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Journal of Food and Drug Analysis

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https://www.readbyqxmd.com/read/28911661/corrigendum-to-biopharmaceutical-potentials-of-prosopis-spp-mimosaceae-leguminosa-j-food-drug-anal-25-2017-187-196
#1
Santhaseelan Henciya, Prabha Seturaman, Arthur Rathinam James, Yi-Hong Tsai, Rahul Nikam, Yang-Chang Wu, Hans-Uwe Dahms, Fang Rong Chang
No abstract text is available yet for this article.
July 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28911660/an-ecofriendly-green-liquid-chromatographic-method-for-simultaneous-determination-of-nicotinamide-and-clindamycin-phosphate-in-pharmaceutical-gel-for-acne-treatment
#2
Fawzia Ibrahim, Asmaa Kamal El-Deen, Samah Abo El Abass, Kuniyoshi Shimizu
A new green micellar liquid chromatographic method was developed and validated for the quantitative estimation of nicotinamide (NICO) and clindamycin phosphate (CLD) in bulk and pharmaceutical gel formulation. The analytes are well resolved in less than 6.0 minutes using micellar mobile phase consisting of 0.10M sodium dodecyl sulfate (SDS), 0.3% triethylamine, and 10% 2-propanol in 0.02M orthophosphoric acid at pH 3.0, running through an Eclipse XDB-C8 column (150 mm×4.6 mm, 5 μm particle size) with flow rate 1...
July 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28911659/the-detoxifying-effects-of-structural-elements-of%C3%A2-persimmon-tannin-on-chinese-cobra-phospholipase-a2-correlated-with-their-structural-disturbing-effects-well
#3
Ying Zhang, Chun-Mei Li
The effects of persimmon tannin (PT) characteristic structural elements on Naja atra phospholipase A2 (PLA2)-induced lethality, myotoxicity, and hemolysis in mice models were determined. In addition, methods including surface plasmon resonance, dynamic light scattering, and Fourier transform infrared spectroscopy were explored to uncover the possible detoxifying mechanisms of PT on snake venom PLA2. Our results revealed that PT characteristic elements (EGCG, ECG, A-type EGCG dimer, and A-type ECG dimer) could neutralize the lethality, myotoxicity, and hemolysis of PLA2...
July 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28911658/identification-of-an-exposure-risk-to-heavy-metals-from-pharmaceutical-grade-rubber-stoppers
#4
Xianghui Li, Pingping Qian
Exposure to low concentrations of heavy metals and metalloids represents a well-documented risk to animal and human health. However, current standards (European Pharmacopeia [EP], United States Pharmacopoeia [USP], International Organization for Standardization [ISO], YBB concerned with rubber closures) only require testing for Zn in pharmaceutical-grade rubber stoppers and then using only pure water as a solvent. We extracted and quantified heavy metals and trace elements from pharmaceutical-grade rubber stoppers under conditions that might occur during the preparation of drugs...
July 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28911657/convenient-uv-spectrophotometric-determination-of-citrates-in-aqueous-solutions-with-applications-in-the-pharmaceutical-analysis-of-oral-electrolyte-formulations
#5
Sylwester Krukowski, Mateusz Karasiewicz, Waclaw Kolodziejski
Herein, we present a convenient method for quantitative spectrophotometric determination of citrate ions in aqueous solutions in the middle-UV range. It involves measuring the absorbance of citric acid at 209 nm under suppressed dissociation at pH < 1.0 in the presence of hydrochloric acid. Validation of the method was performed according to the guidelines of the International Conference on Harmonization. A very good linear dependence of the absorbance on concentration (r(2) = 0.9999) was obtained in a citrate concentration range of 0...
July 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28911656/physicochemical-analysis-and-nonisothermal-kinetic-study-of-sertraline-lactose-binary-mixtures
#6
Faranak Ghaderi, Mahboob Nemati, Mohammad Reza Siahi-Shadbad, Hadi Valizadeh, Farnaz Monajjemzadeh
In the present study the physicochemical stability of sertraline with lactose was evaluated in drug-excipient binary mixtures. Different physicochemical methods such as differential scanning calorimetry (DSC), Fourier-transform infrared spectroscopy, and mass spectrometry were applied to confirm the incompatibility. The final aim of this study was to evaluate the kinetic parameters using a fast and sensitive DSC method. Solid-state kinetic parameters were derived from nonisothermally stressed physical mixtures using different thermal models such as Friedman, Flynn-Wall-Ozawa, and Kissinger-Akahira-Sunose...
July 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28911655/therapeutic-effects-of-d-aspartate-in-a-mouse-model-of-multiple-sclerosis
#7
Sanaz Afraei, Antimo D'Aniello, Reza Sedaghat, Parvin Ekhtiari, Gholamreza Azizi, Nakisa Tabrizian, Laura Magliozzi, Zahra Aghazadeh, Abbas Mirshafiey
Experimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis. EAE is mainly mediated by adaptive and innate immune responses that leads to an inflammatory demyelization and axonal damage. The aim of the present research was to examine the therapeutic efficacy of D-aspartic acid (D-Asp) on a mouse EAE model. EAE induction was performed in female C57BL/6 mice by myelin 40 oligodendrocyte glycoprotein (35-55) in a complete Freund's adjuvant emulsion, and D-Asp was used to test its efficiency in the reduction of EAE...
July 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28911654/extraction-optimization-of-gallic-acid-catechin-%C3%A2-procyanidin-b2-epicatechin-epigallocatechin-gallate-and-epicatechin-gallate-their-simultaneous-identification-and-quantification-in-saraca-asoca
#8
Tushar Dhanani, Raghuraj Singh, Satyanshu Kumar
The objective of the present investigation was to optimize extraction conditions for maximum recovery of bioactive phenolics from different parts of Saraca asoca. Extraction recovery was optimized using a mixture of methanol and water in different proportions. For identification and quantification of six analytes, a rapid reversed phase ultra-performance liquid chromatography (UPLC) photo diode array detection method was developed. UPLC separation was achieved in a gradient elution mode on a C18 column with acetonitrile and aqueous phosphoric acid (0...
July 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28911653/assessment-of-rosehips-based-on-the-content-of-their-biologically-active-compounds
#9
Apurva Bhave, Vera Schulzova, Hana Chmelarova, Libor Mrnka, Jana Hajslova
In this study, an in-depth analysis of the unique set of rosehip samples from 71 Rosa genotypes was conducted with the aim to identify the most suitable ones for applications in the food and pharmaceutical industries based on the content of biologically active compounds. In the first part of our experiments, the antioxidant activity was determined by 2,2-diphenyl-1-picrylhydrazyl assay and the genotypes with the highest values were selected for the follow-up analysis. In the second part of experiments, the major classes of biologically active compounds in rosehips such as carotenoids, tocopherols, flavonoids, and triterpenoic acids were further quantified using liquid chromatography-based techniques...
July 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28911652/microbiological-histological-and-biochemical-evidence-for-the-adverse-effects-of-food-azo-dyes-on-rats
#10
Khaled Elbanna, Osama Mohamed Sarhan, Manal Khider, Mohamed Elmogy, Hussein Hasan Abulreesh, Mohamed Rabie Shaaban
In this study, 120 lactic acid bacterial strains from different fermented dairy products as well as 10 bacterial intestinal isolates were evaluated for in vitro and in vivo degradation of various food azo dyes. Of these isolates, lactic acid bacteria (LAB) strains 13 and 100 and the intestinal isolates Ent2 and Eco5 exhibited 96-98% degradation of the tested food azo dyes within 5-6 hours. High performance liquid chromatography mass spectra of sunset yellow (E110) and carmoisine (E122) anaerobic degradation products by the intestinal isolates showed that they were structurally related to toxic aromatic amines...
July 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28911651/microencapsulation-of-fish-oil-using-supercritical-antisolvent-process
#11
Fahim Tamzeedul Karim, Kashif Ghafoor, Sahena Ferdosh, Fahad Al-Juhaimi, Eaqub Ali, Kamaruzzaman Bin Yunus, Mir Hoseini Hamed, Ashraful Islam, Mohammad Asif, Mohammed Zaidul Islam Sarker
In order to improve the encapsulation process, a newly supercritical antisolvent process was developed to encapsulate fish oil using hydroxypropyl methyl cellulose as a polymer. Three factors, namely, temperature, pressure, and feed emulsion rate were optimized using response surface methodology. The suitability of the model for predicting the optimum response value was evaluated at the conditions of temperature at 60°C, pressure at 150 bar, and feed rate at 1.36 mL/min. At the optimum conditions, particle size of 58...
July 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28911650/time-course-effects-of-fermentation-on-fatty-acid-and-volatile-compound-profiles-of-cheonggukjang-using-new-soybean-cultivars
#12
Kye Man Cho, Ho-Jeong Lim, Mi-So Kim, Da Som Kim, Chung Eun Hwang, Sang Hae Nam, Ok Soo Joo, Byong Won Lee, Jae Kyeom Kim, Eui-Cheol Shin
In this study, we investigated the effects of the potential probiotic Bacillus subtilis CSY191 on the fatty acid profiles of Cheonggukjang, a fermented soybean paste, prepared using new Korean brown soybean cultivars, protein-rich cultivar (Saedanbaek), and oil-rich cultivar (Neulchan). Twelve fatty acids were identified in the sample set-myristic, palmitic, palmitoleic, stearic, oleic, vaccenic, linoleic, α-linolenic, arachidic, gondoic, behenic, and lignoceric acids-yet, no specific changes driven by fermentation were noted in the fatty acid profiles...
July 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28911649/long-chain-bases-from-sea-cucumber-mitigate-endoplasmic-reticulum-stress-and-inflammation-in-obesity-mice
#13
Shiwei Hu, Jinhui Wang, Jingfeng Wang, Changhu Xue, Yuming Wang
Endoplasmic reticulum (ER) stress and inflammation can induce hyperglycemia. Long-chain bases (LCBs) from sea cucumber exhibit antihyperglycemic activities. However, their effects on ER stress and inflammation are unknown. We investigated the effects of LCBs on ER stress and inflammatory response in high-fat, fructose diet-induced obesity mice. Reactive oxygen species and free fatty acids were measured. Inflammatory cytokines in serum and their mRNA expressions in epididymal adipose tissues were investigated...
July 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28911648/induction-of-g2-m-arrest-and-apoptosis-through-mitochondria-pathway-by-a-dimer-sesquiterpene-lactone-from-smallanthus-sonchifolius-in-hela-cells
#14
Yurika Kitai, Xia Zhang, Yushi Hayashida, Yoshiyuki Kakehi, Hirotoshi Tamura
Dimer sesquiterpene lactones (SLs), uvedafolin and enhydrofolin, against four monomer SLs isolated from yacon, Smallanthus sonchifolius, leaf were the most cytotoxic substances on HeLa cells (IC50 values 2.96-3.17 μM at 24 hours). However, the cytotoxic mechanism of dimer SL has not been elucidated yet. Therefore, in this study, we clarified the in vitro cytotoxic mechanism of uvedafolin on the HeLa cells, and evaluated the cytotoxicity against NIH/3T3 cells which were used as normal cells. In consequence, the dimer SLs had low toxicity for the NIH/3T3 cells (IC50 4...
July 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28911647/characterization-and-hepatoprotective-activity-of-anthocyanins-from-purple-sweet-potato-ipomoea-batatas-l-cultivar-eshu-no-8
#15
Lin Wang, Ying Zhao, Qing Zhou, Chun-Li Luo, Ai-Ping Deng, Zi-Cheng Zhang, Jiu-Liang Zhang
The hepatoprotective activity of anthocyanin-rich purple sweet potato extract (APSPE) was demonstrated. Sixty mice were randomly divided into six groups: control group [without carbon tetrachloride (CCl4) or APSPE]; model group (with CCl4 only); positive control group (50 mg/kg body weight silymarin); low-dose group (100 mg/kg body weight APSPE); medium-dose group (200 mg/kg body weight APSPE); and high-dose group (400 mg/kg body weight APSPE). After 10 days intragastric administration of the respective supplements, the mice in all groups except control were injected intraperitoneally with CCl4 (0...
July 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28911646/evaluating-the-urate-lowering-effects-of-different-microbial-fermented-extracts-in-hyperuricemic-models-accompanied-with%C3%A2-a%C3%A2-safety-study
#16
Rong-Jane Chen, Mei-Huei Chen, Yen-Lin Chen, Ching-Mao Hsiao, Hsiu-Min Chen, Siao-Jhen Chen, Ming-Der Wu, Yi-Jen Yech, Gwo-Fang Yuan, Ying-Jan Wang
Uric acid (UA) is an end product of purine metabolism by the enzyme xanthine oxidase (XOD). Hyperuricemia is characterized by the accumulation of serum UA and is an important risk factor for gout and many chronic disorders. XOD inhibitors or uricase (catalyzes UA to the more soluble end product) can prevent these chronic diseases. However, currently available hypouricemic agents induce severe side effects. Therefore, we developed new microbial fermented extracts (MFEs) with substantial XOD inhibition activity from Lactobacillus (MFE-21) and Acetobacter (MFE-25), and MFE-120 with high uricase activity from Aspergillus...
July 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28911645/antibiofilm-activity-of-cashew-juice-pulp-against-staphylococcus-aureus-high-performance-liquid-chromatography-diode-array-detection-and-gas-chromatography-mass-spectrometry-analyses-and-interference-on-antimicrobial-drugs
#17
Marcus V Dias-Souza, Renan M Dos Santos, Ezequias P de Siqueira, Pedro H Ferreira-Marçal
The epidemiology of Staphylococcus aureus infections has evolved in recent years, as this species is a major Gram-positive pathogen associated with healthcare services. The antimicrobial resistance of this species raises an urgent need for new treatment strategies. Fruits play important nutritional and economic roles in society, but their biological and pharmacological features are poorly explored when compared to nonedible parts of plants such as barks and leaves. In this study, we show that the cashew apple juice [cashew juice pulp (CJP)] extract is active against the planktonic cells of S...
July 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28911644/nephroprotective-effect-of-paeonia-emodi-via-inhibition-of-advanced-glycation-end-products-and-oxidative-stress-in-streptozotocin-nicotinamide-induced-diabetic-nephropathy
#18
Lalit Kishore, Navpreet Kaur, Randhir Singh
The present study aimed to evaluate the effect of alcohol (PA) and hydroalcohol (PHA) extract of Paeonia emodi Royale roots in treatment of streptozotocin-nicotinamide induced diabetic nephropathy. Diabetes mellitus was induced in male Wistar rats by streptozotocin (65 mg/kg intraperitoneally) 15 minutes after nicotinamide (230 mg/kg, intraperitoneally) administration and diabetic nephropathy was assessed by measuring serum glucose, renal parameters (urea, uric acid, creatinine, and blood urea nitrogen level) and lipid profile...
July 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28911643/cytotoxic-and-antioxidant-capacity-of-camel-milk-peptides-effects-of-isolated-peptide-on-superoxide-dismutase-and-catalase-gene-expression
#19
Masoud Homayouni-Tabrizi, Ahmad Asoodeh, Mozhgan Soltani
Peptides from natural sources such as milk are shown to have a wide spectrum of biological activities. In this study, three peptides with antioxidant capacity were identified from camel milk protein hydrolysate. Pepsin and pancreatin were used for hydrolysis of milk proteins. Ultrafiltration and reverse-phase high-performance liquid chromatography were used for the concentration and purification of the hydrolysate, respectively. Sequences of the three peptides, which were determined by matrix-assisted laser desorption/ionization time-of-flight spectrophotometry, were LEEQQQTEDEQQDQL [molecular weight (MW): 1860...
July 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28911642/lactobacillus-pentosus-gmnl-77-inhibits-skin-lesions-in%C3%A2-imiquimod-induced-psoriasis-like-mice
#20
Yi-Hsing Chen, Chieh-Shan Wu, Ya-Husan Chao, Chi-Chen Lin, Hui-Yun Tsai, Yi-Rong Li, Yi-Zhen Chen, Wan-Hua Tsai, Yu-Kuo Chen
Psoriasis, which is regarded as a T-cell-mediated chronic inflammatory skin disease, is characterized by hyperproliferation and poor differentiation of epidermal keratinocytes. In this study, we aimed to determine the in vivo effect of a potentially probiotic strain, Lactobacillus pentosus GMNL-77, in imiquimod-induced epidermal hyperplasia and psoriasis-like skin inflammation in BALB/c mice. Oral administration of L. pentosus GMNL-77 significantly decreased erythematous scaling lesions. Real-time polymerase chain reaction showed that treatment with L...
July 2017: Journal of Food and Drug Analysis
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