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Journal of Frailty & Aging

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https://www.readbyqxmd.com/read/29412445/8th-international-conference-on-frailty-and-sarcopenia-research-icfsr-march-1-3-2018-miami-usa-symposia-conference-oral-communications
#1
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2018: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/29412444/frailty-and-neurodegenerative-disease-anticipating-the-future-expanding-the-framework
#2
D M Lyreskog
An array of technologies for preventing and treating age-related neural decline and disease are currently under development. A clear framework for how to identify groups in need of such inventions is needed. An encompassing concept of frailty could provide a solid basis for such purposes. Concepts of frailty, including physical and cognitive frailty, are currently applied in clinical settings, and in research and development. The terminology facilitates identifying processes of age-related physical and cognitive decline...
2018: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/29412443/muscle-quality-improves-with-extended-high-intensity-resistance-training-after-hip-fracture
#3
R A Briggs, J R Houck, M J Drummond, J M Fritz, P C LaStayo, R L Marcus
BACKGROUND: Muscle mass deficits endure after hip fracture. Strategies to improve muscle quality may improve mobility and physical function. It is unknown whether training after usual care yields muscle quality gains after hip fracture. OBJECTIVES: To determine whether muscle quality improves after hip fracture with high-intensity resistance training and protein supplementation. DESIGN: Case series. SETTING: University of Utah Skeletal Muscle Exercise Research Facility...
2018: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/29412442/preliminary-study-on-prevalence-and-associated-factors-with-sarcopenia-in-a-geriatric-hospitalized-rehabilitation-setting
#4
K Pongpipatpaiboon, I Kondo, K Onogi, S Mori, K Ozaki, A Osawa, H Matsuo, N Itoh, M Tanimoto
The reported prevalence of sarcopenia has shown a wide range, crucially based on the diagnostic criteria and setting. This cross-sectional study evaluated the prevalence of sarcopenia and sought to identify factors associated with sarcopenia on admission in a specialized geriatric rehabilitation setting based on the newly developed the Asian Working Group for Sarcopenia algorithm. Among 87 participants (mean age, 76.05 ± 7.57 years), 35 (40.2%) were classified as showing sarcopenia on admission. Prevalence was high, particularly among participants ≥80 years old, with tendencies toward lower body mass index, smoking habit, lower cognitive function, and greater functional impairment compared with the non-sarcopenic group...
2018: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/29412441/impact-of-sarcopenia-on-one-year-mortality-among-older-hospitalized-patients-with-impaired-mobility
#5
M Pourhassan, K Norman, M J Müller, R Dziewas, R Wirth
OBJECTIVES: However, the information regarding the impact of sarcopenia on mortality in older individuals is rising, there is a lack of knowledge concerning this issue among geriatric hospitalized patients. Therefore, aim of the present study was to investigate the associations between sarcopenia and 1-year mortality in a prospectively recruited sample of geriatric inpatients with different mobility and dependency status. DESIGN AND SETTING: Sarcopenia was diagnosed using the criteria of the European Working Group on Sarcopenia in Older People (EWGSOP)...
2018: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/29412440/precipitants-of-delirium-in-older-inpatients-admitted-in-surgery-for-post-fall-hip-fracture-an-observational-study
#6
E Levinoff, A Try, J Chabot, L Lee, D Zukor, O Beauchet
BACKGROUND: Hip fractures precipitate several acute adverse outcomes in elderly people, thus leading to chronic adverse outcomes. OBJECTIVES: The objective of our study was to examine the clinical characteristics associated with incident delirium in community dwelling elderly individuals who have a hip fracture. DESIGN: Retrospective observational cohort study. SETTING: Data was collected from an academic tertiary hospital affiliated with McGill University...
2018: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/29412439/new-simplified-screening-method-for-postprandial-hypotension-in-older-people
#7
R Abbas, A Tanguy, D Bonnet-Zamponi, R Djedid, A Lounis, M-L Gaubert-Dahan
BACKGROUND: Postprandial hypotension (PPH) is an important disorder in the older people that remain underdiagnosed. The reference PPH diagnostic method is too demanding, because blood pressure (BP) needs to be measured 8 times in 2 hours. OBJECTIVES: Our primary objective was to define a new simplified PPH diagnostic method and to evaluate its performances. DESIGN: We conducted a cross-sectional study. SETTING: Two geriatric rehabilitation units in France...
2018: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/29412438/the-vicious-cycle-of-myostatin-signaling-in-sarcopenic-obesity-myostatin-role-in-skeletal-muscle-growth-insulin-signaling-and-implications-for-clinical-trials
#8
L A Consitt, B C Clark
The age-related loss of skeletal muscle (sarcopenia) is a major health concern as it is associated with physical disability, metabolic impairments, and increased mortality. The coexistence of sarcopenia with obesity, termed 'sarcopenic obesity', contributes to skeletal muscle insulin resistance and the development of type 2 diabetes, a disease prevalent with advancing age. Despite this knowledge, the mechanisms contributing to sarcopenic obesity remain poorly understood, preventing the development of targeted therapeutics...
2018: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/29412437/an-international-position-statement-on-the-management-of-frailty-in-diabetes-mellitus-summary-of-recommendations-2017
#9
A J Sinclair, A Abdelhafiz, T Dunning, M Izquierdo, L Rodriguez Manas, I Bourdel-Marchasson, J E Morley, M Munshi, J Woo, B Vellas
AIM: The International Position Statement provides the opportunity to summarise all existing clinical trial and best practice evidence for older people with frailty and diabetes. It is the first document of its kind and is intended to support clinical decisions that will enhance safety in management and promote high quality care. METHODS: The Review Group sought evidence from a wide range of studies that provide sufficient confidence (in the absence of grading) for the basis of each recommendation...
2018: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/29412436/implications-of-icd-10-for-sarcopenia-clinical-practice-and-clinical-trials-report-by-the-international-conference-on-frailty-and-sarcopenia-research-task-force
#10
B Vellas, R A Fielding, C Bens, R Bernabei, P M Cawthon, T Cederholm, A J Cruz-Jentoft, S Del Signore, S Donahue, J Morley, M Pahor, J-Y Reginster, L Rodriguez Mañas, Y Rolland, R Roubenoff, A Sinclair, M Cesari
Establishment of an ICD-10-CM code for sarcopenia in 2016 was an important step towards reaching international consensus on the need for a nosological framework of age-related skeletal muscle decline. The International Conference on Frailty and Sarcopenia Research Task Force met in April 2017 to discuss the meaning, significance, and barriers to the implementation of the new code as well as strategies to accelerate development of new therapies. Analyses by the Sarcopenia Definitions and Outcomes Consortium are underway to develop quantitative definitions of sarcopenia...
2018: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/29165542/measuring-frailty-among-older-people-further-evaluation-of-the-brody-frailty-index
#11
U Jakobsson
BACKGROUND AND OBJECTIVE: The study aimed to evaluate the predictive validity of the Brody self-report frailty index among older people. Design, setting and measurements: A longitudinal cohort study (2-years) conducted in Sweden, which included 1141 respondents, aged 65-103 years. Data were collected during 2011-2013 through a postal questionnaire with questions about demographic data, living conditions, self-reported health, ADL dependency (ADL-staircase) and frailty (the Brody frailty index)...
2017: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/29165541/frailty-exists-in-younger-adults-admitted-as-surgical-emergency-leading-to-adverse-outcomes
#12
R Smart, B Carter, J McGovern, S Luckman, A Connelly, J Hewitt, T Quasim, S Moug
BACKGROUND: Frailty is prevalent in the older adult population (≥65 years of age) and results in adverse outcomes in the emergency general surgical population. OBJECTIVE: To determine whether frailty exists in the younger adult emergency surgical population (<65 years) and what influence frailty may have on patient related outcomes. DESIGN: Prospective observational cohort study. SETTING: Emergency general surgical admissions...
2017: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/29165540/mobile-application-removes-societal-barriers-to-p4-medicine
#13
J-P Michel
The overlap between one innovative paradigm (P4 medicine: predictive, personalized, participatory and preventive) and another (a new definition of "Healthy ageing") is fertile ground for new technologies; a new mobile application (app) that could broaden our scientific knowledge of the ageing process and help us to better analyse the impact of possible interventions in slowing the ageing decline. A novel mobile application is here presented as a game including questions and tests will allow in 10 minutes the assessment of the following domains: robustness, flexibility (lower muscle strength), balance, mental and memory complaints, semantic memory and visual retention...
2017: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/29165539/management-of-musculoskeletal-conditions-in-rural-south-australia-a-randomised-controlled-trial
#14
E Dent, E Hoon, J Karnon, A Kitson, J Dollard, J Newbury, G Harvey, T Gill, J Beilby
With age, the prevalence of musculoskeletal conditions increases markedly. This rural-based study determined the benefits of two approaches for managing musculoskeletal conditions: a multiple-component 'Self-management Plus' intervention, and usual care. The intervention combined self-management education with physical activity and health professional support. 6-month outcomes included: Clinical Global Impression-Improvement Scale (CGI-IS) and Quality of Life (QoL). A total of 145 people were recruited; mean (SD) age was 66...
2017: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/29165538/augmented-reality-sustaining-autonomous-way-finding-in-the-community-for-older-persons-with-cognitive-impairment
#15
K Sejunaite, C Lanza, S Ganders, A Iljaitsch, M W Riepe
BACKGROUND: Impairment of autonomous way-finding subsequent to a multitude of neurodegenerative and other diseases impedes independence of older persons and their everyday activities. OBJECTIVE: It was the goal to use augmented reality to aid autonomous way-finding in a community setting. DESIGN: A spatial map and directional information were shown via head-up display to guide patients from the start zone on the hospital campus to a bakery in the nearby community...
2017: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/29165537/frailty-is-not-associated-with-mistreatment
#16
S D Piña-Escudero, J M A García-Lara, J A Avila-Funes
Muscle Frailty has been previously associated with increased vulnerability for adverse health-related outcomes that could lead to social consequences such as mistreatment. The aim of this cross-sectional study is to determine the association between frailty and mistreatment in 852 community-dwelling persons aged 70 or older. Mistreatment was defined as one positive answer in the Geriatric Mistreatment Scale and frailty was used as a continuum where the greater number of positive criteria according to Fried et al...
2017: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/29165536/reference-values-for-knee-extension-strength-obtained-by-hand-held-dynamometry-from-apparently-healthy-older-adults-a-meta-analysis
#17
R W Bohannon
Normative reference values for knee extension strength obtained by hand-held dynamometry from adults 60 to 79 years were derived using summary data from 3 studies. The studies, which were identified through PubMed and a hand-search, contributed data from between 3 and 29 individuals for each age, gender, and side stratum. Meta-analysis was employed to consolidate knee extension strength data. Strength, normalized against body weight, ranged 35.6% for the nondominant side of 70 to 79 year old women to 48.8% for the nondominant side of 60 to 69 year old men...
2017: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/29165535/the-feasibility-of-standardised-geriatric-assessment-tools-and-physical-exercises-in-frail-older-adults
#18
A D Jadczak, N Mahajan, R Visvanathan
Geriatric assessment tools are applicable to the general geriatric population; however, their feasibility in frail older adults is yet to be determined. The study aimed to determine the feasibility of standardised geriatric assessment tools and physical exercises in hospitalised frail older adults. Various assessment tools including the FRAIL Screen, the Charlson Comorbidity Index, the SF-36, the Trail Making Test (TMT), the Rapid Cognitive Screen, the Self Mini Nutritional Assessment (MNA-SF) and the Lawton iADL as well as standard physical exercises were assessed using observational protocols...
2017: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/29165534/various-diagnostic-measures-of-frailty-as-predictors-for-falls-weight-change-quality-of-life-and-mortality-among-older-finnish-men
#19
N M Perttila, K H Pitkala, H Kautiainen, R Tilvis, T Stranberg
BACKGROUND: Frailty predisposes individuals to a variety of complications. However, there is no consensus on the definition of frailty. OBJECTIVES: To examine whether various frailty measures are equivalent in identifying the same individuals as being frail and whether the measures also predict similar outcomes. DESIGN, SETTING AND PARTICIPANTS: The Helsinki Businessmen Study cohort, which is a long-term observational study of men born in 1919-1934, was used as the population...
2017: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/29165533/muscle-quality-strength-and-lower-extremity-physical-performance-in-the-baltimore-longitudinal-study-of-aging
#20
N Chiles Shaffer, E Fabbri, L Ferrucci, M Shardell, E M Simonsick, S Studenski
BACKGROUND: Muscle quality is defined as the force generated by each volumetric unit of muscle tissue. No consensus exists on an optimal measure of muscle quality, impeding comparison across studies and implementation in clinical settings. It is unknown whether muscle quality measures that rely on complex and expensive tests, such as isokinetic dynamometry and computerized tomography correlate with lower extremity performance (LEP) any better than measures derived from simpler and less expensive tests, such as grip strength (Grip) and appendicular lean mass (ALM) assessed by DXA...
2017: Journal of Frailty & Aging
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