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Journal of Research in Pharmacy Practice

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https://www.readbyqxmd.com/read/29026847/intralesional-bevacizumab-avastin-%C3%A2-as-a-novel-addition-to-infantile-hemangioma-management-a-medical-hypothesis
#1
Mohsen Pourazizi, Sattar Kabiri, Bahareh Abtahi-Naeini
No abstract text is available yet for this article.
July 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/29026846/intracranial-hemorrhage-in-methanol-toxicity-challenging-the-probable-heparin-effect-during-hemodialysis
#2
Hossein Hassanian-Moghaddam, Hooman Bahrami-Motlagh, Nasim Zamani, Seyed Amirhossein Fazeli, Behdad Behnam
Brain hemorrhages are rare complications of acute methanol poisoning. There is a debate on association of brain hemorrhage in methanol toxicity and application of systemic anticoagulation during hemodialysis (HD). A 70-year-old male presented to us with severe metabolic acidosis and a methanol level of 7.6 mg/dL. Ethanol and folinic acid were administered, and HD was performed. Brain computed tomography (CT) scan which was normal on presentation showed extensive bilateral subcortical supratentorial hypodensities on the 3(rd) day after commencing the treatment...
July 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/29026845/osteonecrosis-of-the-jaws-in-patient-received-bisphosphonates-and-sunitinib-separately-a-case-report
#3
Farzaneh Ashrafi, Ali Derakhshandeh, Bijan Movahedian, Azadeh Moghaddas
Recently published reports have suggested that antiangiogenic drugs such as sunitinib could potentiate the osteonecrosis of the jaw (ONJ) induced by bisphosphonates (BPs) and even induce this adverse effect per se. We reported a case of ONJ with renal cell carcinoma under sunitinib medication and history of BPs therapy. A 53-year-old man was referred to the oral surgery clinic complaining of painful exposed oral lesion and bone extraction from right lower jaw in the mouth. He underwent nephrectomy followed by 5 months treatment with cycles of 50 mg sunitinib (Sutent®) once a day for 4 weeks followed by 2 weeks drug free before lesion exposure in October 2016...
July 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/29026844/an-interprofessional-collaboration-between-medicine-and-pharmacy-schools-designing-and-evaluating-a-teaching-program-on-practical-prescribing
#4
Mohammad Reza Javadi, Mina Khezrian, Anahita Sadeghi, Seyed Hossein Hajimiri, Kaveh Eslami
OBJECTIVE: Medical students need proper education in drug prescription. The aim of the present study is to introduce a course that improves the students' prescribing skills and also promotes an interprofessional collaboration between medicine and pharmacy schools. METHODS: This study was done in a skill laboratory at the pharmacotherapy department of Tehran University of Medical Sciences, Tehran, Iran. The course was an 18-h interactive workshop in 3 days under the supervision of clinical pharmacists...
July 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/29026843/melatonin-supplementation-may-improve-the-outcome-of-patients-with-hemorrhagic-stroke-in-the-intensive-care-unit
#5
Mehrnoush Dianatkhah, Atabak Najafi, Mohammad Sharifzadeh, Arezoo Ahmadi, Hamidreza Sharifnia, Mojtaba Mojtahedzadeh, Farhad Najmeddin, Azadeh Moghaddas
OBJECTIVE: Although mechanical ventilation is frequently a life-saving therapy, its use can result in unwanted side effects. It has been well documented that the choice of sedating agent may influence the duration of mechanical ventilation. Melatonin is a sedative and analgesic agent without any respiratory depressant effect which makes it an attractive adjuvant for sedation in the intubated patients. The aim of this study is to evaluate the effect of melatonin on the duration of mechanical ventilation in patients with hemorrhagic stroke...
July 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/29026842/knowledge-attitude-and-practice-of-iranian-pharmacists-body-builders-and-their-coaches-regarding-sports-supplements
#6
Peivand Bastani, Ali Amjad Nia, Mohammadreza Shabanpoor, Safoora Mehravar, Sara Kashefian
OBJECTIVE: This study is conducted on Iranian pharmacists, coaches, and athletes regarding sports supplements to assess their knowledge, attitude, and practice (KAP) regarding sports supplements. METHODS: This was a cross-sectional study conducted in 2015. The study population consisted of all community pharmacists, bodybuilders, and bodybuilding coaches. The questionnaire was applied consisting some demographic questions and 25 questions for assessing KAP (6, 9, and 10, respectively)...
July 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/29026841/causes-of-medication-errors-in-intensive-care-units-from-the-perspective-of-healthcare-professionals
#7
Sedigheh Farzi, Alireza Irajpour, Mahmoud Saghaei, Hamid Ravaghi
OBJECTIVE: This study was conducted to explore and to describe the causes of medication errors in Intensive Care Units (ICUs) from the perspective of physicians, nurses, and clinical pharmacists. METHODS: The study was conducted using a descriptive qualitative method in 2016. We included 16 ICUs of seven educational hospitals affiliated to Isfahan University of Medical Sciences. Participants included 19 members of the healthcare team (physician, nurse, and clinical pharmacist) with at least 1 year of work experience in the ICUs...
July 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/29026840/impact-of-cyp2c19-polymorphisms-on-serum-concentration-of-voriconazole-in-iranian-hematological-patients
#8
Sholeh Ebrahimpour, Soha Namazi, Mehdi Mohammadi, Mohsen Nikbakht, Molouk Hadjibabaie, Hamidreza Taghvaye Masoumi, Ardeshir Ghavamzadeh
OBJECTIVE: This study aimed to determine the portion of Iranian patients who attain therapeutic serum concentrations of voriconazole (VRCZ) following administration of fixed doses. In addition, the effect of CYP2C19 polymorphism on serum levels of VRCZ was also investigated. METHODS: Forty-eight adult patients of Iranian origin with hematologic malignancies, who received VRCZ for treatment of invasive aspergillosis, were recruited into the study. Blood samples were drawn at day 4 of treatment to measure trough drug concentrations and determine genotyping of CYP2C19 polymorphisms of each patient...
July 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/29026839/missing-the-benefit-of-metformin-in-acute-myeloid-leukemia-a-problem-of-contrast
#9
Alice C Ceacareanu, George K Nimako, Zachary A P Wintrob
OBJECTIVE: To evaluate whether metformin's cancer-related benefits reported in patients with solid tumors (ST) are also present in acute myeloid leukemia (AML) patients. METHODS: Baseline demographic and clinical history for all diabetes mellitus patients newly diagnosed with AML or cancer of the breast, ovary, prostate, gastrointestinal tract, lung, or kidney at Roswell Park Cancer Institute in Buffalo, NY (January 2003-December 2010, n = 924) was collected. Overall survival (OS) and disease-free survival (DFS) were assessed by Kaplan-Meier (KM) analysis and Cox proportional hazards regression (hazard ratio [HR])...
July 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/29026838/tumor-necrosis-factor-alpha-antibodies-in-fistulizing-crohn-s-disease-an-updated-systematic-review-and-meta-analysis
#10
REVIEW
Pardis Zaboli, Mohammad Abdollahi, Shilan Mozaffari, Shekoufeh Nikfar
Medical treatment for fistulizing Crohn's disease (FCD) is changing rapidly over the time by the introduction of novel therapeutic medicines, while no global consensus is available. This study aims to accomplish a systematic review and meta-analysis on the efficacy of tumor necrosis factor-alpha antibodies (anti-TNF-α antibodies) versus placebo in FCD. A systematic review of published literature was carried out till December 2016, and a meta-analysis of identified studies was done. Data have been explored from PubMed, Scopus, Cochrane Library Database, and Web of Science...
July 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/28616439/erratum-a-copmarative-review-of-electronic-prescription-systems-lessons-learned-from-developed-countries
#11
(no author information available yet)
[This corrects the article on p. 3 in vol. 6, PMID: 28331859.].
April 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/28616438/drug-reaction-with-eosinophilia-and-systemic-symptom-in-a-patient-with-pneumonia-and-hyperthyroidism
#12
Hualiang Jin, Limin Wang, Jian Ye
Drug rash with eosinophilia and systemic symptoms syndrome is an idiosyncratic drug reaction characterized by fever, skin eruption, lymph node enlargement, and internal organ involvement. We report a case of a patient with pneumonia who developed clinical manifestations of fever, rash, lymphadenopathy, hypereosinophilia, and visceral involvement (renal failure and eosinophilic pneumonitis) caused by methimazole. The patient improved remarkably with drug withdrawal. A high index of clinical suspicion is emphasized to facilitate prompt diagnosis of medication-related adverse effect and its discontinuation...
April 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/28616437/an-audit-of-perioperative-antimicrobial-prophylaxis-compliance-with-the-international-guidelines
#13
Sarah Mousavi, Elham Zamani, Faranak Bahrami
OBJECTIVE: Antimicrobial prophylaxis has been demonstrated to lower the incidence of postoperative infection in nearly all types of surgery. The American Society of Health-System Pharmacists (ASHP) guideline summarizes current data on the appropriate use of antibiotic for surgical prophylaxis. The objective of this study was to assess and audit the use of antibiotics in a tertiary care center according to the recommendation of ASHP guideline. METHODS: This cross-sectional study was performed using prospective data gathered from April to September 2015 in the surgical wards of Al Zahra Hospital, Isfahan, Iran...
April 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/28616436/initiatives-to-reduce-nonprescription-sales-and-dispensing-of-antibiotics-findings-and-implications
#14
Vanda Marković-Peković, Nataša Grubiša, Johanita Burger, Ljubica Bojanić, Brian Godman
OBJECTIVE: Irrational use of antimicrobials is a major driver of antimicrobial resistance, exacerbated by dispensing antibiotics without a prescription. Our previous study suggested this was a problem in the Republic of Srpska despite legislation. Since then, a number of activities have been initiated. Consequently, the study aimed to ascertain whether these multiple initiatives had reduced this. METHODS: Patients visiting all community pharmacies in the Republic from October 2014 to July 2015 presenting with symptoms typical of an acute, viral, and mostly uncomplicated upper respiratory tract infection, with results compared to the previous study...
April 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/28616435/impact-of-pharmacist-intervention-on-appropriate-insulin-pen-use-in-older-patients-with-type-2-diabetes-mellitus-in-a-rural-area-in-iran
#15
Aida Sefidani Forough, Parsa Riazi Esfahani
OBJECTIVE: The aim of this study was to evaluate the impact of pharmacist-conducted educational intervention on reducing errors related to inappropriate insulin pen use. METHODS: This was a prospective, before-after study with an educational intervention component. The study was conducted on 122 elderly diabetic patients. Data were collected through interviews using researcher-administered questionnaires as well as patients' medical records. Patients were asked about the preparation, injection, and storage techniques, they followed when using insulin pens...
April 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/28616434/developing-an-economic-case-of-clinical-pharmacists-interventions-on-venous-thromboembolism-prophylaxis-through-service-evaluation
#16
Eun Hee Lee, Victoria Bray, Robert Horne
OBJECTIVE: Venous thromboembolism (VTE) has become a huge health problem as well as a financial burden for the National Health Service. The objective of this study was to characterize current practice of VTE prophylaxis (VTEP) and evaluate the economic impact of clinical pharmacists' interventions (CPIs) on VTEP. METHODS: A prospective service evaluation was conducted in a medical and surgical ward at a tertiary teaching hospital in London from 23 May to 08 June 2016...
April 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/28616433/medication-errors-in-patients-with-enteral-feeding-tubes-in-the-intensive-care-unit
#17
Seyed Mojtaba Sohrevardi, Mohammad Hossein Jarahzadeh, Ehsan Mirzaei, Mahtabalsadat Mirjalili, Arefeh Dehghani Tafti, Behrooz Heydari
OBJECTIVE: Most patients admitted to Intensive Care Units (ICU) have problems in using oral medication or ingesting solid forms of drugs. Selecting the most suitable dosage form in such patients is a challenge. The current study was conducted to assess the frequency and types of errors of oral medication administration in patients with enteral feeding tubes or suffering swallowing problems. METHODS: A cross-sectional study was performed in the ICU of Shahid Sadoughi Hospital, Yazd, Iran...
April 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/28616432/effect-of-pretreatment-with-omega-3-supplement-on-cardiac-necrosis-markers-in-chronic-kidney-disease-patients-undergoing-elective-percutaneous-coronary-intervention
#18
Farzaneh Foroughinia, Maryam Foroozmehr
OBJECTIVE: Studies have demonstrated the direct relation between elevation in cardiac necrosis markers and increased risk of cardiovascular complications after percutaneous coronary intervention (PCI) in chronic kidney disease (CKD) patients. In this study, we sought to evaluate the effect of omega-3 on creatine kinase-MB (CK-MB) and troponin-I in CKD patients undergoing elective PCI. METHODS: Eighty CKD patients, candidate for elective PCI, were randomly assigned into two groups: Group A - receiving omega-3 (2...
April 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/28616431/comparing-the-effects-of-zinc-sulfate-calcium-pantothenate-their-combination-and-minoxidil-solution-regimens-on-controlling-hair-loss-in-women-a-randomized-controlled-trial
#19
Mansour Siavash, Fereshteh Tavakoli, Fatemeh Mokhtari
OBJECTIVE: This study was conducted to evaluate the combination of oral supplements with 2% minoxidil solution in four groups of women with hair loss. METHODS: A prospective, randomized controlled trial was conducted from July to December 2016 in dermatology clinics affiliated to Isfahan University of Medical Sciences. A total of 73, 15-45-year-old, women with hair loss participated in this 4-month study. Simple randomization using Random Allocation Software was done to put the participants in four groups to receive coadministration of zinc sulfate and calcium pantothenate, zinc sulfate, calcium pantothenate, and 2% minoxidil solution...
April 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/28616430/training-and-validation-of-standardized-patients-for-assessing-communication-and-counseling-skills-of-pharmacy-students-a-pilot-study
#20
Mahboobeh Khabaz Mafinejad, Mansoor Rastegarpanah, Fereshteh Moosavi, Mandana Shirazi
OBJECTIVE: The objective of this study is to describe the process of training valid simulated patients (SPs) for assessing communication and counseling skills of pharmacy students' performance. METHODS: This is a cross-sectional and correlational study. Psychometric properties of checklist and SPs' portrayals and their filling of the checklist regarding assessing pharmacy students were assessed. Five SPs who were working in the simulated patient's pool were volunteered to take part in the project, which one of the SPs failed...
April 2017: Journal of Research in Pharmacy Practice
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