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Infectious Diseases

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https://www.readbyqxmd.com/read/29131686/the-estimation-of-the-economic-burden-of-measles-in-terms-of-direct-and-indirect-costs-per-case
#1
Viera Svihrova, Maria Szilagyiova, Iveta Waczulikova, Elena Novakova, Henrieta Hudeckova
No abstract text is available yet for this article.
November 13, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/29129120/successful-treatment-of-hiv-hcv-coinfected-patients-in-the-era-of-direct-acting-antivirals-is-advanced-liver-disease-still-a-limiting-factor
#2
Jose Armando Gonzales Zamora
No abstract text is available yet for this article.
November 12, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/29125008/does-more-favourable-handling-of-the-cerebrospinal-fluid-increase-the-diagnostic-sensitivity-of-borrelia-burgdorferi-sensu-lato-specific-pcr-in-lyme-neuroborreliosis
#3
Kristine J N Forselv, Åslaug R Lorentzen, Unn Ljøstad, Åse Mygland, Randi Eikeland, Vivian Kjelland, Sølvi Noraas, Hanne Quarsten
BACKGROUND: Tests for direct detection of Borrelia burgdorferi sensu lato (Bb) in Lyme neuroborreliosis (LNB) are needed. Detection of Bb DNA using PCR is promising, but clinical utility is hampered by low diagnostic sensitivity. We aimed to examine whether diagnostic sensitivity can be improved by the use of larger cerebrospinal fluid (CSF) volumes and faster handling of samples. METHODS: Patients who underwent CSF examination for LNB were included. We collected two millilitres of CSF for PCR analysis, extracted DNA from the pellets within 24 h and analysed the eluate by two real-time PCR protocols (16S rRNA and OspA)...
November 10, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/29119851/clinical-characteristics-of-children-infected-with-enterovirus-d68-in-an-outpatient-clinic-and-the-association-with-bronchial-asthma
#4
Tsutomu Itagaki, Yoko Aoki, Yohei Matoba, Shizuka Tanaka, Tatsuya Ikeda, Katsumi Mizuta, Yoko Matsuzaki
BACKGROUND: All reports of increases in severe respiratory disease associated with human enterovirus D68 (EV-D68) are from hospital settings. However, there are few reports describing clinical characteristics in less severely affected populations. METHODS: We conducted a retrospective observational study from January 2010 to December 2015 in Yamagata, Japan. Using regional passive surveillance, 5794 respiratory specimens were collected from children who initially presented to an outpatient clinic with acute respiratory symptoms...
November 9, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/29119848/management-of-community-acquired-pneumonia-in-immunocompetent-adults-updated-swedish-guidelines-2017
#5
Simon Athlin, Christer Lidman, Anders Lundqvist, Pontus Naucler, Anna C Nilsson, Carl Spindler, Kristoffer Strålin, Jonas Hedlund
Based on expert group work, Swedish recommendations for the management of community-acquired pneumonia in adults are here updated. The management of sepsis-induced hypotension is addressed in detail, including monitoring and parenteral therapy. The importance of respiratory support in cases of acute respiratory failure is emphasized. Treatment with high-flow oxygen and non-invasive ventilation is recommended. The use of statins or steroids in general therapy is not found to be fully supported by evidence. In the management of pleural infection, new data show favourable effects of tissue plasminogen activator and deoxyribonuclease installation...
November 9, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/29105600/microbiology-in-burns-patients-with-blood-stream-infections-trends-over-time-and-during-the-course-of-hospitalization
#6
Dolores Sousa, Alejandra Ceniceros, Rita Galeiras, Sonia Pértega-Díaz, José-María Gutiérrez-Urbón, María Rodríguez-Mayo, Eugenia López-Suso, Mónica Mourelo-Fariña, Pedro Llinares
BACKGROUND: Bloodstream infections (BSI) are a major cause of mortality in burns patients. Knowledge of the microbiology is crucial to direct empirical therapy. We sought to determine the causative microorganisms and antibiotic resistance in burns patients with BSI. METHODS: All consecutive BSI episodes in a tertiary hospital burns unit from 2000 to 2014 were included. The following three subperiods were compared: 2000-2004, 2005-2009 and 2010-2014. Changes in BSI occurring during early and late hospitalization periods were evaluated...
November 6, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/29105519/staphylococcus-aureus-bacteraemia-and-endocarditis-epidemiology-and-outcome-a-review
#7
Hilmir Asgeirsson, Anders Thalme, Ola Weiland
PURPOSE: To review the epidemiology of Staphylococcus aureus bacteraemia (SAB) and endocarditis (SAE), and discuss the short- and long-term outcome.  Materials and methods: A literature review of the epidemiology of SAB and SAE. RESULTS: The reported incidence of SAB in Western countries is 16-41/100,000 person-years. Increasing incidence has been observed in many regions, in Iceland by 27% during 1995-2008. The increase is believed to depend on changes in population risk factors and possibly better and more frequent utilization of diagnostic procedures...
November 6, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/29087731/antifungal-prophylaxis-with-fluconazole-in-allogeneic-stem-cell-transplantation-recipients-who-had-prior-invasive-aspergillosis-with-subsequent-complete-resolution-by-computed-tomography
#8
Yu Akahoshi, Shun-Ichi Kimura, Ayumi Gomyo, Jin Hayakawa, Masaharu Tamaki, Naonori Harada, Machiko Kusuda, Kazuaki Kameda, Tomotaka Ugai, Hidenori Wada, Yuko Ishihara, Koji Kawamura, Kana Sakamoto, Miki Sato, Kiriko Terasako-Saito, Misato Kikuchi, Hideki Nakasone, Shinichi Kako, Yoshinobu Kanda
BACKGROUND: Consensus has yet to be reached regarding secondary prophylaxis in allogeneic hematopoietic stem cell transplantation (HSCT) with a complete resolution of invasive aspergillosis (IA) confirmed by chest computed tomography (CT). METHODS: We retrospectively evaluated the feasibility of antifungal prophylaxis with fluconazole in allogeneic HSCT recipients who had previously developed IA which showed complete resolution as confirmed by chest CT before HSCT...
October 31, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/29086602/the-use-of-cefepime-as-a-carbapenem-sparing-antibiotic-for-treating-uncomplicated-acute-pyelonephritis-caused-by-extended-spectrum-%C3%AE-lactamase-producing-escherichia-coli
#9
Jin Woong Suh, Kyung Sook Yang, Sun Bean Kim, Jong Hun Kim, Jang Wook Sohn, Min Ja Kim, Young Kyung Yoon
No abstract text is available yet for this article.
October 31, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/29078729/virulence-genes-flic-toxa-and-phzs-are-common-among-pseudomonas-aeruginosa-isolates-from-diabetic-foot-infections
#10
Bulent M Ertugrul, Erman Oryasin, Benjamin A Lipsky, Ayşe Willke, Bulent Bozdogan
BACKGROUND: Outcomes of antibiotic treatment of diabetic foot infections (DFIs) may depend not only on the antimicrobial susceptibility of the aetiologic agents, but also their ability to produce virulence factors. This study aimed to use polymerase chain reaction (PCR) with specific primers to investigate the presence of virulence genes among isolates of Pseudomonas aeruginosa isolates cultured from specimens from diabetic foot and other infections. METHODS: We examined 63 P...
October 27, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/29070003/pitfalls-in-studies-of-eosinopenia-and-neutrophil-to-lymphocyte-count-ratio
#11
Stamatis Karakonstantis, Dimitra Kalemaki, Emmanouil Tzagkarakis, Charalampos Lydakis
There is a number of publications evaluating the eosinophil count and the neutrophil-to-lymphocyte count ratio for diagnosis, prognosis or monitoring of patients. Of special interest is the use of these parameters for discrimination between the different causes of fever (e.g. bacterial versus viral vs. non-infectious causes of fever) and for monitoring the efficacy of therapy and predict the course of the patient. However, pitfalls in previous study designs prevent applicability to clinical practice. Here, we provide a short review of the relevant literature and summarize important factors that should be taken into account when designing studies, with special attention to the selection of a proper and clinically meaningful study population and the effects of the stress response and of corticosteroids...
October 26, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/29069970/first-report-of-oxa-48-producing-escherichia-coli-in-croatia-and-confirmed-intergenic-transfer-of-a-plasmid-carrying-blaoxa-48-from-klebsiella-pneumoniae
#12
Zrinka Bošnjak, Monika A Chlebowicz, Ivana Mareković, Violeta Rezo Vranješ, John W Rossen, Ana Budimir
No abstract text is available yet for this article.
October 26, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/29069962/limitations-of-quantiferon-tb-gold-assay-for-screening-of-psoriasis-patients-prior-to-anti-tumour-necrotic-factor-treatment
#13
Alessandra Bua, Stefania Zanetti, Maria Francesca Peigottu, Maria Antonetta Montesu, Paola Molicotti
No abstract text is available yet for this article.
October 26, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/29037090/prevention-and-the-state-of-knowledge-of-tick-borne-diseases-among-orienteers-in-poland
#14
Piotr Cych, Dorota Kiewra, Anna Szczepańska
No abstract text is available yet for this article.
October 16, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/29029581/prevalence-of-urinary-tract-infections-mimicking-respiratory-infections-and-risk-factors-associated
#15
Kalid Bouaghroum, Pierre-Luc Genillier, Dominique Neri, Djamel Lameche, Matteo Vassallo
No abstract text is available yet for this article.
October 13, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/29020844/nucleoside-nucleotide-analogues-in-the-treatment-of-chronic-hepatitis-b-infection-during-pregnancy-a-systematic-review
#16
Soheil Tavakolpour, Mohammad Darvishi, Hajar Sadat Mirsafaei, Mojtaba Ghasemiadl
BACKGROUND: Women of childbearing age who have developed chronic hepatitis B (CHB) infection, especially HBeAg-positive highly viraemic pregnant women, are largely responsible for the familial transmission of the infection. Therefore, choosing the most effective and safest antiviral medications to manage pregnant CHB patients is of crucial importance. MATERIALS AND METHODS: The PubMed and Scopus databases were searched through September 2017, for all the journal articles possessing original results regarding treatment of CHB pregnant women with any nucleos(t)ide analogue (NA) therapies, including lamivudine (LAM), adefovir (ADV), entecavir (ETV), telbivudine (LdT), and tenofovir (TDF)...
October 11, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28988525/the-role-of-biofilm-forming-on-mortality-in-patients-with-candidemia-a-study-derived-from-real-world-data
#17
Carlo Tascini, Emanuela Sozio, Laura Corte, Francesco Sbrana, Claudio Scarparo, Andrea Ripoli, Giacomo Bertolino, Maria Merelli, Enrico Tagliaferri, Antonio Corcione, Matteo Bassetti, Gianluigi Cardinali, Francesco Menichetti
BACKGROUND: Evaluation of the role on patient mortality exerted by biofilm forming (BF) Candida strains, by using predictive clinical data. METHODS: Eighty-nine strains isolated from Candida bloodstream infection, occurring in two Italian University Hospitals, were employed in this study. A random forest (RF) model was built with a procedure of iterative selection of the risk factors potentially able to predict the probability of death. The similarity between patient conditions and Bayesian clustering was calculated in order to evaluate the role of predictors in the stratification of the death risk...
October 9, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28980501/correction-to-driessen-et%C3%A2-al-the-influence-of-a-change-in-septic-shock-definitions-on-intensive-care-epidemiology-and-outcome-comparison-of-sepsis-2-and-sepsis-3-definitions
#18
(no author information available yet)
No abstract text is available yet for this article.
October 5, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28958186/a-place-for-bordetella-pertussis-in-pcr-based-diagnosis-of-community-acquired-pneumonia
#19
Bruno A López Luis, Ma De Lourdes Guerrero Almeida, Guillermo M Ruiz-Palacios
No abstract text is available yet for this article.
September 28, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28950786/the-influence-of-a-change-in-septic-shock-definitions-on-intensive-care-epidemiology-and-outcome-comparison-of-sepsis-2-and-sepsis-3-definitions
#20
Rob G H Driessen, Marcel C G van de Poll, Marianne F Mol, Walther N K A van Mook, Ronny M Schnabel
BACKGROUND: Clear definitions for septic shock assist clinicians regarding recognition, treatment and standardized reporting of characteristics and outcome of this entity. Sepsis-3 definition of septic shock incorporates a new criterion, a lactate level >2 mmol/L. Differences in epidemiology and outcome of septic shock based upon both definitions were studied in an intensive care (ICU) population of septic patients. METHODS: We analyzed a prospectively collected cohort of data in the ICU of the Maastricht University Medical Centre...
September 26, 2017: Infectious Diseases
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