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Sexual Medicine

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https://www.readbyqxmd.com/read/28041924/what-sexual-behaviors-relate-to-decreased-sexual-desire-in-women-a-review-and-proposal-for-end-points-in-treatment-trials-for-hypoactive-sexual-desire-disorder
#1
REVIEW
Robert Pyke, Anita Clayton
INTRODUCTION: Counts of satisfying sexual events (SSEs) per month have been criticized as an end point in treatment trials of women with hypoactive sexual desire disorder (HSDD) but grounding improvement in sexual desire by assessing changes in sexual behavior remains of some importance. METHODS: We conducted a literature review to find validated measurements that are specific sexual behavioral correlates of low sexual desire. We compared expert-proposed criteria for dysfunctional desire, expert-developed sets of scale items, and self-rated scales developed before issuance of, or in accordance with, the Food and Drug Administration's guidance on developing patient-reported outcomes...
December 29, 2016: Sexual Medicine
https://www.readbyqxmd.com/read/28190453/an-empirical-vs-risk-based-approach-algorithm-to-intracavernosal-injection-therapy-a-prospective-study
#2
Helen Levey Bernie, Robert Segal, Brian Le, Arthur Burnett, Trinity J Bivalacqua
INTRODUCTION: Intracavernosal injection (ICI) therapy is widely used for the treatment of erectile dysfunction (ED). Its use in practice is largely empirical and has not been validated with evidence-based approaches. AIM: To compare two strategies for ICI, specifically a risk-based approach and an empiric-based approach, and assess the efficacy, patient satisfaction, and complication rates of the two treatment approaches. METHODS: After obtaining approval from the institutional review board, a prospective database of patients enrolled in the ICI program at the Johns Hopkins Hospital (Baltimore, MD, USA) from May 2012 through May 2014 was amassed...
March 2017: Sexual Medicine
https://www.readbyqxmd.com/read/28087237/what-is-the-real-impact-of-urinary-incontinence-on-female-sexual-dysfunction-a-case-control-study
#3
Mariana Rhein Felippe, Joao Paulo Zambon, Marcia Eli Girotti, Juliana Schulze Burti, Claudia Rosenblatt Hacad, Lina Cadamuro, Fernando Almeida
INTRODUCTION: Urinary incontinence (UI) has been associated with negative effects on women's sexuality. Women's sexuality and sexual function are a complex issue, and the role of UI is not completely clear. AIM: To assess the impact of UI on female sexual function by comparing this population with a control group of continent women. METHODS: We performed a case-control study from August 2012 to September 2013. We evaluated continent and incontinent women (age range = 30-70 years) for their sexuality...
March 2017: Sexual Medicine
https://www.readbyqxmd.com/read/28041925/complementary-and-alternative-medicine-for-management-of-premature-ejaculation-a-systematic-review
#4
REVIEW
Katy Cooper, Marrissa Martyn-St James, Eva Kaltenthaler, Kath Dickinson, Anna Cantrell, Shijie Ren, Kevan Wylie, Leila Frodsham, Catherine Hood
INTRODUCTION: Premature ejaculation (PE) is defined as ejaculation within 1 minute (lifelong PE) or 3 minutes (acquired PE), inability to delay ejaculation, and negative personal consequences. Management includes behavioral and pharmacologic approaches. AIM: To systematically review effectiveness, safety, and robustness of evidence for complementary and alternative medicine in managing PE. METHODS: Nine databases including Medline were searched through September 2015...
March 2017: Sexual Medicine
https://www.readbyqxmd.com/read/28041923/prevalence-and-associated-factors-of-premature-ejaculation-in-the-anhui-male-population-in-china-evidence-based-unified-definition-of-lifelong-and-acquired-premature-ejaculation
#5
Jingjing Gao, Dangwei Peng, Xiansheng Zhang, Zongyao Hao, Jun Zhou, Song Fan, Yao Zhang, Jun Mao, Xianming Dou, Chaozhao Liang
INTRODUCTION: In 2014, new evidence-based definitions of lifelong premature ejaculation (LPE) and acquired premature ejaculation (APE) were proposed by the International Society for Sexual Medicine. Based on the new PE definitions, the prevalence of and factors associated with LPE and APE have not been investigated in China. AIM: To evaluate the prevalence of and factors associated with LPE and APE in men with the complaint of PE in China. METHODS: From December 2011 to December 2015, a cross-sectional field survey was conducted in five cities in the Anhui province of China...
March 2017: Sexual Medicine
https://www.readbyqxmd.com/read/28024997/androgen-receptor-ar-gene-cag-n-and-ggn-n-length-polymorphisms-and-symptoms-in-young-males-with-long-lasting-adverse-effects-after-finasteride-use-against-androgenic-alopecia
#6
Sabina Cauci, Giovanni Chiriacò, Erika Cecchin, Giuseppe Toffoli, Serena Xodo, Giuseppe Stinco, Carlo Trombetta
INTRODUCTION: Long-term adverse symptoms of men who used oral finasteride against androgenic alopecia have been recently described as post-finasteride syndrome (PFS). AIM: To determine whether (CAG)n-rs4045402 and (GGN)n-rs3138869 polymorphisms in the androgen receptor (AR) gene are implicated in PFS. METHODS: AR polymorphisms were studied according to PFS symptoms in 66 white participants (31.8% Italian, 28.8% American, and 39.4% other). MAIN OUTCOME MEASURES: Symptoms were investigated by an ad hoc 100-item questionnaire and the Arizona Sexual Experience Scale and Aging Male Symptom Scale (AMS)...
March 2017: Sexual Medicine
https://www.readbyqxmd.com/read/28024996/meta-analysis-of-prevalence-of-erectile-dysfunction-in-mainland-china-evidence-based-on-epidemiological-surveys
#7
Wenying Wang, Jingyuan Fan, Guifeng Huang, Xi Zhu, Ye Tian, Hua Tan, Li Su
INTRODUCTION: The epidemiologic characteristics of erectile dysfunction (ED) in mainland China remain incompletely understood. AIM: To evaluate the overall prevalence and determine the severity of ED in mainland China. METHODS: An extensive database search was performed of PubMed, Embase, the Chinese National Knowledge Infrastructure (CNKI) database, the WanFang database, the Chinese Biological Medical Literature (CBM) database, and the Chongqing VIP using the following terms: erectile dysfunction, prevalence, epidemiology, epidemiological, and China...
March 2017: Sexual Medicine
https://www.readbyqxmd.com/read/27988217/attitudes-and-performance-of-cardiologists-toward-sexual-issues-in-cardiovascular-patients
#8
Razieh Salehian, Fatemeh Khodaeifar, Morteza Naserbakht, Azadeh Meybodi
INTRODUCTION: The aim of the present study was to evaluate the attitudes and performance of cardiologists regarding sexual issues in patients with cardiovascular diseases. METHODS: A nationwide survey was conducted in a sample of cardiologists, representative of Iranian cardiologists, in 2015. MAIN OUTCOME MEASURES: Appropriate questionnaires were developed and used to ask participants about their attitudes, performance, and barriers regarding discussing sexual issues with patients with cardiovascular disease...
March 2017: Sexual Medicine
https://www.readbyqxmd.com/read/27528556/initiators-and-barriers-to-discussion-and-treatment-of-premature-ejaculation-among-men-and-their-partners-in-asia-pacific-results-from-a-web-based-survey
#9
George Lee, Chris G McMahon, Marita McCabe, Hui Jiang, Sung Won Lee, Peter Lim, Bang-Ping Jiann
INTRODUCTION: Premature ejaculation (PE) is one of the most prevalent yet under-reported sexual disorders. Differing sociocultural norms across the Asia-Pacific region provide unique challenges in PE management. METHODS: This web-based study collected data from 5,038 men and women across 11 countries in the Asia-Pacific region. Respondents were recruited from an existing database. MAIN OUTCOME MEASURES: The initiators and barriers for PE discussions and for seeking professional management following self-treatment, as well as their choices and expectations of healthcare professionals (HCPs)...
December 2016: Sexual Medicine
https://www.readbyqxmd.com/read/27484917/what-do-patients-want-a-needs-assessment-of-vulvodynia-patients-attending-a-vulvar-diseases-clinic
#10
Katherine LePage, Amanda Selk
INTRODUCTION: Vulvodynia is a chronic pain disorder that negatively impacts the quality of life of affected women. AIM: The goal of this study was to identify unmet needs among localized provoked vulvodynia patients. METHODS: A qualitative needs assessment was performed in a subspecialized vulvar clinic in a single academic institution in Canada. Semistructured interviews were conducted, recorded, and analyzed using the constant comparative method of grounded theory to identify common themes...
December 2016: Sexual Medicine
https://www.readbyqxmd.com/read/27484916/local-treatment-of-penile-prosthesis-infection-as-alternative-to-immediate-salvage-surgery
#11
Saturnino Luján, Ramón Rogel, Enrique Broseta, Francisco Boronat
INTRODUCTION: Penile prosthesis (PP) is the established treatment for patients with erectile dysfunction (ED) who do not respond to phosphodiesterase inhibitors and intracavernosal injections. In general, these devices have been largely successful but there are not free of serious complication such as PP infection (PPI). PPI requires immediate surgical removal or salvage rescue of the PP. AIM: In this report, we present two clinical cases with inflatable PP (IPP) treated locally with antibiotic and high pressure irrigation and then avoid the PP removal or salvage rescue...
December 2016: Sexual Medicine
https://www.readbyqxmd.com/read/27461974/all-trans-retinoic-acid-increases-aquaporin-3-expression-in-human-vaginal-epithelial-cells
#12
Hyun-Suk Lee, Sun-Ouck Kim, Kyuyoun Ahn, Kwangsung Park
INTRODUCTION: Water channel aquaporin 3 (AQP3) is an aquaglyceroporin that transports small neutral solutes and water. All-trans retinoic acid (ATRA), a member of the retinoid drug class, acts as a regulator in several biological processes. AIM: To investigate the effect of ATRA on the expression of AQP3 in human vaginal epithelial cells. METHODS: Human vaginal mucosal epithelial cells (CRL2616) were treated with ATRA 0, 0.01, 0.1, and 1 μmol/L for 24 hours to examine the dose-dependent effects of ATRA and with ATRA 1 μmol/L for 0, 3, 6, 12, and 24 hours...
December 2016: Sexual Medicine
https://www.readbyqxmd.com/read/27444215/twelve-month-efficacy-and-safety-of-low-intensity-shockwave-therapy-for-erectile-dysfunction-in-patients-who-do-not-respond-to-phosphodiesterase-type-5-inhibitors
#13
Amado Bechara, Adolfo Casabé, Walter De Bonis, Pablo Gomez Ciciclia
INTRODUCTION: Low-intensity shockwave therapy (LISWT) has recently emerged as a promising method in the treatment of erectile dysfunction (ED). AIM: To assess the long-term results of the effectiveness and safety of LISWT in patients with ED who are non-responders to phosphodiesterase type 5 inhibitor (PDE5i) treatment. METHODS: This open-label, longitudinal, and observational study investigated an uncontrolled population of 50 consecutive patients whose ED was unresponsive to PDE5i treatment...
December 2016: Sexual Medicine
https://www.readbyqxmd.com/read/27375006/relation-between-erectile-dysfunction-and-silent-myocardial-ischemia-in-diabetic-patients-a-multidetector-computed-tomographic-coronary-angiographic-study
#14
Amr Abdelhamed, Shin-Ichi Hisasue, Essam A Nada, Ali M Kassem, Mohammed Abdel-Kareem, Shigeo Horie
INTRODUCTION: Erectile dysfunction (ED) can precede coronary artery disease. In addition, silent myocardial ischemia (SMI) is more common in diabetic patients and is a strong predictor of cardiac events and death. AIM: To evaluate the presence of SMI in patients with diabetes and ED using multidetector computed tomographic coronary angiography (MDCT-CA). METHODS: This study evaluated patients with diabetes and ED without any history of cardiac symptoms or signs...
September 2016: Sexual Medicine
https://www.readbyqxmd.com/read/27373143/ospemifene-may-not-treat-vulvar-atrophy-a-report-of-two-cases
#15
Andrew T Goldstein, Michelle A King
INTRODUCTION: Ospemifene (Osphena, Shionogi Inc, Florham, NJ, USA) is an estrogen agonist and antagonist approved by the U.S. Federal Drug Administration for the treatment of "moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause." Although published, peer-reviewed, placebo-controlled studies have shown objective improvement in dyspareunia and in vaginal atrophy, there are no published data that have assessed changes in vulvar atrophy after the use of ospemifene...
September 2016: Sexual Medicine
https://www.readbyqxmd.com/read/27346231/attitudes-of-sexual-medicine-specialists-toward-premature-ejaculation-diagnosis-and-therapy
#16
Arik Shechter, Lior Lowenstein, Ege Can Serefoglu, Yacov Reisman
INTRODUCTION: Premature ejaculation (PE) is one of the commonest sexual dysfunctions in men. Because the definition of and guidelines for the management of PE have been revised in recent years, our understanding of PE has changed. AIM: To investigate the clinical practice patterns of sexual medicine specialists regarding the diagnosis and treatment of PE. METHODS: Attendees of the 17th Annual Congress of the European Society of Sexual Medicine, held in February 2015 in Copenhagen, Denmark, were asked to participate in a survey during the congress...
September 2016: Sexual Medicine
https://www.readbyqxmd.com/read/27320409/orgasm-serotonin-reuptake-inhibition-and-plasma-oxytocin-in-obsessive-compulsive-disorder-gleaning-from-a-distant-randomized-clinical-trial
#17
Mats B Humble, Susanne Bejerot
INTRODUCTION: Serotonin reuptake inhibitors (SRIs) are widely used for the treatment of psychiatric disorders, including obsessive-compulsive disorder (OCD). SRIs commonly cause delayed orgasm, the mechanism of which is poorly understood. Oxytocin is involved in sexual function and is interconnected with serotonin within the brain. SRIs are reported to affect the oxytocin system, but possible relations between SRI-induced changes of sexual function and oxytocin are unexplored in humans...
September 2016: Sexual Medicine
https://www.readbyqxmd.com/read/27267138/undergraduate-training-in-human-sexuality-evaluation-of-the-impact-on-medical-doctors-practice-ten-years-after-graduation
#18
Mary Clegg, Joanne Pye, Kevan R Wylie
INTRODUCTION: It has been suggested that an indicator of a doctor's ability to assess patients' sexual function relates to the level of earlier training. The amount and quality of training the doctor receives at the undergraduate level and beyond could contribute to the doctor's confidence and competence. AIMS: To evaluate whether doctors found that the teaching in human sexuality received at medical school was sufficient for their future practice and whether their chosen medical specialty and exposure to issues related to sexual health affected this opinion...
September 2016: Sexual Medicine
https://www.readbyqxmd.com/read/27234319/penile-traumatic-neuroma-a-late-complication-of-penile-dorsal-neurotomy-to-treat-premature-ejaculation
#19
Hyun Jun Park, Tae Nam Kim, Seung Ryong Baek, Kyung Min Lee, Kyung-Un Choi, Nam Cheol Park
INTRODUCTION: Traumatic neuroma is a reactive process caused by the regeneration of an injured nerve that usually forms a nodular proliferation of small nerve bundles. Penile traumatic neuroma is rare; only a few cases related to circumcision have been reported. AIM: To report on a case of traumatic neuroma in the penis after selective dorsal neurotomy (SDN) to treat premature ejaculation. METHODS: The penile traumatic neuroma was successfully removed by excision and confirmed by histopathology...
September 2016: Sexual Medicine
https://www.readbyqxmd.com/read/27165191/the-sexual-impact-of-infertility-among-women-seeking-fertility-care
#20
William D Winkelman, Patricia P Katz, James F Smith, Tami S Rowen
INTRODUCTION: Infertility affects approximately 6.7 million women in the United States. Couples with infertility have significantly more anxiety, depression, and stress. This is compounded by the fact that almost 40% of couples undergoing assisted reproduction technology still cannot conceive, which can have an ongoing effect on quality of life, marital adjustment, and sexual impact. AIM: To assess the sexual impact of infertility in women undergoing fertility treatment...
September 2016: Sexual Medicine
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