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Open Heart

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https://www.readbyqxmd.com/read/28123767/distinct-risk-factors-of-atrial-fibrillation-in-patients-with-and-without-coronary-artery-disease-a-cross-sectional-analysis-of-the-boreas-cag-registry-data
#1
Naoto Murakami, Masaya Tanno, Nobuaki Kokubu, Junichi Nishida, Nobutaka Nagano, Hirofumi Ohnishi, Hiroshi Akasaka, Takayuki Miki, Kazufumi Tsuchihashi, Tetsuji Miura
OBJECTIVE: Although risk factors of atrial fibrillation (AF) in the general population have been characterised, their impacts on patients with specific diseases are unclear. Our aim was to determine whether risk factors of AF are different in patients with and those without coronary artery disease (CAD). METHODS: We enrolled 1871 consecutive patients who underwent coronary angiography for evaluation of symptoms suggestive of CAD in the BOREAS-CAG Registry between August 2014 and January 2015...
2017: Open Heart
https://www.readbyqxmd.com/read/28123766/low-incidence-of-left-atrial-delayed-enhancement-with-mri-in-patients-with-af-a-single-centre-experience
#2
John P Bois, James Glockner, Phillip M Young, Thomas A Foley, Seth Sheldon, Darrell B Newman, Grace Lin, Douglas L Packer, Peter A Brady
BACKGROUND: Atrial fibrillation (AF) is the most common sustained atrial arrhythmia. One potential target for ablation is left atrial (LA) scar (LAS) regions that may be the substrate for re-entry within the atria, thereby sustaining AF. Identification of LAS through LA delayed gadolinium enhancement (LADE) with MRI has been proposed. OBJECTIVES: We sought to evaluate LADE in patients referred for catheter ablation of AF. METHODS: Prospective analysis was conducted of consecutive patients who underwent pulmonary vein antrum isolation (PVAI) ablation for AF at a single institution...
2017: Open Heart
https://www.readbyqxmd.com/read/28123765/right-heart-function-during-simulated-altitude-in-patients-with-pulmonary-arterial-hypertension
#3
Leigh M Seccombe, Vincent Chow, Wei Zhao, Edmund M T Lau, Peter G Rogers, Austin C C Ng, Elizabeth M Veitch, Matthew J Peters, Leonard Kritharides
OBJECTIVE: Patients with pulmonary arterial hypertension (PAH) are often recommended supplemental oxygen for altitude travel due to the possible deleterious effects of hypoxia on pulmonary haemodynamics and right heart function. This includes commercial aircraft travel; however, the direct effects and potential risks are unknown. METHODS: Doppler echocardiography and gas exchange measures were investigated in group 1 patients with PAH and healthy patients at rest breathing room air and while breathing 15...
2017: Open Heart
https://www.readbyqxmd.com/read/28123764/cardiac-mechanics-and-dysfunction-with-anthracyclines-in-the-community-results-from-the-predict-study
#4
Hari K Narayan, Wei Wei, Ziding Feng, Daniel Lenihan, Ted Plappert, Virginia Englefield, Michael Fisch, Bonnie Ky
BACKGROUND: Our objective was to determine the relevance of changes in myocardial mechanics in diagnosing and predicting cancer therapeutics-related cardiac dysfunction (CTRCD) in a community-based population treated with anthracyclines. METHODS: Quantitative measures of cardiac mechanics were derived from 493 echocardiograms in 165 participants enrolled in the PREDICT study (A Multicenter Study in Patients Undergoing AnthRacycline-Based Chemotherapy to Assess the Effectiveness of Using Biomarkers to Detect and Identify Cardiotoxicity and Describe Treatment)...
2017: Open Heart
https://www.readbyqxmd.com/read/28123763/does-cardiac-rehabilitation-meet-minimum-standards-an-observational-study-using-uk-national-audit
#5
Patrick Doherty, Ahmad Salman, Gill Furze, Hasnain M Dalal, Alexander Harrison
OBJECTIVE: To assess the extent by which programmes meet national minimum standards for the delivery of cardiac rehabilitation (CR) as part of the National Certification Programme for Cardiovascular Rehabilitation (NCP_CR). METHODS: The analysis used UK National Audit of Cardiac Rehabilitation (NACR) data extracted and validated for the period 2013-2014 set against six NCP_CR measures deemed as important for the delivery of high-quality CR programmes. Each programme that achieved a single minimum standard was given a score of 1...
2017: Open Heart
https://www.readbyqxmd.com/read/28123762/percutaneous-pfo-closure-for-cryptogenic-stroke-in-the-setting-of-a-systematic-cardiac-and-neurological-screening-and-a-standardised-follow-up-protocol
#6
Stéphane Noble, Robert F Bonvini, Fabio Rigamonti, Roman Sztajzel, Fabienne Perren, Philippe Meyer, Hajo Müller, Marco Roffi
BACKGROUND: There are no uniform workup and follow-up (FU) protocols for patients presenting with cryptogenic embolism (CE) who undergo percutaneous closure of a patent foramen ovale (PFO). METHODS: We prospectively performed a systematic cardiac and neurological FU protocol in all patients who underwent percutaneous PFO closure in order to assess the incidence of subsequent cardiac and neurological adverse events. All patients received dual antiplatelet therapy for 6 months and were systematically included in a 12-month standardised FU protocol including: clinical evaluation-transthoracic and transoesophageal echocardiography, 24-hour Holter monitoring and/or 1-week R-test, and transcranial Doppler...
2017: Open Heart
https://www.readbyqxmd.com/read/28123761/clinical-disease-presentation-and-ecg-characteristics-of-lmna-mutation-carriers
#7
Laura Ollila, Kjell Nikus, Miia Holmström, Mikko Jalanko, Raija Jurkko, Maija Kaartinen, Juha Koskenvuo, Johanna Kuusisto, Satu Kärkkäinen, Eeva Palojoki, Eeva Reissell, Päivi Piirilä, Tiina Heliö
OBJECTIVE: Mutations in the LMNA gene encoding lamins A and C of the nuclear lamina are a frequent cause of cardiomyopathy accounting for 5-8% of familial dilated cardiomyopathy (DCM). Our aim was to study disease onset, presentation and progression among LMNA mutation carriers. METHODS: Clinical follow-up data from 27 LMNA mutation carriers and 78 patients with idiopathic DCM without an LMNA mutation were collected. In addition, ECG data were collected and analysed systematically from 20 healthy controls...
2017: Open Heart
https://www.readbyqxmd.com/read/28123760/relationships-among-achieved-heart-rate-%C3%AE-blocker-dose-and-long-term-outcomes-in-patients-with-heart-failure-with-atrial-fibrillation
#8
Robert J H Miller, Jonathan G Howlett, Michael H Chiu, Danielle A Southern, Merril Knudtson, Stephen B Wilton
OBJECTIVE: Higher β-blocker dose and lower heart rate are associated with decreased mortality in patients with systolic heart failure (HF) and sinus rhythm. However, in the 30% of patients with HF with atrial fibrillation (AF), whether β-blocker dose or heart rate predict mortality is less clear. We assessed the association between β-blocker dose, heart rate and all-cause mortality in patients with HF and AF. METHODS: We performed a retrospective cohort study in 935 patients (60% men, mean age 74, 44...
2016: Open Heart
https://www.readbyqxmd.com/read/28123759/coexistence-of-abnormal-systolic-motion-of-mitral-valve-in-a-consecutive-group-of-324-adult-tetralogy-of-fallot-patients-assessed-with-echocardiography
#9
Anushree Agarwal, Ian S Harris, Vaikom S Mahadevan, Elyse Foster
BACKGROUND: The presence of mitral valve prolapse (MVP) in congenital heart disease (CHD) patients is not well described. Tetralogy of Fallot (TOF) is the most common cyanotic CHD associated with overall good long-term survival after palliation. Since MVP is more often identified in adults and TOF patients are now surviving longer, we thus sought to perform this cohort study with a case-control design to (1) determine the prevalence of MVP and systolic displacement of mitral leaflets (SDML) in adult TOF patients, and (2) describe their clinical and imaging characteristics...
2016: Open Heart
https://www.readbyqxmd.com/read/28123758/high-prevalence-of-modifiable-stroke-risk-factors-identified-in-a-pharmacy-based-screening-programme
#10
Roopinder K Sandhu, Lisa Dolovich, Bishoy Deif, Walid Barake, Gina Agarwal, Alex Grinvalds, Ting Lim, F Russell Quinn, David Gladstone, David Conen, Stuart J Connolly, Jeff S Healey
BACKGROUND: Population-based screening for atrial fibrillation (AF) is a promising public health strategy to prevent stroke. However, none of the published reports have evaluated comprehensive screening for additional stroke risk factors such as hypertension and diabetes in a pharmacy setting. METHODS: The Program for the Identification of 'Actionable' Atrial Fibrillation in the Pharmacy Setting (PIAAF-Pharmacy) screened individuals aged ≥65 years, attending community pharmacies in Canada, who were not receiving oral anticoagulation (OAC)...
2016: Open Heart
https://www.readbyqxmd.com/read/28123757/lower-coronary-plaque-burden-in-patients-with-hiv-presenting-with-acute-coronary-syndrome
#11
E J O'Dwyer, P Bhamra-Ariza, S Rao, S Emmanuel, A Carr, C J Holloway
OBJECTIVE: Treated HIV infection is associated with a higher incidence of coronary artery disease and myocardial infarction, although the mechanisms remain unclear. We sought to characterise the burden of coronary artery disease in men with HIV using retrospective data from invasive coronary angiograms in patients presenting with acute coronary syndrome (ACS). METHODS: Demographic and coronary angiographic data were obtained from 160 men with ST elevation myocardial infarction, non-STEMI or high-risk chest pain; 73 HIV-infected cases and 87 age-matched controls...
2016: Open Heart
https://www.readbyqxmd.com/read/28123756/analysis-of-mortality-trends-due-to-cardiovascular-diseases-in-panama-2001-2014
#12
María Carrión Donderis, Ilais Moreno Velásquez, Franz Castro, Julio Zúñiga, Beatriz Gómez, Jorge Motta
OBJECTIVE: Cardiovascular diseases (CVDs) are still the leading cause of death worldwide despite the recent decline in mortality rates attributable to CVD in Western Europe and the Americas. The aim of this study is to investigate mortality trends due to ischaemic heart disease (IHD) and stroke in Panama from 2001 to 2014, as well as the mortality differences by sex and age groups. METHODS: Data were obtained from the National Mortality Register. The International Classification of Diseases 10th revision codes (ICD-10) I20-I25 and I60-I69 were used for IHD and stroke, respectively...
2016: Open Heart
https://www.readbyqxmd.com/read/28123755/influence-of-case-definition-on-incidence-and-outcome-of-acute-coronary-syndromes
#13
Azam Torabi, John G F Cleland, Nasser Sherwi, Paul Atkin, Hossein Panahi, Eric Kilpatrick, Simon Thackray, Angela Hoye, Farqad Alamgir, Kevin Goode, Alan Rigby, Andrew L Clark
OBJECTIVE: Acute coronary syndromes (ACS) are common, but their incidence and outcome might depend greatly on how data are collected. We compared case ascertainment rates for ACS and myocardial infarction (MI) in a single institution using several different strategies. METHODS: The Hull and East Yorkshire Hospitals serve a population of ∼560 000. Patients admitted with ACS to cardiology or general medical wards were identified prospectively by trained nurses during 2005...
2016: Open Heart
https://www.readbyqxmd.com/read/28008358/impact-of-microvascular-obstruction-on-semiautomated-techniques-for-quantifying-acute-and-chronic-myocardial-infarction-by-cardiovascular-magnetic-resonance
#14
Heerajnarain Bulluck, Stefania Rosmini, Amna Abdel-Gadir, Anish N Bhuva, Thomas A Treibel, Marianna Fontana, Shane Weinmann, Alex Sirker, Anna S Herrey, Charlotte Manisty, James C Moon, Derek J Hausenloy
AIMS: The four most promising semiautomated techniques (5-SD, 6-SD, Otsu and the full width half maximum (FWHM)) were compared in paired acute and follow-up cardiovascular magnetic resonance (CMR), taking into account the impact of microvascular obstruction (MVO) and using automated extracellular volume fraction (ECV) maps for reference. Furthermore, their performances on the acute scan were compared against manual myocardial infarct (MI) size to predict adverse left ventricular (LV) remodelling (≥20% increase in end-diastolic volume)...
2016: Open Heart
https://www.readbyqxmd.com/read/28008357/bicuspid-aortic-valve-disease-systematic-review-and-meta-analysis-of-surgical-aortic-valve-repair
#15
Maximilian Salcher, Huseyin Naci, Sarah Pender, Titus Kuehne, Marcus Kelm
Aortic valve repair is still emerging, and its role in the treatment of bicuspid aortic valve disease (BAVD) is not yet fully understood. Our objective is to synthesise available evidence on outcomes after surgical aortic valve repair in patients with BAVD. We conducted a systematic review of clinical studies using prespecified methods for searching, identifying and selecting eligible studies in 4 databases, and synthesising results (PROSPERO 2014:CRD42014014415). 2 researchers independently reviewed full-text articles and extracted data...
2016: Open Heart
https://www.readbyqxmd.com/read/28008356/frailty-is-associated-with-delirium-and-mortality-after-transcatheter-aortic-valve-implantation
#16
Patricia Assmann, Peter Kievit, Kees van der Wulp, Michel Verkroost, Luc Noyez, Hans Bor, Yvonne Schoon
OBJECTIVE: We hypothesised that frailty assessment is of additional value to predict delirium and mortality after transcatheter aortic valve implantation (TAVI). METHODS: Observational study in 89 consecutive patients who underwent TAVI. Inclusion from November 2012 to February 2014, follow-up until April 2014. Measurement of the association of variables from frailty assessment and cardiological assessment with delirium and mortality after TAVI, respectively. RESULTS: Incidence of delirium after TAVI: 25/89 (28%)...
2016: Open Heart
https://www.readbyqxmd.com/read/28008355/distinguishing-between-those-dying-suddenly-or-not-suddenly-from-coronary-heart-disease-long-term-prospective-results-from-the-northwick-park-heart-study
#17
Tom Meade, Tim Clayton, Douglas Chamberlain
AIM: To establish whether ECG findings are associated with subsequent risk of sudden death from coronary heart disease (CHD). METHODS AND RESULTS: Potential risk factors for CHD were measured at entry to the first Northwick Park Heart Study of 2167 men. ECG findings were coded as high or low risk for CHD according to definitions in the Minnesota code. Sudden or non-sudden deaths were defined as occurring in less than or more than 24 hours, respectively. The only factor independently associated with sudden death among the 262 men dying of CHD was high-risk ECG...
2016: Open Heart
https://www.readbyqxmd.com/read/28008354/percutaneous-balloon-aortic-valvuloplasty-in-the-era-of-transcatheter-aortic-valve-implantation-a-narrative-review
#18
Thomas R Keeble, Arif Khokhar, Mohammed Majid Akhtar, Anthony Mathur, Roshan Weerackody, Simon Kennon
The role of percutaneous balloon aortic valvuloplasty (BAV) in the management of severe symptomatic aortic stenosis has come under the spotlight following the development of the transcatheter aortic valve implantation (TAVI) technique. Previous indications for BAV were limited to symptom palliation and as a bridge to definitive therapy for patients undergoing conventional surgical aortic valve replacement (AVR). In the TAVI era, BAV may also be undertaken to assess the 'therapeutic response' of a reduction in aortic gradient in borderline patients often with multiple comorbidities, to assess symptomatic improvement prior to consideration of definitive TAVI intervention...
2016: Open Heart
https://www.readbyqxmd.com/read/27942047/are-drug-eluting-stents-any-better-than-bare-metal-new-evidence-in-non-st-elevation-acute-coronary-syndrome
#19
EDITORIAL
Rahul Bahl
No abstract text is available yet for this article.
2016: Open Heart
https://www.readbyqxmd.com/read/27933194/contribution-of-the-long-term-care-insurance-certificate-for-predicting-1-year-all-cause-readmission-compared-with-validated-risk-scores-in-elderly-patients-with-heart-failure
#20
Kayo Takahashi, Makoto Saito, Shinji Inaba, Toru Morofuji, Hiroe Aisu, Takumi Sumimoto, Akiyoshi Ogimoto, Shuntaro Ikeda, Jitsuo Higaki
OBJECTIVES: Readmission is a common and serious problem associated with heart failure (HF). Unfortunately, conventional risk models have limited predictive value for predicting readmission. The recipients of long-term care insurance (LTCI) are frail and have mental and physical impairments. We hypothesised that adjustment of the conventional risk score with an LTCI certificate enables a more accurate appreciation of readmission for HF. METHODS: We investigated 452 patients with HF who were followed up for 1 year to determine all-cause readmission...
2016: Open Heart
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