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Open Heart

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https://www.readbyqxmd.com/read/28008358/impact-of-microvascular-obstruction-on-semiautomated-techniques-for-quantifying-acute-and-chronic-myocardial-infarction-by-cardiovascular-magnetic-resonance
#1
Heerajnarain Bulluck, Stefania Rosmini, Amna Abdel-Gadir, Anish N Bhuva, Thomas A Treibel, Marianna Fontana, Shane Weinmann, Alex Sirker, Anna S Herrey, Charlotte Manisty, James C Moon, Derek J Hausenloy
AIMS: The four most promising semiautomated techniques (5-SD, 6-SD, Otsu and the full width half maximum (FWHM)) were compared in paired acute and follow-up cardiovascular magnetic resonance (CMR), taking into account the impact of microvascular obstruction (MVO) and using automated extracellular volume fraction (ECV) maps for reference. Furthermore, their performances on the acute scan were compared against manual myocardial infarct (MI) size to predict adverse left ventricular (LV) remodelling (≥20% increase in end-diastolic volume)...
2016: Open Heart
https://www.readbyqxmd.com/read/28008357/bicuspid-aortic-valve-disease-systematic-review-and-meta-analysis-of-surgical-aortic-valve-repair
#2
Maximilian Salcher, Huseyin Naci, Sarah Pender, Titus Kuehne, Marcus Kelm
Aortic valve repair is still emerging, and its role in the treatment of bicuspid aortic valve disease (BAVD) is not yet fully understood. Our objective is to synthesise available evidence on outcomes after surgical aortic valve repair in patients with BAVD. We conducted a systematic review of clinical studies using prespecified methods for searching, identifying and selecting eligible studies in 4 databases, and synthesising results (PROSPERO 2014:CRD42014014415). 2 researchers independently reviewed full-text articles and extracted data...
2016: Open Heart
https://www.readbyqxmd.com/read/28008356/frailty-is-associated-with-delirium-and-mortality-after-transcatheter-aortic-valve-implantation
#3
Patricia Assmann, Peter Kievit, Kees van der Wulp, Michel Verkroost, Luc Noyez, Hans Bor, Yvonne Schoon
OBJECTIVE: We hypothesised that frailty assessment is of additional value to predict delirium and mortality after transcatheter aortic valve implantation (TAVI). METHODS: Observational study in 89 consecutive patients who underwent TAVI. Inclusion from November 2012 to February 2014, follow-up until April 2014. Measurement of the association of variables from frailty assessment and cardiological assessment with delirium and mortality after TAVI, respectively. RESULTS: Incidence of delirium after TAVI: 25/89 (28%)...
2016: Open Heart
https://www.readbyqxmd.com/read/28008355/distinguishing-between-those-dying-suddenly-or-not-suddenly-from-coronary-heart-disease-long-term-prospective-results-from-the-northwick-park-heart-study
#4
Tom Meade, Tim Clayton, Douglas Chamberlain
AIM: To establish whether ECG findings are associated with subsequent risk of sudden death from coronary heart disease (CHD). METHODS AND RESULTS: Potential risk factors for CHD were measured at entry to the first Northwick Park Heart Study of 2167 men. ECG findings were coded as high or low risk for CHD according to definitions in the Minnesota code. Sudden or non-sudden deaths were defined as occurring in less than or more than 24 hours, respectively. The only factor independently associated with sudden death among the 262 men dying of CHD was high-risk ECG...
2016: Open Heart
https://www.readbyqxmd.com/read/28008354/percutaneous-balloon-aortic-valvuloplasty-in-the-era-of-transcatheter-aortic-valve-implantation-a-narrative-review
#5
Thomas R Keeble, Arif Khokhar, Mohammed Majid Akhtar, Anthony Mathur, Roshan Weerackody, Simon Kennon
The role of percutaneous balloon aortic valvuloplasty (BAV) in the management of severe symptomatic aortic stenosis has come under the spotlight following the development of the transcatheter aortic valve implantation (TAVI) technique. Previous indications for BAV were limited to symptom palliation and as a bridge to definitive therapy for patients undergoing conventional surgical aortic valve replacement (AVR). In the TAVI era, BAV may also be undertaken to assess the 'therapeutic response' of a reduction in aortic gradient in borderline patients often with multiple comorbidities, to assess symptomatic improvement prior to consideration of definitive TAVI intervention...
2016: Open Heart
https://www.readbyqxmd.com/read/27942047/are-drug-eluting-stents-any-better-than-bare-metal-new-evidence-in-non-st-elevation-acute-coronary-syndrome
#6
EDITORIAL
Rahul Bahl
No abstract text is available yet for this article.
2016: Open Heart
https://www.readbyqxmd.com/read/27933194/contribution-of-the-long-term-care-insurance-certificate-for-predicting-1-year-all-cause-readmission-compared-with-validated-risk-scores-in-elderly-patients-with-heart-failure
#7
Kayo Takahashi, Makoto Saito, Shinji Inaba, Toru Morofuji, Hiroe Aisu, Takumi Sumimoto, Akiyoshi Ogimoto, Shuntaro Ikeda, Jitsuo Higaki
OBJECTIVES: Readmission is a common and serious problem associated with heart failure (HF). Unfortunately, conventional risk models have limited predictive value for predicting readmission. The recipients of long-term care insurance (LTCI) are frail and have mental and physical impairments. We hypothesised that adjustment of the conventional risk score with an LTCI certificate enables a more accurate appreciation of readmission for HF. METHODS: We investigated 452 patients with HF who were followed up for 1 year to determine all-cause readmission...
2016: Open Heart
https://www.readbyqxmd.com/read/27933193/outcomes-of-ischaemic-mitral-regurgitation-in-anterior-versus-inferior-st-elevation-myocardial-infarction
#8
Amgad Mentias, Mohammad Q Raza, Amr F Barakat, Elizabeth Hill, Dalia Youssef, Amar Krishnaswamy, Milind Y Desai, Brian Griffin, Stephen Ellis, Venu Menon, E Murat Tuzcu, Samir R Kapadia
BACKGROUND: Ischaemic mitral regurgitation (IMR) is a detrimental complication of ST elevation myocardial infarction (STEMI). OBJECTIVE: We sought to determine patient characteristics and outcomes of patients with IMR with focus on anterior or inferior location of STEMI. METHODS: All patients presenting with STEMI complicated by IMR to our centre who underwent primary percutaneous coronary intervention within the first 12 hours of presentation from 1995 to 2014 were included...
2016: Open Heart
https://www.readbyqxmd.com/read/27933192/randomised-comparison-of-drug-eluting-versus-bare-metal-stenting-in-patients-with-non-st-elevation-myocardial-infarction
#9
Wouter S Remkes, Erik A Badings, Renicus S Hermanides, Saman Rasoul, Jan-Henk E Dambrink, Petra C Koopmans, Salem Hk The, Jan Paul Ottervanger, A T Marcel Gosselink, Jan Ca Hoorntje, Harry Suryapranata, Arnoud Wj van 't Hof
OBJECTIVE: The superiority of drug-eluting stents (DES) over bare-metal stents (BMS) in patients with ST elevation myocardial infarction (STEMI) is well studied; however, randomised data in patients with non-ST elevation myocardial infarction (NSTEMI) are lacking. The objective of this study was to investigate whether stenting with everolimus-eluting stents (EES) safely reduces restenosis in patients with NSTEMI as compared to BMS. METHODS: ELISA-3 patients were asked to participate in the angiographic substudy and were randomised to DE (Xience V) or BM (Vision) stenting (ELISA-3 group)...
2016: Open Heart
https://www.readbyqxmd.com/read/27933191/genetics-of-inherited-cardiocutaneous-syndromes-a-review
#10
REVIEW
Tara Bardawil, Samar Khalil, Christina Bergqvist, Ossama Abbas, Abdul Ghani Kibbi, Fadi Bitar, Georges Nemer, Mazen Kurban
The life of a human being originates as a single cell which, under the influence of certain factors, divides sequentially into multiple cells that subsequently become committed to develop and differentiate into the different structures and organs. Alterations occurring early on in the development process may lead to fetal demise in utero. Conversely, abnormalities at later stages may result in structural and/or functional abnormalities of varying severities. The cardiovascular system and skin share certain developmental and structural factors; therefore, it is not surprising to find several inherited syndromes with both cardiac and skin manifestations...
2016: Open Heart
https://www.readbyqxmd.com/read/27843570/bioresorbable-vascular-scaffold-promises-and-the-fallen-child-as-king
#11
EDITORIAL
Stephane Cook, Pascal Meier
No abstract text is available yet for this article.
2016: Open Heart
https://www.readbyqxmd.com/read/27843569/conceptual-model-for-early-health-technology-assessment-of-current-and-novel-heart-valve-interventions
#12
Simone A Huygens, Maureen P M H Rutten-van Mölken, Jos A Bekkers, Ad J J C Bogers, Carlijn V C Bouten, Steven A J Chamuleau, Peter P T de Jaegere, Arie Pieter Kappetein, Jolanda Kluin, Nicolas M D A van Mieghem, Michel I M Versteegh, Maarten Witsenburg, Johanna J M Takkenberg
OBJECTIVE: The future promises many technological advances in the field of heart valve interventions, like tissue-engineered heart valves (TEHV). Prior to introduction in clinical practice, it is essential to perform early health technology assessment. We aim to develop a conceptual model (CM) that can be used to investigate the performance and costs requirements for TEHV to become cost-effective. METHODS: After scoping the decision problem, a workgroup developed the draft CM based on clinical guidelines...
2016: Open Heart
https://www.readbyqxmd.com/read/27843568/complementary-role-of-cardiac-ct-in-the-assessment-of-aortic-valve-replacement-dysfunction
#13
REVIEW
Alastair J Moss, Marc R Dweck, John G Dreisbach, Michelle C Williams, Sze Mun Mak, Timothy Cartlidge, Edward D Nicol, Gareth J Morgan-Hughes
Aortic valve replacement is the second most common cardiothoracic procedure in the UK. With an ageing population, there are an increasing number of patients with prosthetic valves that require follow-up. Imaging of prosthetic valves is challenging with conventional echocardiographic techniques making early detection of valve dysfunction or complications difficult. CT has recently emerged as a complementary approach offering excellent spatial resolution and the ability to identify a range of aortic valve replacement complications including structural valve dysfunction, thrombus development, pannus formation and prosthetic valve infective endocarditis...
2016: Open Heart
https://www.readbyqxmd.com/read/27843567/long-term-survival-after-coronary-bypass-surgery-and-percutaneous-coronary-intervention
#14
Per Mølstad, Rasmus Moer, Olaf Rødevand
OBJECTIVES: To assess whether there exists a long-term difference in survival after treatment with coronary bypass surgery or percutaneous coronary intervention in patients with coronary disease as judged by all-cause mortality. METHODS: Retrospective study from the Feiring Heart Clinic database of survival in 22 880 patients-15 078 treated with percutaneous coronary intervention and 7802 with bypass surgery followed up to 16 years. RESULTS: Cox regression and propensity score analysis showed no difference in survival for one-vessel and two-vessel disease during the whole study period...
2016: Open Heart
https://www.readbyqxmd.com/read/27843566/exercise-restrictions-trigger-psychological-difficulty-in-active-and-athletic-adults-with-hypertrophic-cardiomyopathy
#15
Rebecca C Luiten, Kelly Ormond, Lisa Post, Irfan M Asif, Matthew T Wheeler, Colleen Caleshu
OBJECTIVE: We examined the extent and nature of the psychological difficulty experienced by athletic adults with hypertrophic cardiomyopathy (HCM), correlates of that difficulty and coping mechanisms. METHODS: A survey assessed athletic history and psychological impact of exercise restrictions. LASSO penalised linear regression identified factors associated with psychological difficulty. Semistructured interviews provided deeper insight into the nature and origins of psychological difficulty...
2016: Open Heart
https://www.readbyqxmd.com/read/27843565/systematic-reviews-causes-of-non-adherence-to-p2y12-inhibitors-in-acute-coronary-syndromes-and-response-to-intervention
#16
Nina Johnston, John Weinman, Lucy Ashworth, Peter Smethurst, Jad El Khoury, Clare Moloney
To understand the factors associated with non-adherence to oral antiplatelet (OAP) therapy in acute coronary syndromes (ACS), and where interventions have modified these factors. Linked systematic reviews were undertaken in accordance with the Preferred Reporting Items for Systematic reviews and Meta-analysis guidelines, using CINAHL Plus, MEDLINE, PsycINFO and PubMed databases. The searches were limited to studies available in English and published from 2000 onwards; last run in June 2015. Review 1: factors...
2016: Open Heart
https://www.readbyqxmd.com/read/27843564/bleeding-events-and-maintenance-dose-of-prasugrel-bless-pilot-study
#17
Nazario Carrabba, Guido Parodi, Rossella Marcucci, Renato Valenti, Anna Maria Gori, Angela Migliorini, Vincenzo Comito, Benedetta Bellandi, Rosanna Abbate, Gian Franco Gensini, David Antoniucci
OBJECTIVE: To evaluate changes in residual platelet reactivity (RPR) over time, and bleeding and ischaemic events rate using 5 vs 10 mg maintenance dose (MD) regimens of prasugrel 1 month after acute coronary syndrome (ACS). BACKGROUND: The optimal level of RPR with prasugrel may change over time after an ACS. METHODS: After 60 mg loading dose of prasugrel (T0) followed by 10 mg/day for 1 month, patients were randomised to receive prasugrel 10 mg/day (n=95, group A) or 5 mg/day MD (n=98, group B) up to 1 year...
2016: Open Heart
https://www.readbyqxmd.com/read/27843563/the-importance-of-a-balanced-%C3%AF-6-to-%C3%AF-3-ratio-in-the-prevention-and-management-of-obesity
#18
EDITORIAL
Artemis P Simopoulos, James J DiNicolantonio
No abstract text is available yet for this article.
2016: Open Heart
https://www.readbyqxmd.com/read/27843562/risk-factors-of-diabetic-cardiac-autonomic-neuropathy-in-patients-with-type-1-diabetes-mellitus-a-meta-analysis
#19
Mohamed D Dafaalla, Mohammed N Nimir, Mosab I Mohammed, Omer A Ali, Abbashar Hussein
OBJECTIVES: We aimed to stratify the possible risk factors for diabetic cardiac autonomic neuropathy (CAN). METHODS: We did a meta-analysis of risk factors of CAN. We did a web-based search for literature in MEDLINE/PubMed, Scopus database and CENTRAL database up to August 2015. We included clinical trials or cohort studies that provide data about relationship between CAN and variables of interest. Our risk factors of interest were age, sex, duration of diabetes, body mass index (BMI), systolic blood pressure (sBP) and diastolic blood pressure (dBP), glycated haemoglobin (HbA1c), high-density lipoprotein and low-density lipoprotein (HDL and LDL), triglycerides, retinopathy and nephropathy...
2016: Open Heart
https://www.readbyqxmd.com/read/27843561/predictors-of-poor-outcome-among-children-with-heterotaxy-syndrome-a-retrospective-review
#20
Eiméar McGovern, Eoin Kelleher, James E Potts, John O'Brien, Kevin Walsh, Lars Nolke, Colin J McMahon
OBJECTIVE: To determine predictors of poor outcome in patients with heterotaxy syndrome. METHODS: A retrospective review of children with heterotaxy syndrome, in a single tertiary paediatric cardiology centre, was conducted between 1 January 1997 and 1 January 2014 to determine predictors of poor outcome. Poor outcome was defined as death, cardiac transplantation or New York Heart Association (NYHA) functional class III or IV. RESULTS: There were 35 patients diagnosed with heterotaxy syndrome, 17 of whom were diagnosed antenatally...
2016: Open Heart
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