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Developmental Period Medicine

Przemysław Bombiński, Michał Brzewski, Stanisław Warchoł, Marek Gołębiowski
BACKGROUND: Low-dose CT Urography (LD-CTU) has become a standard procedure in urinary tract abnormalities in children, especially when MR Urography is not available. Standard one-phase CTU is performed in excretory phase. There is also a split-bolus technique, which combines two or even three phases during one scan and provides more clinical information without higher radiation exposure. It can be implemented for congenital anomalies of kidneys and urinary tract (CAKUT) in children, however, this application is not deeply discussed in scientific literature...
2017: Developmental Period Medicine
Tamara Zofia Walczak, Magdalena Chrzan-Dętkoś
AIM: The aim of the study was to examine the relationship between anxiety, the severity of post-traumatic stress disorder (PTSD) symptoms in mothers and hot and cool executive functions of their children who were born very prematurely. MATERIAL AND METHODS: The group consisted of 20 mothers and their children born before 32 weeks of pregnancy. The intensity of anxiety in mothers was measured using the State-Trait Anxiety Inventory (STAI), while the severity of symptoms of PTSD was assessed using the Impact of Event Scale - Revised (IES-R)...
2017: Developmental Period Medicine
Jayesh Desale, Hemanshi Shah, Vikrant Kumbhar, Gursev Sandlas
Desmosis coli is a rare pathology presenting as slow transit constipation. In this case we would like to discuss the presentation and management of desmosis coli. A 14-month-old female hailing from western India with a history of chronic constipation presented with acute massive abdominal distension and vomiting. At laparotomy, a hugely dilated transverse and sigmoid colon with a transition zone at the lower sigmoid was found. A transverse stoma was done after taking multiple sero-muscular biopsies. The patient underwent re-exploration on day 14 because of the non-functioning of the stoma and a fixed bowel loop...
2017: Developmental Period Medicine
Nikolay A Shcherbina, Liudmyla А Vygivska
OBJECTIVES: To study the state of immunity in pregnancies associated with urogenital infection and complicated by intrauterine infection. MATERIAL AND METHODS: The comparative study involved the examination of 250 pregnant women with urogenital infection and ultrasonographic signs of intrauterine infection and their newborns in order to assess the state of cellular and humoral immunity components and nonspecific resistance. A direct prospective examination of pregnant women was carried out in the 2nd and 3rd trimesters of gestation...
2017: Developmental Period Medicine
Grażyna Krzemień, Agnieszka Turczyn, Małgorzata Pańczyk-Tomaszewska, Aleksandra Jakimów-Kostrzewa, Agnieszka Szmigielska
In patients with autosomal dominant polycystic kidney disease (ADPKD) coexisting abnormalities of the urinary tract are considered rare. Only a few patients with ADPKD and congenital abnormalities of the kidney and urinary tract- renal agenesis, hypoplasia, aplasia, horseshoe kidney, ectopic multicystic dysplasic kidney, or subpelvic junction obstruction were reported. Renal agenesis occurs in approximately 1 in 1.500.000-3.000.000 patients with ADPKD. We report a boy with ADPKD and renal agenesis diagnosed at the age of 12 years...
2017: Developmental Period Medicine
Katarzyna Walicka-Serzysko, Magdalena Postek, Dorota Sands
Small airways are the site of pathological changes often in an early stage in many diseases such as asthma or cystic fibrosis. However this part of the airways is overlooked in conventional respiratory function tests and it is therefore often referred to as "silent lung zone". This paper presents the theoretical background of MBNW multi-breath nitrogen washout in the diagnosis of minor respiratory diseases. The technical issues related to the preparation of pediatric patients for the test. Clinical applications of the MBNW test results are still subject to a number of studies...
2017: Developmental Period Medicine
Nina Mól, Magdalena Zasada, Małgorzata Klimek, Przemko Kwinta
AIM: To continue the prospective follow-up cohort study on the somatic development and lipid metabolic parameters of 11-year-old-children born with extremely low birth weight and to compare them with the results obtained in the study of 7-year-old children from the same group. MATERIAL AND METHODS: 204 newborns with birth weight ≤1000 g were born in the Malopolska voivodship between 1.09.2002 and 31.08.2004. From this group 115 (56%) children died during infancy and 89 (44%) infants survived...
2017: Developmental Period Medicine
Joanna Żółkowska, Kamil K Hozyasz, Maria Nowacka
Phenylketonuria (PKU) is the autosomal recessive deficiency of phenylalanine hydroxylase resulting in the accumulation of phenylalanine (Phe) in blood and in the brain. Phe restriction in a patient's diet is determined depending on the amount of Phe intake which allows for stable blood Phe levels within the therapeutic range of 120-360µmol/L. In clinical practice the empirical determination of Phe tolerance relies on frequent assessment of blood Phe concentrations in relation to Phe intake from food records...
2017: Developmental Period Medicine
Mateusz Jagła, Anna Peterko, Katarzyna Olesińska, Izabela Szymońska, Przemko Kwinta
INTRODUCTION: Retinopathy of prematurity (ROP) is one of the leading avoidable causes of blindness in childhood in developed countries. Accurate diagnosis and treatment are essential for preventing the loss of vision. WINROP ( is an online monitoring system which predicts the risk for ROP requiring treatment based on gestational age, birth weight, and body weight gain. AIM: To validate diagnostic accuracy of the WINROP algorithm for the detection of severe ROP in a single centre cohort of Polish, high-risk preterm infant population...
2017: Developmental Period Medicine
Ewa Helwich, Magdalena Rutkowska, Renata Bokiniec, Ewa Gulczyńska, Roman Hożejowski
BACKGROUND: Intraventricular hemorrhage (IVH) is a common pathology in preterm infants with extremely and very low birth weight. It is particularly often seen in newborns with Respiratory Distress Syndrome (RDS). AIM: To assess the incidence of IVH in preterm newborns with RDS treated with surfactant, and to identify factors that might reduce the risk of IVH in this population. MATERIAL AND METHODS: This multicenter, prospective cohort study is part of the "Neo-pro" study project...
2017: Developmental Period Medicine
Dorota Hoffman-Zacharska, Paulina Górka-Skoczylas
Epilepsy is common neurological condition affecting 0.8-1% of the human population. Since 80% of patients are under 20 years of age, it is mainly a disease of the developmental period. The causes of epilepsy are heterogeneous, but the disease has always been considered a genetic disorder, which no longer doubted. Epilepsy genetics has undergone a revolution since the discovery of the first gene responsible for epilepsy. This is mainly because of introduction of the next generation sequencing as research and diagnostic tool, and transition from studies of pedigrees with epilepsy to the analysis of cases of epileptic encephalopathies...
2017: Developmental Period Medicine
Henning Schneider
Placental pathology is associated with major pregnancy disorders and the concept of the Great Placental Syndromes encompasses disorders of placentation, such as preeclampsia with and without fetal growth restriction, preterm labor, preterm premature rupture of membranes, late spontaneous abortion, and placental abruption. Preeclampsia is divided between the early and late onset variety and placental dysfunction is a central feature in the pathogenesis of both. In the early onset type, syncytiotrophoblastic stress seems to be related to an inherent defect of the trophoblast...
2017: Developmental Period Medicine
Piotr Polaczek
No abstract text is available yet for this article.
2017: Developmental Period Medicine
Agnieszka Zachurzok, Anna Springwald, Piotr Gibała, Paweł Matusik
The present paper is a review of current knowledge concerning the most appropriate strategy in the conservative therapy of obese children and adolescents. It presents an account of the combined mode of therapy consisting of behavioral and dietary counseling with appropriate physical activity (also using the support of modern media and devices). The rise in obesity is usually a long-lasting process involving genetic predispositions but also environmental factors which can be modified. The treatment of obesity should be focused on these modified factors and be a lifelong treatment, not merely a short period of exercise or a diet program...
2017: Developmental Period Medicine
Halina Weker, Marta Barańska, Agnieszka Riahi, Małgorzata Strucińska, Małgorzata Więch, Grażyna Rowicka, Hanna Dyląg, Witold Klemarczyk, Agnieszka Bzikowska, Piotr Socha
INTRODUCTION: Children's appropriate dietary pattern determines their optimal development, reduces the risk of childhood diseases and the risk of diet-dependent diseases, including obesity in adulthood. AIM: To analyze the dietary patterns of children with excess weight aged 1-3 years in comparison with the main components of the safe nutrition model including: the organization of meals (frequency of meals), selection of products (food intake), energy and nutritional value of children's diets...
2017: Developmental Period Medicine
Joanna Gajewska, Jadwiga Ambroszkiewicz, Halina Weker, Magdalena Chełchowska
INTRODUCTION: Although lipid peroxidation products are formed during normal cell metabolism, they appear mostly in pathological conditions via producing an excess of free radicals that can react with unsaturated fatty acids, in particular low-density lipoprotein (LDL). The aim of this study was to investigate the relations between oxidized LDL (oxLDL), the fat-soluble vitamin status and the anthropometric parameters in prepubertal obese children. MATERIAL AND METHODS: Thirty-two obese (SDS-BMI >2) and 25 non-obese children (SDS-BMI <-1+1>) were included in the study...
2017: Developmental Period Medicine
Alicja Karney, Hanna Brągoszewska, Leszek Soluch, Mariusz Ołtarzewski
Obesity in children causes metabolic and structural changes in blood vessels which lead to the development of cardiovascular diseases and type 2 diabetes. AIM: The aim of the study was to assess the risk factors for atherosclerosis in obese children studied in the One-Day Hospitalization Department of the Institute of Mother and Child. MATERIAL AND METHODS: The study included 75 children aged 6-12 years (36 boys, 39 girls) with aBMI>97th percentile. The control group consisted of 36 children aged 5-10 years (18 boys, 18 girls) with a BMI of 75-90...
2017: Developmental Period Medicine
Maria Jodkowska, Anna Oblacińska, Hanna Nałęcz, Joanna Mazur
THE AIM: to identify the barriers to engaging in physical activity that are perceived by adolescents with overweight and obesity, and to establish whether a correlation exists among the barriers they perceive and the health-oriented motivation for undertaking physical activity. MATERIAL AND METHODS: The study was conducted on a representative sample of 2,300 students aged 13-16 years. The data was collected through an anonymous survey. Young people were asked about their body weight and height, the barriers to physical activity and the health-related motives to engaging in it...
2017: Developmental Period Medicine
Dorota Kleszczewska, Anna Dzielska, Hanna Nałęcz, Joanna Mazur
BACKGROUND: The wrong subjective assessment of body mass may have consequences for the health, quality of life and proper functioning of adolescents in society. AIM: The purpose of the study is to provide a detailed analysis of the discrepancies between the objective and subjective assessment of body mass by 15-year-old boys and girls in Poland against the background of international statistics and to assess the effect of physical activity on the level and directions of these discrepancies...
2017: Developmental Period Medicine
Wiesław Osiński, Adam Kantanista
Overweight and obesity may lead to serious health problems, and negatively affect everyday functioning in physical, psychological and social spheres. The high prevalence of overweight and obesity in children and adolescents constitutes a huge public health burden. One way of designing and implementing behavioral interventions aimed at the reduction of adipose tissue is to promote physical activity. In this review we present recommendations regarding the planning, monitoring and implementation of intervention programs involving controlled physical activity...
2017: Developmental Period Medicine
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