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BioMedicine

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https://www.readbyqxmd.com/read/28474583/correction-notice-to-alleviative-effects-from-boswellic-acid-on-acetaminophen-induced-hepatic-injury-biomedicine-taipei-2016-jun-6-2-9-doi-10-7603-s40681-016-0009-1
#1
https://www.readbyqxmd.com/read/28474582/delayed-extensive-lumbar-sub-dural-effusion-following-discectomy-clinical-imaging-and-case-report
#2
Arun-Kumar Kaliya-Perumal, Meng-Ling Lu, Fu-Cheng Kao, Chi-Chien Niu
Incidental durotomy during lumbar spine surgery is a commonly reported complication. Those presenting with cerebrospinal fluid (CSF) leak are usually recognized and repaired intraoperatively. In some circumstances, it may either be unrecognised or occur as a delayed complication. Such delayed occurrences cannot be predicted and its management remain a challenge to the surgeon, especially when it presents as a subdural effusion. We report a 55-year-old man who underwent mini open lumbar discectomy through left side for a prolapsed L4-L5 disc...
March 2017: BioMedicine
https://www.readbyqxmd.com/read/28474581/presentations-and-management-of-different-causes-of-chylothorax-in-children-one-medical-center-s-experience
#3
Chien-Heng Lin, Wei-Ching Lin, Jeng-Sheng Chang
BACKGROUND: Chylothorax in children is a relatively rare cause of pleural effusion. However, it is usually a common complication of cardiothoracic operations like open-heart surgery. Other etiologies for chylothorax, such as trauma or malignancy, occur more common in adults and rare in children. To explore the etiologies of chylothorax in children, this study analyzed the pediatric patients that were admitted in to onea medical center. METHODS: We retrospectively reviewed the medical records of the pediatric patients that were admitted to this tertiary transfer center with a diagnosis of chylothorax during the period of 1995 to 2005...
March 2017: BioMedicine
https://www.readbyqxmd.com/read/28474580/etodolac-and-the-risk-of-acute-pancreatitis
#4
Kuan-Fu Liao, Kao-Chi Cheng, Cheng-Li Lin, Shih-Wei Lai
OBJECTIVE: The aim of this study was to explore the association between etodolac use and acute in Taiwan. DESIGN: We designed a case-control study using the database of Taiwan's National Health Insurance. SUBJECTS: In all, 7577 subjects aged 20 years or older with newly diagnosed acute pancreatitis were defined as cases, and 27032 sex-matched and age-matched subjects without acute pancreatitis were defined as controls. The period considered for this study was from 1998 to 2011...
March 2017: BioMedicine
https://www.readbyqxmd.com/read/28474579/effects-of-swimming-exercise-on-nerve-regeneration-in-a-rat-sciatic-nerve-transection-model
#5
Chien-Fu Liao, Tse-Yen Yang, Yung-Hsiang Chen, Chun-Hsu Yao, Tzong-Der Way, Yueh-Sheng Chen
BACKGROUND: Swimming is commonly considered to be an efficient rehabilitation exercise to treat peripheral nerve injury. However, the most effective resistance level and exercise duration is still unclear. We investigated the effects and mechanisms of swimming at various exertion levels in a rat sciatic nerve transection model. METHODS: Sciatic nerve transection rats were randomized into the following four groups based on swimming duration (from the 7th day to the 28th day post-surgery): sedentary control group (SC), S10 group (10 min/3 times/week), S20 group (20 min/3 times/week), and S30 group (30 min/3 times/week) (n = 10 each)...
March 2017: BioMedicine
https://www.readbyqxmd.com/read/28474578/kuei-lu-er-xian-jiao-extract-enhances-bmp-2-production-in-osteoblasts
#6
Min-Huan Wu, Ting-Hsuan Lee, Hsiang-Ping Lee, Te-Mao Li, I-Tee Lee, Po-Chuen Shieh, Chih-Hsin Tang
Osteoporosis is a common skeletal disorder, resulting from an imbalance in bone resorption relative to formation. Bone morphogenetic protein (BMP) is a key regulator in bone formation and osteoblastic differentiation. Hence, compounds that promote BMP expression may be suitable candidates for osteoporosis treatment. This study examined the effects of the traditional Chinese medicinal agent, Kuei-Lu-Er-Xian-Jiao (KLEXJ), on BMP-2 production in osteoblasts. We found that KLEXJ extract promoted osteoblastic differentiation marker ALP activity and increased BMP-2 production; pretreatment with PI3K and Akt inhibitors, or small interfering RNA (siRNA), reduced these effects...
March 2017: BioMedicine
https://www.readbyqxmd.com/read/28474577/association-of-inflammatory-cytokines-with-mortality-in-peritoneal-dialysis-patients
#7
Yao-Lung Liu, Jiung-Hsiun Liu, I-Kuan Wang, Shu-Woei Ju, Tung-Min Yu, I-Ru Chen, Yu-Ching Liu, Chung-Ming Huang, Shih-Yi Lin, Chiz-Tzung Chang, Chiu-Ching Huang
AIMS: Previous study on association between pro-inflammatory cytokines and mortality in PD population is limited. We aimed to investigate here. METHODS: Total 50 patients who underwent incident PD were enrolled in this study. We measured the titers of pro-inflammatory cytokines Interleukin-18(IL-18), Interleukin-6 (IL-6), and Interleukin-1ß (IL-1ß). Study outcomes were all-cause mortality, cardiovascular-related mortality, and infection-caused mortality. Cox-regression model was used...
March 2017: BioMedicine
https://www.readbyqxmd.com/read/27864810/a-case-of-pitt-hopkins-syndrome-presented-with-angelman-like-syndromic-phenotypes
#8
Syuan-Yu Hong, I-Ching Chou, Wei-De Lin, Fuu-Jen Tsai
Pitt-Hopkins syndrome (PTHS), caused by a TCF4 gene mutation, is a condition characterized by intellectual disability and developmental delay, breathing anomalies, epilepsy, and distinctive facial dysmorphism [1]. Its diverse clinical appearance causes pediatricians to confuse it with Angelman syndrome, which is considered one of the family members of Angelman-like syndrome. Herein, we report on a 4 y/o boy with PTHS and discuss its similarities and differences with Angelman syndrome. In doing so we hope to provide a feasible pathway to diagnose rare diseases, especially Angelman-like syndrome...
December 2016: BioMedicine
https://www.readbyqxmd.com/read/27854050/herpes-zoster-correlates-with-pyogenic-liver-abscesses-in-taiwan
#9
Shen Mei-Ling, Liao Kuan-Fu, Tsai Sung-Mao, Lin Ms Cheng-Li, Lai Shih-Wei
OBJECTIVE: The purpose of the paper was to explore the relationship between herpes zoster and pyogenic liver abscesses in Taiwan. METHODS: This was a nationwide cohort study. Using the database of the Taiwan National Health Insurance Program, there were 33049 subjects aged 20-84 years who were newly diagnosed with herpes zoster from 1998 to 2010 that were selected for our study, and they were our herpes zoster group. 131707 randomly selected subjects without herpes zoster were our non-herpes zoster group...
December 2016: BioMedicine
https://www.readbyqxmd.com/read/27854049/facility-evaluation-of-resigned-hospital-physicians-managerial-implications-for-hospital-physician-manpower
#10
Kao-Chi Cheng, Tsung-Lin Lee, Yen-Ju Lin, Chiu-Shong Liu, Cheng-Chieh Lin, Shih-Wei Lai
INTRODUCTION: Turnover of physicians might be responsible for reducing patients' trust and affecting hospital performance. This study aimed to understand physicians' psychological status regarding their hospital work environment and the resources of independent practitioners. METHOD: This was a cross-sectional study with 774 physicians who had resigned from hospitals and were now practicing privately in clinics in Taichung City as its study population. A mail survey with a multidimensional questionnaire was sent to each subject...
December 2016: BioMedicine
https://www.readbyqxmd.com/read/27854048/magnesium-deficiency-and-oxidative-stress-an-update
#11
Anastasia A Zheltova, Maria V Kharitonova, Igor N Iezhitsa, Alexander A Spasov
Magnesium deficiency (MgD) has been shown to impact numerous biological processes at the cellular and molecular levels. In the present review, we discuss the relationship between MgD and oxidative stress (OS). MgD is accompanied by increased levels of OS markers such as lipid, protein and DNA oxidative modification products. Additionally, a relationship was detected between MgD and a weakened antioxidant defence. Different mechanisms associated with MgD are involved in the development and maintenance of OS...
December 2016: BioMedicine
https://www.readbyqxmd.com/read/27854047/neuroprotection-of-gueichih-fuling-wan-on-cerebral-ischemia-reperfusion-injury-in-streptozotocin-induced-hyperglycemic-rats-via-the-inhibition-of-the-cellular-apoptosis-pathway-and-neuroinflammation
#12
Yuh-Fung Chen, Kuo-Jen Wu, Wei-Shih Huang, Yow-Wen Hsieh, Yu-Wen Wang, Huei-Yann Tsai, Ming-Ming Lee
BACKGROUND: Risks of stroke link with complications of hyperglycemia. Gueichih-Fuling-Wan (GFW), according to Chinese Medical Code literature, has the promotion of blood circulation and attenuates the swollen plot. Recent pharmacological studies have pointed out its efficacy in patients with cerebral ischemia or diabetes. Therefore, this study determined whether GFW has the protection against cerebral ischemia/ reperfusion (I/R) injury in streptozotocin (STZ)-induced hyperglycemic rats and LPS-induced inflammation in BV-2 microglial cells...
December 2016: BioMedicine
https://www.readbyqxmd.com/read/27848115/cryotherapy-a-viable-tool-to-remove-broncholiths-under-flexible-bronchoscopy
#13
Sabrina N Campbell, Deepa Lala, Edmundo Rubio
Broncholithiasis is the presence of calcific material within the tracheobronchial tree. Asymptomatic patients can be managed with observation only, whereas symptomatic disease requires surgery, rigid or flexible bronchoscopic removal. Recent reports have shown that flexible bronchoscopy can be a safe and effective option for removal of loose in addition to partially imbedded broncholiths. We present a case of a 65-yearold man with chronic cough that underwent successful cryotherapy assisted bronchoscopic removal of an imbedded broncholith...
December 2016: BioMedicine
https://www.readbyqxmd.com/read/27848114/treating-hepatocellular-carcinoma-with-90-y-bearing-microspheres-a-review
#14
Te-Chun Hsieh, Yu-Chin Wu, Shung-Shung Sun, Kuo-Yang Yen, Chia-Hung Kao
Hepatocellular carcinoma (HCC) is a disease usually diagnosed in its advanced-stage, and is frequently not amenable to curative surgical treatment. Also, HCC is resistant to chemotherapy and less vulnerable to radiation therapy compared to normal hepatic parenchyma. Both of these facts render the efficacy of adjuvant and palliative treatments problematic. Selective internal radiation therapy (SIRT) with (90)Y-bearing microspheres is characterized by preferentially delivering substantially high doses of radiation to a liver tumor dose simultaneously limiting the damage to its non-tumorous cells, providing an opportunity for effective local tumor control and even tumor regression therapy...
November 2016: BioMedicine
https://www.readbyqxmd.com/read/27518399/association-of-different-types-of-liver-disease-with-demographic-and-clinical-factors
#15
Kao-Chi Cheng, Wen-Yuan Lin, Chiu-Shong Liu, Cheng-Chieh Lin, Hsueh-Chou Lai, Shih-Wei Lai
BACKGROUND AND AIM: A metric that predicts the presence of cancer-related liver disease would allow early implementation of treatment. We compared the demographic and clinical characteristics of patients with no evidence of liver disease, with a cancer-associated liver disease, and with a liver disease not associated with cancer. METHODS: Retrospective, hospital-based, cross-sectional study which reviewed the medical records of subjects who underwent health examinations at a Taiwanese hospital from 2000 to 2004 and who had normal levels of amino transaminases...
August 2016: BioMedicine
https://www.readbyqxmd.com/read/27514535/left-subclavian-artery-esophageal-fistula-induced-by-a-paper-star-a-case-report
#16
Chen-Sheng Lin, Cheng-Wen Lin
A subclavian artery-esophageal fistula usually occurs on the right side of an aberrant subclavian artery. It also rarely appears in the site between a non-aberrant subclavian artery and the esophagus due to the ingestion of a foreign body. Upper gastrointestinal bleeding in the case of a subclavian artery-esophageal fistula is rare but often fatal. Here, we report on a 62-year-old male patient with a left subclavian arteryesophageal fistula complicated by hemorrhagic shock. He swallowed a foreign body at a birthday party...
June 2016: BioMedicine
https://www.readbyqxmd.com/read/27514534/epa-or-dha-enhanced-oxidative-stress-and-aging-protein-expression-in-brain-of-d-galactose-treated-mice
#17
Yuan-Man Hsu, Mei-Chin Yin
BACKGROUND: Effects of eicosapentaenoic acid (EPA, 20:5) and docosahexaenoic acid (DHA, 22:6) upon fatty acid composition, oxidative and inflammatory factors and aging proteins in brain of d-galactose (DG) treated aging mice were examined. METHODS: Each fatty acid at 7 mg/kg BW/week was supplied for 8 weeks. Brain aging was induced by DG treatment (100 mg/kg body weight) via daily subcutaneous injection for 8 weeks. RESULTS: DG, EPA and DHA treatments changed brain fatty acid composition...
June 2016: BioMedicine
https://www.readbyqxmd.com/read/27514533/src-is-required-for-migration-phagocytosis-and-interferon-beta-production-in-toll-like-receptor-engaged-macrophages
#18
Ming-Chei Maa, Tzeng-Horng Leu
As an evolutionarily conserved mechanism, innate immunity controls self-nonself discrimination to protect a host from invasive pathogens. Macrophages are major participants of the innate immune system. Through the activation of diverse Toll-like receptors (TLRs), macrophages are triggered to initiate a variety of functions including locomotion, phagocytosis, and secretion of cytokines that requires the participation of tyrosine kinases. Fgr, Hck, and Lyn are myeloid-specific Src family kinases. Despite their constitutively high expression in macrophages, their absence does not impair LPS responsiveness...
June 2016: BioMedicine
https://www.readbyqxmd.com/read/27510965/quercetin-suppresses-cellular-migration-and-invasion-in-human-head-and-neck-squamous-cell-carcinoma-hnscc
#19
Chien-Yi Chan, Chia-Hsien Lien, Ming-Fen Lee, Chun-Yin Huang
Head and neck squamous cell carcinoma (HNSCC) with aberrant epidermal growth factor receptor (EGFR) signaling is often associated with a poor prognosis and a low survival rate. Hence, efficient inhibition of the EGFR signaling-mediated malignancy would improve survival rate. In a previous study, we demonstrated that quercetin appears to be a potent anti-tumorigenic agent through its inhibition of the EGFR/Akt pathway in oral cancer, but its anti-metastatic potential in HNSCC remains unclear [1]. Here, we have hypothesized that quercetin might be effective in metastatic inhibition in EGFR-overexpressing HNSCC cells...
June 2016: BioMedicine
https://www.readbyqxmd.com/read/27510964/bedside-pleuroscopy-in-taiwan-a-great-vision-for-critically-ill-patients-and-intensivists
#20
Hean Ooi
Bedside pleuroscopy can be used in daily practice by medical pulmonologists if a patient cannot tolerate either general anesthesia or being moved to an operating or endoscopy room due to their critical condition. It is a simple and safe technique that rarely has complications. The aim of this review is to summarize recent literatures about bedside pleuroscopy and share our experiences with using it in Taiwan.
June 2016: BioMedicine
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