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Journal of Exercise Nutrition & Biochemistry

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https://www.readbyqxmd.com/read/30149426/age-and-sex-related-differences-in-myosin-heavy-chain-isoforms-and-muscle-strength-function-and-quality-a-cross-sectional-study
#1
Seung-Lyul Oh, Sang Hoon Yoon, Jae-Young Lim
PURPOSE: Declining muscle strength and function are hallmarks of the aging process. This study aimed to determine sex-related differences in myosin heavy chain (MHC) isoforms and muscle mass, strength, and quality with aging. METHODS: This cross-sectional study recruited 53 healthy participants (32 men, 21 women) aged 20-85 years who were divided into four groups: young men (n=17, YM, 29.23±4.51), older men (n=15, OM, 71.87±3.42), young women (n=11, YW, 29.64±4...
June 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/30149425/role-of-l-carnitine-and-oleate-in-myogenic-differentiation-implications-for-myofiber-regeneration
#2
Hojun Lee, Jae-Young Lim, Seung-Jun Choi
PURPOSE: Myogenic progenitors play a critical role in injury-induced myofiber regeneration. The purpose of this study was to characterize the effects of oleate and L-carnitine on the overall behavior of proliferating myogenic progenitors (myoblasts) and its link to the mitochondrial biogenic process. METHODS: C2C12 myoblasts were cultured either with no treatment, oleate, L-carnitine, or their mixture. Proliferating myoblasts were investigated under a phase-contrast microscope...
June 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/30149424/smallanthus-sonchifolius-leaf-attenuates-neuroinflammation
#3
Suji Baek, Nan Hee Choi, Kang-Pa Lee, Hyunjhung Jhun, Jisu Kim
PURPOSE: Yacon, Smallanthus sonchifolius, has anti-hypertensive, anti-inflammatory, and anti-cancer potential. However, its neuroprotective and anti-neuroinflammatory effects are unknown. Moreover, activation of microglia has been considered a mechanism in the development of Alzheimer's disease. Therefore, the aim of this study was to determine the neuroprotective effects of an ethanolic yacon leaf extract (YLE) on lipopolysaccharide (LPS)-induced neuroinflammation in vitro and in vivo...
June 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/30149423/non-exercise-activity-thermogenesis-neat-a-component-of-total-daily-energy-expenditure
#4
Nana Chung, Mi-Young Park, Jisu Kim, Hun-Young Park, Hyejung Hwang, Chi-Ho Lee, Jin-Soo Han, Jaemoo So, Jonghoon Park, Kiwon Lim
PURPOSE: The purpose of this review is to promote awareness of non-exercise activity thermogenesis (NEAT) as a new strategy to increase energy expenditure, and to manage obesity. METHODS: The content of this review is based on a literature search of PubMed and the Google Scholar search engine, using the search terms obesity, energy expenditure, non-exercise activity thermogenesis (NEAT), and sitting disease. RESULTS: Daily energy expenditure is of great interest because most obese individuals have no exercise activity-related thermogenesis (EAT); thus their physical activity-related energy expenditure (PEE) is comprised almost entirely of NEAT...
June 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/30149422/the-effects-of-the-elastin-polymorphisms-on-carotid-intima-media-thickness-in-women-aged-30-70
#5
Seung-Taek Lim, Jin-Kee Park, Sang-Hyuk Park, Eun-Jae Lee, Woo-Nam Kim, Seok-Ki Min
PURPOSE: Elastin is one of the major determinants of arterial distensibility of large blood vessels that forms the principal component of elastic fibers from the media of arteries. However, the association between elastin(ELN) genotype and vascular function is still unclear. METHODS: 120women were recruited from the Saha-gu (Busan, Korea) Community Center. Measurements of body composition and vascular function included carotid intima-media thickness (CIMT), carotid artery luminal diameter (CLD), minimum (diastolic) artery luminal diameter (CLDmin) and maximum (systolic) artery luminal diameter (CLDmax)...
June 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/30149421/irisin-response-to-downhill-running-exercise-in-humans
#6
Yoshifumi Tsuchiya, Sahiro Mizuno, Kazushige Goto
PURPOSE: To determine the effects of exercise-induced muscle damage, we examined irisin responses during level running (LR), with less muscle damage, and downhill running (DHR), with greater muscle damage under equivalent exercise duration and oxygen consumption (⩒O2) conditions. METHODS: Fifteen healthy men (age: 21.6 ± 2.0 y, height: 170 ± 1.3 cm, weight: 64.8 ± 2.7 kg) were randomly assigned to either the LR group (n = 8) or the DHR group (n = 7). Subjects in the LR group performed treadmill running at 70% of maximum oxygen uptake (⩒O2max) for 30 min on a 0% gradient...
June 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/30149420/role-of-dihydrotestosterone-in-whole-body-energy-utilization-during-acute-running-exercise-in-mice
#7
Nahyun Kim, Jisu Kim, Kiwon Lim, Jonghoon Park
PURPOSE: Dihydrotestosterone (DHT) plays an important role in various processes that utilize energy, including fat and carbohydrate oxidation. The purpose of this study was to determine the effect of inhibiting DHT formation during mid-intensity running exercise on energy expenditure and fat and carbohydrate oxidation in the whole body using a calorimetric chamber. METHODS: Twelve ICR adult male mice, 9 weeks of age, were randomized into two groups: CON (n = 6, no treatment with exercise) and CONIN (n = 6, DHT inhibitor treatment with exercise, SRD5A1A2 is an enzyme involved in the metabolism of free testosterone into DHT)...
June 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/30149419/regular-exercise-and-creatine-supplementation-prevent-chronic-mild-stress-induced-decrease-in-hippocampal-neurogenesis-via-wnt-gsk3%C3%AE-%C3%AE-catenin-pathway
#8
Yea-Hyun Leem, Morimasa Kato, Hyukki Chang
PURPOSE: Chronic stress can lead to mood-related psychomotor behaviors such as despair. Decreased hippocampal neurogenesis has been observed in patients with depression and in animal models of depression. Exercise enhances the population of the new born cells in the dentate gyrus (DG). A few studies have demonstrated that creatine has antidepressant effects in humans. However, the mechanism underpinning these effects is poorly understood. Therefore, we examined whether regular exercise and/or creatine was closely associated with the activity of the Wnt/GSK3β/β-catenin pathway in the hippocampal DG...
June 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/29673246/validity-of-the-6-minute-walk-test-and-step-test-for-evaluation-of-cardio-respiratory-fitness-in-patients-with-type-2-diabetes-mellitus
#9
Min Chul Lee
PURPOSE: The purpose of this study was to evaluate the reliability, reproducibility, and validity of the 6-minute walk test and step test as substitutes for ergometer exercise in patients with type 2 diabetes mellitus. METHODS: The study included 54 women aged 50-70 years who had type 2 diabetes mellitus. All the patients performed a cycle ergometer-graded exercise test for cardiorespiratory fitness (V̇O2max), followed by 6-minute walk and step tests. RESULTS: The mean distance covered during the 6-minute walk test was 538 ± 54 m, and the mean recovery heart rate after the step test was 93 ± 11 beats/min...
March 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/29673245/the-association-of-locomotive-and-non-locomotive-physical-activity-measured-by-an-accelerometer-with-functional-fitness-in-healthy-elderly-men-a-pilot-study
#10
Hyejoon Park, Wonil Park, Moran Lee, Nayoung Ko, Eunkyung Kim, Kazuko Ishikawa-Takata, Jonghoon Park
PURPOSE: The purpose of this study was to investigate the relationship of various aspects of daily physical activity, such as the number of steps, time spent in moderate to vigorous intensity physical activity (MVPA), and locomotive and non-locomotive MVPA measured by a triaxial accelerometer, with the functional fitness in healthy elderly men. METHODS: The subjects of this study were 22 healthy elderly men aged over 65 years. The participants wore a triaxial accelerometer for two weeks to estimate their daily physical activities...
March 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/29673244/changes-in-body-composition-blood-lipid-profile-and-growth-factor-hormone-in-a-patient-with-prader-willi-syndrome-during-24-weeks-of-complex-exercise-a-single-case-study
#11
Hee Joung Joung, In Soo Lim
PURPOSE: Prader-Willi syndrome (PWS) is a genetic disorder characterized by excessive appetite with progressive obesity and growth hormone (GH) deficiency. Excessive eating causes progressive obesity with increased risk of morbidities and mortality. Although GH treatment has beneficial effects on patients with PWS, adverse events have occurred during GH treatment. Exercise potentially has a positive effect on obesity management. The purpose of this research was to examine the effects of 24-week complex exercise program on changes in body composition, blood lipid profiles, and growth factor hormone levels in a patient with PWS...
March 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/29673243/the-effect-of-additional-carbohydrate-supplements-for-7-days-after-prolonged-interval-exercise-on-exercise-performance-and-energy-metabolism-during-submaximal-exercise-in-team-sports-athletes
#12
Hun-Young Park, Jisu Kim, Miyoung Park, Nana Chung, Kiwon Lim
PURPOSE: The purpose of our study was to determine the effectiveness of carbohydrate loading by additional carbohydrate supplements for 7 days after prolonged interval exercise on exercise performance and energy metabolism during submaximal exercise in team-sports athletes. METHODS: Twenty male team-sports athletes (14 soccer and 6 rugby players) volunteered to participate in the study and were equally divided into the experimental group (EXP, n=10) performing additional carbohydrate supplementation for 7 days after prolonged interval exercise until blood glucose level reaches 50 mg/dL or less and the control group (CON, n=10)...
March 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/29673242/study-of-muscle-contraction-induced-by-electrical-pulse-stimulation-and-nitric-oxide-in-c2c12-myotube-cells
#13
In Ho Lee, Yoon Jeong Lee, Hyobin Seo, Yi Seul Kim, Ju-Ock Nam, Byung-Duk Jeon, Tae-Dong Kwon
PURPOSE: This study aimed to examine the independent effect of electrical pulse stimulation(EPS) and nitric oxide(NO) on muscle contraction and their synergistic or combined effect on contraction phenomenon using C2C12 mouse skeletal muscle cells. METHODS: Some differentiated C2C12 myotube cells were untreated (control). Other cells did not receive EPS and did receive 0.5, 1.0, or 2.0 mM of the NO donor, S-nitroso-N-acetyl-penicillamine (SNAP; -E/S0.5, -E/S1.0, and -E/S2...
March 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/29673241/effect-of-acute-mid-intensity-treadmill-exercise-on-the-androgen-hormone-level-and-uncoupling-protein-1-expression-in-brown-fat-tissue-of-mouse
#14
Nahyun Kim, Jisu Kim, Choongsung Yoo, Kiwon Lim, Takayuki Akimoto, Jonghoon Park
PURPOSE: Brown adipose tissue (BAT) plays an important role in metabolizing different substances, including androgens. The aim of this study was to determine whether a single bout of aerobic exercise would increase the androgen hormone concentration in mouse BAT and whether its increase was associated with uncoupling protein-1 (UCP-1), protein kinase A (PKA)-related mechanism in BAT. METHODS: Twenty, 9-week-old ICR adult male micewere randomly divided into three groups: Control (n=6, CON), Exercise (n=7, EX), and Exercise + SRD5A1A2 inhibitor (n=7, EXIN)...
March 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/29673239/effects-of-treadmill-exercise-on-pi3k-akt-gsk-3%C3%AE-pathway-and-tau-protein-in-high-fat-diet-fed-rats
#15
Jae-Hoon Jeong, Eun-Bum Kang
PURPOSE: This study aimed to clearly evaluate the effects of obesity on cerebral health. Thus, we induced obesity in rats using a long-term high-fat diet (HFD), then investigated its effects on insulin signaling and tau hyperphosphorylation. Additionally, we examined the effects of 8 weeks of treadmill exercise (TE) on insulin signaling and tau hyperphosphorylation. METHODS: Rats were separated into Normal Diet-Control, HFD-Control, and HFD-TE groups. TE loads were gradually increased...
March 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/29673238/association-of-exercise-induced-autophagy-upregulation-and-apoptosis-suppression-with-neuroprotection-against-pharmacologically-induced-parkinson-s-disease
#16
Yong Chul Jang, Dong Joo Hwang, Jung Hoon Koo, Hyun Seob Um, Nam Hee Lee, Dong Cheol Yeom, Youngil Lee, Joon Yong Cho
PURPOSE: We investigated whether treadmill exercise (TE)-induced neuroprotection was associated with enhanced autophagy and reduced apoptosis in a mouse model of pharmacologically induced Parkinson's disease (PD). METHODS: PD was induced via the administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). C57BL/6 male mice were randomly assigned to the following three groups: control (C57BL, n=10), MPTP with probenecid (MPTP/C, n=10), and MPTP/ C plus exercise (MPTP-TE, n=10)...
March 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/29370674/effects-of-acute-voluntary-loaded-wheel-running-on-bdnf-expression-in-the-rat-hippocampus
#17
Minchul Lee, Hideaki Soya
PURPOSE: Voluntary loaded wheel running involves the use of a load during a voluntary running activity. A muscle-strength or power-type activity performed at a relatively high intensity and a short duration may cause fewer apparent metabolic adaptations but may still elicit muscle fiber hypertrophy. This study aimed to determine the effects of acute voluntary wheel running with an additional load on brain-derived neurotrophic factor (BDNF) expression in the rat hippocampus. METHODS: Ten-week old male Wistar rats were assigned randomly to a (1) sedentary (Control) group; (2) voluntary exercise with no load (No-load) group; or (3) voluntary exercise with an additional load (Load) group for 1-week (acute period)...
December 31, 2017: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/29370673/arc-arg3-1-protein-expression-in-dorsal-hippocampal-ca1-a-candidate-event-as-a-biomarker-for-the-effects-of-exercise-on-chronic-stress-evoked-behavioral-abnormalities
#18
Yea-Hyun Leem, Hyukki Chang
PURPOSE: Chronic stress is a risk factor for behavioral deficits, including impaired memory processing and depression. Exercise is well known to have beneficial impacts on brain health. METHODS: Mice were forced to treadmill running (4-week) during chronic restraint stress (6h/21d), and then behavioral tests were conducted by Novel object recognition, forced swimming test: FST, sociality test: SI. Dissected brain was stained with anti-calbindin-d28k and anti-Arc antibodies...
December 31, 2017: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/29370672/weight-reduction-does-not-induce-an-undesirable-decrease-in-muscle-mass-muscle-strength-or-physical-performance-in-men-with-obesity-a-pilot-study
#19
Bokun Kim, Takehiko Tsujimoto, Rina So, Xiaoguang Zhao, Sechang Oh, Kiyoji Tanaka
PURPOSE: To date, there have been no reports on whether weight reduction causes decreases in muscle mass, muscle strength, or physical performance that could lead to health problems. Thus, in this pilot study, we investigated the appropriateness of the changes in muscle mass, muscle strength and physical performance after weight reduction. METHODS: Obese men who completed a weight reduction program to decrease and maintain a body mass index (BMI) of less than 25 kg/m2 for one year were recruited for the study...
December 31, 2017: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/29370671/the-synergistic-effect-of-protein-complex-supplementation-combined-with-12-weeks-of-resistance-training-on-isokinetic-muscular-function-in-untrained-young-males
#20
Jiwoong Jang, Hun-Young Park, Choongsung Yoo, Yeram Park, Jisu Kim, Kiwon Lim
PURPOSE: Resistance exercise training (RET) and an additional intake of dietary protein supplements may improve muscle mass and muscular function, and reduce inflammatory markers. The types, amount, and timing of dietary protein supplements are important for the synergistic effects of resistance training and dietary protein supplements. We hypothesized that a 25.1 g protein complex supplement taken for 12 weeks, immediately before and after resistance exercise, would enhance fat free mass and isokinetic muscular function in young untrained males...
December 31, 2017: Journal of Exercise Nutrition & Biochemistry
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