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European Journal of Radiology Open

Héla Fourati, Emna Ellouze, Mourad Ahmadi, Dhouha Chaari, Fatma Kamoun, Ines Hsairi, Chahnez Triki, Zeineb Mnif
l-2-Hydroxyglutaric (l-2-HG) aciduria is a rare inherited metabolic disease usually observed in children. Patients present a very slowly progressive deterioration with cerebellar ataxia, mild or severe mental retardation, and various other clinical signs including extrapyramidal and pyramidal symptoms, and seizures Goffette et al. [1]. This leukencephalopathy was first described in 1980 Duran et al. [2]. Brain magnetic resonance imaging (MRI) demonstrates nonspecific subcortical white matter (WM) loss, cerebellar atrophy and changes in dentate nuclei and putamen Steenweg et al...
2016: European Journal of Radiology Open
Gang Wu, Teng Jin, Ting Li, Xiaoming Li
PURPOSE: To evaluate the diagnostic value of time resolved magnetic resonance angiography with interleaved stochastic trajectory (TWIST) using Gadobutrol for preoperative evaluation of lower extremity tumors. MATERIALS AND METHODS: This prospective study was approved by the local Institutional Review Board. 50 consecutive patients (31 men, 19 women, age range 18-80 years, average age 42.7 years) with lower extremity tumors underwent TWIST and computed tomography angiography (CTA)...
2016: European Journal of Radiology Open
Clemens G Kaiser, Pascal Baltzer, Anna K Kaiser, Julia Krammer, Michael Uder, Werner A Kaiser, Matthias Dietzel
PURPOSE: To examine "constant lesion sharpness" as a morphological diagnostic sign in the differential diagnosis between benign and malignant lesions. MATERIAL AND METHODS: This prospective study had institutional review board approval and was HIPAA compliant. In total 1014 consecutive patients were examined (mean age 55 years ± 13 years) and evaluated in our University hospital towards the morphological shape of the lesion borders. The "Constant sharpness Sign" was defined as a lesion remaining continuously sharp for the duration of the dynamic scan...
2016: European Journal of Radiology Open
Jens Altenbernd, Axel Wetter, Michael Forsting, Lale Umutlu
PURPOSE: The aim of this prospective study was to examine the diagnostic value of dual-energy CT (DECT) in the assessment of response of HCC after radioembolisation (RE). MATERIAL AND METHODS: 40 HCC patients with 82 measurable target lesions were included in this study. At baseline and follow-up examination target lesions were evaluated with (IU), AASLD and Choi measurement criteria. Disease control was defined as the sum of complete response (CR), partial response (PR), progression disease (PD) and stable disease (SD)...
2016: European Journal of Radiology Open
Xing Hu, Jiangmin Zhao, Haishan Qian, Guangyan Du, Margaret Kelly, Hua Yang
PURPOSE: Once lung cancer is detected due to clinical symptoms or by being visible on chest X-ray, it is usually high stage and non-operable. In order to improve mortality rates in lung cancer, low-dose CT (LDCT) screening of "high risk" individuals is gaining popularity. However, the rate of malignancy in LDCT detected sub-centimetre lung nodules is not clear. We aimed to analyze surgically resected specimens in this patient group to explore cost effectiveness and recommendations for clinical management of these nodules...
2016: European Journal of Radiology Open
Thomas Henzler, Nils Vogler, Bettina Lange, Franz Dally, Mathias Meyer, Stefan O Schoenberg, Maliha Sadick
OBJECTIVES: To prospectively evaluate the diagnostic value and radiation dose of time-resolved CT-Angiography (4D-CTA) in pediatric patients with venous malformations using 3rd generation dual-source CT (DSCT) at 70 kVp tube voltage. METHODS: Between November 2014 and August 2015, seven children (2 male, 5 female; median age, 9 years; range 3-12 years) with suspected peripheral, non-cerebral, venous malformations were included in this feasibility study and underwent US, MRI and 4D-CTA...
2016: European Journal of Radiology Open
Oğuzhan Özdemir, Yavuz Metin, Nurgül Orhan Metin, Ali Küpeli, Süleyman Kalcan, Filiz Taşçı
OBJECTIVE: We aimed to search the contribution of diffusion-weighted imaging (DWI) in follow-up of patients with acute appendicitis associated inflammatory appendiceal mass (IAM). DWI was used as a monitoring imaging method to assess the response of medical treatment. MATERIALS AND METHODS: 19 patients (mean age, 37+-13.1; age range, 19-69; M/F: 10/9), presented with clinical, laboratory and computed tomography (CT) findings suggestive of IAM were enrolled prospectively in this study...
2016: European Journal of Radiology Open
Carmen Sebastià, Alejandro D Sotomayor, Blanca Paño, Rafael Salvador, Marta Burrel, Albert Botey, Carlos Nicolau
PURPOSE: To evaluate the accuracy of unenhanced magnetic resonance angiography (U-MRA) using balanced steady-state free precession (SSFP) sequences with inversion recovery (IR) pulses for the evaluation of renal artery stenosis. MATERIALS AND METHODS: U-MRA was performed in 24 patients with suspected main renal artery stenosis. Two radiologists evaluated the quality of the imaging studies and the ability of U-MRA to identify hemodynamically significant main renal artery stenosis (RAS) defined as a stenosis ≥50% when compared to gold standard tests: contrast-enhanced magnetic resonance angiography (CE-MRA) (18 patients) or digital subtraction arteriography (DSA) (6 patients)...
2016: European Journal of Radiology Open
In Chul Nam
OBJECTIVE: To evaluate the association between Non-alcoholic fatty liver disease (NAFLD) with renal stone disease detected on computed tomography (CT). METHOD: A total 1812 patients who underwent abdomen-pelvis CT in July 2015 were included in this study. The inclusion criteria for NAFLD were as follows: (i) lower average Hounsfield unit (HU) of hepatic right lobe, left medial and lateral segment when compared with that of spleen, (ii) patients who having urolithiasis in kidneys, ureters and urinary bladder, and (iii) patients underwent abdomen-pelvis CT including noncontrast image...
2016: European Journal of Radiology Open
Lorenzo Faggioni, Michela Gabelloni, Vinicio Napoli, Francesco Iorio, Antonio Chella, Davide Caramella
Kommerell's diverticulum (KD) is defined as a bulbous dilatation of the origin of an aberrant subclavian artery due to a remnant of the left fourth aortic arch. We report the case of an asymptomatic woman in whom progressive thrombosis of the KD extending to the prevertebral tract of an aberrant right subclavian artery was detected at multidetector computed tomography imaging for lung cancer staging performed before and after the beginning of chemotherapy. Reversed blood flow in the ipsilateral vertebral artery due to subclavian steal phenomenon was also observed by color Doppler ultrasound examination...
2016: European Journal of Radiology Open
Holger Wenz, Máté E Maros, Mathias Meyer, Joshua Gawlitza, Alex Förster, Holger Haubenreisser, Stefan Kurth, Stefan O Schoenberg, Christoph Groden, Thomas Henzler
OBJECTIVES: To prospectively evaluate image quality and organ-specific-radiation dose of spiral cranial CT (cCT) combined with automated tube current modulation (ATCM) and iterative image reconstruction (IR) in comparison to sequential tilted cCT reconstructed with filtered back projection (FBP) without ATCM. METHODS: 31 patients with a previous performed tilted non-contrast enhanced sequential cCT aquisition on a 4-slice CT system with only FBP reconstruction and no ATCM were prospectively enrolled in this study for a clinical indicated cCT scan...
2016: European Journal of Radiology Open
Stephanie Zesch, Stephanie Panzer, Wilfried Rosendahl, John W Nance, Stefan O Schönberg, Thomas Henzler
PURPOSE: The aim of this study was to systematically reinvestigate the first human mummy that was ever analyzed with X-ray imaging in 1896, using dual-source computed tomography (DSCT) in order to compare the earliest and latest imaging technologies, to estimate preservation, age at death, sex, anatomical variants, paleopathological findings, mummification, embalming and wrapping of the child mummy from ancient Egypt. Radiocarbon dating was used to determine the mummy's age and to specify the child's living period in the Egyptian chronology...
2016: European Journal of Radiology Open
S T Laroia, Ajeet Bhadoria, Yamini Venigalla, G K Chibber, Chagan Bihari, Archana Rastogi, S K Sarin
OBJECTIVE: To investigate dual-energy spectral CT in characterization of hepatocellular Carcinoma (HCC) in patients with chronic liver disease. METHODS: Dynamic computed tomography (CT) was performed in 3600 patients (2879 males; 721 females, mean age 50.9 ± 11.9 years) with working clinical diagnosis of liver cirrhosis for hepatocellular carcinoma screening and other clinical indications. The study was conducted over a period of 3 years. During dynamic CT scanning, spectral (monochromatic) and routine (polychromatic) CT acquisitions were obtained on a single tube, dual energy, 64 slice multi-detector CT scanner...
2016: European Journal of Radiology Open
Foteini Christidi, Efstratios Karavasilis, Kostantinos Samiotis, Sotirios Bisdas, Nikolaos Papanikolaou
PURPOSE: Diffusion tensor imaging (DTI) enables in vivo reconstruction of white matter (WM) pathways. Considering the emergence of numerous models and fiber tracking techniques, we herein aimed to compare, both quantitatively and qualitatively, the fiber tracking results of four DTI software (Brainance, Philips FiberTrak, DSI Studio, NordicICE) on the reconstruction of representative WM tracts. MATERIALS AND METHODS: Ten healthy participants underwent 30-directional diffusion tensor imaging on a 3T-Philips Achieva TX MR-scanner...
2016: European Journal of Radiology Open
Pietro Valerio Foti, Giuseppe Privitera, Sebastiano Piana, Stefano Palmucci, Corrado Spatola, Roberta Bevilacqua, Luigi Raffaele, Vincenzo Salamone, Rosario Caltabiano, Gaetano Magro, Giovanni Li Destri, Pietro Milone, Giovanni Carlo Ettorre
PURPOSE: to investigate the added value of qualitative and quantitative evaluation of diffusion weighted (DW) magnetic resonance (MR) imaging in response assessment after neoadjuvant chemo-radiotherapy (CRT) in patients with locally advanced rectal cancer (LARC). METHODS: 31 patients with LARC (stage ≥ T3) were enrolled in the study. All patients underwent conventional MRI and DWI before starting therapy and after neoadjuvant CRT. All patients underwent surgery; pathologic staging represented the reference standard...
2016: European Journal of Radiology Open
Yuko Nakamura, Toru Higaki, Yuji Akiyama, Wataru Fukumoto, Kenji Kajiwara, Yoko Kaichi, Yukiko Honda, Daisuke Komoto, Fuminari Tatsugami, Makoto Iida, Toshifumi Ohmoto, Shuji Date, Kazuo Awai
PURPOSE: To investigate the utility of computed 3T diffusion-weighted imaging (c-DWI) for the diagnosis of non-complicated hepatic cysts with a focus on the T2 shine-through effect. MATERIALS AND METHODS: In 50 patients with non-complicated hepatic cysts we acquired one set of DWIs (b-value 0 and 1000 s/mm(2)) at 1.5T, and two sets at 3T (b-value 0 and 1000 s/mm(2), TE 70 ms; b-value 0 and 600 s/mm(2), TE 60 ms). We defined the original DWIs acquired with b = 1000 s/mm(2) at 1...
2016: European Journal of Radiology Open
Henning D Popp, Mathias Meyer, Susanne Brendel, Wiltrud Prinzhorn, Nicole Naumann, Christel Weiss, Wolfgang Seifarth, Stefan O Schoenberg, Wolf-K Hofmann, Thomas Henzler, Alice Fabarius
PURPOSE: Computed tomography (CT) scans are an important source of ionizing irradiation (IR) in medicine that can induce a variety of DNA damage in human tissues. With technological improvements CT scans at reduced absorbed doses became feasible presumably lowering genotoxic side effects. MATERIALS AND METHODS: For measuring DNA damage we performed γH2AX foci microscopy in peripheral blood mononuclear cells (PBMC) after exposure to reduced and conventional absorbed radiation doses using 3rd generation dual-source CT (DSCT) technology...
2016: European Journal of Radiology Open
M C Kleijwegt, A G L van der Mey, F T Wiggers-deBruine, M J A Malessy, M J P van Osch
OBJECTIVE: The added value of perfusion MRI for decision-making in vestibular schwannoma (VS) patients is unknown. MRI offers two perfusion methods: the first employing contrast agent (dynamic susceptibility contrast (DSC)-MRI) that provides information on cerebral blood volume (CBV) and cerebral blood flow (CBF), the second by magnetic labeling of blood (arterial spin labeling (ASL)-MRI), providing CBF-images. The goal of the current study is to investigate whether DSC and ASL perfusion MRI provides complimentary information to current anatomical imaging in treatment selection process of VS...
2016: European Journal of Radiology Open
Clemens G Kaiser, Pascal Baltzer, Anna K Kaiser, Julia Knaudt, Thomas Henzler, Werner A Kaiser, Matthias Dietzel
PURPOSE: To demonstrate our primary findings, indicating perirenal edema as a first imaging sign towards primary hypertension. METHODS: Out of 3190 consecutive MR-Mammography (MRM) examinations, 777 were performed with an additional body array coil. Incidentally, "perirenal edema" could be linked to a patient history of hypertension. We Therefore specifically further observed the correlation. RESULTS: Of 777 patients 86 (11%) patients showed the perirenal edema sign (PES)...
2016: European Journal of Radiology Open
Clemens G Kaiser, Pascal Baltzer, Matthias Dietzel, Anna K Kaiser, Thomas Henzler, Werner A Kaiser, Julia Knaudt
PURPOSE: During clinical routine, we retrospectively discovered diagnostic criteria for "focal mastitis" in MR-Mammography (MRM). The aim of this study was to prospectively evaluate these criteria. METHODS: 1975 consecutive patients were examined between 01/2010 and 12/2011. 29 patients fit the diagnostic criteria of focal mastitis. RESULTS: In follow-up scans, 28 patients showed a complete remission of the previous findings. One patient was followed-up with persisting findings, which could histologically be correlated to an area of DCIS after biopsy...
2016: European Journal of Radiology Open
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