Read by QxMD icon Read

Balkan Medical Journal

Yiğit Düzköylü, Orhan Aras, Erdal Birol Bostancı, Tülay Keklik Temuçin, Murat Ulaş
AIMS: Mixed adeno-neuroendocrine carcinoma is a rare entity, diagnosed with immunohistochemical studies. Literature mainly includes case reports and series which are very few. In our study, we aimed to report a case series from a tertiary hospital with demographics of the patients, detailed tumor and clinical findings and follow-up plus survival conditions. METHODS: Pathology database was explored for patients with the pathological diagnosis of 'mixed adeno-neuroendocrine carcinoma' and patients were identified retrospectively and evaluated in means of demographics, histopathological examination, tumor properties...
March 19, 2018: Balkan Medical Journal
Gözde Yeşil, Ayşe Aralaşmak, Enes Akyüz, Dilara İçağasıoğlu, Türkan Uygur Şahin, Yavuz Bayram
BACKGROUND: The KCNMA1 gene encodes the α-subunit of the large conductance, voltage and calcium-sensitive potassium channel (BK channels) which plays an important role in neuronal excitability. Heterozygous mutations in KCNMA1 were firstly described in a large family with generalized epilepsy and paroxysmal nonkinesigenic dyskinesia. Recently, homozygous KCNMA1 mutations were reported to cause a phenotype of cerebellar atrophy, developmental delay and seizures. CASE REPORT: Herein; we report a patient with a novel homozygous truncating mutation in KCNMA1 (p...
March 16, 2018: Balkan Medical Journal
Ifeyinwa E Obiorah, Alicia Henao Velasquez, Bhaskar Kallakury, Metin Özdemirli
BACKGROUND: Langerhans cell histiocytosis is characterized by abnormal proliferation of neoplastic Langerhans cells. Langerhans cell histiocytosis commonly affects the pediatric population and presentation in adults remain a rare event. The presentation of langerhans cell histiocytosis is highly variable but skin, bone and lung involvement are very common. Langerhans cell histiocytosis presenting as a bile duct mass is rare and usually occurs as part of a multi-organ system disease. CASE REPORT: We present a case of langerhans cell histiocytosis confined to the extrahepatic bile duct in a 62-year-old female with sclerosing cholangitis...
March 8, 2018: Balkan Medical Journal
Michael Samarinas, Kyriakos Moysidis, Pigi Perdikaki, Stavros Gravas
No abstract text is available yet for this article.
February 27, 2018: Balkan Medical Journal
Tuğba Alarcon Martinez, Naciye Dilara Zeybek, Sevda Müftüoğlu
BACKGROUND: Recently, cytotoxic effects of statins on breast cancer cells have been reported. However, the mechanism of anti-proliferative effects is currently unknown. Autophagy is a non-apoptotic programmed cell death, which is characterized by degradation of cytoplasmic components and with a role in cancer pathogenesis. AIMS: To investigate the anti-proliferative effects of atorvastatin was on MCF-7 human breast adenocarcinoma cells in aspect of autophagy and apoptosis...
February 27, 2018: Balkan Medical Journal
Berk Arapi, Burcu Bayoğlu, Müjgan Cengiz, Ahmet Dirican, Serkan Burç Deser, Yerik Junusbekov, Caner Arslan
BACKGROUND: Carotid artery stenosis (CAS) is the atherosclerotic narrowing of the proximal internal carotid artery (ICA) and one of the main causes of stroke. Elevated expression of the pleiotropic proinflammatory cytokine, interleukin-18 (IL18), has been shown in human atherosclerotic plaques. AIMS: To investigate whether IL18 and interleukin-18 binding protein (IL18BP) mRNA expression and IL18 -137 G/C (rs187238) variants are associated with CAS development. STUDY DESIGN: Case-control study...
February 27, 2018: Balkan Medical Journal
Can Konca, Ali Abbas Yılmaz, Süleyman Utku Çelik, Selami Ilgaz Kayılıoğlu, Özge Tuğçe Paşaoğlu, Halil Arda Ceylan, Volkan Genç
BACKGROUND: Staple-line leak is the most frightening complication of laparoscopic sleeve gastrectomy and several predisposing factors such as using improper staple sizes regardless of gastric wall thickness, narrower bougie diameter and ischemia of the staple line are asserted. AIMS: The goal of this study was to evaluate the effects of different bougie diameters on tissue oxygen partial pressure at the esophagogastric junction after sleeve gastrectomy. STUDY DESIGN: The study was designed as a randomized and controlled animal experiment with 1:1:1:1 allocation ratio...
February 20, 2018: Balkan Medical Journal
Oana Bulat, Cristian Bulat, Mihaela Blaj, Ioana Lupusoru, Viorel Scripcariu
BACKGROUND: Schewanella spp. is Gram-negative bacteria, saprophytes and rarely pathogenic. Initially isolated in 193, these belong to the marine environment; Schewanella (Pseudomonas) putrefaciens was found in water, soil and animal sources and produces hydrogen sulphide. Saccharomyces cerevisiae is the well-known yeast used for fermentation in industry and in molecular biology for research. In humans, it is a very rare pathogen which colonises the digestive tract and its utility has been linked to the treatment and prevention of diarrhoea associated with Clostridium difficile...
February 15, 2018: Balkan Medical Journal
Mustafa Serinken, Cenker Eken, Özgür Karcıoğlu
BACKGROUND: Dysmenorrhea is one of the most common acute pain disorders among women of reproductive age. AIMS: The present study aimed to compare the effects of IV paracetamol to dexketoprofen in patients presented with primary dysmenorrhea to the emergency department. STUDY DESIGN: Randomized Controlled Trial. METHODS: Patients over 18 years old presented with pelvic pain related to menstruation were accepted as eligible for the study...
February 2, 2018: Balkan Medical Journal
Li Xia, Liu Li-Feng, Liu Yang-Zhou, Pan Yu-Tao, Li Guang, Lu Qing-You, Yuan Wen, Li Zeng-Chun
BACKGROUND: Even though epidermal growth factor-like domain 7 is known to be overexpressed in osteosarcoma and is associated with poor clinical outcome, few reports are available regarding its mechanism. AIMS: The objective of this study was to explore the effect and mechanism of downregulating epidermal growth factor-like domain 7 expression in a human osteosarcoma cell line on the biological function of cocultured human umbilical vein endothelial cells. STUDY DESIGN: Cell study...
January 24, 2018: Balkan Medical Journal
Cem Uzun
No abstract text is available yet for this article.
March 15, 2018: Balkan Medical Journal
Camelia Sultana, Ana Maria Schweitzer, Mihaela Bogdan, Simona Ruta
No abstract text is available yet for this article.
March 15, 2018: Balkan Medical Journal
Mustafa Erdoğan Cicik, Cezmi Doğan, Selim Bölükbaşı, Mehmet Necdet Cinhüseyinoğlu, Osman Şevki Arslan
BACKGROUND: Pediatric cataract surgery differs substantially from adult cataract surgery. Numerous studies have focused on reducing the development of postoperative complications. AIMS: To compare two intraocular lens implantation techniques used in pediatric cataract surgery in terms of postoperative complications. STUDY DESIGN: Case-control study. METHODS: Patients who underwent pediatric cataract surgery and intraocular lens implantation between 2008 and 2016 were evaluated in this retrospective study...
March 15, 2018: Balkan Medical Journal
Mustafa Erdoğan Cicik, Cezmi Doğan, Osman Şevki Arslan
BACKGROUND: Development of endophthalmitis during cataract surgery is one of the most severe complications and it may also result in blindness and globe loss. AIMS: To evaluate the effect of an ophthalmic cefuroxime solution (Aprokam® ) that is prophylactically used in phacoemulsification surgery performed due to cataract that eventually occurs in patients with or without penetrating keratoplasty. STUDY DESIGN: Case-control study. METHODS: In this retrospective study, patients who had undergone penetrating keratoplasty and for whom phacoemulsification surgery was performed due to cataract and an intracameral ophthalmic cefuroxime solution (Aprokam® ) was administered for prophylaxis were evaluated in comparison with patients with cataract without keratoplasty...
March 15, 2018: Balkan Medical Journal
Nahide Ekici Günay, Sabahattin Muhtaroğlu, Abdulkadir Bedirli
BACKGROUND: Free radical damage is known to occur during liver regeneration. The Ginkgo biloba extract EGb761 has antioxidant properties due to its ability to scavenge free radicals. FK506 has been widely used as an immunosuppressant that stimulates hepatocyte proliferation following partial hepatectomy. AIMS: To explore whether EGb761 enhances liver regeneration after hepatectomy in rats, we investigated the effects of EGb761 alone and in combination with FK506 on the liver regenerative process...
March 15, 2018: Balkan Medical Journal
Akile Sarıoğlu Büke, Özlem Sürel Karabilgin Öztürkçü, Yusuf Yılmaz, İskender Sayek
BACKGROUND: Professionalism education is one of the major elements of surgical residency education. AIMS: To evaluate the studies on core professionalism education programs in surgical professionalism education. STUDY DESIGN: Systematic review. METHODS: This systematic literature review was performed to analyze core professionalism programs for surgical residency education published in English with at least three of the following features: program developmental model/instructional design method, aims and competencies, methods of teaching, methods of assessment, and program evaluation model or method...
March 15, 2018: Balkan Medical Journal
Güldane Cengiz Seval, Pervin Topçuoğlu, Taner Demirer
Hematopoietic stem cell transplantation is an established treatment for patients with a wide range of malignant and nonmalignant conditions. Noninfectious pulmonary complications still remain a leading cause of morbidity and mortality in these patients. Treating hematopoietic stem cell transplantation recipients with noninfectious pulmonary complications is still challenging, and the current treatment armamentarium and strategies are not adequate for patients receiving hematopoietic stem cell transplantation...
March 15, 2018: Balkan Medical Journal
Şifa Turan, Özhan M Turan
The ductus venosus is a fetal vessel that functions importantly in the transfer of oxygen-and nutrient-rich blood from the umbilical vein to vital organs. Its control under active regulation and its anatomy result in a flow-velocity profile that is typically forward throughout the cardiac cycle. This forward cardiac function reflects afterload, cardiac contractility, compliance, and vascular volume changes. Ductus venosus assessment gives valuable information under different fetal conditions. For example, during first trimester screening, an abnormal ductus venosus measurement changes the screening result...
March 15, 2018: Balkan Medical Journal
Emil Mammadov
No abstract text is available yet for this article.
January 20, 2018: Balkan Medical Journal
Süha Ertuğrul, Serdar Ensari
No abstract text is available yet for this article.
January 20, 2018: Balkan Medical Journal
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"