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Infectious Diseases

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https://www.readbyqxmd.com/read/28152654/community-acquired-versus-healthcare-associated-staphylococcus-aureus-bacteraemia-among-children-in-a-tropical-region
#1
Eulina S Andrade, Renata T Gomes, Ticiana G Lyra, Cristiana M Nascimento-Carvalho
No abstract text is available yet for this article.
February 2, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28135900/penicillin-susceptible-staphylococcus-aureus-susceptibility-testing-resistance-rates-and-outcome-of-infection
#2
Malin Hagstrand Aldman, Annette Skovby, Lisa I Påhlman
BACKGROUND: Staphylococcus aureus (SA) is an important human pathogen that causes both superficial and invasive infections. Penicillin is now rarely used in the treatment of SA infections due to widespread resistance and a concern about the accuracy of existing methods for penicillin susceptibility testing. The aims of the present study were to determine the frequency of penicillin-susceptible SA isolates from blood and wound cultures in Lund, Sweden, and to evaluate methods for penicillin testing in SA...
January 30, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28127992/predictors-of-drug-sensitive-tuberculosis-treatment-outcomes-among-hospitalized-patients-in-south-africa-a-multinomial-logit-model
#3
Abiola O Olaleye, Andy K Beke
No abstract text is available yet for this article.
January 27, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28121214/evaluation-of-the-performance-of-tuberculin-skin-test-and-quantiferon-tb-gold-in-tube-test-in-patients-with-hematologic-malignancies
#4
Panagiotis T Diamantopoulos, Gerasimos D Tsilimidos, Konstantinos Zervakis, Katerina Polonyfi, Maria Sofotasiou, Marie-Christine Kyrtsonis, Athanasios Aessopos, Georgios Kyriakakis, Nora A Viniou
No abstract text is available yet for this article.
January 25, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28116970/relevance-of-indeterminate-clostridium-difficile-screening-tests-with-detectable-toxin-genes-colonization-or-c-difficile-disease
#5
Gordana Simeunovic, Mamta Sharma, Kathleen Riederer, Riad Khatib
No abstract text is available yet for this article.
January 24, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28116961/primary-versus-non-primary-maternal-cytomegalovirus-infection-as-a-cause-of-symptomatic-congenital-infection-register-based-study-from-finland
#6
Laura Puhakka, Marjo Renko, Merja Helminen, Ville Peltola, Tarja Heiskanen-Kosma, Maija Lappalainen, Heljä-Marja Surcel, Tuula Lönnqvist, Harri Saxen
BACKGROUND: Both primary and non-primary maternal cytomegalovirus (CMV) infection during pregnancy can lead to vertical transmission. We evaluated the proportion of maternal primary/non-primary infections among 26 babies with symptomatic congenital CMV infection born in Finland from 2000 to 2012. METHODS: We executed a database search on hospital records from all five university hospitals in Finland to identify infants with congenital CMV infection. The preserved maternal serum samples drawn at the end of the first trimester were analysed for CMV antibodies...
January 24, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28116958/the-role-of-quantiferon-tb-gold-in-tube-in-the-diagnosis-and-treatment-monitoring-of-active-tuberculosis
#7
Filippo Bartalesi, Michele Spinicci, Jessica Mencarini, Sara Veloci, Antonia Mantella, Alessandro Bartoloni
No abstract text is available yet for this article.
January 24, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28116950/a-combination-of-ceftaroline-and-daptomycin-has-synergistic-and-bactericidal-activity-in-vitro-against-daptomycin-nonsusceptible-methicillin-resistant-staphylococcus-aureus-mrsa
#8
Iffat Shafiq, Zackery P Bulman, Sarah L Spitznogle, Justin E Osorio, Irene S Reilly, Alan J Lesse, Ganapathi I Parameswaran, Kari A Mergenhagen, Brian T Tsuji
There is an urgent need to optimize therapeutic options in patients with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia who have failed conventional therapy. Two clinical isolates were obtained from a 68-year-old male with persistent MRSA bacteremia before and after the development of daptomycin nonsusceptibility. The pharmacodynamic activity of monotherapies and combinations of ceftaroline, daptomycin, cefoxitin, nafcillin and vancomycin were evaluated in time-kill experiments versus 10(8) CFU/mL of the pre- and post-daptomycin nonsusceptible MRSA isolates...
January 24, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28095723/increased-long-term-mortality-after-survival-of-invasive-pneumococcal-disease-a-population-based-study
#9
Hans Kristian Floeystad, Are Holm, Leiv Sandvik, Didrik Frimann Vestrheim, Bjorn Brandsaeter, Dag Berild
OBJECTIVES: We studied if patients surviving hospitalization for invasive pneumococcal disease (IPD) have an increased long-term mortality. METHODS: In this population-based case-control study, we assessed adults discharged from Aker University Hospital in Oslo, Norway, from 1993 to 2008 after surviving IPD. Mortality among the study population was compared to the general Norwegian population using standardized mortality ratios (SMR). Median follow-up time was 7...
January 17, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28092204/impact-of-combination-therapy-and-early-de-escalation-on-outcome-of-ventilator-associated-pneumonia-caused-by-pseudomonas-aeruginosa
#10
Laurène Deconinck, Agnès Meybeck, Pierre Patoz, Nicolas Van Grunderbeeck, Nicolas Boussekey, Arnaud Chiche, Pierre-Yves Delannoy, Hugues Georges, Olivier Leroy
BACKGROUND: Pseudomonas aeruginosa is a common cause of ventilator-associated pneumonia (VAP). Guidelines recommend dual coverage of P. aeruginosa, but the beneficial effect of combination therapy is controversial. We described antibiotic prescriptions and evaluated the clinical impact of initial combination antibiotic therapy and de-escalation strategy in patients with VAP caused by P. aeruginosa. METHODS: Between 1994 and 2014, all 100 patients with VAP caused by P...
January 16, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28077007/accurate-and-fast-urinalysis-in-febrile-patients-by-flow-cytometry
#11
Foppie J de Boer, Elske Gieteling, Heidi van Egmond-Kreileman, Bijan Moshaver, Sjef J C M van der Leur, Coen A Stegeman, Paul H P Groeneveld
BACKGROUND: The urine culture is worldwide accepted as the gold standard in diagnosing urinary tract infections, but is time consuming and costly, other methods are fast but moderately reliable. We investigated whether counting the number of bacteria by flow cytometry could be a fast and accurate method to analyze urine samples in febrile patients at the emergency department (ED). METHODS: Urine samples were obtained from 140 febrile patients at the ED. Urinalysis was performed according to standard procedures...
January 11, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28077005/corrigendum
#12
(no author information available yet)
No abstract text is available yet for this article.
January 11, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28071193/screening-of-esbl-producing-enterobacteriacae-concomitant-with-low-degree-of-transmission-in-intensive-care-and-bone-marrow-transplant-units
#13
Giuseppe Valenza, Monika Schulze, Petra Friedrich, Wulf Schneider-Brachert, Thomas Holzmann, Silke Nickel, Verena Lehner-Reindl, Christiane Höller
BACKGROUND: Extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E) are spreading worldwide in both hospital and community settings. In this study, the molecular epidemiology and the transmission modalities of ESBL-E in intensive care- and bone marrow transplant were investigated. METHODS: All patients included in this study were screened for presence of ESBL-E on admission and weekly. Relevant β-lactamase genes were identified by PCR and sequencing...
January 10, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28067093/rotavirus-epidemiology-5-6-years-after-universal-rotavirus-vaccination-persistent-rotavirus-activity-in-older-children-and-elderly
#14
Jukka Markkula, Maria Hemming-Harlo, Marjo T Salminen, Carita Savolainen-Kopra, Jaana Pirhonen, Haider Al-Hello, Timo Vesikari
BACKGROUND: Rotavirus (RV) vaccination using RotaTeq(®) vaccine exclusively was introduced into Finnish National Immunization Program (NIP) in 2009, and soon reached high (≥90%) coverage. Since mid-2013, all stool samples from laboratory diagnosed cases of RV gastroenteritis in the entire country have been typed. METHODS: 364 RV positive stool samples collected from clinical laboratories over a 2-year period were G- and P-typed using RT-PCR, and the results were confirmed by sequencing...
January 9, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28049383/a-lyme-borreliosis-diagnosis-probability-score-no-relation-with-antibiotic-treatment-response
#15
Violeta T Briciu, Mirela Flonta, Daniel Leucuţa, Dumitru Cârstina, Doina F Ţăţulescu, Mihaela Lupşe
OBJECTIVES: (1) To describe epidemiological and clinical data of patients that present with the suspicion of Lyme borreliosis (LB); (2) to evaluate a previous published score that classifies patients on the probability of having LB, following-up patients' clinical outcome after antibiotherapy. METHODS: Inclusion criteria: patients with clinical manifestations compatible with LB and Borrelia (B.) burgdorferi positive serology, hospitalized in a Romanian hospital between January 2011 and October 2012...
January 3, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28049382/use-of-intracranial-pressure-monitoring-in-bacterial-meningitis-a-10-year-follow-up-on-outcome-and-intracranial-pressure-versus-head-ct-scans
#16
Lykke Larsen, Frantz R Poulsen, Troels H Nielsen, Carl-Henrik Nordström, Mette K Schulz, Åse B Andersen
BACKGROUND: The aim of this study was to evaluate the clinical outcome of patients with severe bacterial meningitis where intracranial pressure (ICP) monitoring has been performed. METHODS: A retrospective observational study including patients admitted 1st(.) January 2005 to 31st(.) December 2014. Thirty nine patients age 18-89 years were included. All the patients received intensive care with mechanical ventilation, ICP monitoring, sedation, antibiotics and corticosteroids according to current guidelines...
January 3, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28049381/kidney-disease-in-puumala-hantavirus-infection
#17
Jukka Mustonen, Tuula Outinen, Outi Laine, Ilkka Pörsti, Antti Vaheri, Satu Mäkelä
Acute kidney injury (AKI) remains a predominant clinical expression of nephropathia epidemica (NE). Its pathogenesis is not yet fully understood. Here, we describe the tissue injury comprehensively and present new data aimed to characterize the injury and explain its pathophysiology. When compared to tubulointerstitial nephritis of a wide variety of other aetiologies, a high degree of proteinuria is a distinguished trait of NE, a finding that is also helpful in the clinical suspicion of the disease. Recently, novel biomarkers for the prediction of severe AKI, including neutrophil gelatinase-associated lipocalin (NGAL), have been identified and ultrastructural tissue changes have been more accurately described...
January 3, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28049378/isolation-of-escherichia-coli-st131-producing-kpc-2-in-bulgaria
#18
Rumyana Markovska, Temenuga Stoeva, Lyudmila Boyanova, Petya Stankova, Daniela Pencheva, Radka Kaneva, Vanyo Mitev, Ivan Mitov
No abstract text is available yet for this article.
January 3, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28024452/positive-predictive-value-of-elispot-in-bal-and-pleural-fluid-from-patients-with-suspected-pulmonary-tuberculosis
#19
Regina W Hofland, Steven F T Thijsen, Anne S R van Lindert, Wiel C M de Lange, Tamara van Gorkom, Ingeborg van der Tweel, Jan-Willem J Lammers, Aik W J Bossink
BACKGROUND: The aim of this study was to evaluate the positive predictive value (PPV) of ELISpot in bronchoalveolar lavage (BAL) and pleural fluid for the diagnosis of active tuberculosis (TB) in real-life clinical practice, together with the added value of a cut-off >1.0 for the ratio between the extra-sanguineous and systemic interferon-gamma responses in positive samples. METHODS: A retrospective, single-centre study was performed. Patients with positive ELISpot in BAL and pleural fluid were included...
December 26, 2016: Infectious Diseases
https://www.readbyqxmd.com/read/27973976/where-to-look-for-the-scabies-mite
#20
Stefano Veraldi, Luigi Esposito, Paolo Pontini, Gianluca Nazzaro, Rossana Schianchi
No abstract text is available yet for this article.
December 15, 2016: Infectious Diseases
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