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Annals of Neurosciences

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https://www.readbyqxmd.com/read/28867902/adenoid-cystic-carcinoma-presenting-as-abducens-nerve-palsy-secondary-to-cavernous-sinus-lesion
#1
Christopher Donaldson, Bryden Dawes, Vivek Rathi, Kristian Bulluss
BACKGROUND: We report a 61-year-old who presented with a right-sided abducens nerve palsy secondary to a middle cranial fossa adenoid cystic carcinoma (ACC) extending into the cavernous sinus. PURPOSE: This case represents a unique presentation of intracranial ACC with a large middle cranial fossa mass and only a small extracranial component. METHODS: Review of the literature was undertaken to identify cases of intracranial ACC and their range of presentations...
July 2017: Annals of Neurosciences
https://www.readbyqxmd.com/read/28867901/primary-intracranial-extraskeletal-mesenchymal-chondrosarcoma-clinical-mimicry-as-glomus-jugulare
#2
Rajesh Chhabra, Manjul Tripathi, Devi Prasad Patra, Narendra Kumar, Bishan Radotra, Kanchan Kumar Mukherjee
BACKGROUND: Extraskeletal mesenchymal chondrosarcoma (ESMCS) is an unusual pathologic variant of chondrosarcoma. There are no specific clinicoradiographic parameters to distinguish it from other intracranial pathologies. The diagnosis can be established only on the basis of histopathology, which may pose significant challenges in certain unusual locations. PURPOSE: In this case, we discuss the pitfalls in diagnosis, management, and major characteristics of ESMCS with a review of current literature...
July 2017: Annals of Neurosciences
https://www.readbyqxmd.com/read/28867900/diagnostic-markers-of-autoimmune-neuropathological-diseases
#3
Rahul Tyagi
No abstract text is available yet for this article.
July 2017: Annals of Neurosciences
https://www.readbyqxmd.com/read/28867899/homology-modeling-and-protein-interaction-map-of-chrna7-neurogenesis-protein
#4
Ruchi Yadav, Deepshikha Deepshikha, Prachi Srivastava
CHRNA7 is a neurodevelopmental protein involved in differentiation and neurogenesis, which is also named as nicotinic acetylcholine receptors, cholinergic receptor, nicotinic, alpha 7 (neuronal). The protein encoded by this gene forms a homo-oligomeric channel. It is a major component of brain nicotinic receptors displays that are blocked by and sensitive to alpha-bungarotoxin. Studies reports involvement of CHRNA7 protein in different neurological diseases. Non-availability of 3-dimensional (3D) structure leads the study toward structure 3D prediction along with its interaction analysis...
July 2017: Annals of Neurosciences
https://www.readbyqxmd.com/read/28867898/cortical-oligodendrocytes-in-kaolin-induced-hydrocephalus-in-wistar-rat-impact-of-degree-and-duration-of-ventriculomegaly
#5
Olugbenga Ayodeji Ayannuga, Thajasvarie Naicker
BACKGROUND: Oligodendrocytes are critical to the function of the brain. They generate the myelin sheath which ensures saltatory conduction, which is a more energy saving and efficient means of axonal impulse transmission. Ventriculomegaly results in neuronal degeneration and astrogliosis. PURPOSE: The effect of the degree of ventriculomegaly on oligodendrocyte in kaolin-induced hydrocephalus and the timeline have not been extensively documented, hence this study...
July 2017: Annals of Neurosciences
https://www.readbyqxmd.com/read/28867897/extrapyramidal-symptoms-probably-related-to-risperidone-treatment-a-case-series
#6
Sereen Rose Thomson, Bharti Chogtu, Dipanjan Bhattacharjee, Saurabh Agarwal
BACKGROUND: Atypical antipsychotics, like risperidone purportedly, score over their typical counterparts in terms of their lower propensity toward producing extrapyramidal symptoms (EPS). However, recent studies have furnished evidence to the contrary. Hereby, we present a case series implicating risperidone as the causative agent for EPS. METHODS: As a part of the pharmacovigilance programme of India, the authors have assessed 10 physician-reported cases of EPS among the 1,830 patients who were prescribed risperidone within the time period of January 2012-December 2014 in a tertiary care hospital in South India...
July 2017: Annals of Neurosciences
https://www.readbyqxmd.com/read/28867896/neonatal-lipopolysaccharide-infection-causes-demyelination-and-behavioral-deficits-in-adult-and-senile-rat-brain
#7
Kavita Singh, Nisha Patro, M Pradeepa, Ishan Patro
BACKGROUND: Neonatal bacterial infections have been reported to cause white matter loss, although studies concerning the influence of infection on the expression of myelin and aging are still in their emerging state. PURPOSE: The present study aimed to investigate the effects of perinatal lipopolysaccharide (LPS) exposure on the myelination at different age points using histochemical and immunocytochemical techniques and the relative motor coordination. METHODS: A rat bacterial infection model was established by exposing the neonatal rats with LPS (0...
July 2017: Annals of Neurosciences
https://www.readbyqxmd.com/read/28867895/estrous-cycle-phase-dependent-changes-in-anxiety-and-depression-like-profiles-in-the-late-adolescent-wistar-kyoto-rat
#8
Deepthi D'Souza, Monika Sadananda
BACKGROUND: Depression often manifests during adolescence when the development and networking of social and emotional brain areas is being influenced by hormones. The Wistar Kyoto (WKY) rat has been proposed as an animal model of adolescent depression with various face, construct, and predictive validities for clinical depression having been established. PURPOSE: The influence of the estrous cycle on anxiety- and depression-like behaviors in female adolescents may be tested out further using this model...
July 2017: Annals of Neurosciences
https://www.readbyqxmd.com/read/28867894/policy-research-for-assessment-of-quality-assurance-practices-in-skill-development-of-doctoral-programs-in-medical-institutes
#9
Akshay Anand, Rahul Tyagi, Paramvir Kaur
No abstract text is available yet for this article.
July 2017: Annals of Neurosciences
https://www.readbyqxmd.com/read/28867893/incubating-integrative-medicine-in-india-through-pmo-s-atal-incubator-scheme-of-niti-aayog
#10
EDITORIAL
Akshay Anand, Rahul Tyagi, Paramvir Kaur
BACKGROUND: Incubation centers are considered important tools to advance in a field of activity with multidisciplinary approach. The idea of incubation emerged long time back but it is actively pursued by funding agencies as a medium to propel community development. India's fast developing economy had limited tryst with Integrative Medicine until Indian Prime Minister, Narendra Modi, role modelled for Yoga in Chandigarh on the occasion of International Yoga Day. Integrative Medicine is a growing field and widely accepted as a cost-effective problem solving method that simplifies the management of incurable and complex disorders where modern medicine has little to offer...
July 2017: Annals of Neurosciences
https://www.readbyqxmd.com/read/28827919/cerebellar-molecular-and-cellular-characterization-in-rat-models-of-alzheimer-s-disease-neuroprotective-mechanisms-of-garcinia-biflavonoid-complex
#11
Olayemi Joseph Olajide, Anita Temi Ugbosanmi, Bernard Ufuoma Enaibe, Kehinde Yomi Ogunrinola, Susan Folashade Lewu, Nnaemeka Tobechukwu Asogwa, Tosan Akapa, Aminu Imam, Abdulmumin Ibrahim, Ismail Temitayo Gbadamosi, Emmanuel Olusola Yawson
BACKGROUND: Recent evidences suggest that cerebellar degeneration may be associated with the development of Alzheimer's disease (AD). However, previous reports were mainly observational, lacking substantial characterization of cellular and molecular cerebellar features during AD progression. PURPOSE: This study is aimed at characterizing the cerebellum in rat models of AD and assessing the corresponding neuroprotective mechanisms of Garcinia biflavonoid complex (GBc)...
May 2017: Annals of Neurosciences
https://www.readbyqxmd.com/read/28596673/power-spectral-density-analysis-of-electrocorticogram-recordings-during-cerebral-hypothermia-in-neonatal-seizures
#12
Mark H Myers, Elliott Jolly, Yaqin Li, Amy de Jongh Curry, Helena Parfenova
BACKGROUND: Neonatal seizures (NS) are the most common form of neurological dysfunction observed in newborns. PURPOSE: The purpose of this study in newborn piglets was to determine the effect of cerebral hypothermia (CH) on neural activity during pharmacologically induced NS. We hypothesized that the neuroprotective effects of CH would preserve higher frequencies observed in electrocorticogram (ECoG) recordings. METHODS: Power spectral density was employed to determine the levels of brain activity in ECoGs to quantitatively assess the power of each frequency observed in neurological brain states of delta, theta, alpha, and beta-gamma frequencies...
May 2017: Annals of Neurosciences
https://www.readbyqxmd.com/read/28588368/two-cases-of-esophageal-injury-following-anterior-cervical-discectomy-and-fusion-one-overt-and-one-covert
#13
Prasad Krishnan, Rajaraman Kartikueyan, Sachinkumar Maheshbhai Patel, Partha Pratim Bose, Kanchan Kumar Mukherjee
Esophageal perforation is a dreaded complication of anterior cervical spinal surgery. A 52-year-old diabetic man had undergone a surgery for a C6-C7 disc prolapse and developed spiking fever with chills and rigor on the 7th postoperative day. No cause could be found out but a CT scan of thorax done in the course of investigations revealed pneumomediastimum. The patient succumbed on the 10th day after surgery. Autopsy revealed the cause of death to be mediastinitis following iatrogenic esophageal perforation...
May 2017: Annals of Neurosciences
https://www.readbyqxmd.com/read/28588367/neuroscience-symposium-and-workshop-on-saapcon-2016-nepal
#14
Prakash Limbu, Barun Mahat, Bipin Kumar Shrestha, Bikalp Thapa, Mukesh Kumar Jha, Amrendra Jha, Tara Man Amatya, Ajaya Jung Kunwar, Sunil Dhungel
Physiological Society of Nepal, with support from the South Asian Association of Physiologists (SAAP), organized the 5th Biennial Conference of the South Asian Association of Physiologists in conjunction with the 2nd Annual Conference of Physiological Society of Nepal. The purpose of this conference is to bring the scientists, researchers, and students from the South Asian countries in one platform to share and discuss the recent advances and achievements in the field of physiology. Since physiology is the backbone of medical science which deals with the functions of the human body, the theme of the conference was given as "Redefining health in nature...
May 2017: Annals of Neurosciences
https://www.readbyqxmd.com/read/28588366/neurocognitive-effect-of-nootropic-drug-brahmi-bacopa-monnieri-in-alzheimer-s-disease
#15
REVIEW
Kaustubh S Chaudhari, Nishant R Tiwari, Rakesh R Tiwari, Rohan S Sharma
Alzheimer's disease (AD) is a progressive neurodegenerative disease of the elderly. The rapid increase in its incidence has necessitated development of newer drugs. Ayurvedic herbal medications are increasingly researched due to their biosafety profile and usefulness in cognitive impairment. In this article, we critically reviewed one such Medhya Rasayana (nootropic drug) Brahmi-derived from extract of Bacopa monnieri (EBm). Studies have shown that EBm promotes free radical scavenger mechanisms and protects cells in prefrontal cortex, hippocampus, and striatum against cytotoxicity and DNA damage implicated in AD...
May 2017: Annals of Neurosciences
https://www.readbyqxmd.com/read/28588365/prevalence-and-trends-in-the-neuropsychological-burden-of-patients-having-intracranial-tumors-with-respect-to-neurosurgical-intervention
#16
Manju Dhandapani, Sandhya Gupta, Manju Mohanty, Sunil Kumar Gupta, Sivashanmugam Dhandapani
BACKGROUND: The burden of neuropsychological symptoms evidenced by behavioral changes among patients with intracranial tumors has not been studied in detail. PURPOSE: This study was conducted to prospectively assess the neuropsychological symptoms in patients with intracranial tumors undergoing treatment. METHODS: A longitudinal study was conducted using purposive sampling to assess the neuropsychological symptoms in conscious and consenting patients with intracranial tumors who were availing treatment from a tertiary care center...
May 2017: Annals of Neurosciences
https://www.readbyqxmd.com/read/28588364/extinction-of-contextual-fear-with-timed-exposure-to-enriched-environment-a-differential-effect
#17
Preethi Hegde, Shane O'Mara, Thenkanidiyoor Rao Laxmi
BACKGROUND: Extinction of fear memory depends on the environmental and emotional cues. Furthermore, consolidation of extinction is also dependent on the environmental exposure. But, the relationship of the time of the exposure to a variety of environmental cues is not well known. The important region involved in facilitation of extinction of fear memory is through diversion of the flow of information leaving the lateral nucleus of amygdala. PURPOSE: The study aimed to address a question to explain how these brain regions react to environmental stimulation during the retention and extinction of fear memory...
May 2017: Annals of Neurosciences
https://www.readbyqxmd.com/read/28588363/blood-oxygenation-level-dependent-functional-mri-of-early-evidences-of-brain-plasticity-after-hemodialysis-session-by-helixone-membrane-of-patients-with-indices-of-adrenal-deficiency
#18
Saïd Boujraf, Rachida Belaïch, Abdelkhalek Housni, Mustapha Maaroufi, Siham Tizniti, Tarik Sqalli, Mohammed Benzagmout
BACKGROUND: Various alterations of hypothalamic-pituitary-adrenal axis function have been described in patients with chronic renal failure. Nevertheless, controversial evidences were stated about the association between adrenal function deficiency (AD) and hemodialysis (HD). PURPOSE: The goal of this paper was to estimate indirect indices of the adrenal gland dysfunction which is potentially influenced by oxidative stress (OS) that still generates brain plasticity and reorganization of the functional control...
May 2017: Annals of Neurosciences
https://www.readbyqxmd.com/read/28588362/folic-acid-modulates-matrix-metalloproteinase-2-expression-alleviates-neuropathic-pain-and-improves-functional-recovery-in-spinal-cord-injured-rats
#19
Gurwattan S Miranpuri, Sivan Vadakkadath Meethal, Emmanuel Sampene, Abhishek Chopra, Seah Buttar, Carrie Nacht, Neydis Moreno, Kush Patel, Lisa Liu, Anupama Singh, Chandra K Singh, Nithya Hariharan, Bermans Iskandar, Daniel K Resnick
BACKGROUND: The molecular underpinnings of spinal cord injury (SCI) associated with neuropathic pain (NP) are unknown. Recent studies have demonstrated that matrix metalloproteinases (MMPs) such as MMP2 play a critical role in inducing NP following SCI. Promoter methylation of MMPs is known to suppress their transcription and reduce NP. In this context, it has been shown in rodents that folic acid (FA), an FDA approved dietary supplement and key methyl donor in the central nervous system (CNS), increases axonal regeneration and repair of injured CNS in part via methylation...
May 2017: Annals of Neurosciences
https://www.readbyqxmd.com/read/28588361/caffeine-and-cannabis-effects-on-vital-neurotransmitters-and-enzymes-in-the-brain-tissue-of-juvenile-experimental-rats
#20
J O Owolabi, S Y Olatunji, A J Olanrewaju
BACKGROUND: Caffeine and cannabis are globally consumed and abused psychoactive substances. While caffeine is legally used in various forms, including in tea and coffee as beverages, it is also consumed in soda and energy drinks as additives. Cannabis, on the other hand, is considered illegal in most countries; albeit, it is being consumed globally particularly by adolescents. PURPOSE: The adolescent stage marks a critical stage of brain development and maturation...
May 2017: Annals of Neurosciences
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