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Lancet HIV

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https://www.readbyqxmd.com/read/27866873/factors-associated-with-the-uptake-of-and-adherence-to-hiv-pre-exposure-prophylaxis-in-people-who-have-injected-drugs-an-observational-open-label-extension-of-the-bangkok-tenofovir-study
#1
Michael Martin, Suphak Vanichseni, Pravan Suntharasamai, Udomsak Sangkum, Philip A Mock, Benjamaporn Chaipung, Dararat Worrajittanon, Manoj Leethochawalit, Sithisat Chiamwongpaet, Somyot Kittimunkong, Roman J Gvetadze, Janet M McNicholl, Lynn A Paxton, Marcel E Curlin, Timothy H Holtz, Taraz Samandari, Kachit Choopanya
BACKGROUND: Results of the randomised, double-blind, placebo-controlled Bangkok Tenofovir Study (BTS) showed that taking tenofovir daily as pre-exposure prophylaxis (PrEP) can reduce the risk of HIV infection by 49% in people who inject drugs. In an extension to the trial, participants were offered 1 year of open-label tenofovir. We aimed to examine the demographic characteristics, drug use, and risk behaviours associated with participants' uptake of and adherence to PrEP. METHODS: In this observational, open-label extension of the BTS (NCT00119106), non-pregnant, non-breastfeeding, HIV-negative BTS participants, all of whom were current or previous injecting drug users at the time of enrolment in the BTS, were offered daily oral tenofovir (300 mg) for 1 year at 17 Bangkok Metropolitan Administration drug-treatment clinics...
November 17, 2016: Lancet HIV
https://www.readbyqxmd.com/read/27866872/commitment-issues-prep-adherence-in-injecting-drug-users
#2
Kimberly Page, Oliver Bacon
No abstract text is available yet for this article.
November 17, 2016: Lancet HIV
https://www.readbyqxmd.com/read/27864001/actionable-adherence-monitoring-to-optimise-intervention
#3
Jessica E Haberer
No abstract text is available yet for this article.
November 15, 2016: Lancet HIV
https://www.readbyqxmd.com/read/27864000/timing-of-initiation-of-antiretroviral-therapy-and-adverse-pregnancy-outcomes-a-systematic-review-and-meta-analysis
#4
Olalekan A Uthman, Jean B Nachega, Jean Anderson, Steve Kanters, Edward J Mills, Françoise Renaud, Shaffiq Essajee, Meg C Doherty, Lynne M Mofenson
BACKGROUND: Although lifelong combination antiretroviral therapy (ART) is recommended for all individuals with HIV, few data exist for pregnancy outcomes associated with ART initiation before conception. We assessed adverse pregnancy outcomes associated with ART initiated before conception compared with that of ART started after conception. METHODS: We did a systematic review of studies from low-income, middle-income, and high-income countries by searching the Cochrane Central Register of Controlled Trials, Embase, LILACS, MEDLINE, Toxline, Web of Knowledge, and WHO Global Index Medicus and trials in progress (International Clinical Trials Registry Platform) for randomised trials, quasi-randomised trials, and prospective cohort studies done between Jan 1, 1980, and June 1, 2016, in which timing of ART initiation in pregnant women living with HIV was reported...
November 15, 2016: Lancet HIV
https://www.readbyqxmd.com/read/27863999/assessing-progress-with-hiv-incidence-in-national-cohorts
#5
Salim S Abdool Karim
No abstract text is available yet for this article.
November 15, 2016: Lancet HIV
https://www.readbyqxmd.com/read/27863998/swaziland-hiv-incidence-measurement-survey-shims-a-prospective-national-cohort-study
#6
Jessica Justman, Jason B Reed, George Bicego, Deborah Donnell, Keala Li, Naomi Bock, Alison Koler, Neena M Philip, Charmaine K Mlambo, Bharat S Parekh, Yen T Duong, Dennis L Ellenberger, Wafaa M El-Sadr, Rejoice Nkambule
BACKGROUND: Swaziland has the highest national HIV prevalence worldwide. The Swaziland HIV Incidence Measurement Survey (SHIMS) provides the first national HIV incidence estimate based on prospectively observed HIV seroconversions. METHODS: A two-stage survey sampling design was used to select a nationally representative sample of men and women aged 18-49 years from 14 891 households in 575 enumeration areas in Swaziland, who underwent household-based counselling and rapid HIV testing during 2011...
November 15, 2016: Lancet HIV
https://www.readbyqxmd.com/read/27863997/a-link-between-antiretrovirals-and-perinatal-outcomes
#7
Laurent Mandelbrot, Jeanne Sibiude
No abstract text is available yet for this article.
November 15, 2016: Lancet HIV
https://www.readbyqxmd.com/read/27863996/interventions-to-improve-adherence-to-antiretroviral-therapy-a-systematic-review-and-network-meta-analysis
#8
Steve Kanters, Jay J H Park, Keith Chan, Maria Eugenia Socias, Nathan Ford, Jamie I Forrest, Kristian Thorlund, Jean B Nachega, Edward J Mills
BACKGROUND: High adherence to antiretroviral therapy is crucial to the success of HIV treatment. We evaluated comparative effectiveness of adherence interventions with the aim of informing the WHO's global guidance on interventions to increase adherence. METHODS: For this systematic review and network meta-analysis, we searched for randomised controlled trials of interventions that aimed to improve adherence to antiretroviral therapy regimens in populations with HIV...
November 15, 2016: Lancet HIV
https://www.readbyqxmd.com/read/27815068/body-composition-and-metabolic-outcomes-after-96-weeks-of-treatment-with-ritonavir-boosted-lopinavir-plus-either-nucleoside-or-nucleotide-reverse-transcriptase-inhibitors-or-raltegravir-in-patients-with-hiv-with-virological-failure-of-a-standard-first-line
#9
Mark A Boyd, Janaki Amin, Patrick W G Mallon, Nagalingeswaran Kumarasamy, Johan Lombaard, Robin Wood, Ploenchan Chetchotisakd, Praphan Phanuphak, Lerato Mohapi, Iskandar Azwa, Waldo H Belloso, Jean-Michel Molina, Jennifer Hoy, Cecilia L Moore, Sean Emery, David A Cooper
BACKGROUND: Lipoatrophy is one of the most feared complications associated with the use of nucleoside or nucleotide reverse transcriptase inhibitors (N[t]RTIs). We aimed to assess soft-tissue changes in participants with HIV who had virological failure of a first-line antiretroviral (ART) regimen containing a non-nucleoside reverse transcriptase inhibitor plus two N(t)RTIs and were randomly assigned to receive a second-line regimen containing a boosted protease inhibitor given with either N(t)RTIs or raltegravir...
November 1, 2016: Lancet HIV
https://www.readbyqxmd.com/read/27815067/art-regimes-and-fat-the-healing-hand-wielding-the-sword
#10
Pere Domingo, Javier Espinet, Francesc Vidal
No abstract text is available yet for this article.
November 1, 2016: Lancet HIV
https://www.readbyqxmd.com/read/27771232/are-we-shifting-attrition-downstream-in-the-hiv-cascade
#11
Matthew P Fox
No abstract text is available yet for this article.
October 19, 2016: Lancet HIV
https://www.readbyqxmd.com/read/27765665/improved-labelling-of-antiretrovirals-for-paediatric-use
#12
David M Burger, Annemarie Mc van Rossum
No abstract text is available yet for this article.
October 17, 2016: Lancet HIV
https://www.readbyqxmd.com/read/27658881/cognitive-behavioural-therapy-for-adherence-and-depression-in-patients-with-hiv-a-three-arm-randomised-controlled-trial
#13
Steven A Safren, C Andres Bedoya, Conall O'Cleirigh, Katie B Biello, Megan M Pinkston, Michael D Stein, Lara Traeger, Erna Kojic, Gregory K Robbins, Jonathan A Lerner, Debra S Herman, Matthew J Mimiaga, Kenneth H Mayer
BACKGROUND: Depression is highly prevalent in people with HIV and has consistently been associated with poor antiretroviral therapy (ART) adherence. Integrating cognitive behavioural therapy (CBT) for depression with adherence counselling using the Life-Steps approach (CBT-AD) has an emerging evidence base. The aim of this study was to test the efficacy of CBT-AD. METHODS: In this three-arm randomised controlled trial in HIV-positive adults with depression, we compared CBT-AD with information and supportive psychotherapy plus adherence counselling using the Life-Steps approach (ISP-AD), and with enhanced treatment as usual (ETAU) including Life-Steps adherence counselling only...
September 19, 2016: Lancet HIV
https://www.readbyqxmd.com/read/27658862/cbt-for-depression-and-drug-adherence-in-hiv-care
#14
Dickens Akena, Hillary Kuteesa, Racheal Alinaitwe
No abstract text is available yet for this article.
September 19, 2016: Lancet HIV
https://www.readbyqxmd.com/read/27658865/when-is-a-prep-candidate-ready-for-phase-3
#15
Craig Hendrix
No abstract text is available yet for this article.
September 16, 2016: Lancet HIV
https://www.readbyqxmd.com/read/27658867/pretreatment-hiv-drug-resistance-in-mexico-and-its-impact-on-the-effectiveness-of-first-line-antiretroviral-therapy-a-nationally-representative-2015-who-survey
#16
Santiago Ávila-Ríos, Claudia García-Morales, Margarita Matías-Florentino, Karla A Romero-Mora, Daniela Tapia-Trejo, Verónica S Quiroz-Morales, Helena Reyes-Gopar, Hezhao Ji, Paul Sandstrom, Jesús Casillas-Rodríguez, Juan Sierra-Madero, Eddie A León-Juárez, Marisol Valenzuela-Lara, Carlos Magis-Rodríguez, Patricia Uribe-Zuñiga, Gustavo Reyes-Terán
BACKGROUND: WHO has developed a global HIV-drug resistance surveillance strategy, including assessment of pretreatment HIV-drug resistance. We aimed to do a nationally representative survey of pretreatment HIV-drug resistance in Mexico using WHO-recommended methods. METHODS: Among 161 Ministry of Health antiretroviral therapy (ART) clinics in Mexico, the largest, including 90% of ART initiators within the Ministry of Health (66 in total), were eligible for the survey...
September 14, 2016: Lancet HIV
https://www.readbyqxmd.com/read/27658866/next-generation-sequencing-and-hiv-drug-resistance-surveillance
#17
Raph L Hamers, Roger Paredes
No abstract text is available yet for this article.
September 14, 2016: Lancet HIV
https://www.readbyqxmd.com/read/27658868/first-line-integrase-inhibitors-for-hiv-prices-versus-benefits
#18
Anton L Pozniak, Andrew M Hill
No abstract text is available yet for this article.
September 6, 2016: Lancet HIV
https://www.readbyqxmd.com/read/27884374/obstacles-to-prescribers-initiation-early-antiretroviral-therapy-a-barrier-to-achieving-90-90-90-goals
#19
LETTER
Nicholas A Medland, Limin Mao, Levinia Crooks, John de Wit
No abstract text is available yet for this article.
December 2016: Lancet HIV
https://www.readbyqxmd.com/read/27884373/gbd-2015-and-hiv-estimates-from-the-optima-model-authors-reply
#20
LETTER
Haidong Wang, Christopher J L Murray
No abstract text is available yet for this article.
December 2016: Lancet HIV
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