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Shanghai Archives of Psychiatry

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https://www.readbyqxmd.com/read/28904516/the-differences-and-similarities-between-two-sample-t-test-and-paired-t-test
#1
Manfei Xu, Drew Fralick, Julia Z Zheng, Bokai Wang, Xin M Tu, Changyong Feng
In clinical research, comparisons of the results from experimental and control groups are often encountered. The two-sample t-test (also called independent samples t-test) and the paired t-test are probably the most widely used tests in statistics for the comparison of mean values between two samples. However, confusion exists with regard to the use of the two test methods, resulting in their inappropriate use. In this paper, we discuss the differences and similarities between these two t-tests. Three examples are used to illustrate the calculation procedures of the two-sample t-test and paired t-test...
June 25, 2017: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/28904515/psychogenic-polydipsia-management-challenges
#2
M S Bhatia, Aparna Goyal, Rashmita Saha, Nimisha Doval
Compulsive water drinking or psychogenic polydipsia is now increasingly seen in psychiatric populations. Effects of increased water intake can lead to hyponatremia causing symptoms of nausea, vomiting, seizures, delirium and can even be life threatening if not recognized and managed early. Here we present a 35-year old adult who was diagnosed with psychogenic polydipsia and was successfully managed with a combination of pharmacotherapy, fluid restriction and psychosocial management.
June 25, 2017: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/28904514/hyponatremia-with-olanzapine-a-suspected-association
#3
Ankur Sachdeva, Mona Choudhary
Hyponatremia is a rare, yet potentially life threatening complication of antipsychotics. Here, we report a case of a 45-year-old female diagnosed with schizophrenia who developed hyponatremia soon after addition of olanzapine to the existing treatment. This prompted us to evaluate the relationship between hyponatremia and olanzapine, as timely management is crucial. Naranjo algorithm established a "probable" causal relation between olanzapine and hyponatremia. Possible etiological reasons of this clinically significant and life threatening adverse event have been discussed...
June 25, 2017: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/28904513/autoimmune-thyroiditis-presenting-as-psychosis
#4
Soumitra DAS, Nimisha Doval, Vikas Moun
Hashimoto's thyroiditis is a rare condition associated mainly with neurological symptoms. It contains an abundant amount of auto-antibodies in the blood. Only a few cases of behavioral symptoms without significant neurological disturbances have been recorded in the literature. In this view, our case is unique as it was not associated with overt hypothyroid manifestations.
June 25, 2017: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/28904512/is-depression-the-result-of-immune-system-abnormalities
#5
Xiaoyun Guo, Kaida Jiang
The etiology of Major Depressive Disorder (MDD) is still unclear. We reviewed the literature for the relationship between inflammatory signaling and cytokines in the pathogenesis of MDD. In addition, we provid evidence for adjunctive treatment using anti-inflammatory drugs to improve the therapeutic effect and prognosis. Finally, we explore the possible relationship between the pathogenesis of MDD and immune disturbances.
June 25, 2017: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/28904511/the-fantasmatic-and-imaginary-child-of-the-pregnant-woman
#6
Simone Setterberg
BACKGROUND: Pregnancy is a period of transition, which makes women more vulnerable and in unfavorable conditions may lead to psychopathology in both mother and infant. It is essential to outline factors adversely affecting the resolution of this period. Early interventions and why they matter: Interventions during pregnancy can provide important improvement in the outcome for both maternal and infant mental health. AIM: The aim of the study is to evaluate the risk factors of antenatal anxiety and depression focusing particularly on maternal representations of the relationship towards the fetus and her own parents during pregnancy and the early postpartum period...
June 25, 2017: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/28904510/dysfunction-of-cognition-patterns-measured-by-matrics-consensus-cognitive-battery-mccb-among-first-episode-schizophrenia-patients-and-their-biological-parents
#7
Aiai Cao, Ting Shen, Haibin Li, Chuangxin Wu, Marita McCabe, David Mellor, Linda Byrne, Jie Zhang, Jia Huang, Daihui Peng, Yifeng Xu
BACKGROUND: Schizophrenia is characterized by abnormal perception, thinking, emotions, and behaviors. Cognitive dysfunction is acknowledged as one of the most pivotal symptoms in schizophrenia. In addition to positive or negative symptoms, which had been proposed by Gallhofer in the early 1970s, schizophrenia patients suffered from cognitive impairments as well. Many studies show that there is genetic susceptibility in the first grading kinship of patients with schizophrenia. Patients with schizophrenia have cognitive impairment not only in the acute phase but also in the stable phase...
June 25, 2017: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/28904509/peripheral-slc6a4-gene-expression-in-obsessive-compulsive-disorder-in-the-han-chinese-population
#8
Xuemei Wang, Qing Zhao, Wen Chen, Shunying Yu, Zhen Wang, Zeping Xiao
BACKGROUND: Serotonergic system dysfunction has been implicated in obsessive-compulsive disorder (OCD). This study examined peripheral SLC6A4 gene expression in OCD patients and healthy controls to explore the relationship between SLC6A4 and OCD. METHODS: Participants included 50 first episode OCD patients and 60 age and gender-matched healthy controls. Relative SLC6A4 gene expression were examined by real-time quantitative reverse transcription polymerase chain reaction (RT-PCR) in peripheral leukocytes of all the subjects...
June 25, 2017: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/28904508/changes-in-cognitive-function-in-patients-with-primary-insomnia
#9
Hui Guo, Meijie Wei, Wantao Ding
BACKGROUND: Neuropsychological evidence is not sufficient concerning whether there is cognitive impairment in patients with primary insomnia. Further study is needed in this regard. AIMS: To measure the changes in cognitive functioning in patients with primary insomnia. METHODS: 40 patients with insomnia (insomnia group) and 48 normal sleepers (control group) were tested using the Pittsburgh Sleep Quality Index (PSQI), episodic memory test, and Montreal Cognitive Assessment (MoCA)...
June 25, 2017: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/28904507/adjunctive-melatonin-for-tardive-dyskinesia-in-patients-with-schizophrenia-a-meta-analysis
#10
Chen-Hui Sun, Wei Zheng, Xin-Hu Yang, Dong-Bin Cai, Chee H Ng, Gabor S Ungvari, Hai-Yan Li, Yu-Jie Wu, Yu-Ping Ning, Yu-Tao Xiang
BACKGROUND: Tardive dyskinesia (TD) is characterized by abnormal and involuntary movements. Importantly, TD could cause considerable personal suffering and social and physical disabilities. AIMS: This meta-analysis based on randomized controlled trials (RCTs) systematically assessed the therapeutic effect and tolerability of melatonin for TD in schizophrenia. METHODS: A computerized and systematical search of both Chinese (Wanfang Data, Chinese National Knowledge Infrastructure (CNKI), SINOMED) and English (PubMed, PsycINFO, Embase, Cochrane Library databases) databases, from their inception until June 8, 2017, was conducted by two independent authors...
June 25, 2017: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/28765686/inconsistency-between-univariate-and-multiple-logistic-regressions
#11
Hongyue Wang, Jing Peng, Bokai Wang, Xiang Lu, Julia Z Zheng, Kejia Wang, Xin M Tu, Changyong Feng
Logistic regression is a popular statistical method in studying the effects of covariates on binary outcomes. It has been widely used in both clinical trials and observational studies. However, the results from the univariate regression and from the multiple logistic regression tend to be conflicting. A covariate may show very strong effect on the outcome in the multiple regression but not in the univariate regression, and vice versa. These facts have not been well appreciated in biomedical research. Misuse of logistic regression is very prevalent in medical publications...
April 25, 2017: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/28765685/factitious-disorder-a-rare-cause-for-unexplained-epistaxis
#12
Soumitra DAS, Shabna Mohammed, Nimisha Doval, Arjun Kartha
Epistaxis or nasal bleeding is a common condition which may be severe enough to warrant an urgent medical or surgical treatment. Factitious epistaxis is a rare entity. Due to a lack of exposure in complex behavioral issues during undergraduate training, it is quite natural on the part of a surgeon to miss the underlying emotional phenomena. Here, we present a case of factitious disorder which presented to the surgical causality with nasal bleeding. After proper evaluation and liaison with the department of otorhinolaryngology, we were able to manage the patient with antidepressants and cognitive behavioral therapy...
April 25, 2017: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/28765684/strategic-mental-health-planning-and-its-practice-in-china-retrospect-and-prospect
#13
EDITORIAL
Bin Xie
No abstract text is available yet for this article.
April 25, 2017: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/28765683/the-current-situations-and-needs-of-mental-health-in-china
#14
EDITORIAL
Norman Sartorius
No abstract text is available yet for this article.
April 25, 2017: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/28765682/objectives-of-china-and-the-global-mental-health-work-plan
#15
Xiangdong Wang
No abstract text is available yet for this article.
April 25, 2017: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/28765681/efficacy-and-metabolic-influence-on-blood-glucose-and-serum-lipid-of-ziprasidone-in-the-treatment-of-elderly-patients-with-first-episode-schizophrenia
#16
Jing Chen, Xingen Pan, Mincai Qian, Shoukai Yang
BACKGROUND: As the age of the population in China rises, the occurrence of first-episode of schizophrenia in elderly persons is also gradually increasing. However, studies examining selection of therapeutic drugs for this population are relatively few. OBJECTIVE: To examine the therapeutic efficacy and metabolic influence on blood-glucose and serum lipid of ziprasidone in the treatment of elderly patients with first-episode schizophrenia. METHODS: Using randomized grouping, 38 elderly patients with first-episode schizophrenia were randomly divided into the ziprasidone treatment group (i...
April 25, 2017: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/28765680/a-study-of-the-characteristics-of-alexithymia-and-emotion-regulation-in-patients-with-depression
#17
Hao Zhang, Qing Fan, Yan Sun, Jianyin Qiu, Lisheng Song
BACKGROUND: Even though patients with depression often show significant alexithymia, the underlying mechanism of their alexithymia remains unclear. Furthermore, few experimental studies have explored their ability to regulate emotions. OBJECTIVE: To explore the characteristics of alexithymia in patients with depression, and the relationship of depressive symptoms, alexithymia and emotion regulation. METHODS: A total of 36 patients with depression and 31 healthy controls were enrolled...
April 25, 2017: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/28765679/placement-instability-among-young-people-removed-from-their-original-family-and-the-likely-mental-health-implications
#18
Simon Rice, Sue Cotton, Kristen Moeller-Saxone, Cathrine Mihalopoulos, Anne Magnus, Carol Harvey, Cathy Humphreys, Stephen Halperin, Angela Scheppokat, Patrick McGorry, Helen Herrman
BACKGROUND: Young people in out-of-home care are more likely to experience poorer mental and physical health outcomes related to their peers. Stable care environments are essential for ameliorating impacts of disruptive early childhood experiences, including exposure to psychological trauma, abuse and neglect. At present there are very few high quality data regarding the placement stability history of young people in out-of-home care in Australia or other countries. OBJECTIVES: To undertake the first systematic census of background, care type and placement stability characteristics of young people living in the out-of-home care sector in Australia...
April 25, 2017: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/28765678/factors-related-to-acute-anxiety-and-depression-in-inpatients-with-accidental-orthopedic-injuries
#19
Hui Wu, Fang Zhang, Wenhong Cheng, Ying Lin, Qian Wang
BACKGROUND: Those injured in accidents commonly have strong emotional reactions to their situation. However, despite the large number of patients who are admitted to general hospitals each year for orthopedic injuries due to an accident, research focusing on psychological disorders due to these injuries is lacking. OBJECTIVE: To investigate the presentation and factors related to depression and acute anxiety among inpatients being treated for injury on a Trauma Orthopedics Unit...
April 25, 2017: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/28765677/efficacy-towards-negative-symptoms-and-safety-of-repetitive-transcranial-magnetic-stimulation-treatment-for-patients-with-schizophrenia-a-systematic-review
#20
Junjie Wang, Yingqun Zhou, Hong Gan, Jiaoyan Pang, Hui Li, Jijun Wang, Chunbo Li
BACKGROUND: Negative symptoms are one of the most difficult areas in the treatment of schizophrenia because antipsychotics are often less effective towards them. Repetitive transcranial magnetic stimulation (rTMS) is a new technique for cerebral cortex stimulation and is believed to be a safe and promising method for the treatment of mental disorders. As the clinical research and new treatment models have increased in recent years, the efficacy towards negative symptoms and safety evaluation of rTMS treatment should also be updated...
April 25, 2017: Shanghai Archives of Psychiatry
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