journal
MENU ▼
Read by QxMD icon Read
search

Movement Disorders Clinical Practice

journal
https://www.readbyqxmd.com/read/27774496/parkinson-s-impulse-control-scale-for-the-severity-rating-of-impulse-control-behaviors-in-parkinson-s-disease-a-semistructured-clinical-assessment-tool
#1
David Okai, Sally Askey-Jones, Joel Mack, Anne Martin, Kallol Ray Chaudhuri, Michael Samuel, Anthony S David, Richard G Brown
BACKGROUND: Impulse-control behaviors (ICBs) are increasingly recognized in Parkinson's disease (PD) as drug-related effects of dopaminergic mediation that occur in 15% to 35% of patients with PD. The authors describe the design and evaluation of a new, clinician-rated severity scale for the assessment of syndromal and subsyndromal forms of impulse-control disorders (ICDs), simple (punding) and complex (hobbyism) repetitive behaviors, and compulsive overuse of medication (dopamine dysregulation syndrome)...
September 2016: Movement Disorders Clinical Practice
https://www.readbyqxmd.com/read/27713907/utility-of-electronic-medical-record-for-recruitment-in-clinical-research-from-rare-to-common-disease
#2
Tapan Thacker, Ashley R Wegele, Sarah Pirio Richardson
BACKGROUND: Recruitment for clinical trials is a major challenge. Movement disorders, which do not have associated diagnostic laboratory tests, may be especially prone to inaccuracy in coding. Our objective was to evaluate the accuracy of diagnostic codes such as cervical dystonia (CD) and PD in an electronic medical record. METHODS: Retrospective chart review was performed to confirm the ICD-9 diagnoses of PD, CD and diabetes mellitus type 2 (DM-2), using published clinical diagnostic criteria (PD, CD) and hemoglobin A1c ≥ 6...
September 2016: Movement Disorders Clinical Practice
https://www.readbyqxmd.com/read/27709117/genetic-and-clinical-predictors-of-deep-brain-stimulation-in-young-onset-parkinson-s-disease
#3
Gian D Pal, Deborah Hall, Bichun Ouyang, Jessica Phelps, Roy Alcalay, Michael W Pauciulo, William C Nichols, Lorraine Clark, Helen Mejia-Santana, Lucia Blasucci, Christopher G Goetz, Cynthia Comella, Amy Colcher, Ziv Gan-Or, Guy A Rouleau, Karen Marder
OBJECTIVE: In a cohort of patients with young-onset Parkinson's disease (PD), the authors assessed (1) the prevalence of genetic mutations in those who enrolled in deep brain stimulation (DBS) programs compared with those who did not enroll DBS programs and (2) specific genetic and clinical predictors of DBS enrollment. METHODS: Subjects were participants from 3 sites (Columbia University, Rush University, and the University of Pennsylvania) in the Consortium on Risk for Early Onset Parkinson's Disease (CORE-PD) who had an age at onset < 51 years...
September 2016: Movement Disorders Clinical Practice
https://www.readbyqxmd.com/read/27617270/deep-brain-stimulation-battery-longevity-comparison-of-monopolar-versus-bipolar-stimulation-modes
#4
Leonardo Almeida, Pawan V Rawal, Benjamin Ditty, Bryan L Smelser, He Huang, Michael S Okun, Barton L Guthrie, Harrison C Walker
BACKGROUND: Deep brain stimulation is an effective treatment for movement disorders, but it is relatively complex, invasive, and costly. Little is known about whether stimulation mode alters pulse generator (battery) longevity in routine clinical care. OBJECTIVE: To compare battery longevity during monopolar versus bipolar stimulation in patients who underwent deep brain stimulation for movement disorders. METHODS: We evaluated 2,902 programming adjustments and calculated the average stimulator settings for 393 batteries in 200 unique patients with Parkinson's disease and essential tremor...
July 2016: Movement Disorders Clinical Practice
https://www.readbyqxmd.com/read/27617269/clinicopathological-correlates-in-a-prnp-p102l-mutation-carrier-with-rapidly-progressing-parkinsonism-dystonia
#5
Chizoba C Umeh, Piyush Kalakoti, Michael K Greenberg, Silvio Notari, Yvonne Cohen, Pierluigi Gambetti, Adrian L Oblak, Bernardino Ghetti, Zoltan Mari
Parkinsonism-dystonia is rare in carriers of PRNP P102L mutation. Severity and distribution of prion protein (PrP) deposition may influence the clinical presentation. We present such clinic-pathological correlation in a 56-year-old male with a PRNP P102L mutation associated with a phenotype characterized by rapidly progressing parkinsonism-dystonia. The patient was studied clinically (videotaped exams, brain MRIs); molecular genetically (gene sequence analysis); and neuropathologically (histology, immunohistochemistry) during his 7-month disease course...
July 2016: Movement Disorders Clinical Practice
https://www.readbyqxmd.com/read/27500181/amyloid-beta-positron-emission-tomography-imaging-of-alzheimer-s-pathology-in-parkinson-s-disease-dementia
#6
Rizwan S Akhtar, Sharon X Xie, Laura Brennan, Michael J Pontecorvo, Howard I Hurtig, John Q Trojanowski, Daniel Weintraub, Andrew D Siderowf
BACKGROUND: Neuronal loss and α-synuclein (α-syn) pathology are diagnostic of PD in the appropriate clinical context. However, some PD patients have co-morbid Alzheimer's disease (AD) pathology on autopsy, including amyloid-β (Aβ) plaques and neurofibrillary tangles. Florbetapir((18)F) is a PET ligand that detects Aβ pathology. We hypothesized that florbetapir((18)F) imaging could detect Aβ pathology in Parkinson disease dementia (PDD) patients prior to death. OBJECTIVE: To determine the utility of florbetapir((18)F) PET imaging in detecting Aβ pathology in patients with autopsy-confirmed PDD...
July 2016: Movement Disorders Clinical Practice
https://www.readbyqxmd.com/read/27430001/ultrasound-as-diagnostic-tool-for-diaphragmatic-myoclonus
#7
Vesper Fe Marie Llaneza Ramos, Elaine Considine, Barbara I Karp, Codrin Lungu, Katharine Alter, Mark Hallett
BACKGROUND: Diaphragmatic myoclonus is a rare disorder of repetitive diaphragmatic contractions, acknowledged to be a spectrum that includes psychogenic features. Electromyography has been the diagnostic tool most commonly used in the literature. METHODS: To test if we could perform a noninvasive technique to delineate the diaphragm as the source of abnormal movements and demonstrate distractibility and entrainability, we used B-mode ultrasound in a patient with diaphragmatic myoclonus...
May 2016: Movement Disorders Clinical Practice
https://www.readbyqxmd.com/read/27340683/drum-pd-the-use-of-a-drum-circle-to-improve-the-symptoms-and-signs-of-parkinson-s-disease-pd
#8
Alexander Pantelyat, Candace Syres, Suzanne Reichwein, Allison Willis
BACKGROUND: Physical therapy can improve motor function in patients with PD. Music performance may be used to improve motor skills by rhythmic entrainment. Drumming has long been a part of traditional healing rituals worldwide, and is increasingly being utilized as a therapeutic strategy. METHODS: This pilot controlled prospective cohort trial assessed feasibility and effects of twice-weekly group West African drum circle classes for 6 weeks on PD patients' quality of life, symptoms, motor findings, cognition, and mood...
May 2016: Movement Disorders Clinical Practice
https://www.readbyqxmd.com/read/27331078/associations-and-implications-of-low-health-literacy-in-parkinson-s-disease
#9
Jori E Fleisher, Krunal Shah, Whitney Fitts, Nabila A Dahodwala
BACKGROUND: Low health literacy (HL) indicates a limited ability to understand and use basic information to make appropriate healthcare decisions. While low HL is associated with higher morbidity, mortality, and healthcare costs in multiple chronic conditions, little is known about HL and its associations in Parkinson's disease (PD). METHODS: Cross-sectional study of non-demented adults with PD participating in the National Parkinson Foundation Parkinson's Outcomes Project at the University of Pennsylvania...
May 2016: Movement Disorders Clinical Practice
https://www.readbyqxmd.com/read/27774495/impact-of-cervical-dystonia-on-work-productivity-an-analysis-from-a-patient-registry
#10
Eric S Molho, Mark Stacy, Patrick Gillard, David Charles, Charles H Adler, Joseph Jankovic, Marc Schwartz, Mitchell F Brin
BACKGROUND: Cervical dystonia is thought to result in high disease burden, but limited information exists on its impact on employment and work productivity. We utilized data from the Cervical Dystonia Patient Registry for the Observation of OnabotulinumtoxinA Efficacy (ClinicalTrials.gov identifier: NCT00836017) to assess the impact of cervical dystonia on employment and work productivity and examine the effect of onabotulinumtoxinA treatments on work productivity. METHODS: Subjects completed a questionnaire on employment status and work productivity at baseline and final visit...
March 2016: Movement Disorders Clinical Practice
https://www.readbyqxmd.com/read/27110585/onabotulinumtoxina-and-abobotulinumtoxina-dose-conversion-a-systematic-literature-review
#11
Khashayar Dashtipour, Jack J Chen, Alberto J Espay, Zoltan Mari, William Ondo
OBJECTIVE: This systematic review was performed to elucidate dosing practices, dosing conversions, and related outcomes from randomized controlled trials that directly compared onabotulinumtoxinA (ONA) and abobotulinumtoxinA (ABO) at various dose conversion ratios for therapeutic use in movement disorders. METHODS: A systematic review of 3 medical literature databases (PubMed, the Cochrane Library, and EMBASE) was performed to identify relevant comparative clinical studies, systematic reviews, and meta-analyses published in the English language between January 1991 and January 2015...
March 2016: Movement Disorders Clinical Practice
https://www.readbyqxmd.com/read/27430000/more-time-with-tremor-the-experience-of-essential-tremor-versus-parkinson-s-disease-patients
#12
Elan D Louis
BACKGROUND: A broad range of tremors occur in patients with essential tremor and Parkinson's disease; despite this, there are virtually no published data that focus on the patient perspective. The aims were to (1) assess the subjective experience of tremor, comparing essential tremor and Parkinson's disease patients, and (2) assess the clinical correlates of that experience (i.e., what specific clinical characteristics were associated with more experienced tremor)? METHODS: 121 essential tremor and 100 Parkinson's disease cases enrolled in a cross-sectional, clinical-epidemiological study underwent a detailed clinical assessment, which included a series of standardized questionnaires and neurological examination...
January 2016: Movement Disorders Clinical Practice
https://www.readbyqxmd.com/read/26998505/outcome-measures-for-parkinson-s-disease-dementia-a-systematic-review
#13
Samantha K Holden, Wallace E Jones, Keith A Baker, Isabel M Boersma, Benzi M Kluger
BACKGROUND: Parkinson's disease dementia (PDD) is a major cause of morbidity and mortality in Parkinson's disease (PD), which severely affects patient functioning and quality of life and increases the risk for nursing home admission. Unfortunately, current treatment options for PDD are limited and have only marginal therapeutic effects. As novel treatments are developed, there will be a need to assess their efficacy in well-designed randomized controlled trials. However, there is no consensus on the optimal outcome measures for use in PDD clinical trials...
January 2016: Movement Disorders Clinical Practice
https://www.readbyqxmd.com/read/26889496/ocular-palatal-tremor-plus-dystonia-new-syndromic-association
#14
Aasef G Shaikh, Fatema F Ghasia, Mahlon R DeLong, H A Jinnah, Alan Freeman, Stewart A Factor
OBJECTIVE: Ocular palatal tremor typically develops after a breach in the Guillian-Mollaret triangle. We herein describe a variant of this syndrome in which dystonia is also present, hence called, here, ocular palatal tremor plus dystonia. METHODS: We assessed eye-head movements and dystonia in six patients with ocular palatal plus dystonia. RESULTS: Among six patients with ocular palatal tremor two had focal dystonia, three had multifocal dystonia, and one had generalized dystonia...
September 1, 2015: Movement Disorders Clinical Practice
https://www.readbyqxmd.com/read/26660076/development-of-clinical-dementia-rating-scale-cutoff-scores-for-patients-with-parkinson-s-disease
#15
Kathryn A Wyman-Chick, B J Scott
BACKGROUND: The purpose of this study was to explore validity of the Clinical Dementia Rating Scale in measuring cognitive impairment among individuals with Parkinson's disease. The scale was created for use in patients with Alzheimer's disease and, to date, there have been no published studies examining if this tool is appropriate for patients with Parkinson's disease. METHODS: The data were obtained from the National Alzheimer's Coordinating Center database and included 490 subjects diagnosed with Parkinson's disease, further categorized as having Parkinson's disease dementia (n= 151), mild cognitive impairment (n= 186), or normal cognition (n = 153) by a treating physician...
September 1, 2015: Movement Disorders Clinical Practice
https://www.readbyqxmd.com/read/27088112/development-of-the-comprehensive-cervical-dystonia-rating-scale-methodology
#16
Cynthia L Comella, Susan H Fox, Kailash P Bhatia, Joel S Perlmutter, Hyder A Jinnah, Mateusz Zurowski, William M McDonald, Laura Marsh, Ami R Rosen, Tracy Waliczek, Laura J Wright, Wendy R Galpern, Glenn T Stebbins
We present the methodology utilized for development and clinimetric testing of the Comprehensive Cervical Dystonia (CD) Rating scale, or CCDRS. The CCDRS includes a revision of the Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS-2), a newly developed psychiatric screening tool (TWSTRS-PSYCH), and the previously validated Cervical Dystonia Impact Profile (CDIP-58). For the revision of the TWSTRS, the original TWSTRS was examined by a committee of dystonia experts at a dystonia rating scales workshop organized by the Dystonia Medical Research Foundation...
June 2015: Movement Disorders Clinical Practice
https://www.readbyqxmd.com/read/25984553/intention-tremor-of-the-legs-in-essential-tremor-prevalence-and-clinical-correlates
#17
Meir Kestenbaum, Monika Michalec, Qiping Yu, Seth L Pullman, Elan D Louis
OBJECTIVE: To estimate the prevalence and assess the clinical correlates of intention tremor in the legs in essential tremor (ET) patients. BACKGROUND: The cerebellar features of ET are of growing interest to clinical neurologists. Arm tremor has an intentional component in many ET patients. Intention tremor in the legs, however, has never been systematically evaluated. METHODS: One-hundred-twenty-eight ET patients were enrolled in a clinical-epidemiological study at Columbia University...
March 1, 2015: Movement Disorders Clinical Practice
https://www.readbyqxmd.com/read/25961068/diagnostic-performance-of-the-huffing-and-puffing-sign-in-psychogenic-functional-movement-disorders
#18
Holly N Laub, Alok K Dwivedi, Fredy J Revilla, Andrew P Duker, Cara Pecina-Jacob, Alberto J Espay
OBJECTIVE: To determine the diagnostic value of effort-associated behaviors ("huffing and puffing" spectrum) in patients with psychogenic movement disorders. METHODS: Three blinded clinicians rated presence, severity, and duration of effort-associated features during standing and walking tasks on edited videos of 131 patients with psychogenic gait disorders and 37 patients with organic gait disorders. RESULTS: Huffing, grunting, grimacing, and breath holding were the most common effort-associated behaviors in patients with psychogenic gait disorders, with a combined prevalence of 44% and disproportionate to the severity of gait impairment compared to organic gait disorders...
March 1, 2015: Movement Disorders Clinical Practice
https://www.readbyqxmd.com/read/27066521/clinical-response-to-incobotulinumtoxina-after-demonstrated-loss-of-clinical-response-to-onabotulinumtoxina-and-rimabotulininumtoxinb-in-a-patient-with-musician-s-dystonia
#19
Vesper Fe Marie Llaneza Ramos, Barbara I Karp, Codrin Lungu, Katharine Alter, Mark Hallett
Botulinum toxin is a mainstay therapy for dystonia. Formulations available are three types of botulinumtoxinA and one type of botulinumtoxinB.(1) Antibodies can develop against the toxin, leading to treatment failure. IncobotulinumtoxinA (Xeomin; Merz Pharmaceuticals GmbH, Frankfurt, Germany) is differentiated from other types of botulinumtoxinA preparations by being free from complexing proteins, speculated to make the product less antigenic.(2).
December 2014: Movement Disorders Clinical Practice
https://www.readbyqxmd.com/read/25590046/head-accelerometry-may-be-useful-as-a-test-of-psychogenic-head-tremor
#20
Vesper Fe Marie Llaneza Ramos, Mark Hallett
No abstract text is available yet for this article.
December 2014: Movement Disorders Clinical Practice
journal
journal
48881
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"