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Journal of Intensive Care

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https://www.readbyqxmd.com/read/27891229/nicotine-replacement-therapy-for-agitation-and-delirium-management-in-the-intensive-care-unit-a-systematic-review-of-the-literature
#1
Melanie Kowalski, Andrew A Udy, Hayden J McRobbie, Michael J Dooley
BACKGROUND: Active smokers are prevalent within the intensive care setting and place a significant burden on healthcare systems. Nicotine withdrawal due to forced abstinence on admission may contribute to increased agitation and delirium in this patient group. The aim of this systematic review was to determine whether management of nicotine withdrawal, with nicotine replacement therapy (NRT), reduces agitation and delirium in critically ill patients admitted to the intensive care unit (ICU)...
2016: Journal of Intensive Care
https://www.readbyqxmd.com/read/27833752/accuracy-of-critical-care-pain-observation-tool-and-behavioral-pain-scale-to-assess-pain-in-critically-ill-conscious-and-unconscious-patients-prospective-observational-study
#2
Paolo Severgnini, Paolo Pelosi, Elena Contino, Elisa Serafinelli, Raffaele Novario, Maurizio Chiaranda
BACKGROUND: Critically ill patients admitted to intensive care unit (ICU) may suffer from different painful stimuli, but the assessment of pain is difficult because most of them are almost sedated and unable to self-report. Thus, it is important to optimize evaluation of pain in these patients. The main aim of this study was to compare two commonly used scales for pain evaluation: Critical Care Pain Observation Tool (CPOT) and Behavioral Pain Scale (BPS), in both conscious and unconscious patients...
2016: Journal of Intensive Care
https://www.readbyqxmd.com/read/27826449/perspective-on-optimizing-clinical-trials-in-critical-care-how-to-puzzle-out-recurrent-failures
#3
REVIEW
Bruno François, Marc Clavel, Philippe Vignon, Pierre-François Laterre
BACKGROUND: Critical care is a complex field of medicine, especially because of its diversity and unpredictability. Mortality rates of the diseases are usually high and patients are critically ill, admitted in emergency, and often have several overlapping diseases. This makes research in critical care also complex because of patients' conditions and because of the numerous ethical and regulatory requirements and increasing global competition. Many clinical trials in critical care have thus failed and almost no drug has yet been developed to treat intensive care unit (ICU) patients...
2016: Journal of Intensive Care
https://www.readbyqxmd.com/read/27800164/current-rehabilitation-practices-in-intensive-care-units-a-preliminary-survey-by-the-japanese-society-of-education-for-physicians-and-trainees-in-intensive-care-jseptic-clinical-trial-group
#4
Shunsuke Taito, Masamitsu Sanui, Hideto Yasuda, Nobuaki Shime, Alan Kawarai Lefor
We conducted an internet survey targeting healthcare providers in intensive care units (ICUs) in Japan and received 318 responses. Eighteen percent of respondents replied that full-time physical therapists (PTs) exist in their ICUs. Practicing sitting upright or sitting in a chair is frequently performed, while standing and walking are occasionally performed for patients undergoing mechanical ventilation. However, only 16 % of respondents use staged rehabilitation protocols. This preliminary survey suggests that full-time involvement of PTs in the ICU and introduction of rehabilitation protocols may not be common in Japanese ICUs...
2016: Journal of Intensive Care
https://www.readbyqxmd.com/read/27800163/validity-of-the-richmond-agitation-sedation-scale-rass-in-critically-ill-children
#5
Abigail Glicksman Kerson, Rebecca DeMaria, Elizabeth Mauer, Christine Joyce, Linda M Gerber, Bruce M Greenwald, Gabrielle Silver, Chani Traube
BACKGROUND: The Richmond Agitation-Sedation Scale (RASS) is a single tool that is intuitive, is easy to use, and includes both agitation and sedation. The RASS has never been formally validated for pediatric populations. The objective of this study was to assess inter-rater agreement and criterion validity of the RASS in critically ill children. METHODS: To evaluate validity, the RASS score was compared to both a visual analog scale (VAS) scored by the patient's nurse, and the University of Michigan Sedation Scale (UMSS), performed by a researcher...
2016: Journal of Intensive Care
https://www.readbyqxmd.com/read/27777780/initial-central-venous-pressure-could-be-a-prognostic-marker-for-hemodynamic-improvement-of-polymyxin-b-direct-hemoperfusion-a-retrospective-cohort-study
#6
Hiroyuki Yamada, Tatsuo Tsukamoto, Hiromichi Narumiya, Kazumasa Oda, Satoshi Higaki, Ryoji Iizuka, Motoko Yanagita, Masako Deguchi
BACKGROUND: Direct hemoperfusion with polymyxin B-immobilized fiber column (PMX-DHP) could improve the hemodynamic status of septic shock patients. As PMX-DHP is an invasive and costly procedure, it is desirable to estimate the therapeutic effect before performing the therapy. However, it is still unclear when this therapy should be started and what type of sepsis it should be employed for. In this study, we retrospectively examined the clinical effect of patients treated with PMX-DHP by using central venous pressure (CVP)...
2016: Journal of Intensive Care
https://www.readbyqxmd.com/read/27729984/augmented-renal-clearance-in-japanese-intensive-care-unit-patients-a-prospective-study
#7
Yasumasa Kawano, Shinichi Morimoto, Yoshito Izutani, Kentaro Muranishi, Hironari Kaneyama, Kota Hoshino, Takeshi Nishida, Hiroyasu Ishikura
BACKGROUND: Augmented renal clearance (ARC) of circulating solutes and drugs has been recently often reported in intensive care unit (ICU) patients. However, only few studies on ARC have been reported in Japan. The aims of this pilot study were to determine the prevalence and risk factors for ARC in Japanese ICU patients with normal serum creatinine levels and to evaluate the association between ARC and estimated glomerular filtration rate (eGFR) calculated using the Japanese equation...
2016: Journal of Intensive Care
https://www.readbyqxmd.com/read/27721980/fluid-responsiveness-prediction-using-vigileo-flotrac-measured-cardiac-output-changes-during-passive-leg-raise-test
#8
Anton Krige, Martin Bland, Thomas Fanshawe
BACKGROUND: Passive leg raising (PLR) is a so called self-volume challenge used to test for fluid responsiveness. Changes in cardiac output (CO) or stroke volume (SV) measured during PLR are used to predict the need for subsequent fluid loading. This requires a device that can measure CO changes rapidly. The Vigileo™ monitor, using third-generation software, allows continuous CO monitoring. The aim of this study was to compare changes in CO (measured with the Vigileo device) during a PLR manoeuvre to calculate the accuracy for predicting fluid responsiveness...
2016: Journal of Intensive Care
https://www.readbyqxmd.com/read/27672440/retraction-note-brain-injury-following-cardiac-arrest-pathophysiology-for-neurocritical-care
#9
Hiroyuki Uchino, Yukihiko Ogihara, Hidekimi Fukui, Miyuki Chijiiwa, Shusuke Sekine, Naomi Hara, Eskil Elmér
[This retracts the article DOI: 10.1186/s40560-016-0140-9.].
2016: Journal of Intensive Care
https://www.readbyqxmd.com/read/27651904/erratum-to-comments-to-risk-factors-for-late-defecation-and-its-association-with-the-outcomes-of-critically-ill-patients-a-retrospective-observational-study
#10
Dominique Prat, Benjamin Sztrymf
[This corrects the article DOI: 10.1186/s40560-016-0170-3.].
2016: Journal of Intensive Care
https://www.readbyqxmd.com/read/27617097/glycocalyx-and-its-involvement-in-clinical-pathophysiologies
#11
REVIEW
Akira Ushiyama, Hanae Kataoka, Takehiko Iijima
Vascular hyperpermeability is a frequent intractable feature involved in a wide range of diseases in the intensive care unit. The glycocalyx (GCX) seemingly plays a key role to control vascular permeability. The GCX has attracted the attention of clinicians working on vascular permeability involving angiopathies, and several clinical approaches to examine the involvement of the GCX have been attempted. The GCX is a major constituent of the endothelial surface layer (ESL), which covers most of the surface of the endothelial cells and reduces the access of cellular and macromolecular components of the blood to the surface of the endothelium...
2016: Journal of Intensive Care
https://www.readbyqxmd.com/read/27595002/light-irradiation-for-treatment-of-acute-carbon-monoxide-poisoning-an-experimental-study
#12
Taku Tanaka, Takeshi Kashimura, Marii Ise, Brandon D Lohman, Yasuhiko Taira
BACKGROUND: Because treatment modalities for carbon monoxide (CO) poisoning, especially normobaric oxygen and hyperbaric oxygen therapies, have limited effects and hyperbaric oxygen is not available at the scene where treatment is most needed, we conducted a study to determine and compare rates of carboxyhemoglobin (COHb) dissociation achieved in human in vitro blood samples under light radiation emitted at three levels of illuminance. This was done with a view toward eventual on-site application...
2016: Journal of Intensive Care
https://www.readbyqxmd.com/read/27588206/lung-ultrasound-a-primary-survey-of-the-acutely-dyspneic-patient
#13
REVIEW
Francis Chun Yue Lee
There has been an explosion of knowledge and application of clinical lung ultrasound (LUS) in the last decade. LUS has important applications in the ambulatory, emergency, and critical care settings and its deployability for immediate bedside assessment allows many acute lung conditions to be diagnosed and early interventional decisions made in a matter of minutes. This review detailed the scientific basis of LUS, the examination techniques, and summarises the current applications in several acute lung conditions...
2016: Journal of Intensive Care
https://www.readbyqxmd.com/read/27529031/an-overview-of-point-of-care-ultrasound-for-soft-tissue-and-musculoskeletal-applications-in-the-emergency-department
#14
REVIEW
Kuo-Chih Chen, Aming Chor-Ming Lin, Chee-Fah Chong, Tzong-Luen Wang
BACKGROUND: The skin, soft tissue, and most parts of the musculoskeletal system are relatively superficial anatomical structures and ideal targets for ultrasound examination in the emergency departments. Soft tissue and musculoskeletal ultrasound applications are relatively underused compared to traditional emergency applications, such as trauma, abdominal aortic aneurysm, and chest and cardiovascular systems. MAIN TEXT: It is important to have knowledge about sonoanatomy and landmarks within the skin, soft tissue, and musculoskeletal systems...
2016: Journal of Intensive Care
https://www.readbyqxmd.com/read/27529030/clinically-integrated-multi-organ-point-of-care-ultrasound-for-undifferentiated-respiratory-difficulty-chest-pain-or-shock-a-critical-analytic-review
#15
REVIEW
Young-Rock Ha, Hong-Chuen Toh
Rapid and accurate diagnosis and treatment are paramount in the management of the critically ill. Critical care ultrasound has been widely used as an adjunct to standard clinical examination, an invaluable extension of physical examination to guide clinical decision-making at bedside. Recently, there is growing interest in the use of multi-organ point-of-care ultrasound (MOPOCUS) for the management of the critically ill, especially in the early phase of resuscitation. This article will review the role and utility of symptom-based and sign-oriented MOPOCUS in patients with undifferentiated respiratory difficulty, chest pain, or shock and how it can be performed in a timely, effective, and efficient manner...
2016: Journal of Intensive Care
https://www.readbyqxmd.com/read/27529029/overview-of-point-of-care-abdominal-ultrasound-in-emergency-and-critical-care
#16
REVIEW
Toru Kameda, Nobuyuki Taniguchi
Point-of-care abdominal ultrasound (US), which is performed by clinicians at bedside, is increasingly being used to evaluate clinical manifestations, to facilitate accurate diagnoses, and to assist procedures in emergency and critical care. Methods for the assessment of acute abdominal pain with point-of-care US must be developed according to accumulated evidence in each abdominal region. To detect hemoperitoneum, the methodology of a focused assessment with sonography for a trauma examination may also be an option in non-trauma patients...
2016: Journal of Intensive Care
https://www.readbyqxmd.com/read/27529028/role-of-upper-airway-ultrasound-in-airway-management
#17
REVIEW
Adi Osman, Kok Meng Sum
Upper airway ultrasound is a valuable, non-invasive, simple, and portable point of care ultrasound (POCUS) for evaluation of airway management even in anatomy distorted by pathology or trauma. Ultrasound enables us to identify important sonoanatomy of the upper airway such as thyroid cartilage, epiglottis, cricoid cartilage, cricothyroid membrane, tracheal cartilages, and esophagus. Understanding this applied sonoanatomy facilitates clinician to use ultrasound in assessment of airway anatomy for difficult intubation, ETT and LMA placement and depth, assessment of airway size, ultrasound-guided invasive procedures such as percutaneous needle cricothyroidotomy and tracheostomy, prediction of postextubation stridor and left double-lumen bronchial tube size, and detecting upper airway pathologies...
2016: Journal of Intensive Care
https://www.readbyqxmd.com/read/27529027/make-it-simple-enhanced-shock-management-by-focused-cardiac-ultrasound
#18
REVIEW
Ka Leung Mok
BACKGROUND: Shock is a spectrum of circulatory failure that, if not properly managed, would lead to high mortality. Special diagnostic and treatment strategies are essential to save lives. However, clinical and laboratory findings are always non-specific, resulting in clinical dilemmas. MAIN CONTENT: Focused cardiac ultrasound (FoCUS) has emerged as one of the power tools for clinicians to answer simple clinical questions and guide subsequent management in hypotensive patients...
2016: Journal of Intensive Care
https://www.readbyqxmd.com/read/27525106/one-year-resource-utilisation-costs-and-quality-of-life-in-patients-with-acute-respiratory-distress-syndrome-ards-secondary-analysis-of-a-randomised-controlled-trial
#19
Joachim Marti, Peter Hall, Patrick Hamilton, Sarah Lamb, Chris McCabe, Ranjit Lall, Julie Darbyshire, Duncan Young, Claire Hulme
BACKGROUND: The long-term economic and quality-of-life outcomes of patients admitted to intensive care unit (ICU) with acute respiratory distress syndrome are not well understood. In this study, we investigate 1-year costs, survival and quality of life following ICU admission in patients who required mechanical ventilation for acute respiratory distress syndrome. METHODS: Economic analysis of data collected alongside a UK-based multi-centre randomised, controlled trial, aimed at comparing high-frequency oscillatory ventilation with conventional mechanical ventilation...
2016: Journal of Intensive Care
https://www.readbyqxmd.com/read/27478617/early-mobilization-of-mechanically-ventilated-patients-in-the-intensive-care-unit
#20
REVIEW
Shunsuke Taito, Nobuaki Shime, Kohei Ota, Hideto Yasuda
Several recent studies have suggested that the early mobilization of mechanically ventilated patients in the intensive care unit is safe and effective. However, in these studies, few patients reached high levels of active mobilization, and the standard of care among the studies has been inconsistent. The incidence of adverse events during early mobilization is low. Its importance should be considered in the context of the ABCDE bundle. Protocols of early mobilization with strict inclusion and exclusion criteria are needed to further investigate its contributions...
2016: Journal of Intensive Care
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