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Infectious Diseases

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https://www.readbyqxmd.com/read/28316268/hepatitis-b-mother-to-child-transmission-and-infants-immunization-we-have-not-come-to-the-end-of-the-story-yet
#1
Guglielmo Borgia, Alberto Enrico Maraolo, Ivan Gentile
No abstract text is available yet for this article.
March 20, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28298163/pet-ct-added-to-duke-criteria-facilitates-diagnosis-and-monitoring-of-long-term-suppressive-therapy-of-prosthetic-endocarditis
#2
Pedro Puerta-Alcalde, Guillermo Cuervo, Antonella F Simonetti, Laura Gracia-Sánchez, Daniel Ortiz, Carolina Garcia-Vidal
No abstract text is available yet for this article.
March 16, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28293975/human-papillomavirus-prevalence-in-mouthwashes-of-patients-undergoing-tonsillectomy-shows-dominance-of-hpv69-without-the-corresponding-finding-in-the-tonsils
#3
Nathalie Grün, Wilbert Mbuya, Anders Ternhag, Torbjörn Ramqvist, Alexander Ahlberg, Mattias Jangard, Tina Dalianis, Lalle Hammarstedt-Nordenvall
BACKGROUND: The role of human papillomavirus (HPV) in tonsillar squamous cell carcinomas (TSCC) is of interest, since a considerable proportion of TSCC in Sweden and other Western countries is HPV positive. Nevertheless, the natural history of HPV in normal tonsils, and the progression from localized infection to pre-malignant lesion to cancer are poorly understood. The aim of this study was to investigate whether HPV types found in mouthwash samples correlated to those in tonsillar tissue from the same individuals undergoing tonsillectomy...
March 15, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28293974/treatment-of-hepatitis-c-virus-infection-updated-swedish-guidelines-2016
#4
Martin Lagging, Rune Wejstål, Gunnar Norkrans, Olle Karlström, Soo Aleman, Ola Weiland, Maria Castedal, Johan Westin
In a recent expert meeting, Swedish recommendations for the treatment of hepatitis C virus (HCV) infection were updated. An interferon-free combination of direct-acting antiviral agents is considered and indicated for all patients with chronic HCV infection, but the ability to treat all is limited primarily by high cost of medication. The group of patients prioritized for therapeutic intervention has been extended to also include fertile women desiring to become pregnant. A more thorough discussion of treatment for people who inject drugs (PWIDs) in order to diminish transmission is included, and the clinical significance of baseline NS5A resistance associated variants (RAVs), also known as resistance associated substitutions (RASs), for the treatment of HCV genotype 1a or 3 infection is discussed...
March 15, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28293958/successful-salvage-treatment-of-native-valve-enterococcus-faecalis-infective-endocarditis-with-telavancin-two-case-reports
#5
Mickala M Thompson, Ali Hassoun
Infective endocarditis (IE) one-year mortality rates approach 40%. Here, we report two native valve Enterococcus faecalis IE cases in patients successfully treated with telavancin. An 88-year-old with mitral valve endocarditis and a penicillin allergy, initially treated with intravenous vancomycin, was switched to telavancin. A 69-year-old, who previously received amoxicillin and intravenous vancomycin for presumed enterococcal bacteraemia, was diagnosed with dual valve endocarditis for which he received telavancin...
March 15, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28276281/in-vitro-susceptibility-and-resistance-phenotypes-in-contemporary-citrobacter-isolates-in-a-university-hospital-in-crete-greece
#6
Sofia Maraki, Konstantinos Z Vardakas, Viktoria-Eirini Mavromanolaki, Margarita Kyriakidou, George Spais, Diamantis P Kofteridis, George Samonis, Matthew E Falagas
BACKGROUND: Data on Citrobacter spp. susceptibility are scarce. We sought to study the evolution in the susceptibility of 385 Citrobacter spp. at the University Hospital of Heraklion, Crete, Greece during a six-year period (2010-2015). METHODS: Non-duplicate strains isolated from inpatients (intensive care unit, oncology, surgery, internal medicine, paediatrics) and outpatients were studied using Vitek 2. Phenotypic confirmatory tests were applied for detection of β-lactamases and aminoglycoside modifying enzymes...
March 9, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28264618/assessment-of-early-combination-effects-of-colistin-and-meropenem-against-pseudomonas-aeruginosa-and-acinetobacter-baumannii-in-dynamic-time-kill-experiments
#7
Thomas Tängdén, Matti Karvanen, Lena E Friberg, Inga Odenholt, Otto Cars
BACKGROUND: In view of the paucity of clinical evidence, in vitro studies are needed to find antibiotic combinations effective against multidrug-resistant Gram-negative bacteria. Interpretation of in vitro effects is usually based on bacterial growth after 24 h in time-kill and checkerboard experiments. However, the clinical relevance of the effects observed in vitro is not established. In this study we explored alternative output parameters to assess the activities of colistin and meropenem against Pseudomonas aeruginosa and Acinetobacter baumannii...
March 6, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28264610/corynebacterium-species-causing-breast-abscesses-among-patients-attending-a-tertiary-care-hospital-in-chennai-south-india
#8
Indira Poojary, Ann Kurian, Jayalekshmi V A, Debora Devapriya J, Thirunarayan M A
BACKGROUND: Corynebacterium species other than Corynebacterium diphtheriae were mostly considered contaminants in the past, but there are reports of their association with wide variety of human infections lately. In this study, we look into Corynebacterium species isolated from breast abscess patients and assess their antimicrobial susceptibility pattern and treatment outcomes. MATERIAL AND METHODS: Pus samples from suspected breast abscess cases were examined from October 2014 to September 2015...
March 6, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28264598/review-of-the-pharmacokinetics-of-dalbavancin-a-recently-approved-lipoglycopeptide-antibiotic
#9
Ranjeet Prasad Dash, R Jayachandra Babu, Nuggehally R Srinivas
Dalbavancin, a recently approved glycopeptide antibiotic, whose disposition is not affected by renal function as compared to vancomycin is used to treat serious infections caused by Staphylococci and Streptococci including multiple drug-resistant strains. Although reviews of the pharmacodynamic and clinical efficacy of dalbavancin have been published, a comprehensive overview of the pharmacokinetic properties including distribution and disposition in animals and humans has not been published. The aim of this review is to summarize the pharmacokinetics of dalbavancin, which justifies the intravenous dosing regimens and to provide considerations and perspectives with regard to dosing strategies...
March 6, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28276798/usefulness-of-urine-culture-from-healthy-non-pregnant-women-with-uncomplicated-cystitis
#10
Stephanie Knudtzon, Jørgen Knudtzon
No abstract text is available yet for this article.
March 3, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28276797/old-enemies-in-new-disguises-emergence-of-enterococcus-faecium-as-a-significant-clinical-problem-at-an-adult-haematology-ward
#11
Sari Hämäläinen, Jaana Pentikäinen, Jori Reijula, Ella Mauranen, Irma Koivula, Laura Lindholm, Auni Juutilainen, Tapio Nousiainen, Marja Pyörälä, Jaana Vuopio, Esa Jantunen
No abstract text is available yet for this article.
March 3, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28276796/a-comprehensive-search-for-microbial-dna-and-rna-in-sarcoidosis-tissue-samples-by-quantitative-polymerase-chain-reaction
#12
Fumio Terasaki, Hitomi Fukumoto, Ryo Kawata, Yoshinobu Hirose, Shu-Ichi Fujita, Harutaka Katano, Nobukazu Ishizaka
No abstract text is available yet for this article.
March 3, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28276795/influence-of-the-fabric-colour-for-the-ticks-ixodes-ricinus-and-dermacentor-reticulatus-attachment
#13
Anna Szczepańska, Dorota Kiewra, Elżbieta Lonc
No abstract text is available yet for this article.
March 3, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28276794/insufficient-efficacy-and-safety-of-intravenous-ribavirin-in-treatment-of-haemorrhagic-fever-with-renal-syndrome-caused-by-puumala-virus
#14
Oleg V Malinin, Alexander E Platonov
BACKGROUND: Intravenous ribavirin has been reported to be an effective treatment for haemorrhagic fever with renal syndrome (HFRS) caused by Hantaan virus in Asia. However, its therapeutic benefits for HFRS caused by Puumala virus (PUUV) in Europe are still unknown. METHODS: A randomized, open-label study of efficacy and safety of intravenous ribavirin in the treatment of HFRS was conducted in the European part of Russia. Seventy-three patients with suspected HFRS within 4 d of the onset of the disease were randomized to receive either intravenous ribavirin (33 mg/kg, followed by 16 mg/kg given every 6 h for 4 d and by 8 mg/kg given every 8 h for 3 d) plus standard therapy (n = 37) or standard therapy alone (n = 36)...
March 3, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28276793/lack-of-polymyxin-resistance-among-carbapenemase-producing-enterobacteriaceae-in-a-university-hospital-in-china
#15
Xiaofei Jiang, Laurent Poirel, Patrice Nordmann
No abstract text is available yet for this article.
March 3, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28276800/sepsis-alert-a-triage-model-that-reduces-time-to-antibiotics-and-length-of-hospital-stay
#16
Mari Rosenqvist, Emma Fagerstrand, Peter Lanbeck, Olle Melander, Per Åkesson
OBJECTIVE: To study if a modified triage system at an Emergency Department (ED) combined with educational efforts resulted in reduced time to antibiotics and decreased length of hospital stay (LOS) for patients with severe infection. METHODS: A retrospective, observational study comparing patients before and after the start of a new triage model at the ED of a University Hospital. After the implementation of the model, patients with fever and abnormal vital signs were triaged into a designated sepsis line (Sepsis Alert) for rapid evaluation by the attending physician supported by a infectious diseases (IDs) specialist...
February 28, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28276799/comparison-of-outcome-and-clinical-characteristics-of-bacteremia-caused-by-methicillin-resistant-penicillin-resistant-and-penicillin-susceptible-staphylococcus-aureus-strains
#17
Elina Jokinen, Janne Laine, Reetta Huttunen, Pekka Rahikka, Heini Huhtala, Risto Vuento, Jaana Vuopio, Jaana Syrjänen
BACKGROUND: The aim of this study was to assess the association of methicillin resistance and penicillinase production with clinical characteristics and outcome of Staphylococcus aureus bacteremia. METHODS: For 126 patients with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia, 378 age- and gender-matched controls with methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia were selected. Of controls, 126 had bacteremia caused by penicillin-susceptible strains (PSSA) and 252 by penicillinase-producing strains (PRSA)...
February 28, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28276803/failure-to-reach-therapeutic-levels-of-rifampicin-and-isoniazid-by-recommended-dosages
#18
Prerna K Chawla, Rohan V Lokhande, Prasad R Naik, Alpa J Dherai, Rohit A Amale, Zarir F Udwadia, Ashok A Mahashur, Rajeev Soman, Tester F Ashavaid
No abstract text is available yet for this article.
February 19, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28276802/no-response-to-hepatitis-b-vaccine-in-infants-born-to-hbsag-mothers-is-associated-to-the-transplacental-transfer-of-hbsag
#19
Jing Wang, Yingli He, Dongfang Jin, Jinfeng Liu, Jie Zheng, Ningxia Yuan, Yun Bai, Taotao Yan, Yuan Yang, Yong Liu, Shulin Zhang, Yingren Zhao, Tianyan Chen
BACKGROUND: No or low hepatitis B (HB) vaccine response is more frequent in infants from HBsAg(+) mothers than those from HBsAg(-). Our previous study found temporary positivity of HBsAg in infants from HBsAg(+) mothers. In this study, we hypothesized that HBsAg in infant blunt immune response to standard hepatitis B vaccination. METHODS: A total of 328 consecutive HBsAg(+) mothers and their offspring were enrolled. Blood samples were taken from mothers and their infants and quantified for HBsAg, anti-HBs titer and HBV DNA load concentration; Placenta samples were collected to stain for HBsAg...
February 19, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28276801/tuberculosis-infection-and-disease-in-the-2015-cohort-of-unaccompanied-minors-seeking-asylum-in-northern-stockholm-sweden
#20
Rutger Bennet, Margareta Eriksson
BACKGROUND: Minors with a stated age <18 years unaccompanied by a responsible adult form an increasing part of refugees to Europe. They are older than other asylum-seeking children and many come from countries with a high tuberculosis (TB) incidence. During the 2015 refugee crisis, 35,369 of 162,877 refugees (22%) seeking asylum in Sweden were unaccompanied minors, which gave us the opportunity to study their burden of TB infection and disease. METHODS: Of the unaccompanied minors seeking asylum in Sweden during 2015, 2936 (8...
February 19, 2017: Infectious Diseases
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