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NPJ Primary Care Respiratory Medicine

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https://www.readbyqxmd.com/read/29955120/author-correction-recurrent-lower-respiratory-illnesses-among-young-children-in-rural-kyrgyzstan-overuse-of-antibiotics-and-possible-under-diagnosis-of-asthma-a-qualitative-fresh-air-study
#1
Marianne Stubbe Østergaard, Jesper Kjærgaard, Mette Marie Kristensen, Susanne Reventlow, Anja Poulsen, Elvira Isaeva, Azamat Akylbekov, Talant Sooronbaev
The original version of this Article contained an error in the spelling of the author Mette Marie Kristensen, which was incorrectly given as Mette-Marie Kristensen. The affiliation details for Mette Marie Kristensen were also incorrect in this Article. This has now been corrected in both the PDF and HTML versions of this article.
June 28, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/29950601/personalising-adherence-enhancing-interventions-using-a-smart-inhaler-in-patients-with-copd-an-exploratory-cost-effectiveness-analysis
#2
Job F M van Boven, Breda Cushen, Imran Sulaiman, Garrett Greene, Elaine MacHale, Matshediso C Mokoka, Frank Doyle, Richard B Reilly, Kathleen Bennett, Richard W Costello
Four inhaler adherence clusters have been identified using the INCA audio device in COPD patients: (1) regular use/good technique, (2) regular use/frequent technique errors, (3) irregular use/good technique, and (4) irregular use/frequent technique errors. Their relationship with healthcare utilization and mortality was established, but the cost-effectiveness of adherence-enhancing interventions is unknown. In this exploratory study, we aimed to estimate the potential cost-effectiveness of reaching optimal adherence in the three suboptimal adherence clusters, i...
June 27, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/29934520/breathlessness-and-sexual-activity-in-older-adults-the-australian-longitudinal-study-of-ageing
#3
Magnus Ekström, Miriam J Johnson, Bridget Taylor, Mary Luszcz, Pia Wohland, Diana H Ferreira, David C Currow
Sexual activity is important to older adults (65 + ). Breathlessness affects about 25% of older adults but impact on sexual activity is unknown. We evaluated the relationships between breathlessness and sexual inactivity and self-reported health among older community-dwelling adults in the Australian Longitudinal Study of Ageing. Associations between self-reported breathlessness (hurrying on level ground or walking up a slight hill) at baseline, self-reported sexual activity, overall health and health compared to people of the same age were explored using logistic regression at baseline and 2 years, adjusted for potential confounders (age, sex, marital status, smoking status and co-morbidities)...
June 22, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/29925846/-a-palliative-end-stage-copd-patient-does-not-exist-a-qualitative-study-of-barriers-to-and-facilitators-for-early-integration-of-palliative-home-care-for-end-stage-copd
#4
Charlotte Scheerens, Luc Deliens, Simon Van Belle, Guy Joos, Peter Pype, Kenneth Chambaere
Early integration of palliative home care (PHC) might positively affect people with chronic obstructive pulmonary disease (COPD). However, PHC as a holistic approach is not well integrated in clinical practice at the end-stage COPD. General practitioners (GPs) and community nurses (CNs) are highly involved in primary and home care and could provide valuable perspectives about barriers to and facilitators for early integrated PHC in end-stage COPD. Three focus groups were organised with GPs (n = 28) and four with CNs (n = 28), transcribed verbatim and comparatively analysed...
June 20, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/29925836/identifying-patients-with-asthma-chronic-obstructive-pulmonary-disease-overlap-syndrome-using-latent-class-analysis-of-electronic-health-record-data-a-study-protocol
#5
Mohammad A Al Sallakh, Sarah E Rodgers, Ronan A Lyons, Aziz Sheikh, Gwyneth A Davies
Asthma and chronic obstructive pulmonary disease (COPD) are two common different clinical diagnoses with overlapping clinical features. Both conditions have been increasingly studied using electronic health records (EHR). Asthma-COPD overlap syndrome (ACOS) is an emerging concept where clinical features from both conditions co-exist, and for which, however, there is no consensus definition. Nonetheless, we expect EHR data of people with ACOS to be systematically different from those with "asthma only" or "COPD only"...
June 20, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/29921879/recruitment-of-patients-with-chronic-obstructive-pulmonary-disease-copd-from-the-clinical-practice-research-datalink-cprd-for-research
#6
Jennifer K Quint, Elisabeth Moore, Adam Lewis, Maimoona Hashmi, Kirin Sultana, Mark Wright, Liam Smeeth, Lia Chatzidiakou, Roderic Jones, Sean Beevers, Sefki Kolozali, Frank Kelly, Benjamin Barratt
Databases of electronic health records (EHR) are not only a valuable source of data for health research but have also recently been used as a medium through which potential study participants can be screened, located and approached to take part in research. The aim was to assess whether it is feasible and practical to screen, locate and approach patients to take part in research through the Clinical Practice Research Datalink (CPRD). This is a cohort study in primary care. The CPRD anonymised EHR database was searched to screen patients with Chronic Obstructive Pulmonary Disease (COPD) to take part in a research study...
June 19, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/29867117/facilitators-and-barriers-to-physical-activity-following-pulmonary-rehabilitation-in-copd-a-systematic-review-of-qualitative-studies
#7
REVIEW
Hayley Robinson, Veronika Williams, Ffion Curtis, Christopher Bridle, Arwel W Jones
Pulmonary rehabilitation has short-term benefits on dyspnea, exercise capacity and quality of life in COPD, but evidence suggests these do not always translate to increased daily physical activity on a patient level. This is attributed to a limited understanding of the determinants of physical activity maintenance following pulmonary rehabilitation. This systematic review of qualitative research was conducted to understand COPD patients' perceived facilitators and barriers to physical activity following pulmonary rehabilitation...
June 4, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/29795478/comparison-of-glycopyrronium-versus-tiotropium-on-the-time-to-clinically-important-deteriorations-in-patients-with-copd-a-post-hoc-analysis-of-randomized-trials
#8
Anthony D'Urzo, Giovanni Bader, Steven Shen, Pankaj Goyal, Pablo Altman
Glycopyrronium is a once-daily, inhaled long-acting muscarinic antagonist (LAMA) demonstrating similar efficacy to inhaled tiotropium in patients with moderate-to-severe COPD; however, the benefit of LAMAs on COPD symptoms has been variable. COPD is a progressive disease in which many patients develop an acute or sustained deterioration. Data on the prevention of clinically important deteriorations (CID) using LAMAs are limited. A pooled analysis was performed on four Phase III trials (n = 2936) that compared the efficacy of glycopyrronium (n = 1859) with tiotropium (n = 1077)...
May 24, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/29789607/point-of-care-microspirometry-to-facilitate-the-copd-diagnostic-process-in-primary-care-a-clustered-randomised-trial
#9
Tjard R Schermer, Maria Vatsolaki, Robbert Behr, Joke Grootens, Riet Cretier, Reinier Akkermans, Joke Denis, Patrick Poels, Lisette van den Bemt
We studied if pre-bronchodilator FEV1 /FEV6 determinations with microspirometers by GPs improve the diagnostic process for COPD in a 6-8 month clustered randomised controlled trial in Dutch general practices ( http://www.trialregister.nl : NTR4041). GPs allocated to microspirometry (MI) used COPD-6® microspirometers in patients ≥50 years old with a smoking history and respiratory complaints that could indicate undiagnosed COPD and ask to refer patients for full spirometry if MI was positive (FEV1 /FEV6 <0...
May 22, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/29785053/management-of-children-and-young-people-cyp-with-asthma-a-clinical-audit-report
#10
Mark L Levy, Angela Ward, Sara Nelson
An asthma attack or exacerbation signals treatment failure. Most attacks are preventable and failure to recognize risk of asthma attacks are well recognized as risk factors for future attacks and even death. Of the 19 recommendations made by the United Kingdom National Review of Asthma Deaths (NRAD) (1) only one has been partially implemented-a National Asthma Audit; however, this hasn't reported yet. The Harrow Clinical Commissioning Group (CCG) in London implemented a clinical asthma audit on 291 children and young people aged under 19 years (CYP) who had been treated for asthma attacks in 2016...
May 21, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/29777106/clinical-prediction-models-to-support-the-diagnosis-of-asthma-in-primary-care-a-systematic-review-protocol
#11
L Daines, S McLean, A Buelo, S Lewis, A Sheikh, H Pinnock
Substantial over-diagnosis and under-diagnosis of asthma in adults and children has recently been reported. As asthma is mostly diagnosed in non-specialist settings, a clinical prediction model (CPM) to aid the diagnosis of asthma in primary care may help improve diagnostic accuracy. We aim to systematically identify, describe, compare, and synthesise existing CPMs designed to support the diagnosis of asthma in children and adults presenting with symptoms suggestive of the disease, in primary care settings or equivalent populations...
May 18, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/29662064/the-use-of-electronic-alerts-in-primary-care-computer-systems-to-identify-the-excessive-prescription-of-short-acting-beta-2-agonists-for-people-with-asthma-a-systematic-review
#12
REVIEW
Shauna McKibben, Anna De Simoni, Andy Bush, Mike Thomas, Chris Griffiths
Computers are increasingly used to improve prescribing decisions in the management of long-term conditions however the effects on asthma prescribing remain unclear. We aimed to synthesise the evidence for the use of computerised alerts that identify excessive prescribing of short-acting beta2 -agonists (SABAs) to improve asthma management for people with asthma. MEDLINE, CINAHL, Embase, Cochrane and Scopus databases (1990-2016) were searched for randomised controlled trials using electronic alerts to identify excessive prescribing of SABAs for people with asthma in primary care...
April 16, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/29636473/recurrent-lower-respiratory-illnesses-among-young-children-in-rural-kyrgyzstan-overuse-of-antibiotics-and-possible-under-diagnosis-of-asthma-a-qualitative-fresh-air-study
#13
Marianne Stubbe Østergaard, Jesper Kjærgaard, Mette-Marie Kristensen, Susanne Reventlow, Anja Poulsen, Elvira Isaeva, Azamat Akylbekov, Talant Sooronbaev
Lower respiratory tract illnesses (LRT-illnesses) in children under 5 years (U5s) are a leading cause of morbidity, hospitalisations and mortality worldwide, particularly in low-income countries. It is pertinent to understand possible inconsistent management. This study explored perceptions and practices among caregivers and health professionals on recurrent LRT-illnesses in U5s. Semi-structured interviews with 13 caregivers to U5s with recurrent LRT-illnesses and with 22 primary care health professional interviews in two rural provinces in Kyrgyzstan were triangulated...
April 10, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/29615629/asbestosis-is-prevalent-in-a-variety-of-construction-industry-trades
#14
G I Walters, A S Robertson, P S Bhomra, P S Burge
A diagnosis of asbestosis, which is a long-latency, fibrotic lung disease, has implications for the patient in terms of prognosis, treatment and compensation. Identifying and quantifying asbestos exposure is difficult without a detailed occupational history, and the threshold dose of asbestos required to cause asbestosis is not well understood. We reviewed all cases of asbestosis diagnosed between 2001 and 2016 at the Birmingham Regional NHS Occupational Lung Disease Service to determine the industries and occupations most frequently implicated in causation, in order to help clinicians identify where asbestosis might enter the differential diagnosis for a patient with chronic respiratory symptoms...
April 3, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/29615628/-exacerbation-free-time-to-assess-the-impact-of-exacerbations-in-patients-with-chronic-obstructive-pulmonary-disease-copd-a-prospective-observational-study
#15
L M Boer, E W Bischoff, X Borgijink, J H Vercoulen, R P Akkermans, H A M Kerstjens, W J Assendelft, T R Schermer
COPD exacerbations are commonly quantified as rate per year. However, the total amount of time a patient suffers from exacerbations may be stronger related to his or her disease burden than just counting exacerbation episodes. In this study, we examined the relationship between exacerbation frequency and exacerbation-free time, and their associations with baseline characteristics and health-related quality of life. A total of 166 COPD patients reported symptom changes during 12 months. Symptom-defined exacerbation episodes were correlated to the number of exacerbation-free weeks per year...
April 3, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/29572448/improvement-in-the-management-of-chronic-obstructive-pulmonary-disease-following-a-clinical-educational-program-results-from-a-prospective-cohort-study-in-the-sicilian-general-practice-setting
#16
Rosarita Ferrara, Valentina Ientile, Carlo Piccinni, Alessandro Pasqua, Serena Pecchioli, Andrea Fontana, Umberto Alecci, Riccardo Scoglio, Francesco Magliozzo, Sebastiano Emanuele Torrisi, Carlo Vancheri, Patrizio Vitulo, Giovanna Fantaci, Carmen Ferrajolo, Mario Cazzola, Claudio Cricelli, Achille Patrizio Caputi, Gianluca Trifirò
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disorder of the lungs associated with progressive disability. Although general practitioners (GPs) should play an important role in the COPD management, critical issues have been documented in the primary care setting. The aim of this study was to evaluate the effectiveness of an educational program for the improvement of the COPD management in a Sicilian general practice setting. The effectiveness of the program, was evaluated by comparing 15 quality-of-care indicators developed from data extracted by 33 GPs, at baseline vs...
March 23, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/29523779/agreement-between-hospital-and-primary-care-on-diagnostic-labeling-for-copd-and-heart-failure-in-toronto-canada-a-cross-sectional-observational-study
#17
Michelle Greiver, Frank Sullivan, Sumeet Kalia, Babak Aliarzadeh, Deepak Sharma, Steven Bernard, Christopher Meaney, Rahim Moineddin, David Eisen, Navid Rahman, Tony D'Urzo
Patients with chronic obstructive pulmonary disease (COPD) or heart failure (HF) are frequently cared for in hospital and in primary care settings. We studied labeling agreement for COPD and HF for patients seen in both settings in Toronto, Canada. This was a retrospective observational study using linked hospital-primary care electronic data from 70 family physicians. Patients were 20 years of age or more and had at least one visit in both settings between 1 January 2012 and 31 December 2014. We recorded labeling concordance and associations with clinical factors...
March 9, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/29520001/fostering-the-exchange-of-real-world-data-across-different-countries-to-answer-primary-care-research-questions-an-unlock-study-from-the-ipcrg
#18
Liza Cragg, Siân Williams, Thys van der Molen, Mike Thomas, Jaime Correia de Sousa, Niels H Chavannes
There is growing awareness amongst healthcare planners, providers and researchers of the need to make better use of routinely collected health data by translating it into actionable information that improves efficiency of healthcare and patient outcomes. There is also increased acceptance of the importance of real world research that recruits patients representative of primary care populations and evaluates interventions realistically delivered by primary care professionals. The UNLOCK Group is an international collaboration of primary care researchers and practitioners from 15 countries...
March 8, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/29467461/the-association-of-aspirin-use-with-severity-of-acute-exacerbation-of-chronic-obstructive-pulmonary-disease-a-retrospective-cohort-study
#19
Tadahiro Goto, Mohammad Kamal Faridi, Carlos A Camargo, Kohei Hasegawa
Little is known about the effect of long-term aspirin use on acute severity of COPD. We hypothesized that, in patients hospitalized for acute exacerbation of COPD (AECOPD), long-term aspirin use is associated with lower risks of disease severity (in-hospital death, mechanical ventilation use, and hospital length-of-stay). We conducted a retrospective cohort study using large population-based data from 2012 through 2013. Among 206,686 patients (aged ≥40 years) hospitalized for AECOPD, aspirin users had lower in-hospital mortality (1...
February 21, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/29459619/quality-and-learning-aspects-of-the-first-9000-spirometries-of-the-lifegene-study
#20
Mikaela Qvarfordt, Martin Anderson, Magnus Svartengren
Spirometry requires the patient to cooperate and do the manoeuvre 'right' for reliable results. Algorithms to assess test quality as well as educational recommendations for personnel are defined in guidelines. We compared the quality of forced spirometry tests performed by spirometry technicians with little or no previous experience of spirometry using spirometry systems with different modes of feedback. In both cases, the spirometry technician received general feedback on the screen based on ATS/ERS guidelines, such as 'exhale faster' and 'exhale longer'...
February 19, 2018: NPJ Primary Care Respiratory Medicine
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