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Journal of Research in Pharmacy Practice

Gholamali Dorooshi, Shafeajafar Zoofaghari, Nastaran Eizadi Mood, Farzad Gheshlaghi
No abstract text is available yet for this article.
July 2018: Journal of Research in Pharmacy Practice
Alireza Dehghani, Mohammad-Hasan Alemzadeh-Ansari, Marjan Masjedi, Arman Amirkhani, Mohsen Pourazizi
Erectile dysfunction (ED) has negative effects on quality of life. The first line of oral medication for this condition is phosphodiesterase type 5 inhibitors (PDE5I) including Tadalafil. Ocular complications associated with Tadalafil are rare and usually occurred in participant with known risk factors. In this report, we describe and review the related literature of development of nonarteritic anterior ischemic optic neuropathy -associated Tadalafil. A healthy nonsmoking 42-year-old male with a history of ED presented with acute onset of an inferior visual field defect on the right eye...
July 2018: Journal of Research in Pharmacy Practice
Maryam Farasatinasab, Atefeh Amouzegar, Saeed Safari, Behrooz Ghanbari, Majid Darkahian, Sepideh Emami, Nashmin Pakdaman, Maryam Salili
Objective: Human albumin solution is an expensive colloidal preparation which is commonly used in clinical practice. Due to high cost of albumin, increased rate of the inappropriate use worldwide, and many other reasons, it is imperative to establish a practical protocol to use albumin products and limit its usage. The aim of this study was to identify albumin utilization patterns in a teaching hospital and to demonstrate the importance of the need to reconsider prescribing strategies for albumin administration...
July 2018: Journal of Research in Pharmacy Practice
Fatemeh Karimi, Farzaneh Ashrafi, Azadeh Moghaddas, Ali Derakhshandeh
Objective: Febrile neutropenia (FN) is one of the most serious clinical problems in patients with hematologic malignancies and patients receiving chemotherapy. The present study was implemented to determine precisely how FN is managed in most referral hospitals in Isfahan (Iran) and what are the characteristics of FN patients as well as risk factors associated with FN development. Methods: This study was a cross-sectional study performed over a period of 6 months on patients hospitalized in the Hematology-Oncology Center of Omid Hospital, Isfahan, Iran...
July 2018: Journal of Research in Pharmacy Practice
Anahita Arian, Sayyed Gholamreza Mortazavi Moghadam, Tooba Kazemi, Mahmood Zardast, Asghar Zarban
Objective: The present study was designed to investigate the effects of atorvastatin on serum high-sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL-6), total antioxidant capacity (TAC), and alpha-1 antitrypsin (AAT) in patients with chronic obstructive pulmonary disease (COPD). Methods: A clinical trial study conducted on 42 cases of COPD (Vali-Asr Hospital, Birjand, East of Iran, years 2014-16). Patients were randomly assigned to 21 controls and 21 cases who treated with atorvastatin (40 mg/day for 6 months)...
July 2018: Journal of Research in Pharmacy Practice
Nastaran Eizadi-Mood, Raana Ahmadi, Sara Babazadeh, Ahmad Yaraghi, Massoumeh Sadeghi, Payam Peymani, Ali Mohammad Sabzghabaee
Objective: Suicide is a social health problem worldwide. Anemia has been associated with depression. Since it remains debated whether anemia is associated with suicide independently of depression, we evaluate this probable association in women who attempted suicide through acute poisoning. Methods: The study design was cross-sectional and performed on women who attempted suicide through intentional poisoning with age more than 18 years old. Different variables were evaluated and compared in patients with respect to anemia, depression, other psychiatric diseases and history of suicide...
July 2018: Journal of Research in Pharmacy Practice
Ebrahim Khadem, Mahboobeh Shirazi, Leila Janani, Roja Rahimi, Parastoo Amiri, Fereshteh Ghorat
Objective: Postoperative ileus (POI) is a common complication after surgery that requires a multifactorial therapeutic approach. This study aims to assess the effect of topical chamomile oil on postoperative bowel activity after cesarian section. Methods: This randomized controlled trial was carried out in 2015 at Chamran Hospital in Iran. A block randomization list was generated for 142 parturient divided into three groups. In the intervention group (arm A) ( n = 47), chamomile oil was applied topically on abdominal region after the stability of the patient...
July 2018: Journal of Research in Pharmacy Practice
Ehsanallah Jafari, Maryam Moeeni, Reza Fadaei, Reza Rezayatmand
Objective: Pesticides have been used as the main part of the national cutaneous leishmaniasis control program for serveral years in Iran. However, the cost-effectiveness of this strategy has not been yet analyzed. The aim of this study is to to analyze the cost-effectiveness and cost-utility of using pesticides as the main strategy to prevent rural CL in Isfahan. Methods: This is an economic evaluation study performed from a health system perspective to estimate the cost-effectiveness and cost-utility of the control strategy with and without pesticides...
July 2018: Journal of Research in Pharmacy Practice
Soheil Roshanzamiri, Kaveh Eslami, Farhad Najmeddin, Mandana Izadpanah, Elham Hadidi, Reza Ganji
Objective: Medication Therapy Management service (MTMs) has been introduced to improve cooperation among pharmacists and other healthcare professionals in the management of chronic diseases, drug therapy, and patients on polypharmacy. One part of MTMs is detection and resolution of possible drug-related problems (DRPs). Nowadays, numerous DRPs classification systems are available, but due to some defects none of them are currently accepted and implemented universally. The purpose of this study is to design and validate a comprehensive system for classification and documentation of possible DRPs for the Iranian patients...
July 2018: Journal of Research in Pharmacy Practice
Gholamali Dorooshi, Shafeajafar Zolfaghari, Nastaran Eizadi-Mood, Farzad Gheshlaghi
No abstract text is available yet for this article.
April 2018: Journal of Research in Pharmacy Practice
Srija Gopal, Selvalaxmi Gnanasegaran, Gerard Marshall Raj, Sakthibalan Murugesan, Mangaiarkkarasi Adhimoolam
Cetirizine, a piperazine-derivative second-generation antihistaminic, is used for a wide variety of disorders such as urticaria, eczema, and allergies. Adverse reactions due to this drug are usually rare, especially fixed drug eruption (FDE), a delayed cell-mediated hypersensitivity reaction, is scarce. Here, we report a case of cetirizine-induced FDE. A 34-year-old female developed hyperpigmented, itchy patches over both forearms, legs, feet, and right side of the chest after taking tablet cetirizine for dry cough with similar episode 2 years back on the same sites...
April 2018: Journal of Research in Pharmacy Practice
Vajihe Atashi, Ahmadreza Yazdannik, Hosein Mahjobipoor, Somayeh Ghafari, Reza Bekhradi, Hojatollah Yousefi
Objective: Mouth dryness is one of the most prevalent problems in Intensive Care Units (ICUs). It facilitates dental plaque formation. The aim of this study was to analyze the effects of Aloe vera -Peppermint (Veramin) moisturizing gel on mouth dryness and oral health among patients hospitalized in ICUs. Methods: This triple-blind two-group randomized placebo-controlled clinical trial was undertaken in 2016-2017 on a convenient sample of 80 patients. Patients were randomly allocated to an intervention and a placebo group...
April 2018: Journal of Research in Pharmacy Practice
Alireza Yektadoost, Farid Ebrahimi, Mohammadreza Mashouf, Naghmeh Hadidi, Nasser Nassiri Koopaei, Abbas Kebriaeezadeh
Objective: Iranian healthcare system cost has been remarkably growing during the recent decades. Drug shortages and the economic effects of the sanctions have also exposed the pitfalls and shortcomings of the pharmaceutical system. Moreover, the pharmaceutical system is a major expenditure source for the health system. Pharmaceutical market trend analysis serves as a reliable tool to gather and analyze market and consumption data to take account of the past policies and forecast the future of the market and disease trends...
April 2018: Journal of Research in Pharmacy Practice
Michael J Cawley, William J Warning
Objective: This study was designed to describe the impact of a trained pharmacist in performing quality spirometry testing within a community family health center. Methods: This was a retrospective, cohort study of 150 physician-referred patients who attended their scheduled spirometry office appointment between November 2008 and December 2013. Information obtained included type of the disease (patients with obstructive or restrictive pulmonary disease), calculated lung age decline due to smoking history, quality of spirometry testing, and percentage of patients requiring pulmonary drug regimen alterations due to spirometry results...
April 2018: Journal of Research in Pharmacy Practice
Peyman Naderi, Kiana Shirani, Rasool Soltani, Farzin Khorvash, Seyed Saeed Naji Esfahani
Objective: Inappropriate use of antibiotics is associated with detrimental effects including emergence of antibiotic resistance. This study aimed to evaluate the use of meropenem, an extended-spectrum antibiotic, in a referral teaching hospital to detect different types of errors in its prescription. Methods: In a cross-sectional study performed over a 6-month period (2014-2015), hospitalized adult patients who received meropenem for any indication were randomly selected...
April 2018: Journal of Research in Pharmacy Practice
Mwasi Mary Ann Mukokinya, Sylvia Opanga, Margaret Oluka, Brian Godman
Objective: The objective of this study was to evaluate the extent of self-medication of antibiotics and dispensing practices in Kenya. Methods: A cross-sectional study was carried out at three selected pharmacies in Nairobi (Kenya), between January and March 2017, targeting principally antibiotic prescriptions for systemic use issued and dispensed as well as antibiotics sold over-the-counter without a prescription. The quality of antibiotics prescribed and dispensed was assessed against key WHO and other criteria...
April 2018: Journal of Research in Pharmacy Practice
Maryam Ghadimi, Simin Dashti-Khavidaki, Mohammad-Reza Khatami, Mitra Mahdavi-Mazdeh, Mansoor Gatmiri, Farzaneh Sadat Minoo, Neda Naderi, Atefeh Jafari, Mohammad-Reza Abbasi, Ali Ghafari
Objective: Delayed graft function (DGF) is an early complication after kidney transplantation with negative impact on allograft outcomes. This study assessed the effect of delayed initiation of tacrolimus as a nephrotoxic drug, on DGF occurrence and allograft function. Methods: This randomized, open-label clinical trial was conducted on kidney transplant recipients with the age of at least 14 years who underwent the first kidney transplantation from deceased or living donor...
April 2018: Journal of Research in Pharmacy Practice
Tahereh Gholipur-Shahraki, Awat Feizi, Mojgan Mortazavi, Shirinsadat Badri
Protein energy malnutrition is a common problem in patients with chronic kidney disease (CKD). Scattered reports indicate that supplementation of Carnitine may improve patients' clinical symptoms, with significant improvement in nutritional parameters. This systematic review was done to document the evidences of Carnitine effects in nutritional status of CKD patients. Peer-reviewed RCTs on Carnitine administration at any dose in CKD patients with at least four weeks of follow-up were including in the meta-analysis...
April 2018: Journal of Research in Pharmacy Practice
Seyed Amirhossein Fazeli, Morteza Abbasi, Hadi Jalali, Sonia Eskandari, Farzaneh Shamshirgaran, Zahra Dehghani, Reza Golabchifard, Shahram Ghiyasvand, Kaveh Ghannad
Fixed drug eruption (FDE) is a drug reaction involving skin and less commonly mucosal membranes. The common manifestation is localized well-demarcated patches or plaques appeared following receiving of a culprit drug. When re-exposure occurs, the rashes will appear at areas involved in previous episodes. Limited reports on bullous FDE due to ibuprofen have been documented before. Herein, we described an elderly man who experienced multifocal lesions in his oral mucosa, penis, and multiple sites of skin following ibuprofen ingestion confirmed as FDE by pathological studies...
January 2018: Journal of Research in Pharmacy Practice
Maryam Taghizadeh-Ghehi, Asiyeh Amouei, Ava Mansouri, Aarefeh Jafarzadeh Kohneloo, Molouk Hadjibabaie
Objective: Cancer is a global health concern with growing incidence worldwide. Chemotherapy is the main treatment modality in many malignancies. This study aimed at evaluation of antineoplastic prescribing pattern and prescription-writing quality in the capital city of Iran. Methods: All dispensed chemotherapy prescriptions by four main authorized pharmacies in Tehran during 1 month were targeted. Prescriptions with no antineoplastic medications or written by specialties other than oncology-related fields were excluded from the study...
January 2018: Journal of Research in Pharmacy Practice
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