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https://www.readbyqxmd.com/read/30202534/use-of-intravenous-immunoglobulin-for-the-treatment-of-autoimmune-encephalitis-audit-of-the-nhs-experience
#1
J A Kinsella, S R Irani, R Hollingsworth, D O'Shaughnessy, P Kane, M Foster, J M Schott, M P Lunn
Objectives: The treatments of limbic and other autoimmune encephalitis include immunosuppression, symptomatic treatment, and in the case of paraneoplastic syndromes, appropriate therapy for underlying neoplasms. When immunotherapy is considered, intravenous immunoglobulin is one option for treatment, either alone or in combination with corticosteroids. To date, however, evidence for the use of intravenous immunoglobulin in this context comes from case series/expert reviews as no controlled trials have been performed...
September 2018: JRSM Open
https://www.readbyqxmd.com/read/30202533/knowledge-attitude-perception-and-practice-regarding-antimicrobial-use-in-upper-respiratory-tract-infections-in-qatar-a-systematic-review
#2
REVIEW
F Shaikhan, S Rawaf, A Majeed, S Hassounah
Objective: To explore the knowledge, attitude, perception and practice towards antimicrobial use in upper respiratory tract infections in patients visiting healthcare settings in Qatar. Design: Systematic review was performed using a predetermined protocol and in accordance with standardized reporting guidelines. MEDLINE, PubMed, EMBASE, Global Health and PsycINFO were searched for relevant published studies using relevant MESH terms and keywords. Setting: All healthcare settings in Qatar including both inpatient and ambulatory care...
September 2018: JRSM Open
https://www.readbyqxmd.com/read/30181891/career-choices-for-nephrology-and-factors-influencing-them-surveys-of-uk-medical-graduates
#3
Atena Barat, Michael J Goldacre, Trevor W Lambert
Objectives: To study early and eventual career choices for nephrology among UK medical graduates and investigate factors which influenced career preferences. Design: Self-completed survey questionnaires mailed to medical graduates 1, 3, 5 and 10 years after graduation. Setting: United Kingdom. Participants: UK medical graduates in 15 year-of-qualification cohorts between 1974 and 2015. Main outcome measures: Early career specialty choices, career specialty destinations at 10 years and ratings of factors affecting career choices...
August 2018: JRSM Open
https://www.readbyqxmd.com/read/30094048/women-s-experiences-of-managing-digitation-do-we-ask-enough-in-primary-care
#4
Sharon Eustice, Ruth Endacott, Jenny Morris, Rohit Shankar, Bridie Kent
The aim of this paper was to consider the available evidence for the current management of pelvic organ prolapse, which is a common presentation in primary care. However, not all women will present, only presenting when symptoms become bothersome. Particular attention was paid to understanding the problem of rectocele and its influence on obstructive defaecation symptoms. The burden of rectocele and its consequences are not truly known. Furthermore, healthcare professionals may not always enquire about bowel symptoms and patients may not disclose them...
August 2018: JRSM Open
https://www.readbyqxmd.com/read/30013791/hba1c-and-hypoglycaemia-in-intensively-treated-type-2-diabetes-a-retrospective-cohort-study-in-primary-care
#5
Manil Malawana, Sally Kerry, Rohini Mathur, John Robson
Objective: To establish whether low HbA1c is associated with clinical hypoglycaemia among people with type 2 diabetes prescribed insulins or sulphonylureas. Design: Retrospective cohort study using routine electronic GP health records collected between January 2013 and December 2015. Setting: Three east London Clinical Commissioning Groups. Participants: Two cohorts of adults with type 2 diabetes prescribed either (i) insulins with or without other oral antidiabetic medication (nā€‰=ā€‰6788, 36...
July 2018: JRSM Open
https://www.readbyqxmd.com/read/29942535/iga-nephropathy-in-african-americans-uncommon-but-possible
#6
Abhilash Koratala, William L Clapp, Don H Esprit, Jogiraju Tantravahi
Though IgA nephropathy is relatively uncommon in African Americans, our case serves as a reminder that it needs to be considered in the differentials when these patients present with proliferative glomerulonephritis.
June 2018: JRSM Open
https://www.readbyqxmd.com/read/29942534/erratum
#7
(no author information available yet)
[This corrects the article DOI: 10.1177/2054270417751866.].
June 2018: JRSM Open
https://www.readbyqxmd.com/read/29770226/massive-haemorrhagic-blister-formation-following-total-knee-arthroplasty
#8
Aadhar Sharma, Padmanabhan Subramanian, Sunil Shah, Mohan Remani, Muhammad Shahid
Skin blistering following trauma is not uncommon; however, large haemorrhagic bullous blisters following total knee arthroplasty is relatively rare and not widely documented in the literature.
May 2018: JRSM Open
https://www.readbyqxmd.com/read/29760935/intestinal-obstruction-caused-by-desmoid-tumours-a-review-of-the-literature
#9
Amani Jambhekar, Shawn Robinson, Parvin Zafarani, James Rucinski, Prasad Gudavalli
Intraabdominal desmoid tumours are rare and can cause intestinal obstruction. Based on the review of the literature, surgical resection with negative margins and adjuvant chemotherapy is the optimal strategy for treatment of this pathology.
May 2018: JRSM Open
https://www.readbyqxmd.com/read/29707226/a-rare-case-of-retroperitoneal-synovial-sarcoma
#10
C S Wong, A Harris, R Kennedy, O P Houghton, P D Carey
Management of retroperitoneal soft tissue sarcomas is complex. Treatment is usually multimodal; involving surgery, chemotherapy and radiotherapy.
April 2018: JRSM Open
https://www.readbyqxmd.com/read/29707225/a-quantitative-analysis-of-antipsychotic-prescribing-trends-for-the-treatment-of-schizophrenia-in-england-and-wales
#11
Rossela Roberts, Abigail Neasham, Chania Lambrinudi, Afshan Khan
Objective: This study aims to assess the current antipsychotic prescribing trends for the treatment of schizophrenia and to compare them with available guidelines and research evidence. Design: An observational retrospective quantitative analysis. Setting: Data were collected from the prescribing cost analysis for the period between 2007 and 2014, including all drugs from the British National Formulary 4.2.1 and 4.2.2. Prescriptions were included from primary and secondary healthcare settings in England and Wales...
April 2018: JRSM Open
https://www.readbyqxmd.com/read/29707224/spontaneous-rupture-of-a-renal-artery-pseudoaneurysm-with-no-precipitating-risk-factor
#12
Marios Hadjipavlou, Jayasimha Abbaraju, Viktor Serafimov, Sanjeev Madaan
Renal artery pseudoaneurysm is a rare complication following renal interventional procedures or, although it may be spontaneous as described in this case. Clinicians should have a low threshold for early computer tomography (CT) imaging in cases of diagnostic uncertainty.
April 2018: JRSM Open
https://www.readbyqxmd.com/read/29552347/journalists-covering-the-refugee-and-migration-crisis-are-affected-by-moral-injury-not-ptsd
#13
Anthony Feinstein, Bennis Pavisian, Hannah Storm
Objective: To explore the emotional health of journalists covering the migrations of refugees across Europe. Design: Descriptive. A secure website was established and participants were given their unique identifying number and password to access the site. Setting: Newsrooms and in the field. Participants: Responses were received from 80 (70.2%) of 114 journalists from nine news organisations. Main outcome measures: Symptoms of PTSD (Impact of Events Scale-revised), depression (Beck Depression Inventory-Revised) and moral injury (Moral Injury Events Scale-revised)...
March 2018: JRSM Open
https://www.readbyqxmd.com/read/29552346/regional-differences-in-the-mid-victorian-diet-and-their-impact-on-health
#14
REVIEW
Peter Greaves
The aim of this study was to examine the impact of regional diets on the health of the poor in mid-Victorian Britain. Contemporary surveys of regional diets and living condition were reviewed. This information was compared with mortality data from Britain over the same period. Although there was an overall improvement in life expectancy during the latter part of the 19th century, there were large regional differences in lifestyle, diet and mortality rates. Dietary surveys showed that the poor labouring population in isolated rural areas of England, in the mainland and islands of Scotland and in the west of Ireland enjoyed the most nutritious diets...
March 2018: JRSM Open
https://www.readbyqxmd.com/read/29552345/cystitis-cystica-and-glandularis-producing-large-bladder-masses-in-a-16-year-old-boy
#15
Christopher Bastianpillai, Ross Warner, Luis Beltran, James Green
The macroscopic appearances of florid cystitis cystica et glandularis can be mistaken for malignancy, and it is therefore important to perform a prompt resection to confirm the histological diagnosis and exclude sinister pathology.
March 2018: JRSM Open
https://www.readbyqxmd.com/read/29552344/subpubic-cartilaginous-cyst-an-unusual-cause-of-urinary-tract-infection
#16
G Price, T McNicholas, S Buckingham, S Chang
It is important to consider alternative causes when treating refractory cases of urinary tract infection in the elderly population.
March 2018: JRSM Open
https://www.readbyqxmd.com/read/29487745/a-qualitative-study-of-the-perspectives-of-key-stakeholders-on-the-delivery-of-clinical-academic-training-in-the-east-midlands
#17
Ruth H Green, Val Evans, Sheona MacLeod, Jonathan Barratt
Objective: Major changes in the design and delivery of clinical academic training in the United Kingdom have occurred yet there has been little exploration of the perceptions of integrated clinic academic trainees or educators. We obtained the views of a range of key stakeholders involved in clinical academic training in the East Midlands. Design: A qualitative study with inductive iterative thematic content analysis of findings from trainee surveys and facilitated focus groups...
February 2018: JRSM Open
https://www.readbyqxmd.com/read/29487744/combined-caesarean-section-and-open-reduction-internal-fixation-for-the-treatment-of-an-acetabular-fracture-in-late-pregnancy
#18
Aimee Marie Charnell, Emma Ferriman, Rozalia Dimitriou, Michalis Panteli, Peter V Giannoudis
In this case, we opted for dual surgery combining caesarean section and internal fixation of acetabular fracture in late pregnancy, which allowed safe foetal delivery, fracture repair and early ambulation of the mother. In similar cases, this method could be potentially considered in the armamentarium of treatment options, aiming to facilitating prompt motherhood input and early hospital discharge, as well as minimising the risk of post-traumatic arthritis of the hip.
February 2018: JRSM Open
https://www.readbyqxmd.com/read/29487743/mullerian-duct-cyst-treated-with-template-guided-transperineal-aspiration-a-case-report-and-review-of-the-literature
#19
Carnjini Yogeswaran, Vaikuntam Srinivasan, Kingsley C Ekwueme
Template-guided transperineal aspiration is a minimally invasive treatment option for patients with Mullerian duct cysts. The precise targeting provided by the brachytherapy template grid enables specific targeting, quick recovery and resolution of symptoms without complications.
February 2018: JRSM Open
https://www.readbyqxmd.com/read/29344404/unleashing-the-tiger-iatrogenic-autoimmunity-from-cancer-immunotherapy-drugs
#20
Queenie Luu, Gabor Major
Immune checkpoint inhibitors can lead to the development of organ and non-organ specific immune related adverse events.
January 2018: JRSM Open
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