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Oxford Medical Case Reports

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https://www.readbyqxmd.com/read/28721224/erratum-intense-flu-like-symptoms-in-women-using-menstrual-devices-always-think-of-staphylococcal-toxic-shock-syndrome
#1
Marianneta Chatzopoulou, Theocharis Koufakis, Evdokia Ntava, Ioannis Gabranis, Maria Tsiakalou
[This corrects the article DOI: 10.1093/omcr/omx020.].
July 2017: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28690859/case-report-of-a-lupus-patient-with-a-severe-flare-and-miliary-tuberculosis-need-for-proper-guidelines-for-management
#2
Masooma Hashmat, Ramsa Suhail Rana, Tafazzul-E-Haque Mahmud, Aflak Rasheed, Ata Ur Rehman, Syed Ali Rukh Pirzada, Muhammad Ammad Asghar, Sadia Asif, Amjad Ali
Systemic lupus erythematosus (SLE) is an autoimmune disease that is frequently treated with high doses of corticosteroids and other immunosuppressive drugs. Thus patients with SLE are at increased risk for infections with several pathogens including Mycobacterium tuberculosis. There are no established guidelines available for treatment of tuberculosis in SLE patients with high disease activity due to lack of relevant studies and management based more on physician expertise. We report a case of a young SLE patient with high disease activity index (SLEDAI19) as evidenced by the presence of a vasculitic rash, non-healing ulcer on forearm and proteinuria of >1 g/d along with miliary tuberculosis...
July 2017: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28690858/topical-rapamycin-for-facial-angiofibromas-in-tuberous-sclerosis-complex
#3
Gilles Safa
Facial angiofibromas are a common cutaneous manifestation of tuberous sclerosis complex. Although angiofibromas are usually asymptomatic, they can be highly disfiguring and can have a significant impact on patient quality of life. Treatment for facial angiofibromas is challenging. Recently, topical rapamycin has been proposed as an effective option to treat angiofibromas. Herein is reported a case of a 27-year-old woman whose facial angiofibromas were successfully treated with topical rapamycin without relevant side effects...
July 2017: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28680649/aorto-right-ventricular-fistula-a-rare-complication-of-abiotrophia-endocarditis
#4
Priyanka Bhattacharya, Aasim Mohammed, Eddy Mizrahi
A 41-year-old African male presented with worsening dyspnea and cachexia concerning for congestive heart failure. Transesophageal echocardiogram revealed a large mass attached to the aortic valve leaflet, mass attached to the flail anterior mitral valve leaflet, severe pulmonary hypertension and dilatation of the aortic root along with fistula between the right coronary aortic cusp and the right ventricular (RV) outflow tract. Blood cultures grew Abiotrophia Defectiva (AD) sensitive to vancomycin. Patient underwent emergent surgical closure of aorto RV fistula and aortic root replacement along with pulmonary and mitral valve replacement...
July 2017: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28680648/treating-refractory-post-herpetic-anti-n-methyl-d-aspartate-receptor-encephalitis-with-rituximab
#5
Christine Strippel, Constanze Mönig, Kristin S Golombeck, Andre Dik, Kathrin Bönte, Stjepana Kovac, Andreas Schulte-Mecklenbeck, Heinz Wiendl, Sven G Meuth, Andreas Johnen, Catharina C Gross, Nico Melzer
Herpes simplex virus-1 has been identified as the trigger factor in certain cases of NMDA-receptor autoimmune encephalitis. We report on a 67-year-old female patient, who was severely affected by post-herpetic NMDA-receptor autoimmune encephalitis. Her symptoms did not improve under methylprednisolone pulse therapy and plasma exchange under acyclovir prophylaxis. She received protein A immunoadsorption and a long-term immunosuppression with rituximab. Under treatment, activated T-cells as well as B- and plasma cells decreased in peripheral blood and cerebrospinal fluid, and anti-NMDA-R IgG titers in serum and cerebrospinal fluid declined with near complete cessation of intrathecal autoantibody synthesis...
July 2017: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28638625/early-eculizumab-use-in-atypical-haemolytic-uraemic-syndrome-in-a-jehovah-s-witness-refusing-blood-products
#6
May Al-Shaghana, Andrew Bentall, Mark D Jesky, William Lester, Graham Lipkin
Thrombotic microangiopathy (TMA) is characterized by microscopic angiopathic haemolytic anaemia, thrombocytopenia and organ injury. Supportive therapies include the use of blood products. Recently the terminal complement inhibitor eculizumab has been approved in atypical haemolytic uraemic syndrome (aHUS) in some countries. We report the case of a 23-year-old female Jehovah's Witness presenting with vaginal haemorrhage from thrombocytopaenia, severe anaemia (nadir Hb 28 g/L) and anuric acute kidney injury with TMA secondary to aHUS...
June 2017: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28638624/kikuchi-fujimoto-disease-a-case-report-of-a-multi-drug-resistant-grueling-disease
#7
Alexey Youssef, Rahaf Ali, Kinan Ali, Zuheir AlShehabi
Histiocytic necrotizing lymphadenitis or Kikuchi-Fujimoto disease (KFD) is characterized by its rare occurrence. Mostly prevalent among Asian women, KFD manifests with lymphadenopathy-affecting mostly cervical and rarely generalized or retroperitoneal regions-in addition to fever. It is a self-limited disease that resolves within 1-4 months, responding remarkably to glucocorticosteroids or hydroxychloroquine. However, some rare cases prove to be unresponsive to the previously mentioned therapies. Here is a description of a case of KFD affecting a 67-year-old Syrian woman with a history of hypothyroidism due to iodine-deficiency...
June 2017: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28616248/lymphangioleiomyomatosis-an-explosive-presentation-of-a-rare-disease
#8
Faye Pais, Mohamed Fayed, Timothy Evans
Lymphangioleiomyomatosis (LAM) is a rare cystic lung disease, commonly affecting women in the reproductive age group. Exacerbation of pre-existing disease is common during pregnancy likely due to the up-regulation of estrogen and progesterone receptors present within the proliferating smooth muscle cells. This case highlights a dramatic presentation of LAM for the first time in pregnancy, its rapid progression during gestation, and a partial resolution with delivery. The unusual radiographic imaging in this patient, lacked the characteristic cystic lesions commonly associated with LAM, but instead demonstrated a dense interstitial pattern with micronodular expansion of the interlobular septa suggesting severe lymphatic obstruction...
June 2017: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28580160/oxcarbazepine-induced-stevens-johnson-syndrome-a-pediatric-case-report
#9
Burçin Beken, Ceren Can, Aysegül Örencik, Nuray Can, Mehtap Yazıcıoğlu
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis are two rare but life-threatening diseases characterized by detachment of epidermis, bullous skin lesions and mucous membrane erosions. Anti-epileptic drugs are highly suspected to be the causative agents. Although carbamazepine (CBZ) is the most associated anti-epileptic drug, oxcarbazepine (OXC), which is a monohydrated derivative of CBZ, is proposed to be safer because of the different metabolism of the two drugs. Herein, we report a case of SJS induced by oxcarbazepine...
June 2017: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28580159/azithromycin-induced-cholestatic-hepatitis
#10
Apostolos Koffas, Iain M Murray-Lyon, Roger Williams
Since its introduction >20 years ago, Azithromycin has been widely used owing to its broad spectrum and good tolerability, especially when used for <7 days. In literature, there are only very few, sporadic reports available of patients developing cholestatic hepatitis following treatment with it. The current case study describes a 69-year old patient, with a medical history that included significant alcohol consumption, who presented with jaundice following a 3-day course of Azithromycin. Following a transjugular liver biopsy, he was managed with a short course of corticosteroids and his liver function gradually improved and finally normalized ~2 months after discontinuation of Azithromycin...
June 2017: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28580158/opana-induced-thrombotic-microangiopathy-masquerading-as-thrombotic-thrombocytopenic-purpura
#11
Byung H Ban, Ashish Verma, Maria Tudor, Jigme Sethi
Opana (oxymorphone) is a powerful semi-synthetic opioid agonist used for chronic pain management that is ingested orally. However, improper injection of Opana can lead to a rare and fatal blood disorder known as thrombotic microangiopathy. Opana-induced thrombotic microangiopathy can be easily mistaken for thrombotic thrombocytopenic purpura (TTP), leading to the initiation of therapeutic plasma exchange. Current literature has conflicting views on the necessity of therapeutic plasma exchange for the treatment of Opana-induced thrombotic microangiopathy...
June 2017: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28580157/incidental-finding-of-a-primary-thyroid-tuberculosis
#12
Andrés Ortiz-Flores, Francesca Gioia, Laura Montánez-Fernández, Elisa Santacruz, Pilar Martín-Dávila, Héctor Pian-Arias, José I Botella-Carretero
Thyroid tuberculosis (TT) is a very rare condition, even in countries where tuberculosis is endemic. However, the prevalence of tuberculosis has increased worldwide and thyroid involvement can be a primary manifestation of the disease. We present the case of a 43-year-old patient with this diagnosis and perform a review of the related literature. After searching for similar case reports in Western Europe since 2010 we identified six cases in four countries. TT should be considered in the differential diagnosis of a thyroid nodule...
June 2017: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28580156/castleman-s-disease-with-tafro-syndrome-a-case-report-from-syria
#13
Sami Alhoulaiby, Basel Ahmad, Ali Alrstom, Mayssoun Kudsi
Castleman's disease is a rare disorder, yet a rarer newly described syndrome called TAFRO syndrome was discovered to accompany it. TAFRO represents the constellation of symptoms (Thrombocytopenia, Anasarca, MyeloFibrosis, Renal failure, Organomegaly). Most cases were described in Japan. We present the first case of TAFRO syndrome in Syria. A 58-year-old Caucasian male with no relevant history presented with fatigue, oliguria, decreased platelets, increased creatinine level, hepatosplenomegaly, ascites, pitting edema and lymph node enlargement...
June 2017: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28580155/intense-flu-like-symptoms-in-women-using-menstrual-devices-always-think-of-staphylococcal-toxic-shock-syndrome
#14
Marianneta Chatzopoulou, Theocharis Koufakis, Evdokia Ntava, Ioannis Gabranis, Maria Tsiakalou
No abstract text is available yet for this article.
May 2017: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28580154/parry-romberg-syndrome-presenting-with-a-giant-intracranial-aneurysm-a-case-report
#15
Ilse H de Lange, Anna Mt van Oploo, Feico Jj Halbertsma, F George Roos, Levinus A Bok
A giant intracranial aneurysm was diagnosed in a 10-year-old girl when she developed a right abducens nerve palsy. The aneurysm was treated successfully. Six years later, however, she presented with a progressive en coup de sabre deformity, leading to the diagnosis Parry Romberg Syndrome (PRS), a rare diagnosis characterized by hemifacial atrophy of skin, subcutaneous tissue, skeletal muscle and bones and often associated with various non-specific intracerebral abnormalities. In this patient retrospective analysis of computed tomography and magnetic resonance imaging imaging indeed revealed intracerebral calcifications and aspecific white matter lesions...
May 2017: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28580153/complete-pathological-response-of-multiple-huge-liver-metastases-of-colon-cancer-a-case-report
#16
Keishi Hakoda, Masanori Yoshimitsu, Manabu Emi, Ichiro Omori, Toshihiko Kohashi, Mayumi Kaneko, Hideki Ohdan, Naoki Hirabayashi
We report a case of a pathological complete response (pCR) with chemotherapy for multiple huge liver metastases from colon cancer. A 59-year-old woman presented with anorexia and weight loss. Laboratory tests revealed elevated liver enzyme levels and tumor markers. A computed tomography/positron emission tomography-computed tomography scan revealed a transverse colon tumor and unresectable liver masses measuring 9.0 cm in maximum diameter in segments 7 and 8, with another mass in segment 6. She underwent laparoscopic colectomy and was administered FOLFOX + BV...
May 2017: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28580152/brugada-phenocopy-in-a-patient-with-acute-pulmonary-embolism-presenting-with-recurrent-syncope
#17
Nixiao Zhang, Tong Liu, Gary Tse, Shuyu Yu, Huaying Fu, Gang Xu, Changyu Zhou, Chengzong Zhang, Guangping Li
Brugada phenocopy (BrP) refers to a group of clinical conditions that have etiologies distinct from Brugada syndrome (BrS). Although both demonstrate features of ST-segment elevation in the right precordial leads on the electrocardiogram (ECG), one must be distinguished from the other as their treatment options are different. We report a male patient who presented with recurrent syncope with a Brugada and a S1Q3T3 pattern on the ECG. Acute pulmonary embolism (APE) complicated by BrS was suspected. Twenty-four hours Holter monitoring did not demonstrate any evidence of ventricular arrhythmias...
May 2017: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28480047/isolated-sacral-and-pelvic-tb-abscess-an-enigmatic-tale-of-a-ubiquitous-pathogen
#18
Sunil Munakomi
No abstract text is available yet for this article.
May 2017: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28480046/steroid-induced-tumour-lysis-syndrome-in-small-cell-lung-cancer
#19
Fasihul Khan, Shazeen Ayub, Qurrat Mehmood, Syed Fayyaz Hussain
A 64-year-old male presented to hospital with breathlessness and weight loss. Ultrasound-guided biopsy of supraclavicular lymph node confirmed a diagnosis of small-cell lung cancer. The patient was started on Dexamethasone 8 mg twice daily for symptom control while awaiting urgent oncology assessment. Three days later he was admitted with acute kidney injury and worsening breathlessness. Biochemical changes confirmed tumour lysis syndrome (TLS) that had occurred following steroid therapy. He was given allopurinol followed by rasburicase...
May 2017: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28473923/air-in-the-portal-vein-where-computed-tomography-saved-a-patient-s-life
#20
Samer Al Hadidi, Kinza Tareen
No abstract text is available yet for this article.
April 2017: Oxford Medical Case Reports
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