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Frontiers in Nutrition

Lena Herden, Robert Weissert
Background: The literature concerning the effect of coffee and caffeine on Multiple Sclerosis (MS) with focus on fatigue is investigated in this review. Potentially clinically relevant effects were also assessed in studies concerning comparable neurodegenerative diseases, such as Parkinson's disease (PD) and amyotrophic lateral sclerosis (ALS). Since the existing studies obtained very inconclusive results, we systematically reviewed these studies to summarize the evidence on the possible effects of coffee and caffeine on those disease entities...
2018: Frontiers in Nutrition
Neil A Schwarz, Zachary J Blahnik, Srihari Prahadeeswaran, Sarah K McKinley-Barnard, Shelley L Holden, Andy Waldhelm
The purpose of the study was to determine if cycling exercise combined with (-)-epicatechin supplementation was more effective at increasing training adaptations than cycling combined with a placebo. Blood and muscle samples were obtained at rest before and after training to determine the effects of (-)-epicatechin supplementation on total serum antioxidant capacity, skeletal muscle mitochondrial protein content, and skeletal muscle myostatin gene expression. Participants ( n = 20) completed two testing sessions separated by 4 weeks of cycle training, with supplementation of 100 mg (200 mg total daily) of (-)-epicatechin or a placebo, twice daily...
2018: Frontiers in Nutrition
Heather D Gibbs, Juliana Camargo, Susana Patton, Jamie Zoellner, Yvonnes Chen, Ana Paula Cupertino, Susan Harvey, Byron Gajewski, Debra K Sullivan
Parental nutrition literacy (PNL) correlates positively with child diet quality, but interventions for improving PNL are lacking. "Nutricity" is a novel bilingual (English/Spanish) mobile tool designed by the research team to engage parents and young children to interact with nutrition information to make nutrition decisions. The purpose of this study was to inform a future intervention through (1) assessing parental likability of Nutricity, and (2) collecting perceptions of pediatric clinic personnel on the feasibility of introducing Nutricity in pediatric clinics...
2018: Frontiers in Nutrition
Ai Kimura, Taiki Sugimoto, Shumpei Niida, Kenji Toba, Takashi Sakurai
Background: Sarcopenia is frequently seen in patients with mild cognitive impairment (MCI) and early-stage Alzheimer's disease (AD). While appetite loss and physical inactivity, which are also frequently seen in dementia, appear to contribute to sarcopenia, to date, no study has investigated this association. Objective: The aim of this study was to examine factors associated with sarcopenia, including appetite and physical activity, in patients with MCI and early-stage AD. Methods: The study subjects comprised 205 outpatients (MCI, n = 151; early-stage AD, n = 54) who were being treated at the Memory Clinic, National Center for Geriatrics, and Gerontology and had a Mini-Mental State Examination (MMSE) score of 21 or higher...
2018: Frontiers in Nutrition
Yuanlong Pan, Gary Landsberg, Isabelle Mougeot, Stephanie Kelly, Hui Xu, Sandeep Bhatnagar, Cari L Gardner, Norton W Milgram
Cognitive dysfunction syndrome (CDS) is a common condition in senior dogs, which may be analogous to dementia such as Alzheimer's disease (AD) in people. In humans, AD has been associated with many risk factors such as reduced cerebral glucose metabolism, docosahexaenoic acid (DHA) deficiency, chronic oxidative stress, and chronic inflammation. By targeting some of these risk factors, we have developed two nutritional solutions (medium chain triglyceride, MCT and Brain Protection Blend, BPB) to enhance cognitive function and slow aging-induced cognitive decline...
2018: Frontiers in Nutrition
Nanami Sameshima Uto, Haruka Amitani, Yuta Atobe, Yoshihiro Sameshima, Mika Sakaki, Natasya Rokot, Koji Ataka, Marie Amitani, Akio Inui
Frailty and sarcopenia have recently gained considerable attention in terms of preventive care in Japan, which has an ever-increasing aging population. Sarcopenia is defined as atrophy of skeletal muscles caused by the age-related decrease in growth hormone/insulin-like growth factor and sex hormones. The Japanese Ministry of Health, Labor and Welfare reports that frailty can lead to impairment of both mental and physical functioning. Chronic diseases such as diabetes and dementia may underlie frailty. It is important to prevent progression of frailty and extend the healthy lifespan...
2018: Frontiers in Nutrition
Xavier Brenachot, Emmanuelle Nédélec, Selma Ben Fradj, Gaelle Boudry, Véronique Douard, Amélie Laderrière, Aleth Lemoine, Fabienne Liénard, Danaé Nuzzaci, Luc Pénicaud, Caroline Rigault, Alexandre Benani
High variability exists in individual susceptibility to develop overweight in an obesogenic environment and the biological underpinnings of this heterogeneity are poorly understood. In this brief report, we show in mice that the vulnerability to diet-induced obesity is associated with low level of polysialic acid-neural cell adhesion molecule (PSA-NCAM), a factor of neural plasticity, in the hypothalamus. As we previously shown that reduction of hypothalamic PSA-NCAM is sufficient to alter energy homeostasis and promote fat storage under hypercaloric pressure, inter-individual variability in hypothalamic PSA-NCAM might account for the vulnerability to diet-induced obesity...
2018: Frontiers in Nutrition
Clifton K Fagerquist, William J Zaragoza
We performed proteolytic surface-shaving with trypsin on three strains/sevovars of Salmonella enterica enterica (SEE): Newport, Kentucky, and Thompson. Surfaced-exposed proteins of live bacterial cells were digested for 15 min. A separate 20 h re-digestion was also performed on the supernatant of each shaving experiment to more completely digest protein fragments into detectable peptides for proteomic analysis by nano-liquid chromatography-electrospray ionization-Orbitrap mass spectrometry. Control samples (i...
2018: Frontiers in Nutrition
Dana Efrati Philip, Ghada Baransi, Danit R Shahar, Aron M Troen
Introduction: In many affluent countries, including Israel, networks of food banks and pantries have increasing responsibility to alleviate endemic poverty and food insecurity. While they may relieve acute hunger, their long-term influence on health and well-being is poorly understood. Methods: An exploratory cross-sectional telephone survey assessed both adequacy and quality of food aid provided via food pantries in the Leket Israel food bank network, in relation to recipients' dietary needs and health. The quality of food baskets and recipient diets were given a Healthy Portions Score (HPS) to measure compliance with Government guidelines for a "Basic Healthy Food Basket," and a Nutrient Density Score (NDS) to capture how well the food achieved the recommended dietary allowance (RDA) for vital macro and micronutrients...
2018: Frontiers in Nutrition
Karin Ried, Nikolaj Travica, Avni Sali
Background: Previous research suggests Kyolic-aged-garlic-extract to be effective in reducing blood pressure in a large proportion of hypertensive patients similar to first-line standard antihypertensive medication. High blood pressure has been linked to gut dysbiosis, with a significant decrease in microbial richness and diversity in hypertensives compared to normotensives. Furthermore, gut dysbiosis has been associated with increased inflammatory status and risk of cardiovascular events. Objective: To assess the effect of Kyolic aged GARlic extract on Gut microbiota, Inflammation, and Cardiovascular markers, including blood pressure, pulse wave velocity and arterial stiffness...
2018: Frontiers in Nutrition
Agnes Kilonzo-Nthenge, Siqin Liu, Sudheer Yannam, Ankit Patras
The contamination of fruits with human pathogens is a reoccurring concern in the fresh produce industry. Atmospheric cold plasma (ACP) is a potential alternate to customary approaches for non-thermal decontamination of foods. In this study, the efficacy of a dielectric barrier discharge ACP system against Salmonella ( Salmonella Typhimurium, ATCC 13311; Salmonella Choleraesuis, ATCC 10708) and Escherichia coli (ATCC 25922, ATCC 11775) was explored. For each bacteria, a two-strain mixture at 8 log10 CFU/ml was spot inoculated on the surface of Golden Delicious apples, air dried, and exposed to ACP at a fixed distance of 35 mm, input power of 200 W for 30, 60, 120, 180, and 240 s...
2018: Frontiers in Nutrition
Sweta Rai, Amarjeet Kaur, C S Chopra
The gluten protein of wheat triggers an immunological reaction in some gluten-sensitive people with HLA-DQ2/8 genotypes, which leads to Celiac disease (CD) with symptomatic damage in the small intestinal villi. Glutenin and gliadin are two major components of gluten that are essentially required for developing a strong protein network for providing desired viscoelasticity of dough. Many non-gluten cereals and starches (rice, corn, sorghum, millets, and potato/pea starch) and various gluten replacers (xanthan and guar gum) have been used for retaining the physical-sensorial properties of gluten-free, cereal-based products...
2018: Frontiers in Nutrition
Valérie Guillard, Sébastien Gaucel, Claudio Fornaciari, Hélène Angellier-Coussy, Patrice Buche, Nathalie Gontard
Packaging is an essential element of response to address key challenges of sustainable food consumption on the international scene, which is clearly about minimizing the environmental footprint of packed food. An innovative sustainable packaging aims to address food waste and loss reduction by preserving food quality, as well as food safety issues by preventing food-borne diseases and food chemical contamination. Moreover, it must address the long-term crucial issue of environmentally persistent plastic waste accumulation as well as the saving of oil and food material resources...
2018: Frontiers in Nutrition
Anna K Farmery, Gilly A Hendrie, Gabrielle O'Kane, Alexandra McManus, Bridget S Green
National dietary guidelines (DGs) consistently recommend consuming seafood for health benefits, however, the sustainability of increasing seafood consumption is often challenged. Seafood products vary in environmental performance as well as health benefits, yet there is no information integrating the health and ecological impacts of different seafood choices. The first step in optimising improved health and environmental outcomes is to examine more closely the types of seafood being consumed at population and individual levels, to develop the means to increase the intake of seafood that is optimal for human health and the environment...
2018: Frontiers in Nutrition
Enza Speranza, Iolanda Cioffi, Lidia Santarpia, Concetta Del Piano, Carmela De Caprio, Marianna Naccarato, Maurizio Marra, Emilia De Filippo, Franco Contaldo, Fabrizio Pasanisi
Nutritional disorders such as Anorexia Nervosa (AN) can shape the composition of gut microbiota and its metabolites such as short chain fatty acid (SCFA). This study aims to compare fecal SCFA along with dietary intake of women with restrictive AN (r-AN = 10) and those of sex-matched lean controls (C = 8). The main fecal short chain fatty acids (SCFA) were assessed by gas chromatography equipped with a flame ionization detector. All participants completed 7-day food record and underwent indirect calorimetry for measuring resting energy expenditure (REE)...
2018: Frontiers in Nutrition
Meghna Verma, Raquel Hontecillas, Nuria Tubau-Juni, Vida Abedi, Josep Bassaganya-Riera
No abstract text is available yet for this article.
2018: Frontiers in Nutrition
Andrew R Jagim, Richard A Stecker, Patrick S Harty, Jacob L Erickson, Chad M Kerksick
Creatine has been extensively researched and is well-supported as one of the most effective dietary supplements available. There is overwhelming support within the literature regarding the ability of creatine to augment performance following short term (5-7 days) and long-duration supplementation periods. There is also strong support for creatine regarding its safety profile and minimal risk for adverse events or any negative influence on markers of clinical health and safety. Recent research has also highlighted the ability of creatine to confer several health-related benefits in select clinical populations in addition to offering cognitive benefits...
2018: Frontiers in Nutrition
Lisa Striegel, Soraya Chebib, Caroline Dumler, Yuyun Lu, Dejian Huang, Michael Rychlik
Durian ( Durio zibethinus ) is a tropical fruit grown in Southeast Asia and highly appreciated by consumers throughout Asia. Folates are a group of vitamins and are essential nutrients for humans. Here we present the folate analysis of different durian cultivars as well as diverse durian products. An LC-MS/MS method and the application of a stable isotope dilution assay (SIDA) was used for quantitation of the folate vitamers 5-methyltetrahydrofolate, 5-formyltetrahydrofolate, 10-formylfolate, tetrahydrofolate, and pteroylmonoglutamic acid by using [13 C5 ]-labeled internal standards...
2018: Frontiers in Nutrition
Wakako Ikeda-Ohtsubo, Sylvia Brugman, Craig H Warden, Johanna M J Rebel, Gert Folkerts, Corné M J Pieterse
[This corrects the article DOI: 10.3389/fnut.2018.00090.].
2018: Frontiers in Nutrition
Shigekuni Hosogi, Masahiro Ohsawa, Ikuo Kato, Atsukazu Kuwahara, Toshio Inui, Akio Inui, Yoshinori Marunaka
Diabetes mellitus is a well-known common disease and one of the most serious social problems in the worldwide. Although various types of drugs are developed, the number of patients suffering from diabetes mellitus is still increasing. Ninjin'yoeito (NYT) is one of formulas used in Japanese traditional herbal medicines for improving various types of metabolic disorders. However, the effect of NYT on diabetes mellitus has not yet been investigated. In the present study, we tried to clarify the action of NYT on the serum glucose level in streptozotocin (STZ)-induced diabetic mice...
2018: Frontiers in Nutrition
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