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Wounds: a Compendium of Clinical Research and Practice

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https://www.readbyqxmd.com/read/30212375/insulated-offloading-provides-offloading-protection-and-enhanced-skin-perfusion
#1
Charles A Andersen, Mario Ponticello, Nicole Byerley, Valerie Marmolejo
INTRODUCTION: Locally and neurally mediated vasodilation of the cutaneous vasculature has been shown to occur in response to locally and systemically applied heat stresses. The resultant shunting of blood to the periphery can be upwards of 7 L/min to 8 L/min when profound heat stresses are applied. The increased cutaneous circulation from local heat stress may benefit extremities afflicted with a wound or area of compromised arterial supply. Insulating the extremity also may increase local cutaneous perfusion...
August 16, 2018: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/30212374/negative-pressure-wound-therapy-of-open-abdomen-and-definitive-closure-techniques-after-decompressive-laparotomy-a-single-center-observational-prospective-study
#2
Mircea Muresan, Simona Muresan, Klara Brinzaniuc, Daniela Sala, Radu Neagoe
INTRODUCTION: Open abdomen is a concept that was developed especially in relation to abdominal compartment syndrome (ACS). OBJECTIVE: This study presents the evolution and complications related to the management of the open abdomen after decompressive laparotomy, using a standardized method based on negative pressure wound therapy (NPWT). MATERIALS AND METHODS: This observational prospective study conducted over a 9-month period included 19 patients who underwent decompressive laparotomies for ACS...
August 13, 2018: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/30212373/soft-tissue-coverage-of-complex-periprosthetic-defects-in-patients-with-total-knee-arthroplasty-analysis-of-factors-that-influence-reconstructive-and-functional-outcomes
#3
James M Economides, Michael V DeFazio, Kayvon Golshani, Mark Cinque, Ersilia L Anghel, Chrisovalantis Lakhiani, Rex Hung, Christopher E Attinger, Karen K Evans
INTRODUCTION: Wound breakdown following total knee arthroplasty (TKA) increases the risk of device exposure, infection, and major amputation. Although a variety of options to facilitate coverage of compromised knee joint prostheses exist, the relative safety, efficacy, and functional impact of each has not been determined. OBJECTIVE: This study aims to identify those perioperative factors that influence reconstructive and functional outcomes in patients with periprosthetic TKA defects...
July 30, 2018: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/30212371/extract-of-berula-angustifolia-l-mertens-enhances-wound-healing-in-streptozotocin-induced-diabetic-rats
#4
Negin Sanaei, Rahim Mohammadi, Abbas Raisi, Leila Zarei
INTRODUCTION: Diabetes-impaired wound healing and other tissue abnormalities are considered to be a major concern. OBJECTIVE: The aim of this study is to assess the wound healing activity of the methanolic extracts of Berula angustifolia leaves. MATERIALS AND METHODS: Seven- week-old male Wistar rats with diabetes induced by streptozotocin injection were randomized into 5 groups of 6 rats based on allocated treatment. Wounds were created by an excision-based or incision-based wound model...
June 25, 2018: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/30212360/retracted-degree-of-the-hazards-of-silver-containing-dressings-on-mrsa-infected-wounds-in-sprague-dawley-and-streptozotocin-induced-diabetic-rats
#5
Eui Dong Yeo, Su Ah Yoon, Seong Rok Oh, Young Suk Choi, Young Koo Lee
The Editor and Publisher regretfully have to retract the following two publications due to faulty study design.
September 2018: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/30212359/retracted-comparison-of-dna-damage-and-apoptosis-induced-by-silver-nanoparticle-containing-dressing-materials-during-wound-healing
#6
Young Suk Choi, Heui-Chul Gwak, Jae Keun Park, Ji Yun Lim, Eui Dong Yeo, Eunseok Park, Junyong Kim, Young Koo Lee
The Editor and Publisher regretfully have to retract the following two publications due to faulty study design.
September 2018: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/30183663/study-on-comparison-of-dna-damage-and-apoptosis-is-too-flawed-to-be-clinically-relevant
#7
Linda Benskin
No abstract text is available yet for this article.
September 2018: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/30212370/implantable-nanomedical-scaffold-facilitates-healing-of-chronic-lower-extremity-wounds
#8
Matthew J Regulski, Matthew R MacEwan
BACKGROUND: Chronic, nonhealing wounds are a growing health care problem in the United States, affecting more than 6.5 million patients annually. OBJECTIVE: This retrospective study evaluates the clinical efficacy and utility of an implantable nanomedical scaffold in the treatment of chronic, nonhealing lower extremity wounds in patients with multiple comorbidities. MATERIALS AND METHODS: Data from patients with chronic wounds that had persisted for ≥ 4 weeks and were unresponsive to existing advanced wound care modalities were included in the study...
August 2018: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/30212369/a-patient-centered-remote-therapy-monitoring-program-focusing-on-increased-adherence-to-wound-therapy-a-large-cohort-study
#9
Leah Griffin, Laura M Leyva Casillas
OBJECTIVE: This retrospective study of 510 patients receiving negative pressure wound therapy (NPWT) in a home care setting examines the relationship between remote therapy monitoring (RTM) and patient adherence, as well as determines the impact of patient adherence on wound progression. MATERIALS AND METHODS: Adherence to treatment was continuously monitored via RTM, and patients with therapy usage < 16 hours in 1 day received an adherence call. Repeated failures to reach a noncompliant patient led to an escalation call to the caregiver to discuss treatment...
August 2018: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/30212368/two-cases-of-severe-erosive-pustular-dermatosis-mimicking-infection
#10
Ryan S Din, William G Tsiaras, Arash Mostaghimi
INTRODUCTION: Erosive pustular dermatosis of the scalp (EPDS) is a noninfectious inflammatory disorder characterized by pustules, erosions, ulcerations, and crusted erythematous plaques that is often associated with mechanical or chemical trauma. While its appearance may mimic infection, its etiology is thought to have an autoimmune component based on responsiveness to immunomodulators. CASE REPORT: Herein, the authors present 2 cases of EPDS that were initially treated as primary infections...
August 2018: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/30212367/surgical-site-infections-related-to-esbl-pathogens-post-colon-surgery
#11
Luis Oms, Eliana Kalakouti, Constantinos Simillis, Gianluca Pellino, Nabeela Mughal, Oliver Warren, Sarah Mills, Emile Tan, Christos Kontovounisios, Paris P Tekkis
No abstract text is available yet for this article.
August 2018: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/30212366/the-role-of-negative-pressure-wound-therapy-in-managing-chinese-patients-with-wound-derived-acute-severe-illness
#12
Zhi Wang, Ming Bai, Ang Zeng, Zhifei Liu, Ru Zhao, Xiaojun Wang
INTRODUCTION: Resulting mostly from major injury or infection, severe acute wounds are often accompanied by septic shock or multiple organ failure and associated with high disability and mortality rates. In managing Chinese patients with wound-derived acute severe illnesses, salvage treatment in the emergency department has traditionally prioritized life support and protection of vital organs before wound repair. OBJECTIVE: This retrospective review evaluated the outcomes of patients with wound-derived acute severe illness who were treated with a new salvage protocol that combined proactive wound care with simultaneous life-support measures...
August 2018: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/30212365/efficacy-of-dehydrated-human-amniotic-membrane-allograft-for-the-treatment-of-severe-extravasation-injuries-in-preterm-neonates
#13
Vita Boyar, Colleen Galiczewski
INTRODUCTION: A peripheral intravenous (PIV) catheter is placed in 60% to 70% of neonatal intensive care unit (NICU) infants. Extravasation injuries occur in 18% to 33%, with 70% in neonates < 27 weeks of gestational age. Despite such frequent use of PIV therapy, evidence on best practice, injury prevention, management, and treatment of extravasations is lacking. OBJECTIVE: This case series of 4 neonatal patients describes the experience and efficacy of using a dehydrated human amniotic membrane allograft (dHAMA) in the treatment of severe extravasation injuries...
August 2018: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/30212364/is-pash-syndrome-a-biofilm-disease-a-case-series-and-review-of-the-literature
#14
Joey Karim Ead, Robert J Snyder, Jaime Wise, Cherison Cuffy, Hamed Jafary, Karen Fischborn
INTRODUCTION: When occurring together, pyoderma gangrenosum, severe acne, and hidradenitis suppurativa have been described as PASH syndrome. Due to the chronic autoinflammatory state existing in affected patients, PASH syndrome has been attributed to the dysregulation of wound healing. CASE REPORTS: Two cases are presented that demonstrate the paradigmatic clinical features of PASH syndrome and its potential link as an expanding spectrum of bacterial biofilm disorder...
August 2018: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/30102238/inpatient-and-outpatient-wound-treatment-recommendations-assessing-use-of-negative-pressure-wound-therapy-systems-or-oxidized-regenerated-cellulose-orc-collagen-silver-orc-dressings
#15
Andrew Applewhite, Saeed A Chowdhry, Michael Desvigne, Allen Gabriel, Rosemary Hill, Mary Anne Obst, Dawn Shepherd, Marcus Speyrer, Terry Treadwell, Lindsey Waddell
The increase in wound prevalence means more patients with wounds are being transferred through care settings than ever before. Although the goals of therapy may be the same in both settings, wound care therapies and dressings differ in availability and appropriateness for each setting. Negative pressure wound therapy (NPWT) modalities and oxidized regenerated cellulose (ORC)/collagen (C)/silver-ORC dressings are available in both inpatient and outpatient care settings, but (to-date) lack comprehensive information regarding best practices in transitioning use of these therapies between various care settings...
August 2018: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/30059343/cost-effectiveness-of-a-platelet-rich-plasma-preparation-technique-for-clinical-use
#16
Mohamad Shariff A Hamid
INTRODUCTION: Despite limited clinical evidence, platelet-rich plasma (PRP) is currently used for the treatment of various soft tissue injuries, but optimal use of PRP has yet to be determined. In many instances, PRP is prepared using commercial devices that lack standardized preparation techniques and consistent quality of the PRP produced. OBJECTIVE: The aim of this study is to explore a simple, easy, economical method of PRP preparation that is practical for clinical use...
July 2018: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/30059342/plasma-angiotensin-converting-enzyme-levels-in-patients-with-keloids-and-or-hypertension
#17
Jacob Stewart, Donald A Glass 2nd
INTRODUCTION: Keloidal scarring is associated with hypertension and its pathogenesis remains poorly understood. The role of angiotensin-converting enzyme (ACE) in both hypertensive and fibrotic conditions suggests ACE may be a common mechanism for the pathogenesis of both hypertension and keloids. OBJECTIVE: This paper aims to investigate the possible underlying role of ACE in keloid pathogenesis. MATERIALS AND METHODS: Plasma samples were collected from participants with and without keloids...
July 2018: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/30059341/fournier-s-gangrene-does-not-spare-young-adults
#18
Danijela Semenič, Petra Kolar
INTRODUCTION: Fournier's gangrene is a rare but severe form of necrotizing fasciitis, primarily affecting the perianal, genital, and perineal regions. It is a rapidly progressive disease and can be potentially fatal; therefore, it should be treated as an emergency. CASE REPORT: Presented herein is the case of a 30-year-old man, without significant medical history, who presented to general surgery with complaints of swelling and pain in the gluteal area. The patient underwent emergency surgery on the day of admission to the emergency department where excessive fasciectomy and necrectomy were performed; broad-spectrum parenteral antibiotic therapy also was administered...
July 2018: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/30059340/rare-presentation-of-squamous-cell-carcinoma-of-the-foot-in-a-noncompliant-hiv-patient
#19
Shelly D Sedberry, Michael I Gazes, Elizabeth Zellner, Steven D Vyce
INTRODUCTION: Squamous cell carcinoma (SCC) is most commonly found on sun-damaged skin and less often occurs on the toes and feet. CASE REPORT: A 41-year-old man with a history of human immunodeficiency virus and asthma, who had received highly active antiretroviral therapy for 7 years while incarcerated, presented to the emergency department with a primary SCC of the left foot with inguinal lymph node metastasis. The patient underwent a left foot transmetatarsal amputation; due to noncompliance, he underwent a below-the-knee amputation 17 days later as a result of surgical findings and extent of infection...
July 2018: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/30059339/chlorhexidine-patient-bathing-prior-to-arthroplasty
#20
Laura Bolton
No abstract text is available yet for this article.
July 2018: Wounds: a Compendium of Clinical Research and Practice
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