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Asia-Pacific Journal of Ophthalmology

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https://www.readbyqxmd.com/read/28906084/updates-on-the-epidemiology-of-age-related-macular-degeneration
#1
Jost B Jonas, Chui Ming Gemmy Cheung, Songhomitra Panda-Jonas
This meta-analysis reports on current estimates of the prevalence of age-related macular degeneration (AMD) based on a review of recent meta-analyses and literature research. Within an age of 45-85 years, global prevalences of any AMD, early AMD, and late AMD were 8.7% [95% credible interval (CrI), 4.3‒17.4], 8.0% (95% CrI, 4.0‒15.5), and 0.4% (95% CrI, 0.2-0.8). Early AMD was more common in individuals of European ancestry (11.2%) than in Asians (6.8%), whereas prevalence of late AMD did not differ significantly...
September 14, 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28905541/the-role-of-new-imaging-methods-in-managing-age-related-macular-degeneration
#2
Stephen James Talks, Akhunzada Muhammad Aftab, Imran Ashfaq, Taha Soomro
The use of imaging for age-related macular degeneration (AMD) depends on how it benefits clinical management and on reimbursement. The latter should relate to the former. This review assesses how different forms of AMD can be imaged and what information this provides. For nonneovascular AMD high-resolution optical coherence tomography (OCT), autofluorescence, and near infrared imaging can identify the type of drusen, such as reticular pseudodrusen, which influences prognosis, and the amount of atrophy, for which phase 3 trials are underway...
September 14, 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28905540/nanosecond-laser-cataract-surgery-in-locs-iii-grade-4-and-5-a-case-series
#3
Gangolf Sauder, Elena Ruf, Sarah Moedl, Reinhardt Thyzel
PURPOSE: A major obstacle to the widespread implementation of nanosecond laser cataract removal has been its limited efficacy in cases when the cataract is harder than Lens Opacities Classification System III (LOCS III) grade 3. The latest technological modifications seem to have overcome this obstacle. DESIGN: A case series. METHODS: This study presents a case series of 17 consecutive patients with a cataract classified as harder than LOCS III grade 3 who underwent nanolaser cataract surgery...
September 14, 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28905539/new-treatment-modalities-for-geographic-atrophy
#4
Rathika Kandasamy, Sanjeewa Wickremasinghe, Robyn Guymer
Age-related macular degeneration (AMD) is a significant cause of global visual morbidity and is projected to affect 288 million people by the year 2040. The advent of treatment with anti‒vascular endothelial growth factor (anti-VEGF) drugs has revolutionized the treatment of neovascular AMD (nAMD) but there have been no similar breakthroughs for the treatment of geographic atrophy (GA) to retard its progression. The advancements in imaging and new understanding of disease mechanisms, based on molecular and genetic models, have paved the way for the development of novel experimental treatment options for GA that aim to cater to a thus far largely unmet need...
September 14, 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28868833/evaluation-of-interleukin-17-and-interleukin-23-in-pterygium-immunohistochemistry-study
#5
Kiew Ing Tiong, Aida Zairani Mohd Zahidin, S Kala A/P Sumugam, Joseph Uchang, Hazlita Dato' Mohd Isa
PURPOSE: To compare the interleukin-17 (IL-17) and interleukin-23 (IL-23) positive cell counts between pterygium and normal conjunctiva. DESIGN: A case-control study. METHODS: This study received ethical approval (NMRR Research ID 23957) and informed consent was obtained from all participants. It involved 20 participants with 20 samples of pterygium and 20 samples of normal conjunctiva that were obtained from the same eye of each participant...
September 4, 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28868832/combined-cataract-extraction-with-pars-plana-vitrectomy-and-metallic-intraocular-foreign-body-removal-through-sclerocorneal-tunnel-using-a-novel-magnet-handshake-technique
#6
Pankaja Dhoble, Ashish Khodifad
PURPOSE: To study the outcomes of combined cataract extraction with pars plana vitrectomy (PPV) and metallic intraocular foreign body (IOFB) removal through a sclerocorneal tunnel using the "magnetic handshake" technique. DESIGN: A retrospective review. METHODS: Retrospective review of case records of 14 patients from 2010 to 2016 with metallic IOFB and traumatic cataract was performed. Cataract extraction was combined with PPV. Two intraocular magnets (IOMs) introduced through 20-gauge vitrectomy port and sclerocorneal tunnel helped achieve safe delivery of IOFB outside the globe by the "magnetic handshake" technique...
September 4, 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28829109/adult-orbital-and-adnexal-xanthogranulomatous-disease
#7
Michael J Davies, Kevin Whitehead, Gary Quagliotto, Dominic Wood, Rajan S Patheja, Timothy J Sullivan
PURPOSE: Adult xanthogranulomatous disease of the orbit and ocular adnexa is a rare disease that can cause serious morbidity and mortality. Ophthalmologists are commonly the first clinicians to come in contact with affected patients and an understanding of the clinical features is essential. DESIGN: We present a retrospective case series of patients seen in the oculoplastic unit of a large tertiary referral hospital over a 20-year period. METHODS: The clinical files of 7 patients with adult xanthogranulomatous disease of the orbit and ocular adnexa were reviewed...
August 22, 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28828764/randomized-controlled-trial-of-topical-insulin-for-healing-corneal-epithelial-defects-induced-during-vitreoretinal-surgery-in-diabetics
#8
Seng Fai, Amin Ahem, Mushawiathi Mustapha, Umi Kalthum Mohd Noh, Mae-Lynn Catherine Bastion
PURPOSE: To determine the effect of topical insulin of 3 concentrations [0.5, 1, and 2 units per drop 4 times per day (QID)] on postoperative corneal epithelial wound healing in diabetic patients. DESIGN: A double blind randomized controlled hospital-based study involving diabetic patients with postoperative corneal epithelial defect after vitreoretinal surgery. METHODS: Diabetic patients were randomized to 3 different concentrations of topical insulin (DTI 0...
August 22, 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28828763/laser-and-anti-vascular-endothelial-growth-factor-agent-treatments-for-retinal-arterial-macroaneurysm
#9
Yen-Yi Chen, Lo-Yi Lin, Pei-Yao Chang, Fang-Ting Chen, Elsa L C Mai, Jia-Kang Wang
PURPOSE: To describe the efficacy of laser and intravitreal injection of anti-vascular endothelial growth factor (anti-VEGF) agents for patients with symptomatic retinal arterial macroaneurysm (RAM). DESIGN: From 2009 to 2016, we collected patients with exudative or hemorrhagic RAM all treated by focal laser photocoagulation. METHODS: Nd:YAG laser was performed in patients with subinternal limiting membrane (sub-ILM) hemorrhage. Intravitreal anti-VEGF agents were given in eyes with macular exudation as adjuncts...
August 22, 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28780779/femtosecond-lasers-and-corneal-surgical-procedures
#10
Gustavo K Marino, Marcony R Santhiago, Steven E Wilson
Our purpose is to present a broad review about the principles, early history, evolution, applications, and complications of femtosecond lasers used in refractive and nonrefractive corneal surgical procedures. Femtosecond laser technology added not only safety, precision, and reproducibility to established corneal surgical procedures such as laser in situ keratomileusis (LASIK) and astigmatic keratotomy, but it also introduced new promising concepts such as the intrastromal lenticule procedures with refractive lenticule extraction (ReLEx)...
July 31, 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28657286/personality-and-total-health-through-life-project-eye-substudy-methodology-and-baseline-retinal-features
#11
Peter van Wijngaarden, Stuart Keel, Lauren A B Hodgson, Dinesh K Kumar, Behzad Aliahmad, Cistiane C Paim, Kim M Kiely, Nicolas Cherbuin, Kaarin J Anstey, Mohamed Dirani
PURPOSE: To describe the methodology and present the retinal grading findings of an older sample of Australians with well-defined indices of neurocognitive function in the Personality and Total Health (PATH) Through Life project. DESIGN: A cross-sectional study. METHODS: Three hundred twenty-six individuals from the PATH Through Life project were invited to participate. Participants completed a general questionnaire and 2-field, 45-degree nonmydriatic color digital retinal photography...
June 27, 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28780782/endophthalmitis-prophylaxis-for-cataract-surgery
#12
Aravind Haripriya, Zervin R Baam, David F Chang
Endophthalmitis after cataract surgery is a rare but potentially devastating complication. There is great variability in endophthalmitis prophylaxis practice patterns worldwide. Treatment varies globally and is based on the microbiological profile and availability of formulations. Periocular povidone-iodine antisepsis is universally adopted and considered the standard of care in most practices. Perioperative topical antibiotics are also very popular despite the lack of level 1 evidence confirming efficacy. Based on growing observational evidence, routine intracameral antibiotic prophylaxis is increasing, especially where approved commercial intraocular preparations are available...
July 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28780781/multifocal-intraocular-lenses-and-extended-depth-of-focus-intraocular-lenses
#13
Detlev R H Breyer, Hakan Kaymak, Timon Ax, Florian T A Kretz, Gerd U Auffarth, Philipp R Hagen
Presbyopia and cataract patients' desire for increased spectacle independence after surgery is one of the main drivers for the development of multifocal intraocular lenses (MIOLs) and extended depth of focus (EDOF) intraocular lenses (IOLs). As education, biometry, diagnostics, surgical techniques, and MIOL/EDOF IOL designs have improved over the past decade, an increasing number of cataract surgeons have become cataract-refractive surgeons to help address this need. There is not 1 single MIOL/EDOF IOL, however, that suits all patients' needs...
July 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28780780/intraocular-lens-explantation-after-cataract-surgery-indications-results-and-explantation-techniques
#14
Roberto Fernández-Buenaga, Jorge L Alió
Intraocular lens (IOL) explantation after uneventful cataract surgery is rare but associated with a high risk of complications. In the past few years, the number of published reports about IOL explantation has grown significantly and most of them focus on explantation surgery due to spontaneous late IOL in-the-bag dislocations. This is related to the growth of the pseudophakic population, first as a result of longer lifespans, and second, because the improvements in safety and accuracy of phacoemulsification surgery have led to an increased number of phacorefractive procedures performed in younger patients...
July 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28780778/iol-power-calculation-in-short-and-long-eyes
#15
Kenneth J Hoffer, Giacomo Savini
An analysis of the studies published in the past 50 years reveals that the Haigis, Hoffer Q, and Holladay 2 formulas are the best options for intraocular lens power prediction in short eyes (<22 mm). In long eyes (>26 mm), the Barrett Universal II, Haigis (with optimized constants), Olsen, and SRK/T formulas provide the most accurate outcomes for intraocular lens power prediction.
July 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28780777/femtosecond-laser-assisted-cataract-surgery-technology-outcome-future-directions-and-modern-applications
#16
Joobin Hooshmand, Brendan J Vote
Since its introduction in 2009 femtosecond laser-assisted cataract surgery (FLACS) has promised to revolutionize cataract surgery. Despite its promise, the assessment of FLACS's perceived benefits has proven to be far more complicated than initially might have been thought. Most studies to date have not provided validation of FLACS technology as a clinically significant advancement on our current techniques. We review FLACS technology and outcomes including detailed analysis of safety, efficacy, cost effectiveness and future prospects using data from the literature and our own published clinical experience...
July 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28780776/intraocular-lens-power-calculation-in-eyes-after-laser-in-situ-keratomileusis-or-photorefractive-keratectomy-for-myopia
#17
Adi Abulafia, Warren E Hill, Li Wang, Olga Reitblat, Douglas D Koch
Intraocular power calculation is challenging for patients who have previously undergone corneal refractive surgery. The sources of prediction errors for these eyes are well known; however, the numerous formulas and methods available for calculating intraocular lens power in these cases are eloquent testimony to the absence of a definitive solution. This review discusses some of the available methods for improving the accuracy for predicting the refractive outcome for these patients. It focuses mainly on the methods available on the American Society of Cataract and Refractive Surgery (ASCRS) online calculator and provides some practical guidelines for cataract surgeons who encounter these challenging cases...
July 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28726357/the-complexities-of-negative-dysphotopsia
#18
Ivayla I Geneva, Bonnie A Henderson
The appearance of a dark shadow in the temporal periphery, otherwise known as negative dysphotopsia, continues to be a problem for some patients after routine uncomplicated cataract surgery. Etiologies include type and design of intraocular lens (IOL), anatomical features and dimensions of the eye, pupil size, angle kappa, relationship of the optic to the anterior capsule, and the position of the optic/haptic junction of the IOL. Although the primary etiology remains controversial, it is clear that the cause is multifactorial...
July 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28726356/intrascleral-iol-fixation
#19
Soosan Jacob
Intrascleral sutureless intraocular lens (IOL) fixation utilizes direct haptic fixation within the sclera in eyes with deficient capsular support. This has advantages of long-term stability, good control of tilt and decentration, and lesser pseudophakodonesis. This review summarizes various techniques for intrascleral haptic fixation, results, complications, adaptations in special situations, modifications of the technique, combination surgeries, and intrascleral capsular bag fixation techniques (glued capsular hook)...
July 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28726355/combined-cataract-dsek-dmek-changing-expectations
#20
Francis W Price, Marianne O Price
Endothelial keratoplasty (EK) has revolutionized corneal transplant surgery by providing rapid visual recovery and improved visual outcomes. In parts of the world with Fuchs endothelial dystrophy, many patients may present with both cataracts and corneal degeneration requiring surgery. Other forms of endothelial decompensation may also present with cataracts. The staging or combination of transplant surgery and cataract surgery depend on both the abilities of the surgeon and the surgical techniques being considered...
July 2017: Asia-Pacific Journal of Ophthalmology
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