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Infectious Diseases

Virginie Zarrouk, Julien Gras, Vincent Dubée, Victoire de Lastours, Amanda Lopes, Véronique Leflon, Wassim Allaham, Pierre Guigui, Bruno Fantin
No abstract text is available yet for this article.
May 10, 2018: Infectious Diseases
Arne Nørgaard Eskesen, Margrethe Astrup Belle, Anita Blomfeldt
OBJECTIVES: Staphylococcus aureus bacteraemia (SAB) is a common infection associated with significant short-term mortality. Little is known about long-term prognosis. The aim of this study was to determine one-year all-cause mortality and infection-related mortality and associated predictors. METHODS: Data from 303 consecutive patients with SAB were prospectively collected from March 2011 to February 2014. All patients were followed one year or until death. RESULTS: One-year all-cause- and infection-related mortality were 36...
May 10, 2018: Infectious Diseases
Anna Celotti, Fabrizio Vianello, Andrea Sattin, Giacomo Malipiero, Roberto Faggin, Annamaria Cattelan
No abstract text is available yet for this article.
April 28, 2018: Infectious Diseases
Jeongmin Hong, Seung Hyun Lee, Byung-Han Ryu, Min Jae Kim, Kyung-Wook Jo, Yong Pil Chong, Sang-Oh Lee, Sang-Ho Choi, Tae Sun Shim, Yang Soo Kim, Jun Hee Woo, Sung-Han Kim
No abstract text is available yet for this article.
April 28, 2018: Infectious Diseases
Paschalina Kontou, Maria Papaioannou, Anastasia Dimaki, Zoi Bosmou, Militsa Bitzani, Ioannis Kioumis
No abstract text is available yet for this article.
April 28, 2018: Infectious Diseases
Justo Sandino Pérez, Ana Maria Mancilla, Edgar Pérez Barragán, Mario Fernández-Ruiz
No abstract text is available yet for this article.
April 25, 2018: Infectious Diseases
Jimmy Jörgensen, Fredrik Månsson, Håkan Janson, Ann Cathrine Petersson, Anna C Nilsson
BACKGROUND: Colonization with methicillin-resistant Staphylococcus aureus (MRSA) can cause endogenously derived infections and be a source of transmission to other people. Neither colonization time of asymptomatic MRSA colonization nor the effect of treatment aiming at MRSA eradication in children has been thoroughly investigated. METHODS: Two hundred ninety-three children <18 years in the mandatory follow-up program for MRSA-carriers in Malmö, Sweden were evaluated...
April 24, 2018: Infectious Diseases
Dafne C Andrade, Igor C Borges, Maiara L Bouzas, Juliana R Oliveira, Helena Käyhty, Olli Ruuskanen, Cristiana Nascimento-Carvalho
BACKGROUND: We studied Immunoglobulin G (IgG) antibody responses against Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis in young children with acute viral type respiratory infection and analyzed the findings in a multivariate model including age, nasopharyngeal carriage of the tested bacteria and pneumococcal vaccination. METHODS: We included 227 children aged 6-23 months with acute respiratory infection. Nasopharyngeal aspirates were tested for bacterial carriage through detection of messenger RNA (mRNA) transcript with nCounter analysis...
April 24, 2018: Infectious Diseases
Daniel Bengtsson, Martin Westerberg, Susanne Nielsen, Malin Ridell, Bodil Jönsson
BACKGROUND: Previous studies have identified patients infected with Mycobacterium chimaera (M. chimaera) subsequent to cardiac surgery. Water tanks in heater-cooler units (HCUs) used cardiac heart surgery was traced as source. The aim was to investigate occurrence of M. chimaera and other microorganisms in HCUs and evaluate the silver-ion cleaning routine. METHOD: Five HCUs were disinfected with silver-ions and examined for mycobacteria directly (15 min) after the disinfection procedures and later on three occasions (3, 6, 10 weeks)...
April 24, 2018: Infectious Diseases
Luciete A Silva, Beatriz Coronato, Jessica Schlackman, Jane W Marsh, Chinelo Ezeonwuka, Andréia C L Fernandes, Victor C Souza, Lirna S da Silva, Elaine F Q de Amorim, Felipe G Naveca, Bernardino C de Albuquerque, Alcirene Amaral, Ana L S Souza, Filipe A Carvalho-Costa, Mustapha M Mustapha, Lee H Harrison, David E Barroso
BACKGROUND: The aim of this study is to describe the molecular epidemiology of Neisseria meningitidis invasive disease before the introduction of serogroup C conjugate vaccine in Amazonas State in 2010. METHODS: Meningococcal disease reported cases were investigated in Amazonas State during the period 2000-2010. N. meningitidis isolates (n = 196) recovered from patients were genotyped by multilocus sequence typing (MLST) and sequencing of porB, porA, fetA, fHbp and penA...
April 6, 2018: Infectious Diseases
O Olsson, N Winqvist, M Olsson, P Olsson, P Björkman
BACKGROUND/AIM: Treatment of latently infected individuals at increased risk of reactivation is a cornerstone in tuberculosis control. Although asylum seekers without residence permit in Sweden are offered screening for both active tuberculosis and latent tuberculosis infection (LTBI), treatment for LTBI is often not initiated due to anticipated low rates of treatment completion. We aimed to compare completion rates for LTBI treatment between asylum seekers and other patients, and between asylum seekers with and without residence permit...
April 5, 2018: Infectious Diseases
Sara Melo Oliveira, Manuel Gonçalves-Pinho, Alberto Freitas, Hercília Guimarães, Inês Azevedo
BACKGROUND: Pertussis has caused several outbreaks and concern worldwide. Despite high vaccination coverage, people of all ages are still affected with significant morbidity and mortality. We aimed to analyse all pertussis hospitalizations in Portugal to help to delineate preventive policies. METHODS: Data were collected from a Portuguese administrative database, which contains all registered hospitalizations in mainland Portugal. Cases were identified using the ICD-9-CM code 033...
April 4, 2018: Infectious Diseases
A Mizrahi, J Amzalag, C Couzigou, G Péan De Ponfilly, B Pilmis, A Le Monnier
BACKGROUND: Bloodstream infections (BSI) can potentially be life-threatening infections and are associated with a high crude mortality, moreover with an inappropriate first-line antibiotic therapy. Bacterial resistance is more and more frequently observed. New strategies of BSI management are urgently needed. MATERIALS AND METHODS: During an 18-months period, we prospectively evaluated the clinical impact of rapid bacterial identification by MALDI-TOF MS technology combined with an antimicrobial stewardship team (AST) intervention...
April 2, 2018: Infectious Diseases
Sajjad Zamanlou, Mohammad Ahangarzadeh Rezaee, Mohammad Aghazadeh, Reza Ghotaslou, Farhad Babaie, Younes Khalili
INTRODUCTION: The wide distribution of extended-spectrum β-lactamase (ESBL) producing Shigella spp., along with the emergence of fluoroquinolone resistant isolates, is a serious threat to public health, posing a new challenge for the effective treatment of shigellosis. The purpose of this study was to determine the level of antimicrobial resistance, the presence of genes encoding resistance to cephalosporins, and plasmid-mediated quinolone resistance (PMQR) among the clinical isolates of Shigella spp...
March 29, 2018: Infectious Diseases
Feng Shen, Chao Han, Mao-Shui Wang, Yu He
No abstract text is available yet for this article.
March 23, 2018: Infectious Diseases
Camille de Seynes, Bertille de Barbeyrac, Hervé Dutronc, Clément Ribes, Paul Crémer, Véronique Dubois, Thierry Fabre, Michel Dupon, Frédéric-Antoine Dauchy
BACKGROUND: Prosthetic joint infection (PJI) is a severe complication of orthopaedic surgery. Preoperative diagnosis, although sometimes difficult, is key to choose the relevant treatment. METHODS: We conducted a prospective study aimed at evaluating the diagnostic performance of a multiplex serological test for the pre-operative diagnosis of PJI. Blood samples were collected between 1 July 2016 and 31 July 2017 among patients referred for suspected PJI that occurred at least six weeks prior...
March 22, 2018: Infectious Diseases
Tanya Strateva, Ivo Sirakov, Svetoslav Dimov, Angelina Trifonova, Encho Savov, Ivan Mitov
No abstract text is available yet for this article.
March 21, 2018: Infectious Diseases
Swati Sharma, Beena Uppal, Vikas Manchanda, Anuj Sud
No abstract text is available yet for this article.
March 19, 2018: Infectious Diseases
Shinichiro Morioka, Mika Ichikawa, Keita Mori, Hanako Kurai
BACKGROUND: Coagulase-negative staphylococci (CoNS) are the most common contaminants of blood cultures, however, we sometimes have difficulties in determining their clinical significance. It is still controversial that there is a significant difference between the contamination group and the true bacteraemia group in the time to positivity (TTP) of blood cultures. We validated the relationship between a TTP and the presence of CoNS bacteraemia in cancer patients by using an objective, non-judgmental definition for CoNS contamination...
March 16, 2018: Infectious Diseases
Bei Jia, Weihua Wu, Rui Huang, Guiyang Wang, Peixin Song, Yang Li, Yong Liu, Yali Xiong, Xiaomin Yan, Yingying Hao, Juan Xia, Zhaoping Zhang, Yuxin Chen, Chao Wu
BACKGROUND: Severe fever with thrombocytopenia syndrome (SFTS) is a life-threatening infectious disease identified in 2009. SFTS is mainly transmitted by contact with ticks or animals; however, sporadic reports suggested that SFTS could be transmitted among humans. OBJECTIVES: We aimed to comprehensively characterize clinical features and disease progression of SFTS acquired by human-to-human transmission. STUDY DESIGN: A retrospective study of 90 SFTS patients was performed in a tertiary hospital of Nanjing, China, from October 2010 to October 2016...
March 15, 2018: Infectious Diseases
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