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Ophthalmology and Therapy

Majid Moshirfar, Yanning Ding, Yasmyne Ronquillo, Orry C Birdsong, Michael S Murri
Ultramarathon-associated corneal edema is a rare phenomenon. We report a case of a patient who presented with bilateral corneal edema following an ultramarathon. The corneal edema resolved without sequelae 48 h later. The authors hypothesize that the additive effect of enhanced glycolysis, an increased lactate level in the aqueous humor, and oxidative stress alters the normal endothelial regulation of the cornea and leads to corneal edema.
March 13, 2018: Ophthalmology and Therapy
Alexander James Brent, Abdul R El-Khayat, Shamfa A M Peart, Somnath Banerjee
The purpose of this report is to describe the case and management of an unexplained vitreous haemorrhage that occurred after repeated roller-coaster riding. The authors inadvertently demonstrate the value of observation over immediate surgery in certain situations and review the literature on vitreoretinal and other ocular complications after roller-coaster riding. A 26-year-old male presented 12 h after riding high-velocity roller-coasters with a left vitreous haemorrhage. A hazy view of the retina and B-scan revealed a bullous area of superior-temporal retinal lifting...
March 9, 2018: Ophthalmology and Therapy
Clare F McCloskey, Ann-Marie Mongan, Shivona Chetty, Darren M J McAteer, Shauna M Quinn
INTRODUCTION: To determine visual and anatomical outcomes of diabetic macular oedema (DMO) patients in a tertiary centre following conversion to aflibercept having been refractory to previous treatment with bevacizumab/ranibizumab. METHODS: A retrospective case series of patients with a diagnosis of DMO undergoing aflibercept intravitreal therapy for at least 6 months who had previous treatment with three consecutive bevacizumab/ranibizumab injections pre-switch...
March 5, 2018: Ophthalmology and Therapy
Nino Hirnschall, Ralph Varsits, Birgit Doeller, Oliver Findl
INTRODUCTION: The aim of this study was to find cases in which the axial eye length could not be measured with partial coherence interferometry (PCI) technology and to assess if it could be measured using swept source optical coherence tomography (ss-OCT) technology. METHODS: All patients were measured at their pre-assessment visit 1 week prior to cataract surgery using conventional optical biometry (PCI technology, IOLMaster 500, Carl Zeiss Meditec AG, Jena, Germany)...
March 1, 2018: Ophthalmology and Therapy
Ilaria Zucchiatti, Riccardo Sacconi, Maria Cristina Parravano, Eliana Costanzo, Lea Querques, Daniela Montorio, Francesco Bandello, Giuseppe Querques
INTRODUCTION: To investigate the effects of eplerenone compared to observation in the treatment of acute central serous chorioretinopathy (CSC). METHODS: Charts of consecutive patients with a diagnosis of acute CSC (visual symptoms < 12 weeks) were reviewed. Included patients were divided into a treatment group (treated with eplerenone) and a control group (observation). Main outcome measures included changes in best-corrected visual acuity (BCVA), central macular thickness (CMT), height of subretinal fluid (SRF) and subfoveal choroidal thickness (CT) at 1 and 3 months in the two groups...
February 13, 2018: Ophthalmology and Therapy
Adi M Al Owaifeer, Abdulaziz A Al Taisan
Intraocular pressure (IOP) reduction by medications, laser, or surgery remains the mainstay of treatment in glaucoma. However, the role of complementary and alternative medicine (CAM) in glaucoma has received great interest from both patients and ophthalmologists. Previous evidence suggests that diet, a major domain of CAM, can influence an individual's IOP level. Furthermore, certain dietary components have been linked to the incidence and progression of glaucoma. In this review, we aim to provide a summary of the current evidence regarding the role of obesity, certain dietary components, and dietary supplements in glaucoma...
February 8, 2018: Ophthalmology and Therapy
Irini Chatziralli, George Theodossiadis, Dimitrios Panagiotidis, Paraskevi Pousoulidi, Panagiotis Theodossiadis
INTRODUCTION: The purpose of this study was to investigate the extent and morphology of the choriocapillaris' density defect in patients with drusen in non-neovascular age-related macular degeneration (AMD). METHODS: Participants in this study were 36 patients with non-neovascular AMD and drusen. All patients underwent best-corrected visual acuity, slit-lamp examination, spectral domain-optical coherence tomography (SD-OCT), and optical coherence tomography angiography (OCTA)...
January 30, 2018: Ophthalmology and Therapy
Rahim Mahmodlou, Fahimeh Asadi Amoli, Ata Abbasi, Seyed Arman Seyed Mokhtari, Sajjad Pourasghary
In this report, a case of ocular scleral metastasis was reported in a patient with a past history of esophageal squamous cell carcinoma. The patient was a 58-year-old male who was admitted to Urmia Imam Khomeini Hospital, Urmia, Iran, 8 years ago with progressive dysphasia. Seven years after initial diagnosis and treatment of esophageal cancer, the patient had no signs or symptoms of the disease. But 2 months ago, he was referred to the hospital due to ocular swelling, redness and watering. Pathologic examination of the excised lesion at Farabi Hospital reported metastasis of squamous cell carcinoma to the connective tissue of the sclera...
January 5, 2018: Ophthalmology and Therapy
Zisis Gatzioufas, Aye Khine, Mohamed Elalfy, Ivo Guber, Cameron McLintock, Francesco Sabatino, Samer Hamada, Damian Lake
BACKGROUND: Intracorneal ring segment implantation is an effective and safe method of visual improvement in patients with keratoconus. The aim of our study was to evaluate the long-term clinical outcomes after Keraring implantation for keratoconus in patients older than 40 years. METHODS: Eleven eyes from 11 patients with keratoconus who underwent femtosecond laser-assisted Keraring implantation for keratoconus were included in this retrospective study. The uncorrected visual acuity (UCVA), corrected visual acuity, keratometric readings, central corneal thickness and thinnest corneal pachymetry were evaluated preoperatively and 6 months after the Keraring implantation...
December 23, 2017: Ophthalmology and Therapy
Gijsbert J Hötte, Daniël P de Bruyn, Joeri de Hoog
INTRODUCTION: Many authors have reported on a myopic post-operative refractive prediction error when combining phacoemulsification with pars plana vitrectomy (phacovitrectomy). In this study we evaluate the amount of this error in our facility and try to elucidate the various factors involved. METHODS: This was a retrospective study which included 140 patients who underwent phacovitrectomy (39 with macular holes, 88 with puckers, and 13 with floaters). Post-operative refractive error was defined as the difference between the actual spherical equivalent (SEQ) and expected SEQ based on the SRK/T and Holladay-II formulas...
December 13, 2017: Ophthalmology and Therapy
Cristina Nicula, Radu Nicolae Pop, Dorin V Nicula
INTRODUCTION: Corneal thinning disorders caused by keratoconus often lead to protrusion, irregular astigmatism, and even perforation. Keratoconus, like other corneal ectasia, does not have a known cause. Severe cases of keratoconus may require correction or restoration of tectonic integrity of the cornea by surgical means. Intracorneal ring segments are a new modality in the treatment of corneal ectactic disorders. A new technique of stopping the evolution of keratoconus and strengthening the cornea is combining techniques of intrastromal corneal ring implantation and corneal collagen cross-linking...
December 2017: Ophthalmology and Therapy
Christina Garnavou-Xirou, Tina Xirou, Stamatina Kabanarou, Ilias Gkizis, Stavros Velissaris, Irini Chatziralli
INTRODUCTION: Postoperative eccentric macular hole formation is an uncommon complication after pars plana vitrectomy (PPV) without internal limiting membrane (ILM) peeling for the treatment of epiretinal membrane (ERM). We present a case of eccentric macular hole formation after PPV for ERM without ILM peeling. CASE REPORT: A 68-year-old male patient presented with ERM and visual acuity of 6/24 in his left eye. He underwent 23-gauge PPV without ILM peeling for treatment of ERM...
December 2017: Ophthalmology and Therapy
Andrea Appeltans, Marco Mura, Giulio Bamonte
INTRODUCTION: The purpose of this report is to describe a case of macular hole development after vitrectomy for floaters with induction of posterior vitreous detachment. CASE REPORT: A 44-year-old otherwise healthy man presented with visually debilitating floaters in his right eye; these had been present for more than 2 years. Preoperative examination was unremarkable in both eyes, apart from some degree of vitreous degeneration in the right eye. Preoperative visual acuity was 20/20 bilaterally...
December 2017: Ophthalmology and Therapy
George W Ousler, David Rimmer, Lisa M Smith, Mark B Abelson
The many internal and external factors that contribute to the pathophysiology of dry eye disease (DED) create a difficult milieu for its study and complicate its clinical diagnosis and treatment. The controlled adverse environment (CAE® ) model has been developed to minimize the variability that arises from exogenous factors and to exacerbate the signs and symptoms of DED by stressing the ocular surface in a safe, standardized, controlled, and reproducible manner. By integrating sensitive, specific, and clinically relevant endpoints, the CAE has proven to be a unique and adaptable model for both identifying study-specific patient populations with modifiable signs and symptoms, and for tailoring the evaluation of interventions in clinical research studies...
December 2017: Ophthalmology and Therapy
Gennady Landa, Khoa Pham
INTRODUCTION: Primary posterior capsular plaques can be highly adherent to the posterior capsule leading to possible posterior capsular rupture during attempted removal. Here we describe a novel method for posterior capsular plaque removal using a technique inspired by the experience of retina surgeon in the peeling of membranes from the posterior pole. METHODS: Retinal end-grasping forceps were used to peel the plaque from the posterior capsule. RESULTS: We have performed this technique on 12 eyes with successful removal of the posterior capsular plaque in all instances without compromise of the posterior capsule in any case...
December 2017: Ophthalmology and Therapy
Mohamed Nagy Elmohamady, Walid Abdelghaffar
INTRODUCTION: The objective of this study was to evaluate the changes of the anterior chamber (AC) of the eye after implantable Collamer lens (ICL) implantation in high myopia by using the Pentacam. METHODS: The prospective study included 34 high myopic patients (34 eyes). All patients were treated with Visian implantable Collamer lens (ICL) (Staar Surgical Co.) implantation. The Pentacam (Oculus) was used for all cases preoperatively and 1, 3 and 6 months postoperatively...
December 2017: Ophthalmology and Therapy
Reiko Tanabu, Yukihiko Suzuki, Kaori Suzuki, Shizuka Takahashi, Mitsuru Nakazawa, Hideyuki Mizutani
INTRODUCTION: To prevent local reduction in retinal function caused by retained subretinal perfluorocarbon liquid (PFCL), it has been noted that removal of PFCL under the fovea should be considered, with a vitrectomy selected for such removal. CASE REPORT: A vitrectomy was performed for traumatic retinal detachment during which PFCL was temporarily used as an intraocular tamponade for retina flattening. Following surgery, subfoveal PFCL was retained beneath the retina...
December 2017: Ophthalmology and Therapy
Ejaz Ansari
No abstract text is available yet for this article.
December 2017: Ophthalmology and Therapy
Daren Hanumunthadu, Victoria A Nowak, Farida Hassan, Ibtesham Hossain, Darshak S Patel, Lamia Hamidovic, Dalia Abdulhussein, Isra Hausien, Esther Papamichael, Meena Arunakirinathan, Claudia Quijano, Sheena George, Praveen J Patel
INTRODUCTION: The aim of this study was to determine treatment delivery patterns for patients with neovascular age-related macular degeneration (nAMD) across the UK through an ophthalmology trainee research network delivered observational study. METHODS: Data were collected via an online tool by potential research collaborators identified by the Ophthalmology Trainee Clinical Trial Network (OCTN). Collaborators were asked to comment on periprocedural practices of treatment of nAMD in their eye unit including treatment location and injectors, clinical assessment and routine observation in patients undergoing intravitreal treatment...
December 2017: Ophthalmology and Therapy
Majid Moshirfar, Andrew E Bean, Jordan D Desautels, Orry C Birdsong
INTRODUCTION: This report describes the first known case of late-onset intrusion of an intrastromal ring segment into the anterior chamber due to posterior migration of a ring segment. To our knowledge, intrastromal ring segment penetration has only been shown to occur in the intraoperative or immediate postoperative period. We postulate that the perforation in this case is due to progressive thinning of the cornea, possibly in combination with habitual eye rubbing. CASE REPORT: A 44-year-old man presented with acute corneal hydrops related to penetration of Descemet's membrane and endothelium by an intrastromal ring segment implanted 7 years prior...
December 2017: Ophthalmology and Therapy
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