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Oxford Medical Case Reports

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https://www.readbyqxmd.com/read/28058108/basosquamous-carcinoma-appearance-and-reality
#1
Rakesh L Anand, Damian Collins, Anna Chapman
Basosquamous carcinoma (BsC) is a controversial entity and both a diagnostic and therapeutic challenge. BsC has mixed histopathological characteristics of both basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). BCC and SCC display characteristic histopathology and behaviour; on the other hand, BsC is a rare tumour, which has variable morphology and displays less predictable behaviour. An early diagnosis of BsC is important due to the particularly aggressive nature of the tumour, the increased likelihood of recurrence and the potential for metastasis...
January 2017: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28058107/toxoplasmosis-with-chorioretinitis-in-an-hiv-infected-child-with-no-visual-complaints-importance-of-fundus-examination
#2
Noella Maria Delia Pereira, Ira Shah, Mamatha Lala
Central nervous system lesions are common in HIV-infected patients. In the combination anti-retroviral therapy (ART) era, Toxoplasma reactivation has been observed only in patients with unrecognized HIV infection or refusing therapy. We present the case of 10-year-old girl with AIDS who initially presented with pneumonia. She was treated for pneumonia and thereafter started on ART as her CD4 count was low. However, 5 days after starting ART she presented with left ptosis and right-sided monoparesis. She was diagnosed with neurotoxoplasmosis and responded successfully to pyrimethamine-sulfadoxine therapy...
January 2017: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28031857/giant-mature-teratoma-in-the-mediastinum-presenting-with-rapid-growth
#3
Kohei Fujita, Kazuki Hayashi, Makoto Motoishi, Satoru Sawai, Tsuyoshi Terashima, Tadashi Mio
Teratomas are primary germ-cell tumours in the mediastinum. Although they are generally slow-growing and asymptomatic, rapid growth causing life-threatening complications can occur. Sebaceous secretion, insulin production, chorionic gonadotropin secretion and pancreatic enzyme secretion are the presumptive causes of tumour progression. Only few cases of rapidly growing teratomas have been reported previously. Here, we present a case of a giant mature teratoma in the mediastinum that presented with rapid growth and compare the characteristics of this case with those of previous cases...
December 2016: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28031856/small-bowel-obstruction-attributable-to-phytobezoar
#4
Nasrin Razavianzadeh, Behzad Foroutan, Farhad Honarvar, Mohammad Forozeshfard
Small bowel obstruction (SBO) is a common condition encountered in surgical practice. Literature shows divers and many different etiologies for intestinal obstruction. However, bezoars are rarely reported as an etiological factor. A bezoar happens most commonly in patients with impaired gastrointestinal motility. There are four types of bezoars: phytobezoars, trichobezoars, pharmacobezoars and lactobezoars. The most common type is phytobezoars, which are composed of undigested fiber from vegetables or fruits especially persimmons...
December 2016: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28031855/neurologic-symptoms-as-the-only-manifestation-of-b12-deficiency-in-a-young-patient-with-normal-hematocrit-mcv-peripheral-blood-smear-and-homocysteine-levels
#5
Panagiota Voukelatou, Ioannis Vrettos, Andreas Kalliakmanis
B12 deficiency is associated with several neurological manifestations. It is well documented that neurologic symptoms due to B12 deficiency may sometimes present in the absence of anemia. However, in most cases there are several indicating factors like megaloblastic changes in complete blood count, hypersegmentated neutrophils or macroovalocytes in peripheral blood smear and abnormal homocysteine levels. In this report, we describe a case of a 32-year-old man with neurological symptomatology as the only manifestation of B12 deficiency with normal hematocrit, mean cell volume, peripheral blood smear and homocysteine levels...
December 2016: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28031854/endobronchial-pleomorphic-adenoma
#6
Syed Rizwan Ali, Andrea Valeria Arrossi, Atul C Mehta, Laura Frye, Peter Mazzone, Francisco Almeida
Pleomorphic adenomas are the most common tumors of the salivary glands. Rarely, they occur as benign lesions in the lungs in both the central airways and the lung parenchyma. Herein, we present a case of a 60-year-old smoker who was incidentally found to have an endobronchial mass while undergoing evaluation for a lung nodule. During bronchoscopy, a smooth globular nodule was identified at the main carina and removed using electrocautery snare. Histopathology examination revealed this to be a pleomorphic adenoma...
December 2016: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28031853/lithium-therapy-in-comorbid-temporal-lobe-epilepsy-and-cycloid-psychosis
#7
Paul Brown, Sridhar Kashiviswanath, Alison Huynh, Naveen Allha, Ken Piaggio, Saddichha Sahoo, Ankur Gupta
The treatment of post-ictal psychosis has foundered on uncertainty in diagnosis of psychotic phenotypes, and equivocal efficacy of first and second generation antipsychotics. This article presents a case history of comorbid temporal lobe epilepsy and psychosis, suggests the applicability of the continental, cycloid psychosis diagnostic conceptualization to post-ictal psychoses, and demonstrates the efficacy of lithium in their treatment. Clinical studies of comorbidity of epilepsy and psychosis offer great potential as a basis for modelling brain-mind relationships, and neuropsychiatric nosology, pathophysiology and treatment...
December 2016: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28031852/linezolide-induced-hairy-tongue
#8
João Braga-Simões, Laura Azevedo Santos
No abstract text is available yet for this article.
December 2016: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28031851/a-good-excuse-for-skipping-the-test-electrical-storm-in-a-teenager
#9
Patrícia Rodrigues, António Pinheiro-Vieira, Marília Loureiro, Sílvia Álvares, Diana Anjo, Carla Roque, Maria João Sousa, Severo Torres
We describe the case of a teenager with a structurally normal heart that presented with torsades de pointes and cardiac arrest. He had a history of epilepsy in childhood, mild cognitive impairment and cognitive visual dysfunction. The baseline electrocardiogram had prominent J waves and a marked early repolarization pattern in all the leads, with normal QT interval. We discuss the differential diagnosis for this interesting case, as well as the patient's management.
December 2016: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28031850/isolated-mycobacterium-kansasii-wound-infection-and-osteomyelitis-in-an-immunocompetent-patient
#10
Tarek Turk, Mohamed Faher Almahmoud, Khulood Raslan
Mycobacterium kansasii is a slow growing acid-fast non-tuberculosis mycobacterium. It most commonly causes pulmonary disease with tuberculosis-like manifestations. Mycobacterium kansasii-induced skin and soft tissue infections (SSTIs) are very uncommon, especially in the absence of obvious risk factors. In this report, we present a rare case of M. kansasii-associated SSTI complicated by tendonitis and osteomyelitis in an immunocompetent patient. This case highlights the importance of considering non-tuberculosis mycobacteria while investigating chronic, relapsing, non-healing SSTIs and osteomyelitis...
November 2016: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28031849/a-classical-case-of-non-bacterial-thrombotic-endocarditis-from-pancreatic-adenocarcinoma-presenting-as-multiple-strokes-myocardial-infarction-and-acute-limb-ischaemia
#11
Ching-Hui Sia, Joline Si Jing Lim, Kian Keong Poh, Tan Min Chin
Non-bacterial thrombotic endocarditis (NBTE) classically presents in the context of pancreatic adenocarcinomas. Echocardiography is useful to investigate for valvular vegetations, and institution of early treatment is crucial as this can be complicated by multiple systemic emboli, leading to significant morbidity or mortality in serious cases. Treatment options involve anticoagulation with unfractionated heparin, and the role of surgical intervention is unclear. In this report, we describe a classical case of a middle-aged lady with unresectable pancreatic adenocarcinoma who developed NBTE complicated by multiple systemic emboli...
November 2016: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28031848/spontaneous-hepatic-artery-dissection-a-rare-presentation-of-fibromuscular-dysplasia
#12
Kevin Y C Su, Melanie L Stanhope, Brendan P W Kaufman
Fibromuscular dysplasia (FMD) is a rare condition that causes structural compromise of the blood vessel presenting either as an incidental radiological finding, dissection or stenosis usually of the renal or craniocervical arteries. Seldom, patients present with spontaneous dissection in visceral arteries and there are few reports of hepatic involvement. This report outlines the case of a 43-year-old female who presented with severe right upper quadrant pain with a subsequent diagnosis of FMD manifesting as spontaneous hepatic artery dissection...
November 2016: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28031847/infiltrative-thyrotoxicosis-an-unusual-case-of-diffuse-large-b-cell-lymphoma
#13
Michael T McCarthy, Michael Keyes, James O'Hare, Neville Shine, Rajnish K Gupta
Thyrotoxicosis is most commonly caused by Graves' disease, toxic multinodular goitre, a functioning thyroid adenoma, or thyroiditis. Extrinsic infiltrative conditions affecting the thyroid gland are typically destructive, and associated with thyroid hypofunction. We describe the case of a 61-year-old woman who presented to our hospital with symptoms of thyrotoxicosis, neck swelling and thyroid function tests consistent with hyperthyroidism. An ultrasound revealed a multinodular goitre with retrosternal extension, but CT imaging suggested thyroid gland infiltration, with cervical lymphadenopathy...
November 2016: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28031846/refractory-rheumatoid-vasculitis-a-therapeutic-dilemma
#14
EDITORIAL
Richard A Watts, Eleana Ntatsaki
No abstract text is available yet for this article.
November 2016: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28031845/dengue-shock-syndrome
#15
Sreenivasa Rao Sudulagunta, Mahesh Babu Sodalagunta, Mona Sepehrar, Shiva Kumar Bangalore Raja, Aravinda Settikere Nataraju, Mounica Kumbhat, Deepak Sathyanarayana, Siddharth Gummadi, Hemanth Kumar Burra
Dengue fever is a mosquito-borne arthropod-borne viral (arboviral) tropical disease in humans affecting 50-528 million people worldwide. The acute abdominal complications of dengue fever are acute appendicitis, acute pancreatitis, acute acalculous cholecystitis and non-specific peritonitis. Acute pancreatitis with new onset diabetes in dengue shock syndrome (DSS) is very rarely reported. We describe a case of 30-year-old man admitted in intensive care unit and was diagnosed with DSS with RT-PCR, NS1 antigen and dengue IgM antibody being positive...
November 2016: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28031844/refractory-rheumatoid-vasculitis
#16
Ashok Kumar, Anshul Goel, Mehul Lapsiwala, Suman Singhal
Systemic rheumatoid vasculitis (SRV) can develop in rheumatoid arthritis of long duration and high disease activity. It most commonly manifests as cutaneous vasculitis and mononeuritis multiplex. This can involve any organ of the body and carries very high mortality. We report a case of a young male who had rheumatoid arthritis for the past 15 years and became refractory to standard drugs and anti-TNF agents. He subsequently developed SRV, which started as mononeuritis multiplex. Disease progressed to result in gangrene of hands and feet despite receiving intravenous cyclophosphamide...
November 2016: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/27812374/pok%C3%A3-mon-go-cardiovascular-benefit-or-injury-risk
#17
Pranev Sharma, Vassilios Vassiliou
No abstract text is available yet for this article.
October 2016: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/27721981/polyarteritis-nodosa-with-a-chronic-relapsing-course
#18
Ashok Kumar, Anshul Goel, Mehul Lapsiwala
Polyarteritis nodosa is a medium artery vasculitis that can cause fatal complications. It commonly follows an acute monophasic course that may remit after treatment or cause serious morbidity or death. A 24-year-old patient described here had many vasculitic episodes in the past 16 years causing infarction of different organs. The last episode was most serious which caused mononeuritis multiplex, digital gangrene, bowel gangrene and subsequent perforations. There was strong clinical suspicion of this disease right from the beginning...
October 2016: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/27713831/potential-perils-of-peri-pok%C3%A3-mon-perambulation-the-dark-reality-of-augmented-reality
#19
Bellal Joseph, David G Armstrong
Recently, the layering of augmented reality information on top of smartphone applications has created unprecedented user engagement and popularity. One augmented reality-based entertainment application, Pokémon Go (Pokémon Company, Tokyo, Japan) has become the most rapidly downloaded in history. This technology holds tremendous promise to promote ambulatory activity. However, there exists the obvious potential for distraction-related morbidity. We report two cases, presenting simultaneously to our trauma center, with injuries sustained secondary to gameplay with this augmented reality-based application...
October 2016: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/27699056/management-of-anthracycline-extravasation-into-the-pleural-space
#20
Rachael Chang, Nick Murray
Anthracycline extravasation is a feared complication of intravenous (i.v.) chemotherapy due to the tissue toxicity of this group of drugs. We describe a 54-year-old woman with history of stage IIIa breast cancer, receiving adjuvant chemotherapy consisting of doxorubicin and cyclophosphamide. The chemotherapy was administered through a Poweport(®) device, the position of which was confirmed with fluoroscopy and function confirmed by flushing the line. Urgent intervention was required as patient was symptomatic and experienced severe right-sided pleuritic chest pain...
October 2016: Oxford Medical Case Reports
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