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IEEE Journal of Translational Engineering in Health and Medicine

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https://www.readbyqxmd.com/read/28560120/efficacy-evaluation-of-save-for-the-diagnosis-of-superficial-neoplastic-lesion
#1
Farah Deeba, Shahed K Mohammed, Francis Minhthang Bui, Khan A Wahid
The detection of non-polypoid superficial neoplastic lesions using current standard of white light endoscopy surveillance and random biopsy is associated with high miss rate. The subtle changes in mucosa caused by the flat and depressed neoplasms often go undetected and do not qualify for further investigation, e.g., biopsy and resection, thus increasing the risk of cancer advancement. This paper presents a screening tool named the saliency-aided visual enhancement (SAVE) method, with an objective of highlighting abnormalities in endoscopic images to detect early lesions...
2017: IEEE Journal of Translational Engineering in Health and Medicine
https://www.readbyqxmd.com/read/28512610/melanoma-is-skin-deep-a-3d-reconstruction-technique-for-computerized-dermoscopic-skin-lesion-classification
#2
T Y Satheesha, D Satyanarayana, M N Giri Prasad, Kashyap D Dhruve
Melanoma mortality rates are the highest amongst skin cancer patients. Melanoma is life threating when it grows beyond the dermis of the skin. Hence, depth is an important factor to diagnose melanoma. This paper introduces a non-invasive computerized dermoscopy system that considers the estimated depth of skin lesions for diagnosis. A 3-D skin lesion reconstruction technique using the estimated depth obtained from regular dermoscopic images is presented. On basis of the 3-D reconstruction, depth and 3-D shape features are extracted...
2017: IEEE Journal of Translational Engineering in Health and Medicine
https://www.readbyqxmd.com/read/28507827/wearable-improved-vision-system-for-color-vision-deficiency-correction
#3
Paolo Melillo, Daniel Riccio, Luigi Di Perna, Gabriella Sanniti Di Baja, Maurizio De Nino, Settimio Rossi, Francesco Testa, Francesca Simonelli, Maria Frucci
Color vision deficiency (CVD) is an extremely frequent vision impairment that compromises the ability to recognize colors. In order to improve color vision in a subject with CVD, we designed and developed a wearable improved vision system based on an augmented reality device. The system was validated in a clinical pilot study on 24 subjects with CVD (18 males and 6 females, aged 37.4 ± 14.2 years). The primary outcome was the improvement in the Ishihara Vision Test score with the correction proposed by our system...
2017: IEEE Journal of Translational Engineering in Health and Medicine
https://www.readbyqxmd.com/read/28507826/near-infrared-imaging-for-detecting-caries-and-structural-deformities-in-teeth
#4
Keith Angelino, David A Edlund, Pratik Shah
2-D radiographs, while commonly used for evaluating sub-surface hard structures of teeth, have low sensitivity for early caries lesions, particularly those on tooth occlusal surfaces. Radiographs are also frequently refused by patients over safety concerns. Translucency of teeth in the near-infrared (NIR) range offers a non-ionizing and safe approach to detect dental caries. We report the construction of an NIR (850 nm) LED imaging system, comprised of an NIR source and an intraoral camera for rapid dental evaluations...
2017: IEEE Journal of Translational Engineering in Health and Medicine
https://www.readbyqxmd.com/read/28507825/spatiotemporal-strategies-for-joint-segmentation-and-motion-tracking-from-cardiac-image-sequences
#5
Huafeng Liu, Ting Wang, Lei Xu, Pengcheng Shi
Although accurate and robust estimations of the deforming cardiac geometry and kinematics from cine tomographic medical image sequences remain a technical challenge, they have significant clinical value. Traditionally, boundary or volumetric segmentation and motion estimation problems are considered as two sequential steps, even though the order of these processes can be different. In this paper, we present an integrated, spatiotemporal strategy for the simultaneous joint recovery of these two ill-posed problems...
2017: IEEE Journal of Translational Engineering in Health and Medicine
https://www.readbyqxmd.com/read/28507824/non-invasive-radiofrequency-field-treatment-to-produce-hepatic-hyperthermia-efficacy-and-safety-in-swine
#6
Jason C Ho, Lam Nguyen, Justin J Law, Matthew J Ware, V Keshishian, N C Lara, Trac Nguyen, Steven A Curley, Stuart J Corr
The Kanzius non-invasive radio-frequency hyperthermia system (KNiRFH) has been investigated as a treatment option for hepatic hyperthermia cancer therapy. The treatment involves exposing the patient to an external high-power RF (13.56 MHz) electric field, whereby the propagating waves penetrate deep into the tumor causing targeted heating based on differential tissue dielectric properties. However, a comprehensive examination of the Kanzius system alongside any associated toxicities and its ability to induce hepatic hyperthermia in larger animal models, such as swine, are the subjects of the work herein...
2017: IEEE Journal of Translational Engineering in Health and Medicine
https://www.readbyqxmd.com/read/28560119/collaborative-paradigm-of-preventive-personalized-and-precision-medicine-with-point-of-care-technologies
#7
Atam P Dhawan
Recent advances in biosensors, medical instrumentation, and information processing and communication technologies (ICT) have enabled significant improvements in healthcare. However, these technologies have been mainly applied in clinical environments, such as hospitals and healthcare facilities, under managed care by well-trained and specialized individuals. The global challenge of providing quality healthcare at affordable cost leads to the proposed paradigm of P reventive, Personalized, and Precision Medicine that requires a seamless use of technology and infrastructure support for patients and healthcare providers at point-of-care (POC) locations including homes, semi or pre-clinical facilities, and hospitals...
2016: IEEE Journal of Translational Engineering in Health and Medicine
https://www.readbyqxmd.com/read/28560118/low-cost-sensor-system-design-for-in-home-physical-activity-tracking
#8
Siddhartha Nambiar, Alexander Nikolaev, Melissa Greene, Lora Cavuoto, Ann Bisantz
An aging and more sedentary population requires interventions aimed at monitoring physical activity, particularly within the home. This research uses simulation, optimization, and regression analyses to assess the feasibility of using a small number of sensors to track movement and infer physical activity levels of older adults. Based on activity data from the American Time Use Survey and assisted living apartment layouts, we determined that using three to four doorway sensors can be used to effectively capture a sufficient amount of movements in order to estimate activity...
2016: IEEE Journal of Translational Engineering in Health and Medicine
https://www.readbyqxmd.com/read/28560117/a-comparison-of-pattern-recognition-control-and-direct-control-of-a-multiple-degree-of-freedom-transradial-prosthesis
#9
Todd A Kuiken, Laura A Miller, Kristi Turner, Levi J Hargrove
With existing conventional prosthesis control (direct control), individuals with a transradial amputation use two opposing muscle groups to control each prosthesis motor. As component complexity increases, subjects must switch the prosthesis into different modes to control each component in sequence. Pattern recognition control offers the ability to control multiple movements in a seamless manner without switching. In this paper, three individuals with a transradial amputation completed a home trial to compare direct control and pattern recognition control of a multiple degree-of-freedom prosthesis...
2016: IEEE Journal of Translational Engineering in Health and Medicine
https://www.readbyqxmd.com/read/28439481/sit-to-stand-transition-reveals-acute-fall-risk-in-activities-of-daily-living
#10
Tomislav Pozaic, Ulrich Lindemann, Anna-Karina Grebe, Wilhelm Stork
The focus of this paper was on finding wrist sensor-derived features for detecting highly acute fall risk from the sit-to-stand transitions performed in a non-ambulatory environment. Furthermore, the influence of the dominant and non-dominant hand on these features was investigated. A cohort of 174 older subjects was monitored for seven consecutive days in their home setting by using inertial sensors attached at the wrist. Based on the reported falls during a one-month follow-up phase, two groups were defined...
2016: IEEE Journal of Translational Engineering in Health and Medicine
https://www.readbyqxmd.com/read/28424753/image-guided-high-intensity-focused-ultrasound-system-for-large-animal-nerve-ablation-studies
#11
Arthur Worthington, Philip Peng, Kevin Rod, Vera Bril, Jahan Tavakkoli
High intensity focused ultrasound (HIFU) is a form of thermal ablation technique, which can treat a variety of medical afflictions. One promising therapeutic use is the permanent destruction of nerves non-invasively in patients with severe spasticity or certain types of pain (e.g., phantom limb pain). To this end, HIFU requires ultrasound guidance, which allows the non-invasive, target-specific deposition of thermal energy to the targeted nerve, thereby blocking axonal conduction. In this paper, a composite system comprising both ultrasound-imaging and HIFU therapy was developed and used to induce localized non-invasive nerve blockage in an in vivo large animal study...
2016: IEEE Journal of Translational Engineering in Health and Medicine
https://www.readbyqxmd.com/read/27957405/smart-helmet-wearable-multichannel-ecg-and-eeg
#12
Wilhelm Von Rosenberg, Theerasak Chanwimalueang, Valentin Goverdovsky, David Looney, David Sharp, Danilo P Mandic
Modern wearable technologies have enabled continuous recording of vital signs, however, for activities such as cycling, motor-racing, or military engagement, a helmet with embedded sensors would provide maximum convenience and the opportunity to monitor simultaneously both the vital signs and the electroencephalogram (EEG). To this end, we investigate the feasibility of recording the electrocardiogram (ECG), respiration, and EEG from face-lead locations, by embedding multiple electrodes within a standard helmet...
2016: IEEE Journal of Translational Engineering in Health and Medicine
https://www.readbyqxmd.com/read/27957404/effects-of-real-world-versus-virtual-environments-on-joint-excursions-in-full-body-reaching-tasks
#13
James S Thomas, Christopher R France, Samuel T Leitkam, Megan E Applegate, Peter E Pidcoe, Stevan Walkowski
Starting from an upright standing posture and reaching for a target that requires some forward bending of the trunk can involve many different configurations of the trunk and limb segments. We sought to determine if configurations of the limb and trunk segments during our standardized full-body reaching tasks were influenced by the visual environment. This paper examined movement patterns of healthy participants ([Formula: see text], eight female and nine male) performing full body reaching tasks to: 1) real-world targets; 2) virtual targets presented on a 3-D television; and 3) virtual targets presented using a head-mounted display...
2016: IEEE Journal of Translational Engineering in Health and Medicine
https://www.readbyqxmd.com/read/27777829/non-invasive-neuromodulation-using-time-varying-caloric-vestibular-stimulation
#14
Robert D Black, Lesco L Rogers, Kristen K Ade, Heather A Nicoletto, Heather D Adkins, Daniel T Laskowitz
Caloric vestibular stimulation (CVS) to elicit the vestibulo-ocular reflex has long been used in clinical settings to aid in the diagnosis of balance disorders and to confirm the absence of brainstem function. While a number of studies have hinted at the potential therapeutic applications of CVS, the limitations of existing devices have frustrated that potential. Current CVS irrigators use water or air during short-duration applications; however, this approach is not tenable for longer duration therapeutic protocols or home use...
2016: IEEE Journal of Translational Engineering in Health and Medicine
https://www.readbyqxmd.com/read/27766188/healthcare-commercialization-programs-improving-the-efficiency-of-translating-healthcare-innovations-from-academia-into-practice
#15
John M Collins, Ofer Reizes, Michael K Dempsey
Academic investigators are generating a plethora of insights and technologies that have the potential to significantly improve patient care. However, to address the imperative to improve the quality, cost and access to care with ever more constrained funding, the efficiency and the consistency with which they are translated into cost effective products and/or services need to improve. Healthcare commercialization programs (HCPs) are described and proposed as an option that institutions can add to their portfolio to improve translational research...
2016: IEEE Journal of Translational Engineering in Health and Medicine
https://www.readbyqxmd.com/read/27766187/summary-of-human-ankle-mechanical-impedance-during-walking
#16
Hyunglae Lee, Elliott J Rouse, Hermano Igo Krebs
The human ankle joint plays a critical role during walking and understanding the biomechanical factors that govern ankle behavior and provides fundamental insight into normal and pathologically altered gait. Previous researchers have comprehensively studied ankle joint kinetics and kinematics during many biomechanical tasks, including locomotion; however, only recently have researchers been able to quantify how the mechanical impedance of the ankle varies during walking. The mechanical impedance describes the dynamic relationship between the joint position and the joint torque during perturbation, and is often represented in terms of stiffness, damping, and inertia...
2016: IEEE Journal of Translational Engineering in Health and Medicine
https://www.readbyqxmd.com/read/27730016/a-system-for-simple-real-time-anastomotic-failure-detection-and-wireless-blood-flow-monitoring-in-the-lower-limbs
#17
Michael A Rothfuss, Nicholas G Franconi, Jignesh V Unadkat, Michael L Gimbel, Alexander Star, Marlin H Mickle, Ervin Sejdic
Current totally implantable wireless blood flow monitors are large and cannot operate alongside nearby monitors. To alleviate the problems with the current monitors, we developed a system to monitor blood flow wirelessly, with a simple and easily interpretable real-time output. To the best of our knowledge, the implanted electronics are the smallest in reported literature, which reduces bio-burden. Calibration was performed across realistic physiological flow ranges using a syringe pump. The device's sensors connected directly to the bilateral femoral veins of swine...
2016: IEEE Journal of Translational Engineering in Health and Medicine
https://www.readbyqxmd.com/read/27730015/the-national-institutes-of-health-affordable-cancer-technologies-program-improving-access-to-resource-appropriate-technologies-for-cancer-detection-diagnosis-monitoring-and-treatment-in-low-and-middle-income-countries
#18
Paul C Pearlman, Rao Divi, Michael Gwede, Pushpa Tandon, Brian S Sorg, Miguel R Ossandon, Lokesh Agrawal, Vinay Pai, Houston Baker, Tiffani Bailey Lash
Point-of-care (POC) technologies have proved valuable in cancer detection, diagnosis, monitoring, and treatment in the developed world, and have shown promise in low-and-middle-income countries (LMIC) as well. Despite this promise, the unique design constraints presented in low-resource settings, coupled with the variety of country-specific regulatory and institutional dynamics, have made it difficult for investigators to translate successful POC cancer interventions to the LMIC markets. In response to this need, the National Cancer Institute has partnered with the National Institute of Biomedical Imaging and Bioengineering to create the National Institutes of Health Affordable Cancer Technologies (ACTs) program...
2016: IEEE Journal of Translational Engineering in Health and Medicine
https://www.readbyqxmd.com/read/27730014/national-institute-of-biomedical-imaging-and-bioengineering-point-of-care-technology-research-network-advancing-precision-medicine
#19
Penny Ford Carleton, Steven Schachter, John A Parrish, John M Collins, J Benjamin Crocker, Ronald F Dixon, Susan Edgman-Levitan, Kent B Lewandrowski, James E Stahl, Catherine Klapperich, Mario Cabodi, Charlotte A Gaydos, Anne M Rompalo, Yukari Manabe, Tza-Huei Wang, Richard Rothman, Chris D Geddes, Lea Widdice, Joany Jackman, Rishi A Mathura, Tiffani Bailey Lash
To advance the development of point-of-care technology (POCT), the National Institute of Biomedical Imaging and Bioengineering established the POCT Research Network (POCTRN), comprised of Centers that emphasize multidisciplinary partnerships and close facilitation to move technologies from an early stage of development into clinical testing and patient use. This paper describes the POCTRN and the three currently funded Centers as examples of academic-based organizations that support collaborations across disciplines, institutions, and geographic regions to successfully drive innovative solutions from concept to patient care...
2016: IEEE Journal of Translational Engineering in Health and Medicine
https://www.readbyqxmd.com/read/27730013/the-importance-of-state-and-context-in-safe-interoperable-medical-systems
#20
Sandy Weininger, Michael B Jaffe, Michael Robkin, Tracy Rausch, David Arney, Julian M Goldman
This paper describes why "device state" and "patient context" information are necessary components of device models for safe interoperability. This paper includes a discussion of the importance of describing the roles of devices with respect to interactions (including human user workflows involving devices, and device to device communication) within a system, particularly those intended for use at the point-of-care, and how this role information is communicated. In addition, it describes the importance of clinical scenarios in creating device models for interoperable devices...
2016: IEEE Journal of Translational Engineering in Health and Medicine
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