injury-an-experimental-study
#19
Ahmet Ali Tuncer, Mehmet Fatih Bozkurt, Tulay Koken, Nurhan Dogan, Mine Kanat Pektaş, Didem Baskin Embleton
Objective. This study aims to evaluate whether alpha-lipoic acid and/or coenzyme Q10 can protect the prepubertal ovarian tissue from ischemia-reperfusion injury in an experimental rat model of ovarian torsion. Materials and Methods. Forty-two female preadolescent Wistar-Albino rats were divided into 6 equal groups randomly. The sham group had laparotomy without torsion; the other groups had torsion/detorsion procedure. After undergoing torsion, group 2 received saline, group 3 received olive oil, group 4 received alpha-lipoic acid, group 5 received coenzyme Q10, and group 6 received both alpha-lipoic acid and coenzyme Q10 orally...
2016: Advances in Medicine
https://www.readbyqxmd.com/read/27579346/prevalence-of-schistosoma-mansoni-infection-in-four-health-areas-of-kisantu-health-zone-democratic-republic-of-the-congo
#20
R Khonde Kumbu, K Mbanzulu Makola, Lu Bin
Background. Schistosomiasis is a public health problem in Democratic Republic of the Congo but estimates of its prevalence vary widely. The aim of this study was to determine prevalence of Schistosoma mansoni infection and associated risk factors among children in 4 health areas of Kisantu health zone. Methods. A cross-sectional study was carried out in 4 health areas of Kisantu health zone. 388 children randomly selected were screened for S. mansoni using Kato Katz technique and the sociodemographic data was collected...
2016: Advances in Medicine
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