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Developmental Period Medicine

Regina Wierzejska, Katarzyna Wolnicka, Mirosław Jarosz, Joanna Jaczewska-Schuetz, Anna Taraszewska, Magdalena Siuba-Strzelińska
AIM: The aim of the study was to assess caffeine intake from cola beverages and energy drinks, as well as the consumption frequency among primary-school-age children in relation to other dietary habits. MATERIAL AND METHODS: The study included 329 children (aged 11-13 years) from five randomly selected schools in Warsaw. Caffeine intake was assessed from a food frequency questionnaire. The face-to-face interview method was selected. RESULTS: 89...
April 2016: Developmental Period Medicine
Zbigniew Kułaga, Beata Gurzkowska, Aneta Grajda, Małgorzata Wojtyło, Magdalena Góźdź, Mieczysław Litwin
UNLABELLED: The aim of this study is to estimate the prevalence of overweight and obesity in a current, nationally representative, random sample of pre-school-aged children in Poland and to compare their overweight and obesity rates with their peers from the US and Norway. MATERIAL AND METHODS: The height and weight were measured in a total of 5026 randomly sampled children aged 2-6 years and their Body Mass Index was calculated. The prevalence of overweight including obesity was determined using three definitions, i...
April 2016: Developmental Period Medicine
Grażyna Krzemień, Agnieszka Szmigielska, Przemysław Bombiński, Marzena Barczuk, Agnieszka Biejat, Stanisław Warchoł, Teresa Dudek-Warchoł
BACKGROUND: Hydronephrosis is the one of the most common congenital abnormalities of urinary tract. The left kidney is more commonly affected than the right side and is more common in males. AIM OF THE STUDY: To determine the role of ultrasonography, renal dynamic scintigraphy and lowerdose computed tomography urography in preoperative diagnostic workup of infant with extreme hydronephrosis. CASE REPORT: We presented the boy with antenatally diagnosed hydronephrosis...
April 2016: Developmental Period Medicine
Elżbieta Krzesiek, Barbara Iwańczak, Urszula Zaleska-Dorobisz, Dariusz Patkowski
Hematoma duodenum is a very rare complication of diagnostic endoscopy of the upper gastrointestinal tract when biopsy of the duodenum is performed (average frequency is estimated as 1:1,250 biopsies). Most often, it affects children and young adults without any risk factors. Symptoms result from obstruction of the duodenum and compression of the adjacent structures. Conservative treatment, which consists of parenteral nutrition and aspiration of gastric contents until the absorption of hematoma and patency of the gastrointestinal tract returns, is preferred...
April 2016: Developmental Period Medicine
Dorota Lewartowska-Nyga, Grażyna Skotnicka-Klonowicz
Head injuries in children, especially minor head injuries, still constitute a important diagnostic and therapeutic problem. Despite progress in medical sciences, there is no definition of minor head injury or standards of the management of children with a minor head injury. In consequence, the diagnostic procedure in the child who does not show any signs of central nervous system damage as a result of head injury is individual and depends on the experience and knowledge of the aid provider and as well as procedures established in a given ward...
April 2016: Developmental Period Medicine
Ryszard Lauterbach, Ewa Kamińska, Piotr Michalski, Jan Paweł Lauterbach
Lactoferrin is an iron-binding glycoprotein, which is present in most biological fluids with particularly high levels in colostrum and in mammalian milk. Bovine lactoferrin is more than 70% homologous with human lactoferrin. Most of the clinical trials have used bovine lactoferrin for supplementation. This review summarizes the recent advances in explaining the mechanisms, which are responsible for the multifunctional roles of lactoferrin, and presents its potential prophylactic and therapeutic applications...
April 2016: Developmental Period Medicine
Hanna Mierzewska, Magdalena Mierzewska-Schmidt, Gajja S Salomons, Magdalena Dudzińska, Elżbieta Szczepanik
Alexander Disease (ALXDRD) is an autosomal dominant leukodystrophy caused by mutation in one allele of GFAP gene, encoding glial fibrillary acidic protein (GFAP). Most cases occur due to de novo. There are three clinical subtypes of ALXDRD: infantile, juvenile and adult form, but congenital form is also outlined. The disease's spectrum comprises of macrocephaly, progressive pyramidal signs, and seizures in congenital and infantile subtypes. Neuropathologically are enormous number of Rosenthal fibers (RF) mainly around vessels, in subependymal and subpial regions are found...
April 2016: Developmental Period Medicine
Agnieszka Szmigielska, Grażyna Krzemień, Maria Roszkowska-Blaim, Ewa Obersztyn
UNLABELLED: The prevalence of obesity in children is still rising all over the world. The most common reason for significant weight gain is a high-calorie diet and decreased physical activity. However, apart from environmental factors, genetic predisposition plays a crucial role in the pathomechanism of obesity. We present the case of a boy with pathological obesity and Bardet-Biedl syndrome (BBS). BBS is a ciliopathy, a heterogeneous group of rare disorders associated with defects in primary cilia...
April 2016: Developmental Period Medicine
Agnieszka Stembalska, Izabela Łaczmańska, Justyna Gil, Karolina A Pesz
BACKGROUND: Fragile X syndrome (FXS), one of the manifestations of FMR1-related disorders, is one of the most frequent genetic causes of intellectual disability. In over 99% of all cases it results from the expansion of CGG repeats in the 5'-untranslated region of the FMR1 gene and presents in males and in about 50% of the females with an FMR1 full mutation, usually with a milder phenotype. OBJECTIVE: Although the morphologic and behavioral phenotype in males is a well-recognized entity, the presentation in females is variable and not as specific...
April 2016: Developmental Period Medicine
Beata Modzelewska
One hundred and twenty years after the description of extracts from the adrenal medulla, the use of beta-blockers and beta-agonists evolved from antianginal drugs and tocolytics to ligand-directed signaling. Beta-blockers in the fields of obstetrics and gynecology have so far been limited to the consideration of continuing treatment of disorders of the cardiovascular system and other dysfunctions that started before pregnancy. Studies in recent years have shown that beta-adrenoceptor signaling might be crucial in carcinogenesis and metastasis, apoptosis and anoikis...
April 2016: Developmental Period Medicine
Inga Brzozowska, Iwona Sikorska
The literature review regarding potential effects of screen media on cognitive development among children under 3 years old, is presented. In this article, cognitive aspects of development include acquisition of language, attention, learning and later school performance. The constant increase of children's access to television is noted, indicating that 60% of infants and toddlers watch TV regularly for 1-2 hours per day. The review included 40 articles and book chapters of significant such as Anderson, Barr, Christakis, Zimmerman, Meltzoff, Courage, Setliff, Troseth...
January 2016: Developmental Period Medicine
Anna Lis-Święty, Dorota Milewska-Wróbel, Irmina Janicka
The paper refers to the recently published empirical data and systematic reviews on the impact of diets, foods, nutrients and bioactive substance exposures in pregnancy and in early infancy, on the development of atopic disorders. The results of studies referring to a broad range on dietary factors are mostly conflicting. There are several limitations of these researches. Based on the existing information, it is not possible to establish the role of antioxidants and vitamin D supplementation in atopic disease development...
January 2016: Developmental Period Medicine
Paulina Grzesiak, Monika Słupecka-Ziemilska, Jarosław Woliński
In this article we present the results of recent studies on the mechanism of action and biological role of α-ketoglutaric acid (AKG) in animals including developmental period of life. AKG is an intermediate in the Krebs cycle, which generates energy for life processes. Administration of AKG has been shown to be beneficial for proper development and function of the skeletal system during growth of young organisms, as well as in adulthood. In the form of a dietary supplement it also contributes to inhibition of osteoporosis in women...
January 2016: Developmental Period Medicine
Jarosław Woliński, Monika Słupecka-Ziemilska, Maria Boryczka, Paulina Grzesiak, Jakub Kwiatkowski, Grzegorz Kotarba
Since the beginning of the 20th century, researchers have been working to improve the understanding of gastrointestinal motility. The first major discovery was the observation of a migrating myoelectric complex that turned out to be a universal occurrence among vertebrates. Further inquires resulted in a detailed description of its development during different stages of ontogeny. Some time before that, a cornerstone had been laid for a breakthrough that would come years later. That cornerstone came in the form of interstitial cells of Cajal whose true role could not be discerned until the discovery of a CD117 receptor - their main marker...
January 2016: Developmental Period Medicine
Agata Marcinkowska-Mituś, Anna Mizerska-Żurowska, Maria Mituś-Kenig, Magdalena Łoboda, Elżbieta Pawłowska
AIM: The aim of the work is to determine the significance of posterior relationship between the first upper and lower molars from the palatal side in diagnosing Class II malocclusions. MATERIAL AND METHODS: One hundred and fifty diagnostic models and lateral cephalograms of patients from the Zbigniew Żak District Memorial Outpatient Clinic in Cracow were assessed. RESULTS: Out of 150 patients, skeletal Class II was diagnosed in 108 patients based on measuring the ANB angle (>4°), and in 115 patients based on the Wits appraisal (≥2 mm)...
January 2016: Developmental Period Medicine
Jacek Podogrodzki, Michał Lebiedowski, Mieczysław Szalecki, Izabela Kępa, Małgorzata Syczewska, Sergiusz Jóźwiak
UNLABELLED: The aim of this study was to objectively assess the impact of low level laser therapy on skin blood flow, in terms of two of its components - the flow and trophic and therapeutic effect. MATERIAL AND METHODS: Nineteen children aged 3-15 years have been included in the study (seven boys and twelve girls) with a diagnosis of meningomyelocele in the lumbosacral area. In nine of them (47.3%) bedsores were found in the area of paresis location. Studies of skin blood flow were performed using xenon 133 clearance in the Department of Nuclear Medicine of the Children's Memorial Health Institute...
January 2016: Developmental Period Medicine
Izabela Tabak, Joanna Mazur
INTRODUCTION: One reason of increased psychological and somatic health problems in adolescence is intensification of stress in school and everyday life. There is little evidence to what extent the level of school achievements shapes this relationship. AIM: The aim of the study was to investigate determinants of subjective health complaints in schoolaged children, taking into account the interaction effects. METHODS: Anonymous survey was conducted in Poland in 2013/2014 on the sample of 4,545 students, as a part of the HBSC (Health Behaviour in School-aged Children) study...
January 2016: Developmental Period Medicine
Grażyna Krzemień, Agnieszka Szmigielska, Katarzyna Jankowska-Dziadak, Małgorzata Pańczyk-Tomaszewska
Urolithiasis in children occurs with the incidence of 0.1-5%. Risk factors such as metabolic disorders, recurrent urinary tract infections and/or congenital abnormalities of urinary tract are detected in 75-85% of children with urolithiasis. Staghorn calculi is associated with delayed diagnosis and treatment of urinary tract infection caused by specific organisms, which produce the enzyme urease, promoting generation of ammonia and hydroxide from urea. We present two boys with staghorn calculi recognized in 8th and 31st month of age...
January 2016: Developmental Period Medicine
Elżbieta Kuźma-Mroczkowska, Małgorzata Pańczyk-Tomaszewska, Piotr Skrzypczyk, Iwona Artemiuk, Maria Roszkowska-Blaim
BACKGROUND: Aim of the study was to evaluate factors affecting body mass change in children with idiopathic nephrotic syndrome (INS) during 6-months treatment of initial disease bout with glucocorticoids (GC). MATERIAL AND METHODS: We studied 31 children with INS (22♂, 9♀, 3.6±1.8 years) treated during 6 months with GC due to initial INS bout and 31 control healthy children (18♂, 13♀, 4.0±1.8 years). Following factors were evaluated: body mass, body mass index (BMI), BMI Z-score, gender, age, gestational age at birth, birth weight, GC dose, parental age and BMI, time spent for TV/computer, physical activity, place of residence...
January 2016: Developmental Period Medicine
Dirk Wildemeersch, Norman D Goldstuck, Thomas Hasskamp
Immediate postpartum intrauterine device (IUD) insertion deserves great attention as it can provide immediate, timely and convenient contraception plus the added benefit of preventing repeat unintended pregnancies. Although women post vaginal delivery can benefit from immediate post-placenta contraception, women undergoing Cesarean section clearly need contraception, as an inter-delivery interval shorter than 18 months places them at a high risk for uterine rupture. The main drawback of currently available framed IUD devices for immediate postpartum insertion of an IUD is their high expulsion and displacement rates when inserted immediately postpartum after both vaginal and Cesarean delivery...
January 2016: Developmental Period Medicine
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