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Analytical and Quantitative Cytopathology and Histopathology

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https://www.readbyqxmd.com/read/27386636/gentian-violet-used-as-an-epithelial-cell-monolayer-stain-in-the-scratch-wound-healing-assay
#1
LETTER
César Rivera
No abstract text is available yet for this article.
April 2016: Analytical and Quantitative Cytopathology and Histopathology
https://www.readbyqxmd.com/read/27386635/malignant-bilateral-basifrontal-solitary-fibrous-tumor-a-case-report
#2
Nidhi Mahajan, Kavite Gaur, Shramana Mandal, Ravindra Kumar Saran, Hukum Singh
BACKGROUND: Solitary fibrous tumors are rare benign mesenchymal neoplasms characterized by involvement of many sites all over the body with uncommon presentation within the cranium. Furthermore, malignant bilateral basifrontal solitary fibrous tumor is extremely rare. Although uncommon, this rare entity may be included in the differential diagnosis of frontal tumors in adults, to ensure complete surgical resection. The tumor falls under the spectrum of fibroblastic proliferation and shares close morphological overlap with meningiomas and hemangiopericytomas, posing a diagnostic challenge for the histopathologist...
April 2016: Analytical and Quantitative Cytopathology and Histopathology
https://www.readbyqxmd.com/read/27386634/influence-of-radiation-exposure-during-radiotherapy-evidence-for-the-increase-of-versican-and-heparin-binding-egf-like-growth-factor-concentrations
#3
Mahmut Kemal Ozbilgin, Caner Aktas, Elgin Turkoz Uluer, Mustafa Cagatay Buyukuysal, Manuchehr Salehi Gareveran, Cengiz Kurtman
OBJECTIVE: To investigate the reaction of versican and heparin-binding EGF-like growth factor (HB-EGF) molecule concentrations to acute radiation exposure in normal bladder and rectal tissue samples in order to gain more insight into the effects of cancer radiotherapy. STUDY DESIGN: Four groups with 6 male adult Swiss Albino mice per group were investigated. The mice bladder and rectum tissue samples were subjected to a 10-Gy single-dose radiation exposure in the pelvic region with a Co-60 teletherapy device and investigated 1, 2, and 7 days after radiation exposure, with 1 reference group which was not exposed to radiation...
April 2016: Analytical and Quantitative Cytopathology and Histopathology
https://www.readbyqxmd.com/read/27386633/effect-of-zoledronic-acid-application-on-different-graft-materials-in-calvarial-bone-defect-models-an-experimental-analysis
#4
Mahmut Koparal, Belgin Gülsün, Engin Deveci, K Serkan Agacayak, Arif Hamidi
OBJECTIVE: To determine the effect of zoledronic acid on graft materials in bone calvarial defects. STUDY DESIGN: Eighty adult (12 weeks) Sprague-Dawley male rats weighing from 300-350 g were divided into groups: calvarial defect, calvarial defect + synthetic graft, and calvarial defect + xenograft. All groups received zoledronate intravenously for a week after surgery and were sacrificed at either 6 or 12 weeks after their operation. The rat calvariae were fixed in 10% neutral buffered formalin before decalcification in 10% ethylenediaminetetraacetic acid for 20 days...
April 2016: Analytical and Quantitative Cytopathology and Histopathology
https://www.readbyqxmd.com/read/27386632/effects-of-potentilla-fulgens-as-a-prophylactic-agent-in-tibial-defects-in-rats
#5
Mahmut Koparal, Sevgi Ïrtegün, Hilal Alan, Engin Deveci, Belgin Gülsün, Ugur Seker
OBJECTIVE: To investigate the effects of Potentilla fulgens as a prophylactic agent on tibial defects in the rat. STUDY DESIGN: Twenty-eight male Wistar albino rats weighing 200-215 g each were divided into 3 experimental groups. The tibial bone defect group served as the control group. The experimental groups were Potentilla fulgens with tibial defect (14 days) and Potentilla fulgens with tibial defect (28 days). Extract of Potentilla fulgens was mixed with water (400 mg/kg/day) and given to groups 14 and 28 as drinking water...
April 2016: Analytical and Quantitative Cytopathology and Histopathology
https://www.readbyqxmd.com/read/27386631/effects-of-cyclooxygenase-on-the-urothelium-of-the-urinary-bladder-of-mice-exposed-to-pelvic-radiation
#6
M Kemal Ozbilgin, Tuna Onal, Cemil Ozcan, Merve Temel, Caner Aktas, Manuchehr Salehi Gareveran, Elgin Turkoz Uluer, Sevinc Inan, Cengiz Kurtman
OBJECTIVE: To determine the role of cyclooxygenase (COX) expression in the urothelium of the urinary bladder during radiation injury caused by pelvic radiotherapy for cancer therapy. STUDY DESIGN: Twenty-four male Swiss Albino mice were separated into 4 groups. The first group was the control group (Group 1) and the second, third, and fourth groups were euthanized after 24 hours (Group 2), 48 hours (Group 3), and 7 days (Group 4), respectively. A single-fractioned 10 Gy of ionizing radiation was applied to all mice's pelvic zone with Co-60...
April 2016: Analytical and Quantitative Cytopathology and Histopathology
https://www.readbyqxmd.com/read/27386630/effects-of-low-intensity-treadmill-exercise-on-sciatic-nerve-in-experimental-diabetic-neuropathy
#7
Ismail Gulsen, Murat Demiroglu, Abdurrahman Aycan, Rifki Ucler, Ilker Alaca, Zeynep Nur Orhon, Mehmet Kanter
OBJECTIVE: To investigate the potential beneficial effects of low-intensity exercise on histopathological changes of sciatic nerves in streptozotocin (STZ)-induced diabetic rats. STUDY DESIGN: The rats were allotted randomly into 3 experimental groups: A (control), B (diabetic untreated), and C (diabetic treated with low-intensity exercise); each group contained 8 animals. Groups B and C received STZ. Diabetes was induced in 2 groups by a single intraperitoneal injection of STZ (40 mg/kg, freshly dissolved in 0...
April 2016: Analytical and Quantitative Cytopathology and Histopathology
https://www.readbyqxmd.com/read/27386629/protective-effects-of-vitamin-e-on-methotrexate-induced-jejunal-mucosal-damage-in-rats
#8
Busra Burcu, Mehmet Kanter, Zeynep Nur Orhon, Oguzhan Yarali, Rukiye Karabacak
OBJECTIVE: To investigate the possible protective effects of Vitamin E (Vit E) on oxidative stress and jejunal damage in the rat intestinal mucosa after methotrexate (MTX)-induced enterotoxicity. STUDY DESIGN: Rats were divided into 3 groups: control, MTX, and MTX+ Vit E; each group contained 8 animals. The control group was given physiological serum in addition to sunflower oil for 3 days. The second group was given sunflower oil with intragastric tube daily, followed by MTX injection (20 mg/kg intraperitoneally)...
April 2016: Analytical and Quantitative Cytopathology and Histopathology
https://www.readbyqxmd.com/read/27386628/immunohistochemical-expression-and-clinical-significance-of-wnt11-and-bcl2a1-in-complete-moles
#9
Zhimin Hao, Weiguo Lü, Xiaodong Cheng, Caiyun Zhou
OBJECTIVE: To investigate Wnt11 and BCL2A1 immunohistochemical expression in complete moles and normal villi. STUDY DESIGN: The expression of Wnt11 and BCL2A1 in 84 complete moles and 30 normal first-trimester villi were detected by Envision immunohistochemistry. Quantitative evaluation according to color deconvolution and immunoreactive score was performed. Data was analyzed using Kruskal-Wallis test, Pearson test, and ROC curve. RESULTS: Of 84 complete moles, 14 developed to post-molar gestational trophoblastic neoplasia, and the others regressed spontaneously...
April 2016: Analytical and Quantitative Cytopathology and Histopathology
https://www.readbyqxmd.com/read/27386627/distribution-and-developmental-changes-of-neuropeptide-y-and-its-y1-receptor-like-immunoreactive-cells-in-the-duck-thymus
#10
Min Jiang, Chunyu Liu, Jing Fang, Xi Peng, Junde Fan, Hengmin Cui, Heng Yin
OBJECTIVE: To investigate the distribution and developmental changes of Neuropeptide-Y (NPY) and its Y1 receptor (NPYY1)-like immunoreactivity cells in the duck thymus using immunohistochemistry associated with morphological analysis. STUDY DESIGN: Studies were carried out on Tianfu ducks on days 14, 18, 22, and 26 of embryogenesis (E14, E18, E22, and E26) as well as at 0 (neonatal stage), 1, 3, 5, 8, 11, 14, 17, 20, 26, 29, and 32 weeks of postnatal development (P0, P1, P3, P5, P8, P11, P14, P17, P20, P26, P29, and P32)...
April 2016: Analytical and Quantitative Cytopathology and Histopathology
https://www.readbyqxmd.com/read/27386626/automated-region-based-prostate-cancer-cell-nuclei-localization-part-of-a-prognostic-modality-tool-for-prostate-cancer-patients
#11
Nilgoon Zarei, Amir Bakhtiari, Jagoda Korbelik, Anita Carraro, Mira Keyes, Martial Guillaud, Calum MacAulay
BACKGROUND: Prostate cancer is a disease of disrupted cell genomes. Quantification of DNA from cytology preparations can yield prognostic information about tissue biological behaviors; however, this process is very labor-intensive to perform. Quantitative digital pathology can measure the structural chromatin changes associated with neoplasia and can enable prognostic and predictive assays based on imaging of sectioned prostate tissue. OBJECTIVE: To design an automated system to recognize and localize cell nuclei in images of stained sectioned tissue (first step in enabling quantitative digital pathology)...
April 2016: Analytical and Quantitative Cytopathology and Histopathology
https://www.readbyqxmd.com/read/27363068/another-case-of-multifocal-blue-nevus-of-the-prostate
#12
LETTER
Rossella Ponte, Jean Louis Ravetti, Paola Calamaro, Mauro Pacella, Carlo Toncini
No abstract text is available yet for this article.
February 2016: Analytical and Quantitative Cytopathology and Histopathology
https://www.readbyqxmd.com/read/27363067/inverted-papilloma-of-the-bladder-coexisting-with-urothelial-carcinoma-a-case-report
#13
Ricardo Santana Veiga, João Cassis, Pedro Oliveira, António Lopez-Beltran
BACKGROUND: Inverted papilloma (IP) is an unusual benign neoplasm, most commonly found in the bladder. Cases of malignant transformation have been reported in the past, although most of them are now considered to be urothelial carcinomas with an inverted growth pattern. CASE: A 54-year-old man was diagnosed with urothelial carcinoma in situ (UCIS), high-grade papillary urothelial carcinoma (HGPUC), and IP by transurethral resection specimen of the bladder. The urothelial carcinoma cells were seen colonizing the inverted papilloma...
February 2016: Analytical and Quantitative Cytopathology and Histopathology
https://www.readbyqxmd.com/read/27363066/role-of-quercetin-in-cadmium-induced-oxidative-stress-testicular-damage-and-apoptosis-in-rats
#14
Mehmet Kanter, Tevfik Aktoz, Cevat Aktas, Filiz Ozen, Oguzhan Yarali, Betul Kanter
OBJECTIVE: The aim of this study was to investigate the role of quercetin on cadmium-induced oxidative stress, testicular damage, and apoptosis in rat testes. STUDY DESIGN: The rats were randomly allotted into 1 of 3 experimental groups: control, cadmium-treated, and cadmium-treated with quercetin; each group con- tained 10 animals. Control animals received daily injec- tions of the saline vehicle alone. The cadmium-treated group was injected subcutaneously with cadmium chloride (CdCl2) dissolved in saline at a dose of 2 mL/kg/ day for 30 days, resulting in a dosage of 1 mg/kg cadmium...
February 2016: Analytical and Quantitative Cytopathology and Histopathology
https://www.readbyqxmd.com/read/27363065/diagnostic-value-of-urine-cytology-in-bladder-cancer-a-meta-analysis
#15
Qingnan Xie, Zhen Huang, Zhiqiang Zhu, Xin Zheng, Jianwei Liu, Mengmeng Zhang, Yu Zhang
OBJECTIVE: To evaluate the diagnostic value of urine cytology in detecting bladder cancer using meta-analysis. STUDY DESIGN: Public databases, including PubMed, Embase, Springer, Elsevier Science Direct, Cochrane Library, and Google Scholar, were searched before February 2015. Sensitivity, specificity, positive likelihood ratio (LR), negative LR, and diagnostic odds ratio (DOR) of urine cytology in individual studies were calculated using random effects model or fixed effect model...
February 2016: Analytical and Quantitative Cytopathology and Histopathology
https://www.readbyqxmd.com/read/27363064/high-incidence-of-incidental-prostate-cancer-in-transurethral-resection-of-prostate-specimens-in-china-the-value-of-pathologic-review
#16
Jian Lin, Xi Yu, Xinyu Yang, Jie Jin, Liqun Zhou, Libo Liu, Jinwei Su, Yanyan Li, Meixia Shang
OBJECTIVE: To identify the incidence and clinicopathologic features of prostate cancer incidentally detected in patients undergoing transurethral resection of the prostate (TURP) for benign prostatic hyperplasia (BPH), and to estimate the clinical value of pathologic review of all TURP specimens. STUDY DESIGN: A pathologic review was performed on all TURP specimens for each patient from May 1, 2004, to June 30, 2014, in our institute. A total of 1,024 men (ages 46-98) were identified by pathology specimen...
February 2016: Analytical and Quantitative Cytopathology and Histopathology
https://www.readbyqxmd.com/read/27363063/prognostic-significance-of-mitotic-activity-in-noninvasive-low-grade-papillary-urothelial-carcinoma
#17
Ashi Kahraman Akkalp, Ömer Onur, Ümit Seza Tetikkurt, Deniz Tolga, Sule Özsoy, Ahmet Yaser Müslümanoğlu
OBJECTIVE: To identify the most useful method to detect the mitotic count (MC) by comparing different techniques, to determine a cutoff value for mitotic activity (MA), and to evaluate the correlation of this value with the recurrence of noninvasive low-grade papillary urothelial neoplasm (LGPUC). STUDY DESIGN: Hematoxylin and eosin-stained slides of 55 LGPUC cases were evaluated for their MA. MC was determined using 4 different methods. In Method 1, cases with 3 mitoses in 1 single focus of a high-power field (HPF x 400) were found, and in Method 2, cases with ≥ 5 mitoses in 1 singlefocus of an HPF, in any level of the neoplastic epithelium, were determined...
February 2016: Analytical and Quantitative Cytopathology and Histopathology
https://www.readbyqxmd.com/read/27363062/effects-of-nicotine-on-rat-tongue-mucosa-histopathological-and-immunohistochemical-analyses
#18
Veysel Eratilla, Ibrahim Uysal, Engin Deveci, Rojdan Ferman Güneş, Elif Eratilla, Ismail Yildiz, Sevda Söker
OBJECTIVE: To evaluate the histopathological and immunohistochemical effects of systemically administered nicotine on rat tongue mucosa. STUDY DESIGN: Rats were assigned to one of two groups: the experimental group received nicotine systemically (nicotine sulphate 2 mg/kg subcutaneously daily for 28 days), while the rats in the control group were administered physiological saline (1.5 mL subcutaneously for 28 days). All animals were sacrificed at the end of the study, and tongue tissue samples were removed and prepared according to routine histological procedures...
February 2016: Analytical and Quantitative Cytopathology and Histopathology
https://www.readbyqxmd.com/read/27363061/significance-of-number-and-localization-of-positive-core-biopsies-for-the-identification-of-prostate-cancer-eligible-for-active-surveillance
#19
Burkhard Helpap, Daniel Ringli, Heidrun Gevensleben
OBJECTIVE: Prostate cancer (PCa) patients fulfilling the Epstein criteria for insignificant disease are eligible for the treatment option of active surveillance (AS). Using the combined histological and cytological grading (Gleason/Helpap score), we aimed to investigate the significance of biopsy localization and tumor involvement in core needle biopsies as discriminators for insignificant cancer. STUDY DESIGN: Primary prostate biopsies of 1,285 patients were analyzed by the combined histological and cytological grading with regard to biopsy localization and tumor involvement per core...
February 2016: Analytical and Quantitative Cytopathology and Histopathology
https://www.readbyqxmd.com/read/27363060/value-of-p16-ink4a-and-ki-67-immunohistochemical-staining-in-cervical-intraepithelial-neoplasia-grade-2-biopsies-as-biomarkers-for-cervical-intraepithelial-neoplasia-grade-3-in-cone-results
#20
Ester Miralpeix, Josep M Solé-Sedeño, Gemma Mancebo, Belen Lloveras, Beatriz Bellosillo, Ramon Carreras, Francesc Alameda
OBJECTIVE: To evaluate the usefulness of p16(INK4a) (p16) and Ki-67 staining in high-grade cervical intraepithelial neoplasia (CIN2) biopsies in order to predict CIN3 results in cone specimens, thereby sparing those not likely at risk for CIN3 from unnecessary cone excision. STUDY DESIGN: We retrospectively recruited patients with CIN2 colposcopy-directed biopsy treated by loop electrosurgical excision procedure. The expression of p16 and Ki-67 was qualitatively and quantitatively analyzed in all biopsies and cone specimens...
February 2016: Analytical and Quantitative Cytopathology and Histopathology
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