journal
https://read.qxmd.com/read/38317493/central-nervous-system-dissemination-of-solitary-sporadic-supratentorial-hemangioblastoma-a-case-report-and-literature-review
#1
Seong-Chan Jung, In-Young Kim, Shin Jung, Tae-Young Jung, Kyung-Sub Moon, Yeong-Jin Kim, Sue-Jee Park, Kyung-Hwa Lee
We report a patient with whole neuroaxis dissemination of a sporadic supratentorial hemangioblastoma (HB) for more than 15 years. A 68-year-old female patient presented with severe radiating pain in the right leg. Gadolinium-enhanced lumbar spine MRI showed an intradural mass (2.5 cm in diameter) at the L4 level. The patient had been severely disabled for 22 years after a previous intraventricular brain tumor resection. At that time, the diagnosis was angioblastic meningioma, which was thought to be incorrect...
January 2024: Brain Tumor Research and Treatment
https://read.qxmd.com/read/38317492/awake-surgery-for-angiocentric-glioma-in-the-eloquent-area-in-an-adolescent-a-case-report
#2
Yuma Yano, Ryosuke Matsuda, Fumi Okada, Maiko Takeda, Ryosuke Maeoka, Ichiro Nakgawa
Angiocentric glioma (AG) is an extremely rare tumor that often develops in adolescents. Awake surgery for AG occurring in the eloquent area has not been reported to date. We report a case involving a right-handed 15-year-old boy with AG. He presented with a first-time generalized tonic-clonic seizure and was rushed to the local hospital. CT of the head indicated a left frontal low-density mass with no calcification. He was subsequently referred to our hospital. Comparison with a CT scan obtained two years prior due to mild head trauma indicated that the lesion showed a trend toward enlargement...
January 2024: Brain Tumor Research and Treatment
https://read.qxmd.com/read/38317491/lynch-syndrome-associated-glioblastoma-treated-with-concomitant-chemoradiotherapy-and-immune-checkpoint-inhibitors-case-report-and-review-of-literature
#3
Kenta Nakase, Ryosuke Matsuda, Shoh Sasaki, Ichiro Nakagawa
Lynch syndrome (LS) is an autosomal dominant disorder caused by mutations in mismatch repair (MMR) genes and is also known to be associated with glioblastomas. The efficacy of immunotherapy for LS-associated glioblastomas remains unknown. Herein, we report a rare case of LS-associated glioblastoma, treated with chemotherapy using immune checkpoint inhibitors (ICI). A 41-year-old female patient presented with headaches and sensory disturbances in the right upper limb for 6 weeks. She had been treated for rectal cancer and had a family history of LS...
January 2024: Brain Tumor Research and Treatment
https://read.qxmd.com/read/38317490/intracranial-involvement-of-systemic-hodgkin-lymphoma-a-case-report-and-literature-review
#4
Hwanhee Lee, Sangjun Ahn, Seung Heon Cha, Won Ho Cho
A 27-year-old male patient, previously diagnosed with Hodgkin lymphoma (HL), presented with gait disturbance. Brain MRI showed a 4.5 cm mass lesion in the right occipital lobe, suggesting either intracranial involvement of HL or a potential meningioma. Despite high-dose methotrexate and steroid treatment, the patient's symptoms persisted, and imaging showed an enlarging mass, leading to surgical intervention. Histopathological examination confirmed central nervous system (CNS) involvement of HL. Postoperatively, the patient underwent whole-brain radiotherapy and demonstrated marked clinical improvement...
January 2024: Brain Tumor Research and Treatment
https://read.qxmd.com/read/38317489/spontaneous-regression-of-glioma-mimicking-brainstem-lesion-in-a-child-a-case-report
#5
Sung Hyun Kang, Hyeon Jin Park, Jae-Won Hyun, Ho-Shin Gwak
Differential diagnosis of focal brainstem lesions detected on MRI is challenging, especially in young children. Formerly, brainstem gliomas were classified mainly based on MRI features and location. However, since 2016, the World Health Organization's brainstem lesion classification requires tissue biopsy to reveal molecular characteristics. Although modern techniques of stereotactic or navigation-guided biopsy ensure accurate biopsy of the lesion with safety, biopsy of brainstem lesions is still generally not performed...
January 2024: Brain Tumor Research and Treatment
https://read.qxmd.com/read/38317488/temporal-analysis-of-postoperative-outcomes-with-or-without-intraoperative-motor-evoked-potentials-and-somatosensory-evoked-potentials-monitoring-for-intracranial-meningioma-surgery
#6
JOURNAL ARTICLE
Na Il Shin, Hye Jin Hong, Young Il Kim, Il Sup Kim, Jae Hoon Sung, Sang Won Lee, Seung Ho Yang
BACKGROUND: This study aimed to retrospectively assess results of intracranial meningioma surgery with or without intraoperative neuromonitoring (IONM) in a single institution. METHODS: Two cohorts (a historical cohort and a monitoring cohort) were collected for the analysis. Before IONM was introduced, a total of 107 patients underwent intracranial meningioma operation without IONM from January 2000 to December 2008 by one neurosurgeon (historical cohort). After IONM was introduced, a total of 99 patients with intracranial meningioma were operated under IONM between November 2018 and February 2023 by two neurosurgeons (monitoring cohort)...
January 2024: Brain Tumor Research and Treatment
https://read.qxmd.com/read/38317487/suggestion-of-follow-up-period-in-nonfunctioning-pituitary-incidentaloma-based-on-mri-characteristics
#7
JOURNAL ARTICLE
Hyunchul Jung, Seung-Yeob Yang, Keun-Tae Cho
BACKGROUND: For patients diagnosed with asymptomatic, non-functional pituitary incidentaloma (PI), periodic follow-up is generally proposed. However, the recommended follow-up period differs among existing guidelines and consensus is lacking. Thus, this study aimed to suggest follow-up periods for PI based on MRI characteristics. METHODS: Between 2007 and 2023, 245 patients who were diagnosed with PI were retrospectively assessed. Their mean clinical and neuroradiological follow-up periods were 74...
January 2024: Brain Tumor Research and Treatment
https://read.qxmd.com/read/38317486/comprehensive-molecular-genetic-analysis-in-glioma-patients-by-next-generation-sequencing
#8
JOURNAL ARTICLE
Taeeun Kim, Ahwon Lee, Stephan Ahn, Jae Sung Park, Sin Soo Jeun, Youn Soo Lee
BACKGROUND: Glioma is caused by multiple genomic alterations. The evolving classification of gliomas emphasizes the significance of molecular testing. Next generation sequencing (NGS) offers the assessment of parallel combinations of multiple genetic alterations and identifying actionable mutations that guide treatment. This study comprehensively analyzed glioma patients using multi-gene NGS panels, providing powerful insights to inform diagnostic classification and targeted therapies...
January 2024: Brain Tumor Research and Treatment
https://read.qxmd.com/read/38317485/clinical-practice-guidelines-for-brain-metastasis-from-solid-tumors
#9
REVIEW
Kyoung Su Sung
With advancements in systemic cancer therapies, the incidence and diagnosis of brain metastases (BMs) have increased, necessitating updated clinical practice guidelines. There also were developments in neurosurgical and radiotherapeutic modalities for intracranial lesions, as well as advances in immune and targeted therapies for BMs of systemic cancers. Recently, the ASCO-SNO-ASTRO and EANO-ESMO have published clinical guidelines for BMs from solid tumors. The ASCO-SNO-ASTRO guidelines, published in 2021, underwent a systematic literature review and critical evaluation by their Expert Panel, addressing the key questions in various therapies such as surgery, radiotherapy, and systemic therapy for the recommendations...
January 2024: Brain Tumor Research and Treatment
https://read.qxmd.com/read/38317484/basics-for-pediatric-brain-tumor-imaging-techniques-and-protocol-recommendations
#10
REVIEW
Ah Young Jung
This review provides an overview of the current state of pediatric brain tumor imaging, emphasizing the role of various imaging sequences and highlighting the advantages of standardizing protocols for pediatric brain tumor imaging in diagnosis and treatment response evaluation. Basic anatomical sequences such as pre- and post-contrast 3D T1-weighted, T2-weighted, fluid-attenuated inversion recovery, T2*-weighted, and diffusion-weighted imaging (DWI), are fundamental for assessing tumor location, extent, and characteristics...
January 2024: Brain Tumor Research and Treatment
https://read.qxmd.com/read/37953454/awake-surgery-for-lesional-epilepsy-in-resource-limited-settings-case-report-and-review-of-literature
#11
Mohammad Hamza Bajwa, Syeda Amrah Hashmi, Abdullah Nisar, Muhammad Waqas Baqai, Saqib Kamran Bakhshi, Muskaan Abdul Qadir, Faraz Shafiq, Syed Ather Enam
Epilepsy surgery is a well-established treatment for drug-resistant epilepsy, with awake craniotomy being used in certain cases to remove epileptogenic foci while preserving crucial brain functions. We are presenting the first reported case from Pakistan of a 19-year-old woman who underwent awake epilepsy surgery to treat cortical dysplasia. She had a history of generalized tonic-clonic seizures since her childhood and was referred to our clinic due to an increase in seizure frequency. EEG and MRI identified the epileptogenic focus in the right parieto-temporal region...
October 2023: Brain Tumor Research and Treatment
https://read.qxmd.com/read/37953453/primary-intracranial-ewing-sarcoma-with-ewsr1-fli1-gene-translocation-mimicking-a-meningioma-and-a-multidisciplinary-therapeutic-approach-a-case-report-and-systematic-review-of-literatures
#12
Changjun Hyun, Yeonju Lee, Ho Kang, Hyun Joo Park, Koung Jin Suh, Byung Se Choi, Gheeyoung Choe, Chae-Yong Kim
Ewing sarcoma and peripheral primitive neuroectodermal tumor (ES/pPNET) is an undifferentiated malignant tumor that is most prevalent in children and young adults and often radiologically mimics a meningioma. A 38-year-old female patient visited our hospital with complaints of right-sided tinnitus, right hemiparesis, and imbalance. She underwent preoperative imaging and was subsequently diagnosed as having a meningioma on the petrous ridge. After partial resection, EWSR1-FLI1 gene fusion was confirmed, and she was diagnosed with ES/pPNET...
October 2023: Brain Tumor Research and Treatment
https://read.qxmd.com/read/37953452/extensive-leptomeningeal-spreading-of-ependymoma-in-an-adult-case-report-and-literature-review
#13
Joonseo Kang, Kwon Woo Lee, Yeongu Chung, Yusam Won, Je Beom Hong
Ependymoma is a rare adult tumor that originates from ependymal cells of the central nervous system, primarily occurring in the cerebral ventricles or the central canal of the spinal cord. In this paper, we report a case of extensive leptomeningeal seeding of ependymoma of a 39-year-old male patient, in whom the tumor was found incidentally after head trauma. The MRI exhibited diffuse leptomeningeal infiltrative lesions along with bilateral multiple cerebral sulci, basal cisterns, cerebellopontine angle, cerebellar folia...
October 2023: Brain Tumor Research and Treatment
https://read.qxmd.com/read/37953451/massive-hyperostotic-meningioma-en-plaque-mimicking-fibrous-dysplasia
#14
Ju In Park, Chang Kyu Park, Bong Jin Park, Seok Keun Choi
The authors report an extremely rare case of a massive hyperostotic meningioma en plaque, which had characteristics of unique bony growth. A 34-year-old man presented with a palpable solid mass in the left cranial region that had gradually grown in size with a broad base on the calvarium for 8 years. Radiologically, the area involved by the mass ranged from the sphenoid bone to the frontal, parietal, temporal, and occipital bones. Three-dimensional CT revealed multiple growing spiculate features on the inner and outer cranial surface...
October 2023: Brain Tumor Research and Treatment
https://read.qxmd.com/read/37953450/recurrence-of-rathke-s-cleft-cyst-following-surgery-and-histopathological-considerations-for-recurrence-a-case-presentation
#15
Dongwook Lee, Jang Hun Kim, Dong-Hyuk Park, Shin-Hyuk Kang, Kyung-Jae Park
Recurrence of Rathke's cleft cysts (RCC) following surgery is not uncommon. We present a 33-year-old male patient with chronic headache and visual disturbances whose MRI showed mostly cystic, suprasellar mass with peripheral enhancement. Endoscopic extended transsphenoidal approach and tumor resection was performed and RCC was pathologically confirmed postoperatively. Early recurrence was first suspected at 3 months following surgery, and his serial MRIs showed a recurred mass without associated clinical symptoms...
October 2023: Brain Tumor Research and Treatment
https://read.qxmd.com/read/37953449/survival-and-malignant-transformation-of-pineal-parenchymal-tumors-a-30-year-retrospective-analysis-in-a-single-institution
#16
JOURNAL ARTICLE
Tae-Hwan Park, Seung-Ki Kim, Ji Hoon Phi, Chul-Kee Park, Yong Hwy Kim, Sun Ha Paek, Chang-Hyun Lee, Sung-Hye Park, Eun Jung Koh
BACKGROUND: This study aims to elucidate clinical features, therapeutic strategies, and prognosis of pineal parenchymal tumors (PPT) by analyzing a 30-year dataset of a single institution. METHODS: We reviewed data from 43 patients diagnosed with PPT at Seoul National University Hospital between 1990 and 2020. We performed survival analyses and assessed prognostic factors. RESULTS: The cohort included 10 patients with pineocytoma (PC), 13 with pineal parenchymal tumor of intermediate differentiation (PPTID), and 20 with pineoblastoma (PB)...
October 2023: Brain Tumor Research and Treatment
https://read.qxmd.com/read/37953448/treatment-outcome-of-the-brain-metastases-in-peri-rolandic-area-comparison-between-surgery-and-stereotactic-radiosurgery
#17
JOURNAL ARTICLE
Jun Hyeok Jung, Kawngwoo Park, Eun Young Kim, Chan-Jong Yoo, Gi-Taek Yee, Woo-Kyung Kim, Dong-Won Shin
BACKGROUND: Brain metastases of peri-Rolandic area is crucial as it directly impacts the quality of life for cancer patients. Surgery or stereotactic radiosurgery (SRS) is considered for peri-Rolandic brain metastases as for other brain metastases. However, the benefit of each treatment modality on functional outcome has not been clearly defined for this tumor. The purpose of this study is to compare the functional course of each treatment and to suggest an effective treatment for patients' quality of life...
October 2023: Brain Tumor Research and Treatment
https://read.qxmd.com/read/37953447/value-of-thallium-201-spect-and-spect-ct-brain-imaging-in-differentiating-malignant-from-nonmalignant-lesions-a-comparative-case-series-study-with-pathologic-and-or-clinical-correlation
#18
JOURNAL ARTICLE
Nicole Girlyn T Pang, Julette Marie F Batara, Lara Triccia C Luistro, Christianne V Mojica, Allan Jay C Domingo
BACKGROUND: Thallium-201 single-photon emission computed tomography/computed tomography (SPECT/CT) brain scan is an imaging modality which can be done to differentiate between malignant and nonmalignant lesions among patients with nonconclusive findings on conventional neuroimaging. This study describes the results of thallium-201 SPECT/CT brain imaging and relate it to histopathologic and/or clinical findings and evaluate the value of thallium-201 SPECT/CT brain imaging in differentiating malignant from nonmalignant lesions...
October 2023: Brain Tumor Research and Treatment
https://read.qxmd.com/read/37953446/a-case-series-of-duramatrix-onlay-%C3%A2-plus-in-cranial-surgery-is-associated-with-a-low-complication-profile
#19
JOURNAL ARTICLE
Mahlet Mekonnen, Gabrielle Hovis, Natalie Mahgerefteh, Anubhav Chandla, Yelena Malkhasyan, Ashley B Zhang, Isaac Yang
BACKGROUND: DuraMatrix-Onlay® Plus is a collagen dura membrane derived from purified bovine Achilles tendon. The matrix provides a scaffold for collagen synthesis and is intended to be used as an onlay without the need for dural sutures. The study aims to describe our experience with 33 consecutive patients who underwent a duraplasty procedure using the novel DuraMatrix-Onlay® Plus collagen dura membrane. METHODS: This is a retrospective case series of 33 patients who underwent a duraplasty procedure at a single academic hospital in Los Angeles, CA, USA between May 2016 and March 2017...
October 2023: Brain Tumor Research and Treatment
https://read.qxmd.com/read/37953445/flash-radiotherapy-a-flashing-idea-to-preserve-neurocognitive-function
#20
REVIEW
Hye-Ju Jo, Taerim Oh, Ye-Rim Lee, Gi-Sue Kang, Hye-Joon Park, G-One Ahn
FLASH radiotherapy (FLASH RT) is a technique to deliver ultra-high dose rate in a fraction of a second. Evidence from experimental animal models suggest that FLASH RT spares various normal tissues including the lung, gastrointestinal track, and brain from radiation-induced toxicity (a phenomenon known as FLASH effect), which is otherwise commonly observed with conventional dose rate RT. However, it is not simply the ultra-high dose rate alone that brings the FLASH effect. Multiple parameters such as instantaneous dose rate, pulse size, pulse repetition frequency, and the total duration of exposure all need to be carefully optimized simultaneously...
October 2023: Brain Tumor Research and Treatment
journal
journal
48347
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.