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Journal of Exercise Nutrition & Biochemistry

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https://www.readbyqxmd.com/read/30343562/the-kv7-channel-activator-retigabine-induces-vasorelaxation-via-an-endothelial-independent-pathway-in-male-mouse-aorta
#1
Hyun Namgoong, Chaeeun Cho, Sewon Lee
PURPOSE: Previous studies have indicated that Kv7 channels have an important role in the regulation of blood vessel reactivity, including in the coronary, renal, and cerebral arteries. The present studies examined whether Kv7 channels regulated vascular reactivity in the mouse aorta and investigated the mechanisms involved in the reactivity. METHODS: Wild-type (WT) male C57BL/6 mice, between 10 and 15 weeks old, were used in this study. The vascular function of the aorta in WT male mice was assessed by using a pin myography system (Model 620; DMT, Denmark)...
September 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/30343561/treadmill-running-suppresses-the-vulnerability-of-dopamine-d2-receptor-deficiency-to-obesity-and-metabolic-complications-a-pilot-study
#2
Jinkyung Cho, Donghyun Kim, Jungmoon Jang, Jeonghyeon Kim, Hyunsik Kang
PURPOSE: To investigate the effect of treadmill running on D2R deficiency related susceptibility to high fat diet (HFD )-induced obesity and its metabolic complications. METHODS: D2R-/- and +/- mice were obtained by backcrossing D2R+/- heterozygotes on wild type (WT) littermates (C57BL/6J background) for >10 generations. Mice were randomly assigned to 1) WT mice with standard chow (SC) (WT+SC); 2) WT mice with high-fat diet (WT+HFD); 3) WT mice with high-fat diet plus exercise (WT+HFD+EX), 4) heterozygous (HET) D2R mice with SC (HET+SC); 5) heterozygous D2R mice with HFD (HET+HFD); and 6) heterozygous D2R mice with HFD plus exercise (HET+HFD+EX)...
September 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/30343560/the-ameliorating-effect-of-exercise-on-long-term-memory-impairment-and-dendritic-retraction-via-the-mild-activation-of-amp-activated-protein-kinase-in-chronically-stressed-hippocampal-ca1-neurons
#3
Yea-Hyun Leem, Hyukki Chang
PURPOSE: Chronic stress affects the neuronal architecture of hippocampal subfields including the Cornu Ammonis 1 (CA1) region, which governs long-term memory. Exercise exerts a beneficial effect on memory improvement via hippocampal AMP-activated protein kinase (AMPK) activation. However, the relationship between the two phenomena is poorly understood. This study used animal and cell culture experimental systems to investigate whether chronic stress-induced impairment of memory consolidation and maladaptation of the neuronal architecture in the hippocampal CA1 area is prevented by regular exercise through AMPK activation...
September 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/30343556/weight-loss-practice-nutritional-status-bone-health-and-injury-history-a-profile-of-professional-jockeys-in-korea
#4
Soeun Jeon, Kyungho Cho, Gina Ok, Sukho Lee, Hyon Park
PURPOSE: The purpose of this study was to investigate the impact of weight loss practices on nutritional status, bone health, and injury history among Korean professional jockeys. METHODS: Forty-three male jockeys completed a questionnaire to assess their weight loss practices. Of these, 10 jockeys were selected for in-depth assessment of their nutritional status, bone health, and injury history. RESULTS: The questionnaires revealed that 81...
September 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/30343555/angiogenesis-focusing-on-the-effects-of-exercise-in-aging-and-cancer
#5
Seong-Eun Kwak, Ji-Hyun Lee, Didi Zhang, Wook Song
PURPOSE: Although it is known that exercise induces angiogenesis, a clear mechanism has remained elusive due to various experimental limitations. This review presents the current status of angiogenesis-related experiments and future directions of experimentation in relation to exercise, aging, and cancer. METHODS: We conducted a PubMed search of the available literature to identify reported exercise related changes of angiogenic factors obtained in vitro using C2C12 cells and endothelial cells, and in vivo using animal experiments and in clinical studies...
September 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/30343554/the-effects-of-coenzyme-q10-on-oxidative-stress-and-heat-shock-proteins-in-rats-subjected-to-acute-and-chronic-exercise
#6
Ragip Pala, Fahrettin Beyaz, Mehmet Tuzcu, Besir Er, Nurhan Sahin, Vedat Cinar, Kazim Sahin
PURPOSE: The aim of the study was to determine the effects of dietary CoQ10 on serum biochemical parameters, lipid peroxidation, and HSP expression in the liver and slow-twitch muscles (soleus and gastronemius deep portion) of exercise-trained rats. METHODS: A total of 42 Wistar albino rats were divided into six groups: 1) Control, 2) Coenzyme Q10 (CoQ10), 3) Chronic Exercise (CE), 4) CE + CoQ10, 5) Acute Exercise (AE), and 6) AE + CoQ10. The rats were subjected to the running test 5 days a week for 6 weeks after which CoQ10 was administered via the diet...
September 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/30343553/ginseng-berry-extract-increases-nitric-oxide-level-in-vascular-endothelial-cells-and-improves-cgmp-expression-and-blood-circulation-in-muscle-cells
#7
Cho In-Ho, Kang Byung-Woo, Park Yun-Jae, Lee Han-Joo, Park Sok, Lee Namju
PURPOSE: The purpose of this study was to determine whether ginseng berry extract improves blood circulation by regulating vasodilator expression in exposed to tumor necrosis factor alpha (TNF-α)-exposed endothelial cells and muscle cells. METHODS: Nitric oxide (NO) and cGMP levels in human umbilical vein endothelial cells (HUVECs) and A7r5 cells exposed to ginseng berry extract were investigated. Based on the in vitro results, healthy participants were treated with ginseng berry extract for 4 weeks and then a non-invasive vascular screening device was used to confirm the improvement of blood circulation...
September 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/30343552/new-insight-of-high-intensity-interval-training-on-physiological-adaptation-with-brain-functions
#8
Lee Min Chul, Lee Sung Ki, Jung Suk Yool, Moon Hyung Hoon
PURPOSE: Exercise effectively enhances physiological adaptation, performance, and health-related markers in healthy individuals and diseased populations. However, the type and amount of optimal exercise remain controversial. High-intensity interval training (HIIT) took the top spot in the American College of Sports Medicine worldwide survey on fitness trends in 2018. METHODS: We review information on the effect of HIIT on physiological adaptation and the novel role on brain functions...
September 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/30149426/age-and-sex-related-differences-in-myosin-heavy-chain-isoforms-and-muscle-strength-function-and-quality-a-cross-sectional-study
#9
Seung-Lyul Oh, Sang Hoon Yoon, Jae-Young Lim
PURPOSE: Declining muscle strength and function are hallmarks of the aging process. This study aimed to determine sex-related differences in myosin heavy chain (MHC) isoforms and muscle mass, strength, and quality with aging. METHODS: This cross-sectional study recruited 53 healthy participants (32 men, 21 women) aged 20-85 years who were divided into four groups: young men (n=17, YM, 29.23±4.51), older men (n=15, OM, 71.87±3.42), young women (n=11, YW, 29.64±4...
June 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/30149425/role-of-l-carnitine-and-oleate-in-myogenic-differentiation-implications-for-myofiber-regeneration
#10
Hojun Lee, Jae-Young Lim, Seung-Jun Choi
PURPOSE: Myogenic progenitors play a critical role in injury-induced myofiber regeneration. The purpose of this study was to characterize the effects of oleate and L-carnitine on the overall behavior of proliferating myogenic progenitors (myoblasts) and its link to the mitochondrial biogenic process. METHODS: C2C12 myoblasts were cultured either with no treatment, oleate, L-carnitine, or their mixture. Proliferating myoblasts were investigated under a phase-contrast microscope...
June 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/30149424/smallanthus-sonchifolius-leaf-attenuates-neuroinflammation
#11
Suji Baek, Nan Hee Choi, Kang-Pa Lee, Hyunjhung Jhun, Jisu Kim
PURPOSE: Yacon, Smallanthus sonchifolius, has anti-hypertensive, anti-inflammatory, and anti-cancer potential. However, its neuroprotective and anti-neuroinflammatory effects are unknown. Moreover, activation of microglia has been considered a mechanism in the development of Alzheimer's disease. Therefore, the aim of this study was to determine the neuroprotective effects of an ethanolic yacon leaf extract (YLE) on lipopolysaccharide (LPS)-induced neuroinflammation in vitro and in vivo...
June 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/30149423/non-exercise-activity-thermogenesis-neat-a-component-of-total-daily-energy-expenditure
#12
Nana Chung, Mi-Young Park, Jisu Kim, Hun-Young Park, Hyejung Hwang, Chi-Ho Lee, Jin-Soo Han, Jaemoo So, Jonghoon Park, Kiwon Lim
PURPOSE: The purpose of this review is to promote awareness of non-exercise activity thermogenesis (NEAT) as a new strategy to increase energy expenditure, and to manage obesity. METHODS: The content of this review is based on a literature search of PubMed and the Google Scholar search engine, using the search terms obesity, energy expenditure, non-exercise activity thermogenesis (NEAT), and sitting disease. RESULTS: Daily energy expenditure is of great interest because most obese individuals have no exercise activity-related thermogenesis (EAT); thus their physical activity-related energy expenditure (PEE) is comprised almost entirely of NEAT...
June 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/30149422/the-effects-of-the-elastin-polymorphisms-on-carotid-intima-media-thickness-in-women-aged-30-70
#13
Seung-Taek Lim, Jin-Kee Park, Sang-Hyuk Park, Eun-Jae Lee, Woo-Nam Kim, Seok-Ki Min
PURPOSE: Elastin is one of the major determinants of arterial distensibility of large blood vessels that forms the principal component of elastic fibers from the media of arteries. However, the association between elastin(ELN) genotype and vascular function is still unclear. METHODS: 120women were recruited from the Saha-gu (Busan, Korea) Community Center. Measurements of body composition and vascular function included carotid intima-media thickness (CIMT), carotid artery luminal diameter (CLD), minimum (diastolic) artery luminal diameter (CLDmin) and maximum (systolic) artery luminal diameter (CLDmax)...
June 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/30149421/irisin-response-to-downhill-running-exercise-in-humans
#14
Yoshifumi Tsuchiya, Sahiro Mizuno, Kazushige Goto
PURPOSE: To determine the effects of exercise-induced muscle damage, we examined irisin responses during level running (LR), with less muscle damage, and downhill running (DHR), with greater muscle damage under equivalent exercise duration and oxygen consumption (⩒O2) conditions. METHODS: Fifteen healthy men (age: 21.6 ± 2.0 y, height: 170 ± 1.3 cm, weight: 64.8 ± 2.7 kg) were randomly assigned to either the LR group (n = 8) or the DHR group (n = 7). Subjects in the LR group performed treadmill running at 70% of maximum oxygen uptake (⩒O2max) for 30 min on a 0% gradient...
June 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/30149420/role-of-dihydrotestosterone-in-whole-body-energy-utilization-during-acute-running-exercise-in-mice
#15
Nahyun Kim, Jisu Kim, Kiwon Lim, Jonghoon Park
PURPOSE: Dihydrotestosterone (DHT) plays an important role in various processes that utilize energy, including fat and carbohydrate oxidation. The purpose of this study was to determine the effect of inhibiting DHT formation during mid-intensity running exercise on energy expenditure and fat and carbohydrate oxidation in the whole body using a calorimetric chamber. METHODS: Twelve ICR adult male mice, 9 weeks of age, were randomized into two groups: CON (n = 6, no treatment with exercise) and CONIN (n = 6, DHT inhibitor treatment with exercise, SRD5A1A2 is an enzyme involved in the metabolism of free testosterone into DHT)...
June 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/30149419/regular-exercise-and-creatine-supplementation-prevent-chronic-mild-stress-induced-decrease-in-hippocampal-neurogenesis-via-wnt-gsk3%C3%AE-%C3%AE-catenin-pathway
#16
Yea-Hyun Leem, Morimasa Kato, Hyukki Chang
PURPOSE: Chronic stress can lead to mood-related psychomotor behaviors such as despair. Decreased hippocampal neurogenesis has been observed in patients with depression and in animal models of depression. Exercise enhances the population of the new born cells in the dentate gyrus (DG). A few studies have demonstrated that creatine has antidepressant effects in humans. However, the mechanism underpinning these effects is poorly understood. Therefore, we examined whether regular exercise and/or creatine was closely associated with the activity of the Wnt/GSK3β/β-catenin pathway in the hippocampal DG...
June 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/29673246/validity-of-the-6-minute-walk-test-and-step-test-for-evaluation-of-cardio-respiratory-fitness-in-patients-with-type-2-diabetes-mellitus
#17
Min Chul Lee
PURPOSE: The purpose of this study was to evaluate the reliability, reproducibility, and validity of the 6-minute walk test and step test as substitutes for ergometer exercise in patients with type 2 diabetes mellitus. METHODS: The study included 54 women aged 50-70 years who had type 2 diabetes mellitus. All the patients performed a cycle ergometer-graded exercise test for cardiorespiratory fitness (V̇O2max), followed by 6-minute walk and step tests. RESULTS: The mean distance covered during the 6-minute walk test was 538 ± 54 m, and the mean recovery heart rate after the step test was 93 ± 11 beats/min...
March 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/29673245/the-association-of-locomotive-and-non-locomotive-physical-activity-measured-by-an-accelerometer-with-functional-fitness-in-healthy-elderly-men-a-pilot-study
#18
Hyejoon Park, Wonil Park, Moran Lee, Nayoung Ko, Eunkyung Kim, Kazuko Ishikawa-Takata, Jonghoon Park
PURPOSE: The purpose of this study was to investigate the relationship of various aspects of daily physical activity, such as the number of steps, time spent in moderate to vigorous intensity physical activity (MVPA), and locomotive and non-locomotive MVPA measured by a triaxial accelerometer, with the functional fitness in healthy elderly men. METHODS: The subjects of this study were 22 healthy elderly men aged over 65 years. The participants wore a triaxial accelerometer for two weeks to estimate their daily physical activities...
March 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/29673244/changes-in-body-composition-blood-lipid-profile-and-growth-factor-hormone-in-a-patient-with-prader-willi-syndrome-during-24-weeks-of-complex-exercise-a-single-case-study
#19
Hee Joung Joung, In Soo Lim
PURPOSE: Prader-Willi syndrome (PWS) is a genetic disorder characterized by excessive appetite with progressive obesity and growth hormone (GH) deficiency. Excessive eating causes progressive obesity with increased risk of morbidities and mortality. Although GH treatment has beneficial effects on patients with PWS, adverse events have occurred during GH treatment. Exercise potentially has a positive effect on obesity management. The purpose of this research was to examine the effects of 24-week complex exercise program on changes in body composition, blood lipid profiles, and growth factor hormone levels in a patient with PWS...
March 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/29673243/the-effect-of-additional-carbohydrate-supplements-for-7-days-after-prolonged-interval-exercise-on-exercise-performance-and-energy-metabolism-during-submaximal-exercise-in-team-sports-athletes
#20
Hun-Young Park, Jisu Kim, Miyoung Park, Nana Chung, Kiwon Lim
PURPOSE: The purpose of our study was to determine the effectiveness of carbohydrate loading by additional carbohydrate supplements for 7 days after prolonged interval exercise on exercise performance and energy metabolism during submaximal exercise in team-sports athletes. METHODS: Twenty male team-sports athletes (14 soccer and 6 rugby players) volunteered to participate in the study and were equally divided into the experimental group (EXP, n=10) performing additional carbohydrate supplementation for 7 days after prolonged interval exercise until blood glucose level reaches 50 mg/dL or less and the control group (CON, n=10)...
March 30, 2018: Journal of Exercise Nutrition & Biochemistry
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