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Epilepsy & Behavior Case Reports

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https://www.readbyqxmd.com/read/29707476/evaluation-of-perampanel-as-monotherapy-for-focal-seizures-experience-from-open-label-extension-studies
#1
Patrick Kwan, Scott Mintzer, Antonio Laurenza, Anna Patten, Karen Cartwright
Perampanel, a selective, non-competitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist, is approved for adjunctive treatment of focal seizures, with or without secondarily generalized seizures, and for primary generalized tonic-clonic seizures in patients with epilepsy aged ≥ 12 years. Perampanel was recently approved for monotherapy use for focal seizures in the U.S.A. Anti-seizure drug monotherapy may be preferable to polytherapy, which is generally associated with increased toxicity, non-compliance, and cost...
2018: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/29692973/visual-hallucinations-a-novel-complication-after-hemispherectomy
#2
Jonas Vanags, Monisha Sachdev, Gerald Grant, Mohamad A Mikati
Two patients at our center experienced florid visual hallucinations following hemispherectomy. The first patient had drug-resistant left hemispheric focal seizures at 20 months of age from a previous stroke. Following functional hemispherectomy at age 3, he experienced frightening hallucinations 1 month post-operatively lasting 3.5 months. Our second patient underwent subtotal hemispherectomy at age 6 for drug-resistant focal seizures from right hemispheric cortical dysplasia. Eighteen months later he developed scary visual hallucinations during which he would shout and throw things...
2018: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/29692972/postictal-neurogenic-pulmonary-edema-case-report-and-brief-literature-review
#3
Oscar Mauricio Romero Osorio, Juan Felipe Abaunza Camacho, Diana Sandoval Briceño, Pieralessandro Lasalvia, Daniel Narino Gonzalez
Cardiopulmonary complications associated with epilepsy are generally associated with generalized tonic-clonic seizures, as a consequence of systemic adrenergic discharge and release of inflammatory mediators. We present a case of a 34-year-old woman with a history of Focal epilepsy since adolescence, who presented self-limited pulmonary edema following a focal to bilateral tonic-clonic seizure with subsequent resolution of the symptoms. We also made a brief review of neurogenic pulmonary edema, its proposed pathophysiology, treatment and its relation with sudden unexpected death in epilepsy (SUDEP)...
2018: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/29692971/seizure-freedom-following-surgery-for-multi-focal-epilepsy-due-to-cerebral-malaria
#4
Peraya Piromruen, Chusak Limotai
No abstract text is available yet for this article.
2018: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/29692970/language-recovery-after-epilepsy-surgery-of-the-broca-s-area
#5
Lilit Mnatsakanyan, Sumeet Vadera, Christopher W Ingalls, Jie Zheng, Mona Sazgar, Frank P Hsu, Jack J Lin
Epilepsy surgery is indicated in select patients with drug-resistant focal epilepsy. Seizure freedom or significant reduction of seizure burden without risking new neurological deficits is the expected goal of epilepsy surgery. Typically, when the seizure onset zone overlaps with eloquent cortex, patients are excluded from surgery. We present a patient with drug-resistant frontal lobe epilepsy who underwent successful surgery with resection of Broca's area, primarily involving the pars triangularis (BA 45)...
2018: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/29692969/emotional-stimuli-provoked-seizures-potentially-misdiagnosed-as-psychogenic-non-epileptic-attacks-a-case-of-temporal-lobe-epilepsy-with-amygdala-enlargement
#6
Hidetaka Tamune, Go Taniguchi, Susumu Morita, Yousuke Kumakura, Shinsuke Kondo, Kiyoto Kasai
The association between emotional stimuli and temporal lobe epilepsy (TLE) is largely unknown. Here, we report the case of a depressed, 50-year-old female complaining of episodes of a "spaced out" experience precipitated by emotional stimuli. Psychogenic non-epileptic attacks were suspected. However, video-EEG coupled with emotional stimuli-provoked procedures and MRI findings of amygdala enlargement, led to the diagnosis of left TLE. Accurate diagnosis and explanation improved her subjective depression and seizure frequency...
2018: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/29692968/pilot-data-on-responsive-epilepsy-neurostimulation-measures-of-sleep-apnea-and-continuous-glucose-measurements
#7
Katie M Kinnear, Nicole M Warner, Anand Gersappe, Michael J Doherty
Objectives: To match responsive neurostimulator (RNS) and polysomnographic data to determine if RNS detections and stimulations correlate with measurements of sleep disordered breathing and continuous glucose measurements (CGM). Materials and methods: In a patient with an RNS with detection/stimulation leads implanted bi-temporally detection-stimulation counts were matched by time with coinciding polysomnogram and CGM data. Results: Temporal dispersion of RNS DSC were independent of measures of sleep apnea, hypopnea or glucose...
2018: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/29692967/can-the-combination-of-hyperthermia-seizures-and-ion-channel-dysfunction-cause-fatal-post-ictal-cerebral-edema-in-patients-with-scn1a-mutations
#8
Carina Büren, Marcel Alexander Kamp, Christopher Munoz-Bendix, Hans-Jakob Steiger, Joachim Windolf, Maxine Dibué-Adjei
A 21-year-old male with an SCN1A mutation died of cerebral herniation 3 h after a seizure occurring during physical activity. Cases of fatal cerebral edema in patients with SCN1A mutations after fever and status epilepticus have been recently reported raising the question whether sodium channel dysfunction may contribute to cerebral edema and thereby contribute to the increased premature mortality in Dravet Syndrome. We report on our patient and discuss whether the combination of hyperthermia and ion channel dysfunction may not only trigger seizures but also a fatal pathophysiological cascade of cerebral edema and herniation leading to cardiorespiratory collapse...
2018: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/29692966/conjoint-glutamic-acid-decarboxylase-65-and-p-q-voltage-gated-calcium-channel-antibodies-in-autoimmune-epilepsy-a-case-report
#9
Mohamed AlKhaja, Ammar AlKawi, Mahmoud Abu-Ata, Asma Mohammaddin
Numerous autoantibodies are implicated in the pathogenesis of autoimmune epilepsy. In the past decade, many case series reported the association of glutamic acid decarboxylase 65 (GAD 65) antibodies with epilepsy. Conjoint presence of GAD 65 antibodies with antinuclear, anti-thyroid, and anti-parietal cell antibodies has often been demonstrated. However, concomitant elevated levels of GAD 65 and P/Q voltage gated calcium channel (VGCC) antibodies is rare. We report a case of autoimmune epilepsy with conjoint GAD 65 and P/Q VGCC antibodies in the absence of malignancy...
2018: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/29692965/sub-lobar-dysplasia-a-comprehensive-evaluation-with-neuroimaging-magnetoencephalography-and-histopathology
#10
Kenchaiah Raghavendra, Ganne Chaitanya, Bhargava Goutham, Anita Mahadevan, Ravindranadh Chowdary Mundlamuri, Rose Dawn Bharath, Mariyappa Narayannan, Malla Bhaskar Rao, Arimappamagan Arivazhagan, Parthasarthy Satishchandra, Sanjib Sinha
Sublobar dysplasia, a rare cortical malformation has been defined in only 8 patients to date. It was identified on the basis of histopathological features and MRI findings. We report a right temporal sublobar dysplasia, with detailed evaluation including neuroimaging, magnetoencephalography and histopathology to further characterize the pathology. Additional pathological features included a deep collateral sulcus in the basal right temporal lobe, thinned out right corticospinal tract, and bilateral asymmetric basal ganglia changes...
2018: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/29692964/recurrent-catamenial-status-epilepticus-is-it-rare-or-an-under-recognized-phenomenon-in-women-with-epilepsy
#11
Albi J Chalissery, Emer Murphy, Gerard Mullins, Peter Widdess-Walsh, Ronan Kilbride, Norman Delanty
•Recurrent catamenial status epilepticus may occur in generalized and focal epilepsy.•Documenting the menstrual cycles and perimenstrual video-EEG help the diagnosis.•Hormonal treatment including menstrual suppressive therapies may be used.
2018: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/29692963/anterior-corpus-callosotomy-in-patients-with-drug-resistant-epilepsy-invasive-eeg-findings-and-seizure-outcomes
#12
Olga Taraschenko, Swetha Pedavally, Kaeli K Samson, Mark J Puccioni, Deepak Madhavan
Corpus callosotomy (CC) is used in patients with drug-resistant seizures who are not candidates for excisional surgery and failed neurostimulation. We examined ictal scalp and intracranial electroencephalogram (iEEG) recordings in 16 patients being evaluated for anterior CC alone or CC in combination with focal resection, to determine the role of the iEEG in predicting postoperative seizure outcomes. In our cohort, CC improved generalized atonic seizures and focal seizures with impaired awareness but did not alter outcomes for generalized tonic-clonic or tonic seizures...
2018: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/29692962/development-and-use-of-the-art-therapy-seizure-assessment-sculpture-on-an-inpatient-epilepsy-monitoring-unit
#13
Sarah E Brown, Tamara Shella, Elia Pestana-Knight
•Patients diagnosed with PNES created sculptures notably different than patients diagnosed with epilepsy.•Art therapy may help both PNES and Epilepsy patients with emotional expression.•Along with a conventional diagnostic interview, SAS could help could provide important information at a much quicker rate.
2018: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/29387536/an-interaction-between-warfarin-and-cannabidiol-a-case-report
#14
Leslie Grayson, Brannon Vines, Kate Nichol, Jerzy P Szaflarski
•An interaction between warfarin and cannabidiol is described•The mechanisms of cannabidiol and warfarin metabolism are reviewed•Mechanism of the interaction is proposed•INR should be monitored in patients when cannabinoids are introduced.
2018: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/29379714/hemispherotomy-for-late-post-traumatic-super-refractory-status-epilepticus-in-an-adult
#15
Raghavendra Nayak, Vivek Mathew, Ramanan Rajgopal, Krishnaprabhu Raju
No abstract text is available yet for this article.
2017: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/29204348/non-ictal-onset-zone-a-window-to-ictal-dynamics
#16
Pegah Afra, Sara J Hanrahan, Spencer Sterling Kellis, Paul House
The focal and network concepts of epilepsy present different aspects of electroclinical phenomenon of seizures. Here, we present a 23-year-old man undergoing surgical evaluation with left fronto-temporal electrocorticography (ECoG) and microelectrode-array (MEA) in the middle temporal gyrus (MTG). We compare action-potential (AP) and local field potentials (LFP) recorded from MEA with ECoG. Seizure onset in the mesial-temporal lobe was characterized by changes in the pattern of AP-firing without clear changes in LFP or ECoG in MTG...
2017: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/29204347/impairment-of-consciousness-induced-by-bilateral-electrical-stimulation-of-the-frontal-convexity
#17
Imran H Quraishi, Christopher F Benjamin, Dennis D Spencer, Hal Blumenfeld, Rafeed Alkawadri
We report a case of impairment of consciousness (IOC) induced by electrical cortical stimulation (ECS) of homologous regions within the lateral frontal convexities in a patient with medically intractable epilepsy. The patient had mixed features of idiopathic generalized and focal epilepsy. On intracranial EEG recording, interictal and ictal discharges showed a high degree of synchrony across widespread bilateral fronto-parietal areas. We identified regions in the lateral frontal lobes that reliably and produced loss of consciousness by ECS...
2017: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/29204346/drug-induced-hypersensitivity-syndrome-caused-by-valproic-acid-as-a-monotherapy-for-epilepsy-first-case-report-in-asian-population
#18
X T Wu, P W Hong, D J Suolang, D Zhou, H Stefan
Valproic acid (VPA) is a broad-spectrum antiseizure drug used for a variety of clinical conditions, such as epilepsy and mood disorders. Drug-induced hypersensitivity syndrome (DRESS) accompanied by hyponatremia, thrombocytopenia, hypoalbuminemia and elevated aminotransferase has never been reported as an adverse effect of VPA monotherapy during titration for epilepsy in Asian population. Hereby, we present the case of a 73-year-old Chinese male who suffered from DRESS and other complications two weeks after initiating VPA treatment for epilepsy...
2017: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/29204345/localization-of-ictal-pouting-in-frontal-lobe-epilepsy-a-case-report
#19
Guray Koc, Semai Bek, Zeki Gokcil
No abstract text is available yet for this article.
2017: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/29159067/poor-neurologic-outcomes-after-cardiac-arrest-a-spectrum-with-individual-implications
#20
Rachel Beekman, David M Greer, Carolina B Maciel
No abstract text is available yet for this article.
2017: Epilepsy & Behavior Case Reports
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