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Oxford Medical Case Reports

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https://www.readbyqxmd.com/read/29657741/a-curious-case-of-idiopathic-subcutaneous-emphysema
#1
Mayanka Kamboj, Vikrampal Bhatti, Abhilash Koratala
No abstract text is available yet for this article.
April 2018: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29657740/mechanical-prosthetic-heart-valves-here-to-stay
#2
EDITORIAL
Sofia Kassou, Vassilios S Vassiliou
No abstract text is available yet for this article.
April 2018: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29644083/acute-interstitial-pneumonia-as-first-presentation-of-anti-synthetase-syndrome-an-atypical-case
#3
Kalimullah Jan, Melonie Kannamma Sriranganathan
Anti-synthetase syndrome is characterized by myositis associated with interstitial lung disease (ILD), the usual pattern of ILD being non-specific interstitial pneumonia type or usual interstitial pneumonia. We report a case of anti-synthetase syndrome presenting as acute interstitial pneumonia which is reported only once before. With this case, we emphasize the need to consider anti-synthetase syndrome even in patients presenting with acute onset ILD. Physicians should raise their index of suspicion in this clinical context as timely diagnosis, early treatment, and a multidisciplinary approach is paramount for optimal care of these patients...
April 2018: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29593878/methicillin-resistant-staphylococcus-aureus-prostatic-abscess-after-traumatic-rectal-injury
#4
Joud Jarrah, Varun Samji, Meron Meshesha, Chandrasekhar Kothuru, Samer Al Hadidi
Methicillin-resistant Staphylococcus aureus (MRSA) commonly causes infection of the skin, soft tissue, bones and heart. MRSA is a rarely reported organism of prostatic abscess (PA). We present a case of an intravenous drug user who presented with dyspareunia, dysuria and dyschezia after a traumatic injury to the rectum. He was diagnosed with PA, which was treated with transurethral resection of the prostate drainage and intravenous antibiotics. MRSA PA carries a low case fatality rate on early diagnosis and treatment with proper antibiotics with or without drainage of the abscess...
March 2018: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29593877/refractory-hyperparathyroidism-with-a-t3-bony-lesion-differential-diagnoses
#5
Daniela W C Chan, Diana Moir, Richard Standish, Mark A Kotowicz
We report a case of severe hyperparathyroidism complicated by osteitis fibrosa cystica in an 83-year-old man post-myocardial infarction. The lesions were evident on magnetic resonance imaging only. A diagnosis of parathyroid carcinoma was considered due to clinical appearance of the parathyroid intraoperatively and the presence of an invasive T3 lesion mimicking metastatic disease. Differentiating parathyroid carcinoma from the benign causes at presentation can be difficult due to overlapping clinical, biochemical, radiological and histological features...
March 2018: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29593876/life-threatening-hemoptysis-case-of-osler-weber-rendu-syndrome
#6
Ricardo Alicea-Guevara, Michael Cruz Caliz, Jose Adorno, Ricardo Fernandez, Kelvin Rivera, Gustavo Gonzalez, Ricardo Alan Hernandez-Castillo, Rosangela Fernandez, Christian Castillo Latorre
Hereditary haemorrhagic telangiectasia (HHT), also known as Osler-Weber-Rendu syndrome, is a rare autosomal dominant vascular disorder. Patients with HHT may present with a wide spectrum of clinical manifestations, some considered to be life-threatening. We present the case of a 53-year-old male who presented with massive haemoptysis. Chest computed tomography scan was remarkable for a large anterior, left lower lobe arteriovenous malformation. The patient underwent a pulmonary angiogram with embolization of a large left lung arteriovenous malformation, which proved to be successful in controlling the bleeding...
March 2018: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29593875/long-term-low-dose-of-clarithromycin-as-a-cause-of-community-acquired-clostridium-difficile-infection-in-a-5-year-old-boy
#7
Hirofumi Namiki, Tadashi Kobayashi
Clostridium difficile is one of the most common causes of antibiotic-associated diarrhoea. Despite C. difficile infection (CDI) has increased in all ages worldwide, episodes of CDI are often misdiagnosed due to the lack of clinical suspicion. Macrolides are also associated with CDI. Additionally, exposure to macrolides in the 12 weeks preceding infection is reported to be a significant risk factor of CDI in a child. We report here a 5-year-old Japanese boy who presented with acute onset of watery diarrhoea...
March 2018: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29593874/statin-induced-rhabdomyolysis-a-complication-of-a-commonly-overlooked-drug-interaction
#8
Saad Ezad, Hooria Cheema, Nicholas Collins
Rhabdomyolysis is a well-documented side effect of statin therapy. This risk is increased with concurrent use of medications that inhibit cytochrome p450-3A4 (CYP3A4), such as macrolide antibiotics. We present the case of a 67-year-old patient who was commenced on clarithromycin on a background of simvastatin therapy, resulting in rhabdomyolysis. This case highlights the need for awareness of common drug interactions associated with statins. It also emphasizes the significance of commencing statins at a lower dose in new patients, and lastly, the importance of early recognition and management of rhabdomyolysis to prevent the development of complications...
March 2018: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29593873/post-transplant-lymphoproliferative-disorder-of-the-bladder-in-a-lung-transplant-recipient
#9
Harpreet Singh Grewal, Charles Lane, Kristin B Highland, Olufemi Akindipe, Marie Budev, Atul C Mehta
Post-transplant lymphoproliferative disorder (PTLD) occurs in ~5% of solid organ and hematopoietic stem cell transplant recipients. We report a unique presentation of PTLD in the bladder of a lung transplant recipient. Our patient was a 62-year-old female who received a bilateral lung transplant for chronic obstructive pulmonary disease. She presented with fever, left-sided flank pain and foul-smelling urine consistent with urosepsis. An abdominal and pelvic computerized tomography revealed an irregular and nodular bladder wall thickening suspicious for urothelial neoplasm...
March 2018: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29576872/pfo-closure-in-high-risk-patient-with-paradoxical-arterial-embolism-deep-vein-thrombosis-pulmonary-embolism-and-factor-v-leiden-genetic-mutation
#10
A Parikh, T P Vacek
Occurrence of paradoxical arterial embolism may cause the first symptoms in patients with a coexisting hypercoagulable state and patent foramen ovale (PFO). This can result in significant morbidity and mortality depending on the location of the embolism. The risks and benefits of closure of small PFOs have not been well elucidated in prior studies. We describe a patient with a history of Factor V Leiden heterozygosity who presented with left arm pain secondary to arterial embolism. The patient was a 51-year-old male who initially presented to the emergency department after awaking from sleep with progressive, severe, burning left arm pain...
March 2018: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29564143/gastric-schwannoma-a-rare-benign-mimic-of-gastrointestinal-stromal-tumor
#11
Tagore Sunkara, Eric Omar Then, Madhavi Reddy, Vinaya Gaduputi
Schwannomas most commonly manifest as acoustic neuromas in the vestibulo-cochlear nerve (CN VIII). These may occur unilaterally as primary tumors, or bilaterally secondary to neurofibromatosis type 2. More rarely, they present in extra-cranial sites, including the gastrointestinal tract. Gastrointestinal schwannomas are believed to arise from Auerbach's plexus in the muscularis propria, and are classified as mesenchymal tumors. Here, we report a rare case of a 49-year-old woman who had surgical resection of a gastric mass which was eventually diagnosed as gastric schwannoma...
March 2018: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29564142/gastric-schwannoma-a-rare-benign-mimic-of-gastrointestinal-stromal-tumour
#12
(no author information available yet)
No abstract text is available yet for this article.
March 2018: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29527312/maintenance-of-renal-function-in-a-patient-with-a-history-of-acute-paroxysmal-nocturnal-hemoglobinuria-associated-kidney-injury
#13
Francesca Re, Ilenia Manfra, Filomena Russo, Caterina Plenteda, Angelica Spolzino, Elena Follini, Maria Gullo, Claudia Romano, Maria Cristina Baroni, Franco Aversa
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, life-threatening blood disorder characterized by intravascular hemolysis, thrombosis and bone marrow failure. Acute kidney injury, including acute renal failure, have been reported in patients with PNH. We report the case of a 36-year-old male patient with PNH who developed acute kidney injury following an infection of undetermined diagnosis. Although hemolysis was initially controlled and renal function stabilized following packed red blood cell transfusion and empirical levofloxacin and prednisone, he later experienced recurrent episodes of hemolysis and hematuria requiring monthly red blood cell support...
March 2018: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29507739/normal-function-of-a-43-year-old-braunwald-cutter-heart-valve
#14
Gian Manuel Jiménez-Rodríguez, Sergio Criales-Vera, Mario Adrian Juárez-Peñaloza, Luis Alonso González-Tapia, Mariana Chaire-Hernández
We present the case of a 72-year-old woman diagnosed with rheumatic fever at the age of 6. In 1972, she was diagnosed with mitral valve insufficiency and mitral valve stenosis, then in 1974, a decision was made to perform mitral valve replacement surgery with a 32-mm Braunwald-Cutter ball cage prosthesis. An echocardiogram performed in 2014 revealed normal biventricular systolic function, mechanical prosthesis in mitral position with maximum speed of 1.9 m/s, maximum gradient of 15 mmHg, mean gradient of 6 mmHg, severe tricuspid valve insufficiency, inferior vena cava measuring 15 mm with more than 50% collapse and pulmonary artery systolic pressure of 40 mmHg...
February 2018: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29507738/fournier-gangrene-in-a-patient-receiving-chemo-radiation-for-rectal-cancer
#15
Maria Pittaka, Chrysanthos Georgiou, Petros Polyviou, Pantelis Kountourakis, Panayiotis Loizou, Ifigenia Constantinou, Demetris Andreopoulos, Vassilios P Vassiliou
We herein present a case of a 24-year-old patient with a cT4N+ rectal cancer who developed Fournier's gangrene (FG) 1 week after the completion of preoperative chemoradiotherapy. The patient was promptly referred to the surgical department where she was treated with antibiotics and repeated surgical debridement. FG is a rare and life-threatening situation that needs to be managed aggressively with no delay. The clinical image above is unique and characteristic of this clinical entity.
February 2018: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29492271/ruptured-hepatic-aneurysm-as-first-presenting-symptom-of-polyarteritis-nodosa
#16
Maria Roberto, Vadim Meytes, Shinban Liu
Polyarteritis nodosa (PAN) is an inflammatory vasculitis that creates regions of stenosis and aneurysm formation. The authors describe a 66-year-old female with hepatic artery rupture as the first presentation of undiagnosed PAN, presenting with abdominal pain followed by hemorrhagic shock. This aneurysm was suture ligated with a successful outcome. A mesenteric arteriogram demonstrated lesions consistent with PAN including aneurysms of the left gastric branches, right and left hepatic arteries, and beaded appearance of the iliac artery...
February 2018: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29492270/chronic-urticaria-and-thyroid-autoimmunity-a-perplexing-association
#17
Subothini Sara Selvendran, Nikhil Aggarwal
Chronic urticaria has long been thought to be associated with autoimmune conditions, in particular autoimmune thyroid disease (AITD). We detail an unusual case of a 49-year-old patient presenting with urticaria distributed on both shins and hands, with no known associated triggers, and subsequently diagnosed with AITD. The urticaria resolved upon treatment of the AITD. We also summarize the currently postulated pathophysiological links between the two diseases. This case highlights that physicians should have a low threshold for investigating autoimmune conditions in cases of chronic urticaria, with particular attention given to AITD...
February 2018: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29492269/mammalian-meat-allergy-following-a-tick-bite-a-case-report
#18
W Landon Jackson
The alpha-gal allergy is an emerging IgE-mediated reaction against the galactose-alpha-1,3-galactose carbohydrate found in mammalian meats. Patients with this condition will develop anaphylactic symptoms 3-6 h after the ingestion of mammalian meat food products such as beef, pork or lamb. The prevalence of this allergy is drastically increasing and severe reactions including anaphylactic shock have been reported, yet many patients experience symptoms for years before a diagnosis is made. We describe the presentation, diagnosis and management of a patient with the alpha-gal allergy in attempt to improve early recognition and management of patients with this condition...
February 2018: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29492268/pericardial-effusion-as-an-atypical-initial-presentation-of-extra-gonadal-nonseminomatous-germ-cell-tumor-a-case-report-and-literature-review
#19
William Paul Skelton, Dhruv Mahtta, Samantha Welniak, Aaron J Franke, Long H Dang
Extra gonadal germ cell tumors have variable clinical presentations and locations. We report a case of an extra-gonadal germ cell tumor in a 26-year-old male who presented with chest pain. Imaging revealed a large pericardial effusion with underlying mass invading the pericardium. Pericardial effusion is an extremely rare initial site of diagnosis or site of metastasis for malignancy. This case illustrates the importance of a thorough history and physical examination, broad differential diagnosis, and to keep in mind serious complications from rare presentations of disease...
February 2018: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29479451/an-unexpected-diagnosis-in-a-patient-with-new-onset-pulmonary-infiltrates-during-adjuvant-therapy-for-breast-cancer
#20
David Aguiar-Bujanda, Laura Ros-Sanjuan, Maria Hernandez-Sosa, Carmen Perera-Romero
The differential diagnosis of new-onset pulmonary infiltrates during adjuvant therapy in a cancer patient is challenging. Opportunistic infections, pulmonary drug-induced toxicity and metastatic dissemination of the underlying cancer are the most common causes. However, although infrequent, the development of a second primary pulmonary neoplasia should be taken into account. We present the clinical case of a breast cancer patient who developed progressive pulmonary infiltrates during adjuvant therapy, who was finally diagnosed as having a second lung neoplasm of unexpected histology...
February 2018: Oxford Medical Case Reports
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