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Journal of Pharmacopuncture

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https://www.readbyqxmd.com/read/28392964/the-use-of-korean-medicine-to-treat-patients-with-spinobulbar-muscular-atrophy-kennedy-s-disease-a-case-study
#1
Seongjin Lee, Eunhye Cha, Jongcheol Lee, Jongdeok Lee, Inja Song, Sungchul Kim
OBJECTIVES: Studies involving patients with spinobulbar muscular atrophy (SBMA), which is often referred to as Kennedy's disease, similar to those involving patients with progressive muscular disease (PMD), are rare. This paper reports a case study involving the use of Korean medicine to treat a patient with SBMA. METHODS: We treated a patient with SBMA with unique symptoms by using various kinds of pharmacopuncture and herbal medicines for about two and a half years...
March 2017: Journal of Pharmacopuncture
https://www.readbyqxmd.com/read/28392963/treatment-with-rutin-a-therapeutic-strategy-for-neutrophil-mediated-inflammatory-and-autoimmune-diseases-anti-inflammatory-effects-of-rutin-on-neutrophils
#2
Bahareh Abd Nikfarjam, Mohtaram Adineh, Farid Hajiali, Marjan Nassiri-Asl
OBJECTIVES: Neutrophils represent the front line of human defense against infections. Immediately after stimulation, neutrophilic enzymes are activated and produce toxic mediators such as pro-inflammatory cytokines, nitric oxide (NO) and myeloperoxidase (MPO). These mediators can be toxic not only to infectious agents but also to host tissues. Because flavonoids exhibit antioxidant and anti-inflammatory effects, they are subjects of interest for pharmacological modulation of inflammation...
March 2017: Journal of Pharmacopuncture
https://www.readbyqxmd.com/read/28392962/anti-diabetic-effects-of-an-ethanol-extract-of-cassia-abbreviata-stem-bark-on-diabetic-rats-and-possible-mechanism-of-its-action-anti-diabetic-properties-of-cassia-abbreviata
#3
Keagile Bati, Tebogo Elvis Kwape, Padmaja Chaturvedi
OBJECTIVES: This study aimed to evaluate the hypoglycemic effects of an ethanol extract of Cassia abbreviata (ECA) bark and the possible mechanisms of its action in diabetic albino rats. METHODS: ECA was prepared by soaking the powdered plant material in 70% ethanol. It was filtered and made solvent-free by evaporation on a rotary evaporator. Type 2 diabetes was induced in albino rats by injecting 35 mg/kg body weight (bw) of streptozotocin after having fed the rats a high-fat diet for 2 weeks...
March 2017: Journal of Pharmacopuncture
https://www.readbyqxmd.com/read/28392961/preparation-and-characterization-of-suvarna-bhasma-parada-marit
#4
Kapil Thakur, Ramacharya Gudi, Mahesh Vahalia, Shekhar Shitut, Shailesh Nadkarni
OBJECTIVES: The goal of this study was to characterize Suvarna Bhasma Parada Marit by using the Ayurvedic test parameters, physico-chemical tests, and various instrumentation techniques. METHODS: Suvarna Bhasma, an Ayurvedic formulation manufactured as per Bharat Bhaishajya Ratnakar 5/8357 (BBR), has been studied using various instrumentation techniques: X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDAX), laser particle size distribution (PSD) analysis, fourier transform infrared spectroscopy (FT-IR), and atomic absorption spectroscopy (AAS), and physico-chemical parameters, such as the loss on drying (LOD), loss on ignition (LOI), and acid insoluble Ash (AIA) were determined...
March 2017: Journal of Pharmacopuncture
https://www.readbyqxmd.com/read/28392960/anti-aging-effect-of-nigella-sativa-fixed-oil-on-d-galactose-induced-aging-in-mice
#5
Mahdieh Jafari Shahroudi, Soghra Mehri, Hossein Hosseinzadeh
OBJECTIVES: Aging is an unconscious and gradual process that can lead to changes in biological systems. Induction of oxidative stress and apoptosis, hepatotoxicity and neurotoxicity are involved in the aging process. Regarding the antioxidant property of black seed oil, the aim of this study was to evaluate the anti-aging effect of Nigella sativa (N. sativa) oil on d-galactose-induced aging in mice. METHODS: For induction of aging, D-galactose (500 mg/kg, subcoutaneously SC) was administrated to male mice for 42 days...
March 2017: Journal of Pharmacopuncture
https://www.readbyqxmd.com/read/28392959/restricted-blood-flow-exercise-in-sedentary-overweight-african-american-females-may-increase-muscle-strength-and-decrease-endothelial-function-and-vascular-autoregulation
#6
Vernon Bond, Bryan Heath Curry, Krishna Kumar, Sudhakar Pemminati, Vasavi Rakesh Gorantla, Kishan Kadur, Richard Mark Millis
OBJECTIVES: Exercise with partially restricted blood flow is a low-load, low-intensity resistance training regimen which may have the potential to increase muscle strength in the obese, elderly and frail who are unable to do high-load training. Restricted blood flow exercise has also been shown to affect blood vessel function variably and can, therefore, contribute to blood vessel dysfunction. This pilot study tests the hypothesis that unilateral resistance training of the leg extensors with partially restricted blood flow increases muscle strength and decreases vascular autoregulation...
March 2017: Journal of Pharmacopuncture
https://www.readbyqxmd.com/read/28392958/methanolic-extract-of-plumbago-zeylanica-a-remarkable-antibacterial-agent-against-many-human-and-agricultural-pathogens
#7
Mukesh Kumar Singh, Ajit Pandey, Hemant Sawarkar, Anshita Gupta, Bina Gidwani, Hemant Dhongade, Dulal Krishna Tripathi
OBJECTIVES: The current investigation was carried out to determine the cytotoxic and the antimicrobial activities of methanolic extracts of Plumbago zeylanica. METHODS: The stems, leaves, and whole plants were air dried and extracted with methanol by using a Soxhlet extractor for 72 hours at 55 - 60°C. The antimicrobial activities were determined from the zones of inhibition, which were measured by using the agar well diffusion method, and the cytotoxicity assays were performed using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay method...
March 2017: Journal of Pharmacopuncture
https://www.readbyqxmd.com/read/28392957/boswellic-acid-improves-cognitive-function-in-a-rat-model-through-its-antioxidant-activity-neuroprotective-effect-of-boswellic-acid
#8
Saeedeh Ebrahimpour, Mehdi Fazeli, Soghra Mehri, Mahnaz Taherianfard, Hossein Hosseinzadeh
OBJECTIVES: Boswellic acid (BA), a compound isolated from the gum-resin of Boswellia carterii, is a pentacyclic terpenoid that is active against many inflammatory diseases, including cancer, arthritis, chronic colitis, ulcerative colitis, Crohn's disease, and memory impairment, but the mechanism is poorly understood. This study investigated the effects of boswellic acid on spatial learning and memory impairment induced by trimethyltin (TMT) in Wistar rats. METHODS: Forty male Wistar rats were randomly divided into 5 groups: Normal group, TMT-administrated rats (8...
March 2017: Journal of Pharmacopuncture
https://www.readbyqxmd.com/read/28392956/effects-of-herbal-medicine-gan-mai-da-zao-decoction-on-several-types-of-neuropsychiatric-disorders-in-an-animal-model-a-systematic-review-herbal-medicine-for-animal-studies-of-neuropsychiatric-diseases
#9
REVIEW
Su Ran Kim, Hye Won Lee, Ji Hee Jun, Byoung-Seob Ko
OBJECTIVES: Gan Mai Da Zao (GMDZ) decoction is widely used for the treatment of various diseases of the internal organ and of the central nervous system. The aim of this study is to investigate the effects of GMDZ decoction on neuropsychiatric disorders in an animal model. METHODS: We searched seven databases for randomized animal studies published until April 2015: Pubmed, four Korean databases (DBpia, Oriental Medicine Advanced Searching Integrated System, Korean Studies Information Service System, and Research Information Sharing Service), and one Chinese database (China National Knowledge Infrastructure)...
March 2017: Journal of Pharmacopuncture
https://www.readbyqxmd.com/read/28127503/embryonic-zebrafish-model-a-well-established-method-for-rapidly-assessing-the-toxicity-of-homeopathic-drugs-toxicity-evaluation-of-homeopathic-drugs-using-zebrafish-embryo-model
#10
Himanshu R Gupta, Yogesh Patil, Dipty Singh, Mansee Thakur
OBJECTIVES: Advancements in nanotechnology have led to nanoparticle (NP) use in various fields of medicine. Although the potential of NPs is promising, the lack of documented evidence on the toxicological effects of NPs is concerning. A few studies have documented that homeopathy uses NPs. Unfortunately, very few sound scientific studies have explored the toxic effects of homeopathic drugs. Citing this lack of high-quality scientific evidence, regulatory agencies have been reluctant to endorse homeopathic treatment as an alternative or adjunct treatment...
December 2016: Journal of Pharmacopuncture
https://www.readbyqxmd.com/read/28116222/should-cam-and-cam-training-programs-be-included-in-the-curriculum-of-schools-that-provide-health-education
#11
REVIEW
Ozgur Onal, Deniz Say Sahin, Betul Battaloglu Inanc
OBJECTIVES: This study aimed to determine the knowledge levels and attitudes of School of Health and Vocational School of Health students toward complementary and alternative medicine (CAM). METHODS: Three hundred thirty-three (333) students studying at the Mehmet Akif Ersoy University School of Health and the Golhisar Vocational School of Health in Burdur, Turkey, were included in the study. Research data were collected by using a survey method based on the expressed opinions of the participants...
December 2016: Journal of Pharmacopuncture
https://www.readbyqxmd.com/read/28097045/homeopathy-a-safe-much-less-expensive-non-invasive-viable-alternative-for-the-treatment-of-patients-suffering-from-loss-of-lumbar-lordosis
#12
Saiful Haque, Debarsi Das, Saugato Bhattacharya, Tathagato Sarkar, Anisur Rahman Khuda-Bukhsh
OBJECTIVES: Loss of lumbar lordosis causing pain and curvature of the vertebral skeleton to one side is a relatively uncommon disease. To our knowledge, successful treatment of loss of lumbar lordosis with any potentized homeopathic drug diluted above Avogadro's limit (that is, above a potency of 12C) has not been documented so far. In this communication, we intend to document a relatively rare case of loss of lumbar lordosis with osteophytic lippings, disc desiccation, and protrusion, causing a narrowing of secondary spinal canal and a bilateral neural foramina, leading to vertebral column curvature with acute pain in an adolescent boy...
December 2016: Journal of Pharmacopuncture
https://www.readbyqxmd.com/read/28097044/study-on-the-single-dose-toxicity-of-shineumhur-pharmacopuncture-injected-into-the-muscles-of-rats
#13
Hohyun Jeong, Eunhye Cha, Jongcheol Lee, Seongjin Lee, Manyong Park, Dongwoung Kim, Bongkeun Song, Jongdeok Lee, Sungchul Kim
OBJECTIVES: This study was carried out to analyze the single dose toxicity of ShinEumHur (SEH) pharmacopuncture injected into the muscles of Sprague-Dawley rats. METHODS: The SEH pharmacopuncture was made in a clean room at the Korean Pharmacopuncture Institute (K-GMP). After the mixing process with sterile distilled water had been completed, the pH was controlled to between 7.0 and 7.5. All experiments were conducted at Biotoxtech, an institution authorized to perform non-clinical studies under the Good Laboratory Practice (GLP) regulations...
December 2016: Journal of Pharmacopuncture
https://www.readbyqxmd.com/read/28097043/single-dose-intramuscular-toxicity-of-mahwangcheonoh-pharmacopuncture-in-a-rat-model-toxicity-of-mahwangcheonoh-pharmacopuncture-in-sd-rats
#14
Heejin Sung, Eunyong Lee
OBJECTIVES: This study was conducted to analyze the single-dose toxicity and the safety of Mahwangcheonoh pharmacopuncture extracts. METHODS: Six-week-old Sprague-Dawley rats were used for this study. Doses of Mahwangcheonoh pharmacopuncture extracts were set at 0.25 mL (low-dose), 0.5 mL (medium-dose) and 1.0 mL (high-dose) for the test groups. A dose of 1.0 mL of normal saline solution was set for the control group. During 14 days, general symptoms, mortalities, and changes in hematology, blood biochemistry and histopathology of all rats were observed...
December 2016: Journal of Pharmacopuncture
https://www.readbyqxmd.com/read/28097042/the-relaxant-activity-of-safranal-in-isolated-rat-aortas-is-mediated-predominantly-via-an-endothelium-independent-mechanism-vasodilatory-mechanism-of-safranal
#15
Bibi Marjan Razavi, Mojtaba Alipoor Amanloo, Mohsen Imenshahidi, Hossein Hosseinzadeh
OBJECTIVES: Safranal is a pharmacologically active component of saffron and is responsible for the unique aroma of saffron. The hypotensive effect of safranal has been shown in previous studies. This study evaluates the mechanism for the vasodilatory effects induced by safranal on isolated rat aortas. METHODS: To study the vasodilatory effects of safranal (0.2, 0.4 and 0.8 mM), we contracted isolated rat thoracic aorta rings by using 10(-6)-M phenylephrine (PE) or 80-mM KCl...
December 2016: Journal of Pharmacopuncture
https://www.readbyqxmd.com/read/28097041/effect-of-catechins-green-tea-extract-and-methylxanthines-in-combination-with-gentamicin-against-staphylococcus-aureus-and-pseudomonas-aeruginosa-combination-therapy-against-resistant-bacteria
#16
Bibi Sedigheh Fazly Bazzaz, Sahar Sarabandi, Bahman Khameneh, Hossein Hosseinzadeh
OBJECTIVES: Bacterial resistant infections have become a global health challenge and threaten the society's health. Thus, an urgent need exists to find ways to combat resistant pathogens. One promising approach to overcoming bacterial resistance is the use of herbal products. Green tea catechins, the major green tea polyphenols, show antimicrobial activity against resistant pathogens. The present study aimed to investigate the effect of catechins, green tea extract, and methylxanthines in combination with gentamicin against standard and clinical isolates of Staphylococcus aureus (S...
December 2016: Journal of Pharmacopuncture
https://www.readbyqxmd.com/read/28097040/effects-of-inhalable-microparticles-of-seonpyejeongcheon-tang-in-an-asthma-mouse-model-effects-of-microparticles-of-sjt
#17
Won-Kyung Yang, Chul-Hwa Lee, Min-Hee Kim, Seung-Hyeong Kim, Hae-Yoon Choi, Yoon Yeo, Yang-Chun Park
OBJECTIVES: Allergic asthma generally presents with symptoms of wheezing, coughing, breathlessness, and airway inflammation. Seonpyejeongcheon-tang (SJT) consists of 12 herbs. It originated from Jeongcheon-tang (JT), also known as Ding-chuan-tang, composed of 7 herbs, in She-sheng-zhong-miao-fang. This study aimed to evaluate the effects of local delivery of SJT via inhalable microparticles in an asthma mouse model. METHODS: Microparticles containing SJT were produced by spray-drying with leucine as an excipient...
December 2016: Journal of Pharmacopuncture
https://www.readbyqxmd.com/read/28097039/the-concept-of-wind-in-traditional-chinese-medicine
#18
REVIEW
Mehrab Dashtdar, Mohammad Reza Dashtdar, Babak Dashtdar, Karima Kardi, Mohammad Khabaz Shirazi
The use of folk medicine has been widely embraced in many developed countries under the name of traditional, complementary and alternative medicine (TCAM) and is now becoming the mainstream in the UK and the rest of Europe, as well as in North America and Australia. Diversity, easy accessibility, broad continuity, relatively low cost, base levels of technological inputs, fewer side effects, and growing economic importance are some of the positive features of folk medicine. In this framework, a critical need exists to introduce the practice of folk medicine into public healthcare if the goal of reformed access to healthcare facilities is to be achieved...
December 2016: Journal of Pharmacopuncture
https://www.readbyqxmd.com/read/28070450/the-current-status-of-new-antidiabetic-drugs
#19
Sudhakar Pemminati, Richard Mark Millis, Ashwin Kamath, Ashok Kudgi Shenoy, Vasavi Rakesh Gorantla
No abstract text is available yet for this article.
December 2016: Journal of Pharmacopuncture
https://www.readbyqxmd.com/read/27695636/combination-therapy-of-gefitinib-and-korean-herbal-medicines-could-be-a-beneficial-option-for-patients-with-non-small-cell-lung-cancer
#20
Kangwook Lee, Yoon-Sik Kim, Chang-Gue Son, Jung-Hyo Cho, Hwa-Seung Yoo, Jonghoon Lee, Juyoung Ryu, Namhun Lee
ABSTRACT: HASH(0x40a13f8) ABSTRACT: Lung cancer has a high mortality rate and is often diagnosed at the metastatic stage. Gefitinib is a targeted molecular therapeutic drug used to treat patients with non-small-cell lung cancer (NSCLC). Korean herbal medicines may also have therapeutic efficacy against lung cancer, reduce the side effects associated with chemotherapy, and improve patient quality of life (QOL). This case report describes the effects of a Korean herbal medicine regimen combined with gefitinib in a patient with NSCLC and bone metastasis...
September 2016: Journal of Pharmacopuncture
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