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NPJ Primary Care Respiratory Medicine

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https://www.readbyqxmd.com/read/30401831/imp-2-art-systematic-review-of-education-for-healthcare-professionals-implementing-supported-self-management-for-asthma
#1
REVIEW
Nicola McCleary, Amanda Andrews, Audrey Buelo, Mireille Captieux, Susan Morrow, Sharon Wiener-Ogilvie, Monica Fletcher, Liz Steed, Stephanie J C Taylor, Hilary Pinnock
Despite a robust evidence base for its effectiveness, implementation of supported self-management for asthma is suboptimal. Professional education is an implementation strategy with proven effectiveness, though the specific features linked with effectiveness are often unclear. We performed a systematic review of randomised controlled trials and controlled clinical trials (published from 1990 and updated to May 2017 using forward citation searching) to determine the effectiveness of professional education on asthma self-management support and identify features of effective initiatives...
November 6, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/30385757/cross-sectional-study-assessing-the-performance-of-the-arabic-translated-childhood-asthma-control-test
#2
Majid AlTeneiji, Alia AlKalbani, Huda Nasser, Durdana Iram, Afaf Alblooshi, Hassib Narchi
The standard Arabic version of the Childhood Asthma Control Test (C-ACT) has never been previously evaluated in Arab countries. We studied its correlation in Arabic speaking children in the United Arab Emirates (UAE), with both the GINA assessment of asthma control and the resulting changes in asthma management. The Arabic C-ACT was completed by the children or by their parents when needed. A GINA based level of asthma control score was assigned by their managing physician. The correlation between the different cut- scores of the C-ACT and GINA were studied...
November 1, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/30367067/diagnostic-value-of-signs-symptoms-and-diagnostic-tests-for-diagnosing-pneumonia-in-ambulant-children-in-developed-countries-a-systematic-review
#3
REVIEW
Marjolein J C Schot, Anne R J Dekker, Wesley G Giorgi, Rogier M Hopstaken, Niek J de Wit, Theo J M Verheij, Jochen W L Cals
Identifying a child with pneumonia in the large group of children with acute respiratory tract infections can be challenging for primary care physicians. Knowledge on the diagnostic value of specific signs and symptoms may guide future decision rules and guidelines for clinicians. We aimed to identify and systematically review available evidence for the diagnostic value of signs, symptoms, and additional tests to diagnose pneumonia in children in an ambulatory setting in developed countries. We conducted a systematic review, searching in the electronic databases of PubMed and Embase...
October 26, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/30356047/prospective-observational-cohort-study-of-symptom-control-prediction-in-paediatric-asthma-by-using-the-royal-college-of-physicians-three-questions
#4
Glen Andrews, David K H Lo, Matthew Richardson, Andrew Wilson, Erol A Gaillard
The Royal College of Physicians three questions (RCP3Q) is widely used for assessing asthma control within primary care in the UK, despite limited evidence in children. This study compared the RCP3Q as a tool for assessing asthma control in children (5-16 years) against the validated Asthma Control Test (ACT), Childhood Asthma Control Test (C-ACT), and Mini-Paediatric Quality of Life Questionnaire (MiniPAQLQ). We conducted a prospective observational cohort study involving children from eight primary care practices in Leicestershire...
October 24, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/30305634/a-non-randomised-controlled-pilot-study-of-clinical-pharmacist-collaborative-intervention-for-community-dwelling-patients-with-copd
#5
Vicki Hunt, Dave Anderson, Richard Lowrie, Colette Montgomery Sardar, Susan Ballantyne, Graeme Bryson, John Kyle, Peter Hanlon
UK, home-based patients with COPD receive specialist care from respiratory physicians, nurses, and general practitioners (GPs), but increasing complexity of therapeutic options and a GP/Nurse workforce crisis suggests merit in testing the role of home visits by a clinical pharmacist. We conducted a non-randomised intervention study with a contemporaneous comparator group, in Glasgow (Scotland). A clinical pharmacist (working closely with a consultant respiratory physician) visited patients with COPD living at home, assessing respiratory and other co-morbid conditions, and medicines then, with patient approval, agreed treatment modifications with a consultant physician...
October 10, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/30301889/primary-care-cohort-study-in-the-sequence-of-diagnosing-chronic-respiratory-diseases-and-prescribing-inhaled-corticosteroids
#6
Ilja Geraets, Tjard Schermer, Janwillem W H Kocks, Reinier Akkermans, Erik Bischoff, Lisette van den Bemt
To prevent unnecessary use of inhaled corticosteroids (ICS), ICS treatment should only be started when the diagnostic process of asthma and COPD is completed. Little is known about the chronological order between these diagnoses and the start of ICS. We performed a retrospective cohort study, based on electronic medical records of 178 Dutch general practices, to explore the temporal relations between starting continuous use of ICS and receiving a diagnosis of asthma and/or COPD. The database included information of patients who were registered with a diagnosis of asthma and/or COPD in one of the practices during January 1, 2012 and December 31, 2013...
October 9, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/30266978/population-based-study-of-lama-monotherapy-effectiveness-compared-with-laba-lama-as-initial-treatment-for-copd-in-primary-care
#7
Miriam Barrecheguren, Mónica Monteagudo, Marc Miravitlles
This epidemiological study aimed to describe and compare the characteristics and outcomes of COPD patients starting treatment with a long-acting anti-muscarinic (LAMA) or a combination of a long-acting beta-2 agonist (LABA)/LAMA in primary care in Catalonia (Spain) over a one-year period. Data were obtained from the Information System for the Development in Research in Primary Care (SIDIAP), a population database containing information of 5.8 million inhabitants (80% of the population of Catalonia). Patients initiating treatment with a LAMA or LABA/LAMA in 2015 were identified, and information about demographic and clinical characteristics was collected...
September 28, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/30232329/insights-into-frequent-asthma-exacerbations-from-a-primary-care-perspective-and-the-implications-of-uk-national-review-of-asthma-deaths-recommendations
#8
Jieqiong Freda Yang, Rekha Chaudhuri, Neil C Thomson, Nitish Ramparsad, Hugh O'Pray, Stephen Barclay, Sean MacBride-Stewart, Craig McCallum, Varun Sharma, Charles McSharry, Dianne Murray, Malcolm Shepherd, Wai-Ting Nicola Lee
The United Kingdom National Review of Asthma Deaths (NRAD) recommends that patients who require ≥3 courses of oral corticosteroids (OCS) for exacerbations in the past year or those on British Thoracic Society (BTS) Step 4/5 treatment must be referred to a specialist asthma service. The aim of the study was to identify the proportion of asthma patients in primary care that fulfil NRAD criteria for specialist referral and factors associated with frequent exacerbations. A total of 2639 adult asthma patients from 10 primary care practices in Glasgow, UK were retrospectively studied between 2014 and 2015...
September 19, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/30213945/a-patient-centric-analysis-to-identify-key-influences-in-allergic-rhinitis-management
#9
Biljana Cvetkovski, Rachel Tan, Vicky Kritikos, Kwok Yan, Elizabeth Azzi, Pamela Srour, Sinthia Bosnic-Anticevich
Allergic rhinitis (AR) is increasingly becoming a patient self-managed disease. Just under 70% of patients purchasing pharmacotherapy self-select their treatment with no health-care professional intervention often resulting in poor choices, leading to suboptimal management and increased burden of AR on the individual and the community. However, no decision is made without external, influencing forces. This study aims to determine the key influences driving patients' decision-making around AR management. To accomplish this aim, we utilised a social network theory framework to map the patient's AR network and identify the strength of the influences within this network...
September 13, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/30202023/real-world-retrospective-cohort-study-arctic-shows-burden-of-comorbidities-in-swedish-copd-versus-non-copd-patients
#10
Björn Ställberg, Christer Janson, Kjell Larsson, Gunnar Johansson, Konstantinos Kostikas, Jean-Bernard Gruenberger, Florian S Gutzwiller, Leif Jorgensen, Milica Uhde, Karin Lisspers
This study aimed to generate real-world evidence to assess the burden of comorbidities in COPD patients, to effectively manage these patients and optimize the associated healthcare resource allocation. ARCTIC is a large, real-world, retrospective cohort study conducted in Swedish COPD patients using electronic medical record data collected between 2000 and 2014. These patients were studied for prevalence of various comorbidities and for association of these comorbidities with exacerbations, mortality, and healthcare costs compared with an age-, sex-, and comorbidities-matched non-COPD reference population...
September 10, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/30150639/systematic-literature-review-and-meta-analysis-of-us-approved-lama-laba-therapies-versus-tiotropium-in-moderate-to-severe-copd
#11
MeiLan K Han, Riju Ray, Jason Foo, Chaienna Morel, Beth Hahn
Dual bronchodilator maintenance therapy may benefit patients with moderate-to-severe chronic obstructive pulmonary disease (COPD) versus long-acting muscarinic antagonist (LAMA) monotherapy. The efficacy and safety of US-approved LAMA/long-acting beta-agonist (LABA) combinations versus tiotropium (TIO), a LAMA, were assessed. This systematic review and meta-analysis (GSK: 206938), conducted in MEDLINE, MEDLINE In-process, and EMBASE following Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines, identified randomized clinical trials (>8 weeks) in moderate-to-severe COPD (per Global Initiative for Chronic Obstructive Lung Disease guidelines), receiving LAMA/LABA or TIO...
August 27, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/30108224/exercise-induced-bronchoconstriction-prevalence-pathophysiology-patient-impact-diagnosis-and-management
#12
REVIEW
Bhumika Aggarwal, Aruni Mulgirigama, Norbert Berend
Exercise-induced bronchoconstriction (EIB) can occur in individuals with and without asthma, and is prevalent among athletes of all levels. In patients with asthma, symptoms of EIB significantly increase the proportion reporting feelings of fearfulness, frustration, isolation, depression and embarrassment compared with those without symptoms. EIB can also prevent patients with asthma from participating in exercise and negatively impact their quality of life. Diagnosis of EIB is based on symptoms and spirometry or bronchial provocation tests; owing to low awareness of EIB and lack of simple, standardised diagnostic methods, under-diagnosis and mis-diagnosis of EIB are common...
August 14, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/30097575/the-physical-mental-and-social-impact-of-copd-in-a-population-based-sample-results-from-the-longitudinal-aging-study-amsterdam
#13
Frits M E Franssen, Dionne E Smid, Dorly J H Deeg, Martijn Huisman, Jan Poppelaars, Emiel F M Wouters, Martijn A Spruit
Chronic obstructive pulmonary disease (COPD) is associated with substantial health impact that may already become apparent in early disease. This study aims to examine the features of subjects with COPD in a Dutch population-based sample and compare their physical status, mental status, and social status to non-COPD subjects. This study made use of Longitudinal Aging Study Amsterdam (LASA) data. Demographics, clinical characteristics, self-reported diseases, post-bronchodilator spirometry, physical, mental, and social status were assessed...
August 10, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/30050083/a-review-of-asthma-care-in-50-general-practices-in-bedfordshire-united-kingdom
#14
Mark L Levy, Fiona Garnett, Adedayo Kuku, Inna Pertsovskaya, Eddie McKnight, John Haughney
The United Kingdom (UK) National Review of Asthma Deaths (NRAD) (2011-2014) identified a number of contributory risk factors which had not previously been recognized by those caring for people with asthma. Only one of the 19 NRAD recommendations has so far been implemented nationally, and that only partially, and as yet systems are not in place to identify patients at risk of attacks and dying from asthma. In 2015/2016 Bedfordshire Clinical Commissioning Group (CCG) in England, UK, initiated a quality asthma audit of people with asthma to identify some of the risk factors identified in the NRAD report with the aim of optimizing patient care...
July 26, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/30038222/applying-uk-real-world-primary-care-data-to-predict-asthma-attacks-in-3776-well-characterised-children-a-retrospective-cohort-study
#15
Steve W Turner, Clare Murray, Mike Thomas, Annie Burden, David B Price
Current understanding of risk factors for asthma attacks in children is based on studies of small but well-characterised populations or pharmaco-epidemiology studies of large but poorly characterised populations. We describe an observational study of factors linked to future asthma attacks in large number of well-characterised children. From two UK primary care databases (Clinical Practice Research Datalink and Optimum Patient Care research Database), a cohort of children was identified with asthma aged 5-12 years and where data were available for ≥2 consecutive years...
July 23, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/30026587/high-health-gain-patients-with-asthma-a-cross-sectional-study-analysing-national-scottish-data-sets
#16
Mome Mukherjee, Bright I Nwaru, Ireneous Soyiri, Ian Grant, Aziz Sheikh
Studies have shown that a small proportion of patients have particularly high needs and are responsible for disproportionally high disease burden. Estimates suggest that 2-5% of patients are high users of healthcare for their health gain. Such patients in Scotland are referred to as high health gain (HHG) patients. We wanted to investigate if there were HHG individuals with asthma in Scotland. We analysed data from the Scottish Health Survey (2010-11), and primary and National Health Survey (NHS) secondary healthcare and administrative data sets (2011-12)...
July 19, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/30022059/-tossing-a-coin-defining-the-excessive-use-of-short-acting-beta-2-agonists-in-asthma-the-views-of-general-practitioners-and-asthma-experts-in-primary-and-secondary-care
#17
Shauna McKibben, Andy Bush, Mike Thomas, Chris Griffiths
The National Review of Asthma Deaths (NRAD) identified high prescribing of short-acting beta2 -agonists (SABAs) as a key factor in over 40% of deaths. We interviewed asthma experts from both a hospital background (n = 5) and a primary care background (n = 8), and general practitioners delivering asthma care (n = 8), to identify how SABA use is defined and perceived. We identified disparity in how acceptable SABA use is defined, ranging from 0.5 (100 doses/year) to 12 SABA inhalers (2400 doses/year), and complacency in the perception that over-use did not represent a marker for risk of asthma death...
July 18, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/29955120/author-correction-recurrent-lower-respiratory-illnesses-among-young-children-in-rural-kyrgyzstan-overuse-of-antibiotics-and-possible-under-diagnosis-of-asthma-a-qualitative-fresh-air-study
#18
Marianne Stubbe Østergaard, Jesper Kjærgaard, Mette Marie Kristensen, Susanne Reventlow, Anja Poulsen, Elvira Isaeva, Azamat Akylbekov, Talant Sooronbaev
The original version of this Article contained an error in the spelling of the author Mette Marie Kristensen, which was incorrectly given as Mette-Marie Kristensen. The affiliation details for Mette Marie Kristensen were also incorrect in this Article. This has now been corrected in both the PDF and HTML versions of this article.
June 28, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/29950601/personalising-adherence-enhancing-interventions-using-a-smart-inhaler-in-patients-with-copd-an-exploratory-cost-effectiveness-analysis
#19
Job F M van Boven, Breda Cushen, Imran Sulaiman, Garrett Greene, Elaine MacHale, Matshediso C Mokoka, Frank Doyle, Richard B Reilly, Kathleen Bennett, Richard W Costello
Four inhaler adherence clusters have been identified using the INCA audio device in COPD patients: (1) regular use/good technique, (2) regular use/frequent technique errors, (3) irregular use/good technique, and (4) irregular use/frequent technique errors. Their relationship with healthcare utilization and mortality was established, but the cost-effectiveness of adherence-enhancing interventions is unknown. In this exploratory study, we aimed to estimate the potential cost-effectiveness of reaching optimal adherence in the three suboptimal adherence clusters, i...
June 27, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/29934520/breathlessness-and-sexual-activity-in-older-adults-the-australian-longitudinal-study-of-ageing
#20
Magnus Ekström, Miriam J Johnson, Bridget Taylor, Mary Luszcz, Pia Wohland, Diana H Ferreira, David C Currow
Sexual activity is important to older adults (65 + ). Breathlessness affects about 25% of older adults but impact on sexual activity is unknown. We evaluated the relationships between breathlessness and sexual inactivity and self-reported health among older community-dwelling adults in the Australian Longitudinal Study of Ageing. Associations between self-reported breathlessness (hurrying on level ground or walking up a slight hill) at baseline, self-reported sexual activity, overall health and health compared to people of the same age were explored using logistic regression at baseline and 2 years, adjusted for potential confounders (age, sex, marital status, smoking status and co-morbidities)...
June 22, 2018: NPJ Primary Care Respiratory Medicine
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