Oluwatobi T Somade, Babajide O Ajayi, Olubisi E Adeyi, Temitope A Dada, Mukodaz A Ayofe, David C Inalu, Opeyemi I Ajiboye, Olaoluwawunmi M Shonoiki, Aminat O Adelabu, Rasaq T Onikola, Ismaila D Isiaka, Opeyemi Omotoso, Adewale S James, Tunde O Olaniyan, Ayodeji M Adegoke, Adio J Akamo, Babatunji E Oyinloye, Ezekiel Adewole
Hepatocellular carcinoma is a prevalent form of liver cancer that is life threatening. Many chemically synthesized anti-cancer drugs have various degrees of side effects. Hence, this study investigated the effect of FEAC interventions on NDEA-CCl4 -induced HCAR in male Wistar rats. HCAR was induced by intraperitoneal administration of 200 mg/kg of NDEA and 0.5 mL/kg CCl4 (as a promoter of HCAR). Following the induction of HCAR, rats were treated differently with two different doses (25 and 50 mg/kg) of FEAC...
June 2024: Toxicology Reports