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Ophthalmology and Therapy

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https://www.readbyqxmd.com/read/28444515/cataract-surgery-in-patients-with-a-previous-history-of-kamra-inlay-implantation-a-case-series
#1
Majid Moshirfar, Tyler S Quist, David F Skanchy, Steven H Linn, Jordan Desautels, Phillip C Hoopes
INTRODUCTION: The visual outcome of cataract surgery in patients with a previous history of KAMRA inlay implantation is an emerging issue for which limited research exists. The purpose of this study is to describe postoperative visual outcomes in this patient population. METHODS: This is a case series with retrospective chart review. Seven patients underwent cataract surgery following KAMRA corneal inlay implantation. Visual acuity was assessed before and after cataract surgery...
April 25, 2017: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/28391446/a-review-of-current-and-future-management-of-geographic-atrophy
#2
REVIEW
Riccardo Sacconi, Eleonora Corbelli, Lea Querques, Francesco Bandello, Giuseppe Querques
Age-related macular degeneration (AMD) is a multifactorial disease and a leading cause of vision impairment in elderly people in Western society. Geographic atrophy (GA), the late stage of dry AMD, is typically defined as a round or oval area of atrophy of 175 µm or more. In GA patients, visual acuity (VA) can still be good if the macula is spared, but decreased if GA extends through the fovea causing a great impairment of quality of life. Because of a poor correlation between VA and GA lesions or progression, a multimodal imaging approach is necessary to better follow up GA patients...
April 8, 2017: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/28390052/a-review-of-presbyopia-treatment-with-corneal-inlays
#3
REVIEW
M Amir Moarefi, Shamik Bafna, William Wiley
The prevalence of presbyopia continues to increase every year. The therapeutic approaches to presbyopia cover the spectrum of non-surgical to surgical techniques. With recent advances in biocompatible materials, corneal inlays make a strong case for their place within the treatment spectrum. This article takes a closer look at three of the current corneal inlay models: KAMRA, Raindrop, and Presbia Flexivue Microlens. Each design approach and mode of action is described with data from key clinical trials. Furthermore, the ability to choose the most suitable corneal inlay is presented by comparing each model and identifying their similarities and differences...
April 7, 2017: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/28357601/a-review-of-microinvasive-combined-phaco-vitrectomy-recent-technical-advances
#4
REVIEW
Andrea Mercanti, Antonio Renna
Combined cataract and vitreoretinal surgery results in better compliance in patients with posterior segment pathology and should be the preferred approach to reduce the high rate of cataract development after vitreoretinal surgery and to improve earlier visual acuity. Technological advances in both anterior and posterior segment surgery are leading to the development of instruments with a smaller diameter and more efficient tools, resulting in a minimizing of the tissue trauma related to the surgery, acceleration of functional recovery and increasing patient comfort...
March 29, 2017: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/28324452/a-review-of-ranibizumab-for-the-treatment-of-diabetic-retinopathy
#5
REVIEW
Michael W Stewart
INTRODUCTION: Laser photocoagulation has been the standard treatment for diabetic macular edema (DME) and proliferative diabetic retinopathy (PDR) for several decades. The discovery of vascular endothelial growth factor (VEGF) and the subsequent determination of its critical role in the development DME and PDR has led to the development of VEGF inhibitory drugs. Ranibizumab was the first anti-VEGF drug approved for the treatment of both DME and diabetic retinopathy in eyes with DME. METHODS: Medline searches with the keywords "ranibizumab," "diabetic macular edema," and "proliferative diabetic retinopathy" were performed to identify pertinent pre-clinical studies and clinical trials...
March 21, 2017: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/28258400/a-review-of-selective-laser-trabeculoplasty-recent-findings-and-current-perspectives
#6
REVIEW
Yujia Zhou, Ahmad A Aref
Selective laser trabeculoplasty (SLT) has been widely used in the clinical management of glaucoma, both as primary and adjunctive treatment. As new evidence continues to arise, we review the current literature in terms of indications and efficacy, surgical technique, postoperative care, repeatability, and complications of this therapy. SLT has been shown to be effective in various glaucomas, including primary open-angle glaucoma (POAG), normal-tension glaucoma (NTG), steroid-induced glaucoma, pseudoexfoliation glaucoma (PXFG), and primary angle-closure glaucoma (PACG), as well as other glaucoma subtypes...
March 3, 2017: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/28210962/giant-cell-tumor-of-the-frontal-bone-presenting-as-an-orbital-mass
#7
Peter H Tang, Pradeep Mettu, Amanda C Maltry, Andrew R Harrison, Ali Mokhtarzadeh
A 10-year-old male was referred for evaluation of a right orbital mass present for 3 weeks with associated tenderness to palpation. Magnetic resonance imaging (MRI) and computed tomography imaging (CT) revealed a solid mass centered in the frontal bone with extension into the orbit. Surgical excision and histologic analysis of the lesion was consistent with a diagnosis of a Giant Cell Tumor (GCT) of the frontal bone. The patient tolerated the procedure without complication and is doing well upon follow-up.
February 16, 2017: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/28188490/a-review-of-laser-assisted-versus-traditional-phacoemulsification-cataract-surgery
#8
REVIEW
H Burkhard Dick, Tim Schultz
The use of femtosecond laser surgery improves the precision and reproducibility of corneal incisions and the capsular opening; it also reduces the amount of ultrasound energy required for lens nucleus work-up. The rate of complications reported so far appears to be low. There are a number of contraindications such as a history of cornea and/or glaucoma surgery and certain anatomical features like deep-set eyes, kyphosis, tremor, and obesity. Visual recovery and refractive results of both techniques are excellent...
February 10, 2017: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/28185205/a-review-of-subthreshold-micropulse-laser-and-recent-advances-in-retinal-laser-technology
#9
REVIEW
Daniel Su, Jean-Pierre Hubschman
The role of retinal photocoagulation as a first line therapy for various retinal pathologies has decreased with the introduction of anti-vascular endothelial growth factor therapy. However, retinal laser therapy remains an important treatment modality, especially with the emergence of micropulse subthreshold treatment and the integration of newer technology such as augmented reality and semi-automated delivery. This review summarizes current evidence for micropulse laser as a treatment modality and discusses the role of new technology such as augmented reality in the future of laser therapy...
February 9, 2017: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/28160249/evaluation-of-iontophoretic-collagen-cross-linking-for-early-stage-of-progressive-keratoconus-compared-to-standard-cross-linking-a-non-inferiority-study
#10
Alina Cantemir, Anisia I Alexa, Nicoleta Anton, Roxana E Ciuntu, Ciprian Danielescu, Dorin Chiselita, Danut Costin
INTRODUCTION: The purpose of this study was to evaluate the efficacy and safety of iontophoretic collagen cross-linking (I-CXL) compared to epithelium-off standard collagen cross-linking (CXL) in treating the early stages of progressive keratoconus. METHODS: This retrospective cohort study at Oftaprof Clinic, Iasi, Romania included 40 eyes of 40 patients with progressive keratoconus stage I according to the Amsler classification who underwent I-CXL and the results were compared with a matched group of 40 eyes from 40 patients who received standard CXL...
February 3, 2017: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/28160248/gas-tamponade-for-retinectomy-in-pvr-related-retinal-detachments-a-retrospective-study
#11
Vasileios T Papastavrou, Irini Chatziralli, Dominic McHugh
INTRODUCTION: The purpose of the study was to evaluate the anatomical and functional results in patients with proliferative vitreoretinopathy (PVR) treated with retinectomy and perfluoro-octane gas (C3F8) as a tamponade agent. METHODS: 12 patients with inferior and anterior complicated PVR-related retinal detachment, who were treated with retinectomy, where C3F8 was used as the tamponade agent were examined. Primary outcome was the anatomical success, while visual acuity, existence of an epiretinal membrane (ERM) and intraocular pressure (IOP) postoperatively were secondary outcomes...
February 3, 2017: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/28155208/comparison-between-botulinum-toxin-a-injection-and-lacrimal-punctal-plugs-for-the-control-of-post-lasik-dry-eye-manifestations-a-prospective-study
#12
Sameh M Fouda, Hala K Mattout
INTRODUCTION: Laser in situ keratomelieusis (LASIK) is one of the commonest refractive procedures performed nowadays. The dry eye problem is nearly universal in all patients after LASIK and it can be so annoying that the post-operative patient satisfaction is sometimes precluded. Conventional treatment includes the use of artificial tears. Alternative methods such as punctal plugs and botulinum toxin injection can be used for the management of post-LASIK dry eye. The aim of this study is to compare botulinum toxin injection in the orbicularis muscle to lacrimal punctal plugs for the control of post-LASIK dry eye manifestations...
February 2, 2017: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/27909980/omalizumab-in-severe-refractory-vernal-keratoconjunctivitis-in-children-case-series-and-review-of-the-literature
#13
Serge Doan, Flore Amat, Eric Gabison, Sarah Saf, Isabelle Cochereau, Jocelyne Just
INTRODUCTION: Vernal keratoconjunctivis (VKC) is a severe form of pediatric ocular allergy, characterized by acute and chronic corneoconjunctival inflammation that may lead to visual sequelae. Although topical immunosuppressive drugs such as cyclosporine are usually effective, some severe forms may be refractory and require prolonged steroid therapy. Very few papers report the use of omalizumab in VKC in the literature. In the present study, we describe our clinical experience with omalizumab in severe VKC children...
December 1, 2016: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/27837409/need-for-animal-models-of-meibomian-gland-dysfunction
#14
Louis Tong, Preeya K Gupta
Evaporative dry eye has gained increasing interest in recent years in academia, pharmaceutical, and medical device industries. The main cause of this type of dry eye is attributed to meibomian gland dysfunction (MGD). MGD is a diffuse abnormality of the meibomian glands characterised by terminal duct obstruction and eventually leading to signs and symptoms of dry eye. There have been only a few reported animal models of MGD, but recent advances are likely to lead to new models and better ways to assess the pathology in these animals...
December 2016: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/27815721/erratum-to-newly-diagnosed-primary-open-angle-glaucoma-randomized-to-2-trabecular-bypass-stents-or-prostaglandin-outcomes-through-36-months
#15
Steven D Vold, Lilit Voskanyan, Manfred Tetz, Gerd Auffarth, Imran Masood, Leon Au, Iqbal Ike K Ahmed, Hady Saheb
No abstract text is available yet for this article.
December 2016: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/27744531/uveitis-specialists-and-rheumatologists-select-different-therapies-for-idiopathic-non-necrotizing-anterior-scleritis
#16
Daniel J Ozzello, Jason R Kolfenbach, Alan G Palestine
INTRODUCTION: Uveitis specialists and rheumatologists treat patients with anterior scleritis, but data from controlled trials to guide management are scarce, making differences in treatment paradigms possible. METHODS: 1044 uveitis specialists and rheumatologists were surveyed regarding therapy for a patient with anterior scleritis. Respondents were asked to select first- and second-choice therapies and then reselect therapies assuming that the costs of all options were equal and that insurance approval was ensured...
December 2016: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/27709441/correlation-between-intraocular-pressure-and-central-corneal-thickness-in-persian-children
#17
Mahmood Nejabat, Fatemeh Heidary, Mohammad Reza Talebnejad, Ramin Salouti, Mohammad Hossein Nowroozzadeh, Masoumeh Masoumpour, Hamideh Mahdaviazad, Zahra Tajbakhsh, Maryam Keshtkar, Hossein Jamali, Mohammad Reza Khalili, Hossein Movahedan, Narges Roustaei, Reza Gharebaghi
INTRODUCTION: This study aimed to determine intraocular pressure (IOP) and central corneal thickness (CCT) measurements in healthy Persian children to find clinical reference values in this ethnicity. Additionally, we examined the possible relationship between these measurements. METHODS: This cross-sectional study included 262 eyes of 131 Persian primary school children between 6 and 13 years of age. All eyes were healthy and had no anterior or posterior segment abnormalities, corneal disease, or evidence of glaucoma...
December 2016: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/27638839/combined-glaucoma-tube-shunt-ahmed-and-fluocinolone-acetonide-retisert%C3%A2-implantation-compared-to-ahmed-alone-in-uveitic-glaucoma
#18
Mark Zivney, Phoebe Lin, Beth Edmunds, Mansi Parikh, Hana Takusagawa, Shandiz Tehrani
INTRODUCTION: Glaucoma is a known complication of uveitis, and may require glaucoma tube shunt implantation for intraocular pressure (IOP) control. The success of glaucoma tube shunt implantation in the setting of a local ocular steroid depot in uveitic glaucoma remains unknown. The purpose of this study was to determine whether patients who underwent combined glaucoma tube shunt (Ahmed) and fluocinolone acetonide (Retisert™, Bausch + Lomb, Bridgewater, NJ, USA) implantation have superior outcomes compared to patients with Ahmed implants only in the setting of uveitic glaucoma...
December 2016: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/27619226/ocriplasmin-for-treatment-of-vitreomacular-traction-an-update
#19
REVIEW
Mohammed Ali Khan, Julia A Haller
Pharmacologic vitreolysis with ocriplasmin, a 27 kilodalton serine protease, is an effective nonsurgical treatment option for vitreomacular traction (VMT). Data from phase III clinical studies, including the Microplasmin for Intravitreal Injection-Traction Release without Surgical Treatment (MIVI-TRUST) and Ocriplasmin for Treatment for Symptomatic Vitreomacular Adhesion Including Macular Hole (OASIS) studies, have demonstrated the treatment efficacy of ocriplasmin for VMT and full-thickness macular hole (FTMH)...
December 2016: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/27619225/newly-diagnosed-primary-open-angle-glaucoma-randomized-to-2-trabecular-bypass-stents-or-prostaglandin-outcomes-through-36-months
#20
Steven D Vold, Lilit Voskanyan, Manfred Tetz, Gerd Auffarth, Imran Masood, Leon Au, Iqbal Ike K Ahmed, Hady Saheb
PURPOSE: To examine outcomes through 36 months in phakic eyes with newly diagnosed primary open-angle glaucoma (POAG) naïve to therapy randomized to treatment with two trabecular micro-bypass stents or topical prostaglandin. METHODS: Subjects with POAG naïve to therapy, with intraocular pressure (IOP) ≥21 and ≤40 mmHg, were randomized to implantation of two stents or travoprost. Additional medication was to be prescribed post-treatment for elevated IOP or glaucomatous optic nerve findings...
December 2016: Ophthalmology and Therapy
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