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Avicenna Journal of Phytomedicine

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https://www.readbyqxmd.com/read/27761428/effects-of-flavonoids-from-martynia-annua-and-tephrosia-purpurea-on-cutaneous-wound-healing
#1
Santram Lodhi, Avijeet Jain, Alok Pal Jain, Rajesh Singh Pawar, Abhay Kumar Singhai
OBJECTIVE: Martynia annua L. (M. annua), (Martyniaccae) has been traditionally used in the treatment of epilepsy, sore throat and inflammatory disorders. The leaf paste is used topically on Tuberculosis of the lymphatic glands and wounds of domestic animals. Tephrosia purpurea (T. purpurea), (Fabaceae) has been used traditionally as a remedy for asthma, gonorrhea, rheumatism and ulcers. This study aimed to evaluate the potential wound healing effects of different fractions ofethanol extract of M...
September 2016: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/27761427/the-effect-of-nano-curcumin-on-hba1c-fasting-blood-glucose-and-lipid-profile-in-diabetic-subjects-a-randomized-clinical-trial
#2
Hamid Reza Rahimi, Amir Hooshang Mohammadpour, Mostafa Dastani, Mahmoud Reza Jaafari, Khalil Abnous, Majid Ghayour Mobarhan, Reza Kazemi Oskuee
OBJECTIVE: Diabetes mellitus is defined as a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both or insulin resistance. Curcumin inhibits NF-κB signaling pathway. The aim of this study is evaluation of the effect of Nano-curcumin on HbA1C, fast blood glucose and lipid profile in diabetic patients. MATERIALS AND METHODS: Seventy type-2 diabetic patients (fasting blood glucose (FBG) ≥ 126 mg/dL or 2-hr postprandial blood glucose ≥200 mg/dl) randomly receivedeither Curcumin (as nano-micelle 80 mg/day) or placebo for 3 months in a double blind randomized clinical trial...
September 2016: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/27761426/evaluation-of-acute-and-sub-acute-toxicity-of-pinus-eldarica-bark-extract-in-wistar-rats
#3
Akram Ghadirkhomi, Leila Safaeian, Behzad Zolfaghari, Mohammad Reza Agha Ghazvini, Parisa Rezaei
OBJECTIVE: Pinus eldarica (P. eldarica) is one of the most common pines in Iran which has various bioactive constituents and different uses in traditional medicine. Since there is no documented evidence for P. eldarica safety, the acute and sub-acute oral toxicities of hydroalcoholic extract of P. eldarica bark were investigated in male and female Wistar rats in this study. MATERIALS AND METHODS: In the acute study, a single dose of extract (2000 mg/kg) was orally administered and animals were monitored for 7 days...
September 2016: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/27761425/comparison-of-antiplatelet-activity-of-garlic-tablets-with-cardio-protective-dose-of-aspirin-in-healthy-volunteers-a-randomized-clinical-trial
#4
Mojtaba Shafiekhani, Pouya Faridi, Javad Kojuri, Soha Namazi
OBJECTIVE: Some of the adverse effects of aspirin including peptic ulcers, gastrointestinal bleeding and aspirin resistance compelled researchers to find a suitable alternative with fewer adverse effects. In this clinical trial, we aimed to find the effective antiplatelet dose of garlic. MATERIALS AND METHODS: This randomized controlled clinical trial (RCT) was conducted on 62 healthy volunteers of 20-50 years old. All volunteers used 80 mg aspirin per day for 1 week and at the end of this time, platelet aggregation (PA) induced by 4 agonists acting in aggregation pathway including adenosinediphosphate (20 μmol/l), epinephrine (20 μmol/l), collagen(0...
September 2016: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/27761424/teratogenic-effects-of-silymarin-on-mouse-fetuses
#5
Mahbobe Gholami, Seyed Adel Moallem, Mohammad Afshar, Sakineh Amoueian, Leila Etemad, Gholamreza Karimi
OBJECTIVE: Silybum marianum has been used for centuries in herbal medicine for treatment of liver diseases. Currently, there is no data available on the possible effects of silymarin on fetal development. This study aimed to investigate the teratogenic effect of silymarin on BALB/c mice fetuses. MATERIALS AND METHODS: A total of 40 pregnant mice were divided into 4 groups of 10 mice each. Three groups received silymarin at three different doses of 50, 100 and 200 mg/kg/day during gestational days (GDs)...
September 2016: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/27761423/effect-of-virgin-olive-oil-versus-piroxicam-phonophoresis-on-exercise-induced-anterior-knee-pain
#6
Babak Nakhostin-Roohi, Faegheh Khoshkhahesh, Shahab Bohlooli
OBJECTIVE: The main purpose of this study was to evaluate the effects of virgin olive oil phonophoresis on female athletes' anterior knee pain (AKP). MATERIALS AND METHODS: A double blinded randomized clinical trial was conducted. Ninety-three female athletes suffering from AKP voluntarily participated in this study. Patients were randomly assigned into olive oil (n=31), piroxicam (n=31) or base gel phonophoresis (n=31) groups. At the baseline visit, the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire was filled by subjects who were then treated with olive oil, piroxicam or pure phonophoresis for 12 sessions...
September 2016: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/27761422/estragole-and-methyl-eugenol-free-extract-of-artemisia-dracunculus-possesses-immunomodulatory-effects
#7
Seyyed Meysam Abtahi Froushani, Leila Zarei, Hadi Esmaeili Gouvarchin Ghaleh, Bahman Mansori Motlagh
OBJECTIVE: Some evidence suggests that chronic uptake of estragole and methyl-eugenol, found in the essential oil of Artemisia dracunculus (tarragon), may be associated with an increased risk of hepato-carcinogenicity. The present study was conducted to investigate the immumodulatory and anti-inflammatory potentials of estragole and methyl-eugenol free extract of tarragon. MATERIALS AND METHODS: Aqueous, hydroalcoholic, methanol and hexane extracts of dried and milled tarragon was prepared and analyzed by GC-MS...
September 2016: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/27761421/anti-oxidant-and-anti-hyperlipidemic-activity-of-hemidesmus-indicus-in-rats-fed-with-high-fat-diet
#8
Suganya Venkateshan, Vetriselvan Subramaniyan, Velmurugan Chinnasamy, Sarath Chandiran
OBJECTIVE: Dietary changes play major risk roles in oxidative stress and cardiovascular disease and modulate normal metabolic function. The present study was designed to investigate the ameliorative potential of different extracts of Hemidesmus indicus to experimental high-fat diet in wistar rats, and their possible mechanism of action. MATERIALS AND METHODS: Male wistar rats were divided into 6 groups (n=6/group) and fed with a standard diet (control), high-fat diet (HFD), high-fat diet supplemented with different extracts and positive control for 9 weeks...
September 2016: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/27761420/a-review-study-on-the-effect-of-iranian-herbal-medicines-against-in-vitro-replication-of-herpes-simplex-virus
#9
Mohammad-Taghi Moradi, Mahmoud Rafieian-Kopaei, Ali Karimi
OBJECTIVE: There are a number of published data indicating in vitro anti-HSV activity of some of Iranian herbal extracts with no systematic review to discuss these results. Therefore, this article was aimed to review and discuss the methods carried out and the phytochemistry and bioactivity of the extracts used and also conclusions provided in these publications. MATERIALS AND METHODS: Published articles both in English (from Medline, Science Direct, EMBASE, Scopus, Pro Quest, Google scholar, Cochrane Library) and in Persian (from SID, Iran Medex and Magiran) databases, from 1966 to October 2014 were incorporated in this review...
September 2016: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/27761419/urological-recommedations-of-hadji-pasha-s-a-turkish-aged-doctor-in-anatolia
#10
Mehmet Erol Yıldırım, Metin Canbal, Ekrem Ozyuvali, Ömer Faruk Karataş
OBJECTIVE: Urinary tract conditions have been an important part of diseases from antiquity until today. Historically, many plants and herbs have been used for the treatment of urinary disorders. METHODS: Celâlüddîn Hızır bin Ali el-Konevi (Hadji Pasha) is one of the most famous physician who lived in Anatolia between 13th and 14th centuries. He has written one of the most important medical books of that era, "Müntehab-ıŞifa" (solution of wellness) in Turkish...
September 2016: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/27761418/assessment-of-antibacterial-effect-of-garlic-in-patients-infected-with-helicobacter-pylori-using-urease-breath-test
#11
Mahmoud Zardast, Kokab Namakin, Jamil Esmaelian Kaho, Sarira Sadat Hashemi
OBJECTIVE: Helicobacter pylori (H. pylori) is the most common pathogenic bacteria in the stomach. The aim of the current study was to explore the effect of oral garlic administration on bacterial urease activity inside the stomach and its contribution to the treatment of H. pylori infection. MATERIALS AND METHODS: In this clinical trial, 15 patients were studied quantitatively with Urease Breath Test (UBT). The patients with gastrointestinal symptoms and a positive serum H...
September 2016: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/27761417/capparis-spinosa-reduces-doxorubicin-induced-cardio-toxicity-in-cardiomyoblast-cells
#12
Seyed Hadi Mousavi, Azar Hosseini, Elham Bakhtiari, Hassan Rakhshandeh
OBJECTIVE: Doxorubicin (DOX) is an effective anticancer drug but its clinical application is limited because it induces apoptosis in cardiomyocytes and leads to permanent degenerative cardiomyopathy and heart failure possibly due to oxidative stress. Recent studies showed that Capparis spinosa (C. spinose) exhibits potent antioxidant activity. So, in this study, we explored the protective effect of hydro-alcoholic extract of C. spinosa against DOX-induced cytotoxicity in H9c2 cells. MATERIALS AND METHODS: Cell viability was quantified by MTT assay...
September 2016: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/27516989/anxiolytic-like-effect-of-ethanolic-extract-of-argemone-mexicana-and-its-alkaloids-in-wistar-rats
#13
Aideé Itzel Arcos-Martínez, Omar David Muñoz-Muñiz, Miguel Ángel Domínguez-Ortiz, Margarita Virginia Saavedra-Vélez, Maribel Vázquez-Hernández, María Gabriela Alcántara-López
OBJECTIVE: Argemone mexicana is a Papaveracea plant; some reports have shown their antibacterial, anti-cancer, sedative and probably anti-anxiety properties. From their aerial parts, flavonoids and alkaloids have been isolated, which are intrinsically related to some actions on the central nervous system. The aim of this study was to evaluate the anxiolytic-like effects of the plant, using its ethanolic extract and alkaloid-enriched extract obtained from fresh leaves. MATERIAL AND METHODS: Phytochemical screening was carried out together with evaluation of antioxidant capacity and the enrichment of alkaloids present in the extract...
July 2016: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/27516988/therapeutic-effect-of-frankincense-in-a-rat-model-of-alzheimer-s-disease
#14
Siamak Beheshti, Rezvan Aghaie
OBJECTIVE: Frankincense improves memory in different models of learning. However, its influence on models of Alzheimer's disease (AD) has not been studied widely. In the present study, the therapeutic effect of frankincense was evaluated in a model of AD induced by i.c.v administration of streptozotocin. MATERIALS AND METHODS: Under stereotaxic surgery, two guide cannulas were implanted in the lateral ventricles of adult male Wistar rats weighing 230-270 g. One group received streptozotocin (1...
July 2016: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/27516987/the-effect-of-allium-sativum-garlic-extract-on-infectious-bronchitis-virus-in-specific-pathogen-free-embryonic-egg
#15
Tabassom Mohajer Shojai, Arash Ghalyanchi Langeroudi, Vahid Karimi, Abbas Barin, Naser Sadri
OBJECTIVE: Garlic is a plant has been used as a flavor, and anti-microbial and anti-diarrheal agent. Infectious bronchitis virus (IBV) is a coronavirus. The available vaccines against IBV cannot cover new variants. This study evaluated the inhibitory effects of garlic extract on IBV. MATERIALS AND METHODS: The constituents of garlic extract were detected by gas chromatography. This study was done in four groups of embryonic SPF eggs; first group was used for virus titration; second group received the mixture of different virus titration and constant amount of garlic extract; third group received 10(-3) titration of virus and after 8 hr received garlic extract and the last group received different dilutions of garlic extract...
July 2016: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/27516986/hydroalcoholic-extract-of-needles-of-pinus-eldarica-enhances-pentobarbital-induced-sleep-possible-involvement-of-gabaergic-system
#16
Fatemeh Forouzanfar, Ahmad Ghorbani, Mahmoud Hosseini, Hassan Rakhshandeh
OBJECTIVE: Insomnia is accompanied by several health complications and the currently used soporific drugs can induce several side effects such as psychomotor impairment, amnesia, and tolerance. The present study was planned to investigate the sleep prolonging effect of Pinus eldarica. MATERIALS AND METHODS: Hydroalcoholic extract (HAE) of P. eldarica, its water fraction (WF), ethyl acetate fraction (EAF) and n-butanol fraction (NBF) were injected (intraperitoneally) to mice 30 min before administration of pentobarbital...
July 2016: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/27516985/the-effects-of-crocin-and-safranal-on-the-yawning-induced-by-intracerebroventricular-injection-of-histamine-in-rats
#17
Mina Taati, Esmaeal Tamaddonfard, Amir Erfanparast, Hamid Ghasemi
OBJECTIVE: Crocin and safranal, as the major constituents of saffron, have many biological activities. This study investigated the effects of crocin and safranal on yawning response induced by intracerebroventricular (i.c.v.) injection of histamine in rats. MATERIALS AND METHODS: In ketamine/xylazine-anesthetized rats, a guide cannula was implanted in the right ventricle of the brain and yawning induced by i.c.v. injection of histamine. Crocin and safranal were intraperitoneally (i...
July 2016: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/27516984/protective-effect-of-viola-tricolor-and-viola-odorata-extracts-on-serum-glucose-deprivation-induced-neurotoxicity-role-of-reactive-oxygen-species
#18
Seyed Hadi Mousavi, Behnaz Naghizade, Solmaz Pourgonabadi, Ahmad Ghorbani
OBJECTIVE: Oxidative stress plays a key role in the pathophysiology of brain ischemia and neurodegenerative disorders. Previous studies indicated that Viola tricolor and Viola odorata are rich sources of antioxidants. This study aimed to determine whether these plants protect neurons against serum/glucose deprivation (SGD)-induced cell death in an in vitro model of ischemia and neurodegeneration. METHODS AND MATERIAL: The PC12 neuronal cells were pretreated for 4 hr with 1 to 50 µg/ml of V...
July 2016: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/27516983/phytochemical-screening-and-evaluation-of-antioxidant-activities-of-dracocephalum-kotschyi-and-determination-of-its-luteolin-content
#19
Mansureh Kamali, Susan Khosroyar, Hossein Kamali, Tooba Ahmadzadeh Sani, Ameneh Mohammadi
OBJECTIVE: Dracocephalum kotschyi (Lamiaceae family) has been used in traditional medicine for stomach and liver disorders, headache and congestion. In the present study, we have investigated phytochemical properties and antioxidant activities of dichloromethane, ethyl acetate and methanol extracts of D.kotschyi. MATERIAL AND METHODS: Antioxidant activities of extracts were evaluated using the integration of HPLC-DPPH and ferric reducing antioxidant power (FRAP) methods...
July 2016: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/27516982/effects-of-persian-leek-allium-ampeloprasum-on-hepatic-lipids-and-the-expression-of-proinflammatory-gene-in-hamsters-fed-a-high-fat-high-cholesterol-diet
#20
Vahideh Fatoorechi, Marjan Rismanchi, Javad Nasrollahzadeh
OBJECTIVE: Persian leek is one of the most widely used herbal foods among Iranians. In this study, effects of oral administration of Persian leek on plasma and liver lipids were examined in hamster. MATERIALS AND METHODS: Male Syrian hamsters were randomly divided into three groups: control (standard diet), high fat control (high-fat/high-cholesterol diet), Persian leek (high-fat/high-cholesterol diet + 1% per weight of diet from dried powdered Persian leek) for 14 weeks...
July 2016: Avicenna Journal of Phytomedicine
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