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Infectious Diseases

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https://www.readbyqxmd.com/read/28095723/increased-long-term-mortality-after-survival-of-invasive-pneumococcal-disease-a-population-based-study
#1
Hans Kristian Floeystad, Are Holm, Leiv Sandvik, Didrik Frimann Vestrheim, Bjorn Brandsaeter, Dag Berild
OBJECTIVES: We studied if patients surviving hospitalization for invasive pneumococcal disease (IPD) have an increased long-term mortality. METHODS: In this population-based case-control study, we assessed adults discharged from Aker University Hospital in Oslo, Norway, from 1993 to 2008 after surviving IPD. Mortality among the study population was compared to the general Norwegian population using standardized mortality ratios (SMR). Median follow-up time was 7...
January 17, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28092214/treatment-of-delta-hepatitis-today-and-in-the-future-a-review
#2
Ibrahim Halil Bahcecioglu, Abdurrahman Sahin
Hepatitis delta virus (HDV) is a defective satellite virus and propagates in the presence of Hepatitis B virus (HBV) surface antigen (HBsAg). Approximately 5% of the people who infected with HBV are also infected with HDV. Chronic hepatitis caused by delta is the most severe form of chronic viral hepatitis including accelerated fibrosis, liver decompensation and development of hepatocellular carcinoma. Interferon-based therapies still remain the only treatment option of the hepatitis delta. The beneficiary effects of the interferon-based therapies, however, stop frequently with termination of the given therapy and relapse rate is very high...
January 16, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28092204/impact-of-combination-therapy-and-early-de-escalation-on-outcome-of-ventilator-associated-pneumonia-caused-by-pseudomonas-aeruginosa
#3
Laurène Deconinck, Agnès Meybeck, Pierre Patoz, Nicolas Van Grunderbeeck, Nicolas Boussekey, Arnaud Chiche, Pierre-Yves Delannoy, Hugues Georges, Olivier Leroy
BACKGROUND: Pseudomonas aeruginosa is a common cause of ventilator-associated pneumonia (VAP). Guidelines recommend dual coverage of P. aeruginosa, but the beneficial effect of combination therapy is controversial. We described antibiotic prescriptions and evaluated the clinical impact of initial combination antibiotic therapy and de-escalation strategy in patients with VAP caused by P. aeruginosa. METHODS: Between 1994 and 2014, all 100 patients with VAP caused by P...
January 16, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28077007/accurate-and-fast-urinalysis-in-febrile-patients-by-flow-cytometry
#4
Foppie J de Boer, Elske Gieteling, Heidi van Egmond-Kreileman, Bijan Moshaver, Sjef J C M van der Leur, Coen A Stegeman, Paul H P Groeneveld
BACKGROUND: The urine culture is worldwide accepted as the gold standard in diagnosing urinary tract infections, but is time consuming and costly, other methods are fast but moderately reliable. We investigated whether counting the number of bacteria by flow cytometry could be a fast and accurate method to analyze urine samples in febrile patients at the emergency department (ED). METHODS: Urine samples were obtained from 140 febrile patients at the ED. Urinalysis was performed according to standard procedures...
January 11, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28077005/corrigendum
#5
(no author information available yet)
No abstract text is available yet for this article.
January 11, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28071193/screening-of-esbl-producing-enterobacteriacae-concomitant-with-low-degree-of-transmission-in-intensive-care-and-bone-marrow-transplant-units
#6
Giuseppe Valenza, Monika Schulze, Petra Friedrich, Wulf Schneider-Brachert, Thomas Holzmann, Silke Nickel, Verena Lehner-Reindl, Christiane Höller
BACKGROUND: Extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E) are spreading worldwide in both hospital and community settings. In this study, the molecular epidemiology and the transmission modalities of ESBL-E in intensive care- and bone marrow transplant were investigated. METHODS: All patients included in this study were screened for presence of ESBL-E on admission and weekly. Relevant β-lactamase genes were identified by PCR and sequencing...
January 10, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28067093/rotavirus-epidemiology-5-6-years-after-universal-rotavirus-vaccination-persistent-rotavirus-activity-in-older-children-and-elderly
#7
Jukka Markkula, Maria Hemming-Harlo, Marjo T Salminen, Carita Savolainen-Kopra, Jaana Pirhonen, Haider Al-Hello, Timo Vesikari
BACKGROUND: Rotavirus (RV) vaccination using RotaTeq(®) vaccine exclusively was introduced into Finnish National Immunization Program (NIP) in 2009, and soon reached high (≥90%) coverage. Since mid-2013, all stool samples from laboratory diagnosed cases of RV gastroenteritis in the entire country have been typed. METHODS: 364 RV positive stool samples collected from clinical laboratories over a 2-year period were G- and P-typed using RT-PCR, and the results were confirmed by sequencing...
January 9, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28049383/a-lyme-borreliosis-diagnosis-probability-score-no-relation-with-antibiotic-treatment-response
#8
Violeta T Briciu, Mirela Flonta, Daniel Leucuţa, Dumitru Cârstina, Doina F Ţăţulescu, Mihaela Lupşe
OBJECTIVES: (1) To describe epidemiological and clinical data of patients that present with the suspicion of Lyme borreliosis (LB); (2) to evaluate a previous published score that classifies patients on the probability of having LB, following-up patients' clinical outcome after antibiotherapy. METHODS: Inclusion criteria: patients with clinical manifestations compatible with LB and Borrelia (B.) burgdorferi positive serology, hospitalized in a Romanian hospital between January 2011 and October 2012...
January 3, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28049382/use-of-intracranial-pressure-monitoring-in-bacterial-meningitis-a-10-year-follow-up-on-outcome-and-intracranial-pressure-versus-head-ct-scans
#9
Lykke Larsen, Frantz R Poulsen, Troels H Nielsen, Carl-Henrik Nordström, Mette K Schulz, Åse B Andersen
BACKGROUND: The aim of this study was to evaluate the clinical outcome of patients with severe bacterial meningitis where intracranial pressure (ICP) monitoring has been performed. METHODS: A retrospective observational study including patients admitted 1st(.) January 2005 to 31st(.) December 2014. Thirty nine patients age 18-89 years were included. All the patients received intensive care with mechanical ventilation, ICP monitoring, sedation, antibiotics and corticosteroids according to current guidelines...
January 3, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28049381/kidney-disease-in-puumala-hantavirus-infection
#10
Jukka Mustonen, Tuula Outinen, Outi Laine, Ilkka Pörsti, Antti Vaheri, Satu Mäkelä
Acute kidney injury (AKI) remains a predominant clinical expression of nephropathia epidemica (NE). Its pathogenesis is not yet fully understood. Here, we describe the tissue injury comprehensively and present new data aimed to characterize the injury and explain its pathophysiology. When compared to tubulointerstitial nephritis of a wide variety of other aetiologies, a high degree of proteinuria is a distinguished trait of NE, a finding that is also helpful in the clinical suspicion of the disease. Recently, novel biomarkers for the prediction of severe AKI, including neutrophil gelatinase-associated lipocalin (NGAL), have been identified and ultrastructural tissue changes have been more accurately described...
January 3, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28049378/isolation-of-escherichia-coli-st131-producing-kpc-2-in-bulgaria
#11
Rumyana Markovska, Temenuga Stoeva, Lyudmila Boyanova, Petya Stankova, Daniela Pencheva, Radka Kaneva, Vanyo Mitev, Ivan Mitov
No abstract text is available yet for this article.
January 3, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28024452/positive-predictive-value-of-elispot-in-bal-and-pleural-fluid-from-patients-with-suspected-pulmonary-tuberculosis
#12
Regina W Hofland, Steven F T Thijsen, Anne S R van Lindert, Wiel C M de Lange, Tamara van Gorkom, Ingeborg van der Tweel, Jan-Willem J Lammers, Aik W J Bossink
BACKGROUND: The aim of this study was to evaluate the positive predictive value (PPV) of ELISpot in bronchoalveolar lavage (BAL) and pleural fluid for the diagnosis of active tuberculosis (TB) in real-life clinical practice, together with the added value of a cut-off >1.0 for the ratio between the extra-sanguineous and systemic interferon-gamma responses in positive samples. METHODS: A retrospective, single-centre study was performed. Patients with positive ELISpot in BAL and pleural fluid were included...
December 26, 2016: Infectious Diseases
https://www.readbyqxmd.com/read/27973976/where-to-look-for-the-scabies-mite
#13
Stefano Veraldi, Luigi Esposito, Paolo Pontini, Gianluca Nazzaro, Rossana Schianchi
No abstract text is available yet for this article.
December 15, 2016: Infectious Diseases
https://www.readbyqxmd.com/read/27973972/erratum
#14
(no author information available yet)
No abstract text is available yet for this article.
December 15, 2016: Infectious Diseases
https://www.readbyqxmd.com/read/27911152/non-tuberculous-mycobacterial-bloodstream-infections-in-patients-with-indwelling-vascular-catheters-the-role-of-sickle-cell-anaemia
#15
Babatunde Edun, Ansal Shah, Martin Durkin, Melanie Whitmire, Shanetta Patterson Williams, Helmut Albrecht, Majdi Al-Hasan, Sharon Weissman
INTRODUCTION: Few studies have examined risk factors for nontuberculous mycobacteria (NTM) bloodstream infections (BSI) involving indwelling vascular catheters (IDVC). Sickle cell anaemia (HbSS/SC) is known to affect several aspects of the immune system leading to relative immune deficiency. The purpose of this retrospective nested case-control study was to determine if HbSS/SC is a risk factor for NTM BSI among individuals with IDVCs. METHODS: All NTM IDVC infections (cases) at two tertiary hospitals from 2008 to 2014 were reviewed...
December 2, 2016: Infectious Diseases
https://www.readbyqxmd.com/read/27911143/factors-predicting-life-threatening-infections-with-respiratory-syncytial-virus-in-adult-patients
#16
Se Yoon Park, Taeeun Kim, Young Rock Jang, Min-Chul Kim, Yong Pil Chong, Sang-Oh Lee, Sang-Ho Choi, Yang Soo Kim, Jun Hee Woo, Sung-Han Kim
BACKGROUND: Respiratory syncytial virus (RSV) is a significant cause of acute respiratory illness with a clinical spectrum ranging from self-limiting upper respiratory infection to severe lower respiratory infection in elderly persons as well as young children. However, there are limited data on risk factors for life-threatening infections that could guide the appropriate use of antiviral agents in adult patients with RSV. METHODS: We conducted a retrospective cohort study from October 2013 to September 2015...
December 2, 2016: Infectious Diseases
https://www.readbyqxmd.com/read/27900889/campylobacter-jejuni-strains-coresistant-to-tetracycline-and-ciprofloxacin-in-patients-with-gastroenteritis-in-croatia
#17
Merica Carev, Ana Kovačić, Anita Novak, Marija Tonkić, Ana Jerončić
BACKGROUND: Antibiotic-resistant Campylobacter jejuni strains are rapidly emerging worldwide. Here, we aimed to determine the antibiotic-resistance patterns and genetic structure of C. jejuni from stool samples of symptomatic patients in Dalmatia, the largest Croatian county. METHODS: In a population-based laboratory surveillance programme for campylobacteriosis in Dalmatia from May 2012 to May 2013, C. jejuni (n = 76) were collected from stool samples of all the patients hospitalized with gastroenteritis and matched positive outpatients (n = 77)...
November 30, 2016: Infectious Diseases
https://www.readbyqxmd.com/read/27900884/pericardial-effusion-as-a-paradoxical-reaction-on-treatment-with-second-line-antituberculous-agents
#18
Ira Shah, Sunayna Gurnani
No abstract text is available yet for this article.
November 30, 2016: Infectious Diseases
https://www.readbyqxmd.com/read/27887037/failure-of-crp-decline-within-three-days-of-hospitalization-is-associated-with-poor-prognosis-of-community-acquired-pneumonia
#19
Stine Bang Andersen, Gertrud Baunbæk Egelund, Andreas Vestergaard Jensen, Pelle Trier Petersen, Gernot Rohde, Pernille Ravn
BACKGROUND: C-reactive protein (CRP) is a well-known acute phase protein used to monitor the patient's response during treatment in infectious diseases. Mortality from Community-acquired Pneumonia (CAP) remains high, particularly in hospitalized patients. Better risk prediction during hospitalization could improve management and ultimately reduce mortality levels. The aim of this study was to evaluate CRP on the 3rd day (CRP3) of hospitalization as a predictor for 30 days mortality. METHODS: A retrospective multicentre cohort study of adult patients admitted with CAP at three Danish hospitals...
November 25, 2016: Infectious Diseases
https://www.readbyqxmd.com/read/27866452/efficacy-of-debridement-antibiotic-therapy-and-implant-retention-within-three-months-during-postoperative-instrumented-spine-infections
#20
Heidi Wille, Frédéric-Antoine Dauchy, Arnaud Desclaux, Hervé Dutronc, Marc-Olivier Vareil, Véronique Dubois, Jean-Marc Vital, Michel Dupon
BACKGROUND: Postoperative instrumented spine infection (PISI) is a severe complication of invasive spine procedures. METHODS: Retrospective study of patients treated for PISI between 1st January 2008 and 31st December 2012 in a French University Hospital. The objectives of this study were to describe the outcome of patients treated with debridement-irrigation, antibiotic therapy and implant retention (DAIR) within three months after the occurrence of PISI and to identify factors associated with relapse...
November 21, 2016: Infectious Diseases
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