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Journal of International Advanced Otology

Enes Yiğit, Deniz Tuna Edizer, Yusuf Muhammed Durna, Mengühan Araz Altay, Özgür Yiğit
OBJECTIVES: To evaluate the satisfaction with life among mothers of pediatric cochlear implant candidates regarding implant surgery and sociodemographic factors. MATERIALS AND METHODS: Mothers of 160 pediatric patients with profound sensorineural hearing loss who underwent unilateral cochlear implant surgery were included. A questionnaire form with items on sociodemographic-familial characteristics and Satisfaction with Life Scale (SWLS) was employed via face-to-face interview method before and 12 months after the implant surgery...
August 3, 2018: Journal of International Advanced Otology
Matthew Yung, Adrian James, Paul Merkus, John Philips, Bruce Black, Tetsuya Tono, Thomas Linder, John Dornhoffer, Armagan İncesulu
The International Otology Outcome Group (IOOG) was founded in 2017 to encourage and facilitate international collaboration with regard to the surgical outcome of ear surgery. This report outlines the methodology and recommendations of the consensus-based categorization of tympanomastoid surgery produced by the IOOG. The IOOG Steering Committee used the acronym SAMEO-ATO to categorize tympanomastoid operations, representing the stage of surgery, approach, mastoid bone extirpation, external bony wall repair, obliteration of the mastoid cavity, access to the middle ear, tympanic membrane reconstruction, and ossicular reconstruction...
August 3, 2018: Journal of International Advanced Otology
Niels West, Martin Nue Møller, Søren Hansen, Per Cayé-Thomasen
OBJECTIVES: The aim of the present study was to investigate the relationships between tumor size, hearing, and vestibular outcomes in patients with vestibular schwannomas (VSs). MATERIALS AND METHODS: Adult patients (n=124) with unilateral extrameatal VS prior to surgery were included in the study. This was a retrospective cohort study of preoperative audiovestibular investigations including audiometry, discrimination test, caloric test, cervical vestibular evoked myogenic potential (c-VEMP), and ocular vestibular evoked myogenic potential (o-VEMP)...
August 3, 2018: Journal of International Advanced Otology
Ai Matsubara, Takenori Miyashita, Ryuhei Inamoto, Hirofumi Sakaguchi, Toru Kamitani, Nozomu Mori, Hiroshi Hoshikawa
OBJECTIVES: Tricellulin is a tight junction (TJ)-forming protein that participates in the sealing function of tricellular TJs. Tricellulin-knockout (Tric-/-) mice show progressive hearing loss with degeneration of hair cells in the cochlea without physiological or physical disorders. In the present study, we investigated the tricellulin expression and its deletion effects in the endolymphatic sac (ES) using Tric-/- mice. MATERIALS AND METHODS: The ES epithelia from wild-type (WT) mice were laser-microdissected, and RT-PCR was performed...
August 3, 2018: Journal of International Advanced Otology
Yusuke Koide, Masaaki Teranishi, Saiko Sugiura, Yasue Uchida, Yusuke Koide, Naoki Nishio, Ken Kato, Hironao Otake, Tadao Yoshida, Rei Otsuka, Fujiko Ando, Hiroshi Shimokata, Yasuhisa Hasegawa, Tsutomu Nakashima, Michihiko Sone
OBJECTIVES: The pathology of sudden sensorineural hearing loss, which is known as sudden deafness (SD), remains unknown. The purpose of this study was to investigate the association between mitochondrial uncoupling protein 2 (UCP2) polymorphism and SD risk. MATERIALS AND METHODS: We compared 83 patients suffering from SD and 2048 controls who participated in the Longitudinal Study of Aging at the National Institute for Longevity Sciences. Multiple logistic regression was used to calculate the odds ratios (ORs) for SD with a polymorphism of the UCP2 (rs660339) gene...
August 3, 2018: Journal of International Advanced Otology
Ning-Chia Chang, Chia-Yen Dai, Wen-Yi Lin, Hua-Ling Yang, Hsun-Mo Wang, Chen-Yu Chien, Meng-Hsuan Hsieh, Kuen-Yao Ho
OBJECTIVES: Age-related hearing impairment (ARHI) is a major disability among the elderly. This study aimed to analyze the association of single nucleotide polymorphisms (SNPs) of metabotropic glutamate receptor 7 (GRM7) gene with ARHI in an elderly population in Taiwan. MATERIALS AND METHODS: This was a community-based study performed in a metropolitan hospital. Participants ≥65 years of age were recruited. Participants with a pure tone average (PTA) of speech frequencies in the better ear of >35 decibel hearing level (dBHL) were classified into the case group, whereas those with PTA ≤25 dBHL were classified into the control group...
August 3, 2018: Journal of International Advanced Otology
Ahmad Badr, Yousef Shabana, Khaled Mokbel, Ayman Elsharabasy, Mohamed Ghonim, Mario Sanna
OBJECTIVES: While an accurate placement in cochleostomy is critical to ensure appropriate insertion of the cochlear implant (CI) electrode into the scala tympani (ST), the choice of preferred cochleostomy sites widely varied among experienced surgeons. We present a novel technique for precise yet readily applicable localization of the optimum site for performing ST cochleostomy. MATERIAL AND METHODS: Twenty fresh frozen temporal bones were dissected using the mastoidectomy-posterior tympanotomy approach...
August 3, 2018: Journal of International Advanced Otology
Paul Merkus, Pieter Kemp, Fuat Ziylan, Matthew Yung
OBJECTIVES: The aim of this scoping review was to evaluate existing classifications of surgical procedures of the middle ear and mastoid and find a suitable classification that could serve as an international standard. MATERIALS AND METHODS: Scoping review with a systematic literature search using reference tracking and a syntax including all surgical procedures in mastoid and middle ear surgery and their synonyms. Studies were selected based on inclusion and exclusion criteria...
August 3, 2018: Journal of International Advanced Otology
Hjalte Sass, Per Cayé-Thomasen
In light of missing systematic reviews in the literature, the objective of this paper is to present the contemporary knowledge on the molecular biology of vestibular schwannomas (VS), based on a systematic literature search. In addition, current and prospected medical therapy based on molecular biology is addressed. A systematic literature search was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The systematic search was performed in the Pubmed and Embase databases...
August 3, 2018: Journal of International Advanced Otology
William Parkes, Luis Vilchez-Madrigal, Sharon Cushing, Blake Papsin, Adrian James
OBJECTIVES: The natural history of tympanic membrane retraction is unpredictable. To obtain prognostic information for guiding surveillance and treatment, a cohort of children with retraction from cleft palate were prospectively followed for over 5 years. MATERIALS AND METHODS: This was a prospective observational study at a tertiary academic institution. Children with pars tensa retraction were selected from a cohort of 143 children with cleft palate. Thirty-seven ears were assessed with otoendoscopic image capture and audiometry at a median age of 9 years and reassessed at a median follow-up interval of 6...
August 3, 2018: Journal of International Advanced Otology
Wei-Che Lan, Ching-Yuan Wang, Chia-Der Lin
OBJECTIVES: To compare the efficacy of pentoxifylline with that of conventional steroid therapy in diabetic patients with idiopathic sudden sensorineural hearing loss (ISSNHL) and to compare blood sugar levels during hospitalization. MATERIALS AND METHODS: Medical charts were retrospectively reviewed for all diabetic patients admitted to one institution for ISSNHL between 2000 and 2015. We analyzed 298 cases; 50 patients received pulse steroid treatment (steroid group) and 248 received intravenous administration of pentoxifylline only (pentoxifylline group)...
August 3, 2018: Journal of International Advanced Otology
Diane Evrard, Mary Daval, Denis Ayache
Otitis media with effusion (OME) is a very common condition in the current clinical practice. Usually idiopathic, it may sometimes be the consequence of primary diseases. Extracranial meningioma is rare, and even more when involving the ear and temporal bone. We report a case of temporal meningioma spreading to the middle ear and mastoid presenting as an OME. The diagnosis relies on a thorough imaging evaluation with computed tomography and magnetic resonance imaging. This short report aims to warn the otolaryngologist of this rare situation to prevent any delay in diagnosing and managing such a condition...
April 2018: Journal of International Advanced Otology
İsa Kaya, Murat Benzer, Göksel Turhal, Gode Sercan, Cem Bilgen, Tayfun Kirazlı
Giant cell tumor (GCT) is a benign tumor that originates from undifferentiated mesenchymal cells of the bone marrow. The cranium as well as temporal bone is a rare location for GCTs. Despite its benign nature, GCT may be locally aggressive and has the potential to recur locally. Furthermore, GCT may give rise to pulmonary metastases (~1%) in addition to causing local bone destruction. Surgical excision is the treatment of choice for patients with GCT. We describe the case of a 56-year-old female who presented with headache and hearing loss with extensive GCT, which originated in the squamous part of the temporal bone and extended into the left mandibular fossa and middle ear...
April 2018: Journal of International Advanced Otology
Goh Eui-Kyung, Cho Ilyoung, Oh Se-Joon, Choi Sung-Won, Kim Young-Keum
An inverted papilloma is a benign neoplasm that occurs exclusively in the sinonasal cavity; an inverted papilloma involving the mastoid cavity is extremely rare. We present the case of a patient with an inverted papilloma of the mastoid cavity secondary to cholesteatoma surgery. No case that occurred after acquired cholesteatoma has been reported in literature. A 39-year-old female who was diagnosed with cholesteatoma was treated with a modified radical mastoidectomy in 1988. After recurrence, the patient underwent a canal wall down mastoidectomy in 2006...
April 2018: Journal of International Advanced Otology
Young Eun Han, Yong Seok Kang, Younhoon Cho, Moo Kyun Park
Eosinophilic otitis media (EOM) are intractable otitis media characterized by highly viscous secretions containing eosinophils in the middle ear. They are resistant to conventional medication and surgery. This condition occurs primarily in patients with bronchial asthma or allergic rhinitis and is often complicated by rhinosinusitis. Systemic and topical steroid therapies are effective treatments. However, long-term steroid therapy is often limited by a high risk of serious adverse effects. The use of topical steroids and otorrhea are bothersome when wearing hearing aids...
April 2018: Journal of International Advanced Otology
Yasser Ahmed Fouad, Thomas Roland
This clinical report describes and evaluates a novel periosteal flap design. This technique was applied in 26 patients who underwent cochlear implantation surgery at two tertiary referral centers. No complications were observed during or after the surgery. Additionally, there was no evidence of device migration, wound infection, wound hematoma, or delayed wound healing. Notably, the mastoid emissary vein was intact in all cases. In conclusion, this modified anterior-based periosteal flap is a safe procedure and is aimed at avoiding mastoid emissary vein bleeding and allowing complete repositioning of the periosteum over the implanted device...
April 2018: Journal of International Advanced Otology
Matti Iso-Mustajärvi, Aarno Dietz, Heikki Löppönen
OBJECTIVE: The aim of this study was to evaluate and compare myringoplasty results from two different consecutive series conducted at the Kuopio University Hospital during a four-decade period. MATERIALS AND METHODS: We reviewed 315 patients (a total of 338 ears) who underwent myringoplasty at Kuopio University Hospital between the years 1986 and 2012. The results from this series were compared with those form a previously published series of 404 patients who underwent myringoplasty between 1970 and 1985 at the same institution...
April 2018: Journal of International Advanced Otology
Alba Marina Milá de la Roca-Morales, Joan F Andreo-Marroig, Sofía Santos-Pérez, Andrés Soto-Varela
OBJECTIVE: To describe the pattern of dynamic posturography or its role in diagnosis in patients with cerebellar ataxia with neuropathy and vestibular arreflexia syndrome (CANVAS). MATERIALS AND METHODS: We present and describe posturographic data of four patients diagnosed with the CANVAS syndrome in a tertiary hospital. RESULTS: In all patients, the average balance score was diminished. Two patients presented a pattern of visual dependence...
April 2018: Journal of International Advanced Otology
Veera Luukkainen, Ilkka Kivekäs, Juha Silvola, Jussi Jero, Saku T Sinkkonen
Balloon Eustachian tuboplasty (BET) aims to improve the function of the Eustachian tube (ET). The objective of this study was to review the long-term outcome of BET and present the process and results of outlining indications for BET by the Finnish Otosurgical Society. The literature review is based on a database search performed in May 2017. The search resulted in 100 individual articles, which were screened for relevance. Five articles fulfilled the inclusion criteria (follow-up ≥12 months). Five additional articles (follow-up, 6-11 months) were analyzed to obtain supportive information...
April 2018: Journal of International Advanced Otology
Francesco Comacchio, Marta Mion
The goal of the present study was to describe a case of perilymphatic fistula (PLF) of the round window (RW) that occurred after sneezing, along with a review of the literature. We report a case of PLF of RW, which was provoked by sneezing, and its consequent medical and surgical treatments. With respect to the review of the literature, articles were initially selected based on their titles or abstracts, followed by methodological evaluation. The patient underwent an explorative tympanotomy (ET) with packaging of RW with the pericondrium, following which the patient's complaints regarding vertigo and imbalance disappeared, but the severe sensorineural hearing loss persisted...
April 2018: Journal of International Advanced Otology
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