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Turkish Journal of Medical Sciences

Cem Peşkersoy, Şule Peker, Ayşegül Kaya, Aycan Ünalp, Necmi Gökay
BACKGROUND/AIM: Although migraine is a common disorder, there is a lack of research investigating the possible relationship between migraine and oral health. The aim of the present study was to explore the relationship between temporomandibular disorders, bruxism, dental caries, periodontal status, and migraine disorder in a multicenter, parallel, case-controlled clinical study. MATERIALS AND METHODS: A total of 2001 participants were divided into two groups: migraineurs (nm = 998) and nonmigraineurs (nh = 1003)...
April 19, 2016: Turkish Journal of Medical Sciences
Mehtap Şahin, Fikriye Figen Ayhan, Pınar Borman, Hüseyin Atasoy
BACKGROUND/AIM: The role of hip muscles in the rehabilitation of patellofemoral pain syndrome has recently received interest. The aim of this study was to compare the efficiencies of hip exercises alongside knee exercises versus only knee exercises on pain, function, and isokinetic muscle strength in patients with this syndrome. MATERIALS AND METHODS: Fifty-five young female patients (mean age: 34.1 ± 6.2 years; mean BMI: 25.9 ± 3.9 kg/m2) with patellofemoral pain syndrome were included...
February 17, 2016: Turkish Journal of Medical Sciences
Yusuf Aydin, Elif Önder
No abstract text is available yet for this article.
2016: Turkish Journal of Medical Sciences
Ayşe Nurdan Korkmaz, Billur Çalişkan, Fatma Erdem
No abstract text is available yet for this article.
2016: Turkish Journal of Medical Sciences
Murat İlhan Atagün, Şükrü Alperen Korkmaz, Çağlar Soykan, Derya Büyüköz, Serdar Süleyman Can, Ali Çayköylü
No abstract text is available yet for this article.
2016: Turkish Journal of Medical Sciences
Sumera Sajjad, Sadia Tobassum, Umer Farooq, Husna Malik, Musadiq İdris
BACKGROUND/AIM: To assess the therapeutic effects of naloxone and yohimbine on polycystic ovary syndrome (PCOS) in a rabbit model in terms of body weight and endocrinological parameters (luteinizing hormone, insulin, and estradiol). MATERIALS AND METHODS: A total of 50 adult, reproductively mature female rabbits (Oryctolagus cuniculus) were divided into five groups (n = 10/group). In the control group PCOS was not induced (negative control group), whereas in the remaining four groups (n = 40) PCOS was induced with a single i...
2016: Turkish Journal of Medical Sciences
Asma Mahfoudh Boussaid, Rabi Selmi, Mohamed Bejaoui, Kaouther Hadj Ayed, Mohamed Amine Zaouali, Hassen Ben Abdennebi
BACKGROUND/AIM: The aim of this study was to compare the effects of single and repeated trimetazidine (TMZ) administration against warm hepatic ischemia/reperfusion (I/R) injury and to explore the possible mechanisms affected by TMZ. MATERIALS AND METHODS: Wistar rats were divided into 4 groups (n = 6). Sham: rats were subjected to dissection. I/R: rats were subjected to 60 min of partial hepatic ischemia followed by 24 h of reperfusion. TMZ1: Same as I/R group but rats were pretreated with a single dose of TMZ (10 mg/kg, intraperitoneal injection) 30 min before warm ischemia...
2016: Turkish Journal of Medical Sciences
Emre Mutlu, Selçuk İlhan, Elif Onat, Murat Kara, Engin Şahna
BACKGROUND/AIM: The effects of AT2 receptor agonist novokinin on blood pressure, eNOS, NADPH oxidase, protein arginine methyltransferases (PRMTs), and Rho kinase in hypertension were investigated. Furthermore, in isolated thoracic aorta rings, contractile and dilator responses were studied. MATERIALS AND METHODS: To develop hypertension, L-NAME was administered intraperitoneally and salt was given with tap water (1%) for 4 weeks. Novokinin was administered intraperitoneally for the last 2 weeks...
2016: Turkish Journal of Medical Sciences
Florin Muselin, Romeo Teodor Cristina, Violeta İgna, Eugenia Dumitrescu, Diana Brezovan, Alexandra Trif
BACKGROUND/AIM: The effects of aluminium exposure on reproductive biomarkers in male rats were followed in a three-generation study. MATERIALS AND METHODS: Forty Wistar male rats (F0) were divided into the following groups: control (C), receiving only tap water, and three experimental (E) groups, receiving aluminium sulphate (AS) (E1: 200 ppb, E2: 400 ppb, and E3: 1000 ppb) in drinking water for a 6-month exposure period. To obtain F1, three males from each group were mated with previously unexposed females (1:2 sex ratios) that during gestation and lactation were exposed to the same AS levels as males...
2016: Turkish Journal of Medical Sciences
Rafet Özay, Osman Yüksel Yavuz, Abit Aktaş, Funda Yiğit, Nuri Eralp Çetinalp, Hacı Mustafa Özdemir, Zeki Şekerci
BACKGROUND/AIM: The study was designed to investigate whether local administration of a mixture composed of cepae extract, allantoin, and heparin (CAH) decreased already formed epidural fibrosis (EF) at the laminectomy site. MATERIALS AND METHODS: Twenty-four adult male Sprague Dawley rats were equally divided into four groups. Laminectomy was performed at the L5 level in all rats. The group 2 and group 4 rats were treated with local drug administration. While the group 1 and 2 rats were sacrificed after 6 weeks, the remaining rats were reoperated and CAH mixture was applied in group 4...
2016: Turkish Journal of Medical Sciences
Soheil Safarian, Yadollah Azarmi, Ali Jahanban-Esfahlan, Hasan Jahanban-Esfahlan
BACKGROUND/AIM: Almond hull is produced in high amounts and mostly used as livestock feed. This study was designed to examine the impact of almond hull powder (AHP) administration on lipid profile and antioxidant activities in plasma and liver in hyperlipidemic rats. MATERIALS AND METHODS: As the first step, the antioxidant capacity and radical scavenging activity of AHP were determined using calorimetric methods. Then 36 adult male Wistar rats were randomly divided into 6 groups: group 1 with oral administration of 10% AHP, group 2 with oral administration of 20% AHP, group 3 with oral administration of 30% AHP, group 4 as a positive control with a high cholesterol diet, group 5 as a negative control with a normal diet, and group 6 as a sham group with a normal diet and 20% AHP...
2016: Turkish Journal of Medical Sciences
Elif Sari, Bülent Bakar, Bahram Sarkarati, Önder Bozdoğan, Tarık Çavuşoğlu
BACKGROUND/AIM: The survival of autologous fat graft tissue is dependent on various factors such as vascularization and inflammation. The aim of the present study was to evaluate the possible beneficial effects of low-dose methotrexate (LD-MTX) on fat graft volume and survival. MATERIALS AND METHODS: A total of 13 male Wistar albino rats were divided into two groups, a control group and an LD-MTX group. An autologous fat graft obtained from the inguinal region of each rat was transferred to its back...
2016: Turkish Journal of Medical Sciences
Çiğdem Selli, Yasemin Eraç, Metiner Tosun
BACKGROUND/AIM: This study investigates whether 1-(2-trifluoromethylphenyl)-imidazole (TRIM), originally proposed as a nitric oxide synthase inhibitor and also suggested to be an inhibitor of store-operated calcium entry in mouse anococcygeal muscle, inhibits receptor-independent and -dependent responses in rat thoracic aorta. MATERIALS AND METHODS: Cyclopiazonic acid- and serotonin-induced vascular responses were investigated in aortic segments isolated from male Sprague Dawley rats using isolated tissue experiments...
2016: Turkish Journal of Medical Sciences
Özge Kolkesen Şahin, Müge Çina Aksoy, Mustafa Cihat Avunduk
BACKGROUND/AIM: The aim of the present study is to investigate the effects of cigarette smoke (CS) and simultaneous application of resveratrol on bone healing histomorphometrically and to evaluate the effects of resveratrol on negative effects of CS. MATERIALS AND METHODS: For 4 weeks, Sprague Dawley rats were exposed to cigarette smoke at the equivalent of 6 cigarettes per day. After this period, monocortical defects were created in femurs by a trephine bur on day 28...
2016: Turkish Journal of Medical Sciences
Hüseyin Çelik, Tahsin Turunç, Nebil Bal, Eray Hasirci, Alaaddin Akay, Çetin Levent Peşkircioğlu
BACKGROUND/AIM: We aimed to evaluate the importance of maspin expression in testicular tumors with germ cells, its effect on prognosis, and the relation with angiogenesis factors. MATERIALS AND METHODS: The paraffin blocks of the orchiectomy materials of 32 patients who had undergone orchiectomy due to testicular tumors were taken within the scope of the study. The specimens of the cases included in the study group were reexamined under light microscope. RESULTS: While just one maspin-positive sample was found in the seminoma cases, maspin stained positively in 6 of the nonseminoma germ cell tumors (NSGCTs)...
2016: Turkish Journal of Medical Sciences
Roya Vahedi Shahandashti, Rouha Kasra Kermanshahi, Parinaz Ghadam
BACKGROUND/AIM: The spread of antibiotic-resistant pathogens has resulted in the need for new treatments. The aim of the present study is to investigate the effect of bacteriocin from Lactobacillus acidophilus ATCC 4356 and Lactobacillus plantarum ATCC 8014 on planktonic and biofilm forms of Serratia marcescens strains. MATERIALS AND METHODS: The direct antagonism of the L. plantarum and L. acidophilus cell-free supernatant on S. marcescens cultures was determined using an optical density assay...
2016: Turkish Journal of Medical Sciences
Servet Güreşci, Özlem Özmen, Metin Uzman, Gülçin Şimşek, Ebru Tatci, Atila Gökçek, Abdullah Özgür Yeniova
BACKGROUND/AIM: To investigate whether focal high maximum standardized uptake value (SUVmax) determined by 18-fluorodeoxyglucose (FDG) positron emission tomography (PET)-computed tomography (CT) imaging is correlated with proliferation index in the colorectal region. MATERIALS AND METHODS: SUVmax values of 31 colorectal neoplasms that were incidentally detected during PET-CT examination were compared to dysplasia degree, histopathologic diagnosis, and immunohistochemical expression of the Ki-67 proliferation marker...
2016: Turkish Journal of Medical Sciences
Volkan Zeybek, Yücel Arisoy
BACKGROUND/AIM: Peripheral blood DNA profiles are often used in forensic identification and paternity investigations. Currently, because of the increasing number of patients who undergo transplantation, determining the history of transplantation has gained importance in forensic cases. The aim of this study was to investigate the potential of genetic chimerism analysis of blood, hair follicle, and buccal swab samples for the forensic identification of transplant patients. MATERIALS AND METHODS: Blood, hair follicle, and buccal swab samples from five patients who had undergone allogeneic peripheral blood stem cell transplantation (allo-PBSCT) and 35 patients who had undergone liver transplantation were analyzed...
2016: Turkish Journal of Medical Sciences
Olivera Mitrović Ajtić, Slobodan Todorović, Miloš Diklić, Tijana Subotički, Bojana Beleslin-Čokić, Gordana Jovčić, Vladan Čokić
BACKGROUND/AIM: The purpose of this study was to investigate proliferation and differentiation markers in colorectal adenocarcinoma and their correlation with clinicopathological factors. MATERIALS AND METHODS: Samples were collected from 38 patients with colorectal adenocarcinoma and 10 healthy controls. E-cadherin, carcinoembryonic antigen (mCEA), cyclin B1, vascular endothelial growth factor (VEGF), and erythropoietin (EPO) receptor (EPOR) were examined by immunohistochemistry; VEGF and EPO were examined by real-time PCR...
2016: Turkish Journal of Medical Sciences
Barış Akça, Köksal Dönmez, Olcay Murat Dişli, Feray Akgül Erdil, Mehmet Cengiz Çolak, İlhan Koray Aydemir, Bektaş Battaloğlu, Nevzat Erdil
BACKGROUND/AIM: To investigate the effects of pulmonary hypertension on early clinical variables in patients undergoing coronary artery bypass grafting surgery. MATERIALS AND METHODS: The preoperative echocardiographic data of patients who underwent isolated coronary artery bypass surgery were evaluated retrospectively. A total of 1244 patients were included in the study. The patients were divided into two groups: one group consisted of patients with systolic pulmonary artery pressure (SPAP) values equal to or greater than 30 mmHg (Group 1, n = 184), while the other group consisted of patients with SPAP values below 30 mmHg (Group 2, n = 1060)...
2016: Turkish Journal of Medical Sciences
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