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Journal of Oral Biology and Craniofacial Research

Vikas Sandilya, Neelam Noel Andrade, Paul C Mathai, Natarajan Chelappa Balaji
Arch bars are commonly used in maxillofacial surgery but their intraoral presence for an extremely long period is quite uncommon or rare. So when such a patient reports and denies having any complaints all these years, the question that presents is, how is this possible? What kept the patient so long? A review of the existing literature shows, despite being common in trauma care, failure to follow-up has not received the due attention. This study retrospectively reviews the various factors implicated for failure to follow-up and the proposed corrective measures...
May 2018: Journal of Oral Biology and Craniofacial Research
S Nathwani, K Martin, R Bunyan
Focal Dermal Hypoplasia (FDH) or Goltz-Gorlin syndrome is an unusual X-linked dominant syndrome characterised by anomalies of both ectodermal and mesodermal structures. We present a case report on the management of a 58 year old Caucasian male with Focal Dermal Hypoplasia. This report describes an additional clinical manifestation of an intraosseous mandibular lipoma, which has not been previously described in cases of FDH. Intraosseous lipomas in the head and neck region are reported in only seventeen cases in isolation of any associated syndrome...
May 2018: Journal of Oral Biology and Craniofacial Research
Bong-Hae Cho, Dong-Hoon Shin, Yun-Hoa Jung, Hae-Ryoun Park
Burkitt lymphoma, a subtype of non-Hodgkin's lymphoma, is an aggressive neoplasm with three variants that are endemic, sporadic, and immunodeficiency associated. We present an unusual case of sporadic Burkitt lymphoma in a 6-year-old boy who initially presented with hypermobile teeth and no other specific signs or symptoms. On dental radiography, the patient was found to have alveolar bone resorption adjacent to the maxillary first molars, with the appearance of floating teeth. In addition, magnetic resonance imaging (MRI) showed extensive soft tissue masses involving four quadrants of the jaws...
May 2018: Journal of Oral Biology and Craniofacial Research
Mohit K Gunwal, Pratima R Shenoi, Tanvee Paranjape, Sonal Dhote, Ravish Tongya, Magesh Kumar, Sanjay Rastogi
Objectives: To evaluate the fracture resistance and mode of failure of maxillary premolars restorations restored with nanohybrid Composite, ORMOCER and Ceramic Inlays. Materials and method: 100 extracted first maxillary premolar were collected. Samples were divided into five groups. Group I - Intact premolars, Group II -MOD cavities without restorations, Group III - MOD cavities restored with composite restoration, GROUP IV - MOD cavities restored with ORMOCER restoration and GROUP V - MOD cavities restored with ceramic inlays...
May 2018: Journal of Oral Biology and Craniofacial Research
Monika Bansal, Neelam Mittal, Sarita Kumari Yadav, Gayasuddin Khan, Pooja Gupta, Brahmeshwar Mishra, Gopal Nath
Background: This study aimed to formulate and characterize in-situ gel containing levofloxacin and metronidazole to release drugs in controlled manner for treatment of periodontitis. Material and Methods: Medicated in-situ gel with levofloxacin (10% w/v), metronidazole (25% w/v) and vehicle in-situ gel without drugs having poloxamer 407 (20% w/v) and chitosan (0.5%, 1%, 1.5%, 2.0% 2.5% w/v) were prepared and characterized for physicochemical, mechanical properties, stability and in-vitro drug release...
May 2018: Journal of Oral Biology and Craniofacial Research
Harpal Jakhu, Gurveen Gill, Amarjot Singh
Wound healing in human periodontium is a complex process which involves both cell-cell and cell-matrix interactions. Integrins play a major role in regulation of these cell-cell, cell-matrix interaction. Wound healing involves two major events i.e. re-epithelialization and connective tissue repair. In this concise review, we will discuss the role of integrins in these major events as well as their impIications in periodontal wound repair. Integrins are differentially expressed in both of these major events...
May 2018: Journal of Oral Biology and Craniofacial Research
Rajan Gupta, Satwinder Kaur, Parveen Dahiya, Mukesh Kumar
The treatment of periodontitis primarily consists of mechanical debridement carried out by means of thorough scaling and root planing that might sometimes be a painful procedure which requires the administration of some form of local anesthesia. The present study comparatively evaluates the anesthetic effect of three such forms, viz; eutectic mixture of 25 mg/g lignocaine plus 25 mg/g prilocaine (EMLA) and needleless jet anesthesia during SRP. 30 patients with probing depth of 5 mm or more and visual analog scale (VAS) score of ≥30 mm on probing were selected and asked to assess the pain by VAS and verbal rating scale (VRS) during SRP after application of the two agents...
May 2018: Journal of Oral Biology and Craniofacial Research
Aakansha Sharma, Nidhi Agarwal, Ashish Anand, Zohra Jabin
Introduction: Streptococcus mutans is the prime microbe responsible for caries. Mouthwashes represent an effective means for decreasing their count. To ascertain this, three commercially available mouthrinses were evaluated for their antimicrobial activity. Materials and method: Chlorhexidine, Sodium fluoride and Herbal mouth rinse were evaluated for their efficacy against S. mutans in 60 children aged 6-12 years old. Plain water acted as the control group. Results: The values obtained were subjected to statistical analysis...
May 2018: Journal of Oral Biology and Craniofacial Research
Shikha Tewari, Geetanjali Sharma, Sanjay Tewari, Shweta Mittal, Shweta Bansal
Background and objective: Management of combined endodontic-periodontal lesions needs more clinical investigations. The aim of this prospective randomized clinical trial was to evaluate the effect oftime interval between the non-surgical endodontic treatment (ET) and open flap debridement (OFD) on periodontal healing in combined endodontic periodontal lesions with apical communication. Methods: Forty patients were randomly allocated to two treatment protocols. Group 1(immediate periodontal surgery): OFD was performed at 21 days of initiation of ET and SRP, and Group 2(delayed periodontal surgery): OFD was performed after 3 months of initiation of ET and SRP...
May 2018: Journal of Oral Biology and Craniofacial Research
Stuti Gupta, Shivjot Chhina, Sachit Anand Arora
The objective of the study was to conduct a systematic review of the literature so as to evaluate and summarize the diagnostic and prognostic potential of GCF. Included studies were systematically analyzed based on PRISMA (Preferred Reporting Items For Systematic Reviews and Meta Analyses) and studies were identified based on the-PICO (Glossary of evidence based terms 2007): 1)Patients with chronic periodontitis.2)Intervention- NSPT (Non-SurgicalPeriodontal therapy); NSPT + Chemotherapeutics.3)Comparison between treated v/s non treated sites...
May 2018: Journal of Oral Biology and Craniofacial Research
Bhavana Gupta, Shaleen Chandra, Vineet Raj, Vivek Gupta
Background: The nucleolar organizer region (NOR) is by definition part of a chromosome, and nucleolus is a structure containing this chromosomal part and in addition the material which accumulate around the NOR, mostly rRNAs and their precursors as well as specific ribosomal proteins. Argyrophilic Nucleolar organizing region (AgNOR) are silver binding NORs often used to study cell proliferation in various types of tumors. Aim: Quantitative assessment of Argyrophilic Nucleolar organizing region count and its comparison among dentigerous cyst, keratocystic odontogenic tumor and ameloblastoma...
May 2018: Journal of Oral Biology and Craniofacial Research
Neelam Andrade, Neha Aggrawal, Guruprasad Jadhav, Vyankatesh Sahu, Paul C Mathai
Until date conventional radiographs and computed tomography are the preferred diagnostic modalities to monitor the distraction osteogenesis regenerate. But these techniques do not detect the ongoing osteogenic process; moreover they obligate the patient to serial radiation exposure. In addition, anatomic overlap and metal artifacts obscure the virtual findings. In contrast, ultrasound is a noninvasive, efficient and an inexpensive way to evaluate bone healing. This study was conducted to test the efficacy of ultrasound in evaluating bone healing at the mandibular distraction site...
May 2018: Journal of Oral Biology and Craniofacial Research
Sachin Rai, Vidya Rattan, Akshat Gupta, Praveen Kumar
Aims & objective: To evaluate the efficacy of combined intralesional injection of Hyaloronidase and Triamcinolone with third molar removal in early and intermediate stage (Stage II & III) of Oral Submucous Fibrosis (OSMF) for improvement in mouth opening and hypersensitivity to food. Study design: 48 patients in stage II & III OSMF were selected for the study. All the third molars were extracted in each patient followed by 6-8 doses of combined intralesional injection of Hyaloronidase and triamcinolone at 10 days interval targeting the fibrotic bands...
May 2018: Journal of Oral Biology and Craniofacial Research
Ashrafullah, Ramesh Kumar Pandey, Apurva Mishra
Objective: To determine the incidence and pattern of facial fracture in children of age 0-16 years of age. Material & methods: Patients with trauma reporting to department of paediatric and preventive dentistry and department of oral & maxillofacial surgery from January 2011 to December 2011 were selected for the present study. The records of patients treated for maxillofacial injuries were retrospectively retrieved and analyzed for prevalence, pattern, etiology, and management of maxillofacial trauma...
May 2018: Journal of Oral Biology and Craniofacial Research
Manish Bhagania, Wael Youseff, Pushkar Mehra, Ruben Figueroa
Purpose: Retrospective analysis of the efficacy for two commonly used antibiotic regimens in the management of severe odontogenic infections. Patients and Methods: Evaluation of records of patients admitted to the Oral and Maxillofacial Surgery service at Boston University Medical Center from 2009 to 2014 with severe infections of odontogenic origin (SOI). Patients were divided into two groups based on the administered intravenous antibiotic: 1) Group I: Clindamycin only and 2) Group II: Penicillin and Metronidazole...
May 2018: Journal of Oral Biology and Craniofacial Research
Arun Paul S, Sibu Simon S, Saurabh Kumar, Rabin K Chacko
Background: Patients perception of treatment outcomes are invaluable assessment tools and are effective indicators for future prognosis. Various tools of measurement have been used to assess the same. The oral health impact profile questionnaire (OHIP 14) has been effectively used to evaluate the oral health-related quality of life (OHRQoL) with regards to individual perceptions. This study was conducted to assess OHRQoL in patients who have had dental implants to replace missing teeth in the Department of Dental Surgery, Unit 1, Christian Medical College and Hospital, Vellore, TN, India by using the OHIP 14 questionnaire...
May 2018: Journal of Oral Biology and Craniofacial Research
Divya Mehrotra
No abstract text is available yet for this article.
May 2018: Journal of Oral Biology and Craniofacial Research
Rohit Khanna, Kapila Kumar, Raja Roy
The diagnosis and confirmation of oral SCC (squamous cell carcinoma) is still dependent on histopathology report in spite of development of radiological investigations. It is, thus important to understand the underlying molecular mechanisms and how the alterations in metabolic pathways effect the tumor development and progression. The simultaneous and comprehensive information about the presence and absence of small molecule metabolites and their relative concentrations has been provided by 1 H HR-MAS NMR spectroscopy on tissue specimens...
January 2018: Journal of Oral Biology and Craniofacial Research
Subhashree Priyadarsini, Sumit Mukherjee, Monalisa Mishra
Nanotechnology is widely used in our day to day life including its use in medicine. Using nanotechnology, it is easy to analyze and manipulate atoms, chemical bonds and molecules present between various compounds. Nanotechnology is used in the dental field as nano dentistry. While choosing the nanoparticle for the use in the field of nano dentistry its chemical, physical, along with the biological aspect of nanostructures are taken into account. Often various atoms or molecules are added to form the functional structure...
January 2018: Journal of Oral Biology and Craniofacial Research
Vanessa Ávila Sarmento Silveira, Renata Falchete do Prado, Yasmin Rodarte Carvalho, Horácio Faig-Leite
Background: The host's answer has an important role in periodontal disease, and the mast cells have a prime role. Such cells seem to be influenced by estrogen deficiency. The objective was to evaluate the mast cells and the expression of metalloproteinase(MMP)-9 in periodontal disease induced in ovariectomized rats. Methods: For that purpose, 36 rats were used; 18 ovariectomized (OVX) and another 18 Sham-operated (SHAM). After 60 days the periodontal disease was induced by a ligature around the first lower right molars (group P)...
January 2018: Journal of Oral Biology and Craniofacial Research
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