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Oxford Medical Case Reports

Eriko Kashihara, Kohei Fujita, Hiroshi Koyama, Tadashi Mio
Septic pulmonary embolism (SPE) is a rare condition, indicating bacteraemia. We report a rare case of Staphylococcus aureus bacteraemia causing SPE and multiple abscesses in a previously healthy patient. A previously healthy 33-year-old man presented to our hospital with fever and back pain for 3 weeks. Chest contrast-enhanced computed tomography image was suggestive of SPE, and the blood culture showed methicillin-susceptible S. aureus . Additional focus identification revealed pyogenic spondylitis and abscesses in the psoas muscles...
December 2018: Oxford Medical Case Reports
Andy Sing Ong Tang, Yeon Chiat Teh, Chin Yung Chea, Siaw Tze Yeo, Hock Hin Chua
We present a case of disseminated Kaposi's sarcoma with both cutaneous and extracutaneous involvement in an HIV-infected patient with a relatively high CD4 count of 369 cell/mm3 . He developed chronic diarrhea, constitutional symptoms, worsening bilateral pleural effusion with respiratory distress, and progression of skin lesions distributed over his chest and extremities. The temporal relationship between rapid clinical progression and initiation of HAART suggested the possibility of Kaposi's sarcoma-associated immune reconstitution inflammatory syndrome, which eventually resulted in the death of this patient...
December 2018: Oxford Medical Case Reports
Per Sundbom, Anne-Marie Suutari, Karim Abdulhadi, Wojciech Broda, Melinda Csegedi
Myocarditis is mostly caused by viral infections and rarely caused by bacterial pathogens, especially in immunocompetent individuals. Bacterial myocarditis due to Salmonella is rare, especially in countries with improved sanitation that minimize contamination of Salmonella typhi serotypes. We here present a case of a previous healthy 22-year-old male that came to the emergency room with chest pain. His symptoms occurred after a period of profuse diarrhea, fever and hematochezia. Magnetic resonance imaging confirmed the diagnosis of myocarditis...
December 2018: Oxford Medical Case Reports
Siona Growcott, Alexandra Banner, Adam Bray, Serena Hilman
Cabozantinib is a tyrosine kinase inhibitor which is increasingly being used for the treatment of metastatic renal cell cancer. Skin toxicity such as palmar-plantar erythrodysesthesia is not uncommon with such agents. However, bullous skin reactions are not common and we report the case of a patient with metastatic renal cell cancer who experienced such cutaneous toxicity.
December 2018: Oxford Medical Case Reports
Muhammad Y Adeel, John-Ross D Clarke, Safal Shetty, Ashish Arora, Michael G Buscher
We report the case of a 52-year-old gentleman, admitted to the medical intensive care unit with multiple organ system dysfunction due to acute severe pancreatitis. He was found to have severe hypocalcemia, bradycardia and an electrocardiogram (EKG) showing ST-segment elevation in infero-lateral leads. The patient was treated with intravenous calcium gluconate with prompt improvement of heart rate and reversal of EKG changes. Subsequent evaluation for myocardial ischemia was negative. We believe the EKG changes mimicking acute ST-segment elevation myocardial infarction were due to severe hypocalcemia...
December 2018: Oxford Medical Case Reports
M A Waduud, M Giannoudi, M Drozd, C J Malkin, J V Patel, D J A Scott
Subclavian artery stenosis (SAS) resulting in coronary subclavian steal syndrome (CSSS) is a common but under recognized pathology following coronary artery bypass surgery (CABG). Patients with SAS may be asymptomatic due to the sub-clinical diversion of blood flow from the myocardium and retrograde blood flow during catheter angiography in the left internal mammary artery (LIMA) may be the first suggestion of CSSS. The management of SAS, causing CSSS, may rarely require acute assessment and intervention. However, full anatomical assessment of the stenosis morphology may be limited on fluoroscopy...
December 2018: Oxford Medical Case Reports
Chisato Kasuya, Mina Suzuki, Yukako Koda, Hitomi Sato, Katsunori Kashima, Keisuke Honda, Yoshiki Kazama, Katsuhiko Akiyama, Yasuhiro Seki, Yuichiro Yoneoka
A 32-year-old pregnant woman in her 39th week of pregnancy presented at the emergency room complaining of sudden-onset dizziness with gaze disturbance and was admitted to our hospital. Her past medical history included hypertension, diabetes mellitus and infarction in the right medulla oblongata 18 months prior to this event. Magnetic resonance (MR) angiography showed multiple irregular stenosis of the intracranial arterial system. Although MR images revealed no fresh ischemic or hemorrhagic lesions, she was diagnosed with reversible cerebral vasoconstriction syndrome (RVCS) associated with pregnancy...
December 2018: Oxford Medical Case Reports
Ioannis M Stavrakakis, Ioannis I Daskalakis, Emmanouil Panagiotis S Detsis, Chrysanthi A Karagianni, Sofia N Papantonaki, Maria S Katsafarou
Hand compartment syndrome is a rare condition which can result from crush injuries, fractures, burns, intravenous fluid extravasation, etc. Failing to recognize and treat it early leads to significant functional deficits of the hand. Few cases of iatrogenic hand compartment syndrome have been described in the literature so far. We present a case of a hand intravenous (IV) contrast medium extravasation injury in a 72-year-old female patient, during a CT scan. As soon as the swelling of the hand was noticed, elevation of the limb was suggested and ice was applied...
December 2018: Oxford Medical Case Reports
Alexandra Rodrigues, António Jorge Cabral, Anabela Faria, Ana Marques
No abstract text is available yet for this article.
December 2018: Oxford Medical Case Reports
Kosuke Maeda, Jun-Ichi Taniguchi, Kunihiko Matsui
Numb chin syndrome (NCS) is defined as reduced or absent sensation in an area of the chin and lower lip within the distribution of the mental or inferior alveolar nerves. The causes of NCS may be neoplastic, traumatic, dental, toxic, drug-induced, inflammatory, autoimmune or infectious. NCS may be the preliminary symptom of malignancy or recurrence/metastasis in patients with cancer. Therefore, the occurrence of NCS warrants careful examination and monitoring of such patients. This article presents two cases of NCS reported in a patient with prostate cancer and in a patient with Burkitt lymphoma/leukaemia...
December 2018: Oxford Medical Case Reports
Sara Aljarad, Ahmad Alhamid, Ahmad Rami Rahmeh, Abdelaziz Alibraheem, Abdulsamad Wafa, Walid Alachkar, Ziad Aljarad, Ghasan Aziz
Bloom syndrome is a rare autosomal recessive disease, in which BLM gene is mutated, leading to genome instability and proneness to malignancy. It is characterized by short stature, sun-sensitive rash and immunodeficiency. We present a case of bloom syndrome with myelodysplasia complicated by acute myeloid leukaemia. This case has new ophthalmologic manifestations. We confirmed the diagnosis by detection of high rate of sister chromatid exchange. The patient received chemotherapy but did not tolerate it well and developed fungal pneumonia...
December 2018: Oxford Medical Case Reports
Sean P Doyle, Saumya S Gurbani, Alexandra S Ross, Havi Rosen, Charlice Dunn Barrett, Jeffrey J Olson, Hyunsuk Shim, Hui-Kuo Shu, Soma Sengupta
The standard treatment for patients diagnosed with glioblastoma is surgical resection of tumor followed by high dose radiation and chemotherapy with temozolomide. For patients who experience allergic reactions to temozolomide despite desensitization protocols, alternative therapies must be considered. In this report, we present such a patient who then received treatment with an epidermal growth factor receptor inhibitor, erlotinib, concurrent with a tumor-treating field device, Optune. Through this combination of a targeted molecular therapy and the Optune device, the patient has been able to achieve stable disease 9 months after completing radiation...
December 2018: Oxford Medical Case Reports
Michael Hollis, Chibueze Onyemkpa, Tolutope Oyasiji
Adrenal oncocytomas and retroperitoneal schwannomas are two groups of very rare tumors with distinct histologic features. Both tumors are usually incidentally found and are mostly benign. Optimal management is usually with surgical resection. We report a unique case of a 74-year-old woman who was incidentally found to have these two exceptionally rare tumors at the same time. She was successfully managed with surgical resection of the retroperitoneal schwannoma and adrenalectomy for the adrenal oncocytoma and both diagnoses were confirmed with histopathology and immunochemistry...
December 2018: Oxford Medical Case Reports
Shafee Salloum, Ajay Goenka, Adam Mezoff
Beriberi or vitamin B1 deficiency is a rare disease in the developed world and more common in developing countries due to poverty and malnutrition. It usually presents with neurological manifestations (dry beriberi) or cardiovascular signs (wet beriberi). We report a case of dry beriberi in an 11-year-old girl with total colectomy who presented to our hospital with ataxic gait and muscle weakness. Her symptoms started 1 week after she underwent cholecystectomy for her chronic abdominal pain. Nerve conduction study showed sensory demyelinating neuropathy and she had low levels of serum vitamin B1...
November 2018: Oxford Medical Case Reports
Hiroshi Kataoka, Nobuyuki Eura, Takao Kiriyama, Yuto Uchihara, Kazuma Sugie
We describe two patients with Parkinson's disease who presented with accidental hypothermia and review seven patients to delineate the characteristics of hypothermia. All cases of hypothermia occurred in the winter. As clinical symptoms preceding the onset of hypothermia, deterioration of bradykinesia or limb coldness was evident. Most cases of hypothermia were accompanied by impaired consciousness and deterioration of parkinsonian features. After warming the body, the hypothermia improved in a relatively short period...
November 2018: Oxford Medical Case Reports
William Muñoz, Alexandra Lamm, David Poppers, Steven Lamm
Excessive consumption of carbonated drinks contributes to the dietary surplus of carbohydrates, and is a main driver of the obesity epidemic in the USA. From a public health standpoint, it is therefore crucial to develop strategies that enable individuals to regulate this calorie-rich, but nutrient-poor food intake. However, conservative medical approaches to this end have met with limited success. Using a pharmacological strategy to eliminate the effervescent aspect of carbonated drinks, we report significant weight loss in a patient with long-standing obesity...
November 2018: Oxford Medical Case Reports
Eleni Papageorgiou, Sotirios Kalampalikis, Petros Koltsidopoulos, Evangelia Tsironi
No abstract text is available yet for this article.
November 2018: Oxford Medical Case Reports
Takehiro Tozuka, Teppei Sugano, Rintaro Noro, Natsuki Takano, Kakeru Hisakane, Satoshi Takahashi, Toru Tanaka, Takeru Kashiwada, Susumu Takeuchi, Shinobu Kunugi, Yuji Minegishi, Yoshinobu Saito, Kaoru Kubota, Masahiro Seike, Akihiko Gemma
An 82-year-old man with a recurrence of pulmonary pleomorphic carcinoma was treated with pembrolizumab. He achieved partial response after three cycles of pembrolizumab. However, he developed febrile neutropenia. A bone marrow aspiration sample revealed a decrease of mature neutrophils, and anti-neutrophil antibody was detected in blood. Computed tomography scans revealed consolidation in the right lung. Pathological findings in lung biopsy tissue revealed organizing pneumonia. Pembrolizumab-induced agranulocytosis and interstitial lung disease (ILD) were diagnosed...
November 2018: Oxford Medical Case Reports
Tsuneaki Kenzaka, Ken Goda
No abstract text is available yet for this article.
November 2018: Oxford Medical Case Reports
Siow Yun Wong, Samuel Kang Lian Lee, Chaozer Er, Navin Kuthiah
Salmonella typhi and paratyphi infections can manifest as acute abdomen due to intestinal perforations, salpingitis and rarely appendicitis. Non-typhoidal salmonella infection that usually only causes self-limiting gastroenteritis, is rarely associated with appendicitis. We present the case of a 78-year-old gentleman with Salmonella bacteraemia complicated by acute appendicitis. He was treated conservatively due to multiple comorbidities. His condition improved after completion of 2 weeks of antibiotics guided by the blood and stool culture results...
November 2018: Oxford Medical Case Reports
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