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Brain Tumor Research and Treatment

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https://www.readbyqxmd.com/read/29188216/extra-axial-and-clear-cell-type-ependymoma-mimicking-a-convexity-meningioma
#1
Stephen Ahn, Young Joo Kim, Youn Soo Lee, Sin-Soo Jeun
A 33-year-old woman presented with tingling and paresthesia on left extremity for 2 months. Magnetic resonance imaging revealed that the tumor was iso- and hypo-intensity on T1-weighted image, mixed iso- and high-signal intensity on T2-weighted images and heterogeneously enhanced with rim enhancement. Neither arachnoid cleft nor dural tail was certain but mass was located extra-axially so meningioma was suspected. During operation, tumor wasn't attached to dura at all but arachnoid attachment was seen. Pathologically, clear cell type ependymoma was confirmed...
October 2017: Brain Tumor Research and Treatment
https://www.readbyqxmd.com/read/29188215/astroblastoma-in-a-young-female-patient-a-case-report-and-literature-review-of-clinicopathological-radiological-and-prognostic-characteristics-and-current-treatment-strategies
#2
Muhammad Sadiq, Iftikhar Ahmad, Jamila Shuja, Zubair Ahmad, Riyasat Ahmed, Khushnaseeb Ahmad
Astroblastoma is an uncommon glial tumor with predominant manifestation in the young age. Herein, we report a case of 18-year-old astroblastoma female patient who presented with history of two months headache. Magnetic resonance imaging (MRI) of the brain demonstrated well circumscribed, intra-axial abnormal signal intensity lesion (size=5×4 cm2) in the right parieto-occipital region of the brain. The patient underwent complete surgical resection of the gross tumor, as confirmed by an early post-surgical MRI (i...
October 2017: Brain Tumor Research and Treatment
https://www.readbyqxmd.com/read/29188214/subfrontal-schwannoma-extended-broadly-to-nasal-cavity-treated-by-gamma-knife-radiosurgery-following-surgical-excision-a-case-report
#3
Soo Hee Kim, Jung Hwan Lee, Soon Ki Sung, Chang Hwa Choi
Subfrontal schwannomas are rarely reported. They are usually found only in the subfrontal area, but some extend to the nasal cavity. In these cases, prevention of postoperative cerebrospinal fluid (CSF) leakage through thinned or eroded anterior skull base is important. A 51-year-old female with anosmia and mild nausea was diagnosed as subfrontal extraaxial mass with nasal cavity extension. This mass was initially thought to be an olfactory groove meningioma. We performed a bifrontal craniotomy for surgical excision...
October 2017: Brain Tumor Research and Treatment
https://www.readbyqxmd.com/read/29188213/pituicytoma-with-significant-tumor-vascularity-mimicking-pituitary-macroadenoma
#4
Hyuk Ki Shim, Seung Heon Cha, Won Ho Cho, Sung-Hye Park
A 19-year-old man presented with bitemporal hemianopsia and was found to have a large sellar and suprasellar tumor, resembling a pituitary macroadenoma. Emergency transsphenoidal approach was attempted because of rapid visual deterioration with headache. However, the approach was complicated and stopped by uncontrolled hemorrhage from the tumor. After conventional cerebral angiography and recognition of an unusual pathology, transcranial approach was achieved to prevent permanent visual loss. The final pathological diagnosis was pituicytoma with epithelioid features...
October 2017: Brain Tumor Research and Treatment
https://www.readbyqxmd.com/read/29188212/supratentorial-pilocytic-astrocytoma-mimicking-convexity-meningioma-with-early-anaplastic-transformation-a-case-report
#5
Jung Hwan Lee, Soon Ki Sung, Chang Hwa Choi
Meningiomas and pilocytic astrocytomas are benign intracranial tumors. Pilocytic astrocytomas arises frequently at the posterior fossa in childhood. Meningiomas have several image findings, such as a dural tail sign, bony erosion, and sunburst appearance on angiography. However, pilocytic astrocytomas with these findings have been rarely reported. In this report, we describe a mass with typical image findings of a meningioma, but diagnosed as a supratentorial pilocytic astrocytoma with early anaplastic transformation...
October 2017: Brain Tumor Research and Treatment
https://www.readbyqxmd.com/read/29188211/response-of-leptomeningeal-dissemination-of-anaplastic-glioma-to-temozolomide-experience-of-two-cases
#6
Jin Woo Bae, Eun Kyung Hong, Ho-Shin Gwak
The incidence of leptomeningeal dissemination (LMD) of anaplastic glioma has been increasing. LMD can be observed at the time of initial presentation or the time of recurrence. As a result of both rarity and unusual presentation, a standard therapy has not yet been suggested. In contrast to leptomeningeal carcinomatosis for systemic solid cancers, a relatively prolonged survival is observed in some patients with LMD of anaplastic gliomas. Treatment modalities include whole craniospinal irradiation, intra-cerebrospinal fluid (CSF) chemotherapy, and systemic chemotherapy...
October 2017: Brain Tumor Research and Treatment
https://www.readbyqxmd.com/read/29188210/pituitary-ependymoma-10-year-follow-up-after-partial-resection-and-radiation-therapy
#7
Jong Seok Lee, Kwan Ho Cho, Eun Kyung Hong, Sang-Hoon Shin
Ependymoma usually arises within the ventricles and central canal of the spinal cord. These tumors, found in the sellar region, are extremely rare. We report a case of pituitary ependymoma followed up over 10 years. A 59-year-old male patient presented with fatigue, general weakness, erectile dysfunction, and loss of body hair, including pubic hair. Brain magnetic resonance imaging (MRI) revealed a 3.3×3.5×2.3-cm sellar and suprasellar snowman-shaped enhancing mass. The tumor was partially resected via the trans-sphenoidal approach followed by postoperative radiation therapy...
October 2017: Brain Tumor Research and Treatment
https://www.readbyqxmd.com/read/29188209/outcomes-in-20-gynecologic-cancer-patient-with-brain-metastasis-a-single-institution-retrospective-study
#8
Seung Bin Kim, Kihwan Hwang, Jin-Deok Joo, Jung Ho Han, Yong Beom Kim, Chae-Yong Kim
Background: The incidence of brain metastasis (BM) in gynecologic cancers has risen recently, due to prolonged survival times and an early diagnosis. We analyzed treatment outcomes of patients with BM from gynecologic cancers. Methods: Among 951 patients with BM who were treated in neurosurgical department from July 2003 to February 2016, a total of 20 (2%) patients were from gynecologic cancers. The patients' clinical characteristics were collected by using medical records...
October 2017: Brain Tumor Research and Treatment
https://www.readbyqxmd.com/read/29188208/the-clinical-outcome-of-hydroxyurea-chemotherapy-after-incomplete-resection-of-atypical-meningiomas
#9
Jungook Kim, Kyu Hong Kim, Young Zoon Kim
Background: The aim of this study is to investigate the clinical results of adjuvant chemotherapy with hydroxyurea and to compare those with the results of postoperative radiotherapy after incomplete resection of atypical meningiomas (ATMNGs). Methods: We retrospectively reviewed the medical records of 84 patients with ATMNGs diagnosed in the period from January 2000 to December 2014. Clinical data included patient sex and age at the time of surgery, presenting symptoms at diagnosis, location and size of tumor, extent of surgery, use of postoperative radiotherapy or hydroxyurea chemotherapy, duration of follow-up, and progression...
October 2017: Brain Tumor Research and Treatment
https://www.readbyqxmd.com/read/29188207/ependymomas-prognostic-factors-and-outcome-analysis-in-a-retrospective-series-of-33-patients
#10
Yong-Hyun Chai, Shin Jung, Jung-Kil Lee, In-Young Kim, Woo-Youl Jang, Kyung-Sub Moon, Jae-Hyoo Kim, Kyung-Hwa Lee, Seul-Kee Kim, Tae-Young Jung
Background: The purpose of this study was to evaluate the prognostic factors and outcomes in patients with ependymoma to management plans. Methods: Between 1997 and 2013, 33 patients with 25 ependymomas (WHO grade II) and eight anaplastic ependymomas (WHO grade III) were pathologically diagnosed. Six were pediatric patients (mean age, 6.15 years; range, 1.3-11 years), while 27 were adults (mean age, 47.5 years; range, 19-70 years). Of those, there were 12 adult patients with totally resected ependymomas without anaplastic pathology and adjuvant treatment...
October 2017: Brain Tumor Research and Treatment
https://www.readbyqxmd.com/read/29188206/genomic-and-molecular-characterization-of-brain-tumors-in-asian-and-non-asian-patients-of-los-angeles-a-single-institution-analysis
#11
Courtney Duong, Thien Nguyen, John P Sheppard, Vera Ong, Lawrance K Chung, Daniel T Nagasawa, Isaac Yang
Background: Worldwide, approximately 2% of new cancers are of the brain. Five-year survival rates among brain cancer patients have been reported as a little over a third. Differences in clinical outcomes between brain tumor patients of different races remain poorly understood. Methods: A retrospective chart review was performed on brain tumor resection patients≥18 years old. Demographics, treatment variables, and survival outcomes were collected. Primary outcomes were length of stay, recurrence rate, progression-free survival (PFS), and overall survival (OS)...
October 2017: Brain Tumor Research and Treatment
https://www.readbyqxmd.com/read/29188205/recurred-intracranial-meningioma-a-retrospective-analysis-for-treatment-outcome-and-prognostic-factor
#12
Hyun-Seung Ryu, Kyung-Sub Moon, Kyung-Hwa Lee, Woo-Youl Jang, Tae-Young Jung, In-Young Kim, Shin Jung
Background: In this study, we aimed to compare repeated resection and radiation treatment, such as Gamma knife radiosurgery (GKRS) or conventional radiotherapy (RT), and investigate the factors influencing treatment outcome, including overall survival (OS), progression-free survival (PFS), and complication rates. Methods: We retrospectively reviewed 67 cases of recurred intracranial meningiomas (repeated resection: 36 cases, radiation treatment: 31 cases) with 56 months of the median follow-up duration (range, 13-294 months)...
October 2017: Brain Tumor Research and Treatment
https://www.readbyqxmd.com/read/29188204/greetings-from-the-new-editor-in-chief
#13
EDITORIAL
Jeong-Hyun Hwang
No abstract text is available yet for this article.
October 2017: Brain Tumor Research and Treatment
https://www.readbyqxmd.com/read/28516081/a-case-of-coincidental-intrasellar-chordoma-and-pituitary-adenoma
#14
Sehoon Park, Hee Sung Kim, Ki-Su Park, Taek-Kyun Nam, Yong-Sook Park, Jeong-Taik Kwon, Kyung-Tae Kim
Although chordomas are midline tumors, primarily intrasellar chordomas are extremely rare. In this report, the authors describe the case of a 68-year-old female with partial abducens nerve palsy in the right eye due to the intrasellar cystic tumor. After endonasal trans-sphenoidal surgery, intraoperative and histopathological findings confirmed the co-occurrence of an entirely intrasellar chordoma and pituitary adenoma. To our knowledge, the present case is the third reported case of an intrasellar chordoma with a pituitary adenoma...
April 2017: Brain Tumor Research and Treatment
https://www.readbyqxmd.com/read/28516080/cutaneous-anaplastic-large-t-cell-lymphoma-with-invasion-of-the-central-nervous-system-a-case-report
#15
Hyun-Nam Seo, Jin-Ho Seo, Cheol-Young Lee, Jihye Song, Jong-Hyun Kim, Hyun-Woo Kim
Anaplastic large T-cell lymphoma (ALCL) encompasses different clinical entities that can be aggressive or localized. Scalp anaplastic lymphoma kinase (ALK)-negative ALCL is considered a localized lymphoma, and usually extends to the regional lymph nodes; intracranial invasion is rare. A 74-year-old woman was diagnosed with scalp ALK-negative ALCL, but did not exhibit invasion of the lymph nodes. Computed tomography and magnetic resonance imaging revealed intracranial masses with bony erosions. We treated the patient using CHOP chemotherapy and achieved short-term regression of the scalp and intracranial lesions...
April 2017: Brain Tumor Research and Treatment
https://www.readbyqxmd.com/read/28516079/fourth-ventricle-neurenteric-cyst-mimicking-hemangioblastoma
#16
Eugenie Choe, Kihwan Hwang, Gheeyoung Choe, Chae-Yong Kim
This report presents a case of fourth ventricle neurenteric cyst (NE cyst) mimicking hemangioblastoma, which developed in a 50-year-old woman. A tiny enhancing mural portion of the fourth ventricle in MRI suggested that the cyst was hemangioblastoma, but pathological evidence showed that the cyst was in fact NE cyst in the fourth ventricle. In order to make proper decision on to what extent of surgical resection should be done, considering every possibility in differential diagnosis might be helpful. This case reports an unusual pathology in 4th ventricle, considering the patient's age, and demonstrates that a rarer disease may share radiological features of a common disease...
April 2017: Brain Tumor Research and Treatment
https://www.readbyqxmd.com/read/28516078/subependymal-giant-cell-astrocytoma-presenting-with-tumoral-bleeding-a-case-report
#17
Jae-Young Kim, Tae-Young Jung, Kyung-Hwa Lee, Seul-Kee Kim
We report a rare case of subependymal giant cell astrocytoma (SEGA) associated with tumoral bleeding in a pediatric patient without tuberous sclerosis complex (TSC). A 10-year-old girl presented with a 2-week history of an increasingly aggravating headache. Brain magnetic resonance imaging revealed an approximately 3.6-cm, well-defined, heterogeneously enhancing mass with multistage hemorrhages on the right-sided foramen of Monro. The tumor was completely resected using a transcallosal approach. Intraoperatively, the mass presented as a gray-colored firm tumor associated with acute and subacute hemorrhages...
April 2017: Brain Tumor Research and Treatment
https://www.readbyqxmd.com/read/28516077/toxoplasmic-encephalitis-in-patient-with-acquired-immunodeficiency-syndrome
#18
Sang-Bok Lee, Tae-Gyu Lee
Toxoplasmic encephalitis (TE) is an opportunistic infection found in immunocompromised patients and TE related cerebral mass lesion is often reported in acquired immunodeficiency acquired immunodeficiency syndrome (AIDS) patients. However, incidence of TE related AIDS in Korea is still rare and is unfamiliar to neurosurgeons. Differential diagnosis is needed to rule out other brain lesions. A 39-year-old man visited the emergency room with rapid progressive left hemiparesis. Magnetic resonance imaging showed a ring-enhanced mass lesion in his right frontal lobe...
April 2017: Brain Tumor Research and Treatment
https://www.readbyqxmd.com/read/28516076/primary-central-nervous-system-vasculitis-mimicking-a-cortical-brain-tumor-a-case-report
#19
Joo-Seok Lee, Tae-Young Jung, Kyung-Hwa Lee, Seul-Kee Kim
We report a case of primary central nervous system vasculitis (PCNSV) mimicking a cortical brain tumor. A 25-year-old woman presented with a 2-week history of headache and transient right hemiparesis. Brain magnetic resonance imaging (MRI) revealed a cortical-involving lesion on the left frontal lobe. The 6-cm sized lesion showed low signal intensity on T1-weighted images and high signal intensity on T2-weighted images. The lesion had continual linear enhancement on the subcortical white matter and leptomeninges...
April 2017: Brain Tumor Research and Treatment
https://www.readbyqxmd.com/read/28516075/fourth-ventricular-lesions-in-metastatic-gliomas-a-rare-predilection
#20
Mohammed Nazir Khan, Ariane Poulin, Marco Essig
Over the course of five years, a total of ten cases were collected of glioma patients in whom a distant lesion at the fourth ventricle was noted. A 'distant lesion' was defined as a lesion with a normal appearing tissue bridge at imaging between the primary and secondary locations. Previous imaging of these patients was reviewed along with clinical history, course of therapy, and available histology. A review of the literature was performed with respect to present knowledge on patterns of glioma proliferation and dissemination...
April 2017: Brain Tumor Research and Treatment
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