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Current Treatment Options in Psychiatry

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https://www.readbyqxmd.com/read/30397577/mobile-app-tools-for-identifying-and-managing-mental-health-disorders-in-primary-care
#1
Joshua C Magee, Sarah Adut, Kevin Brazill, Stephen Warnick
Purpose of Review: Mental health apps are intriguing yet challenging tools for addressing barriers to treatment in primary care. In the current review, we seek to assist primary care professionals with evaluating and integrating mental health apps into practice. We briefly summarize two leading frameworks for evaluating mental health apps and conduct a systematic review of mental health apps across a variety of areas commonly encountered in primary care. Recent Findings: Existing frameworks can guide professionals and patients through the process of identifying apps and evaluating dimensions such as privacy and security, credibility, and user experience...
September 2018: Current Treatment Options in Psychiatry
https://www.readbyqxmd.com/read/30083495/financing-for-collaborative-care-a-narrative-review
#2
Andrew D Carlo, Jürgen Unützer, Anna D H Ratzliff, Joseph M Cerimele
Purpose of Review: Collaborative care (CoCM) is an evidence-based model for the treatment of common mental health conditions in the primary care setting. Its workflow encourages systematic communication among clinicians outside of face-to-face patient encounters, which has posed financial challenges in traditional fee-for-service reimbursement environments. Recent Findings: Organizations have employed various financing strategies to promote CoCM sustainability, including external grants, alternate payment model contracts with specific payers and the use of billing codes for individual components of CoCM...
September 2018: Current Treatment Options in Psychiatry
https://www.readbyqxmd.com/read/30364516/identifying-and-treating-the-prodromal-phases-of-bipolar-disorder-and-schizophrenia
#3
Susan Conroy, Michael Francis, Leslie A Hulvershorn
Purpose of review: The goal of this paper is to review recent research on the identification and treatment of prodromal periods that precede bipolar and psychotic disorders. We also sought to provide information about current best clinical practices for prodromal youth. Recent findings: Research in the areas of identifying prodromal periods has rapidly advanced. Calculators that can predict risk are now available for use during both bipolar and psychotic disorder prodromes...
March 2018: Current Treatment Options in Psychiatry
https://www.readbyqxmd.com/read/30319935/psychosocial-treatment-of-irritability-in-youth
#4
Katharina Kircanski, Michal E Clayton, Ellen Leibenluft, Melissa A Brotman
Purpose of review: Chronic, severe irritability is a common presenting problem in children and adolescents. Disruptive mood dysregulation disorder (DMDD) was added to the DSM-5 in recognition of this public health need. Currently there are no well-established, evidence-based pharmacological or psychosocial treatments specifically for DMDD. Here, we focus on psychosocial interventions. In addition to reviewing published research, we present preliminary, open trial data on a novel exposure-based cognitive-behavioral therapy (CBT) targeting severe irritability, as is present in DMDD...
March 2018: Current Treatment Options in Psychiatry
https://www.readbyqxmd.com/read/30237966/symptom-dimensions-in-obsessive-compulsive-disorder-as-predictors-of-neurobiology-and-treatment-response
#5
Anders Lillevik Thorsen, Gerd Kvale, Bjarne Hansen, Odile A van den Heuvel
Purpose of review: Specific symptom dimensions of obsessive-compulsive disorder (OCD) have been suggested as an approach to reduce the heterogeneity of obsessive-compulsive disorder, predict treatment outcome, and relate to brain structure and function. Here, we review studies addressing these issues. Recent findings: The contamination and symmetry/ordering dimensions have not been reliably associated with treatment outcome. Some studies found that greater severity of sexual/aggressive/religious symptoms predicted a worse outcome after cognitive behavioral therapy (CBT) and a better outcome after serotonin reuptake inhibitors (SRIs)...
March 2018: Current Treatment Options in Psychiatry
https://www.readbyqxmd.com/read/29755923/epigenetic-alterations-impact-on-antipsychotic-treatment-in-elderly-patients
#6
Bryan M McClarty, Daniel W Fisher, Hongxin Dong
Purpose of the review: Antipsychotics are commonly prescribed for the treatment of psychosis as well as behavioral and psychological symptoms of dementia (BPSD) in elderly patients. However, elderly patients often experience decreased antipsychotic efficacy and increased side effects, though the mechanisms underlying these changes with age are not clear. Recent findings: Although aging can affect drug metabolism and clearance through changes in renal and hepatic function, additional pharmacokinetic and pharmacodynamic changes due to aging-induced epigenetic alterations also impact processes important for antipsychotic function...
March 2018: Current Treatment Options in Psychiatry
https://www.readbyqxmd.com/read/29503793/treatment-of-psychiatric-symptoms-among-offspring-of-parents-with-bipolar-disorder
#7
Isheeta Zalpuri, Manpreet K Singh
Purpose of Review: Bipolar disorder is highly familial and has a protracted and diagnostically confusing prodrome. This review critically evaluates recently published literature relevant to the treatment of psychiatric symptoms in high-risk offspring of parents with Bipolar Disorder. Recent Findings: Non-pharmacological treatment options including psychotherapy, resilience promotion through good sleep, diet, and exercise hygiene, and omega-3 fatty acid supplementation are important first line interventions for high-risk offspring...
December 2017: Current Treatment Options in Psychiatry
https://www.readbyqxmd.com/read/29038777/the-abcd-study-of-neurodevelopment-identifying-neurocircuit-targets-for-prevention-and-treatment-of-adolescent-substance-abuse
#8
James M Bjork, Lisa K Straub, Rosellen G Provost, Michael C Neale
Substance use disorders (SUD) can be considered developmental disorders in light of their frequent origins in substance initiation during adolescence. Cross-sectional functional magnetic resonance imaging (fMRI) studies of adolescent substance users or adolescents with SUD have indicated aberrations in brain structures or circuits implicated in motivation, self-control, and mood-regulation. However, attributing these differences to the neurotoxicological effects of chronic substance use has been problematic in that these circuits are also aberrant in at-risk children, such as those with prenatal substance exposure, externalizing disorders (such as conduct disorder), or prodromal internalizing disorders such as depression...
June 2017: Current Treatment Options in Psychiatry
https://www.readbyqxmd.com/read/29034144/exercise-treatments-for-psychosis-a-review
#9
Vijay A Mittal, Teresa Vargas, K Juston Osborne, Derek Dean, Tina Gupta, Ivanka Ristanovic, Christine I Hooker, Stewart A Shankman
Schizophrenia is a devastating mental illness that has profound effects on a person's health and quality of life. Exercise represents a promising new treatment option that may supplement current psychosocial and pharmacological interventions for psychosis. A large body of work suggests that exercise can improve cardio-metabolic and health behavior and facilitate neurogenesis in areas of the brain that are notably impacted by psychosis. Recent efforts to incorporate exercise as either stand-alone or adjunctive treatment for individuals with schizophrenia range from yoga and light stretching to moderately intense walking, bike riding, or team sports...
June 2017: Current Treatment Options in Psychiatry
https://www.readbyqxmd.com/read/28674674/targeting-the-immune-system-with-pharmacotherapy-in-schizophrenia
#10
Jennifer K Melbourne, Benjamin Feiner, Cherise Rosen, Rajiv P Sharma
No abstract text is available yet for this article.
June 2017: Current Treatment Options in Psychiatry
https://www.readbyqxmd.com/read/28948135/pharmacological-management-of-anxiety-disorders-in-the-elderly
#11
Elizabeth A Crocco, Sindy Jaramillo, Caroline Cruz-Ortiz, Katherine Camfield
Anxiety disorders are common in the elderly. Additionally, anxiety symptoms often accompany co-morbid psychiatric, medical, as well as neurodegenerative diseases in the older population. Anxiety in the elderly, often accompanied by depression, can lead to worsening physical, cognitive and functional impairments in this vulnerable population. Antidepressants are considered first line treatment. Both SSRIs and SNRIs are efficacious and well-tolerated in the elderly. Some SSRIs are strong inhibitors of the cytochrome P450 hepatic pathway whereas others have less potential for drug interaction...
March 2017: Current Treatment Options in Psychiatry
https://www.readbyqxmd.com/read/28932652/psychosocial-treatment-options-for-major-depressive-disorder-in-older-adults
#12
Brenna N Renn, Patricia A Areán
Late-life depression (LLD) is a public health concern with deleterious effects on overall health, cognition, quality of life, and mortality. Although LLD is relatively common, it is not a normal part of aging and is often under-recognized in older adults. However, psychotherapy is an effective treatment for LLD that aligns with many patients' preferences and can improve health and functioning. This review synthesized the current literature on evidence-based psychotherapies for the treatment of depression in older adults...
March 2017: Current Treatment Options in Psychiatry
https://www.readbyqxmd.com/read/29238651/management-of-treatment-resistant-panic-disorder
#13
REVIEW
Giampaolo Perna, Daniela Caldirola
Purpose of Review: Purpose of Review Management of treatment-resistant (TR) panic disorder (PD) is an unresolved issue. In this paper, we provide a brief summary of previous findings, an updated (2015-2017) systematic review of pharmacological/non-pharmacological studies, and our personal perspective on this topic. Recent Findings: Recent Findings We found a very limited number of recent findings. Quetiapine extended-release augmentation has not been found to be beneficial, in comparison to placebo, in non-responders to previously recommended pharmacotherapy...
2017: Current Treatment Options in Psychiatry
https://www.readbyqxmd.com/read/28580231/hormones-and-neuropeptide-receptor-heteromers-in-the-ventral-tegmental-area-targets-for-the-treatment-of-loss-of-control-of-food-intake-and-substance-use-disorders
#14
REVIEW
Sergi Ferré
Hormones and neuropeptides represent biological correlates of internal homeostatic signals detected and integrated in the hypothalamus, which establishes a robust functional connection with the ventral tegmental area (VTA). The hypothalamus-VTA connection determines the ability of these signals to influence central dopaminergic neurotransmission and, therefore, their ability to increase responsiveness to their reward-associated stimuli and to establish appropriate associative learning. The hypothalamus also provides the main source of the multiple neuropeptides that are released in the VTA...
2017: Current Treatment Options in Psychiatry
https://www.readbyqxmd.com/read/28580230/the-use-of-long-acting-injectable-antipsychotics-in-schizophrenia
#15
REVIEW
Seiya Miyamoto, W Wolfgang Fleischhacker
Schizophrenia is a mostly chronic mental disorder, and symptomatic relapse is frequently observed. It is often associated with social and/or occupational decline that can be difficult to reverse. Most patients with the illness need long-term pharmacological treatment, and antipsychotic drugs represent the mainstay of clinical care. Long-acting injectable antipsychotics (LAIs) are an important alternative to oral medication, particularly advantageous in the context of compliance management. Several new-generation antipsychotics (NGAs), including risperidone, olanzapine, paliperidone, and aripiprazole, have become available as long-acting formulations, and new evidence has been accumulating...
2017: Current Treatment Options in Psychiatry
https://www.readbyqxmd.com/read/28018836/novel-therapeutics-for-addiction-behavioral-and-neuroeconomic-approaches
#16
Warren K Bickel, Alexandra M Mellis, Sarah E Snider, Lara Moody, Jeffrey S Stein, Amanda J Quisenberry
The maturing fields of behavioral- and neuro-economics provides conceptual understanding of the Competing Neurobehavioral Decision Systems theory (CNDS) and reinforcer pathology (i.e. high valuation of and excessive preference for drug reinforcers) allowing us to coherently categorize treatments into a theoretically comprehensive framework of addiction. In this chapter, we identify and clarify how existing and novel interventions can ameliorate reinforcer pathology in light of the CNDS and be leveraged to treat addiction...
September 2016: Current Treatment Options in Psychiatry
https://www.readbyqxmd.com/read/27493878/opioid-use-in-the-twenty-first-century-similarities-and-differences-across-national-borders
#17
Georgi Vasilev, Svetla Milcheva, Jasmin Vassileva
The global prevalence in the use of opiates and opioids has remained stable, though there were some unprecedented recent increases in opioid use and associated mortality and morbidity in the United States. Internationally, there is a strong tendency for consolidation of drug treatment strategies in favor of more systematic, structured and balanced approaches to regional and national drug policies. However, there are considerable differences in the scope, focus, and implementation of national drug policies and the political context is shaping drug prevention, treatment and rehabilitation efforts to an extent not typically observed in other public health domains...
September 2016: Current Treatment Options in Psychiatry
https://www.readbyqxmd.com/read/27648401/pharmacologic-treatment-of-pediatric-anxiety-disorders
#18
Farah S Hussain, Eric T Dobson, Jeffrey R Strawn
The last decade has seen considerable advances in the treatment of anxiety disorders in children and adolescents and a considerable expansion of the evidence base for psychopharmacologic in this population. The extant data suggest that, for fear-based anxiety disorders ( e.g. , generalized anxiety disorder, social phobia/social anxiety disorder, and separation anxiety disorder), selective serotonin reuptake inhibitors (SSRIs) and selective serotonin norepinephrine reuptake inhibitors (SSNRIs) are well tolerated and offer considerable benefit...
June 2016: Current Treatment Options in Psychiatry
https://www.readbyqxmd.com/read/27867834/neurobiology-of-risk-for-bipolar-disorder
#19
REVIEW
Ayşegül Özerdem, Deniz Ceylan, Güneş Can
Bipolar disorder (BD) is a chronic mental illness which follows a relapsing and remitting course and requires lifetime treatment. The lack of biological markers for BD is a major difficulty in clinical practice. Exploring multiple endophenotypes to fit in multivariate genetic models for BD is an important element in the process of finding tools to facilitate early diagnosis, early intervention, prevention of new episodes, and follow-up of treatment response in BD. Reviewing of studies on neuroimaging, neurocognition, and biochemical parameters in populations with high genetic risk for the illness can yield an integrative perspective on the neurobiology of risk for BD...
2016: Current Treatment Options in Psychiatry
https://www.readbyqxmd.com/read/27376016/treating-negative-symptoms-in-schizophrenia-an-update
#20
REVIEW
Gary Remington, George Foussias, Gagan Fervaha, Ofer Agid, Hiroyoshi Takeuchi, Jimmy Lee, Margaret Hahn
Interest in the negative symptoms of schizophrenia has increased rapidly over the last several decades, paralleling a growing interest in functional, in addition to clinical, recovery, and evidence underscoring the importance negative symptoms play in the former. Efforts continue to better define and measure negative symptoms, distinguish their impact from that of other symptom domains, and establish effective treatments as well as trials to assess these. Multiple interventions have been the subject of investigation, to date, including numerous pharmacological strategies, brain stimulation, and non-somatic approaches...
2016: Current Treatment Options in Psychiatry
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