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Journals Problemy Radiat︠s︡i�...

Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï

https://read.qxmd.com/read/38155147/applications-of-three-dimensional-facial-computed-tomography-in-head-and-neck-region-a-review
#1
REVIEW
K Shunmugavelu, H Kannapan, P Vaishnavi, E C Dhinakaran, S Lavanya, B Kumar
3D facial CT has evolved and revolutionized diagnosis leading to better management. The limitations of conventional 2D methods limit the therapeutic options related to leading to an erroneous treatment. Although 3D facial CT is expensive, its advantages outweigh the cons. They are used in surgery, prosthetic replacement, orthodontics and forensics.
December 2023: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://read.qxmd.com/read/38155146/acute-radiation-sickness-in-human-etiopathogenesis-clinic-diagnosis-and-treatment-lecture
#2
JOURNAL ARTICLE
D Belyi, V O Sushko, D A Bazyka
Under the conditions of war in Ukraine, there remains a high probability that russia will use nuclear weapons or commit terrorist acts against nuclear power plants, which will lead to exposure of the population in doses that cause acute radiation sickness (ARS). In this regard, our medical service must be ready for the treatment of ARS of various degrees of severity under a mass influx of victims. In peacetime, ARS is a rather infrequent pathology, so most doctors lack experience in its treatment. This article, having the form of a lecture, presents material on the pathogenesis, classification, clinic, diagnosis and treatment of ARS, taking into account the modern achievements of radiation medicine...
December 2023: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://read.qxmd.com/read/38155145/long-term-outcomes-of-sentinel-lymph-node-biopsy-versus-lymph-node-observation-in-melanoma-patients
#3
RANDOMIZED CONTROLLED TRIAL
M Kukushkina, S Korovin, O Solodiannikova, G Sukach, V Ostafiichuk, S Dedkov
OBJECTIVE: evaluating the influence of sentinel lymph node biopsy without following completion lymph node dissection independent on sentinel lymph node status on the outcome in patients with skin melanoma. MATERIALS AND METHODS: Three hundred nine patients with a primary skin melanoma were randomly assigned to wide excision of the primary tumor and sentinel lymph node biopsy without following completion lymph-node dissection independent on sentinel lymph node status or to wide excision of skin melanoma...
December 2023: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://read.qxmd.com/read/38155144/the-role-of-radiation-therapy-in-the-treatment-of-ptcl-nos
#4
JOURNAL ARTICLE
I Kriachok, O Aleksyk, I Tytorenko, M Bushuieva, Y Moroz
UNLABELLED: Peripheral T-cell lymphomas (PTCLs) are a heterogeneous group of lymphoproliferative disorders, accounting for about 10 % of all non-Hodgkin lymphomas. The most common subtype is peripheral T-cell lymphoma, unclassified (PTCL-NOS), accounting for about 26 % of all PTCLs. PTCL-NOS is associated with less favorable overall survival (OS) and progression-free survival (PFS) compared with aggressive B-cell lymphomas. The role of radiation therapy in the treatment of PTCL-NOS is still not definitively defined...
December 2023: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://read.qxmd.com/read/38155143/role-of-contemporary-imaging-methods-in-radiotherapy-planning-and-monitoring-of-gynecological-cancer-patients-review
#5
REVIEW
V S Ivankova, E A Domina, T V Khrulenko, L M Baranovska, O A Glavin
Radiotherapy (RT) and radiation oncology are of essential role in the clinical treatment of cancer patients. The widely available imaging modalities such as diagnostic ultrasound, computer-assisted tomography, and contrast-enhanced MRI are used in clinical practice for diagnostics and management planning. Moreover, these methods are also used to monitor the treatment upon RT. However, some diagnostic issues cannot be sufficiently resolved by the simple use of standard morphological imaging. Thus, positron emission tomography is gaining an increasing clinical relevance in the management of cancer patients undergoing RT, as it allows to visualize and quantify the tumor features at a molecular level, such as tumor metabolism or receptor expression, beyond simple morphological patterns shown by the conventional imaging...
December 2023: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://read.qxmd.com/read/38155142/prevention-of-reproductive-losses-associated-with-intraplantar-accumulation-of-radionuclides
#6
JOURNAL ARTICLE
A A Zhyvetska/Denysova, I I Vorobiova, N V Rudakova, L A Lozova, O V Shamayeva, S K Stryzhak
UNLABELLED: The materials of the article are based on the results of our past studies of morphological and immunohistochemical features of placental damage due to 137Cs incorporation. OBJECTIVE: to determine the effectiveness of radioprotective therapy in preventing reproductive losses and perinatal consequences associated with the incorporation of radionuclides in the placenta. MATERIALS AND METHODS: According to the research design, the first group consisted of 153 women with reproductive losses in anamnesis and signs of termination of the current pregnancy...
December 2023: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://read.qxmd.com/read/38155141/risk-score-model-for-predicting-cardiotoxicity-in-breast-cancer-diagnostic-value-of-high-sensitivity-cardiac-troponin-t
#7
JOURNAL ARTICLE
N V Dovganych, S M Kozhukhov, I I Smolanka, O F Lygyrda, O Ye Bazyka, S A Lyalkin, O A Yarynkina
UNLABELLED: Cardiovascular diseases are the second leading cause of death among breast cancer (BC) patients. Prediction of cardiovascular toxicity (CT) is an important part of the successful treatment and survival of patients. OBJECTIVE: to develop a risk score model for cardiovascular toxicity (CT) predicting, based on cardiovascular risk factors (RFs), RFs associated with cancer therapy, and troponin levels. MATERIAL AND METHODS: The study included 76 BC patients with a prospective analysis of their clinical and treatment data, RFs, echocardiographic indicators before the start of treatment and after 6 months, and an increase in troponin level...
December 2023: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://read.qxmd.com/read/38155140/the-combination-of-chronic-respiratory-diseases-with-obstructive-sleep-apnoea-syndrome-in-clean-up-workers-of-chornobyl-npp-accident
#8
JOURNAL ARTICLE
L I Shvaiko, K D Bazyka, M V Shilenko, P V Olifer, N A Tkachuk
UNLABELLED: The objective of the study was to establish the relationship between functional status of bronchopulmonary system and obstructive sleep apnea in clean-up workers of Chornobyl NPP accident in a remote post-accident period. MATERIALS AND METHODS: We included 58 COPD male patients clean-up workers of Chornobyl NPP accident: 21 with obstructive sleep apnea syndrome (OSA), 37 - without. A complex of functional tests and OSA screening was provided. RESULTS: In clean-up workers of Chornobyl NPP accident with COPD and obstructive sleep apnea in a remote post-accident period apnea-hypopnea index (AHI) negatively correlated with FVC, % of predicted (r = -0...
December 2023: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://read.qxmd.com/read/38155139/brain-and-eye-as-potential-targets-for-ionizing-radiation-impact-part-v-organic-and-functional-changes-correlation-on-the-example-of-certain-diseases
#9
REVIEW
P Fedirko, T Babenko, K Kuts, M Pilmane, A Yunga, N Garkava
The question about correlation between organic and functional changes in persons, exposed to radiation is still insufficiently studied. Dynamics of morbidity for different forms and classes of non-tumour diseases periodisation, proposed by epidemiologists, suggests the identification of three main periods: «early» (the first 6 post-Chornobyl accident years); «distant» (12-21 years) and «late» (22-30 years). However, the correspondence this periodisation to the results of epidemiological data, without taking into account the clinical features of the diseases, may contribute to the impression, that in the first period after a radiation disaster functional disorders (or autonomic regulation disorders, etc...
December 2023: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://read.qxmd.com/read/38155138/structure-and-characteristics-of-the-chornobyl-npp-accident-victims-according-to-the-materials-of-medical-expertise-of-the-causal-relationship-of-diseases-with-the-effect-of-ionizing-radiation-in-the-remote-postaccidental-period-2023-year
#10
JOURNAL ARTICLE
V O Sushko, O O Kolosynska
UNLABELLED: Loss of health and workability, as well as deaths due to harmful influence of the Chornobyl catastrophe (including radiation exposure) during performance of professional, military or official duties and / or living on radiation-contaminated areas, additional exposure not through their own fault but due to a radiation accident, caused the development of a special form of medical expertise as part of the of medical social protection system for these suffered contingents. OBJECTIVE: To study and characterize the structure of the affected categories (clean-up workers and victims) of the Chornobyl catastrophe based on the materials of expert cases of the Central Interdepartmental Expert Commission of Ministry of Health of Ukraine (CIEC) in the remote post-accidental period (2013-2023)...
December 2023: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://read.qxmd.com/read/38155137/comorbid-pathology-in-fatal-cases-due-to-coronavirus-disease-covid-19-in-victims-of-the-chornobyl-npp-accident
#11
JOURNAL ARTICLE
V O Sushko, D A Bazyka, O O Kolosynska, L M Zvarych
INTRODUCTION: The victims of the Chornobyl accident, as well as whole population of Ukraine, have become the object of the COVID-19 pandemic in today's conditions. As of 01.01.2020, 108,898 victims had documented permanent disability (persons with disabilities) and, as a rule, suffered from 4-6 types of non-tumor chronic diseases of internal organs, primarily the circulatory system, as well as oncological and endocrine pathology, that significantly affect the course of COVID-19 in a severe scenario and contribute to death...
December 2023: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://read.qxmd.com/read/38155136/the-structure-of-the-incidence-of-oncohematological-diseases-in-ecologically-disadvantaged-regions-of-the-dnipropetrovsk-region-for-the-period-2006-2017
#12
JOURNAL ARTICLE
I O Selina, I S Dyagil
OBJECTIVE: to conduct a comparative analysis of the incidence of malignant oncohematological diseases structure among the population of the 4 most ecologically disadvantaged cities of the Dnipropetrovsk region, taking into account the possible influence of various adverse environmental factors (radiation and chemical pollution of air, water and soil) for the period 2006-2017. MATERIALS AND METHODS: 1948 cases of acute myeloblastic and lymphoblastic leukemia, chronic myeloid and lymphocytic leukemia in residents of 4 cities of the Dnipropetrovsk region were analyzed, taking into account the possible influence of adverse environmental factors (radiation, air pollution, etc...
December 2023: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://read.qxmd.com/read/38155135/sleep-quality-of-schoolchildren-residents-of-radioactively-contaminated-areas-during-the-covid-19-pandemic
#13
JOURNAL ARTICLE
V A Poznysh, V Yu Vdovenko, I E Kolpakov, A A Chumak
OBJECTIVE: to assess the sleep characteristics of middle school children during the COVID-19 pandemic. MATERIALS AND METHODS: Cross-sectional study of sleep characteristics of children - residents of radioactively contaminated areas of Zhytomyr and Rivne regions, who underwent a routine examination in June-July 2020, after their stay from March to June 2020 in conditions of home isolation due to quarantine restrictions during the COVID-19 pandemic. Ninety six students of comprehensive public schools, aged 10-16, took part in the study...
December 2023: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://read.qxmd.com/read/38155134/review-of-the-nature-of-anti-inflammatory-and-pro-inflammatory-cytokine-regulation-in-different-periods-of-plasma-cell-myeloma-natural-history-in-the-chornobyl-npp-accident-survivors
#14
JOURNAL ARTICLE
Zh M Minchenko, O O Dmytrenko, Yu O Silaiev, T F Liubarets
OBJECTIVE: identify the nature of anti-inflammatory and pro-inflammatory cytokine regulation in different periods of plasma cell myeloma (PCM) natural history with evaluation of its role as a prognostic criterion for the disease course in the Chornobyl NPP (ChNPP) accident survivors. MATERIALS AND METHODS: Levels of pro-inflammatory (IL-6, TNF-α) and anti-inflammatory (IL-10) cytokines both with their relationship were studied in the stage I-II and stage III PCM patients (n = 74) in different periods of the disease natural history i...
December 2023: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://read.qxmd.com/read/38155133/neurophysiological-basis-of-the-combined-effects-of-acute-stress-and-low-doses-of-ionizing-radiation-on-human-brain
#15
JOURNAL ARTICLE
K V Kuts, T K Loganovska, G Yu Kreinis, I V Perchuk, K Yu Antypchuk, V O Sushko, I M Dykan
OBJECTIVE: to study the clinical and neurophysiological features in the Chornobyl clean-up workers with a verified chronic cerebrovascular disease/cerebral small vessels disease (SVD) exposed to low doses of ionizing radiation (IR), employees of the Chornobyl Nuclear Power Plant (SSE ChNPP), who were exposed to the stress factor of a full-scale war as a result of being held captive by the Russian military at their workplaces, and individuals of the non-irradiated comparison group.Design, object and methods...
December 2023: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://read.qxmd.com/read/38155132/the-role-of-hereditary-predisposition-polymorphic-markers-of-glutathione-s-transferase-catalase-endothelial-nitrogen-oxide-synthase-genes-and-some-adverse-environmental-factors-in-the-development-of-broncho-obstructive-pathology-in-children-living-in-radioactively
#16
JOURNAL ARTICLE
I Ye Kolpakov, V Yu Vdovenko, V M Zyhalo, V G Kondrashova, H M Chobotko, L A Raichuk, O S Leonovych
OBJECTIVE: summarizing the results of many years of research by the authors on the influence of gene polymorphisms encoding xenobiotic biotransformation enzymes (GSTТ1, GSTM1, GSTР1), antioxidant protection (С^262Т of the catalase gene), endothelial nitric oxide synthase (4a/4b VNTR polymorphism of the eNOS gene), and some environmental factors on the occurrence of broncho-obstructive disorders and the development of bronchial asthma in children, residents of radioactively contaminated areas...
December 2023: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://read.qxmd.com/read/38155131/characteristics-of-non-renal-normocalciemic-hyperparathyroidism-in-the-chornobyl-npp-accident-survivors
#17
JOURNAL ARTICLE
O V Kaminskyi, O V Kopylova, D E Afanasyev, I G Chikalova, I M Muraviova, O O Dombrovska, O P Lischenko, L O Tsvet
OBJECTIVE: to assess the hormonal and metabolic disorders in the Chernobyl nuclear power plant (ChNPP) accident survivors (AS), having got secondary normocalcemic non-renal hyperparathyroidism (HPT) in the late period upon exposure to ionizing radiation (IR). MATERIALS AND METHODS: The routine clinical, anthropometric, instrumental (thyroid and parathyroid diagnosticultrasound), laboratory (biochemical, hormonal), statistical methods were applied. In both prospective (n = 48, control group n = 19) and retrospective studies the data of 2,234 subjects including 1,372 irradiated adults (862 non-irradiated persons in the control group) were evaluated...
December 2023: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://read.qxmd.com/read/38155130/the-influence-of-the-war-factor-on-age-changes-in-the-subpopulation-structure-of-leucocytes-as-a-component-of-inflammaging-in-the-groups-of-military-personnel-and-clean-up-workers-of-the-chornobyl-accident
#18
JOURNAL ARTICLE
L M Zvarych, V V Panchenko, N A Golyarnik, O A Belayev, D A Bazyka
OBJECTIVE: to evaluate the subpopulation structure of peripheral blood leukocytes as a component of inflammaging in the servicemen of the Armed Forces of Ukraine and clean-up workers of the accident at the Chornobyl nuclear power plant. MATERIALS AND METHODS: Three hundred ninety-seven males aged 30-82 (54.99 ± 8.85) years examined. Among them: clean-up workers of the accident at the Chornobyl nuclear power plant, aged 54-64 (59.95 ± 1.88) years, who were examined before the beginning and during the Russian military invasion of Ukraine; 24 civilians of the control group, aged 50-77 (58...
December 2023: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://read.qxmd.com/read/38155129/prevalence-of-age-macular-degeneration-in-persons-of-working-age-who-applied-to-participate-in-work-in-action-conditions-ionizing-radiation-preliminary-results
#19
JOURNAL ARTICLE
Yu Yefimova, P Fedirko, T Babenko, R Dorichevska
UNLABELLED: In recent decades, several large-scale epidemiological surveys of the eyes have been conducted to determine the global prevalence of retinal degenerative diseases (for example, the Blue Mountains Eye Study). The results of such studies were evaluated several decades, and the studies themselves required significant material resources. Such large-scale projects have not been carried out in Ukraine.Objective of the work is to study the prevalence of age-related macular degeneration in a pilot group of non-irradiated persons of working age to determine the suitability of using the results for further epidemiological studies in Ukraine...
December 2023: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://read.qxmd.com/read/38155128/the-course-of-chronic-lymphocytic-leukemia-after-sars-cov-2-virus-infection
#20
JOURNAL ARTICLE
I S Dyagil, I V Abramenko, Z V Martina, N A Golyarnic, V V Brychenko, A V Movchan, A A Chumak, D A Bazyka
Objective - to investigate the course of B-cell chronic lymphocytic leukemia (CLL) in patients after SARS-CoV-2 virus infection taking into account anamnestic exposure to the ionizing radiation (IR).Methods. The study was performed in a group of 51 CLL patients who were admitted to the Department of Radiation hematology of the National Research Center for Radiation Medicine of NAMS of Ukraine, Kyiv, from January 2020 (the beginning of SARS-CoV-2 epidemic) to August 2023. The group included 19 (37.3 %) clean-up workers of the Chornobyl NPP accident, 15 (29...
December 2023: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
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