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BMJ Open Diabetes Research & Care

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https://www.readbyqxmd.com/read/29018529/corrections-glucose-lowering-effect-of-whey-protein-depends-upon-clinical-characteristics-of-patients-with-type-2-diabetes
#1
(no author information available yet)
[This corrects the article DOI: 10.1136/bmjdrc-2017-000420.][This corrects the article DOI: 10.1136/bmjdrc-2017-000420.].
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28989726/carbohydrate-last-meal-pattern-lowers-postprandial-glucose-and-insulin-excursions-in-type-2-diabetes
#2
Alpana P Shukla, Jeselin Andono, Samir H Touhamy, Anthony Casper, Radu G Iliescu, Elizabeth Mauer, Yuan Shan Zhu, David S Ludwig, Louis J Aronne
BACKGROUND: There are limited data regarding the timing of carbohydrate ingestion during a meal and postprandial glucose regulation. METHODS: Sixteen subjects with type 2 diabetes mellitus (T2DM) consumed the same meal on 3 days in random order: carbohydrate first, followed 10 min later by protein and vegetables; protein and vegetables first, followed 10 min later by carbohydrate; or all components together. Blood was sampled for glucose, insulin, glucagon-like peptide-1 (GLP-1), and glucagon measurements at baseline (just before meal ingestion) and subsequently at 30 min intervals up to 180 min...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28948029/correction-anagliptin-ameliorates-albuminuria-and-urinary-liver-type-fatty-acid-binding-protein-excretion-in-patients-with-type-2-diabetes-with-nephropathy-in-a-glucose-lowering-independent-manner
#3
(no author information available yet)
[This corrects the article DOI: 10.1136/bmjdrc-2017-000391.][This corrects the article DOI: 10.1136/bmjdrc-2017-000391.].
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28948028/follow-up-after-gestational-diabetes-a-fixable-gap-in-women-s-preventive-healthcare
#4
Judith Apt Bernstein, Emily Quinn, Omid Ameli, Myrita Craig, Timothy Heeren, Aviva Lee-Parritz, Ronald Iverson, Brian Jack, Lois McCloskey
OBJECTIVE: Gestational diabetes mellitus (GDM) is a known harbinger of future type 2 diabetes mellitus (T2DM), hypertension, and cardiac disease. This population-based study was designed to identify gaps in follow-up care relevant to prevention of T2DM in a continuously insured sample of women diagnosed with GDM. RESEARCH DESIGN AND METHODS: We analyzed data spanning 2005-2015 from OptumLabs Data Warehouse, a comprehensive, longitudinal, real-world data asset with deidentified lives across claims and clinical information, to describe patterns of preventive care after GDM...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28948027/engagement-and-outcomes-in-a-digital-diabetes-prevention-program-3-year-update
#5
S Cameron Sepah, Luohua Jiang, Robert J Ellis, Kelly McDermott, Anne L Peters
OBJECTIVE: Translations of the Diabetes Prevention Program (DPP) have proliferated in recent years, with increasing expansion to digital formats. Although these DPP translations have consistently shown favorable clinical outcomes, long-term data for digital formats are limited. This study's objective was to examine clinical outcomes up to 3 years post-baseline and the relationship between program engagement and clinical outcomes in a digital DPP. RESEARCH DESIGN AND METHODS: In a single-arm, non-randomized trial, 220 patients previously diagnosed with prediabetes were enrolled in the Omada Health Program, a commercially available, 16-week DPP-based weight loss intervention followed by an ongoing weight maintenance intervention...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28878943/obstructive-sleep-apnea-in-adults-with-type-1-and-type-2-diabetes-perspectives-from-a-quality-improvement-initiative-in-a-university-based-diabetes-center
#6
Simona Ioja, Eileen R Chasens, Jason Ng, Patrick J Strollo, Mary T Korytkowski
OBJECTIVE: Obstructive sleep apnea (OSA) and diabetes are frequent comorbid conditions. Screening for OSA in patients with diabetes is recommended but the frequency with which this is done in clinical practice is unknown. The objectives of this quality improvement initiative were to identify clinician and patient perceptions regarding OSA and to identify the prevalence of patients at high risk for OSA (HROSA). METHODS: A quality improvement initiative was conducted to query clinicians and patients attending a specialty diabetes clinic regarding attitudes and beliefs related to OSA...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28878942/medication-adherence-and-glycemic-control-among-newly-diagnosed-diabetes-patients
#7
Lee-Kai Lin, Yan Sun, Bee Hoon Heng, Daniel Ek Kwang Chew, Phui-Nah Chong
BACKGROUND: Poor medication adherence can have negative consequences for the patients, the provider, the physician, and the sustainability of the healthcare system. To our knowledge, the association between medication adherence and glycemic control among newly diagnosed diabetes patients has not been studied. This study aims to bridge the gap. METHOD: This is a retrospective cohort study of 2463 patients managed in the National Healthcare Group in Singapore with newly diagnosed diabetes...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28878941/clinical-profiles-comorbidities-and-complications-of-type-2-diabetes-mellitus-in-patients-from-united-arab-emirates
#8
Herbert F Jelinek, Wael M Osman, Ahsan H Khandoker, Kinda Khalaf, Sungmun Lee, Wael Almahmeed, Habiba S Alsafar
OBJECTIVE: To assess clinical profiles of patients with type 2 diabetes in the United Arab Emirates (UAE), including patterns, frequencies, and risk factors of microvascular and macrovascular complications. RESEARCH DESIGN AND METHODS: Four hundred and ninety patients with type 2 diabetes were enrolled from two major hospitals in Abu Dhabi. The presence of microvascular and macrovascular complications was assessed using logistic regression, and demographic, clinical and laboratory data were collected...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28878940/ethnic-differences-in-early-glycemic-control-in-childhood-onset-type-1-diabetes
#9
Amal R Khanolkar, Rakesh Amin, David Taylor-Robinson, Russell M Viner, Justin Warner, Evelien F Gevers, Terence Stephenson
Some ethnic minorities with type 1 diabetes (T1D) have worse glycemic control (higher glycated hemoglobin (HbA1c)) and increased risk for vascular complications. There is limited evidence on the impact of ethnicity on early glycemic control when most patients experience transient remission postdiagnosis. We examined associations between ethnicity and longitudinal HbA1c trajectories during the first 6 months postdiagnosis in a multiethnic cohort in East London. RESEARCH DESIGN AND METHODS: Data on 443 (50% female) children <19 years of age, with T1D and attending one of three clinics in East London between January 2005 and December 2015 were included...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28878939/insulin-sensitive-and-insulin-resistant-obese-and-non-obese-phenotypes-role-in-prediction-of-incident-pre-diabetes-in-a-longitudinal-biracial-cohort
#10
Ibiye Owei, Nkiru Umekwe, Casey Provo, Jim Wan, Samuel Dagogo-Jack
OBJECTIVE: We measured insulin sensitivity with euglycemic clamp (Si-clamp) in initially normoglycemic African Americans (AA) and European Americans (EA), to probe the existence of subphenotypes of obesity and leanness, and their impact on incident dysglycemia during longitudinal follow-up. RESEARCH DESIGN AND METHODS: 320 healthy subjects (176 AA, 144 EA; mean age 44.2±10.6 years) underwent baseline assessments, including Si-clamp and homeostasis model of insulin resistance (HOMA-IR) and were stratified into: insulin-resistant obese (IRO) (body mass index (BMI) >30 kg/m(2), Si-clamp <0...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28878938/presentation-pathology-and-prognosis-of-renal-disease-in-type-2-diabetes
#11
Jasmine Tan, L Jonathan Zwi, John F Collins, Mark R Marshall, Tim Cundy
OBJECTIVE: Non-diabetic renal disease (NDRD) is common in patients with type 2 diabetes (T2D), but the relationship between its presentation and prognosis is unknown. RESEARCH DESIGN AND METHODS: In a retrospective cohort study, we compared renal and patient survival among 263 patients with T2D who had native renal biopsies between 2002 and 2008 from three Auckland hospitals in New Zealand. The presence of diabetic nephropathy (DN), NDRD or mixed (DN and NDRD) was determined from biopsy...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28878937/contrast-sensitivity-to-spatial-gratings-in-moderate-and-dim-light-conditions-in-patients-with-diabetes-in-the-absence-of-diabetic-retinopathy
#12
Sare Safi, Anoushiravan Rahimi, Afsaneh Raeesi, Hamid Safi, Mohammad Aghazadeh Amiri, Mojtaba Malek, Mehdi Yaseri, Mohammad Haeri, Frank A Middleton, Eduardo Solessio, Hamid Ahmadieh
OBJECTIVE: To evaluate the ability of contrast sensitivity (CS) to discriminate loss of visual function in diabetic subjects with no clinical signs of retinopathy relative to that of normal subjects. RESEARCH DESIGN AND METHODS: In this prospective cross-sectional study, we measured CS in 46 diabetic subjects with a mean age of 48±6 years, a best-corrected visual acuity of 20/20 and no signs of diabetic retinopathy. The CS in these subjects was compared with CS measurements in 46 normal control subjects at four spatial frequencies (3, 6, 12, 18 cycles per degree) under moderate (500 lux) and dim (less than 2 lux) background light conditions...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28878936/primary-care-physicians-utilization-of-type-2-diabetes-screening-guidelines-and-referrals-to-behavioral-interventions-a-survey-linked-retrospective-study
#13
Sandhya Mehta, Michelle Mocarski, Tami Wisniewski, Karin Gillespie, K M Venkat Narayan, Kathleen Lang
OBJECTIVE: To assess primary care physicians' (PCPs) knowledge of type 2 diabetes screening guidelines (American Diabetes Association (ADA) and 2008 US Preventive Services Task Force (USPSTF)), the alignment between their self-reported adherence and actual practice, and how often PCPs recommended diabetes prevention and self-management education programs (DPP/DSME). RESEARCH DESIGN AND METHODS: An online survey of PCPs to understand knowledge and adherence toward use of USPSTF/ADA guidelines and recommendation of DPP/DSME...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28878935/elevated-incidence-rates-of-diabetes-in-peru-report-from-perudiab-a-national-urban-population-based-longitudinal-study
#14
Segundo Nicolas Seclen, Moises Ernesto Rosas, Arturo Jaime Arias, Cecilia Alexandra Medina
OBJECTIVE: A recent report from a non-nationally representative, geographically diverse sample in four separate communities in Peru suggests an unusually high diabetes incidence. We aimed to estimate the national diabetes incidence rate using PERUDIAB, a probabilistic, national urban population-based longitudinal study. RESEARCH DESIGN AND METHODS: 662 subjects without diabetes, selected by multistage, cluster, random sampling of households, representing the 24 administrative and the 3 (coast, highlands and jungle) natural regions across the country, from both sexes, aged 25+ years at baseline, enrolled in 2010-2012, were followed for 3...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28878934/postauthorization-safety-study-of-the-dpp-4-inhibitor-saxagliptin-a-large-scale-multinational-family-of-cohort-studies-of-five-outcomes
#15
Vincent Lo Re, Dena M Carbonari, M Elle Saine, Craig W Newcomb, Jason A Roy, Qing Liu, Qufei Wu, Serena Cardillo, Kevin Haynes, Stephen E Kimmel, Peter P Reese, David J Margolis, Andrea J Apter, K Rajender Reddy, Sean Hennessy, Harshvinder Bhullar, Arlene M Gallagher, Daina B Esposito, Brian L Strom
OBJECTIVE: To evaluate the risk of serious adverse events among patients with type 2 diabetes mellitus initiating saxagliptin compared with oral antidiabetic drugs (OADs) in classes other than dipeptidyl peptidase-4 (DPP-4) inhibitors. RESEARCH DESIGN AND METHODS: Cohort studies using 2009-2014 data from two UK medical record data sources (Clinical Practice Research Datalink, The Health Improvement Network) and two USA claims-based data sources (HealthCore Integrated Research Database, Medicare)...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28878933/comparison-of-a-two-bag-system-versus-conventional-treatment-protocol-one-bag-system-in-the-management-of-diabetic-ketoacidosis
#16
Iqbal Munir, Ramiz Fargo, Roger Garrison, Almira Yang, Andy Cheng, Ilho Kang, Ali Motabar, Karen Xu, Lawrence K Loo, Daniel I Kim
OBJECTIVE: We compared the conventional 'one-bag protocol' of management of diabetic ketoacidosis (DKA) with the 'two-bag protocol' which utilizes two bags of fluids, one containing saline and supplemental electrolytes and the other containing the same solution with the addition of 10% dextrose. RESEARCH DESIGN AND METHODS: A retrospective chart review and analysis was done on adult patients admitted for DKA to the Riverside University Health System Medical Center from 2008 to 2015...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28878932/individuals-at-high-risk-for-type-2-diabetes-invited-to-a-lifestyle-program-characteristics-of-participants-versus-non-participants-the-hunt-study-and-24-month-follow-up-of-participants-the-vend-risk-study
#17
Ingrid Sørdal Følling, Bård Kulseng, Kristian Midthjell, Vegar Rangul, Anne-S Helvik
OBJECTIVE: Prevention of type 2 diabetes mellitus is possible through lifestyle programs, but the effect depends on the program's content, resources, and setting. Lifestyle programs are often confronted with high rates of non-participation and attrition. This study invited individuals at high risk for type 2 diabetes to a lifestyle program in the Norwegian primary healthcare setting. The aims were to investigate possible differences in characteristics between participants and non-participants and to study the effect of the lifestyle program at 24-month follow-up for participants...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28878931/comorbid-depression-and-risk-of-lower-extremity-amputation-in-people-with-diabetes-systematic-review-and-meta-analysis
#18
Sinéad M O'Neill, Zubair Kabir, Grace McNamara, Claire Mary Buckley
OBJECTIVE: To compare the risk of lower extremity amputation (LEA) in people with diabetes with and without comorbid depression. RESEARCH DESIGN AND METHODS: A systematic review of the published literature was conducted. Six databases were searched including PubMed, CINAHL, EMBASE, Medline, the Cochrane Library and PsycARTICLES from inception to 22 June 2016, using a detailed search strategy and cross-checking of reference lists for potentially eligible studies published in English...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28878930/non-adherence-to-eye-care-in-people-with-diabetes
#19
Ann P Murchison, Lisa Hark, Laura T Pizzi, Yang Dai, Eileen L Mayro, Philip P Storey, Benjamin E Leiby, Julia A Haller
OBJECTIVE: Evaluate individual factors that impact adherence to eye care follow-up in patients with diabetes. DESIGN AND METHODS: A 4-year retrospective chart review was conducted for 1968 patients with diabetes over age 40 from an urban academic center. Data collected included demographics, insurance, visual acuity, smoking status, medications, dates of dilated fundus examinations (DFE), and reported hemoglobin A1C and blood glucose levels. The primary outcome was timely DFE follow-up adherence following the initial eye exam visit...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28761664/glucose-lowering-effect-of-whey-protein-depends-upon-clinical-characteristics-of-patients-with-type-2-diabetes
#20
Rogelio U Almario, Wendy M Buchan, David M Rocke, Sidika E Karakas
OBJECTIVE: Whey protein (WP) intake has been shown to reduce postprandial glycemia. Majority of WP research in type 2 diabetes (T2DM) involved acute challenge or weight loss studies. It is not known if WP supplementation can provide sustained glucose lowering. Our goal was to investigate the effects of WP on glycemia comprehensively by using continuous glucose monitoring (CGM) while avoiding the confounding effects of variable food intake through controlled feeding. RESEARCH DESIGN AND METHODS: This double-blinded and placebo (PL)-controlled study included 22 patients with T2DM patients (11 male, 11 female; age 57...
2017: BMJ Open Diabetes Research & Care
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