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Basic and Clinical Neuroscience

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https://www.readbyqxmd.com/read/28781733/median-nerve-cavernous-hemangioma
#1
Mohammed Al-Garnawee, Marwan Najjar
Hemangiomas of the median nerve are extremely rare; only 12 cases have been reported in the literature. We discuss a patient who presented with paresthesia and pain along the distribution of the left median nerve secondary to a cavernoma of the proximal part of the nerve as suspected on MRI scan. Total removal of the mass was achieved with immediate relief of the symptoms and no neurologic deficit. We conclude that despite being quite rare, the diagnosis of occult vascular lesions of peripheral nerves such as the median nerve, should be considered, especially when other common pathologies are excluded...
May 2017: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/28781732/protective-effects-of-cyperus-rotundus-extract-on-amyloid-%C3%AE-peptide-1-40-induced-memory-impairment-in-male-rats-a-behavioral-study
#2
Mehdi Mehdizadeh, Fataneh Hashem Dabaghian, Asie Shojaee, Nima Molavi, Zahra Taslimi, Ronak Shabani, Sara Soleimani Asl
INTRODUCTION: The Alzheimer Disease (AD) is the most common form of dementia that leads to memory impairment. As the oxidative stress plays an important role in AD pathogenesis, the current study aimed at examining the protective effects of Cyperus Rotundus as an antioxidant on amyloid β (Aβ)-induced memory impairment. METHODS: Twenty-eight Wistar male rats received intrahippocampal (IHP) injection of the Aβ (1-40) and C. rotundus (400 mg/kg, intraperitoneally)...
May 2017: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/28781731/neuropsychological-functioning-in-obsessive-compulsive-washers-drug-naive-without-depressive-symptoms
#3
Ali Akbar Saremi, Seyed Vahid Shariat, Mohammad Ali Nazari, Behrooz Dolatshahi
INTRODUCTION: Obsessive-Compulsive Disorder (OCD) is a complex and heterogeneous neuropsychiatric syndrome. Contamination obsessions and washing/cleaning compulsions are the most frequent clinical OCD subtypes. The current study aimed at examining the neuropsychological impairments in drug-naive obsessive-compulsive (OC) washers without depressive symptoms and their association with the severity of symptoms. METHODS: In the current causal-comparative study, 35 patients with diagnostic and statistical mental disorders class (DSM)-IV diagnosed with washing-subtype OCD and 35 healthy subjects were selected by the convenience sampling method and evaluated by computerized neuropsychology battery and clinical tests as Stroop Color-Word Test (SCWT), Wisconsin Card Sorting Test (WCST), Go/No-Go Test, Digits Forward (DF), Digits Backward (DB), Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), and General Health Questionnaire (GHQ)-28...
May 2017: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/28781730/executive-functions-in-students-with-depression-anxiety-and-stress-symptoms
#4
Bita Ajilchi, Vahid Nejati
INTRODUCTION: This study aimed to investigate and compare the executive functions of students with depression, anxiety, and stress symptoms with those functions in healthy ones. METHODS: This study was a comparative and non-clinical analysis. The study population comprised all students of Shahid Beheshti University, Tehran, Iran. A total of 448 students were recruited using convenience sampling method. They were also screened using the Depression Anxiety Stress Scales (DASS) test comprising 21 items...
May 2017: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/28781729/the-modulatory-role-of-orexin-1-receptor-in-ca1-on-orofacial-pain-induced-learning-and-memory-deficits-in-rats
#5
Razieh Kooshki, Mehdi Abbasnejad, Saeed Esmaeili-Mahani, Maryam Raoof
INTRODUCTION: Cognitive impairment is commonly associated with pain. The modulatory role of orexin 1 receptor (OX1R) in pain pathways as well as learning and memory processes is reported in several studies. The current study was designed to investigate the possible role of CA1-hippocampal OX1R on spatial learning and memory of rats following capsaicin-induced orofacial pain. METHODS: Orofacial pain was induced by subcutaneous intra lip injection of capsaicin (100 μg)...
May 2017: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/28781728/effect-of-play-based-therapy-on-meta-cognitive-and-behavioral-aspects-of-executive-function-a-randomized-controlled-clinical-trial-on-the-students-with-learning-disabilities
#6
Samaneh Karamali Esmaili, Narges Shafaroodi, Afsoon Hassani Mehraban, Akram Parand, Masoume Zarei, Saeed Akbari-Zardkhaneh
INTRODUCTION: Although the effect of educational methods on executive function (EF) is well known, training this function by a playful method is debatable. The current study aimed at investigating if a play-based intervention is effective on metacognitive and behavioral skills of EF in students with specific learning disabilities. METHODS: In the current randomized, clinical trial, 49 subjects within the age range of 7 to 11 years with specific learning disabilities were randomly assigned into the intervention (25 subjects; mean age 8...
May 2017: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/28781727/cross-state-dependent-learning-interaction-between-scopolamine-and-morphine-in-mice-the-role-of-dorsal-hippocampus
#7
Morteza Maleki, Majid Hassanpour-Ezatti, Majid Navaeian
INTRODUCTION: The current study aimed at investigating the existence of the cross state-dependent learning between morphine and scopolamine (SCO) in mice by passive avoidance method, pointing to the role of CA1 area. METHODS: The effects of pre-training SCO (0.75, 1.5, and 3 μg, Intra-CA1), or morphine (1, 3, and 6 mg/kg, intraperitoneal (i.p.) was evaluated on the retrieval of passive avoidance learning using step-down task in mice (n=10). Then, the effect of pretest administration of morphine (1...
May 2017: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/28781726/the-anti-parkinsonism-effects-of-katp-channel-blockade-in-the-6-hydroxydopamine-induced-animal-model-the-role-of-oxidative-stress
#8
Hossein Piri, Hashem Haghdoost-Yazdi, Negin Fraidouni, Tahereh Dargahi, Mohamadhosein Yaghoubidoust, Abbas Azadmehr
INTRODUCTION: Studies suggest that ATP-sensitive potassium (KATP) channels are a potential pharmacotherapeutic target for neuroprotection in neurodegenerative diseases. The current study aimed at evaluating the effect of pretreatment with glibenclamide (Glib) and B vitamins supplement on the severity of behavioral symptoms in 6-hydroxydopamine (OHDA)-induced Parkinsonism. Also malondialdehyde (MDA) concentration was measured in the blood and brain suspensions to find probable neuroprotective mechanism of Glib...
May 2017: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/28781725/the-impact-of-synovial-nf-%C3%AE%C2%BAb-activation-on-apoptosis-pattern-change-during-adjuvant-induced-inflammation
#9
Sahar Golabi, Jalal Zaringhalam, Homa Manaheji
INTRODUCTION: Apoptosis dysregulation plays a substantial role in the pathophysiology of chronic inflammation and its related symptoms such as edema. Regulation of NF-κB activation is involved in apoptosis pattern change. The current study aimed at verifying the effects of local inflammation on edema and changes in apoptotic markers, and investigating the possible role of NF-κB in apoptosis pattern change during different stages of complete Freund's adjuvant (CFA)-induced knee arthritis in rats...
May 2017: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/28540000/response-of-the-pre-oriented-goal-directed-attention-to-usual-and-unusual-distractors-a-preliminary-study
#10
Golnaz Baghdadi, Farzad Towhidkhah, Reza Rostami, Mohsen Raza
INTRODUCTION: In this study, we investigated the distraction power of the unusual and usual images on the attention of 20 healthy primary school children. METHODS: Our study was different from previous ones in that the participants were asked to fix the initial position of their attention on a predefined location after being presented with unusual images as distractors. The goals were presented in locations, which were far from the attraction basin of distractors...
March 2017: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/28539999/assessment-of-executive-functions-in-methamphetamine-addicted-individuals-emphasis-on-duration-of-addiction-and-abstinence
#11
Majid Farhadian, Malahat Akbarfahimi, Peyman Hassani Abharian, Seyedeh Golaleh Hosseini, Susan Shokri
INTRODUCTION: Several studies have conducted on impairments of executive functions in individuals with methamphetamine addiction; however, only a few have investigated the relationship between executive functions and duration of addiction or abstinence. This study was designed to assess the executive functions in methamphetamine-addicted individuals in relation to the duration of addiction or abstinence. METHODS: A total of 161 subjects aged between 20 and 45 years were categorized into three subgroups: currently abusing (n=41), abstinent (n=60), and control healthy individuals (n=60)...
March 2017: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/28539998/correlation-between-cannabidiol-induced-reduction-of-infarct-volume-and-inflammatory-factors-expression-in-ischemic-stroke-model
#12
Sepideh Khaksar, Mohammad Reza Bigdeli
INTRODUCTION: Recent studies demonstrated that cannabidiol had neuroprotective property. There is some evidence about effective role of cannabidiol in reduction of ischemic damages. It has been reported that infarct size is influenced by various factors after MCAO, including inflammatory factors. The aim of the present study was to evaluate the effect of cannabidiol on infarction volume and correlation of infarct size with tumor necrosis factor receptor 1 (TNFR1), and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) expression...
March 2017: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/28539997/interaction-between-the-cannabinoid-and-vanilloid-systems-on-anxiety-in-male-rats
#13
Nafiseh Faraji, Alireza Komaki, Iraj Salehi
INTRODUCTION: Previous studies have shown that the cannabinoid system is involved in anxiety. In addition, transient receptor potential vanilloid type-1 (TRPV1) channels are new targets for the development of anxiolytics. The present study investigated the possible interaction between the cannabinoid and vanilloid systems on anxiety-like behavior in rats. METHODS: Four different groups of male Wistar rats received intraperitoneal (IP) injections of (1) vehicle (DMSO+saline), (2) cannabinoid receptor agonist WIN55212-2 (WIN) (1 mg/kg), (3) TRPV1 receptor antagonist capsazepine (CPZ) (5 mg/kg), or (4) combined WIN (1 mg/kg) and CPZ (5 mg/kg) treatment 30 minutes before testing in the elevated plus maze...
March 2017: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/28539996/transient-inactivation-of-shell-part-of-nucleus-accumbens-inhibits-and-exacerbates-stress-induced-metabolic-alterations-in-wistar-rats
#14
Mina Ranjbaran, Hassan Aghaei, Vahdat Hajihoseinlou, Hedayat Sahraei, Katayoon Ranjbaran
INTRODUCTION: The role of different parts of the extended amygdala in metabolic signs of stress is not well understood. In the present study, we decided to evaluate the impact of the shell part of nucleus accumbens (NAc) on metabolic disturbance induced by electro foot shock stress using transient inactivation method in the rat. METHODS: Male Wistar rats (W: 230-250 g) were canuulated unilaterally in the shell part of nucleus accumbens and left one week for recovery...
March 2017: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/28539995/the-effect-of-luteinizing-hormone-reducing-agent-on-anxiety-and-novel-object-recognition-memory-in-gonadectomized-rats
#15
Paria Arfa-Fatollahkhani, Arezo Nahavandi, Hossein Abtahi, Shabnam Anjidani, Sahar Borhani, Seyed Behnam Jameie, Mohammad Shabani, Saeed Mehrzadi, Ali Shahbazi
INTRODUCTION: Mood disorders such as anxiety and depression are common following menopause and andropause. Lack of sex steroid hormones is suggested as the primary cause of these disturbances. The level of luteinizing hormone (LH) would also rise 3-4 times than normal in these people. The potential effects of LH on mood and cognitive symptoms following menopause and andropause are still unknown. This study aimed to investigate the effect of increased LH on novel object discrimination (NOD) memory and anxiety like behavior in gonadectomized rats...
March 2017: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/28539994/the-prevalence-of-restless-legs-syndrome-in-patients-undergoing-hemodialysis-a-systematic-review-and-meta-analysis-study
#16
REVIEW
Reza Ghanei Gheshlagh, Mohammad Farajzadeh, Mozhdeh Zarei, Vajiheh Baghi, Sahar Dalvand, Kourosh Sayehmiri
INTRODUCTION: Restless legs syndrome is a sensory-motor disorder that causes sleep disorder. The syndrome in patients undergoing hemodialysis associates with depression, sleep deprivation, performance disorder, day fatigue, excessive daytime sleepiness, stress, anxiety, and higher risk of cardiovascular diseases. The objective of this systematic meta-analysis study was to estimate prevalence of restless legs syndrome in patients undergoing hemodialysis. METHODS: Twenty-six relevant articles published between 2000 and 2015 indexed in Iranian (MagIran and IranMedex) and international databases (SID, Google Scholar, ScienceDirect, PubMed, Pre Quest, and Scopus) were selected...
March 2017: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/28539993/effectiveness-of-non-pharmacological-interventions-on-stereotyped-and-repetitive-behaviors-of-pre-school-children-with-autism-a-systematic-review
#17
REVIEW
Hadi Zarafshan, Maryam Salmanian, Soudeh Aghamohammadi, Mohammad Reza Mohammadi, Seyed-Ali Mostafavi
INTRODUCTION: The present study aimed to review the literature on non-pharmacological interventions used to treat stereotyped and repetitive behaviors by a systematic method. METHODS: Two authors independently performed a search strategy on Medline/PubMed, Scopus and PsycINFO on English articles published up to April 23, 2014 with relevant search keywords. We also reviewed the bibliographies of retrieved articles and conference proceedings to obtain additional citations and references...
March 2017: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/28446954/comment-on-the-effect-of-endocannabinoid-system-on-rat-behavior
#18
COMMENT
Ali Roohbakhsh
No abstract text is available yet for this article.
January 2017: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/28446953/neuroprotective-effects-of-exercise-on-brain-edema-and-neurological-movement-disorders-following-the-cerebral-ischemia-and-reperfusion-in-rats
#19
Nabi Shamsaei, Soheila Erfani, Masoud Fereidoni, Ali Shahbazi
INTRODUCTION: Cerebral ischemia and reperfusion causes physiological and biochemical changes in the neuronal cells that will eventually lead to cell damage. Evidence indicates that exercise reduces the ischemia and reperfusion-induced brain damages in animal models of stroke. In the present study, the effect of exercise preconditioning on brain edema and neurological movement disorders following the cerebral ischemia and reperfusion in rats was investigated. METHODS: Twenty-one adult male wistar rats (weighing 260-300 g) were randomly divided into three groups: sham operated, exercise plus ischemia, and ischemia group (7 rats per group)...
January 2017: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/28446952/the-effect-of-group-based-occupational-therapy-on-performance-and-satisfaction-of-stroke-survivors-pilot-trail-neuro-occupational-view
#20
Maryam Mehdizadeh, Afsoon Hassani Mehraban, Roohollah Zahediyannasab
INTRODUCTION: Stroke imposes limitations on performing activities of daily living (ADL) and their level. Different therapeutic approaches are used for improving the level of performance after a stroke. This study was performed with the aim of evaluating the effect of group-based occupational therapy on improving the performance of ADL and satisfaction of its performance in patients with chronic strokes. METHODS: Fourteen chronic stroke patients with the mean age of 52 years participated in the study...
January 2017: Basic and Clinical Neuroscience
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