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Epilepsy & Behavior Case Reports

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https://www.readbyqxmd.com/read/27896067/relationship-between-high-frequency-oscillations-and-spikes-in-a-case-of-temporal-lobe-epilepsy
#1
Vishwanath Sagi, M Steven Evans
OBJECTIVE: The aim of this case report was to study the relationship between high-frequency oscillations (HFOs), spikes, and seizures in a patient with temporal lobe epilepsy. INTRODUCTION: During intracranial electroencephalography (EEG), HFOs are thought to be a marker for the seizure onset zone (SOZ). High-frequency oscillations are classified into ripples with frequencies of 70-200 Hz and fast ripples with frequencies of 200-500 Hz. Although HFOs are thought to be a marker for the SOZ, their relationship to spikes has not been studied in detail, especially within the SOZ...
2016: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/27896066/acth-therapy-for-west-syndrome-with-severe-hemophilia-a
#2
Kazuo Kubota, Yoriko Kinomura, Takahiro Yamamoto, Michio Ozeki, Minako Kawamoto, Norio Kawamoto, Toshiyuki Fukao
Hemophilia A is an X-linked recessive disorder caused by factor VIII deficiency, which is an important factor in the coagulation system. Here, we describe a 1-year-old boy with hemophilia A who developed West syndrome (WS). Recombinant factor VIII was administered during adrenocorticotropic hormone (ACTH) therapy to prevent intracranial hemorrhage. Infusion of factor VIII at fixed intervals is useful for the safe administration of ACTH therapy for patients with WS with severe hemophilia A. A coagulation screening test should be performed before ACTH therapy...
2016: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/27830116/headache-maybe-the-initial-symptom-in-rasmussen-s-syndrome-a-child-case-report
#3
Zhiliang Yang, Guilian Sun
OBJECTIVE: The aim of this case report was to study that headache maybe the initial symptom in Rasmussen's syndrome (RS). INTRODUCTION: Headache has not yet been reported as prodromal symptom. METHODS: We studied a case of RS in which the patient experienced a recurring headache for about one year prior to the onset of partial seizures. RESULTS: Magnetic resonance imaging (MRI) results were normal when the headache first occurred and showed left brain atrophy three years later...
2016: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/27668182/unusual-atypical-language-lateralization
#4
Muhammad T Khan, Roger Oghlakian, Mohamad Z Koubeissi
Determining the language-dominant hemisphere is essential for planning epilepsy surgery. A 60-year-old right-handed woman with epilepsy since age 16 failed a partial right anterior lobectomy at age 21. Later, a brain MRI found extensive right-sided cortical dysplasia and periventricular heterotopia. Subsequently, prolonged video-EEG monitoring localized her seizures to the right temporoparietal region. Functional MRI was inconclusive in lateralizing her language, prompting a Wada test, which strongly lateralized language to the right...
2016: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/27668181/individualizing-therapies-with-responsive-epilepsy-neurostimulation-a-mirtazapine-case-study-of-hippocampal-excitability
#5
Nicole M Warner, Ryder P Gwinn, Michael J Doherty
OBJECTIVES: This study aimed to investigate mirtazapine-induced changes in responsive neurostimulator (RNS) recordings in a patient with epilepsy. MATERIALS AND METHODS: Cortical detection/stimulation counts from an RNS implanted in a patient with bitemporal epilepsy were matched to mirtazapine use to see if that drug altered hippocampal excitability. RESULTS: Mirtazapine decreased hippocampal stability; when mirtazapine was held after a washout period, DSC counts declined, but when it was retrialed, DSC counts increased...
2016: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/27668180/a-case-report-on-the-efficacy-of-vigabatrin-analogue-1s-3s-3-amino-4-difluoromethylenyl-1-cyclopentanoic-acid-cpp-115-in-a-patient-with-infantile-spasms
#6
Kyra Doumlele, Erin Conway, Julie Hedlund, Patricia Tolete, Orrin Devinsky
West Syndrome is characterized by infantile spasms, a hypsarrhythmic electroencephalogram (EEG) pattern, and a poor neurodevelopmental prognosis. First-line treatments include adrenocorticotrophic hormone (ACTH) and vigabatrin, but adverse effects often limit their use. CPP-115 is a high-affinity vigabatrin analogue developed to increase therapeutic potency and to limit retinal toxicity. Here, we present a child treated with CPP-115 through an investigational new drug protocol who experienced a marked reduction of seizures with no evidence of retinal dysfunction...
2016: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/27668179/a-case-of-symptomatic-reflex-epilepsy-precipitated-by-bathing
#7
Sachin Sureshbabu, Dinesh Nayak, Sudhir Peter, Chindripu Sobhana, Gaurav Mittal, Vikash Aggarwal
No abstract text is available yet for this article.
2016: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/27668178/controllable-yawning-expressed-as-focal-seizures-of-frontal-lobe-epilepsy
#8
Vibhangini S Wasade, Indranil Balki, Susan M Bowyer, Shaila Gaddam, Ali-Reza Mohammadi-Nejad, Mohammad-Reza Nazem-Zadeh, Hamid Soltanian-Zadeh, Andrew Zillgitt, Marianna Spanaki-Varelas
Excessive yawning was described in some neurological conditions as part of periictal or ictal manifestations of epilepsy, most commonly temporal lobe. We present the first case of controllable yawning as a primary seizure semiology with dominant frontal lobe involvement in a 20-year-old man. Video electroencephalography recorded 8 yawning episodes accompanied with right arm movement correlating with rhythmic diffuse theta range activity with left hemispheric predominance. Magnetoencephalography coherence source imaging was consistent with persistent neuronal networks with areas of high coherence reliably present over the left lateral orbitofrontal region...
2016: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/27660746/acute-intermittent-porphyria-presenting-with-posterior-reversible-encephalopathy-syndrome-and-lateralized-periodic-discharges-plus-fast-activity-on-eeg
#9
Diosely C Silveira, Mahrukh Bashir, Joshua Daniel, Michelle H Lucena, Frank Bonpietro
We report on a 20-year-old patient with a 6-month history of recurrent abdominal pain and a 3-day history of vomiting, hypertension, seizures, and encephalopathy. The brain MRI showed posterior reversible encephalopathy syndrome, and continuous EEG (cEEG) monitoring showed lateralized periodic discharges plus fast activity. Comprehensive CSF studies were negative. Because of severe abdominal pain without a definite etiology, we requested urine porphobilinogen and serum and fecal porphyrins, which suggested acute intermittent porphyria (AIP)...
2016: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/27630818/fantastic-confabulation-in-right-frontal-lobe-epilepsy
#10
Mayu Fujikawa, Yoshiyuki Nishio, Yosuke Kakisaka, Nanayo Ogawa, Masaki Iwasaki, Nobukazu Nakasato
BACKGROUND: Interictal behavioral symptoms in frontal lobe epilepsy (FLE) are variable and often difficult to discriminate from other localization-related epilepsies. METHODS AND RESULTS: We report two female patients with right FLE who exhibited fantastic confabulations. One of the patients had a 14-year history of hypermotor seizures, and the other had a 10-year history of dyscognitive seizures with automatism. Their fantastic confabulations arose in the context of moderate-to-severe cognitive impairment and of a variety of behavioral abnormalities, including emotional withdrawal and compulsive behaviors...
2016: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/27630817/praxis-induced-reflex-seizures-mainly-precipitated-by-writing-due-to-a-parietal-focal-cortical-dysplasia
#11
Frédéric Racicot, Sami Obaid, Alain Bouthillier, Laurent Guillon-Létourneau, Jean-François Clément, Dang Khoa Nguyen
We report the case of a 23-year-old left-handed woman with medically intractable praxis-induced reflex seizures mainly precipitated by writing. Selective resection of subtle end-of-sulcus cortical dysplasia in the right inferior parietal lobule resulted in freedom from seizures. To the best of our knowledge, this is the first case of praxis-induced reflex seizures mainly precipitated by writing in which a focal lesion was found and treated successfully by surgery.
2016: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/27579251/-tickling-seizures-originating-in-the-left-frontoparietal-region
#12
Jessica J Falco-Walter, Michael Stein, Maggie McNulty, Lubov Romantseva, Peter Heydemann
We report a 10-year-old boy with mild developmental delay and epilepsy with new events of right back tickling and emotional upset. These initially appeared behavioral, causing postulation of habit behaviors or psychogenic nonepileptic seizures. Several ictal and interictal EEGs were unrevealing. Continuous EEG revealed only poorly localized frontal ictal activity. Given that his clinical symptoms suggested a parietal localization, double-density EEG electrodes were placed to better localize the epileptogenic and symptomatogenic zones...
2016: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/27504264/atypical-benign-partial-epilepsy-of-childhood-with-acquired-neurocognitive-lexical-semantic-and-autistic-spectrum-disorder
#13
Nicholas M Allen, Judith Conroy, Thierry Deonna, Dara McCreary, Paul McGettigan, Cathy Madigan, Imogen Carter, Sean Ennis, Sally A Lynch, Amre Shahwan, Mary D King
Atypical benign partial epilepsy (ABPE) of childhood or pseudo-Lennox syndrome is a form of idiopathic focal epilepsy characterized by multiple seizure types, focal and/or generalized epileptiform discharges, continuous spike-wave during sleep (CSWS), and sometimes reversible neurocognitive deficits. There are few reported cases of ABPE describing detailed correlative longitudinal follow-up of the various associated neurocognitive, language, social communicative, or motor deficits, in parallel with the epilepsy...
2016: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/27504263/wolf-hirschhorn-4p-syndrome-with-west-syndrome
#14
Hirotaka Motoi, Tohru Okanishi, Sotaro Kanai, Takuya Yokota, Tomohiro Yamazoe, Mitsuyo Nishimura, Ayataka Fujimoto, Takamichi Yamamoto, Hideo Enoki
Wolf-Hirschhorn syndrome (WHS) is a chromosome disorder (4p-syndrome) which is characterized by craniofacial features and epileptic seizures. Here, we report a case of WHS with West syndrome, in whom the seizures were refractory to several antiepileptic drugs but were responsive to the addition of lamotrigine. The patient had epileptic spasms at age seven months. The interictal electroencephalogram was hypsarrhythmic. After adding lamotrigine, seizures decreased remarkably, and spasms disappeared. We have identified and described the very rare case of a girl with WHS who also developed West syndrome...
2016: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/27489775/forced-normalization-s-converse-as-nature-s-model-for-use-of-ect-in-the-management-of-psychosis-an-observational-case-series
#15
Andrea L Green, Patrick H Harmon, F Austin Boyer, Kamil Detyniecki, Maria G Motlagh, Predrag V Gligorovic
No abstract text is available yet for this article.
2016: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/27489774/lgi1-negative-faciobrachial-dystonic-like-seizures-originating-from-the-insula
#16
Riddhi Patira, Vidita Khatri, Camilo Gutierrez, Sarah Zubkov
We expand the differential diagnosis of LGI1-positive faciobrachial dystonic seizures (FBDS) by presenting a 67-year-old woman affected by seizures of similar semiology who was found to have insular epilepsy. We report the distinct characteristics of insular faciobrachial dystonic-like seizures that would help clinicians to differentiate them from typical LGI1-positive FBDS, thus, guiding therapy while awaiting antibody results. LGI1-negative faciobrachial dystonic-like seizures should be considered when the seizure semiology includes unilateral and prolonged dystonia without loss of awareness, there is an ictal EEG correlate, MRI is suggestive of insular lesion, and when there is neither clearly associated memory impairment nor hyponatremia...
2016: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/27453818/successful-hemispherotomy-for-a-patient-with-intractable-epilepsy-secondary-to-bilateral-congenital-brain-malformation-with-lateralized-pyramidal-tract-of-diffusion-tensor-image-tractography
#17
Yuri Nagai, Ayataka Fujimoto, Tohru Okanishi, Hironao Motoi, Sotaro Kanai, Takuya Yokota, Hideo Enoki, Mitsuyo Nishimura, Takamichi Yamamoto
PURPOSE: To perform an epilepsy surgery on a patient with drug resistant epilepsy secondary to bilateral brain malformation. The patient was a 2-year 9-month-old boy who had congenital bilateral multiple abnormalities. He developed a complex partial seizure at 9 months old. Based on the presurgical evaluations, he underwent a right hemispherotomy. RESULTS: Brain MRI revealed congenital bilateral polymicrogyria, right schizencephaly, and corpus callosum agenesis...
2016: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/27437182/add-on-perampanel-in-lance-adams-syndrome
#18
Bernhard J Steinhoff, Matthias Bacher, Christoph Kurth, Anke M Staack, Reinhold Kornmeier
Perampanel (PER) is the first-in-class selective, noncompetitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist that has been licensed and marketed as antiepileptic drug (AED) indicated for patients with partial-onset and primary generalized tonic-clonic seizures. A positive effect was reported in some patients with epileptic myoclonic jerks in idiopathic generalized epilepsy and in progressive myoclonic epilepsy. We treated a male patient with posthypoxic nonepileptic myoclonus (Lance-Adams syndrome) with add-on PER and achieved an almost complete cessation of jerks...
2016: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/27408805/nonconvulsive-status-epilepticus-cases-arising-in-connection-with-cephalosporins
#19
Ibrahim Bora, Aylin Bican Demir, Pinar Uzun
Cephalosporins, particularly cefepime, exert neurotoxic side effects that can lead to status epilepticus. These neurotoxic side effects include myoclonus, dystonic movements, tremor, asterixis, seizure, status epilepticus, encephalopathy, and sometimes coma. Status epilepticus, particularly nonconvulsive status epilepticus (NCSE), is a well-known but unusual complication in patients with altered renal function who were receiving treatment with intravenous cephalosporins, especially cefepime. We reviewed the clinical and electroencephalographic (EEG) characteristics of 7 patients with renal failure who developed consciousness alterations with changes in EEG activity while being treated with cephalosporins...
2016: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/27408804/status-epilepticus-caused-by-cerebral-amyloid-angiopathy-related-inflammation
#20
Benjamin Tolchin, Tadeau Fantaneanu, Michael Miller, Jeffrey Helgager, Jong Woo Lee
This report discusses a case of nonconvulsive status epilepticus, caused by cerebral amyloid angiopathy-related inflammation. Brain biopsy demonstrated cerebral amyloid angiopathy, with clinical and radiographic features indicative of a fluctuating inflammatory process. Immunomodulatory treatment with pulse steroids resulted in rapid and dramatic clinical and radiographic improvement. Cerebral amyloid angiopathy-related inflammation should be considered in the differential diagnosis of new-onset seizures after the age of 40, when associated with fluctuating multifocal T2 hyperintensities and petechial hemorrhages on gradient echo (GRE) or susceptibility-weighted (SWI) MRI sequences...
2016: Epilepsy & Behavior Case Reports
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