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Journal of Pharmacopuncture

Yean Chun Loh, Chu Shan Tan, Mun Fei Yam, Chuan Wei Oo, Wan Maznah Wan Omar
Objectives: There is an increasing number of complex diseases that are progressively more difficult to be controlled using the conventional "single compound, single target" approach as demonstrated in our current modern drug development. TCM might be the new cornerstone of treatment alternative when the current treatment option is no longer as effective or that we have exhausted it as an option. Orthogonal stimulus-response compatibility group study is one of the most frequently employed formulas to produce optimal herbal combination for treatment of multi-syndromic diseases...
September 2018: Journal of Pharmacopuncture
Bo-Young Jung, Kyeong Han Kim, Song-Yi Kim, Hyun-Kyung Sung, Jeong-Su Park, Ho-Yeon Go, Jang-Kyung Park
Objectives: The study was to survey use of electronic medical records in subjects of Korean medicine doctors working for Korean medicine organizations and to contemplate ways to develop utilization of electronic medical records. Methods: On August 2017, it conducted online self-reported survey on subjects of Korean medicine doctors at Korean hospitals and clinics who agreed to participate in the study. A total 40 doctors in hospital and 279 doctors in clinic were included...
September 2018: Journal of Pharmacopuncture
Zeinab Moshfeghy, Khadegeh Asadi, Marzieh Akbarzadeh, Atefeh Zare, Tahereh Poordast, Masoumeh Emamghoreishi, Fatemeh S Najib, Mehrab Sayadi
Objectives: Vaginal Candidiasis with an approximate prevalence of 30% is the second cause of vaginal infections. Antifungal azole is the first treatment for Vaginal Candidiasis ; however, some side effects have been reported for this chemical medicine. Based on the antifungal activity of Inner Stratum of Quercus Brantii ( Q. Brantii ), the aim of our study was to compare the effects of vaginal douche of Q. Brantii extract and clotrimazole on vaginal candidiasis symptoms before and after the treatments, in women...
September 2018: Journal of Pharmacopuncture
Khadijeh Jamialahmadi, Sofia Salari, Nafiseh Sadat Alamolhodaei, Amir Avan, Leila Gholami, Gholamreza Karimi
Objectives: Auraptene, a natural citrus coumarin, found in plants of Rutaceae and Apiaceae families. In this study, we investigated the effects of auraptene on tumor migration, invasion and matrix metalloproteinase (MMP)-2 and -9 enzymes activity. Methods: The effects of auraptene on the viability of A2780 and Hela cell lines was evaluated by MTT assay. Wound healing migration assay and Boyden chamber assay were determined the effect of auraptene on migration and cell invasion, respectively...
September 2018: Journal of Pharmacopuncture
Kobra Shirani, Hassan Badie Bostan, Ashkan Baroti, Mohammad Hassanzadeh, Zahra Khashyarmanesh, Hamideh Moalemzadeh Haghighi, Gholamreza Karimi
Objectives: Ma-al-shaeer is a popular beverage in Islamic countries. The aim of this study was to determine the concentrations of methanol and ethanol in most consumed brands of Ma-al-shaeer in Iran. Methods: Eighty-one Ma-al-shaeer samples which commonly used in Iran were provided. Methanol and ethanol contents were determined by gas chromatography with flame ionization detector. Results: The mean methanol concentrations in Iranian and foreign brands was 129...
September 2018: Journal of Pharmacopuncture
Maryam Mahmoudabady, Faezeh Sadat Talebian, Narges Amel Zabihi, Seyed Abdolrahim Rezaee, Saeed Niazmand
Objectives: Myocardial reperfusion is the only logical cure for ischemic heart disease. However, ischemic-reperfusion (I/R) injury is one of the underlying factors facilitating and accelerating the apoptosis in the myocardium. This study set to investigate the impact of Teucrium polium (TP) hydro-alcoholic extract on I/R induced apoptosis in the isolated rat heart. Methods: Isolated rat hearts were classified into six groups. The control samples were subjected to 80 min of perfusion with Krebs-Henseleit bicarbonate (KHB) buffer; in control-ischemia group, after primary perfusion (20 min) the hearts were exposed to global ischemia (20 min) and reperfusion (40 min)...
September 2018: Journal of Pharmacopuncture
Seungah Jun, Jung Hee Lee, Han Mi Gong, Seong Hun Choi, Min Hwang Bo, Mi Suk Kang, Geon-Mok Lee, Hyun-Jong Lee, Jae Soo Kim
Objectives: We investigated the efficacy and safety of miniscalpel acupuncture (MA) for knee osteoarthritis (KOA) in an assessor-blinded randomized controlled pilot trial; this would provide information for a large-scale randomized controlled trial. Methods: Participants (n = 24) were recruited and randomly allocated to the MA group (experimental) or acupuncture group (control). The MA group received treatment once a week for 3 weeks (total of 3 treatments), while the acupuncture group received treatment two times per week for 3 weeks (total of 6 treatments)...
September 2018: Journal of Pharmacopuncture
Azin Niazi, Vafa Baradaran Rahimi, Sina Soheili-Far, Nafiseh Askari, Pouria Rahmanian-Devin, Zahra Sanei-Far, Amirhossein Sahebkar, Hassan Rakhshandeh, Vahid Reza Askari
Averagely 80% to 90% of breastfeeding women experience the nipple pain and fissures. The important factor for successful breastfeeding is to treat this problem. This study has done as a review with the aim of analysis of the clinical trials in the field of the prevention and treatment of the nipple fissures and pain due to the importance of breastfeeding. For this purpose, the key words of sore, nipples, fissure, trauma, wound, prevention, treatment, therapeutics, therapy, clinical trial, breastfeeding and their Persian synonyms and all of their possible combinations were searched in the national databases: SID and Iran Medex and Magiran, and in the international databases: PubMed, Scopus, Medline, Science direct by May 2017...
September 2018: Journal of Pharmacopuncture
F Bosco, S Cidin, F Maceri, M Ghilli, M Roncella, L De Simone
This study investigates the effect of a combination of homeopathic medicine and electro-acupuncture in two patients with breast cancer and severe liver disease who could not receive standard anaesthesia therapy due to liver problems. Specifically, measurable and quantifiable parameters were used to evaluate whether an integrated approach-consisting of electro-acupuncture and a homeopathic medicine diluted above Avogadro's limit (that is, above a potency of 12CH) during the pre-surgical, surgical and post-surgical phases--can improve general well-being of a patient undergoing breast cancer surgery...
June 2018: Journal of Pharmacopuncture
Muhack Yang, Jongwon Jang, Eunhye Cha, Byungsoo Ahn, Younghee Bang, Beomyong Song, Jiyong Shin, Chankeun Ahn, Deokho Kim, Sungchul Kim
Objective: The purpose of this study was to investigate the clinical effects of BU pharmacopuncture therapy consisting of bear's gall(fel ursi) and ox bezoar(bovis calculus) on acute lumbar sprain. Methods: 12 patients diagnosed as acute lumbar sprain in 6 designated local Korean medicine clinics from October 2017 to February 2018 were treated by BU pharmacopuncture. Several acupoints in abdomen and lumbar region were selected by clinicians at their own discretion...
June 2018: Journal of Pharmacopuncture
Ui Joung Youn, Bon-Seok Gu, Kyung Hee Kim, Chulgyu Ha, In Chan Jung
Contents of compounds in Rehmanniae Radix change depending on the number of steaming and drying and the drying method. In this study, as an impregnation method for dried Rehmanniae Radix, takju impregnation and cheongju impregnation were carried out and steaming and drying were repeated for 9 times. The changes of 5-HMF and catalpol contents were analyzed according to the number of repetition times to investigate which stage of steaming and drying is preferable. Also, total nitrogen, crude fat, ash, and crude fiber were measured to analyze changes in general components...
June 2018: Journal of Pharmacopuncture
Sunju Park, Hae-Mo Park, Seung-Ho Sun
Objective: This study is to evaluate both the single-dose intravenous injection toxicity and the approximate lethal dose of Water-soluble Danggui Pharmacopuncture (WDP) in Sprague-Dawley (SD) rats. Methods: Toxicity experiments were conducted at Good Laboratory Practice (GLP) laboratory in Biotoxtech Co., according to the regulations of GLP. WDP injection of dose 0.125, 0.25, and 0.5 mL/animal were experimental groups and normal saline injection group was control group...
June 2018: Journal of Pharmacopuncture
Kyeong Han Kim, Jong Uk Kim, Bo Hyun Kim, Jin Hyeon Shin, Seong Jin Hong, Sang Ryong Lee, Tae-Han Yook
Objective: DIt is need to evaluate he changes of the bio-signals through the hot-cold stimulation in the CV4. Methods: The 30 healthy participants were enrolled and randomly allocated, to one of three groups(10 participants for each group): the hot stone therapy(HST) group, or the cold stone therapy(CST) group or no treatment group(NT). All the participants took a rest for 10 minutes for stability before the test. And additional 10 minute rest after measurements of skin test and sEMG...
June 2018: Journal of Pharmacopuncture
Gholamreza Karimi, Samed Hassanzadeh-Josan, Bahram Memar, Seyed-Alireza Esmaeili, Bamdad Riahi-Zanjani
Silymarin is a flavonoid complex extracted from the Silybum marianum plant with a wide range of pharmacological and biochemical effects. In the present study, the immunomodulatory effects of silymarin were investigated in BALB/c mice. Silymarin was administered daily by intraperitoneal injection at doses of 50, 100 and 150 mg/kg for 14 consecutive days. Following the exposure, host hematological parameters, spleen cellularity and histopathological examination, as well as delayed-type hypersensitivity (DTH) responses, hemagglutination titers (HA), splenocyte cytokine production and lymphocyte proliferation assay were studied in all of the test groups of animals...
June 2018: Journal of Pharmacopuncture
Mohammad Reza Safari, Omid Azizi, Somayeh Sadat Heidary, Nejat Kheiripour, Alireza Pouyandeh Ravan
Objective: Diabetes mellitus (DM) is the most common metabolic disorder that defined by chronic hyperglycemia for the deficiency in insulin secretion or resistance. Hyperglycemia could induce non-enzymatic glycation of proteins. It has been suggested that some traditional plants can improve blood glucose and inhibit glycation process. This work evaluates and compares the anti-glycation activities of four Iranian plant extracts in vitro. Methods: The methanolic extract of "Fumaria officinalis, Stachys lavandulifolia, Salvia hydrangea and Rosa Damascene" was prepared in three different concentrations...
June 2018: Journal of Pharmacopuncture
Hassan Abolghasemi, Yunes Panahi, Minoo Ahmadinejad, Gholamreza Toogeh, Mehran Karimi, Aziz Eghbali, Nargess Bigom Mirbehbahani, Bighan Keikhaei Dehdezi, Zahra Badiee, Hamid Hoorfar, Peyman Eshghi, Nader Maghsoudi, Amirhossein Sahebkar, Mohammad Gholami-Fesharaki
Objective: This study compared the safety and efficacy of Safacto® versus xyntha® in patients with severe hemophilia A. Methods: Thirty-three male patients with severe hemophilia A were randomly divided into two groups. Seventeen patients received Safacto® and 16 patients received Xyntha® for four consecutive times. The dosage of FVIII was 40-50 IU/kg for each injection. Plasma level of FVIII activity was evaluated before every injection, 15 minutes after the injection and one month after the start of the trial...
June 2018: Journal of Pharmacopuncture
Samane Arefani, Seyyed Mohammad Mohseni Mehran, Hassan Moladoust, Mohammad Reza Norasfard, Ahmad Ghorbani, Mahmood Abedinzade
Objective: Diseases of the respiratory system are one of the main causes of death and include situation such as chronic obstructive pulmonary disease, pneumonia or asthma. Medicinal plants have beneficial effects on multiple diseases include respiratory disorders like asthma and bronchitis. The aim of this study was to evaluate the effects of U. dioica and L. Album on tracheal smooth muscle contraction. Material and methods: Hydroalcoholic extracts of L. Album and U...
June 2018: Journal of Pharmacopuncture
Alireza Timcheh Hariri, Seyed Adel Moallem, Mahmoud Mahmoudi, Bahram Memar, Bibi Marjan Razavi, Hossein Hosseinzadeh
Objective: In this study, the effects of saffron stigma against subacute diazinon (DZN) toxicity on enzymes levels, biochemical, hematological, histopathological and genotoxicity indices were studied in rats. Methods: Vitamin E (200 IU/kg) and the aqueous extract of saffron (50, 100 and 200 mg/kg) were injected intraperitoneally three times per week alone or with DZN (20 mg/kg/day, orally) for 4 weeks. The hematological and biochemical parameters were evaluated at the end of 4 weeks...
June 2018: Journal of Pharmacopuncture
Yong Ju Kim
Objective: The aim of this study is to optimize the extraction of beneficial substance from Cudrania tricuspidata leaves grown at Jirisan Mountain in South Korea by three different solvents depending on extraction time and at different temperature. Methods: The total phenolic contents were determined by the method reported by Sánchez-Moreno et al. The total flavonoid contents were analyzed by Slinkard and Singleton. The DPPH radical scavenging activity was determined according to the method reported by Blois...
June 2018: Journal of Pharmacopuncture
Najmeh Asrari, Rezvan Yazdian-Robati, Khalil Abnous, BiBi Marjan Razavi, Mrazieh Rashednia, Faezeh Vahdati Hasani, Hossein Hosseinzadeh
Objective: The role of BDNF (brain-derived neurotrophic factor), CREB (cAMP response element binding) and VGF neuropeptide has been proved in antidepressant activity of long term saffron administration in the rat hippocampus. In this study we evaluated the role of these proteins in antidepressant activity of saffron in long term administration in the rat cerebellum. Methods: Saffron aqueous extract (40 and 80 mg/kg/day) and imipramine (10 mg/kg/day) were administered intraperitoneally for 21 days to rats...
March 2018: Journal of Pharmacopuncture
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