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Asia-Pacific Journal of Ophthalmology

Xiaoying Wang, Xingtao Zhou
The purpose of this article is to provide updates on the treatment of high myopia with the implantable collamer lens (ICL). The ICL has become an important technique used in intraocular refractive surgery. With improvements in material, design, and application, the ICL has good efficacy, predictability, long-term safety and stability, manageable complications, and reversibility. More and more refractive surgeons are taking note of the ICL. This article reviews the material characteristics and the latest designs of the ICL along with the clinical applications, visual quality, and future development...
November 2016: Asia-Pacific Journal of Ophthalmology
Bhaskar Srinivasan, Hiu Ying Leung, He Cao, Shu Liu, Lizhen Chen, Alex Hoi Fan
Improved efficacy, predictability, and safety of modern phacoemulsification have resulted in cataract surgery being considered as a refractive procedure. Refractive lens exchange by definition is a surgery aimed at replacing the cataractous or clear crystalline lens with an intraocular lens (IOL) in cases of high ametropia. The excellent intraocular optics of this procedure provide a better visual outcome as compared with laser refractive surgery in high myopia. With advances in technology and IOL formulas, the predictability of refractive outcome after cataract surgery in high myopes has improved...
November 2016: Asia-Pacific Journal of Ophthalmology
Germano Leal Ehlke, Ronald R Krueger
Myopia is a generally benign refractive error with an increasing prevalence worldwide. It can be corrected temporarily with glasses and contact lenses and permanently with laser vision correction. The 2 main procedures currently being performed for myopia correction are photorefractive keratectomy and laser-assisted in situ keratomileusis. Each technique has its advantages, but they appear to yield similar visual outcomes 1 year after surgery. Laser vision correction for myopia was considered a paradigm shift because healthy eyes could now undergo a surgical procedure to permanently and safely correct the error by altering the center of the cornea, which was previously off limits because of the potential for loss of transparency...
November 2016: Asia-Pacific Journal of Ophthalmology
Xiao Yang, Zhouyue Li, Junwen Zeng
Myopia has become a worldwide public health issue. Recent studies have consistently reported that orthokeratology (Ortho-K) significantly inhibits the progression of myopia by slowing the elongation of axial length. It has been hypothesized that this effect results from the induction of peripheral myopic defocus, which is a result of the effects of the Ortho-K lenses on the midperipheral corneal topography. Previous studies have investigated the relationship between predicting factors and the inhibitory effect of Ortho-K for slowing childhood myopic progression and found some meaningful results; however, some of the findings are controversial...
November 2016: Asia-Pacific Journal of Ophthalmology
Donald Tan, Su Ann Tay, Kai-Lyn Loh, Audrey Chia
Efforts to reduce myopia progression in childhood are driven by the increasing incidence of high myopia and its attendant health risks. Interventional approaches to reduce myopia progression in childhood have included the use of spectacles, contact lens, and pharmacological methods, of which the latter appear to be most promising. We review the use of topical atropine eye drops in the retardation of myopia progression in children and discuss the efficacy and safety profiles when used at different concentrations (1...
November 2016: Asia-Pacific Journal of Ophthalmology
Kyoko Ohno-Matsui
Pathologic myopia (PM) is the only myopia that causes the loss of best-corrected visual acuity. The main reason for best-corrected visual acuity loss is complications specific to PM, such as myopic maculopathy, myopic traction maculopathy, and myopic optic neuropathy (or glaucoma). The meta-analyses of the PM study group (META-PM study) made a classification system for myopic maculopathy. On the basis of this study, PM has been defined as eyes having atrophic changes equal to or more severe than diffuse atrophy...
November 2016: Asia-Pacific Journal of Ophthalmology
Yanxian Chen, Wei Wang, Xiaotong Han, William Yan, Mingguang He
Myopia has become epidemic, particularly in East Asia, and is a major cause of visual impairment worldwide. Twin studies are an important resource to investigate the genetics and the gene-environment interaction in myopia. This article aims to provide an overview of major findings regarding myopia from different types of twin studies, from the heritability of myopia-related traits to novel findings of genome-wide association studies. In the postgenomic era, twin studies will continue to serve as a unique method in the investigation of gene-environment interaction...
November 2016: Asia-Pacific Journal of Ophthalmology
Kathryn Ailsa Rose, Amanda Nicole French, Ian George Morgan
The prevalence of myopia in developed countries in East and Southeast Asia has increased to more than 80% in children completing schooling, whereas that of high myopia has increased to 10%-20%. This poses significant challenges for correction of refractive errors and the management of pathological high myopia. Prevention is therefore an important priority. Myopia is etiologically heterogeneous, with a low level of myopia of clearly genetic origins that appears without exposure to risk factors. The big increases have occurred in school myopia, driven by increasing educational pressures in combination with limited amounts of time spent outdoors...
November 2016: Asia-Pacific Journal of Ophthalmology
Yee-Ling Wong, Seang-Mei Saw
The myopia epidemic in Asia is evident because the prevalence of high myopia among young adults is higher among Asian (6.8%-21.6%) compared with non-Asian populations (2.0%-2.3%). High myopia is linked to pathologic myopia (PM), which may cause irreversible visual impairment (VI). This review will highlight updates on the prevalence of PM and the associated VI from PM. The prevalence of PM among the middle-aged and elderly (0.9%-3.1%) is higher than the prevalence among children and adolescents (<0.2%). The PM lesions detected among older adults include advanced lesions, such as posterior staphyloma, chorioretinal atrophy, lacquer cracks, and Fuchs spot (in descending frequency of occurrence)...
November 2016: Asia-Pacific Journal of Ophthalmology
Pei-Chang Wu, Hsiu-Mei Huang, Hun-Ju Yu, Po-Chiung Fang, Chueh-Tan Chen
Myopia is not a simple refractive error, but an eyesight-threatening disease. There is a high prevalence of myopia, 80% to 90%, in young adults in East Asia; myopia has become the leading cause of blindness in this area. As the myopic population increases globally, the severity of its impact is predicted. Approximately one fifth of the myopic population has high myopia (≥-6 diopters), which results in irreversible vision loss such as retinal detachment, choroidal neovascularization, cataracts, glaucoma, and macular atrophy...
November 2016: Asia-Pacific Journal of Ophthalmology
Ian G Morgan, Mingguang He, Seang Mei Saw, Ronald R Krueger, Dennis S C Lam
No abstract text is available yet for this article.
November 2016: Asia-Pacific Journal of Ophthalmology
Jasmine H Francis, Ariana M Levin, David H Abramson
PURPOSE: The aim of this study was to review peer-reviewed articles on ophthalmic oncology (specifically retinoblastoma and uveal melanoma) published from January to December 2014. DESIGN: This study is a literature review. METHODS: The terms retinoblastoma and uveal melanoma were used in a MEDLINE literature search. Abstracts were studied, and the most relevant articles were selected for inclusion and further in-depth review. RESULTS: In retinoblastoma, more eyes are being salvaged due to intravitreal melphalan...
September 2016: Asia-Pacific Journal of Ophthalmology
Surabhi Ruia, Sandeep Saxena, Chui Ming Gemmy Cheung, Jagjit S Gilhotra, Timothy Y Y Lai
Spectral domain optical coherence tomography (SD-OCT) is fast becoming the current standard of care for the detection and assessment of diabetic macular edema. With the application of SD-OCT for imaging of retinal microstructure and measurement of retinal thickness, new information regarding disease characteristics has been gathered, which was unrecognized previously. Retinal thickness measurements on SD-OCT have also been used for deciding the management and monitoring of the disease. Since its development, OCT has enhanced the understanding of retinal anatomical changes in diabetic retinopathy...
September 2016: Asia-Pacific Journal of Ophthalmology
Suber S Huang, Chad Marcantonio
No abstract text is available yet for this article.
September 2016: Asia-Pacific Journal of Ophthalmology
Gail Melva Ormsby, Dawn Grant-Skiba, Kovin Naidoo, Jill E Keeffe
PURPOSE: To assess the perspectives of patients who acquired spectacles from an eye unit/vision center in Cambodia. DESIGN: A sample (n = 62) of patients was selected across 4 provinces: Prey Veng, Siem Reap, Battambang, and Takeo. METHODS: The Patient Spectacle Satisfaction Survey covering demographic and semistructured questions regarding patient satisfaction, style, and costs incurred was used to collect data. Information was transcribed and translated into English and analyzed by thematic coding using NVivo...
September 2016: Asia-Pacific Journal of Ophthalmology
Kirthi Kumar Naidu Sugnanam, Shirley Ma, Andreas Kreis, Marcelino Correia, Nitin Verma, Mohamed Dirani
PURPOSE: This study aimed to present the methodology of the East Timor Eye Program and report the prevalence of eye disease seen at the National Eye Centre during a 3-month sample period between June and August 2012. DESIGN: Two hundred ninety-three new patients aged 17 years or older were assessed at the National Eye Centre in Dili, Timor-Leste. METHODS: All participants received a comprehensive dilated eye examination that included distance visual acuity measurements, indirect fundoscopy, and a complete slit lamp assessment including gonioscopy and intraocular pressure measurement...
September 2016: Asia-Pacific Journal of Ophthalmology
Amrita Verma, Manish Nagpal, Navneet Mehrotra
PURPOSE: The aim of this study was to measure the largest hyporeflective (LHR) lumen in the choroid and subfoveal choroidal thickness (SFCT) in patients with diabetic retinopathy (DR) and in control subjects using enhanced depth imaging (EDI) spectral domain optical coherence tomography (SD-OCT). DESIGN: This was a prospective, cross-sectional study. METHODS: This was a study of 240 eyes of DR patients (n = 120) and control subjects (n = 120) matched for age, sex, and refractive error...
September 2016: Asia-Pacific Journal of Ophthalmology
Jaya Gupta, Shiva Prasad Gantyala, Seema Kashyap, Radhika Tandon
PURPOSE: Corneal keloids are rare lesions that develop in cases of corneal insult. We describe the clinical features, subsequent management, and histopathological characteristics of 5 of our cases of corneal keloid. DESIGN: This was an interventional case series. METHODS: A total of 5 patients were examined and treated for corneal keloid. RESULTS: Five Indian patients with no keloids on the skin or any history of hypertrophic scar formation complained of progressive painless dimness of vision and a slowly growing epicorneal mass...
September 2016: Asia-Pacific Journal of Ophthalmology
Rahul Bhargava, Prachi Kumar, Shiv Kumar Sharma, Yogesh Arora
PURPOSE: To compare the safety and efficacy of phacoemulsification and manual small incision cataract surgery (SICS) to treat cataract in patients with Fuchs heterochromic iridocyclitis (FHI). DESIGN: A randomized, double-masked, prospective, multicenter study. METHODS: Consecutive patients with cataract after FHI were randomly assigned to have phacoemulsification or manual SICS by 1 of 2 surgeons experienced in both techniques. Complications (intraoperatively and postoperatively), operative time, visual acuities, endothelial cell counts, and surgically induced astigmatism were compared...
September 2016: Asia-Pacific Journal of Ophthalmology
Sailaja Bondalapati, Subhadra Jalali, Jay Chhablani
PURPOSE: This study aimed to report the outcomes of antivascular endothelial growth factor (anti-VEGF) monotherapy for choroidal neovascularization (CNVM) associated with retinochoroidal coloboma (RCC). DESIGN: A retrospective case series. METHODS: This was a case series of 3 eyes with CNVM associated with RCC that presented to the LV Prasad Eye Institute, Hyderabad, India, between January 2006 and January 2014. Reported data included demographics, preoperative details (symptoms, duration of symptoms, and visual acuity), treatment methods, and postoperative details (visual acuity, follow-up, and recurrence)...
September 2016: Asia-Pacific Journal of Ophthalmology
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