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International Journal of Organ Transplantation Medicine

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https://www.readbyqxmd.com/read/29531648/living-donor-re-transplantation-for-repeated-acute-liver-failure
#1
V Ince, C Kayaalp, E Otan, F Ozdemir, A Dirican, H I Toprak, C Aydin, C Ara, S Yilmaz
Emergency liver transplantation (LT) for acute liver failure (ALF) is a life-saving treatment. Occurrence of this situation in the same patient twice is very rare. Herein, we describe a patient who underwent two emergency LTs for ALF, both from living donors. When she was 26 years old, she underwent a right lobe living donor LT (LDLT) from her sister for ALF due to use of herbal weight loss medications. The next 3 years were uneventful but another ALF developed during a terminal stage pregnancy (37th week)...
2018: International Journal of Organ Transplantation Medicine
https://www.readbyqxmd.com/read/29531647/delayed-hemorrhage-in-kidney-transplantation-a-life-threatening-condition
#2
S Gooran, A Javid, G Pourmand
One of the most catastrophic complications of kidney transplantation is non-traumatic delayed bleeding caused by arterial dissection and pseudoaneurysm, endangering the survival of the graft and the patient. Herein, we discuss the management of this condition in 3 cases. The patients included 2 men, 30 and 47 years old, and a 33-year-old woman, who developed a massive hemorrhage in the second week after kidney transplant. All our patients were diabetic for more than 5 years. Massive hemorrhage occurred in the second week without any trauma or precipitating factor...
2018: International Journal of Organ Transplantation Medicine
https://www.readbyqxmd.com/read/29531646/acute-hepatic-allograft-rejection-in-pediatric-recipients-effective-factors
#3
S M Dehghani, I Shahramian, M Afshari, M Bahmanyar, M Ataollahi, A Sargazi
Background: Acute cellular rejection (ACR), a reversible process, can affect the graft survival. Objective: To evaluate the relation between ACR and clinical factors in recipients of allograft liver transplantation. Methods: 47 recipients of liver were consecutively enrolled in a retrospective study. Their information were retrieved from their medical records and analyzed. Results: Of the 47 recipients, 38 (81%) experienced acute rejection during 24 months of the transplantation...
2018: International Journal of Organ Transplantation Medicine
https://www.readbyqxmd.com/read/29531645/mrna-expression-of-interferon-regulatory-factors-during-acute-rejection-of-liver-transplants-in-patients-with-autoimmune-hepatitis
#4
M Nasiri, B Geramizadeh, S H Nabavizadeh, S A Male-Hosseini, M H Karimi, I Saadat
Background: Interferon regulatory factors (IRFs) can play a critical role in the regulation of many facets of innate and adaptive immune responses through transcriptional activation of type I interferons, other proinflammatory cytokines, and chemokines. However, their roles in transplantation immunity still remain to be elucidated. Objective: To evaluate the time course of mRNA expression of all 9 members of IRFs family of transcription factors during liver allograft acute rejection...
2018: International Journal of Organ Transplantation Medicine
https://www.readbyqxmd.com/read/29531644/prevalence-of-cyp2c19-genetic-polymorphism-among-normal-people-and-patients-with-hepatic-diseases
#5
Z Hashemizadeh, S A Malek-Hosseini, P Badiee
Background: Patients with hepatic diseases are treated with numerous drugs metabolized by cytochrome P450. Objective: To evaluate the frequencies of CYP2C19 variant alleles (*2, *3, and *17), genotypes, and phenotypes, and the relationship between the frequency of these alleles and the underlying hepatic diseases among patients with advanced liver diseases who were candidates for liver transplantation. Methods: The Study was conducted on 120 patients suffering from various hepatic disorders, candidates for liver transplantation, and 52 healthy volunteers...
2018: International Journal of Organ Transplantation Medicine
https://www.readbyqxmd.com/read/29531643/concurrent-umbilical-hernia-repair-at-the-time-of-liver-transplantation-a-six-year-experience-from-a-single-institution
#6
A J Perez, I N Haskins, A S Prabhu, D M Krpata, C Tu, S Rosenblatt, K Hashimoto, T Diago, B Eghtesad, M L J Rosen
Background: Umbilical hernias are common in patients with end-stage liver disease undergoing liver transplantation. Management of those persisting at the time of liver transplantation is important to define. Objective: To evaluate the long-term results of patients undergoing simultaneous primary umbilical hernia repair (UHR) at the time of liver transplantation at a single institution. Methods: Retrospective chart review was performed on patients undergoing simultaneous UHR and liver transplantation from 2010 through 2016...
2018: International Journal of Organ Transplantation Medicine
https://www.readbyqxmd.com/read/29531642/one-year-allograft-and-patient-survival-in-renal-transplant-recipients-receiving-antiplatelet-therapy-at-the-time-of-transplantation
#7
T Benkö, M Gottmann, S Radunz, A Bienholz, F H Saner, J W Treckmann, A Paul, D P Hoyer
Background: Antiplatelet therapy is common in patients on the waiting list for kidney transplantation. Objective: To evaluate the incidence of post-operative bleeding in patients with antiplatelet therapy undergoing kidney transplantation and analyze the impact on the outcome. Methods: We studied all patients with concomitant antiplatelet therapy undergoing kidney transplantation in our center from January 2007 to June 2012. Data were collected by chart review...
2018: International Journal of Organ Transplantation Medicine
https://www.readbyqxmd.com/read/29531641/results-of-kidney-transplantation-from-expanded-criteria-donors-a-single-center-experience
#8
B Palkoci, M Vojtko, J Fialová, D Osinová, M Lajčiaková
Background: Collection of kidneys from extended criteria donors (ECD) with diagnosed brain-death forms a part of the collection program that increases the number of transplantations. Objective: To compare the results of ECD with those of standard criteria donors (SCD). Methods: In a retrospective analysis in a group of 156 kidney donors, we identified ECD donors. We detected the basic parameters of the donors before kidney collection, and then evaluated the function of the graft, the survival of the graft, and the survival of the patients after 1, 3, and 5 years of transplantation...
2018: International Journal of Organ Transplantation Medicine
https://www.readbyqxmd.com/read/29321840/should-we-use-an-orphan-graft
#9
A Baskıran, F Ozdemir, B Barut, V Ince, C Koc, V Ersan, S Karakas, K Kutluturk, S Yılmaz
No abstract text is available yet for this article.
2017: International Journal of Organ Transplantation Medicine
https://www.readbyqxmd.com/read/29321839/liver-transplantation-in-a-myopathic-patient-with-glycogen-storage-disease-type-iiia-and-decompensated-cirrhosis
#10
M Zobeiri
Glycogen storage disease (GSD) type IIIa (Forbes-Cori disease) can be associated with severe liver disease. A patient with GSD type IIIa may therefore be a potential candidate for liver transplantation. Progressive myopathy makes uncertain the outcome of the patient and the transplant. Herein, we report on the good results of liver transplantation up to 28 months after the transplantation in a 40-year-old man with liver cirrhosis and significant muscle weakness due to GSD type IIIa.
2017: International Journal of Organ Transplantation Medicine
https://www.readbyqxmd.com/read/29321838/lung-abscess-an-early-complication-of-lung-transplantation-in-a-patient-with-cystic-fibrosis
#11
I Markelić, M Jakopović, W Klepetko, F Džubur, A Hećimović, M J Makek, M Samaržija, A V Dugac
A 22-year-old woman with cystic fibrosis (CF) developed lung abscess, as a rare complication caused by multidrug-resistant (MDR) Acinetobacter baumannii infection, after lung transplantation (LT). After 6 months of long-term antibiotic therapy, the abscess was successfully eliminated. In reviewed published literature, no previous report was found describing this kind of complication caused by MDR A. baumannii in post-LT patient with CF. In our experience, lung abscess in LT recipients with CF can be successfully treated with prolonged antibiotic therapy...
2017: International Journal of Organ Transplantation Medicine
https://www.readbyqxmd.com/read/29321837/acute-appendicitis-after-liver-transplantation-a-case-report-and-review-of-the-literature
#12
S E Sheppard, H L Marecki, C M Psoinos, B Movahedi, M J Furman, A Bozorgzadeh, P N Martins
Acute appendicitis is one of the most common etiologies for acute abdomen. However, fewer than 30 cases of acute appendicitis after liver transplantation have so far been reported in the literature. Previous case studies have concluded that acute appendicitis after liver transplantation may present differently than in non-immunosuppressed patients and thus may lead to more complications. Herein, we describe the fourth case of laparoscopic appendectomy in a 40-year-old female presenting with an acute abdomen, 10 years after orthotopic liver transplantation for autoimmune hepatitis...
2017: International Journal of Organ Transplantation Medicine
https://www.readbyqxmd.com/read/29321836/acute-hepatic-allograft-rejection-in-pediatric-recipients-independent-factors
#13
S M Dehghani, I Shahramian, M Afshari, M Bahmanyar, M Ataollahi, A Sargazi
Background: Acute cellular rejection (ACR) has a reversible effect on graft and its survival. Objective: To evaluate the relation between ACR and clinical factors in recipients of liver transplant allografts. Methods: 47 consecutive liver recipients were retrospectively studied. Their data were extracted from records and analyzed. Results: 38 (81%) of the 47 recipients experienced ACR during a 24-month follow-up. The rate of rejection was associated with none of the studied factors-recipient's blood group, sex, age, familial history of disease, drugs and blood products received, type of donor, and Child score and class...
2017: International Journal of Organ Transplantation Medicine
https://www.readbyqxmd.com/read/29321835/osteoblast-differentiation-on-collagen-scaffold-with-immobilized-alkaline-phosphatase
#14
F Jafary, P Hanachi, K Gorjipour
Background: In tissue engineering, scaffold characteristics play an important role in the biological interactions between cells and the scaffold. Cell adhesion, proliferation, and activation depend on material properties used for the fabrication of scaffolds. Objective: In the present investigation, we used collagen with proper characteristics including mechanically stability, biodegradability and low antigenicity. Optimization of the scaffold was done by immobilization of alkaline phosphatase on the collagen surface via cross-linking method, because this enzyme is one of the most important markers of osteoblast, which increases inorganic phosphate concentration and promote mineralization of bone formation...
2017: International Journal of Organ Transplantation Medicine
https://www.readbyqxmd.com/read/29321834/increased-c-myc-and-mi-r-33-expression-in-expanded-hematopoietic-stem-cells-cultured-on-adipose-stem-cells-feeder-layer
#15
T Foroutan
Background: Umbilical cord blood has been used for transplantation in regenerative medicine of hematological disorders. MicroRNAs are important regulators of gene expression that control both physiological and pathological processes such as development and cancer. Some studies have shown that miR-33, p53 and c-myc have critical roles in control of self-renewal cells. Objective: To understand the effect of adipose-derived mesenchymal stem cells (ADSCs), as a feeder layer, on expansion of HSCs, the expression of p53 and miR-33a were evaluated...
2017: International Journal of Organ Transplantation Medicine
https://www.readbyqxmd.com/read/29321833/the-learning-curve-of-pure-retroperitoneoscopic-donor-nephrectomy
#16
B C Pal, P R Modi, S J Rizvi, R Chauhan, S Kumar, R Nagarajan, D Kaushal, V B Kute, H L Trivedi
Background: Retroperitoneoscopic donor nephrectomy (RDN) is a well-established modality for the procurement of kidneys for renal transplantation. However the learning curve of pure RDN is not yet defined. Defining the learning curve will help in proper mentorship of the new donor surgeons besides providing safety to the donors. Objective: To define the learning curve of pure RDN. Methods: We analyzed the prospectively collected data of 102 voluntary kidney donors who underwent RDN by a single surgeon between August 2012 and April 2015 at our center...
2017: International Journal of Organ Transplantation Medicine
https://www.readbyqxmd.com/read/29321832/access-to-liver-transplantation-and-patient-survival-among-asian-populations-pre-share-35-vs-post-share-35
#17
Y Zhang
Background: Studies addressing ethnic disparities and trends in liver transplantation for Asian population are scant. Objective: To examine the impact of Share 35 policy on Asian patients' access to liver transplantation and outcomes since its implementation in June 2013. Methods: A total of 11,910 adult white and Asian patients who were registered for deceased donor liver transplantation between 2012 and 2015, was identified from the United Network for Organ Sharing database...
2017: International Journal of Organ Transplantation Medicine
https://www.readbyqxmd.com/read/28959387/classification-models-to-predict-survival-of-kidney-transplant-recipients-using-two-intelligent-techniques-of-data-mining-and-logistic-regression
#18
M Nematollahi, R Akbari, S Nikeghbalian, C Salehnasab
Kidney transplantation is the treatment of choice for patients with end-stage renal disease (ESRD). Prediction of the transplant survival is of paramount importance. The objective of this study was to develop a model for predicting survival in kidney transplant recipients. In a cross-sectional study, 717 patients with ESRD admitted to Nemazee Hospital during 2008-2012 for renal transplantation were studied and the transplant survival was predicted for 5 years. The multilayer perceptron of artificial neural networks (MLP-ANN), logistic regression (LR), Support Vector Machine (SVM), and evaluation tools were used to verify the determinant models of the predictions and determine the independent predictors...
2017: International Journal of Organ Transplantation Medicine
https://www.readbyqxmd.com/read/28924467/how-to-avoid-injury-to-the-renal-artery-due-to-inclusion-of-superior-mesenteric-artery-patch-during-organ-procurement
#19
B V Dasari, S Asthana, N Ahmad
No abstract text is available yet for this article.
2017: International Journal of Organ Transplantation Medicine
https://www.readbyqxmd.com/read/28924466/primary-cutaneous-cd4-positive-small-medium-sized-pleomorphic-t-cell-lymphoma-following-heart-transplantation
#20
B Shakerian, N Razavi, M H Mandegar
Post-transplantation cutaneous lymphoproliferative diseases (PTCLD) are rare, with 29 cases have so far been reported in the literature-only 4 cases underwent cardiac transplantation. Herein, we report on, to the best of our knowledge, the first case in the English literature of primary cutaneous CD4-positive small/medium-sized pleomorphic T-cell lymphoma in a cardiac transplant recipient.
2017: International Journal of Organ Transplantation Medicine
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