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Oncoscience

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https://www.readbyqxmd.com/read/28540335/ny-eso-1-expression-in-dcis-a-new-predictor-of-good-prognosis
#1
R Charles Coombes, Otavia L Caballero, Sami Shousha, Sadaf Ghaem-Maghami, Laura Woodley-Barker, Charlotte S Wilhelm-Benartzi, A Munro Neville
BACKGROUND: At present, it is difficult to predict which patients with ductal carcinoma-in-situ (DCIS) will subsequently develop frank invasive breast cancer (IDC). A recent survey by our group has shown that NY-ESO-1 and MAGEA are both expressed in DCIS. This study was aimed at determining whether expression of these antigens was related to the later development of IDC. RESULTS: 14 of 42 (33%) of patients developed invasive breast cancer during the follow up period...
March 2017: Oncoscience
https://www.readbyqxmd.com/read/28540334/integrin-alpha10-drives-tumorigenesis-in-sarcoma
#2
EDITORIAL
Tomoyo Okada, Samuel Singer
No abstract text is available yet for this article.
March 2017: Oncoscience
https://www.readbyqxmd.com/read/28540333/metabolic-reprogramming-of-myeloid-derived-suppressive-cells
#3
EDITORIAL
Hong Du, Xinchun Ding, Cong Yan
No abstract text is available yet for this article.
March 2017: Oncoscience
https://www.readbyqxmd.com/read/28540332/hypofractionation-trials-and-radiobiology-of-prostate-cancer
#4
EDITORIAL
Sarah Gulliford, Emma Hall, David Dearnaley
No abstract text is available yet for this article.
March 2017: Oncoscience
https://www.readbyqxmd.com/read/28540331/in-silico-deconvolution-and-purification-of-cancer-epigenomes
#5
EDITORIAL
Martí Duran-Ferrer, Renée Beekman, José I Martín-Subero
No abstract text is available yet for this article.
March 2017: Oncoscience
https://www.readbyqxmd.com/read/28540330/targeting-ret-rearranged-lung-cancers-with-multikinase-inhibitors
#6
EDITORIAL
Joshua K Sabari, Evan D Siau, Alexander Drilon
No abstract text is available yet for this article.
March 2017: Oncoscience
https://www.readbyqxmd.com/read/28540329/high-setd8-inactivates-p53-in-neuroblastoma
#7
EDITORIAL
Veronica Veschi, Carol J Thiele
No abstract text is available yet for this article.
March 2017: Oncoscience
https://www.readbyqxmd.com/read/28540328/next-generation-of-cancer-immunotherapy-calls-for-combination
#8
EDITORIAL
Paola Cappello, Francesco Novelli
No abstract text is available yet for this article.
March 2017: Oncoscience
https://www.readbyqxmd.com/read/28540327/a-tcr-switchable-cell-death-pathway-in-t-all
#9
EDITORIAL
Christine Tran Quang, Benedetta Zaniboni, Jacques Ghysdael
No abstract text is available yet for this article.
March 2017: Oncoscience
https://www.readbyqxmd.com/read/28540326/sarcoma-nomograms-a-light-over-the-darkness
#10
EDITORIAL
Dario Callegaro, Rosalba Miceli, Alessandro Gronchi
No abstract text is available yet for this article.
March 2017: Oncoscience
https://www.readbyqxmd.com/read/28484729/erratum-breast-tumor-response-to-ultrasound-mediated-excitation-of-microbubbles-and-radiation-therapy-in-vivo
#11
Priscilla Lai, Christine Tarapacki, William T Tran, Ahmed El Kaffas, Justin Lee, Clinton Hupple, Sarah Iradji, Anoja Giles, Azza Al-Mahrouki, Gregory J Czarnota
[This corrects the article DOI: 10.18632/oncoscience.299.].
January 2017: Oncoscience
https://www.readbyqxmd.com/read/28484728/pretreatment-prostate-specific-antigen-doubling-time-as-prognostic-factor-in-prostate-cancer-patients
#12
Gennady M Zharinov, Oleg A Bogomolov, Natalia N Neklasova, Vladimir N Anisimov
Despite the prostate-specific antigen (PSA) serum level commonly uses as tumor marker in diagnosis of prostate cancer, it seems that PSA doubling time (PSADT) could be more useful indicator of tumor behavior and of prognosis for patients. The results of hormone and radiation therapy were evaluated for 912 prostate cancer having at least 2 PSA tests before the treatment was started. Clustering procedure (selection of homogenous group) was performed by using PSADT as the classification marker. The rate of PSADT was estimated for different dissemination rate, age, Gleasons's score and education level...
January 2017: Oncoscience
https://www.readbyqxmd.com/read/28484727/estrogens-drive-myeloid-derived-suppressor-cell-accumulation
#13
EDITORIAL
Jose R Conejo-Garcia, Kyle K Payne, Nikolaos Svoronos
No abstract text is available yet for this article.
January 2017: Oncoscience
https://www.readbyqxmd.com/read/28484726/validating-a-network-hub-in-leukaemia-stem-cells
#14
EDITORIAL
Lisa E Hopcroft, Sheela A Abraham, Tessa L Holyoake
No abstract text is available yet for this article.
January 2017: Oncoscience
https://www.readbyqxmd.com/read/28484725/nicotinamide-riboside-or-il-17a-signaling-blockers-to-prevent-liver-disorders
#15
EDITORIAL
Ana Teijeiro, Nabil Djouder
No abstract text is available yet for this article.
January 2017: Oncoscience
https://www.readbyqxmd.com/read/28105458/brg1-and-brm-loss-selectively-impacts-rb-and-p53-respectively-brg1-and-brm-have-differential-functions-in-vivo
#16
Stefanie B Marquez-Vilendrer, Sudhir K Rai, Sarah Jb Gramling, Li Lu, David N Reisman
The SWI/SNF complex is an important regulator of gene expression that functions by interacting with a diverse array of cellular proteins. The catalytic subunits of SWI/SNF, BRG1 and BRM, are frequently lost alone or concomitantly in a range of different cancer types. This loss abrogates SWI/SNF complex function as well as the functions of proteins that are required for SWI/SNF function, such as RB1 and TP53. Yet while both proteins are known to be dependent on SWI/SNF, we found that BRG1, but not BRM, is functionally linked to RB1, such that loss of BRG1 can directly or indirectly inactivate the RB1 pathway...
2016: Oncoscience
https://www.readbyqxmd.com/read/28105457/loss-of-the-swi-snf-atpase-subunits-brm-and-brg1-drives-lung-cancer-development
#17
Stefanie B Marquez-Vilendrer, Sudhir K Rai, Sarah Jb Gramling, Li Lu, David N Reisman
Inactivation of Brg1 and Brm accelerated lung tumor development, shortened tumor latency, and caused a loss of differentiation. Tumors with Brg1 and/or Brm loss recapitulated the evolution of human lung cancer as observed by the development of local tumor invasion as well as distal tumor metastasis, thereby making this model useful in lung cancer studies. Brg1 loss contributed to metastasis in part by driving E-cadherin loss and Vimentin up-regulation. By changing more than 6% of the murine genome with the down-regulation of tumor suppressors, DNA repair, differentiation and cell adhesion genes, and the concomitant up-regulation of oncogenes, angiogenesis, metastasis and antiapoptosis genes, caused by the dual loss of Brg1/Brm further accelerated tumor development...
2016: Oncoscience
https://www.readbyqxmd.com/read/28105456/cd44-a-metastasis-driver-and-therapeutic-target
#18
EDITORIAL
Joseph L Sottnik, Dan Theodorescu
No abstract text is available yet for this article.
2016: Oncoscience
https://www.readbyqxmd.com/read/28105455/mutation-hotspots-in-cis-regulatory-regions-in-cancer
#19
EDITORIAL
Rebecca C Poulos, Jason W H Wong
No abstract text is available yet for this article.
2016: Oncoscience
https://www.readbyqxmd.com/read/28105454/bet-bromodomain-inhibitor-jq1-and-tumor-angiogenesis
#20
EDITORIAL
Hemant Kumar Bid, Samuel Kerk
No abstract text is available yet for this article.
2016: Oncoscience
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