journal
MENU ▼
Read by QxMD icon Read
search

Pain and Therapy

journal
https://www.readbyqxmd.com/read/27900726/survey-on-german-palliative-care-specialists-experiences-with-advance-directives
#1
Julia Zenz, Michael Zenz
INTRODUCTION: Advance directives (AD) play a central role in end-of-life treatments, intensive care, and palliative care. However, little is known about the experiences of healthcare professionals with ADs. This study reports on palliative care professionals' views on advance directives (AD). METHODS: A questionnaire was handed out to attendants of a palliative care symposium. RESULTS: Complete answers were obtained from 126 physicians and 276 nurses...
November 29, 2016: Pain and Therapy
https://www.readbyqxmd.com/read/27873179/oxycodone-deterx-%C3%A2-a-novel-abuse-deterrent-extended-release-analgesic-option-for-the-treatment-of-patients-with-chronic-pain
#2
REVIEW
Jeff Gudin
BACKGROUND: Extended-release (ER) opioid analgesics are commonly used to provide safe and effective pain relief to treat pain severe enough to require around-the-clock, long-term dosing. These ER opioid formulations usually contain more drug per dosage unit than immediate-release (IR) agents, and therefore bring with them challenges related to both opioid abuse and misuse, often through manipulation of the dosage form. Oxycodone DETERx(®) (Xtampza(®) ER, Collegium Pharmaceutical, Inc...
December 2016: Pain and Therapy
https://www.readbyqxmd.com/read/27830531/treatment-of-severe-pain-and-opioid-induced-constipation-an-observational-study-of-quality-of-life-resource-use-and-costs-in-sweden
#3
Frida Hjalte, Gunnel Ragnarson Tennvall, Karl-Olof Welin, Dagmar Westerling
INTRODUCTION: Opioid-induced constipation (OIC) is a common and costly side effect of opioid treatment affecting patients' quality of life (QoL). The combination oxycodone/naloxone reduces OIC while providing effective analgesia in patients with moderate to severe pain. The objective of this observational study was to compare health-related quality of life (HRQoL), healthcare resource use, and costs in patients with severe pain who were initially treated with oxycodone and laxatives and then subsequently switched to treatment with oxycodone/naloxone...
December 2016: Pain and Therapy
https://www.readbyqxmd.com/read/27822619/the-5-lidocaine-medicated-plaster-its-inclusion-in-international-treatment-guidelines-for-treating-localized-neuropathic-pain-and-clinical-evidence-supporting-its-use
#4
REVIEW
Ralf Baron, Massimo Allegri, Gerardo Correa-Illanes, Guy Hans, Michael Serpell, Gerard Mick, Victor Mayoral
When peripheral neuropathic pain affects a specific, clearly demarcated area of the body, it may be described as localized neuropathic pain (LNP). Examples include postherpetic neuralgia and painful diabetic neuropathy, as well as post-surgical and post-traumatic pain. These conditions may respond to topical treatment, i.e., pharmaceutical agents acting locally on the peripheral nervous system, and the topical route offers advantages over systemic administration. Notably, only a small fraction of the dose reaches the systemic circulation, thereby reducing the risk of systemic adverse effects, drug-drug interactions and overdose...
December 2016: Pain and Therapy
https://www.readbyqxmd.com/read/27817153/use-of-fentanyl-iontophoretic-transdermal-system-its-ionsys-%C3%A2-in-the-management-of-patients-with-acute-postoperative-pain-a-case-series
#5
Steven Poplawski, Matthew Johnson, Philip Philips, Leopold H J Eberhart, Tilo Koch, Loretta M Itri
Fentanyl iontophoretic transdermal system (ITS) [IONSYS(®), The Medicines Company, Parsippany, NJ, USA] is a needle-free, patient-controlled, postoperative opioid pain management treatment. It is indicated for the short-term management of acute postoperative pain in adults requiring opioid analgesia in the hospital. The safety and effectiveness of fentanyl ITS for acute postoperative pain management has been demonstrated in a range of surgery and patient types studied in seven phase 3 trials (three placebo-controlled trials and four active-comparator trials)...
December 2016: Pain and Therapy
https://www.readbyqxmd.com/read/27743137/change-pain-ever-evolving-an-update-for-2016
#6
EDITORIAL
Joseph V Pergolizzi, Antonella Paladini, Giustino Varrassi, Robert B Raffa
Since 1986, the pharmacological management of pain was mainly based on the WHO "analgesic ladder", with very few drugs available. The huge development of the basic knowledge on pain and its therapy, especially in the past 15 years, has made the "guidelines" of WHO obsolete. That's why, during the presidency of EFIC of one of the authors (GV), an international advisory board was proposed to review the document, but mainly to ameliorate the approach to the pain patients.
December 2016: Pain and Therapy
https://www.readbyqxmd.com/read/27704485/health-care-utilization-and-costs-associated-with-nausea-and-vomiting-in-patients-receiving-oral-immediate-release-opioids-for-outpatient-acute-pain-management
#7
Elizabeth Marrett, Winghan Jacqueline Kwong, Feride Frech, Chunlin Qian
INTRODUCTION: Nausea and vomiting (NV) are common side effects of opioid use and limiting factors in pain management. This study sought to quantify the frequency of antiemetic prescribing and the impact of NV on health care resource utilization and costs in outpatients prescribed opioids for acute pain. The perspective was that of a commercial health plan. METHODS: Medical and pharmacy claims from IMS PharMetrics Plus were used to identify patients initiating opioid therapy with a prescription for an oxycodone-, hydrocodone- or codeine-containing immediate-release product for acute use (≤15-day supply) between October 1, 2013 and September 30, 2014...
December 2016: Pain and Therapy
https://www.readbyqxmd.com/read/27650441/the-cold-pressor-test-as-a-predictor-of-prolonged-postoperative-pain-a-prospective-cohort-study
#8
Cameron MacLachlan, Edward A Shipton, J Elisabeth Wells
INTRODUCTION: Presently, it is difficult to predict which patients are at increased risk of ongoing pain problems postoperatively. This study followed a group of patients from the week before their operation until 3 months after it, to identify potential risk variables. METHODS: Fifty-four patients undergoing moderate-major gynaecological surgery at Christchurch Women's Hospital were recruited and assessed preoperatively over an 11-week period. At this initial assessment, participants were subjected to a cold pressor test (CPT)...
December 2016: Pain and Therapy
https://www.readbyqxmd.com/read/27550176/practice-based-research-networks-integrating-clinical-data-for-improved-pharmacoepidemiology
#9
Tiago Sousa-Veloso
Pharmacovigilance is concerned with the detection, assessment, understanding, and prevention of adverse reactions to medicines. It is helpful to prevent undesired harm sustained by the patient due to inappropriate or unsafe use of medicinal agents. As the use of drugs and polypharmacy increase in prevalence, pharmacovigilance gains relevance and momentum. Practice-based research networks have the potential to enhance health research by promoting earlier detection of adverse events at a decreased level of cost...
December 2016: Pain and Therapy
https://www.readbyqxmd.com/read/27515841/encountering-a-neglected-area-of-a-healthcare-system-a-decade-of-improvement-in-cancer-pain-clinical-practice-in-iran
#10
Farid A Gharehdaghi, Mansoureh Gorginzadeh, Saeid Safari
BACKGROUND: With the increase in the prevalence of cancer, cancer-related issues also deserve more attention especially in developing countries where there is already limited access to high-quality healthcare. Cancer-related pain, the most common and the most annoying one, is not only a symptom but also an important subspecialty and its management is still challenging. OBJECTIVES: To assess the level of pain and cancer pain knowledge in Iran in comparison with the whole world...
December 2016: Pain and Therapy
https://www.readbyqxmd.com/read/27295264/how-resistant-to-tampering-are-codeine-containing-analgesics-on-the-market-assessing-the-potential-for-opioid-extraction
#11
Andreas Kimergård, Paolo Deluca, Peter Hindersson, Torben Breindahl
INTRODUCTION: Misuse of opioid analgesics, in combination with diversion, dependence, and fatal overdoses, presents a serious problem for public health, which affects many countries worldwide. Within this context, tampering with opioids has been associated with serious harm. The aim of the present study was to assess the tampering potential of codeine combination analgesics on the market (containing codeine/non-opioid analgesics) by the extraction of codeine. METHODS: Codeine was extracted from three combination formulations sold lawfully from licensed pharmacies without a medical prescription in Denmark and the UK...
December 2016: Pain and Therapy
https://www.readbyqxmd.com/read/27229350/should-the-general-practitioner-consider-mesotherapy-intradermal-therapy-to-manage-localized-pain
#12
Massimo Mammucari, Enrica Maggiori, Marzia Lazzari, Silvia Natoli
Wide variations in the types of pain and response to analgesic pharmacotherapy mean that a variety of treatment strategies are needed. One approach is mesotherapy (intradermal therapy). This consists of microinjections into the skin and is ideally suited to the management of localized pain. Advantages include increasing the duration of drug activity, reduced risk of adverse events and interactions, and possible synergy with other therapies. Mesotherapy provides general practitioners with another tool for the treatment of local pain...
June 2016: Pain and Therapy
https://www.readbyqxmd.com/read/27160684/oxycodone-and-naloxone-combination-a-12-week-follow-up-in-20-patients-shows-effective-analgesia-without-opioid-induced-bowel-dysfunction
#13
Gareth P Jones, Shiva S Tripathi
INTRODUCTION: Opioid analgesics are widely regarded to be highly effective but are equally known for their side effects on the bowel. A new combination of the opioid analgesic oxycodone and naloxone has been developed to combat opioid-induced bowel dysfunction (OIBD) whilst still being effective as an analgesic. The aim of this observational study was to assess the analgesic efficacy of this new combination and to analyze its effect on bowel function. METHODS: Twenty-six patients underwent a trial of this new combination, with 21 patients reaching week 8 and 18 reaching week 12...
June 2016: Pain and Therapy
https://www.readbyqxmd.com/read/27001634/ultrasound-guided-parasternal-block-allows-optimal-pain-relief-and-ventilation-improvement-after-a-sternal-fracture
#14
Kurian P Thomas, Shaji Sainudeen, Suraj Jose, Mansour Y Nadhari, Philippe B Macaire
INTRODUCTION: Sternal fractures are a painful condition which can result in pulmonary morbidity if not treated promptly. The management of isolated fractures has changed from hospital to home-based treatment, provided other major injuries have been excluded. Pain management is the mainstay of treatment. In this case report, we describe how a parasternal block under ultrasound guidance for sternal fracture provided better analgesia thereby improving ventilation. CASE REPORT: A 26-year-old man was admitted to the emergency department following a road traffic accident...
June 2016: Pain and Therapy
https://www.readbyqxmd.com/read/26984272/melatonin-in-chronic-pain-syndromes
#15
REVIEW
Andrei Danilov, Julia Kurganova
Melatonin is a neurohormone secreted by epiphysis and extrapineal structures. It performs several functions including chronobiotic, antioxidant, oncostatic, immune modulating, normothermal, and anxiolytic functions. Melatonin affects the cardiovascular system and gastrointestinal tract, participates in reproduction and metabolism, and body mass regulation. Moreover, recent studies have demonstrated melatonin efficacy in relation to pain syndromes. The present paper reviews the studies on melatonin use in fibromyalgia, headaches, irritable bowel syndrome, chronic back pain, and rheumatoid arthritis...
June 2016: Pain and Therapy
https://www.readbyqxmd.com/read/26935739/learning-to-manage-chronic-pain-the-patients-perspective
#16
Eleni G Hapidou, Emily Horst
INTRODUCTION: The objective of the present study was to gain insight into patients' experiences in a 4-week interdisciplinary chronic pain management program by determining major themes from patients' written comments on exit questionnaires. METHODS: Upon completion of the program at the Chronic Pain Management Unit (CPMU), patients fill out program satisfaction (Pain Program Satisfaction Questionnaire) and evaluation of goal accomplishment (Self-Evaluation Scale) forms, sections of which are open-ended...
June 2016: Pain and Therapy
https://www.readbyqxmd.com/read/26932262/the-cost-effectiveness-of-pregabalin-versus-gabapentin-for-peripheral-neuropathic-pain-pnep-and-postherpetic-neuralgia-phn-in-china
#17
Bruce C M Wang, Dongdong Liu, Wesley E Furnback, Fan Bifa, Peng Dong, Li Xie, Gregory F Guzauskas, Sali Zhang
INTRODUCTION: Postherpetic neuralgia (PHN), a type of peripheral neuropathic pain (pNeP), is the most common complication of herpes zoster. The objective of this analysis was to determine the cost-effectiveness of pregabalin compared with gabapentin in pNeP and PHN in China. METHODS: We developed a China-localized 12-week simulation model to determine the cost-effectiveness of pregabalin compared to gabapentin in 1000 patients with pNeP and PHN. We utilized a questionnaire of Chinese key opinion leaders to estimate the pre-treatment distribution of pain scores for pNeP and PHN...
June 2016: Pain and Therapy
https://www.readbyqxmd.com/read/26861737/efficacy-of-intraoperative-dexmedetomidine-compared-with-placebo-for-postoperative-pain-management-a-meta-analysis-of-published-studies
#18
Myriam Bellon, Alix Le Bot, Daphnée Michelet, Julie Hilly, Mathieu Maesani, Christopher Brasher, Souhayl Dahmani
INTRODUCTION: Dexmedetomidine (Dex) has sedative, analgesic, and anesthetic-sparing effects. This meta-analysis examines demonstrated intraoperative and postoperative effects of intraoperative Dex administration during pediatric surgery. METHODS: A search for randomized placebo-controlled trials was conducted to identify clinical trials examining intraoperative Dex use in children, infants, and neonates. Primary outcome was postoperative opioid consumption; secondary outcomes were: postoperative pain intensity and postoperative nausea and vomiting (PONV)...
June 2016: Pain and Therapy
https://www.readbyqxmd.com/read/26861666/parecoxib-possesses-anxiolytic-properties-in-patients-undergoing-total-knee-arthroplasty-a-prospective-randomized-double-blind-placebo-controlled-clinical-study
#19
Despoina G Sarridou, Georgia Chalmouki, Maria Braoudaki, Ioanna Siafaka, Chrisi Asmatzi, Athina Vadalouka
INTRODUCTION: Intravenous administration of parecoxib could provide significant pain relief in surgical operations that require additional forms of analgesia. However, very little is known about its effects on the anxiety levels of patients before a surgical procedure. The aim of this prospective study was to investigate whether intravenous parecoxib, pre-emptively administered, has an effect on anxiety levels experienced post-surgically after total knee arthroplasty (TKA) and if it influences the reported pain of the procedure itself...
June 2016: Pain and Therapy
https://www.readbyqxmd.com/read/26792136/the-ac-ag-diplotype-for-the-118a-g-and-ivs2%C3%A2-%C3%A2-691g-c-polymorphisms-of-oprm1-gene-is-associated-with-sleep-quality-among-opioid-dependent-patients-on-methadone-maintenance-therapy
#20
Zalina Zahari, Chee Siong Lee, Muslih Abdulkarim Ibrahim, Nurfadhlina Musa, Mohd Azhar Mohd Yasin, Yeong Yeh Lee, Soo Choon Tan, Nasir Mohamad, Rusli Ismail
INTRODUCTION: Methadone is a full agonist of the opioid receptor mu 1 which is encoded by the OPRM1 gene. Sleep disorders were frequently reported by opioid-dependent patients during methadone maintenance therapy (MMT). It is possible, therefore, that genetic polymorphisms in OPRM1 influence sleep quality among patients on MMT. This study investigated the association of OPRM1 polymorphisms with sleep quality among opioid-dependent patients on MMT. METHODS: The sleep quality of 165 male opioid-dependent patients receiving MMT was evaluated using the Pittsburgh Sleep Quality Index (PSQI)...
June 2016: Pain and Therapy
journal
journal
48934
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"