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BMJ Open Diabetes Research & Care

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https://www.readbyqxmd.com/read/27843557/inclusion-of-walnut-in-the-diets-of-adults-at-risk-for-type-2-diabetes-and-their-dietary-pattern-changes-a-randomized-controlled-cross-over-trial
#1
Valentine Yanchou Njike, Niloufarsadat Yarandi, Paul Petraro, Rockiy G Ayettey, Judith A Treu, David L Katz
BACKGROUND: In our recently published study, including walnuts in the diets of adults with prediabetes led to overall improvement in diet quality. This report adds to those study findings by examining the food groups displaced during walnut inclusion in the diets of those adults with prediabetes. METHODS: Randomized, controlled, modified Latin square parallel design with 2 treatment arms. The 112 participants (31 men, 81 women) were randomly assigned to a diet with or without dietary counseling to regulate calorie intake in a 1:1 ratio...
2016: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/27843556/seasonality-of-gestational-diabetes-mellitus-a-south-australian-population-study
#2
Petra E Verburg, Graeme Tucker, Wendy Scheil, Jan Jaap H M Erwich, Gus A Dekker, Claire T Roberts
OBJECTIVE: To investigate whether there is a seasonal variation in the incidence of gestational diabetes mellitus (GDM). RESEARCH DESIGN AND METHODS: This retrospective cohort study of 60 306 eligible South Australian live-born singletons during 2007-2011 recorded in the South Australian Perinatal Statistics Collection (SAPSC) examined the incidence of GDM in relation to estimated date of conception (eDoC). Fourier series analysis was used to model seasonal trends...
2016: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/27843555/evaluation-of-vitamin-d-relationship-with-type-2-diabetes-and-systolic-blood-pressure
#3
Shivananda Bijoor Nayak, Terry Gavaskar Ramnanansingh
OBJECTIVE: To investigate whether relationships exist among vitamin D, type 2 diabetes mellitus (T2DM), and blood pressure in Trinidadian subjects with T2DM. RESEARCH DESIGN AND METHODS: This was a case-controlled study to determine if vitamin D levels were lower in patients with T2DM. After data analysis, an exploratory hypothesis of vitamin D relationship to systolic blood pressure (SBP) was developed. Plasma calcifediol (25(OH)D) concentrations were used as a measurement for vitamin D levels and were determined by ELISA...
2016: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/27843554/gene-expression-profile-of-whole-blood-cells-differs-in-pregnant-women-with-positive-screening-and-negative-diagnosis-for-gestational-diabetes
#4
Rafael B Gelaleti, Débora C Damasceno, Daisy M F Salvadori, Iracema M P Calderon, Roberto A A Costa, Fernanda Piculo, David C Martins, Marilza V C Rudge
OBJECTIVE: To evaluate the gene expression profile of whole blood cells in pregnant women without diabetes (with positive screening and negative diagnosis for gestational diabetes mellitus (GDM)) compared with pregnant women with negative screening for GDM. RESEARCH DESIGN AND METHODS: Pregnant women were recruited in the Diabetes Perinatal Research Centre-Botucatu Medical School-UNESP and Botucatuense Mercy Hospital (UNIMED). Distributed into 2 groups: control (n=8), women with negative screening and non-diabetic (ND, n=13), with positive screening and negative diagnosis of GDM...
2016: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/27843553/diabetes-as-an-increasingly-common-comorbidity-among-patient-hospitalizations-for-tuberculosis-in-the-usa
#5
Roula S Zahr, Ryan A Peterson, Linnea A Polgreen, Joseph E Cavanaugh, Douglas B Hornick, Kevin L Winthrop, Philip M Polgreen
OBJECTIVE: Diabetes is a risk factor for active tuberculosis (TB). The purpose of this paper was to estimate the risk of hospitalization for TB with and without a secondary diagnosis of diabetes in groups with different ethnic backgrounds. RESEARCH DESIGN AND METHODS: We used the Nationwide Inpatient Sample from 1998 to 2011, identifying all patients with a primary diagnosis of TB and/or a secondary diagnosis of diabetes (type 1 or type 2) or HIV. Next, we performed logistic regression to investigate the association of diabetes status, HIV status, and race (and the interaction of diabetes and race) with the risk of hospitalization with a primary diagnosis of TB...
2016: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/27843552/remission-of-pre-diabetes-to-normal-glucose-tolerance-in-obese-adults-with-high-protein-versus-high-carbohydrate-diet-randomized-control-trial
#6
Frankie B Stentz, Amy Brewer, Jim Wan, Channing Garber, Blake Daniels, Chris Sands, Abbas E Kitabchi
OBJECTIVE: Remission of pre-diabetes to normal is an important health concern which has had little success in the past. This study objective was to determine the effect on remission of pre-diabetes with a high protein (HP) versus high carbohydrate (HC) diet and effects on metabolic parameters, lean and fat body mass in prediabetic, obese subjects after 6 months of dietary intervention. RESEARCH DESIGN AND METHODS: We recruited and randomized 24 pre-diabetes women and men to either a HP (30% protein, 30% fat, 40% carbohydrate; n=12) or HC (15% protein, 30% fat, 55% carbohydrate; n=12) diet feeding study for 6 months in this randomized controlled trial...
2016: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/27843551/economic-aspects-in-the-management-of-diabetes-in-italy
#7
A Marcellusi, R Viti, P Sciattella, G Aimaretti, S De Cosmo, V Provenzano, G Tonolo, F S Mennini
BACKGROUND: Diabetes mellitus (DM) is a chronic-degenerative disease associated with a high risk of chronic complications and comorbidities. The aim of this study is to estimate the average annual cost incurred by the Italian National Health Service (NHS) for the treatment of DM stratified by patients' comorbidities. Moreover, the model estimates the economic impact of implementing good clinical practice for the management of patients with DM. METHODS: Data were extrapolated from administrative database of the Marche Region and specific inclusion and exclusion criteria were developed from a clinical board in order to estimate patients with DM only, DM+1, DM+2, DM+3 and DM+4 comorbidities (cardiovascular disease, neuropathy, nephropathy and retinopathy)...
2016: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/27752329/large-scale-survey-of-rates-of-achieving-targets-for-blood-glucose-blood-pressure-and-lipids-and-prevalence-of-complications-in-type-2-diabetes-jddm-40
#8
Hiroki Yokoyama, Mariko Oishi, Hiroshi Takamura, Katsuya Yamasaki, Shin-Ichiro Shirabe, Daigaku Uchida, Hidekatsu Sugimoto, Yoshio Kurihara, Shin-Ichi Araki, Hiroshi Maegawa
OBJECTIVE: The fact that population with type 2 diabetes mellitus and bodyweight of patients are increasing but diabetes care is improving makes it important to explore the up-to-date rates of achieving treatment targets and prevalence of complications. We investigated the prevalence of microvascular/macrovascular complications and rates of achieving treatment targets through a large-scale multicenter-based cohort. RESEARCH DESIGN AND METHODS: A cross-sectional nationwide survey was performed on 9956 subjects with type 2 diabetes mellitus who consecutively attended primary care clinics...
2016: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/27752328/correlation-of-global-risk-assessment-with-cardiovascular-complications-in-patients-with-diabetes-mellitus-living-in-puerto-rico
#9
Efraín Rodríguez-Vigil, Migdalia Rodríguez-Chacón, José J Ruiz Valcarcel
OBJECTIVE: The objective of this study was to assess the current relationship between certain demographics and chemical factors, and the risk of cardiovascular complications, within a Puerto Rican population with diabetes mellitus. RESEARCH DESIGN AND METHODS: A total of 2075 patients with diabetes mellitus were retrospectively evaluated to determine the influence of certain demographics and chemical variables on the appearance of cardiovascular complications. A group of demographic and laboratory variables were analyzed...
2016: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/27752327/multiple-complications-among-people-with-diabetes-from-finland-an-18-year-follow-up-in-1994-2011
#10
Erja Forssas, Martti Arffman, Kristiina Manderbacka, Ilmo Keskimäki, Iiris Ruuth, Reijo Sund
OBJECTIVE: In this study, we examined trends in severe diabetes-related complications (acute myocardial infarction, stroke, lower extremity amputation, and end-stage renal disease) and prevalence of multiple complications in a total population with diabetes in Finland during an 18-year period. RESEARCH DESIGN AND METHODS: The total population with diabetes aged 30 years or older in 1994-2011 was obtained from several Finnish health registers. Only the first episode of each end point was included in the analysis...
2016: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/27752326/structural-equation-model-for-estimating-risk-factors-in-type-2-diabetes-mellitus-in-a-middle-eastern-setting-evidence-from-the-steps-qatar
#11
Andres Roman-Urrestarazu, Faleh Mohamed Hussain Ali, Husein Reka, Matthew J Renwick, Gabriela D Roman, Elias Mossialos
AIMS: Understanding type 2 diabetes mellitus is critical for designing effective diabetes prevention policies in Qatar and the Middle East. METHODS: Using the Qatar 2012 WHO STEPwise approach to surveillance survey, a subsample of 1224 Qatari participants aged 18-64 years was selected. Subjects had their fasting blood glucose levels tested, had not been diagnosed with or treated for diabetes, had a fasting time >12 hours and were not pregnant. We applied a hypothesized structural equation model (SEM) to assess sociodemographic, behavioral, anthropometric and metabolic variables affecting persons with type 2 diabetes mellitus...
2016: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/27738514/association-between-liver-enzymes-and-incident-type-2-diabetes-in-singapore-chinese-men-and-women
#12
Ye-Li Wang, Woon-Puay Koh, Jian-Min Yuan, An Pan
AIMS: To assess the association between liver enzymes and the risk of type 2 diabetes (T2D) in a Chinese population. METHODS: A nested case-control study comprising 571 T2D cases and 571 matched controls was conducted within the Singapore Chinese Health Study. Alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), and lactate dehydrogenase (LDH) were quantified in baseline plasma collected from them, while γ-glutamyltransferase (GGT) was assayed among 255 T2D cases with baseline hemoglobin A1c <6...
2016: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/27738513/mixed-methods-study-of-engagement-in-behaviors-to-prevent-type-2-diabetes-among-employees-with-pre-diabetes
#13
Jeffrey T Kullgren, Megan Knaus, Kristi Rahrig Jenkins, Michele Heisler
BACKGROUND: Many employers use screenings to identify and recommend modification of employees' risk factors for type 2 diabetes, yet little is known about how often employees then engage in recommended behaviors and what factors influence engagement. We examined the frequency of, facilitators of, and barriers to engagement in recommended behaviors among employees found to have pre-diabetes during a workplace screening. METHODS: We surveyed 82 University of Michigan employees who were found to have pre-diabetes during a 2014 workplace screening and compared the characteristics of employees who 3 months later were and were not engaged in recommended behaviors...
2016: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/27651912/process-quality-of-diabetes-care-under-favorable-access-to-healthcare-a-2-year-longitudinal-study-using-claims-data-in-japan
#14
Hirokazu Tanaka, Jun Tomio, Takehiro Sugiyama, Yasuki Kobayashi
OBJECTIVE: To investigate the process quality of diabetes care provided to patients under universal health insurance coverage. RESEARCH DESIGN AND METHODS: Using claim data for 570 363 beneficiaries aged 20-69 years who were covered by Health Insurance Societies between April 2010 and March 2012, we identified patients with type 2 diabetes who made follow-up visits at least every 3 months in the first year (subject-identification year). We assessed patient adherence to follow-up visits in the second year (quality-reporting year), calculated the proportion of patients that completed routine examinations for glycemic control and complications, and evaluated associations between characteristics of patients and quality indicators using multivariable logistic regression models...
2016: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/27651911/weight-loss-efficacy-of-a-novel-mobile-diabetes-prevention-program-delivery-platform-with-human-coaching
#15
Andreas Michaelides, Christine Raby, Meghan Wood, Kit Farr, Tatiana Toro-Ramos
OBJECTIVE: To evaluate the weight loss efficacy of a novel mobile platform delivering the Diabetes Prevention Program. RESEARCH DESIGN AND METHODS: 43 overweight or obese adult participants with a diagnosis of prediabetes signed-up to receive a 24-week virtual Diabetes Prevention Program with human coaching, through a mobile platform. Weight loss and engagement were the main outcomes, evaluated by repeated measures analysis of variance, backward regression, and mediation regression...
2016: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/27651910/systemic-inflammatory-responses-in-patients-with-type-2-diabetes-with-chronic-periodontitis
#16
Ruben Mesia, Fatemeh Gholami, Hong Huang, Michael Clare-Salzler, Ikramuddin Aukhil, Shannon M Wallet, Luciana M Shaddox
OBJECTIVE: The objective of this case-control study was to quantify the immune responsiveness in individuals with type 2 diabetes (T2D) as compared with patients without diabetes (NT2D) diagnosed with periodontitis. RESEARCH DESIGN AND METHODS: Peripheral blood was collected from 20 patients with moderate-to-severe chronic periodontitis (10 T2D, 10 NT2D). Blood samples were stimulated with ultrapure Porphyromonas gingivalis and Escherichia coli lipopolysaccharide (LPS) for 24 hours...
2016: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/27648292/evaluation-of-statin-prescriptions-in-type-2-diabetes-india-heart-watch-2
#17
Rajeev Gupta, Sailesh Lodha, Krishna K Sharma, Surendra K Sharma, Sunil Gupta, Arthur J Asirvatham, Bhupendra N Mahanta, Anuj Maheshwari, Dinesh C Sharma, Anand S Meenawat, Raghubir S Khedar
BACKGROUND: Contemporary treatment guidelines advise statin use in all patients with diabetes for reducing coronary risk. Use of statins in patients with type 2 diabetes has not been reported from India. METHODS: We performed a multisite (n=9) registry-based study among internists (n=3), diabetologists (n=3), and endocrinologists (n=3) across India to determine prescriptions of statins in patients with type 2 diabetes. Demographic and clinical details were obtained and prescriptions were audited for various medications with a focus on statins...
2016: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/27648291/high-risk-glycated-hemoglobin-trajectories-established-by-mid-20s-findings-from-a-birth-cohort-study
#18
Dara M Shearer, W Murray Thomson, Jonathan M Broadbent, Rachael McLean, Richie Poulton, Jim Mann
OBJECTIVE: To describe the natural history of glycemia (as measured by glycated hemoglobin (HbA1c)) over 12 years using group-based trajectory modeling (GBTM), and to examine baseline predictors of trajectory. RESEARCH DESIGN AND METHODS: HbA1c data collected at ages 26, 32 and 38 in the long-running, prospective Dunedin Multidisciplinary Health and Development Study were used to assign study members (n=893) to trajectories applying GBTM. A generalization of the model allowed the statistical linking of baseline demographic, smoking and anthropometric characteristics to group membership probability...
2016: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/27648290/plasma-glucose-and-insulin-response-to-two-oral-nutrition-supplements-in-adults-with-type-2-diabetes-mellitus
#19
Maureen B Huhmann, Kristen N Smith, Sherwyn L Schwartz, Stacie K Haller, Sarah Irvin, Sarah S Cohen
OBJECTIVE: The purpose of this clinical trial was to compare the glucose usage of two oral nutritional supplement (ONS) products and to assess whether a diabetes-specific formulation provides improved glucose stabilization and management compared with a standard formula. RESEARCH DESIGN AND METHODS: A total of 12 subjects with type 2 diabetes (7 males and 5 females) completed a randomized, cross-over design trial. Each subject consumed isocaloric amounts of either the standard ONS or the diabetes-specific formula ONS on different dates, 1 week apart...
2016: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/27648289/parity-and-type-2-diabetes-mellitus-a-study-of-insulin-resistance-and-%C3%AE-cell-function-in-women-with-multiple-pregnancies
#20
Ditte Smed Iversen, Julie Støy, Ulla Kampmann, Thomas Schmidt Voss, Lene Ring Madsen, Niels Møller, Per Glud Ovesen
OBJECTIVE: Increasing parity may be a risk factor for the development of type 2 diabetes mellitus and the metabolic alterations during a normal pregnancy induces a prediabetic state; thus, multiple pregnancies may act as a risk factor for development of type 2 diabetes if these physiological alterations in glucose homeostasis are not reversed postpartum. We hypothesize that multiple pregnancies may lead to β-cell exhaustion and that the insulin resistance that occurs during pregnancy may persist after multiple births...
2016: BMJ Open Diabetes Research & Care
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